A tumor cell smear sealing mechanism

Abstract

The utility model relates to cell smear technical field, concretely is a kind of tumour cell smears's sealing piece mechanism, the utility model includes support pedestal, further includes: horizontal transfer mechanism, set up on support pedestal, for carrying and horizontal transfer glass slide;Adsorption positioning mechanism, set up on horizontal transfer mechanism, for adsorption fixed glass slide;Resin blanking mechanism, set up above horizontal transfer mechanism, including control container and the quantitative container for being located in its interior, quantitative container is used to accommodate fixed capacity resin, the utility model utilizes to quantitative container drop in excess resin, excess resin falls into the resin accommodating mechanism below, realizes quantitative container to accommodate fixed content resin to add, so that when tumour cell smears, it can drop fixed content resin, avoid the resin of drop too much to cause between cover glass and glass slide coating too thick, increase the scattering when light passes through glass, affect the definition of smear observation.

Description

Technical Field

[0001] This utility model relates to the field of cell smear technology, specifically a sealing mechanism for tumor cell smears. Background Technology

[0002] In routine work at a pathology laboratory, mounting tumor cell smears is a crucial step in ensuring the quality of microscopic observation and long-term preservation of specimens. Proper mounting involves placing an appropriate amount of resin on a glass slide and covering it with a coverslip to protect the cell morphology and structure.

[0003] Currently, laboratories generally use manual resin dispensing for slide sealing. Operators use droppers or pipettes to directly add resin to the glass slide and then cover it with a coverslip for sealing.

[0004] This method has the problem of difficulty in precisely controlling the amount of resin used: too much resin will result in an excessively thick adhesive layer, causing light scattering and affecting the clarity of observation, while also easily causing resin to overflow and contaminate the slide; too little resin will not be able to completely cover the cell area, and air bubbles are easily generated during sealing, resulting in poor sealing. Utility Model Content

[0005] The purpose of this invention is to provide a mounting mechanism for tumor cell smears to solve the problems mentioned in the background art.

[0006] The objective of this utility model can be achieved through the following technical solutions: A mounting mechanism for tumor cell smears includes a support base and further includes: A lateral transfer mechanism, mounted on a support base, is used to carry and laterally transfer glass slides; An adsorption positioning mechanism, mounted on the transverse conveying mechanism, is used to adsorb and fix the glass slide; The resin feeding mechanism is located above the transverse conveying mechanism and includes a control container and a metering container inside it. The metering container is used to hold a fixed amount of resin, and the bottom of the control container is provided with a feeding pipe. The metering container is connected to a control mechanism, which is used to control the release of the resin contained in the metering container.

[0007] The lateral transfer mechanism includes a chute formed on a support base, a guide rod fixed inside the chute, a sliding plate slidably connected to the guide rod, and a support plate fixed to the top of the sliding plate; The support plate is equipped with a magnetic adsorption seat for adsorbing and fixing the resin receiving mechanism with an iron bottom.

[0008] The adsorption positioning mechanism includes an adsorption bracket fixed to the top of the support plate. The adsorption bracket has a cavity inside and a negative pressure adsorption hole at the top. The support plate is also equipped with a vacuum pump that is connected to the adsorption bracket through a pipe.

[0009] Preferably, a support ring is fixedly connected to the outside of the control container, and a support rod is fixedly connected to one side of the support base. The top of the support rod is fixedly connected to the support ring to provide support for the control container. A side plate is fixedly connected to one side of the support ring, and a support block is fixedly connected to the top of the side plate. A control mechanism is installed on the support block.

[0010] Preferably, both the metering container and the regulating container are semi-circular. The metering container includes a first and a second assembly that can be opened and closed relative to each other. The control mechanism is used to drive the second assembly to move horizontally relative to the first assembly.

[0011] Preferably, the control mechanism includes an adjusting screw, which is threadedly connected to the support block, and one end of the adjusting screw is rotatably connected to the transverse shaft fixed to the second assembly; a T-shaped rod is fixed inside the adjusting container, and a transverse plate fixed to the transverse shaft is slidably connected to the T-shaped rod.

