An antibody reagent management storage device

CN224830224UActive Publication Date: 2026-10-09THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIV
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Patent Information

Application Number
CN202522464708.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-11-20
Publication Date
2026-10-09
Estimated Expiration
2035-11-20

AI Technical Summary

Technical Problem

在实验操作中,反复从冰箱中取出、长时间置于室温环境,会显著缩短其有效期,导致实验失败和巨大经济损失

Benefits of technology

[0016]采用上述技术方案后,本实用新型的的储存盒体上设有若干第一放置孔,可以放置较大规格,例如6ml的抗体试剂,抗体试剂主体可收纳于上腔室,并受第一放置孔限位固定,抗体试剂顶部伸出第一放置孔,以方便取放;而当需要放置小规格,例如3ml的抗体试剂时,可以将调节卡板安装于储存盒体顶面,使小规格的抗体试剂可以依次穿过第二放置孔和第一放置孔后收纳于上腔室内,并受第二放置孔限位,防止倾倒泄露,以此利用一个储存盒体,即可实现常用两种规格的抗体试剂的收纳存放,相比现有多个不同架子分别存放不同规格的抗体试剂,本实用新型可以充分利用空间。

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Abstract

The application discloses an antibody reagent management storage device, which comprises a storage box body, an adjusting card plate detachably mounted on the storage box body, a partition plate arranged in the storage box body, a cold source arranged in a lower chamber of the storage box body, a plurality of first placing holes arranged in a horizontal and vertical array on a top surface of the storage box body, the first placing holes being communicated with the upper chamber, the adjusting card plate being arranged above one row of the first placing holes on the top surface of the storage box body, a plurality of second placing holes arranged on the adjusting card plate and matched with the first placing holes, and the second placing holes being smaller than the first placing holes in diameter, the second placing holes and the first placing holes being used for accommodating antibody reagents of different sizes.
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Description

Technical Field

[0001] This utility model relates to the technical field of medical devices, and in particular to an antibody reagent management and storage device. Background Technology

[0002] High-quality monoclonal antibody reagents are extremely expensive, costing thousands or even tens of thousands of dollars per milligram. The vast majority of antibodies require cryopreservation to maintain their biological activity. Repeatedly removing them from the refrigerator and leaving them at room temperature for extended periods significantly shortens their shelf life, leading to experimental failures and substantial financial losses. Furthermore, frequently opening and closing the refrigerator door to search for specific antibodies not only affects the temperature stability of other samples inside the refrigerator but also increases the risk of reagent contamination and misuse.

[0003] Traditional racks have fixed slot diameters, which cannot stably hold different sizes of reagent tubes (such as 3ml and 6ml) at the same time. This results in laboratories needing to equip different racks for different sizes of reagents, which takes up space and is inconvenient to manage.

[0004] Furthermore, traditional marking methods such as markers (written directly on the rack, difficult to erase) and labels (easily detached, illegible) make reagent information difficult to identify, a significant source of experimental error. Staff need to spend a lot of time on non-core research tasks, such as finding reagents and manually checking inventory. Utility Model Content

[0005] The purpose of this invention is to provide an antibody reagent management and storage device, which has the advantages of conveniently storing reagents of different specifications and effectively ensuring the activity of antibody reagents during use, thereby improving experimental efficiency.

[0006] To achieve the above objectives, the solution of this utility model is: An antibody reagent management and storage device includes a storage box with an adjustment plate detachably mounted on the storage box; The storage box is equipped with a partition that divides the storage box into an upper chamber and a lower chamber. The lower chamber contains a cold source. The top surface of the storage box is provided with a number of first placement holes arranged in a horizontal and vertical array. The first placement holes are connected to the upper chamber. The adjustment plate extends laterally and is detachably located above one row of first placement holes on the top surface of the storage box; the adjustment plate is provided with several second placement holes that are vertically connected and aligned with each of the first placement holes, the diameter of the second placement holes being smaller than the diameter of the first placement holes, and the second placement holes and the first placement holes being used to accommodate antibody reagents of different sizes and specifications.

