A peripheral blood and bone marrow cell culture cycle timer

Abstract

The utility model discloses a kind of for peripheral blood and bone marrow cell culture cycle timing tracker, it is related to cell culture technical field, including incubator body, the front side of the incubator body is rotatably connected with box door, the outside of the incubator body is movably installed with control panel, the left side of the incubator body is fixedly connected with several vertical distribution alarm lamp, the inside of the incubator body is movably sleeved with several vertical distribution placement mechanism, the placement mechanism includes placement drawer box, the inside of the placement drawer box is movably sleeved with placement rack.The utility model said a kind of for peripheral blood and bone marrow cell culture cycle timing tracker, each culture tube is monitored by timing module, so that only in the placement drawer box corresponding to the alarm lamp of the culture tube at the set time is placed, and then standard placement rack is placed operation, cooperate control panel and alarm lamp, and the yield of culture is greatly improved.

Description

Technical Field

[0001] This utility model relates to the field of cell culture technology, and in particular to a timed tracker for the culture cycle of peripheral blood and bone marrow cells. Background Technology

[0002] Peripheral blood and bone marrow chromosome preparation is a core technology in cytogenetics, hematology, oncology research, and clinical diagnosis. It involves obtaining high-quality chromosomes for karyotype analysis to detect chromosomal numerical abnormalities (such as trisomy and monosomy) and structural abnormalities (such as translocation, deletion, and duplication).

[0003] The existing technology has the following problems: Existing cultivation methods place the culture tubes in an incubator. Due to the different batches being cultivated, staff may place the culture tubes haphazardly during daily operations, which could result in some batches of culture tubes being harvested prematurely before the cultivation period, leading to fewer cell division phases and cultivation failure. Utility Model Content

[0004] The main purpose of this invention is to provide a timed tracker for the culture cycle of peripheral blood and bone marrow cells, which can effectively solve the problem of early harvesting due to different batches.

[0005] To achieve the above objectives, the technical solution adopted by this utility model is as follows: A timed tracker for the culture cycle of peripheral blood and bone marrow cells includes a culture chamber body, a door rotatably connected to the front side of the culture chamber body, a control panel movably mounted on the outer side of the culture chamber body, a number of vertically distributed alarm lights fixedly connected to the left side of the culture chamber body, and a number of vertically distributed mounting mechanisms movably sleeved on the inner side of the culture chamber body. The placement mechanism includes a placement drawer box, with a placement frame movably sleeved on the inner side of the placement drawer box. The upper side of the placement frame has several rectangular placement holes, and several ring-shaped fixing components are movably sleeved on the inner side of each of the placement holes. Two damping components are fixedly connected to the left and right sides of the placement drawer box.

[0006] Preferably, the lower side of the mounting frame has several annularly distributed mounting slots.

[0007] Preferably, the upper side of the mounting frame is provided with several rectangularly distributed pick-and-place slots.

[0008] Preferably, the inner side of the drawer box is movably fitted with a partition plate.

[0009] Preferably, the fixing component includes a limiting rod, the upper and lower ends of which are fixedly connected to the inner side of the mounting frame. Two slides distributed vertically are movably sleeved on the outer side of the limiting rod. A push rod is rotatably connected to the side of each slide near the mounting hole. A clamping plate is rotatably connected to the side of the push rod away from the limiting rod. The outer side of the clamping plate, away from the limiting rod, is movably sleeved on the inner side of the mounting hole. Two springs distributed vertically are movably sleeved on the outer side of the limiting rod, with the springs located on the side of the two slides that are far apart from each other.

[0010] Preferably, the clamping plate is made of a highly wear-resistant material.

[0011] Preferably, the damping assembly includes a vent pipe, the outer side of which is fixedly connected to the left and right inner sides of the incubator body, an electrically controlled valve is fixedly connected to the rear side of the vent pipe, a pull rod is movably sleeved on the inner side of the vent pipe, the front side of the pull rod is fixedly connected to the protruding plates on the left and right sides of the drawer box, and a piston is fixedly connected to the rear side of the pull rod.

