Chromatography tank for extracting skin care raw material artemisinin

Abstract

The utility model discloses skin care product raw material artemisinin extraction uses chromatography tank in artemisinin extraction technical field, including chromatography tank body, cloth liquid mechanism, sieve plate and vibration mechanism. Chromatography tank body is equipped with the temperature control chamber of liquid inlet pipe and liquid outlet pipe, cloth liquid mechanism sets up in the inside of upper end cover, contains multistage and covers umbrella -shaped cloth liquid tray and uniform distribution microporous plate in proper order, constitutes multistage buffer and even flow channel, sieve plate is located in the inner wall of jar body for supporting filler, the core innovation of vibration mechanism is, its utilize temperature control system circulation medium flow into the power that liquid inlet pipe produced, through drive part drives rotating rod and knocking rod periodicity knock sieve plate. The utility model discloses through pure mechanical structure has realized the automatic vibration of filler and the auxiliary unloading of filling, effectively eliminated the filling bubble and fault, solved the difficult problem of viscous filler unloading, ensured the uniformity of liquid distribution simultaneously, has the remarkable advantages such as energy -conserving high efficiency, high reliability, maintenance convenient.

Description

Technical Field

[0001] This utility model relates to the field of artemisinin extraction technology, specifically a chromatography tank for extracting artemisinin, a raw material for skin care products. Background Technology

[0002] Column chromatography is a crucial step in the separation and purification of artemisinin, and the performance of the equipment directly affects the purity and yield of the product. Currently, there are significant shortcomings in the packing and unloading processes of chromatography tanks used for artemisinin extraction. During packing, the process relies heavily on natural sedimentation due to gravity, which easily generates bubbles and breaks in the packing, affecting the separation effect. During unloading, viscous waste packing material tends to adhere to the tank walls and sieve plates, making it difficult to completely remove and causing inconvenience in cleaning.

[0003] To address the aforementioned issues, existing technologies employ external electric or pneumatic vibrators to assist in loading and unloading. For example, a vibrating motor is installed on the outer wall to promote packing compaction or dislodgement. However, such solutions have significant drawbacks: First, they add an extra power source and control unit, increasing equipment manufacturing costs and energy consumption. Second, vibrating motors operating in long-term humid environments pose a risk of circuit insulation and sealing failure, reducing reliability and making maintenance inconvenient. Third, external vibration is mostly intermittent and manual, failing to achieve automatic and continuous optimization during chromatography. Furthermore, chromatography often requires maintaining a specific temperature; existing equipment generally features an insulated jacket with circulating media, but this structure has a single function, only used for heat exchange, and its energy is not fully utilized. Simultaneously, the liquid distribution system at the top of the chromatography tank, such as a simple distribution plate, still carries the risk of uneven distribution or easy clogging.

[0004] To address the aforementioned issues, this application provides a chromatography tank for extracting artemisinin, a raw material for skincare products. Utility Model Content

[0005] The purpose of this utility model is to solve the problems mentioned in the background art by providing a chromatography tank for extracting artemisinin, a raw material for skin care products.

[0006] To achieve the above objectives, this utility model specifically adopts the following technical solution: A chromatography vessel for extracting artemisinin, a raw material for skincare products, includes the vessel body, a liquid distribution mechanism, a sieve plate, and a vibration mechanism, wherein: The chromatography tank body includes a tank body, an upper end cover and a lower end cover. The upper end cover is provided with a feed pipe and the lower end cover is provided with a discharge pipe. The tank body is cylindrical and has an annular temperature control cavity inside. The outer side of the tank body is provided with a liquid inlet pipe and a liquid outlet pipe that communicate with the temperature control cavity. The liquid distribution mechanism is installed inside the upper end cover and corresponds to the feed pipe; The sieve plate is installed on the inner wall of the tank and is used to support the packing material; The vibration mechanism is installed on the tank body. The vibration mechanism uses the water flow inside the liquid inlet pipe as power and can periodically tap the bottom of the sieve plate.

