A ready-to-use skin test solution preparation jar

Abstract

The application discloses a ready-to-use skin test liquid preparation tank, which comprises a sealed tank body, an upper chamber for containing medicine and a lower chamber for containing solvent in the tank body, a medicine outlet arranged on the tank body and connected with the lower chamber, and an activation assembly arranged on the tank body and connected with the upper chamber, wherein the activation assembly comprises an activation rod which is movable relative to the tank body, and a sharp end of the activation rod is arranged for puncturing the partition film. Compared with the prior art, the medicine and the solvent can be mixed by simple operation without any additional steps such as pumping and injection, and the mixed liquid can be pumped by a syringe after shaking, so that the operation time is greatly saved, and the work burden is reduced.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a ready-to-use sealed container for preparing skin test solutions. Background Technology

[0002] In clinical medicine, skin allergy tests are required before the use of drugs such as penicillin and cephalosporins. Currently, the skin test solution is prepared by nurses on the spot before medication, a cumbersome process: first, the solvent must be drawn, injected into the powder injection vial, shaken to dissolve and mix, and then a certain amount of the drug solution must be drawn for dilution before the required concentration of the skin test solution can be prepared. This process has the following drawbacks: 1. The operation is cumbersome, time-consuming and labor-intensive, increasing the workload of nurses and resulting in low efficiency in busy clinical work; 2. The preparation environment for skin test solutions is easily contaminated. The repeated aspiration and injection of the skin test solution into the syringe increases the risk of the solution being contaminated by microorganisms or particles. 3. Concentration accuracy is difficult to guarantee. The preparation of skin test solution depends on the nurse's personal operation skills. There is a risk of deviation in the concentration of skin test solution due to inaccurate aspiration volume, insufficient mixing, etc., which may affect the interpretation of skin test results, causing false positives or false negatives, and posing medical safety hazards. 4. Drug stability issues: Some drugs have a very short shelf life after dissolution. If temporary preparations are not properly managed, expired drug solutions may be used by mistake.

[0003] Chinese patent CN204995926U discloses a disposable skin test syringe, comprising a syringe barrel with an internal isolation membrane dividing the syringe barrel into a first isolation zone and a second isolation zone. The first isolation zone is located near the needle tip; the second isolation zone is located near the plunger. Powder is placed in the first isolation zone, and solvent is placed in the second isolation zone. It also includes a puncture device located inside the syringe barrel, comprising a needle head and a needle handle. The needle head is located outside the isolation membrane; the needle handle passes through the plunger, with its end extending above the plunger; the distance between the needle head and the isolation membrane is less than the distance between the needle handle and the plunger.

[0004] The aforementioned disposable skin test syringe combines a skin test solution container with a syringe. Because the needle is always positioned towards the isolation membrane, it is prone to accidental contact with the plunger under external force during transportation or handling, posing a risk of puncturing the isolation membrane. This could affect the mixing effect of the skin test solution and subsequent testing results. In addition, the solvent and powder in this disposable skin test syringe are pre-filled, which requires the pre-equipment of disposable skin test syringes containing various solvents and powders, increasing the hospital's usage costs. Utility Model Content

[0005] The present invention aims to overcome the defects in the prior art and provide a ready-to-use skin test solution preparation container that is simple in structure, easy to operate, has good sealing performance, and is safe and reliable.

[0006] To achieve the above-mentioned utility model objectives, the present utility model adopts the following technical solution: a ready-to-use skin test solution preparation container, comprising a sealed container body, the interior of which is divided into an upper chamber for containing drugs and a lower chamber for containing solvent by a partition membrane; a drug solution outlet disposed on the container body and connected to the lower chamber; and an activation component disposed on the container body and connected to the upper chamber, the activation component comprising an activation rod movable relative to the container body, the end of the activation rod being provided with a sharp portion for piercing the partition membrane.

[0007] As a further optimization of this utility model, the activation component further includes a connecting seat fixedly connected to the tank body, the connecting seat having a channel for the activation rod to pass through, and a sealing structure being provided between the activation rod and the connecting seat.

[0008] A further optimization of this utility model is that a positioning structure is provided between the activation rod and the connecting seat to prevent the activation rod from moving accidentally.

[0009] A further optimization of this invention is that the liquid extraction port is made of an elastic sealing material that can be pierced by a syringe needle.

[0010] A further optimization of this utility model is that the liquid extraction port and the activation component are respectively disposed at opposite ends of the tank.

[0011] A further optimization of this invention is that the canister is made of a transparent or translucent medical-grade polymer material.

[0012] Compared with the prior art, the beneficial effects of this utility model are as follows: 1. Easy to operate, ready to use immediately after mixing, improving efficiency; 2. Pre-packaged drugs and solvents ensure accurate concentrations; 3. Enclosed design reduces the risk of contamination; 4. Drug and solvent are separated to ensure stability; The drugs and solvents are pre-packaged precisely in a predetermined ratio at the time of manufacture, avoiding concentration errors that may be caused by human configuration and ensuring the accuracy and reliability of skin test results.