[0012] Compared with the prior art, the present invention has the following beneficial effects: 1. This utility model provides a timed tracker for the culture cycle of peripheral blood and bone marrow cells. Based on the cooperation of the incubator body, control panel, alarm light, placement mechanism, placement drawer box, placement rack, isolation plate, fixing components, placement hole and placement slot, the timing module monitors each culture tube, so that the alarm light of the placement drawer box corresponding to the culture tube that has reached the set time will be triggered, thereby standardizing the placement operation of the placement rack, and greatly improving the yield of culture products in conjunction with the control panel and alarm light.

[0013] 2. This utility model provides a timed tracker for the culture cycle of peripheral blood and bone marrow cells. Based on the cooperation of a placement drawer box, a placement frame, a fixing component, a limiting rod, a sliding seat, a push rod, a clamping plate, a spring, a placement hole, a damping component, a venting tube, an electric control valve, a pull rod, and a piston, the culture tube is fixed in the placement hole by the fixing component, and the drawer box is pulled out more stably by the damping component, thereby avoiding the impact of violent shaking on the culture tube, so that the culture tube can be moved stably each time it is picked up and put in. Attached Figure Description

[0014] Figure 1 This is a three-dimensional structural diagram of the present invention; Figure 2 This is a three-dimensional structural diagram of the incubator body of this utility model; Figure 3 This is a partial cross-sectional three-dimensional structural diagram of the placement mechanism of this utility model; Figure 4 This utility model Figure 3Enlarged structural diagram of part A in the middle; Figure 5 This is a partial cross-sectional three-dimensional structural diagram of the mounting frame portion of this utility model; Figure 6 This is a three-dimensional structural diagram of the fixing component of this utility model.

[0015] In the diagram: 1. Incubator body; 2. Door; 3. Control panel; 4. Alarm light; 5. Placement mechanism; 51. Placement drawer box; 52. Placement rack; 53. Isolation plate; 54. Fixing assembly; 541. Limiting rod; 542. Slide; 543. Push rod; 544. Clamping plate; 545. Spring; 55. Placement hole; 56. Pick-up and drop-off slot; 57. Damping assembly; 571. Vent pipe; 572. Electric control valve; 573. Pull rod; 574. Piston; 58. Placement slot. Detailed Implementation

[0016] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0017] like Figures 1-6 As shown, a timed tracker for the culture cycle of peripheral blood and bone marrow cells includes a culture chamber body 1, a door 2 rotatably connected to the front of the culture chamber body 1, a control panel 3 movably installed on the outside of the culture chamber body 1, several vertically distributed alarm lights 4 fixedly connected to the left side of the culture chamber body 1, and several vertically distributed mounting mechanisms 5 movably sleeved on the inside of the culture chamber body 1. The placement mechanism 5 includes a placement drawer box 51, a placement frame 52 is movably sleeved on the inner side of the placement drawer box 51, a number of rectangular placement holes 55 are opened on the upper side of the placement frame 52, a number of ring-shaped fixing components 54 are movably sleeved on the inner side of each of the placement holes 55, and two damping components 57 are fixedly connected to the left and right sides of the placement drawer box 51.

[0018] It should be noted that the incubator body 1 is used to maintain the temperature, humidity and other culture requirements inside the placement drawer box 51. This is existing technology and will not be described in detail here. The control panel 3 contains components such as a display, input module, remote control module, and timer module. When the culture tube reaches the predetermined time, the timer module controls the alarm light 4 to generate an alarm. The remote control module allows the user to connect via a handheld device. The input module allows the user to input the inoculation date, harvest date, and experimental indicator light data for each placement rack 52 on each layer by operating the display. The system can automatically calculate the harvest date. The placement hole 55 has a variety of structural shapes. Based on the existing culture tube shapes, it can be round, square, or other shapes. At the same time, the inner side of the placement hole 55 is inclined at 5 degrees to adapt to the culture conditions.

