A drug delivery device and dressing set for fecal microbiota transplantation

Abstract

The present disclosure relates to a kind of dosing device and dressing change package for fecal bacteria transplantation, the device includes dosing device head and anal tube;The dosing device head is half-ellipsoidal structure, the half-ellipsoidal structure has arc surface and closed surface, fixed delivery pipe is passed in the top of the arc surface, the head of the fixed delivery pipe is provided with opening;The center of the closed surface is provided with through-hole, to make anal tube pass through;Sponge body is arranged in the inside of fixed delivery pipe located in the dosing device head;The head of the anal tube is circular arc, and a plurality of three-way valve incisions are arranged on the side wall of the head of the anal tube.The dosing device can avoid the problem of drug overflow caused by intestinal resistance during fecal bacteria transplantation, the inside of the device is provided with lubricating liquid, which reduces the work of medical staff and can avoid pollution, effectively improves the efficiency of medical staff on patient fecal bacteria transplantation.

Description

Technical Field

[0001] This disclosure relates to the field of medical assistive device technology, and more specifically, to a drug delivery device and dressing pack for fecal microbiota transplantation. Background Technology

[0002] Fecal microbiota transplantation (FMT) refers to the transplantation of functional bacteria from the feces of healthy individuals into the gastrointestinal tract of patients, thereby rebuilding a new gut microbiota and achieving the treatment of intestinal and extraintestinal diseases.

[0003] The current method of fecal microbiota transplantation requires auxiliary equipment and separate lubrication of the anal canal, making the operation relatively cumbersome; in addition, it is prone to extravasation of the medication. Utility Model Content

[0004] The purpose of this disclosure is to address the aforementioned deficiencies in the prior art by providing a drug delivery device and dressing pack for fecal microbiota transplantation.

[0005] To achieve the above objectives, the first aspect of this disclosure provides a drug delivery device for fecal microbiota transplantation, the device comprising a drug delivery device head and a rectal tube; The head of the drug delivery device has a semi-ellipsoidal structure with an arc-shaped surface and a closed surface. A fixed delivery tube is inserted through the top of the arc-shaped surface, and the head of the fixed delivery tube has an opening. A through hole is provided in the center of the closed surface for the anal tube to pass through. A sponge is provided inside the fixed delivery tube located in the head of the drug delivery device. The head of the anal canal is arc-shaped, and multiple three-way valve incisions are provided on the side wall of the head of the anal canal. An anal canal receiving bag is provided on the outside of the anal canal. The fixed delivery pipe and the sponge are each independently cylindrical.

[0006] Optionally, the number of three-way valve incisions is 4-6.

[0007] Optionally, the tail end of the anal tube is a cylindrical flexible tube with an outer diameter of 3-8 mm and a length of 45-60 cm; graduations are provided on the tail end of the anal tube.

[0008] Optionally, the inner diameter of the fixed delivery tube is larger than the outer diameter of the tail of the anal tube.

[0009] Optionally, the tail end of the anal tube is provided with a connector for connection to a syringe.

[0010] Optionally, the connector is a tee connector.

[0011] Optionally, the sponge body is provided with lubricant.

[0012] Optionally, the connecting end of the anal tube receiving bag is connected to the arc-shaped surface.

[0013] Optionally, a film bag is provided on the outside of the fixed delivery tube near the head of the drug delivery device.

[0014] A second aspect of this disclosure provides a dressing pack for fecal microbiota transplantation, the dressing pack including a receiving box, the receiving box being provided with a first receiving cavity and a second receiving cavity; The first receiving cavity contains a drug delivery device for fecal microbiota transplantation; The second receiving cavity contains a syringe, a three-way connector, and a glove.

[0015] Through the above technical solutions, the drug delivery device for fecal microbiota transplantation disclosed herein can avoid the problem of drug leakage caused by intestinal resistance during fecal microbiota transplantation, allowing any leakage of drug during removal of the rectal tube to be retained for a certain period of time. Furthermore, the device is equipped with a lubricating fluid, reducing the workload of medical staff and preventing contamination. When removing the rectal tube, contaminants can be directly covered with a thin film bag, making operation convenient and avoiding the possibility of contamination for medical staff. The dressing kit of this disclosure includes a drug delivery device, and the syringe can store fecal microbiota, effectively improving the efficiency of fecal microbiota transplantation for patients.

[0016] Other features and advantages of this disclosure will be described in detail in the following detailed description section. Attached Figure Description

[0017] The accompanying drawings are provided to further illustrate the present disclosure and form part of the specification. They are used together with the following detailed description to explain the present disclosure, but do not constitute a limitation thereof. In the drawings: Figure 1 This is a cross-sectional view of the drug delivery device for fecal microbiota transplantation disclosed herein.

