A peptide protein drying apparatus

Abstract

The utility model provides a kind of peptide protein drying equipment, including drying tank body, the upper fixed mounting of drying tank body is equipped with high-speed centrifugal atomizer, the upper installation of high-speed centrifugal atomizer is equipped with injection pipe orifice, and its lower end is equipped with high-speed spray head;Drying tank body upper installation is equipped with high-efficiency air supply device, and the lower of drying tank body is provided with discharge pipe orifice;High temperature outer cover fixedly installed outside drying tank body is respectively provided with exhaust pipe orifice and injection pipe orifice, and the inside of drying tank body is equipped with guide vane;The utility model high-efficiency air supply device double air path cooperation: inner air supply port precision drying atomized droplet, outer air supply port forms spiral hot air full domain coverage, improves heat utilization and peptide protein activity;Triple anti-sticking design reduces loss, airflow and guide vane guarantee drying uniformity.

Description

Technical Field

[0001] This utility model belongs to the field of peptide protein drying technology, and in particular relates to a peptide protein drying device. Background Technology

[0002] Peptides, as functional macromolecules with specific biological activities, are widely used in pharmaceuticals, food and health products, and animal feed. Their molecular structure is sensitive to temperature, humidity, and mechanical forces, and they are prone to thermal denaturation, loss of activity, and aggregation during drying, severely impacting product quality and production efficiency. Currently, commonly used peptide drying equipment in the industry mainly suffers from the following technical challenges: While freeze dryers can preserve peptide activity to the greatest extent, they suffer from high energy consumption, long processing cycles (several hours per batch), and large equipment investment, making it difficult to meet the needs of industrial mass production. Ordinary spray dryers achieve rapid drying by contacting atomized droplets with hot air, but the hot air is mostly in a single co-current or counter-current mode, and uneven airflow dispersion leads to some droplets being overheated (causing denaturation) and some droplets not drying sufficiently (forming agglomeration), resulting in generally low activity retention rates.

[0003] Peptide protein molecules contain polar groups, and after atomization, they are easily adhered to the inner wall of the drying tank due to factors such as electrostatic adsorption and localized cooling and solidification. Traditional equipment relies on manual cleaning or simple hot air blowing, and the wall adhesion loss rate is usually 5%-10%. This not only wastes raw materials, but also makes the residual materials prone to deterioration, increasing the risk of cross-contamination between batches, and making it difficult to meet the GMP (Good Manufacturing Practice) requirements in the food and pharmaceutical fields.

[0004] Therefore, it is essential to invent a peptide drying device. Utility Model Content

[0005] To solve the above-mentioned technical problems, this utility model provides a peptide protein drying device, including a drying tank, a high-speed centrifugal atomizer, a feeding port, a high-speed nozzle, a high-efficiency blower, a discharge port, a high-temperature outer cover, an exhaust port, an injection port, and guide vanes. The high-speed centrifugal atomizer is fixedly installed on the top of the drying tank, and the feeding port is installed above the high-speed centrifugal atomizer, with the high-speed nozzle installed at its lower end. The high-efficiency blower is installed on the top of the drying tank, and the discharge port is located at the bottom of the drying tank. The high-temperature outer cover fixedly installed on the outside of the drying tank is provided with an exhaust port and an injection port, respectively. The guide vanes are installed inside the drying tank.

[0006] Preferably, the high-efficiency air supply device includes an air supply base, an inner air supply ring, an air inlet, a main channel, an inner air outlet, a spiral air supply channel, and an outer air outlet. The air supply base is fixedly installed inside the upper part of the drying tank and located outside the high-speed nozzle. The inner air supply ring is provided on the upper inner side of the air supply base. The air inlet integrally provided on the air supply base is connected to the main channel provided inside it. The air inlet is fixedly installed on the drying tank and extends outward. The main channel, spiral air supply channel, and outer air outlet of the air supply base are interconnected with the inner air outlet of the inner air supply ring.