[0012] Preferably, the metering container is a complete semi-circular container, and the control mechanism includes an adjustment rod, one end of which is fixedly connected to the metering container and used to drive the metering container to rotate around its axis; The control rod is rotatably connected to the support block via a bearing. An auxiliary plate is fixedly connected inside the control container. The control rod and the auxiliary plate are rotatably connected at their center via a bearing.

[0013] Preferably, a tumor cell smear sealing mechanism further includes a locking mechanism, which includes a threaded sleeve fixed to a side plate and a fixed ball fixed to a control rod. The bottom of a locking shaft passes through the fixed ball and is threadedly connected to the threaded sleeve to lock the rotation of the control rod.

[0014] The beneficial effects of this utility model are: This invention utilizes the method of adding excess resin to a quantitative container, with the excess resin falling into the resin receiving mechanism below. This allows the quantitative container to hold a fixed amount of resin for addition, ensuring that a fixed amount of resin is added during tumor cell smear preparation. This avoids the problem of adding too much resin, which would result in an excessively thick coating between the coverslip and the slide, increasing light scattering as it passes through the slide and affecting the clarity of the smear observation. Conversely, insufficient resin could allow air to enter the unfilled spaces, forming numerous air bubbles and affecting the observation of the smear. Attached Figure Description

[0015] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Figure 1 This is a schematic diagram of the overall structure of Embodiment 1 of this utility model; Figure 2 yes Figure 1 Rear view of the central support base; Figure 3 yes Figure 1 Schematic diagram of the structure at the bottom of the central support base; Figure 4 yes Figure 1 Side view of the control container; Figure 5 This is a structural schematic diagram of Embodiment 2 of this utility model; Figure 6 This is a structural schematic diagram of Embodiment 3 of this utility model; Figure 7 yes Figure 6 Enlarged view of point A in the middle.

[0016] The attached figures are labeled as follows: 1. Support base; 201. Slide groove; 202. Guide rod; 203. Sliding plate; 204. Support plate; 205. Magnetic adsorption seat; 206. Handle; 301. Adsorption bracket; 302. Negative pressure adsorption hole; 303. Vacuum pump; 401. Control container; 402. Feed pipe; 403. Support ring; 404. Support connecting rod; 5. Quantitative container; 501. First assembly part; 502. Second assembly part; 503. Arc-shaped connecting shaft; 601. Control screw; 602. Operating lever; 603. Horizontal shaft; 604. Horizontal plate; 605. T-shaped rod; 701. Control lever; 702. Auxiliary plate; 801. Threaded sleeve; 802. Fixed ball; 803. Locking shaft; 9. Side plate; 901. Support block. Detailed Implementation

[0017] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0018] Example 1 like Figures 1-4 A mounting mechanism for tumor cell smears includes a support base 1, a lateral conveying mechanism, an adsorption positioning mechanism, and a resin feeding mechanism. The transverse transfer mechanism is used for transverse transfer of glass slides. It includes a slide groove 201 opened on the support base 1. Two sets of parallel guide rods 202 are fixedly connected in the slide groove 201. A sliding plate 203 is slidably connected on the guide rods 202. A support plate 204 is fixedly connected to the top of the sliding plate 203. A magnetic adsorption seat 205 is fixedly connected to the support plate 204 by an embedded method. A resin holding mechanism can be adsorbed on the magnetic adsorption seat 205. The resin holding mechanism is a container in the prior art with an iron bottom. It can be adsorbed and positioned on the magnetic adsorption seat 205 and move together with the support plate 204. A handle 206 is fixedly connected to the top of one end of the support plate 204. By pulling the handle 206, the support plate 204 can be moved horizontally. When the support plate 204 moves, it causes the sliding plate 203 to move horizontally along the direction of the guide rod 202.

[0019] The adsorption positioning mechanism is used for the adsorption and positioning of a glass slide. The adsorption positioning mechanism includes an adsorption support 301, which is fixed to the top of a support plate 204. The interior of the adsorption support 301 is a cavity, and at least one negative pressure adsorption hole 302 is opened on the top of the support plate 204 and located on one side of the adsorption support 301. The vacuum pump 303 is existing technology, with a built-in power supply and a corresponding control switch. The vacuum pump 303 is connected to the adsorption support 301 through a pipe and can inflate or deflate the interior of the adsorption support 301. When deflated, it can reverse the air inside the adsorption support 301, so that the adsorption support 301 can perform negative pressure adsorption on the glass slide containing tumor cells through the negative pressure adsorption hole 302, so that the adsorption positioning mechanism can drive the glass slide to move stably together.