[0007] Furthermore, the bottom end of the feed pipe extends into the interior of the upper cover. The liquid distribution mechanism includes several umbrella-shaped liquid distribution trays of different sizes, which are arranged in descending order of size, with the largest tray located on the outermost side and the smallest tray on the innermost side. A liquid distribution channel is formed between two adjacent trays. A liquid distribution pipe is fixed to the top of each tray, and the diameters of the pipes are arranged in descending order of size, with the pipe with the largest diameter installed on the largest tray and the pipe with the smallest diameter installed on the smallest tray. The trays are fixed by a fixing rod.

[0008] Furthermore, a uniformly distributed microporous plate located directly below several umbrella-shaped liquid distribution trays is installed on the inner wall of the upper end cover.

[0009] Furthermore, the vibration mechanism includes a rotating rod horizontally rotatably mounted on the inner wall of the tank, a plurality of mounting sleeves arranged in an array fixed on the rotating rod, a striking rod movably inserted into one end of the mounting sleeve, a spring connecting one end of the striking rod to the inner wall of the mounting sleeve, one end of the striking rod corresponding to the center of the bottom of the sieve plate, and the vibration mechanism also includes a driving part for driving the rotating rod to rotate.

[0010] Furthermore, the drive unit includes a circular mounting box fixedly connected to the middle of the liquid inlet pipe. A mounting rod is rotatably mounted on the central axis of the circular mounting box. Several blades arranged in an array are fixed on the mounting rod. One end of the rotating rod movably passes through the tank body and is fixed to one end of the mounting rod.

[0011] Furthermore, a rolling ball is connected to the end of the striking rod corresponding to the sieve plate.

[0012] Furthermore, flanges are fixed to both ends of the tank body, the outer side of the upper end cover, and the outer side of the lower end cover. The two flanges at both ends of the tank body are respectively fixedly connected to the flanges on the outer side of the upper end cover and the lower end cover by bolts.

[0013] Furthermore, an observation port is constructed through the tank body, and a glass window is fixed to the observation port.

[0014] Compared with the prior art, the beneficial effects of this utility model are: 1. This solution utilizes the flow of the circulating medium in the control system as a power source. Through the mechanical linkage between the blades of the drive unit and the vibration mechanism, the striking rod can periodically and automatically strike the sieve plate. This vibration can effectively promote the compact packing during packing, eliminate air bubbles and discontinuities, and ensure the uniformity and stability of the chromatography bed, thereby improving separation purity and efficiency. During unloading, the continuous vibration can effectively break the adsorption force between the packing and the tank wall and sieve plate, allowing viscous waste to be discharged smoothly and thoroughly, greatly reducing labor intensity and facilitating subsequent cleaning.

[0015] 2. The vibration function of this solution does not rely on external power or air source or other additional power. It only utilizes the kinetic energy of the circulating medium that must exist in the process flow, realizing the secondary utilization of energy and having a significant energy saving effect. At the same time, the entire vibration mechanism is a pure mechanical transmission, eliminating the need for electrical control components and their complex sealing structure, fundamentally eliminating potential safety hazards such as circuit insulation and leakage in humid environments. The equipment has high operational reliability and low maintenance cost.

[0016] 3. This solution employs a multi-stage umbrella-shaped liquid distribution mechanism, consisting of progressively smaller, overlapping liquid distribution discs, combined with a uniformly distributed microporous plate. This creates a multi-stage buffering, diffusion, and uniformly distributed flow path. This structure effectively disperses and uniformly distributes the liquid flow, avoiding "channeling" and "wall flow" phenomena, ensuring full contact with the packing material, and improving separation efficiency. Furthermore, its flow channel design is less prone to clogging compared to microporous straight-through structures, making it particularly suitable for artemisinin crude extract containing trace particles.