[0007] Furthermore, the storage box body is provided with multiple adjustment plates; each adjustment plate has a downwardly extending clamping part at both ends, and the two clamping parts are respectively clamped into the slots provided on the two transverse side walls of the storage box body, and the side of the clamping part away from the slot is provided with a protruding handle.

[0008] Furthermore, the lower front part of the storage box is provided with a lower opening that connects to the lower chamber, and a lower drawer is removably installed at the lower opening, which is used to accommodate the cold source.

[0009] Furthermore, the top of the storage box is provided with an opening that connects to the upper chamber. A placement rack is detachably provided at the opening. The placement rack has a placement plate that closes the opening. The placement plate is provided with the first placement hole. The bottom of the placement plate is provided with several support feet that extend downward and abut against the partition.

[0010] Furthermore, a sensor bracket is provided below the first placement hole, and a weighing sensor located directly below the first placement hole is installed on the sensor bracket; an indicator light is provided on one side of each first placement hole on the top surface of the storage box, and the indicator light is electrically connected to the weighing sensor below the corresponding first placement hole.

[0011] Furthermore, the second placement hole is concentrically arranged with the first placement hole.

[0012] Furthermore, the top surface of the storage box is provided with a horizontally extending whiteboard on one side of the first placement hole in each row, and a transparent film is detachably provided on the whiteboard.

[0013] Furthermore, the partition is provided with perforated holes that connect the upper chamber and the lower chamber; the storage box is made of heat-insulating material.

[0014] Furthermore, there are at least two storage boxes; the storage boxes are stacked one on top of the other with a gap between them, and a support bracket is provided between adjacent storage boxes.

[0015] Furthermore, the support bracket consists of four support rods distributed at the four corners of the storage box. The support rods have tenons protruding from the top and bottom respectively. The four corners of the top and bottom surfaces of the storage box are respectively provided with mortises for the tenons to be inserted and fitted.

[0016] After adopting the above technical solution, the storage box of this utility model is provided with several first placement holes, which can hold larger sizes, such as 6ml antibody reagents. The main body of the antibody reagent can be stored in the upper chamber and fixed by the first placement holes. The top of the antibody reagent extends out of the first placement holes for easy access. When it is necessary to store smaller sizes, such as 3ml antibody reagents, an adjustment plate can be installed on the top surface of the storage box, so that the smaller antibody reagent can pass through the second placement hole and the first placement hole in sequence and be stored in the upper chamber, and is fixed by the second placement hole to prevent tipping and leakage. In this way, two commonly used sizes of antibody reagents can be stored in one storage box. Compared with the existing multiple different shelves for storing different sizes of antibody reagents, this utility model can make full use of space.

[0017] Meanwhile, since the storage box has a lower chamber for storing a cold source, the experimenter can remove the entire storage box from the refrigerator when using it. At room temperature, the cold source in the lower chamber of the storage box can provide a low-temperature environment for the upper chamber, so that the antibody reagents inside can maintain their activity for a long time and avoid inactivation and unnecessary loss. It can also reduce the frequency of opening and closing the refrigerator, making the experiment more convenient and improving experimental efficiency. Attached Figure Description

[0018] Figure 1 This is a perspective view of an embodiment of the present utility model; Figure 2 This is an exploded view of an embodiment of the present utility model; Figure 3 This is a cross-sectional view of an embodiment of the present utility model; Figure 4 This is a top view of an embodiment of the present utility model; Figure 5 This is a schematic diagram of the stacking process according to an embodiment of the present utility model; Figure 6 This is a stacked front view of an embodiment of the present utility model.