[0020] The resin feeding mechanism is located above the support plate 204. The resin feeding mechanism includes a semi-circular control container 401. The bottom of the control container 401 is fixedly connected to a feeding pipe 402. The feeding pipe 402 is located above the support plate 204 and can input the resin in the control container 401 into the glass slide adsorbed by the resin receiving mechanism or the adsorption positioning mechanism below through the feeding pipe 402. The control container 401 is externally fixedly connected to a support ring 403, and a support rod 404 is fixedly connected to one side of the support base 1. The top of the support rod 404 is fixedly connected to the support ring 403, providing support for the support ring 403 and the control container 401.

[0021] The regulating container 401 is equipped with a metering container 5. The top of the metering container 5 is an arc-shaped groove, which can hold a fixed amount of resin each time, and allows excess resin to overflow to the outside of the metering container 5 and enter the regulating container 401. The metering container 5, the regulating container 401, and the discharge pipe 402 are all made of PTEE (Teflon) material. The resin can flow in the metering container 5, the regulating container 401, and the discharge pipe 402 without adhering to the metering container 5, the regulating container 401, or the discharge pipe 402.

[0022] The quantitative container 5 includes a first assembly part 501 and a second assembly part 502 arranged symmetrically. The first assembly part 501 and the second assembly part 502 are assembled together to form a complete semi-circular quantitative container 5. The first assembly part 501 is fixed to the inner wall of the regulating container 401 by an arc-shaped connecting shaft 503. A side plate 9 is fixedly connected to one side of the support ring 403, and a support block 901 is fixedly connected to the top of the side plate 9. A control mechanism is provided on the support block 901. The control mechanism includes an adjusting screw 601. One end of the adjusting screw 601 is fixedly connected to an operating rod 602 with anti-slip texture, and the other end extends into the interior of the regulating container 401. A screw hole is provided on the support block 901 and is threadedly connected to the adjusting screw 601. A transverse shaft 603 is fixedly connected to one side of the second assembly 502. A transverse plate 604 is fixedly connected to the transverse shaft 603. Two T-shaped rods 605 are fixedly connected inside the control container 401. The transverse plate 604 and the T-shaped rods 605 are slidably connected to ensure the horizontal movement of the transverse plate 604, the transverse shaft 603 and the second assembly 502. One end of the control screw 601 located inside the control container 401 is rotatably connected to one end of the transverse shaft 603.

[0023] The working principle of the mounting mechanism for tumor cell smears provided in Embodiment 1 of this utility model is as follows: First, the movable support plate 204 moves the resin receiving mechanism above to the bottom of the feed pipe 402; Then, a certain amount of resin is drawn up using a dropper or pipette, and excess resin is transferred and dripped into the metering container 5. Excess resin can overflow to the outside of the metering container 5, enter the inside of the control container 401, and flow into the resin receiving mechanism below through the discharge pipe 402 at the bottom of the control container 401. Then, the support plate 204 is moved horizontally, and the slide with tumor cells adsorbed above the adsorption support 301 moves with the support plate 204 to the bottom of the feed tube 402. At this time, the control screw 601 can be rotated to drive the horizontal axis 603 and the second splicing part 502 to move horizontally. When the second splicing part 502 and the first splicing part 501 move away from each other, the resin inside the quantitative container 5 can drip onto the slide with tumor cells below. Finally, the horizontally movable support plate 204 allows the slide containing tumor cells to move to the outside of the feed tube 402. Then, a coverslip is manually picked up with tweezers and placed on the slide containing tumor cells to complete the mounting of the tumor cell smear.

[0024] Example 2 like Figure 5 Compared to Embodiment 1, in Embodiment 2 proposed in this application, the metering container 5 is a complete semi-circular container, and the control mechanism includes an adjustment rod 701. The adjustment rod 701 is rotatably connected to the support block 901 through a bearing. One end of the adjustment rod 701 extends into the control container 401 and is fixedly connected to the metering container 5, which can drive the metering container 5 to rotate so as to release the resin in the metering container 5. An auxiliary plate 702 is fixedly connected inside the control container 401. The center of the control rod 701 and the auxiliary plate 702 are rotatably connected by a bearing, so that the auxiliary plate 702 can provide auxiliary support for the control rod 701 and the metering container 5, ensuring the balance of the control rod 701 and the metering container 5.

