A solid phase extraction column device with multi-stage filtering structure

Abstract

The utility model relates to solid phase extraction technical field especially a kind of solid phase extraction overcolumn equipment with multistage filter structure. Including equipment frame, liquid storage tank, liquid transfer pump, solid phase extraction column, lifting assembly, first connecting pipe, sealing assembly and switching assembly;Control motor work, motor moves the movement of threaded block by double-end screw rod, threaded block moves along the support column and drives ring plate to move, so that both sides ring plate drives corresponding sleeve block to move towards the direction of moving away from rotary plate, then six threaded limit pieces that rotate in turn, so that both sides fixed block separates and thus six multistage filter structures are installed to the inside of U-shaped groove, and both sides fixed block are connected by threaded limit piece, realize the fixation to multistage filter structure, then control motor reversely rotates, double-end screw rod drives both sides ring plate to move towards the direction of multistage filter structure, connect multiple sleeve blocks to corresponding multistage filter structure, liquid is filtered by multistage filter structure.

Description

Technical Field

[0001] This utility model relates to the field of solid phase extraction technology, specifically a solid phase extraction column filter with a multi-stage filtration structure. Background Technology

[0002] In the field of sample pretreatment, solid phase extraction technology is an important separation and purification method, and is widely used in the detection of target compounds in food, agricultural and livestock products, environmental samples and biological samples.

[0003] For example, a solid-phase extraction (SPE) main device with authorization announcement number CN222871400U reduces manual operation steps during the SPE process, making the operation more convenient and reducing operator time. However, the SPE column equipment described in the document lacks a multi-stage filtration structure before the solution enters the SPE column, making it easy for larger particles from the solution to enter the column. This can cause blockage of the packing material inside the SPE column, affecting the detection results. Utility Model Content

[0004] The purpose of this invention is to solve the problems mentioned in the background art by proposing a solid phase extraction column device with a multi-stage filtration structure.

[0005] To achieve the above objectives, this utility model provides the following technical solution: Design a solid phase extraction column device with a multi-stage filtration structure, including a device frame, a liquid storage tank, a liquid pump, a solid phase extraction column, a lifting assembly, a first connecting pipe, a sealing assembly, and a switching assembly; The equipment frame has multiple solid-phase extraction columns in the middle. Each solid-phase extraction column has a sealing assembly attached to its upper part. The upper ends of the sealing assemblies are fixedly connected to the lifting end of the lifting assembly. A three-way connecting pipe is provided in the middle of the sealing assembly. The first connecting end of the three-way connecting pipe is fixedly connected to the sealing assembly and extends through the sealing assembly into the inner cavity of the solid-phase extraction column. The second connecting ends of the three-way connecting pipes are all connected to the first connecting pipe. The liquid inlet end of the first connecting pipe is connected to a switching assembly. The other side of the switching assembly is connected to the output end of the infusion pump. The input end of the infusion pump is connected to the storage tank.

[0006] Preferably, the third connecting ends of the plurality of three-way connecting pipes are all connected to the second connecting pipes via flexible hoses, and the air inlet end of the second connecting pipe is connected to the booster assembly.

[0007] Preferably, the lower side of the device frame is provided with a plurality of fixing components, which are located on the outside of the solid phase extraction column and are used to fix the solid phase extraction column.

[0008] Preferably, the lower end of the device frame is provided with multiple card holders, and the number of card holders is the same as the number of solid phase extraction columns, and the axis of the card holders on the same side is on the same axis as the axis of the solid phase extraction column.

[0009] Preferably, the switching assembly includes a support column, a bracket, a motor, a double-ended screw, a threaded block, a ring plate, a rotating plate, a multi-stage filtration structure, and a fixing mechanism; Both sides of the support column are fixedly connected to the bracket. A motor is fixedly installed at one end of the support column. The output end of the motor is fixedly connected to a double-ended screw. Both ends of the double-ended screw are rotatably connected to the support column. The outer walls of the double-ended screw are threadedly connected to threaded blocks on both sides. The outer walls of the threaded blocks are slidably connected to the support column. The outer ends of the threaded blocks are fixedly connected to a ring plate. The ring plate is sleeved on the outer wall of the support column, and the axis of the ring plate is on the same axis as the axis of the support column. A rotating plate is rotatably installed in the middle of the support column. Six sets of multi-stage filtration structures are provided in the middle of the rotating plate. Six sets of fixing mechanisms are provided on the outer side of the rotating plate.