[0007] Preferably, the inner air supply ring disposed above the air supply seat is located above the high-speed nozzle, and the inner air supply ports arranged in a circular array inside the inner air supply ring are located in an inverted "L"-shaped channel structure, with its horizontal part connected to the main channel and its vertical part located above the high-speed nozzle.

[0008] Preferably, the main channel inside the air supply seat is connected to the hot air heater through the air inlet. The air supply seat has four spiral air supply channels with the same direction of rotation. Each spiral air supply channel is connected to an external air outlet outside the corresponding air supply seat. The hot air discharged from the external air outlet can act on the inner wall of the drying tank at an inclined angle and form a spiral path of hot air.

[0009] Preferably, the spiral air supply channel inside the air supply seat has the same rotation direction as the guide blade, and the guide blade is a conical spiral blade, which is installed on the inner wall of the conical part below the drying tank.

[0010] Preferably, a high-temperature outer cover is fixedly installed on the outside of the conical part below the drying tank. The injection port of the high-temperature outer cover is connected to the high-temperature steam generator, and the exhaust port is connected to the steam recovery unit.

[0011] Compared with the prior art, the present invention has the following beneficial effects: This utility model's high-efficiency air supply device features a dual-airflow design with an internal air outlet and an external air outlet, creating a synergistic effect: the inverted "L"-shaped internal air outlet of the internal airflow ring precisely guides hot air to the atomization core area below the nozzle, allowing droplets to instantly contact the hot air and rapidly dehydrate (drying time reduced to 1-3 seconds); four spiral airflow channels rotating in the same direction form a spiral hot airflow along the tank wall through the external air outlet, achieving full coverage. This dual-airflow synergy improves hot air utilization, and the short drying cycle significantly enhances peptide and protein activity retention, solving the industry challenge of "efficiency and activity being mutually exclusive."

[0012] This invention utilizes an inclined hot air outlet to form a spiral air film along the tank wall, preventing atomized droplets from directly impacting the inner wall at the source. The guide blades of the conical spiral structure align with the spiral hot air's rotation direction, enhancing airflow stability and guiding the flow through the blade surface to scrape away any adhering material from the inner wall and re-entrain it into the drying zone. The high-temperature outer casing of the conical section at the bottom of the drying tank maintains a stable wall temperature through steam heating, preventing material from solidifying and sticking to the wall due to localized cooling. This triple anti-sticking design reduces material loss to below 2%, minimizes inner wall residue, reduces manual cleaning frequency, meets GMP cleaning requirements, and significantly reduces the risk of cross-contamination.

[0013] The concentrated hot air from the internal air outlet and the spiral hot air from the external air outlet of this invention form a stable airflow field of "central convergence + edge spiral" inside the tank, ensuring that all droplets have a uniform drying path and are heated evenly; the conical guide blades guide the material to move down in an orderly manner along the spiral trajectory, avoiding "over-drying" or "under-drying" caused by airflow turbulence. Attached Figure Description

[0014] Figure 1 This is a partial cross-sectional structural diagram of the present invention.

[0015] Figure 2 This is a schematic diagram of the overall structure of this utility model.

[0016] Figure 3 This is a half-sectional structural diagram of the high-efficiency air supply device of this utility model.

[0017] In the picture: 1. Drying tank; 2. High-speed centrifugal atomizer; 3. Injection port; 4. High-speed nozzle; 5. High-efficiency blower; 6. Air supply seat; 7. Inner air supply ring; 8. Air inlet; 9. Main channel; 10. Inner air outlet; 11. Spiral air supply channel; 12. Outer air outlet; 13. Discharge port; 14. High-temperature outer cover; 15. Exhaust port; 16. Injection port; 17. Guide vanes. Detailed Implementation

[0018] To enable those skilled in the art to better understand the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort should fall within the protection scope of the present invention.