[0025] The working principle of the mounting mechanism for tumor cell smears provided in Embodiment 2 of this utility model is as follows: First, move the support plate 204 to move the resin receiving mechanism above to below the feed pipe 402, and hold the rotating control rod 701 with one hand so that the opening of the metering container 5 faces upward. With the other hand, a certain amount of resin is drawn up using a dropper or pipette, and excess resin is transferred and dripped into the metering container 5. Excess resin can overflow to the outside of the metering container 5, enter the control container 401, and flow into the resin receiving mechanism below through the discharge pipe 402 at the bottom of the control container 401. Then, the support plate 204 is moved horizontally, and the slide with tumor cells adsorbed above the adsorption support 301 moves with the support plate 204 to below the feed tube 402. At this time, the control rod 701 can be manually rotated, and the control rod 701 drives the quantitative container 5 to rotate, so that the opening of the quantitative container 5 faces downward. At this time, the resin inside the quantitative container 5 drips into the control container 401, and then drips through the feed tube 402 onto the slide with tumor cells below. Finally, the horizontally movable support plate 204 allows the slide containing tumor cells to move to the outside of the feed tube 402. Then, a coverslip is manually picked up with tweezers and placed on the slide containing tumor cells to complete the mounting of the tumor cell smear.

[0026] By rotating the metering container 5, the resin in the metering container 5 is released, thus preventing leakage between the first assembly part 501 and the second assembly part 502 due to insufficient contact when the metering container 5 is divided into two parts.

[0027] Example 3 like Figure 6 and Figure 7 Compared to Embodiment 2, Embodiment 3 of this application further includes a locking mechanism. The locking mechanism includes a threaded sleeve 801 and a fixed ball 802. The threaded sleeve 801 is fixed to the top of the side plate 9, and the fixed ball 802 is fixed to the control rod 701. The fixed ball 802 has a through hole and a locking shaft 803. The bottom of the locking shaft 803 is threaded, and the bottom of the locking shaft 803 passes through the through hole on the fixed ball 802 and is threadedly connected to the threaded sleeve 801, thereby locking the fixed ball 802 and the control rod 701. This prevents the control rod 701 and the metering container 5 from rotating, and ensures that the top remains horizontal and does not tilt when locked.

[0028] This utility model provides a mounting mechanism for tumor cell smears. The operation method for mounting tumor cell smears is as follows: S1. Move the support plate 204 and move the external resin receiving mechanism adsorbed on the support plate 204 to the bottom of the feed pipe 402. Add excess resin to the metering container 5, so that the excess resin overflows into the control container 401 and finally flows into the resin receiving mechanism below the feed pipe 402. S2. The glass slide is then adsorbed by the adsorption positioning mechanism, and the support plate 204 drives the adsorption positioning mechanism and the glass slide to move to the bottom of the feed tube 402. S3. Apply tumor cells to the target area of ​​the glass slide that has been fixed and stained. S4. The fixed amount of resin in the quantitative container 5 is continuously released through the control mechanism, and the fixed amount of resin is dripped through the feed pipe 402 onto the glass slide coated with tumor cells below. S5. The movable support plate 204 drives the adsorption positioning mechanism and the glass slide after coating and resin dripping to move to the outside of the feed tube 402. S6. Using curved forceps, steadily grasp one edge of the coverslip. Place the side of the coverslip with the forceps into the slide, ensuring this edge is close to the front edge of the resin droplet. At this point, the coverslip and slide should form an angle of approximately 30-45 degrees. Slowly and steadily lower the forceps, allowing the coverslip to naturally "lie down." This action allows the resin to spread evenly forward like a wave from the point of contact, gradually expelling air and completing the mounting of the tumor cell smear.