[0018] Figure 2 This is a side view of the drug delivery device for fecal microbiota transplantation disclosed herein.

[0019] Figure 3 This is a structural diagram of the dressing pack for fecal microbiota transplantation disclosed herein.

[0020] Explanation of reference numerals in the attached figures 1. Rectal tube; 2. Head of drug delivery device; 3. Rectal tube receiving bag; 4. Opening; 5. Fixed delivery tube; 6. Connector; 7. Sponge body; 8. Film bag; 9. Sealing surface; 10. Arc-shaped surface. Detailed Implementation

[0021] The specific embodiments of this disclosure will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit this disclosure.

[0022] In this disclosure, unless otherwise stated, directional terms such as "inner" and "outer" refer to the inner and outer states under normal use.

[0023] like Figure 1 As shown, the first aspect of this disclosure provides a drug delivery device for fecal microbiota transplantation, the device comprising a drug delivery device head 2 and an anal tube 1; The head 2 of the drug delivery device has a semi-ellipsoidal structure with an arc surface 10 and a closed surface 9. A fixed delivery tube 5 is inserted through the top of the arc surface 10, and the head of the fixed delivery tube 5 is provided with an opening 4. A through hole is provided in the center of the closed surface 9 for the anal tube 1 to pass through. A sponge 7 is provided inside the fixed delivery tube 5 located in the head 2 of the drug delivery device. The head of the anal canal 1 is arc-shaped, and multiple three-way valve incisions are provided on the side wall of the head of the anal canal 1. An anal canal receiving bag 3 is provided on the outside of the anal canal 1. The fixed delivery pipe 5 and the sponge body 7 are each independently cylindrical.

[0024] The drug delivery device for fecal microbiota transplantation disclosed herein can avoid the problem of drug spillage caused by intestinal resistance during fecal microbiota transplantation, and can retain the drug that spills out when the rectal tube is removed for a certain period of time; in addition, the device is equipped with a lubricating fluid, which reduces the workload of medical staff and can avoid contamination; when the rectal tube is removed, the contaminant can be directly covered with a film bag, which is convenient to operate and avoids the possibility of contamination of medical staff.

[0025] In this disclosure, a semi-ellipsoidal structure is provided at the head of the drug delivery device. The semi-ellipsoidal structure is curved and hollow inside, so that any drug that overflows during the withdrawal of the rectal tube can remain for a certain period of time, avoiding drug waste. The semi-ellipsoidal structure can be made of plastic or rubber.

[0026] like Figure 2 As shown, in one embodiment of this disclosure, the fixed delivery tube can be made of elastic rubber or soft silicone. The opening at the head of the fixed delivery tube refers to an opening on the radial cross-section of the head of the cylindrical fixing part; this opening can be a straight-line opening. During use, the rectal tube can be inserted into the intestine through this straight-line opening; when not in use or after the rectal tube is withdrawn, the straight-line opening automatically closes or remains closed. Preferably, the inner diameter of the cylindrical fixing part is 4-10 mm, for example, 4 cm or 5 cm.

[0027] According to this disclosure, a sponge 7 is disposed inside the portion of the fixed delivery tube 5 located within the head 2 of the drug delivery device. The inner diameter of the sponge is smaller than the inner diameter of the fixed delivery tube. Preferably, the inner diameter of the cylindrical sponge can be 2 mm. Lubricating fluid can be disposed on the sponge 7. When the rectal tube passes through the cylindrical sponge, the rectal tube can adhere to the lubricating fluid on the sponge, reducing the workload of medical personnel, preventing contamination, and further improving the work efficiency of medical personnel.

[0028] In one embodiment of this disclosure, the number of three-way valve incisions can be 4-6, for example, 4, 5, or 6. This disclosure uses three-way valve incisions that are closed when no medication is being administered; the incisions remain closed when the rectal tube enters the intestine without medication being administered, preventing blockage due to fecal matter contamination; the incisions automatically open during medication administration, allowing the medication to enter the intestine through the valve opening; and the incisions automatically close when medication administration is complete, preventing damage to the intestinal mucosa caused by the insertion and removal of the rectal tube.

[0029] In one embodiment of this disclosure, the tail end of the anal tube 1 is a cylindrical flexible tube with an outer diameter of 3-8 mm and a length of 45-60 cm; graduations are provided on the tail end of the anal tube 1. This disclosure does not impose specific limitations on the material of the anal tube. For example, the arc-shaped head of the anal tube can be made of a slightly harder material, which makes insertion easier and prevents blockage; the tail end of the anal tube is made of a flexible material, which allows for arbitrary shape changes, facilitating entry into the intestine, and also makes it easy to store.

[0030] According to this disclosure, the inner diameter of the fixed delivery tube 5 is greater than the outer diameter of the tail of the anal tube 1; the inner diameter of the receiving end 7 is greater than the outer diameter of the tail of the anal tube 1.