[0019] In the description of the embodiments, it should be noted that the terms "upper," "lower," "inner," "outer," "front end," "rear end," "both ends," "one end," and "the other end," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the present invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. In the description of the utility model, it should be noted that unless otherwise explicitly specified and limited, the terms "installed," "equipped with," "connected," etc., should be interpreted broadly. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components. Those skilled in the art can understand the specific meaning of the above terms in the present utility model based on the specific circumstances.

[0020] As attached Figure 1 To be continued Figure 3 As shown: This utility model provides a peptide protein drying device, comprising a drying tank 1, a high-speed centrifugal atomizer 2, a feeding port 3, a high-speed nozzle 4, a high-efficiency blower 5, a discharge port 6, a high-temperature outer cover 7, an exhaust port 8, an injection port 9, and guide vanes 10. The high-speed centrifugal atomizer 2 is fixedly installed on the top of the drying tank 1, the feeding port 3 is installed above the high-speed centrifugal atomizer 2, and the high-speed nozzle 4 is installed at its lower end. The high-efficiency blower 5 is installed on the top of the drying tank 1, and the discharge port 6 is located at the bottom of the drying tank 1. The high-temperature outer cover 7, which is fixedly installed on the outside of the drying tank 1, is provided with an exhaust port 8 and an injection port 9. The guide vanes 10 are installed inside the drying tank 1.

[0021] Furthermore, the high-efficiency air supply unit 5 includes an air supply base 51, an inner air supply ring 52, an air inlet 53, a main channel 54, an inner air outlet 55, a spiral air supply channel 56, and an outer air outlet 57. The air supply base 51 is made of 316L stainless steel and is bolted to a flange located inside the drying tank 1. The air supply base 51 has an overall annular structure, fitted over the high-speed nozzle 4, with a 5-8mm safety gap between its inner wall and the outer wall of the high-speed nozzle 4 to prevent collisions during operation. An inner air supply ring 52, also made of 316L stainless steel, is fixedly installed on the upper inner side of the air supply base 51 by welding. An air inlet 53, integrally formed with the air supply base 51, penetrates the side wall of the air supply base 51. One end of the air inlet 53 connects to the main channel 54 inside the air supply base 51, while the other end is fixedly installed at an opening in the side wall of the drying tank 1 via a flange, extending out of the drying tank 1 for easy connection to an external hot air supply pipeline. Furthermore, the main channel 54 inside the air supply base 51 is interconnected with the spiral air supply channel 56, the external air outlet 57, and the internal air outlet 55 on the inner air supply ring 52, forming a complete hot air delivery path.

[0022] Furthermore, an inner air supply ring 52 is positioned above the high-speed nozzle 4 within the air supply base 51, with their axes coinciding and a spacing of 10-15 mm. The inner air supply ring 52 contains 8-12 internal air supply ports 55 arranged in a circular array along its circumference. Each internal air supply port 55 is an inverted "L"-shaped channel structure. One horizontal end of the internal air supply port 55 connects to the main channel 54, with a rounded transition design at the connection point to reduce air resistance. The other horizontal end bends vertically downwards to form a vertical section, with the outlet of the vertical section facing directly above the spray area of ​​the high-speed nozzle 4, ensuring that the hot air accurately acts on the freshly atomized peptide droplets. The connection between the inner air supply ring 52 and the air supply base 51 is sealed using argon arc welding to prevent hot air leakage.

[0023] Furthermore, the main channel 54 inside the air supply base 51 is an annular cavity structure. The main channel 54 is connected to the air outlet of the external hot air heater via a sealed metal hose through the air inlet 53. Four spiral air supply channels 56 with the same rotation direction are evenly arranged around the main channel 54 inside the air supply base 51. The spiral air supply channels 56 are welded from 316L stainless steel plates, with a spiral angle of 30°-45° and a circular cross-section. One end of each spiral air supply channel 56 is connected to the main channel 54, and the other end extends to the outer wall of the air supply base 51 and communicates with the corresponding external air outlet 57. The external air outlet 57 is an inclined tubular structure, forming an angle of 45°-60° with the outer wall of the air supply base 51. Its outlet faces the inner wall of the drying tank 1, and the four external air outlets 57 are evenly distributed along the circumference of the air supply base 51, ensuring that the discharged hot air can act on the inner wall of the drying tank 1 at an inclined angle, forming a continuous spiral path of hot air within the tank. The end of the external air outlet 57 is polished to prevent turbulence during hot air delivery.