[0019] like Figure 5 As shown, the lower side of the mounting frame 52 has several ring-shaped mounting slots 58.

[0020] It should be noted that sensors, such as gravity sensors, can be placed in the placement tank 58. Remote modules, batteries, and other components can be installed on the placement rack 52. When a culture tube that has not reached the predetermined time is removed, the gravity sensor detects this situation and generates an alarm by connecting to the control panel 3 via the remote module.

[0021] like Figure 5 As shown, the upper side of the mounting frame 52 has several rectangularly distributed pick-and-place slots 56.

[0022] It should be noted that the inlet / outlet 56 is for easy access to the culture tubes.

[0023] like Figure 3 As shown, an isolation plate 53 is movably fitted onto the inner side of the drawer box 51.

[0024] It should be noted that the isolation plate 53 is made of transparent material, and a label can be inserted from the top to enter the isolation plate 53. When the number of culture tubes is small, a smaller placement rack 52 can be used. At the same time, the isolation plate 53 isolates the placement racks 52 on the left and right sides. When the placement rack 52 is removed, the information of the culture tubes inside the removed placement rack 52 can be clearly displayed.

[0025] like Figure 5 , Figure 6 As shown, the fixing component 54 includes a limiting rod 541. The upper and lower ends of the limiting rod 541 are fixedly connected to the inner side of the mounting frame 52. Two upper and lower sliding blocks 542 are movably sleeved on the outer side of the limiting rod 541. Push rods 543 are rotatably connected to the side of the two sliding blocks 542 near the mounting hole 55. A clamping plate 544 is rotatably connected to the side of the push rod 543 away from the limiting rod 541. The outer side of the clamping plate 544, away from the limiting rod 541, is movably sleeved on the inner side of the mounting hole 55. Two upper and lower springs 545 are movably sleeved on the outer side of the limiting rod 541. The springs 545 are located on the side of the two sliding blocks 542 that are far away from each other.

[0026] It should be noted that the spring 545 pushes the slide 542, causing the clamping plate 544 to clamp the culture tube. All clamping plates 544 have rubber pads on the side that is close to each other to increase the friction between the clamping plate 544 and the culture tube and prevent the clamping from loosening.

[0027] like Figure 6 As shown, the clamping plate 544 is made of a highly wear-resistant material.

[0028] It should be noted that the clamp 544 can be made of highly wear-resistant plastic to avoid the problem of excessive wear caused by repeated insertion and removal of culture tubes.

[0029] like Figure 4 As shown, the damping assembly 57 includes a vent pipe 571. The outer side of the vent pipe 571 is fixedly connected to the left and right sides of the inner side of the incubator body 1. An electric control valve 572 is fixedly connected to the rear side of the vent pipe 571. A pull rod 573 is movably sleeved on the inner side of the vent pipe 571. The front side of the pull rod 573 is fixedly connected to the protruding plates on the left and right sides of the drawer box 51. A piston 574 is fixedly connected to the rear side of the pull rod 573.

[0030] It should be noted that the electronically controlled valve 572 can control the size of the opening on the rear side of the vent pipe 571 by electronic control, thereby providing damping when the drawer box 51 is pulled out and installed, and preventing the drawer box 51 from being pulled out and installed quickly.