[0010] Preferably, the rotating plate has six sets of U-shaped grooves in the middle, and the U-shaped grooves are distributed in a ring at equal angles. The distance between the arc end and the opening end of the U-shaped groove is the same as the maximum outer diameter of the multi-stage filtration structure. The U-shaped groove can fit into the multi-stage filtration structure. The ring plate is provided with six sets of sleeves on one side adjacent to the multi-stage filtration structure. The six sets of sleeves are distributed in a ring at equal angles. The inner wall of the sleeve is in contact with the multi-stage filtration structure. The inner wall of the sleeve is provided with a rubber ring to ensure the sealing performance between the sleeve and the multi-stage filtration structure. One of the sets of sleeves has a sleeve in the middle, and the axis of the sleeve is on the same axis as the axis of the set of sleeves. The outer wall of the sleeve is in contact with the multi-stage filtration structure, and a sealing ring is provided on the contact surface between the sleeve and the multi-stage filtration structure to ensure the sealing of the sleeve and the multi-stage filtration structure.

[0011] Preferably, the fixing mechanism includes a support block, a fixing block, and a threaded limiting component; The number of support blocks is six. The six support blocks are distributed in a ring at equal angles on the outside of the rotating plate, and each support block is set between the two U-shaped grooves. The two sides of the support block are respectively hinged to the two fixed blocks. The ends of the two support blocks away from the support blocks are threadedly connected to the threaded limiting parts. The two fixed blocks on the side adjacent to the multi-stage filter structure are in contact with the multi-stage filter structure.

[0012] Preferably, the side of the sleeve away from the sleeve block on one side is connected to the first connecting pipe, and the side of the sleeve away from the sleeve block on the other side is connected to the output end of the infusion pump.

[0013] This invention proposes a solid-phase extraction column filter with a multi-stage filtration structure. The advantages are as follows: The motor drives a threaded block via a double-headed screw. The threaded block moves along the support column, causing the ring plates to move. This causes the ring plates on both sides to move their corresponding sleeves away from the rotating plate. Subsequently, six threaded limiting members rotate sequentially, separating the fixed blocks on both sides and installing the six multi-stage filtration structures into the U-shaped groove. The fixed blocks on both sides are then connected via the threaded limiting members to fix the multi-stage filtration structure. The motor then rotates in the opposite direction, causing the double-headed screw to move the ring plates on both sides towards the multi-stage filtration structure, connecting multiple sleeves to their corresponding multi-stage filtration structures. The liquid is filtered through the multi-stage filtration structure, preventing larger impurities in the solution from entering the solid-phase extraction column and causing blockage of the packing material inside the column. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the structure of this utility model; Figure 2 This is a schematic diagram of the support column, motor, and double-ended screw of this utility model; Figure 3 for Figure 2 A schematic diagram of the structure of A in the middle; Figure 4 for Figure 2 A side view structural diagram.

[0015] In the diagram: 1. Equipment frame; 2. Lifting assembly; 3. Sealing assembly; 4. First connecting pipe; 5. Second connecting pipe; 6. Pressurization assembly; 7. Solid phase extraction column; 8. Fixing assembly; 9. Switching assembly; 901. Support column; 902. Bracket; 903. Motor; 904. Double-ended screw; 905. Threaded block; 906. Ring plate; 9061. Sleeve block; 9062. Sleeve; 907. Rotating plate; 9071. U-shaped groove; 908. Multi-stage filtration structure; 909. Fixing mechanism; 9091. Support block; 9092. Fixing block; 9093. Threaded limit component; 10. Card holder; 11. Infusion pump; 12. Storage tank. Detailed Implementation

[0016] The present invention will be further described below with reference to the accompanying drawings: See attached document Figure 1-4A solid-phase extraction column apparatus with a multi-stage filtration structure 908 includes an apparatus frame 1, a storage tank 12, a delivery pump 11, solid-phase extraction columns 7, a lifting assembly 2, a first connecting pipe 4, a sealing assembly 3, and a switching assembly 9. Multiple solid-phase extraction columns 7 are arranged in the middle of the apparatus frame 1. A sealing assembly 3 is fitted above each solid-phase extraction column 7. The upper ends of the multiple sealing assemblies 3 are fixedly connected to the lifting end of the lifting assembly 2. The lifting assembly 2 is preferably a hydraulic lifting assembly 2. The lifting end of the lifting assembly 2 can drive the multiple sealing assemblies 3 to move up and down. When the sealing assembly 3 moves downward, it seals the solid-phase extraction column 7. Gas is delivered to the inside of the second connecting pipe 5 by a booster pump 6. The second connecting pipe 5 then introduces the pressurized gas into the solid-phase extraction column through a three-way connecting pipe. Inside column 7, infusion pump 11 delivers liquid from storage tank 12 to the inside of first connecting pipe 4 via switching component 9. First connecting pipe 4 delivers liquid to the inside of solid phase extraction column 7, achieving automatic liquid addition. A three-way connecting pipe is provided in the middle of sealing component 3. The first connecting end of the three-way connecting pipe is fixedly connected to sealing component 3 and extends through sealing component 3 to the inner cavity of solid phase extraction column 7. The second connecting ends of multiple three-way connecting pipes are all connected to the first connecting pipe 4 via flexible hoses. The liquid inlet end of the first connecting pipe 4 is connected to switching component 9. The other side of switching component 9 is connected to the output end of infusion pump 11. The input end of infusion pump 11 is connected to storage tank 12. During solid phase extraction operation, personnel add different liquids to infusion tank 12 according to the operation procedure.