[0017] 4. In this design, the tank body, upper end cover, and lower end cover are connected by flanges and bolts, forming a modular quick-assembly structure. This design makes disassembly, cleaning, and packing and replacement of the equipment extremely convenient, effectively preventing cross-contamination between different batches of materials. Furthermore, the observation port and glass window allow operators to monitor the packing status and chromatography process inside the tank in real time and intuitively, facilitating timely adjustments to process parameters. Attached Figure Description

[0018] Figure 1 This is a three-dimensional structural diagram of the present invention; Figure 2 This utility model Figure 1 A three-dimensional sectional view; Figure 3 This utility model Figure 2 An enlarged view of structure A in the middle; Figure 4 This utility model Figure 2 An enlarged view of the B-structure; Figure 5 This utility model Figure 1 A three-dimensional sectional view from another direction; Figure 6 This utility model Figure 2 An enlarged view of the middle section of the structure.

[0019] In the diagram: 1. Chromatography tank body; 11. Tank body; 111. Observation port; 112. Glass window; 12. Upper end cover; 13. Lower end cover; 14. Feed pipe; 15. Discharge pipe; 16. Temperature control chamber; 17. Liquid inlet pipe; 18. Liquid outlet pipe; 19. Flange; 2. Liquid distribution mechanism; 21. Umbrella-shaped liquid distribution tray; 22. Liquid distribution channel; 23. Liquid distribution pipe; 24. Fixing rod; 25. Uniformly distributed microporous plate; 3. Sieve plate; 4. Vibration mechanism; 41. Rotating rod; 42. Mounting sleeve; 43. Striking rod; 431. Rolling ball; 44. Spring; 45. Drive unit; 451. Circular mounting box; 452. Mounting rod; 453. Blade. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings.

[0021] This application provides a chromatography tank for extracting artemisinin, a raw material for skincare products. Currently, chromatography tanks for artemisinin extraction have significant shortcomings in the packing and unloading processes. During packing, they rely heavily on natural gravity settling, which easily generates bubbles and discontinuities, affecting separation efficiency. During unloading, viscous waste packing material easily adheres to the tank walls and sieve plates, making complete removal difficult and cleaning inconvenient. The application provides the following technical solution, which will be discussed below in conjunction with… Figures 1-6 Please provide a detailed explanation: The present invention discloses a chromatography tank for extracting artemisinin, a raw material for skin care products, comprising a chromatography tank body 1, a liquid distribution mechanism 2, a sieve plate 3, and a vibration mechanism 4.

[0022] The chromatography tank body 1 serves as the core supporting structure and is made of corrosion-resistant 316 stainless steel. The chromatography tank body 1 includes a tank body 11, an upper end cover 12, and a lower end cover 13. The upper end cover 12 is provided with a feed pipe 14 for receiving the crude artemisinin extract, and the lower end cover 13 is provided with a discharge pipe 15 for collecting the purified liquid. The tank body 11 is cylindrical and has an annular temperature control chamber 16 inside. The outer side of the tank body 11 is provided with an inlet pipe 17 and an outlet pipe 18 that are connected to the temperature control chamber 16 and can be connected to a constant temperature circulating water bath. This is the power source and temperature control basis of the vibration mechanism 4. The liquid distribution mechanism 2 is installed inside the upper end cover 12 and corresponds to the feed pipe 14. The extract enters the liquid distribution mechanism 2 inside the upper end cover 12 through the feed pipe 14, so that the extract is evenly covered on the packing surface on the sieve plate 3, avoiding bubbles or discontinuity due to uneven liquid inlet, and improving the separation effect. The sieve plate 3 is installed on the inner wall of the tank body 11 and is used to support the packing. The vibration mechanism 4 is installed on the tank body 11. The vibration mechanism 4 uses the water flow inside the liquid inlet pipe 17 as power and can periodically knock the bottom of the sieve plate 3. This vibration can effectively promote the compaction of the packing, eliminate air bubbles and discontinuities, and form a uniform chromatography bed, thereby significantly improving the separation and purification effect of artemisinin. During unloading, the continuous knocking vibration can effectively break the adsorption of viscous waste packing to the sieve plate 3 and the tank wall, and help it to be discharged smoothly and thoroughly from the discharge pipe 15, which greatly simplifies the cleaning and maintenance work.