[0029] The beneficial effects of the mounting mechanism for tumor cell smears provided by this utility model are as follows: This invention utilizes the addition of excess resin to a quantitative container 5, with the excess resin falling into the resin-containing mechanism below. This allows the quantitative container 5 to hold a fixed amount of resin for addition, ensuring that a fixed amount of resin is added during tumor cell smear preparation. This avoids the problem of adding too much resin, which would result in an excessively thick coating between the coverslip and the slide, increasing light scattering as it passes through the slide and affecting the clarity of the smear observation. Conversely, insufficient resin could allow air to enter the unfilled spaces, forming numerous air bubbles and affecting the observation of the smear.

[0030] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model.

Claims

1. A mounting mechanism for tumor cell smears, comprising a support base (1), characterized in that, Also includes: A transverse transfer mechanism is provided on the support base (1) for carrying and transversely transferring glass slides; An adsorption positioning mechanism, mounted on the transverse conveying mechanism, is used to adsorb and fix the glass slide; The resin feeding mechanism is located above the transverse conveying mechanism and includes a control container (401) and a metering container (5) located inside it. The metering container (5) is used to hold a fixed amount of resin. The bottom of the control container (401) is provided with a feeding pipe (402). The metering container (5) is connected to a control mechanism, which is used to control the metering container (5) to release the resin contained therein.

2. The mounting mechanism for a tumor cell smear according to claim 1, characterized in that, The transverse transfer mechanism includes a slide groove (201) opened on the support base (1), a guide rod (202) fixed in the slide groove (201), a sliding plate (203) slidably connected on the guide rod (202), and a support plate (204) fixed on the top of the sliding plate (203). The support plate (204) is provided with a magnetic adsorption seat (205) for adsorbing and fixing the resin receiving mechanism with an iron bottom.

3. The mounting mechanism for a tumor cell smear according to claim 2, characterized in that, The adsorption positioning mechanism includes an adsorption bracket (301) fixed to the top of the support plate (204). The adsorption bracket (301) has a cavity inside and a negative pressure adsorption hole (302) is opened at the top. The support plate (204) is also equipped with a vacuum pump (303) that is connected to the adsorption bracket (301) through a pipe.

4. The mounting mechanism for a tumor cell smear according to claim 1, characterized in that, The control container (401) is fixedly connected to a support ring (403), and a support rod (404) is fixedly connected to one side of the support base (1). The top of the support rod (404) is fixedly connected to the support ring (403) to provide support for the control container (401). A side plate (9) is fixedly connected to one side of the support ring (403), and a support block (901) is fixedly connected to the top of the side plate (9). A control mechanism is provided on the support block (901).

5. The mounting mechanism for a tumor cell smear according to claim 4, characterized in that, Both the quantitative container (5) and the regulating container (401) are semi-circular. The quantitative container (5) includes a first assembly part (501) and a second assembly part (502) that can be opened and closed relative to each other. The control mechanism is used to drive the second assembly part (502) to move horizontally relative to the first assembly part (501) by opening and closing.

6. The mounting mechanism for a tumor cell smear according to claim 5, characterized in that, The control mechanism includes an adjusting screw (601), which is threadedly connected to a support block (901), and one end of which is rotatably connected to a transverse shaft (603) fixed to the second assembly (502); a T-shaped rod (605) is fixed inside the adjusting container (401), and a transverse plate (604) fixed to the transverse shaft (603) is slidably connected to the T-shaped rod (605).

7. The mounting mechanism for a tumor cell smear according to claim 4, characterized in that, The quantitative container (5) is a complete semi-circular container. The control mechanism includes an adjustment rod (701). One end of the adjustment rod (701) is fixedly connected to the quantitative container (5) and is used to drive the quantitative container (5) to rotate around its axis. The control rod (701) is rotatably connected to the support block (901) via a bearing. An auxiliary plate (702) is fixedly connected inside the control container (401). The center of the control rod (701) and the auxiliary plate (702) are rotatably connected via a bearing.

8. The mounting mechanism for a tumor cell smear according to claim 7, characterized in that, It also includes a locking mechanism, which includes a threaded sleeve (801) fixed on the side plate (9) and a fixed ball (802) fixed on the control rod (701). The bottom of the locking shaft (803) passes through the fixed ball (802) and is threadedly connected to the threaded sleeve (801) to lock the rotation of the control rod (701).

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