[0017] The third connecting ends of multiple three-way connecting pipes are all connected to the second connecting pipe 5 via flexible hoses. The air inlet end of the second connecting pipe 5 is connected to the pressurization component 6. Multiple fixing components 8 are provided on the lower side of the equipment frame 1, located on the outside of the solid-phase extraction column 7, for fixing the solid-phase extraction column 7. Multiple retaining seats 10 are provided at the lower end of the equipment frame 1, with the number of retaining seats 10 being the same as the number of solid-phase extraction columns 7. The axis of the retaining seats 10 on the same side is coaxial with the axis of the solid-phase extraction column 7. The fixing components 8 are used to limit the longitudinal position of the solid-phase extraction column 7, preventing it from moving with the lifting component 2.

[0018] The switching component 9 includes a support column 901, a bracket 902, a motor 903, a double-ended screw 904, a threaded block 905, a ring plate 906, a rotating plate 907, a multi-stage filtration structure 908, and a fixing mechanism 909. Both sides of the support column 901 are fixedly connected to the bracket 902. A motor 903 is fixedly mounted at one end of the support column 901. The output end of the motor 903 is fixedly connected to the double-ended screw 904. Both ends of the double-ended screw 904 are rotatably connected to the support column 901. The outer walls of the double-ended screw 904 are threadedly connected to the threaded blocks 905 on both sides. The outer walls of the threaded blocks 905 are slidably connected to the support column 901. The outer end is fixedly connected to the ring plate 906, which is sleeved on the outer wall of the support column 901. The axis of the ring plate 906 and the axis of the support column 901 are on the same axis. A rotating plate 907 is rotatably installed in the middle of the support column 901. Six sets of multi-stage filtration structures 908 are installed in the middle of the rotating plate 907. Six sets of fixing mechanisms 909 are installed on the outer side of the rotating plate 907. The double-ended screw 904 is rotatably connected to the support column 901 through bearings. The rotating plate 907 is rotatably connected to the support column 901 through bearings. The motor 903 drives the double-ended screw 904 to rotate. The threads on both sides of the double-ended screw 904 are in opposite directions, causing the threaded block 905 to move. In the opposite direction, the double-ended screw 904 drives the threaded blocks 905 on both sides to move. The threaded blocks 905 move along the support column 901, and the threaded blocks 905 drive the ring plate 906 to move, causing the ring plates 906 on both sides to drive the corresponding sleeve blocks 9061 to move away from the rotating plate 907. Subsequently, the six threaded limiting members 9093 rotate in sequence, causing the fixing blocks 9092 on both sides to separate, thereby installing the six multi-stage filter structures 908 into the interior of the U-shaped groove 9071. The fixing blocks 9092 on both sides are connected by the threaded limiting members to fix the multi-stage filter structure 908. Then, the motor 903 is controlled to rotate in the opposite direction, and the double-ended screw 904... The ring plates 906 on both sides are moved toward the multi-stage filtration structure 908, connecting multiple sleeves 9061 to the corresponding multi-stage filtration structures 908. One of the multi-stage filtration structures 908 is connected to the sleeve 9062. When the multi-stage filtration structure 908 at the current position becomes clogged after prolonged use, the control motor 903 causes the ring plates 906 on both sides to separate. The rotating plate 907 drives the next multi-stage filtration structure 908 to align with the sleeve 9062. Then, the ring plates 906 on both sides are merged, so that the infusion pump 11 delivers the liquid inside the storage tank 12 to the multi-stage filtration structure for filtration and then delivers it to the solid phase extraction column 7.