[0019] Labeling: Storage box 1, partition 11, perforation 111, upper chamber 12, lower chamber 13, first placement hole 14, slot 15, lower opening 16, lower drawer 17, open opening 18, placement rack 19, placement plate 191, support foot 192, white board 20, adjusting plate 2, second placement hole 21, locking part 22, handle 221, antibody reagent 3, sensor bracket 4, base plate 41, connecting rod 42, weighing sensor 5, indicator light 6, support bracket 7, support rod 71, tenon 72, mortise 73. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. The components of the embodiments of this application described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0021] like Figures 1 to 6 As shown, an antibody reagent management and storage device according to this embodiment includes a storage box 1, on which an adjustment plate 2 is detachably installed.

[0022] The storage box 1 is provided with a partition 11 inside, which divides the storage box 1 into an upper chamber 12 and a lower chamber 13. The lower chamber 13 contains a cold source (not shown in the figure). The top surface of the storage box 1 is provided with a number of first placement holes 14 arranged in a horizontal and vertical array, and the first placement holes 14 are connected to the upper chamber 12.

[0023] The adjustment plate 2 extends laterally and is detachably located above one row of first placement holes 14 distributed laterally on the top surface of the storage box 1; the adjustment plate 2 is provided with several second placement holes 21 that are vertically connected and aligned with each of the first placement holes 14, the diameter of the second placement hole 21 is smaller than the diameter of the first placement hole 14, and the second placement hole 21 and the first placement hole 14 are respectively used to accommodate antibody reagents 3 of different sizes and specifications.

[0024] Therefore, the storage box 1 of this embodiment is provided with several first placement holes 14, which can hold larger sizes, such as 6ml of antibody reagent 3. The main body of antibody reagent 3 can be stored in the upper chamber 12 and fixed by the first placement holes 14. The top of antibody reagent 3 extends out of the first placement holes 14 for easy access. When it is necessary to store smaller sizes, such as 3ml of antibody reagent 3, the adjusting plate 2 can be installed on the top surface of the storage box 1, so that the smaller size of antibody reagent 3 can pass through the second placement hole 21 and the first placement hole 14 in sequence and be stored in the upper chamber 12, and be fixed by the second placement hole 21 to prevent tipping and leakage. In this way, two commonly used sizes of antibody reagent 3 can be stored using one storage box 1, making full use of space.

[0025] Meanwhile, since the storage box 1 has a lower chamber 13 for storing a cold source, the experimenter can take the entire storage box 1 out of the refrigerator when using it. At room temperature, the cold source in the lower chamber 13 of the storage box 1 can provide a low temperature environment for the upper chamber 12, so that the antibody reagents 3 inside can maintain their activity for a long time and not be inactivated, thus avoiding unnecessary losses. It can also reduce the frequency of opening and closing the refrigerator, making the experiment more convenient and improving experimental efficiency.

[0026] In this embodiment, the storage box 1 may be provided with six rows and eight columns of forty-eight first placement holes 14, and the storage box 1 may also be provided with multiple adjustment plates 2, each of which can be installed and placed as needed.

[0027] like Figure 2 As shown, specifically, the two ends of the adjustment plate 2 may each have a downwardly extending clamping part 22. The two clamping parts 22 are respectively clamped and fitted into the slots 15 provided on the two transverse side walls of the storage box body 1. The side of the clamping part 22 away from the slot 15 is provided with a protruding handle 221.

[0028] By setting the locking part 22 and the slot 15 to cooperate, the adjusting plate 2 can be easily snapped into place. The slot 15 also facilitates the positioning of the adjusting plate 2, so that the second placement hole 21 of the adjusting plate 2 can be aligned with the first placement hole 14. At the same time, the locking part 22 is provided with a handle 221, which can facilitate the installation and removal of the adjusting plate 2.

[0029] In this embodiment, the adjustment plate 2 is arranged horizontally to the left and right, but it can also be arranged vertically to the front and back, and is not limited to this embodiment.

[0030] In this embodiment, the lower front part of the storage box 1 is provided with a lower opening 16 that communicates with the lower chamber 13. A lower drawer 17 is installed at the lower opening 16 and is used to accommodate the cold source, which may be ice, ice packs, etc.

[0031] By setting up the lower drawer 17, it is easy to place and replace the cold source without interfering with the antibody reagents 3 in the upper chamber 12.