[0024] Furthermore, the spiral air supply channel 56 inside the air supply base 51 has the same rotation direction as the guide vanes 10 (both clockwise or both counterclockwise) to ensure coordinated airflow and material movement. The guide vanes 10 are conical spiral blades made of 316L stainless steel, and their spiral angle matches the spiral angle of the spiral air supply channel 56 (30°-45°). The guide vanes 10 are fixedly installed on the inner wall of the conical part below the drying tank 1 by welding or bolting. The outer edge of the blades is tightly fitted to the inner wall of the drying tank 1, and the inner edge maintains a distance of 50-80mm from the central axis of the conical part of the drying tank 1, forming a material conveying channel. The surface of the guide vanes 10 is coated with a polytetrafluoroethylene anti-stick coating to reduce the adhesion of peptide protein materials.

[0025] Furthermore, a high-temperature outer cover 7 is bolted to the outside of the conical section below the drying tank 1. The high-temperature outer cover 7 has a double-layer stainless steel structure, with an inner layer of 316L stainless steel and an outer layer of 304 stainless steel. A 50-80mm thick rock wool insulation layer is filled between the two layers for heat insulation. An injection port 9 on the side wall of the high-temperature outer cover 7 is connected to the output pipeline of an external high-temperature steam generator via a flange connection. The inner diameter of the injection port 9 is 20-30mm, and a valve is installed on the pipeline to control the steam flow. An exhaust port 8 at the top of the high-temperature outer cover 7 is also connected to the input pipeline of a steam recovery unit via a flange connection. The inner diameter of the exhaust port 8 is 25-35mm, facilitating the transport of condensate and residual steam from the high-temperature outer cover 7 to the steam recovery unit for recycling. A 10-15mm gap is maintained between the high-temperature outer cover 7 and the conical section of the drying tank 1 to ensure that steam can evenly coat the outer wall of the conical section.

[0026] The working principle is as follows: First, the peptide protein raw material enters the high-speed centrifugal atomizer 2 through the injection port 3. The high-speed centrifugal atomizer 2 is then started, causing the high-speed nozzle 4 at its lower end to rotate at high speed, atomizing the raw material into fine droplets and spraying them downwards into the drying tank 1. Simultaneously, hot air generated by the external hot air blower enters the main channel 54 of the high-efficiency air blower 5 through the air inlet 53. The hot air in the main channel 54 is delivered in two paths: one path flows into the inner air supply ring 52 and is blown vertically downwards through the inner air outlet 55 on the inner air supply ring 52, precisely acting on the atomized droplets sprayed by the high-speed nozzle 4 for initial rapid drying; the other path flows into the spiral air supply channel 56, and after being guided by the spiral air supply channel 56, is blown out obliquely from the outer air outlet 57, acting on the inner wall of the drying tank 1 and forming a continuous spiral path of hot air, drying the material inside the tank over its entirety while reducing material adhesion to the tank wall.

[0027] During this process, the steam generated by the external high-temperature steam generator enters the gap between the high-temperature outer cover 7 and the conical part of the drying tank 1 through the injection port 9 on the high-temperature outer cover 7, and heats the conical part below the drying tank 1 evenly, so as to prevent the material inside the tank from solidifying and sticking to the wall due to local cooling; the condensate and residual steam in the high-temperature outer cover 7 are transported to the steam recovery unit for recycling through the exhaust port 8.