[0013] The entire device is completely sealed and will only be punctured by a sterile syringe needle when the liquid is drawn, which greatly reduces the risk of contamination of the drug solution during the preparation process.

[0014] The physical separation of the drug and solvent during storage ensures the long-term stability of the drug components and avoids the drug degradation problems that may occur with temporary preparation. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model; Figure 2 This is a sectional view of the tank. Figure 3 This is a schematic diagram of the activated component; Figure 4 This is a schematic diagram of the activation component structure with a ring-shaped sawtooth structure; Figure 5 This is a schematic diagram of the needle-shaped activation component structure; Figure 6 This is a structural diagram of the connector; Figure 7 This is a schematic diagram of the activation rod; Figure 8 This is a structural diagram of the tank; Reference numerals: Tank 1, Isolation membrane 11, Upper chamber 12, Lower chamber 13, Liquid extraction port 14, Guide strip 15, Activation component 2, Connecting seat 21, Activation rod 22, Sharp part 23, Annular cover 24, Groove 241, Push rod 25, Connecting channel 26, Sealing ring 27, Positioning block 28, Fitting block 29. Detailed Implementation

[0016] The embodiments of this utility model will now be described in detail with reference to the accompanying drawings.

[0017] like Figures 1-7 As shown, a ready-to-use skin test solution preparation container includes a container body 1 and a drug solution extraction port 14 formed on the surface of the container body 1; the container body 1 is provided with a partition membrane 11 for dividing the container body 1 into an upper chamber 12 and a lower chamber 13, and the upper chamber 12 and the lower chamber 13 are spaced apart under the action of the partition membrane 11; the end of the container body 1 is provided with an activation component 2 for breaking the partition membrane 11, the activation component 2 includes a connecting seat 21 and an activation rod 22 installed in the middle of the connecting seat 21, the middle of the connecting seat 21 is formed with a connecting channel 26 to facilitate pressing and rotating of the activation rod 22, the inner wall of the connecting channel 26 is formed with a positioning block 28 for positioning the initial position of the activation rod 22, and the end of the activation rod 22 is formed with a sharp part 23 facing the partition membrane 11.

[0018] The upper chamber 12 is pre-packaged with drug powder, and the lower chamber 13 is pre-packaged with a certain amount of solvent. The separation between the drug powder and the solvent is achieved by the action of the diaphragm 11. The activation component 2 is used to break the diaphragm 11 to achieve communication and mixing between the drug powder and the solvent.

[0019] The container 1 is integrally molded from transparent plastic (such as polypropylene PP or polycarbonate PC) that meets USP Class VI or the corresponding Chinese Pharmacopoeia standard through injection molding. The material should be selected to be of a type that has good compatibility with the drug being packaged, and should be verified through compatibility studies. It should also have low air permeability to prevent solvent evaporation.

[0020] The separator membrane 11 is a multi-layer composite membrane, including an inert material layer (such as polyester PET) and a heat-sealable layer (such as polyethylene PE or polypropylene PP). Its sealing strength ensures it will not break during transportation and storage, while also allowing it to be easily punctured by the activation rod. This membrane material undergoes rigorous leachate and adsorption studies to ensure drug stability. The edges of the separator membrane 11 are sealed to the inner wall of the tank 1 by hot-press welding or high-frequency welding, ensuring complete isolation between the upper chamber 12 and the lower chamber 13.

[0021] The liquid extraction port 14 and the activation component 2 are respectively installed at opposite ends of the tank body 1. The liquid extraction port 14 is located in the lower chamber 13, and the activation component 2 is located in the upper chamber 12. The liquid extraction port 14 is a septum made of pharmaceutical-grade bromobutyl rubber or silicone, and its self-sealing and puncture resistance meet relevant pharmaceutical standards. In use, the syringe needle is inserted into the septum to draw up the liquid.

[0022] The connecting seat 21 is installed at the top opening of the tank body 1 and is threadedly connected to the top of the tank body 1. A sealing ring 27, made of medical-grade silicone, is provided within the connecting channel 26 to abut against the activation rod 22. The thread and the sealing ring 27 together ensure a reliable seal between the connecting seat 21 and the top of the tank body 1.

[0023] The outer wall of the activation rod 22 is provided with a mating block 29 that abuts against the positioning block 28. In the initial state, the positioning block 28 abuts against the mating block 29 and forms a certain resistance to the activation rod 22 under the action of the sealing ring 27, so as to ensure the stability of the activation rod 22 in the initial position.

[0024] The pointed part 23 is a needle-shaped structure formed at the end of the activation rod 22. The needle-shaped structure is eccentrically set at the end of the activation rod 22. By pressing the activation component 2, the end of the activation rod 22 of the needle-shaped structure can puncture the diaphragm 11. As the activation rod 22 rotates, it drives the needle-shaped structure to move along a circular trajectory, accelerating the rupture of the diaphragm 11.