[0023] For details, please refer to Figure 2 and Figure 3 The bottom end of the feed pipe 14 extends into the interior of the upper cover 12. The liquid distribution mechanism 2 includes several umbrella-shaped liquid distribution plates 21 of varying sizes. The umbrella-shaped liquid distribution plates 21 are made of corrosion-resistant 304 stainless steel. The several umbrella-shaped liquid distribution plates 21 are arranged in descending order of size, with the largest umbrella-shaped liquid distribution plate 21 located on the outermost side and the smallest umbrella-shaped liquid distribution plate 21 located on the innermost side. This unique spatial layout forms a progressively diffusing liquid distribution surface, which can adapt to different liquid flow rates and ensure that the initial impact energy of the liquid is absorbed. The liquid is absorbed step by step and effectively. A liquid distribution channel 22 is formed between two adjacent umbrella-shaped liquid distribution trays 21. A liquid distribution pipe 23 is fixed on the top of several umbrella-shaped liquid distribution trays 21. The liquid distribution pipe 23 is made of corrosion-resistant metal 304 stainless steel. The diameter of several liquid distribution pipes 23 is arranged from large to small, and the liquid distribution pipe 23 with the largest diameter is installed on the largest umbrella-shaped liquid distribution tray 21, and the liquid distribution pipe 23 with the smallest diameter is installed on the smallest umbrella-shaped liquid distribution tray 21. Several umbrella-shaped liquid distribution trays 21 are fixed by fixing rods 24. During operation, the extract flows into each distribution pipe 23 after entering the feed pipe 14, and then into the corresponding umbrella-shaped distribution plate 21. It is then evenly distributed out through the distribution channel 22, thereby achieving uniform distribution of the extract on the packing surface of the sieve plate 3, avoiding bubbles or discontinuity caused by uneven liquid inflow, and effectively improving the separation effect of artemisinin. The beneficial effect of this structural design is that, through the cooperation of the multi-layer umbrella-shaped liquid distribution plate 21 and the liquid distribution channel 22, the liquid distribution area of ​​the extract is greatly increased, allowing the extract to fully contact the packing material and improving the separation efficiency. At the same time, the 304 stainless steel umbrella-shaped liquid distribution plate 21 is resistant to chemical corrosion, and the 304 stainless steel liquid distribution pipe 23 is strong and not easy to rust. The combination of the two ensures the long-term stable operation of the liquid distribution mechanism 2, meeting the requirements of cleanliness and durability of the equipment for the extraction of artemisinin, a raw material for skin care products.

[0024] The inner wall of the upper cover 12 is equipped with a uniformly distributed microporous plate 25 located directly below several umbrella-shaped liquid distribution plates 21. The uniformly distributed microporous plate 25 is made of 316L stainless steel. During operation, the extract after being dispersed by the umbrella-shaped liquid distribution plates 21 and the liquid distribution channel 22 will fall onto the uniformly distributed microporous plate 25, and be homogenized again through its dense micropores to form a finer and more uniform liquid flow, which then covers the packing surface on the sieve plate 3. The beneficial effects of this structure are that the uniformly distributed microporous plate 25 made of 316L stainless steel has excellent corrosion resistance and mechanical strength, and can withstand the impact of the extract for a long time; through the secondary homogenization effect, the flow difference of the extract is further eliminated, avoiding the packing material from being discontinuous due to excessive local liquid flow, ensuring the stability of the artemisinin separation process, and ultimately improving the extraction purity to meet the requirements of skin care raw materials for high-purity artemisinin.