[0019] The rotating plate 907 has six sets of U-shaped grooves 9071 in the middle, and the U-shaped grooves 9071 are arranged in a ring at equal angles. The distance between the arc end and the opening end of the U-shaped groove 9071 is the same as the maximum outer diameter of the multi-stage filter structure 908. The U-shaped grooves 9071 can fit snugly against the multi-stage filter structure 908. The ring plate 906 has six sets of sleeve blocks 9061 on one side adjacent to the multi-stage filter structure 908. The six sets of sleeve blocks 9061 are arranged in a ring at equal angles. The inner wall of the sleeve blocks 9061 fits snugly against the multi-stage filter structure 908. The sleeve 9061 is fitted with a rubber ring on its inner wall to ensure the sealing performance between the sleeve 9061 and the multi-stage filter structure 908. A sleeve 9062 is provided in the middle of one set of sleeves 9061. The axis of the sleeve 9062 is on the same axis as the axis of the set of sleeves 9061. The outer wall of the sleeve 9062 is fitted with the multi-stage filter structure 908. A sealing ring is provided on the contact surface between the sleeve 9062 and the multi-stage filter structure 908 to ensure the sealing performance between the sleeve 9062 and the multi-stage filter structure 908.

[0020] The fixing mechanism 909 includes a support block 9091, a fixing block 9092, and a threaded limiting member 9093. There are six support blocks 9091, which are distributed in a ring at equal angles on the outside of the rotating plate 907. Each support block 9091 is located between the two U-shaped grooves 9071. The two sides of the support block 9091 are hinged to the two fixing blocks 9092. The ends of the two support blocks 9091 that are away from the support block 9091 are threaded to the threaded limiting member 9093. The two fixing blocks 9092 on the side adjacent to the multi-stage filtration structure 908 are in contact with the multi-stage filtration structure 908. The side of the sleeve 9062 on one side that is away from the sleeve block 9061 is connected to the first connecting pipe 4. The side of the sleeve 6092 on the other side that is away from the sleeve block 9061 is connected to the output end of the infusion pump 11. The filtration structure of the multi-stage filtration structure 908 from the side adjacent to the infusion pump 11 to the first connecting pipe 4 has a gradient decrease.

[0021] Specifically, the control motor 903 operates, driving the double-ended screw 904 to rotate. The threads on both sides of the double-ended screw 904 are in opposite directions, causing the threaded blocks 905 to move in opposite directions. The double-ended screw 904 drives the threaded blocks 905 on both sides to move, and the threaded blocks 905 move along the support column 901. The threaded blocks 905 drive the ring plate 906 to move, causing the ring plates 906 on both sides to move their corresponding sleeves 9061 away from the rotating plate 907. Subsequently, the six threaded limiting members 9093 rotate sequentially, causing the fixing blocks 9092 on both sides to separate, thereby separating the six multi-stage filter structures 90... 8 is installed inside the U-shaped groove 9071, and the fixing blocks 9092 on both sides are connected by threaded limiting parts to fix the multi-stage filtration structure 908. Then, the motor 903 is controlled to rotate in the reverse direction, and the double-headed screw 904 drives the ring plates 906 on both sides to move towards the multi-stage filtration structure 908, connecting multiple sleeve blocks 9061 to the corresponding multi-stage filtration structures 908, and placing multiple solid phase extraction columns 7 between the fixing components 8 to fix them in the equipment frame 1. When the sealing component 3 moves downward, it seals the solid phase extraction columns 7, and the gas is delivered to the booster pump 6. Inside the second connecting pipe 5, pressurized gas is introduced into the solid-phase extraction column 7 via a three-way connecting pipe. The infusion pump 11 delivers liquid from the storage tank 12 to the first connecting pipe 4 via the switching component 9, enabling automatic liquid addition. Gas is delivered to the second connecting pipe 5 via the booster pump 6, and pressurized gas is introduced into the solid-phase extraction column 7 via the three-way connecting pipe, accelerating the liquid's outflow from the column. The liquid is then filtered through a multi-stage filtration structure 908 to prevent... Larger impurities in the solution can enter the solid-phase extraction column 7, causing blockage of the packing material inside. When the multi-stage filtration structure 908 at the current position becomes clogged due to prolonged use, the control motor 903 separates the two side ring plates 906. The rotating plate 907 drives the next multi-stage filtration structure 908 to align with the sleeve 9062. Subsequently, the two side ring plates 906 are merged, allowing the infusion pump 11 to deliver the liquid from the storage tank 12 to the multi-stage filtration structure for filtration. This makes the replacement of the multi-stage filtration structure 908 more convenient, shortens the replacement time, and improves work efficiency.

[0022] Although the present invention has been illustrated and described with reference to preferred embodiments, those skilled in the art should understand that various changes in form and detail are possible within the scope of the claims.