[0025] The sharp part 23 is an annular serrated structure formed at the end of the activation rod 22. By pressing the activation component 2, the end of the activation rod 22 with the annular serrated structure can puncture the partition membrane 11. As the activation rod 22 rotates, it drives the annular serrated structure to rotate, accelerating the rupture of the partition membrane 11.

[0026] The end of the activation rod 22 is provided with a push rod 25 for driving the activation rod 22 to press and rotate. The connecting seat 21 has an annular cover 24 for preventing the push rod 25 from being accidentally touched. The annular cover 24 has a slot 241 for facilitating the rotation of the push rod 25.

[0027] This product is supplied aseptically and undergoes ethylene oxide sterilization or irradiation sterilization before leaving the factory, achieving a sterility assurance level (SAL) of 10. -6 The inner wall of the tank 1 may be provided with guide strips 15 or protrusions to assist in the mixing of drugs and solvents.

[0028] In actual use, the isolation membrane 11 is pre-installed in the tank 1, and the upper chamber 12 is pre-sealed with drug powder and the lower chamber 13 is pre-sealed with a quantitative solvent. In the non-use state, the activation mechanism 2 is in the disposal state. At this time, the activation mechanism 2 maintains the integrity of the isolation membrane 11, so that the upper chamber 12 and the lower chamber 13 are completely isolated.

[0029] When the activation mechanism 2 rotates and disengages from the positioning block 28 and presses down, the sharp part 23 of the activation mechanism 2 damages the diaphragm 11, and the degree of damage to the diaphragm 11 is aggravated by rotating the activation rod 22. After the upper chamber 12 and the lower chamber 13 are connected, the solvent and the drug powder are mixed. At this time, the container 1 needs to be shaken thoroughly to ensure that the drug and the solvent are completely and evenly mixed. Then, the mixed skin test solution can be drawn by inserting the syringe needle into the drug solution extraction port 14.

[0030] The above description of the disclosed embodiments enables those skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention; therefore, the present invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

[0031] Although this document frequently uses reference numerals from the accompanying drawings, such as tank 1, partition membrane 11, upper chamber 12, lower chamber 13, liquid extraction port 14, guide strip 15, activation component 2, connecting seat 21, activation rod 22, sharp part 23, annular cover 24, slot 241, push rod 25, connecting channel 26, sealing ring 27, positioning block 28, and mating block 29, the possibility of using other terms is not excluded. These terms are used merely for the convenience of describing and explaining the essence of this utility model; interpreting them as any additional limitation would contradict the spirit of this utility model.

Claims

1. A ready-to-use skin test solution preparation container, characterized in that, include: A sealed container (1) is divided inside by a partition membrane (11) into an upper chamber (12) for containing drugs and a lower chamber (13) for containing solvents. A liquid extraction port (14) is provided on the tank (1) and is connected to the lower chamber (13); An activation component (2) is disposed on the tank (1) and communicates with the upper chamber (12). The activation component (2) includes an activation rod (22) movable relative to the tank (1). The end of the activation rod (22) is provided with a sharp part (23) for piercing the septum (11).

2. The instant skin test solution preparation container according to claim 1, characterized in that, The activation component (2) further includes a connecting seat (21) fixedly connected to the tank (1), the connecting seat (21) is provided with a channel for the activation rod (22) to pass through, and a sealing structure is provided between the activation rod (22) and the connecting seat (21).

3. The instant-mixing, ready-to-use skin test solution preparation container according to claim 2, characterized in that, A positioning structure is provided between the activation rod (22) and the tank (1) or the connecting seat (21) to prevent the activation rod (22) from moving accidentally.

4. The instant-mixing, ready-to-use skin test solution preparation container according to claim 3, characterized in that, The positioning structure includes a positioning block (28) disposed on the inner wall of the channel of the connecting seat (21) and a mating block (29) disposed on the outer wall of the activation rod (22). When the activation rod (22) is in the initial position, the mating block (29) abuts against the positioning block (28).

5. The instant-mixing, ready-to-use skin test solution preparation container according to claim 1, characterized in that, The activation lever (22) moves by pressing or rotating a combination of pressing and rotating.

6. The instant-mixing, ready-to-use skin test solution preparation container according to claim 1, characterized in that, The pointed part (23) is an eccentrically arranged needle-shaped structure or a ring-shaped sawtooth structure.

7. The instant skin test solution preparation container according to claim 1, characterized in that, The liquid extraction port (14) is made of an elastic sealing material that can be pierced by a syringe needle.

8. The instant-mixing, ready-to-use skin test solution preparation container according to claim 7, characterized in that, The liquid extraction port (14) and the activation component (2) are respectively located at opposite ends of the tank (1).

9. A ready-to-use skin test solution preparation container according to any one of claims 1 to 8, characterized in that, The container (1) is made of a transparent or translucent medical-grade polymer material.

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