[0025] For further details, please refer to Figure 2 , Figure 4 , Figure 5 and Figure 6 The vibration mechanism 4 includes a rotating rod 41 that is horizontally rotatably mounted on the inner wall of the tank 11. Several mounting sleeves 42 arranged in an array are fixed on the rotating rod 41. A striking rod 43 is movably inserted into one end of the mounting sleeve 42. A spring 44 is connected between one end of the striking rod 43 and the inner wall of the mounting sleeve 42. One end of the striking rod 43 corresponds to the center of the bottom of the sieve plate 3. The vibration mechanism 4 also includes a driving part 45 for driving the rotating rod 41 to rotate, thus forming a mechanical system that can generate high-frequency, intermittent striking action. The drive unit 45 includes a circular mounting box 451 fixedly connected to the middle of the inlet pipe 17. A mounting rod 452 is rotatably mounted on the central axis of the circular mounting box 451. Several blades 453 arranged in an array are fixed on the mounting rod 452. One end of the rotating rod 41 movably passes through the tank 11 and is fixed to one end of the mounting rod 452. When the operating equipment performs temperature control, the circulating medium flows through the inlet pipe 17 into the circular mounting box 451, impacts the blades 453 and drives the mounting rod 452 to rotate. The rotation of the mounting rod 452 drives the rotating rod 41 to rotate. The rotating rod 41 drives the mounting sleeve 42 on it to rotate synchronously. The ball 431 at one end of the striking rod 43 abuts against the bottom of the screen plate 3, and the screen plate 3 vibrates.

[0026] The striking rod 43 has a ball connected to a rolling ball 431 at the end corresponding to the sieve plate 3. The rolling ball 431 impacts the sieve plate 3 to generate high-frequency micro-amplitude vibration. This vibration can be effectively transmitted to the entire packing layer, promoting the compaction of the packing and eliminating air bubbles during filling. During unloading, it can effectively break the adhesion between the packing and the sieve plate 3 and the tank wall, assisting in unloading. At the same time, the rolling ball 431 connected to the ball can convert sliding friction into rolling friction, greatly reducing the wear of the contact point and allowing a certain angular deviation, thus improving the long-term operational reliability and service life of the mechanism.

[0027] The beneficial effects of this structure are that it uses the water flow in the inlet pipe 17 as a power source to drive the vibration mechanism 4, eliminating the need for an additional power source and saving energy. At the same time, it can loosen the viscous waste filler from the sieve plate 3 and the inner wall of the tank 11, solving the problem of waste filler adhesion and inconvenient cleaning during unloading of traditional chromatography tanks, improving unloading efficiency and equipment maintenance convenience, and meeting the production needs of artemisinin extraction, a raw material for skin care products.

[0028] Furthermore, please refer to Figure 1 , Figure 2 and Figure 5 Flanges 19 are fixed to both ends of the tank body 11, the outer side of the upper end cover 12, and the outer side of the lower end cover 13. The two flanges 19 at both ends of the tank body 11 are fixedly connected to the flanges 19 on the outer side of the upper end cover 12 and the lower end cover 13 respectively by bolts.

[0029] The tank body 11 has a through structure with an observation port 111, and a glass window 112 is fixed on the observation port 111.

[0030] During operation, if maintenance or packing replacement is required inside the chromatography tank, the bolts on the flange 19 can be unscrewed to separate the upper end cover 12 and the lower end cover 13 from the tank body 11, making the operation convenient. During the extraction process, the operator can observe the status of the packing, the liquid level, and the separation process in real time through the glass window 112 on the observation port 111, so as to adjust the operating parameters in a timely manner.