Claims

1. A solid-phase extraction column filter with a multi-stage filtration structure, characterized in that: It includes an equipment rack, a liquid storage tank, an infusion pump, a solid phase extraction column, a lifting assembly, a first connecting pipe, a sealing assembly, and a switching assembly; The equipment frame has multiple solid-phase extraction columns in the middle. Each solid-phase extraction column has a sealing assembly attached to its upper part. The upper ends of the sealing assemblies are fixedly connected to the lifting end of the lifting assembly. A three-way connecting pipe is provided in the middle of the sealing assembly. The first connecting end of the three-way connecting pipe is fixedly connected to the sealing assembly and extends through the sealing assembly into the inner cavity of the solid-phase extraction column. The second connecting ends of the three-way connecting pipes are all connected to the first connecting pipe. The liquid inlet end of the first connecting pipe is connected to a switching assembly. The other side of the switching assembly is connected to the output end of the infusion pump. The input end of the infusion pump is connected to the storage tank.

2. The solid-phase extraction column apparatus with a multi-stage filtration structure according to claim 1, characterized in that: The third connection ends of the plurality of three-way connecting pipes are all connected to the second connecting pipes via flexible hoses, and the air inlet end of the second connecting pipes is connected to the booster assembly.

3. A solid-phase extraction column apparatus with a multi-stage filtration structure according to claim 1, characterized in that: The lower side of the equipment frame is provided with multiple fixing components, which are located on the outside of the solid phase extraction column and are used to fix the solid phase extraction column.

4. A solid-phase extraction column filter with a multi-stage filtration structure according to claim 1, characterized in that: The lower end of the equipment rack is provided with multiple card holders, and the number of card holders is the same as the number of solid phase extraction columns. The axis of the card holders on the same side is on the same axis as the axis of the solid phase extraction column.

5. A solid-phase extraction column filter with a multi-stage filtration structure according to claim 1, characterized in that: The switching assembly includes a support column, a bracket, a motor, a double-headed screw, a threaded block, a ring plate, a rotating plate, a multi-stage filtration structure, and a fixing mechanism. Both sides of the support column are fixedly connected to the bracket. A motor is fixedly installed at one end of the support column. The output end of the motor is fixedly connected to a double-ended screw. Both ends of the double-ended screw are rotatably connected to the support column. The outer walls of the double-ended screw are threadedly connected to threaded blocks on both sides. The outer walls of the threaded blocks are slidably connected to the support column. The outer ends of the threaded blocks are fixedly connected to a ring plate. The ring plate is sleeved on the outer wall of the support column, and the axis of the ring plate is on the same axis as the axis of the support column. A rotating plate is rotatably installed in the middle of the support column. Six sets of multi-stage filtration structures are provided in the middle of the rotating plate. Six sets of fixing mechanisms are provided on the outer side of the rotating plate.

6. A solid-phase extraction column apparatus with a multi-stage filtration structure according to claim 5, characterized in that: The rotating plate has six sets of U-shaped grooves in the middle, and the U-shaped grooves are distributed in a ring at equal angles. The distance between the arc end and the opening end of the U-shaped groove is the same as the maximum outer diameter of the multi-stage filtration structure. The U-shaped grooves can fit into the multi-stage filtration structure. The ring plate is provided with six sets of sleeves on one side adjacent to the multi-stage filtration structure. The six sets of sleeves are distributed in a ring at equal angles. The inner wall of the sleeve is in contact with the multi-stage filtration structure. The inner wall of the sleeve is provided with a rubber ring to ensure the sealing performance between the sleeve and the multi-stage filtration structure. One of the sets of sleeves has a sleeve in the middle, and the axis of the sleeve is on the same axis as the axis of the set of sleeves. The outer wall of the sleeve is in contact with the multi-stage filtration structure, and a sealing ring is provided on the contact surface between the sleeve and the multi-stage filtration structure to ensure the sealing of the sleeve and the multi-stage filtration structure.

7. A solid-phase extraction column apparatus with a multi-stage filtration structure according to claim 5, characterized in that: The fixing mechanism includes a support block, a fixing block, and a threaded limiting component; The number of support blocks is six. The six support blocks are distributed in a ring at equal angles on the outside of the rotating plate, and each support block is set between the two U-shaped grooves. The two sides of the support block are respectively hinged to the two fixed blocks. The ends of the two support blocks away from the support blocks are threadedly connected to the threaded limiting parts. The two fixed blocks on the side adjacent to the multi-stage filter structure are in contact with the multi-stage filter structure.

8. A solid-phase extraction column apparatus with a multi-stage filtration structure according to claim 6, characterized in that: One side of the sleeve, away from the sleeve block, is connected to the first connecting pipe, and the other side of the sleeve, away from the sleeve block, is connected to the output end of the infusion pump.

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