[0032] In this embodiment, the partition 11 may be provided with a perforated hole 111, which connects the upper chamber 12 and the lower chamber 13 to facilitate the flow of cold air to keep the upper chamber 12 cold.

[0033] Meanwhile, the storage box 1 in this embodiment can be made of heat-insulating material to improve the cold-keeping effect.

[0034] In this embodiment, the top of the storage box 1 is provided with an opening 18 that communicates with the upper chamber 12. A placement rack 19 is detachably provided at the opening 18. The placement rack 19 has a placement plate 191 that closes the opening 18. The placement plate 191 is provided with the first placement hole 14. The bottom of the placement plate 191 is provided with a plurality of support feet 192 that extend downward and abut against the partition plate 11.

[0035] Therefore, by replacing the placement rack 19 with the first placement hole 14 of different sizes, it can be adapted to various specifications of antibody reagents 3, thereby improving the versatility of the storage box 1.

[0036] See Figure 3 In order to facilitate the management and monitoring of reagent inventory, in this embodiment, a sensor bracket 4 is provided below the first placement hole 14, and a weighing sensor 5 located directly below the first placement hole 14 is installed on the sensor bracket 4; an indicator light 6 is provided on one side of each first placement hole 14 on the top surface of the storage box 1, and the indicator light 6 is electrically connected to the weighing sensor 5 below the corresponding first placement hole 14.

[0037] Therefore, the weighing sensor 5 can weigh the antibody reagent 3. Through program settings, when the weighing sensor 5 detects that the weight of the antibody reagent 3 is lower than a preset value, the program determines that the remaining antibody reagent 3 is insufficient or exhausted, and triggers the indicator light 6 to illuminate or flash. This informs the experimenter of the inventory status of the antibody reagent 3 in the storage box 1, allowing the experimenter to promptly determine whether the antibody reagent 3 is sufficient and can last until the end of the experiment. If insufficient inventory is found, it can be replenished in time to avoid experimental interruption due to insufficient antibody reagent 3, thereby improving experimental efficiency and ensuring accurate and reliable experimental results.

[0038] Compared to manual handling of antibody reagent 3 by laboratory personnel and visual judgment of the remaining amount, weighing to detect the remaining amount results in more accurate and efficient detection, and avoids any omissions in the detection.

[0039] The weighing sensor 5 can be based on existing technology. The sensor bracket 4 can include a base plate 41 and a plurality of connecting rods 42 surrounding and connecting the outer periphery of the base plate 41 and the lower edge of the first placement hole 14. The weighing sensor 5 can be placed and fixed on the base plate 41.

[0040] In this embodiment, the second placement hole 21 can be concentrically set with the first placement hole 14 so that antibody reagents 3 of different specifications can be aligned with the weighing sensor 5.

[0041] Furthermore, in this embodiment, the top surface of the storage box 1 may also be provided with a horizontally extending white board 20 on one side of each row of first placement holes 14, and the white board 20 is detachably provided with a transparent film.

[0042] By adding a whiteboard 20 made of hard plastic or other materials, it is easy to write or erase information such as the name and expiration date of the corresponding antibody reagent 3. Moreover, by adding a transparent plastic film with slight adhesion that can be easily removed, the text can be covered and protected, preventing the text on the whiteboard 20 from being accidentally smudged or erased, thus ensuring that the information is clear and accurate.

[0043] For example Figure 5 and Figure 6As shown, in this embodiment, there are at least two storage boxes 1; the storage boxes 1 are stacked one on top of the other with a gap between them, and a support bracket 7 is provided between adjacent storage boxes 1.

[0044] By setting up the support bracket 7, the storage box 1 can be easily stacked and stored, which can further make full use of the space inside the refrigerator.

[0045] Specifically, the support bracket 7 can be four support rods 71 ​​distributed at the four corners of the storage box 1. The support rods 71 ​​have tenons 72 protruding from the top and bottom respectively. The four corners of the top and bottom surfaces of the storage box 1 are respectively provided with mortises 73 for the tenons 72 to be inserted and fitted.