[0031] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A chromatography tank for extracting artemisinin, a raw material for skincare products, comprising a chromatography tank body (1), a liquid distribution mechanism (2), a sieve plate (3), and a vibration mechanism (4), characterized in that, in: The chromatography tank body (1) includes a tank body (11), an upper end cover (12) and a lower end cover (13). The upper end cover (12) is provided with a feed pipe (14), and the lower end cover (13) is provided with a discharge pipe (15). The tank body (11) is cylindrical and has an annular temperature control cavity (16) inside. The outer side of the tank body (11) is provided with a liquid inlet pipe (17) and a liquid outlet pipe (18) that are connected to the temperature control cavity (16). The liquid distribution mechanism (2) is installed inside the upper end cover (12) and corresponds to the feed pipe (14); The sieve plate (3) is installed on the inner wall of the tank body (11) and is used to support the packing. The vibration mechanism (4) is installed on the tank (11). The vibration mechanism (4) uses the water flow inside the liquid inlet pipe (17) as power and can periodically strike the bottom of the sieve plate (3).

2. The chromatography tank for extracting artemisinin, a raw material for skincare products, according to claim 1, is characterized in that: The bottom end of the feed pipe (14) extends into the interior of the upper cover (12). The liquid distribution mechanism (2) includes several umbrella-shaped liquid distribution plates (21) of different sizes. The several umbrella-shaped liquid distribution plates (21) are arranged in descending order of size, with the largest umbrella-shaped liquid distribution plate (21) located on the outermost side and the smallest umbrella-shaped liquid distribution plate (21) located on the innermost side. A liquid distribution channel (22) is formed between two adjacent umbrella-shaped liquid distribution plates (21). A liquid distribution pipe (23) is fixed to the top of each of the several umbrella-shaped liquid distribution plates (21). The diameters of the several liquid distribution pipes (23) are arranged in descending order of size, with the liquid distribution pipe (23) of the largest diameter installed on the largest umbrella-shaped liquid distribution plate (21) and the liquid distribution pipe (23) of the smallest diameter installed on the smallest umbrella-shaped liquid distribution plate (21). The several umbrella-shaped liquid distribution plates (21) are fixed by a fixing rod (24).

3. The chromatography tank for extracting artemisinin, a raw material for skincare products, according to claim 2, is characterized in that: The inner wall of the upper end cover (12) is equipped with a uniformly distributed microporous plate (25) located directly below several umbrella-shaped liquid distribution trays (21).

4. The chromatography tank for extracting artemisinin, a raw material for skincare products, according to claim 1, is characterized in that: The vibration mechanism (4) includes a rotating rod (41) that is horizontally rotatably mounted on the inner wall of the tank (11). Several mounting sleeves (42) arranged in an array are fixed on the rotating rod (41). A striking rod (43) is movably inserted into one end of the mounting sleeve (42). A spring (44) is connected between one end of the striking rod (43) and the inner wall of the mounting sleeve (42). One end of the striking rod (43) corresponds to the center of the bottom of the sieve plate (3). The vibration mechanism (4) also includes a driving part (45) for driving the rotating rod (41) to rotate.

5. The chromatography tank for extracting artemisinin, a raw material for skincare products, according to claim 4, is characterized in that: The drive unit (45) includes a circular mounting box (451) fixedly connected to the middle of the liquid inlet pipe (17). A mounting rod (452) is rotatably mounted on the central axis of the circular mounting box (451). Several blades (453) are fixed on the mounting rod (452) in an array. One end of the rotating rod (41) movably passes through the tank body (11) and is fixed to one end of the mounting rod (452).

6. The chromatography tank for extracting artemisinin, a raw material for skincare products, according to claim 4, is characterized in that: The striking rod (43) has a ball (431) connected to the end of the sieve plate (3) corresponding to the end of the sieve plate (3).

7. The chromatography tank for extracting artemisinin, a raw material for skincare products, according to claim 1, is characterized in that: Flanges (19) are fixed to both ends of the tank body (11), the outer side of the upper end cover (12), and the outer side of the lower end cover (13). The two flanges (19) at both ends of the tank body (11) are respectively fixedly connected to the flanges (19) on the outer side of the upper end cover (12) and the lower end cover (13) by bolts.

8. The chromatography vessel for extracting artemisinin, a raw material for skincare products, according to claim 1, is characterized in that: The tank (11) has an observation port (111) through it, and a glass window (112) is fixed on the observation port (111).

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