[0028] Subsequently, the pre-dried peptide protein material moves downward along the inner wall of the drying tank 1 under the drive of the spiral hot air. After entering the lower conical part, it continues to move downward along the spiral trajectory under the guidance of the guide blades 10 that are in the same direction as the spiral hot air. During this process, it continuously comes into contact with the hot air to complete the deep drying. The guide blades 10 can also further scrape off any small amount of material that may be attached to the tank wall.

[0029] Finally, the completely dried peptide protein product is discharged through the discharge port 6 below the drying tank 1; at the same time, the unused residual steam and condensate in the high-temperature outer cover 7 continuously enter the steam recovery unit through the exhaust port 8 to realize the recycling of steam.

[0030] Any technical solution that achieves the above-mentioned technical effects by utilizing the technical solution described in this utility model, or by designing a similar technical solution inspired by the technical solution described in this utility model, falls within the protection scope of this utility model.

Claims

1. A peptide drying device, characterized in that, The equipment includes a drying tank (1), a high-speed centrifugal atomizer (2), a feeding port (3), a high-speed nozzle (4), a high-efficiency blower (5), a discharge port (6), a high-temperature outer cover (7), an exhaust port (8), an injection port (9), and guide vanes (10). The high-speed centrifugal atomizer (2) is fixedly installed on the top of the drying tank (1). The feeding port (3) is installed on the top of the high-speed centrifugal atomizer (2), and the high-speed nozzle (4) is installed at its lower end. The high-efficiency blower (5) is installed on the top of the drying tank (1), and the discharge port (6) is installed at the bottom of the drying tank (1). The high-temperature outer cover (7) fixedly installed on the outside of the drying tank (1) is provided with an exhaust port (8) and an injection port (9). The guide vanes (10) are installed inside the drying tank (1).

2. The peptide drying equipment as described in claim 1, characterized in that: The high-efficiency air supply device (5) includes an air supply seat (51), an inner air supply ring (52), an air inlet (53), a main channel (54), an inner air outlet (55), a spiral air supply channel (56), and an outer air outlet (57). The air supply seat (51) is fixedly installed inside the upper part of the drying tank (1) and located outside the high-speed nozzle (4). The inner air supply ring (52) is provided on the upper part of the inner side of the air supply seat (51). The air inlet (53) integrally provided on the air supply seat (51) is connected to the main channel (54) provided inside it. The air inlet (53) is fixedly installed on the drying tank (1) and extends outward. The main channel (54), spiral air supply channel (56), and outer air outlet (57) provided on the air supply seat (51) are interconnected with the inner air outlet (55) provided on the inner air supply ring (52).

3. The peptide drying equipment as described in claim 2, characterized in that: The inner air supply ring (52) located above the air supply seat (51) is positioned above the high-speed nozzle (4). The inner air supply ports (55) arranged in a circular array inside the inner air supply ring (52) are located in an inverted "L"-shaped channel structure. The horizontal part of the port is connected to the main channel (54), and the vertical part is located above the high-speed nozzle (4).

4. The peptide drying equipment as described in claim 3, characterized in that: The main channel (54) inside the air supply seat (51) is connected to the hot air generator through the air inlet (53). The air supply seat (51) is provided with four spiral air supply channels (56) in the same direction. Each spiral air supply channel (56) is connected to the external air outlet (57) provided outside the corresponding air supply seat (51). The hot air discharged from the external air outlet (57) can act on the inner wall of the drying tank (1) in an inclined manner and form a spiral path of hot air.

5. The peptide drying equipment as described in claim 4, characterized in that: The spiral air supply channel (56) inside the air supply seat (51) has the same rotation direction as the guide blade (10). The guide blade (10) is a conical spiral blade, which is installed on the inner wall of the conical part below the drying tank (1).

6. The peptide drying equipment as described in claim 5, characterized in that: A high-temperature outer cover (7) is fixedly installed on the outside of the cone-shaped part below the drying tank (1). The injection port (9) of the high-temperature outer cover (7) is connected to the high-temperature steam generator, and the exhaust port (8) is connected to the steam recovery unit.

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