[0046] Therefore, the mortise and tenon structure ensures the stability of the stacked storage boxes 1 and improves the reliability of the device.

[0047] The above description is merely a preferred embodiment of this utility model. The protection scope of this utility model is not limited to the above embodiments. All technical solutions falling within the scope of this utility model's concept are protected by this utility model. It should be noted that for those skilled in the art, equivalent changes and modifications without departing from the principle of this utility model should still fall within the protection scope of this utility model.

[0048] In the description of the embodiments of this application, it should be understood that the indicated orientations or positional relationships are based on the orientations or positional relationships shown in the accompanying drawings, or the orientations or positional relationships commonly used when the product is in use, or the orientations or positional relationships commonly understood by those skilled in the art. These are only for the convenience of describing this application and simplifying the description, and are not intended to indicate or imply that the device or component referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application. In the description of this application, "a plurality of" and "several" mean two or more, unless otherwise explicitly specified.

Claims

1. An antibody reagent management and storage device, characterized in that: Includes a storage box, on which an adjustment plate is detachably installed; The storage box is equipped with a partition that divides the storage box into an upper chamber and a lower chamber. The lower chamber contains a cold source. The top surface of the storage box is provided with a number of first placement holes arranged in a horizontal and vertical array. The first placement holes are connected to the upper chamber. The adjustment plate extends laterally and is detachably located above one row of first placement holes on the top surface of the storage box; the adjustment plate is provided with several second placement holes that are vertically connected and aligned with each of the first placement holes, the diameter of the second placement holes being smaller than the diameter of the first placement holes, and the second placement holes and the first placement holes being used to accommodate antibody reagents of different sizes and specifications.

2. The antibody reagent management and storage device according to claim 1, characterized in that: The storage box is provided with multiple adjustment plates; each adjustment plate has a downwardly extending clamping part at both ends, and the two clamping parts are respectively clamped into the slots provided on the two transverse side walls of the storage box. The side of the clamping part away from the slot is provided with a protruding handle.

3. The antibody reagent management and storage device according to claim 1, characterized in that: The storage box has a lower opening at the lower front side that connects to the lower chamber. A lower drawer is installed at the lower opening and is used to house the cold source.

4. The antibody reagent management and storage device according to claim 1, characterized in that: The top of the storage box is provided with an opening that connects to the upper chamber. A placement rack is detachably installed at the opening. The placement rack has a placement plate that closes the opening. The placement plate is provided with the first placement hole. The bottom of the placement plate is provided with several support feet that extend downward and abut against the partition.

5. The antibody reagent management and storage device according to claim 1, characterized in that: A sensor bracket is provided below the first placement hole, and a weighing sensor located directly below the first placement hole is installed on the sensor bracket; an indicator light is provided on one side of each first placement hole on the top surface of the storage box, and the indicator light is electrically connected to the weighing sensor below the corresponding first placement hole.

6. The antibody reagent management and storage device according to claim 1, characterized in that: The second placement hole is concentrically arranged with the first placement hole.

7. The antibody reagent management and storage device according to claim 1, characterized in that: The top surface of the storage box is provided with a horizontally extending whiteboard on one side of the first placement hole in each row, and the whiteboard is provided with a detachable transparent film.

8. The antibody reagent management and storage device according to claim 1, characterized in that: The partition has perforations that connect the upper and lower chambers; the storage box is made of heat-insulating material.

9. The antibody reagent management and storage device according to claim 1, characterized in that: The storage box consists of at least two boxes; the storage boxes are stacked one on top of the other with a gap between them, and a support bracket is provided between adjacent storage boxes.

10. An antibody reagent management and storage device according to claim 9, characterized in that: The support bracket consists of four support rods distributed at the four corners of the storage box. The support rods have tenons protruding from the top and bottom. The four corners of the top and bottom surfaces of the storage box are provided with mortises for the tenons to be inserted and fitted.