[0031] The working principle of this utility model is as follows: First, the control panel 3 contains components such as a display, input module, remote control module, and timing module. When the culture tube reaches the predetermined time, the timing module controls the alarm light 4 to generate an alarm. The remote control module allows the user to connect via a handheld device. The input module allows the user to input the inoculation date, harvest date, and experimental indicator light data for each shelf 52 of each layer through the display. The system can automatically calculate the harvest date. Sensors, such as gravity sensors, can be placed in the shelf 58. Remote modules, batteries, and other components can be installed on the shelf 52. When a culture tube that has not reached the predetermined time is removed, the gravity sensor detects this situation and generates an alarm by connecting to the control panel 3 via the remote module. The timing module monitors each culture tube, ensuring that only culture tubes that have reached the set time are removed. The alarm light 4 corresponding to the placement drawer box 51 triggers an alarm, thereby standardizing the placement operation of the placement rack 52. In conjunction with the control panel 3 and the alarm light 4, the yield rate of culture is greatly improved. Finally, the spring 545 pushes the slide 542, causing the clamping plate 544 to clamp the culture tube. All clamping plates 544 have rubber pads on the side close to each other to increase the friction between the clamping plate 544 and the culture tube and prevent the clamping from loosening. The electric control valve 572 can control the size of the opening on the rear side of the vent pipe 571, thereby providing damping when the placement drawer box 51 is pulled out, preventing the placement drawer box 51 from being pulled out quickly. The culture tube is fixed in the placement hole 55 by the fixing component 54. The damping component 57 makes the pulling out of the placement drawer box 51 more stable, thereby avoiding the impact of violent shaking on the culture tube, so that the culture tube can be moved stably every time it is picked up and put down.

[0032] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A timer tracker for the culture cycle of peripheral blood and bone marrow cells, comprising an incubator body (1), characterized in that: The incubator body (1) is rotatably connected to the front door (2), the incubator body (1) is movably installed with a control panel (3), the incubator body (1) is fixedly connected with several vertically distributed alarm lights (4), and the incubator body (1) is movably fitted with several vertically distributed placement mechanisms (5). The placement mechanism (5) includes a placement drawer box (51), and a placement frame (52) is movably sleeved on the inner side of the placement drawer box (51). The upper side of the placement frame (52) is provided with a number of rectangular placement holes (55). A number of ring-shaped fixing components (54) are movably sleeved on the inner side of each of the placement holes (55). Two damping components (57) are fixedly connected to the left and right sides of the placement drawer box (51).

2. The timer tracker for peripheral blood and bone marrow cell culture cycles according to claim 1, characterized in that: The lower side of the mounting frame (52) has several ring-shaped mounting slots (58).

3. A timed tracker for peripheral blood and bone marrow cell culture cycles according to claim 1, characterized in that: The upper side of the mounting frame (52) is provided with several rectangular slots (56).

4. A timed tracker for peripheral blood and bone marrow cell culture cycles according to claim 1, characterized in that: The inner side of the drawer box (51) is movably fitted with an isolation plate (53).

5. A timed tracker for peripheral blood and bone marrow cell culture cycles according to claim 1, characterized in that: The fixing component (54) includes a limiting rod (541), the upper and lower ends of which are fixedly connected to the inner side of the mounting frame (52). Two slides (542) distributed vertically are movably sleeved on the outer side of the limiting rod (541). Push rods (543) are rotatably connected to the side of the two slides (542) near the mounting hole (55). A clamping plate (544) is rotatably connected to the side of the push rod (543) away from the limiting rod (541). The outer side of the clamping plate (544) away from the limiting rod (541) is movably sleeved on the inner side of the mounting hole (55). Two springs (545) distributed vertically are movably sleeved on the outer side of the limiting rod (541). The springs (545) are located on the side of the two slides (542) that are far away from each other.

6. A timed tracker for peripheral blood and bone marrow cell culture cycles according to claim 5, characterized in that: The clamp (544) is made of a highly wear-resistant material.

7. A timed tracker for peripheral blood and bone marrow cell culture cycles according to claim 1, characterized in that: The damping assembly (57) includes a vent pipe (571), the outer side of which is fixedly connected to the left and right sides of the inner side of the incubator body (1), an electric control valve (572) is fixedly connected to the rear side of the vent pipe (571), a pull rod (573) is movably sleeved on the inner side of the vent pipe (571), the front side of the pull rod (573) is fixedly connected to the convex plates on the left and right sides of the drawer box (51), and a piston (574) is fixedly connected to the rear side of the pull rod (573).

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