[0031] In one embodiment of this disclosure, the tail end of the anal tube 1 is provided with a connector 6 for connection to a syringe; preferably, the connector 6 can be a three-way connector.

[0032] In this disclosure, the connection method between connector 6 and syringe is not specifically limited.

[0033] In one embodiment of this disclosure, the connecting end of the anal tube receiving bag 3 is connected to the arc-shaped surface 10. The receiving end of the anal tube receiving bag is used to receive the tail of the anal tube, further effectively preventing contamination of the anal tube.

[0034] To further facilitate the handling of contaminants by medical staff, a thin film bag 8 is provided on the outside of the fixed delivery tube 5 near the head 2 of the drug delivery device. When the rectal tube is withdrawn, medical staff can wrap the contaminants with the thin film bag to effectively prevent contamination of medical staff.

[0035] like Figure 3 As shown, the second aspect of this disclosure provides a dressing pack for fecal microbiota transplantation, the dressing pack including a receiving box, the receiving box being provided with a first receiving cavity and a second receiving cavity; The first receiving cavity contains a drug delivery device for fecal microbiota transplantation; The second receiving cavity contains a syringe, a three-way connector, and a glove.

[0036] In this disclosure, the syringe has a connector that directly connects to the tail end of the anal tube 1 of the fecal microbiota transplantation (FMT) administration device, and the syringe can store and preserve fecal microbiota, effectively improving the efficiency of fecal microbiota transplantation for patients by medical personnel. Preferably, the syringe is a 50 mL syringe.

[0037] In one embodiment of this disclosure, two pairs of gloves may be placed within the second receiving cavity. A vacuum bag is provided outside the receiving box to ensure that the drug delivery device for fecal microbiota transplantation is kept in a sterile environment.

[0038] The preferred embodiments of this disclosure have been described in detail above with reference to the accompanying drawings. However, this disclosure is not limited to the specific details of the above embodiments. Within the scope of the technical concept of this disclosure, various simple modifications can be made to the technical solutions of this disclosure, and these simple modifications all fall within the protection scope of this disclosure.

[0039] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, this disclosure will not describe the various possible combinations separately.

[0040] Furthermore, various different embodiments of this disclosure can be combined in any way, as long as they do not violate the spirit of this disclosure, they should also be regarded as the content disclosed in this disclosure.

Claims

1. A drug delivery device for fecal microbiota transplantation, characterized in that, The device includes a drug delivery head (2) and an anal tube (1); The head (2) of the drug delivery device has a semi-ellipsoidal structure with an arc surface (10) and a closed surface (9). A fixed delivery tube (5) is inserted through the top of the arc surface (10), and the head of the fixed delivery tube (5) has an opening (4). A through hole is provided in the center of the closed surface (9) for the anal tube (1) to pass through. A sponge (7) is provided inside the fixed delivery tube (5) located in the head (2) of the drug delivery device. The head of the anal canal (1) is arc-shaped, and multiple three-way valve incisions are provided on the side wall of the head of the anal canal (1). An anal canal receiving bag (3) is provided on the outside of the anal canal (1). The fixed delivery pipe (5) and the sponge (7) are each independently cylindrical.

2. The drug delivery device according to claim 1, characterized in that, The number of three-way valve incisions is 4-6.

3. The drug delivery device according to claim 2, characterized in that, The tail of the anal tube (1) is a cylindrical flexible tube with an outer diameter of 3-8 mm and a length of 45-60 cm. Scales are provided on the tail of the anal tube (1).

4. The drug delivery device according to claim 3, characterized in that, The inner diameter of the fixed delivery pipe (5) is larger than the outer diameter of the tail of the anal tube (1).

5. The drug delivery device according to claim 1, characterized in that, The anal tube (1) is provided with a connector (6) at its tail end for connecting to a syringe.

6. The drug delivery device according to claim 5, characterized in that, The connector (6) is a tee connector.

7. The drug delivery device according to claim 1, characterized in that, The sponge (7) is provided with lubricating fluid.

8. The drug delivery device according to claim 1, characterized in that, The connecting end of the anal canal receiving bag (3) is connected to the arc-shaped surface (10).

9. The drug delivery device according to claim 1, characterized in that, A film bag (8) is provided on the outside of the fixed delivery tube (5) near the head (2) of the drug delivery device.

10. A dressing pack for fecal microbiota transplantation, characterized in that, The dressing kit includes a receiving box, which is provided with a first receiving cavity and a second receiving cavity; The first receiving cavity contains a drug delivery device for fecal microbiota transplantation as described in any one of claims 1-9; The second receiving cavity contains a syringe, a three-way connector, and a glove.

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