An immunochromatographic test kit for the identification of biological products
Patent Information
- Application Number
- CN202521973419.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-15
- Publication Date
- 2026-10-09
- Estimated Expiration
- 2035-09-15
AI Technical Summary
[0002]免疫层析检测试剂盒是基于抗原与抗体特异性免疫反应的快速检测技术,以硝酸纤维素膜为固相载体,通过毛细管作用驱动样本在膜条上流动,实现目标物的捕获与显色;该技术起源于20世纪70年代,融合了层析分离与免疫检测原理,经数十年发展已成为生物制品鉴定的核心工具之一,广泛应用于疫苗成分分析、重组蛋白纯度检测、抗体效价测定等场景;早期以胶体金为主要标记物,凭借肉眼可见的显色反应实现定性检测,近年来逐步发展出荧光微球、量子点等新型标记体系,推动检测性能提升;然而现有的装置也存在明显的不足,早期的免疫层析检测试剂盒是一体化一次性用品,由检测试纸与外壳组成,例如:一体化一次性用品材料消耗过多,浪费材料;原设备为即拿即用,试剂直接安装在盒体内,大部分暴露空气中,密封性较差,易于对试纸造成污染,影响检测结果;因此,需对上述问题件进行解决处理
[0010]与现有技术相比,本实用新型的有益效果是:本实用新型通过放置板与限位块的限位配合,便于对检测试纸的固定,提高了检测试纸固定的便捷性,进而能够实现降低检测试纸被污染的功能,再通过移动块与夹板的铰接配合,便于放置板的灵活更换,提高了盒体的使用效率,进而能够实现节省材料的功能,最终解决了检测使用过程中使内部试纸造成污染与材料浪费的问题;本装置结构简单,使用过程中只需更换放置板即可,大幅度提高了材料的使用率,使用方便,减少污染情况。
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Figure CN224830271U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of testing reagents and equipment, and in particular to an immunochromatographic detection kit for the identification of biological products. Background Technology
[0002] Immunochromatographic assay kits are rapid detection technologies based on antigen-antibody specific immune reactions. Using nitrocellulose membranes as solid-phase carriers, samples flow across the membrane strip via capillary action, achieving target analyte capture and color development. Originating in the 1970s, this technology integrates chromatographic separation and immunoassay principles. After decades of development, it has become a core tool for bioproduct identification, widely used in vaccine component analysis, recombinant protein purity detection, and antibody titer determination. Early kits primarily used colloidal gold as the main label, achieving qualitative detection through visible colorimetric reactions. In recent years, novel labeling systems such as fluorescent microspheres and quantum dots have been developed, improving detection performance. However, existing devices also have significant shortcomings. Early immunochromatographic assay kits were integrated disposable items, consisting of test strips and a casing. For example, these integrated disposable items consumed excessive materials, leading to waste. Furthermore, the original equipment was ready to use immediately, with reagents directly installed inside the kit, leaving most of the reagents exposed to air, resulting in poor sealing and easy contamination of the test strips, affecting test results. Therefore, these problems need to be addressed. Utility Model Content
[0003] The purpose of this invention is to address the shortcomings of existing technologies by proposing an immunochromatographic assay kit for the identification of biological products.
[0004] To achieve the above objectives, the present invention adopts the following technical solution: an immunochromatographic assay kit for the identification of biological products, comprising a box body, an installation groove on the rear end face of the box body, second guide rails on both sides of the inner wall of the installation groove, a placement plate in the installation groove, sliders on both sides of the placement plate, the sliders sliding in the second guide rails, and a connecting component between the box body and the placement plate.
[0005] Preferably, the connecting assembly includes a connecting shaft that is horizontally installed in the middle of the front end inside the box, a torsion spring is installed on the outside of the connecting shaft, one end of the torsion spring is fixedly connected to the connecting shaft, and an L-shaped positioning rod is installed on the other end of the torsion spring.
[0006] Preferably, a positioning plate is provided horizontally inside the box body, and a guide rail groove is opened in the middle of the positioning plate. The groove inside the guide rail groove is higher at one end and lower at the other end. The other end of the L-shaped positioning rod is placed in the groove of the guide rail groove. Moving blocks are installed on both sides of the positioning plate, and an L-shaped clamping plate is movably hinged to the far end of the two moving blocks.
[0007] Preferably, the box body has a second limiting groove on both sides inside, and a first limiting groove is formed at the front end of the two second limiting grooves facing each other, and the L-shaped clamp abuts against the first limiting groove.
[0008] Preferably, an observation window is installed at the front end of the top of the box body, a drip outlet is installed at the rear end of the top surface of the placement plate, and a placement groove is opened on the rear end surface of the placement plate; an observation groove is opened on the top surface of the placement plate, and an L-shaped sealing plate is movably hinged to the rear end of the placement plate.
[0009] Preferably, the inner walls on both sides of the placement plate are provided with first guide rails, and the two outer ends of the L-shaped sealing plate are fixed with limit blocks.
[0010] Compared with the prior art, the beneficial effects of this utility model are as follows: This utility model facilitates the fixing of test strips through the limiting cooperation between the placement plate and the limiting block, improving the convenience of fixing test strips and thus reducing the contamination of test strips. Furthermore, the hinged cooperation between the moving block and the clamping plate facilitates the flexible replacement of the placement plate, improving the utilization efficiency of the box and thus saving materials. Ultimately, it solves the problem of internal test strip contamination and material waste during testing. This device has a simple structure, and only the placement plate needs to be replaced during use, which greatly improves the utilization rate of materials, is convenient to use, and reduces contamination. Attached Figure Description
[0011] The accompanying drawings, which are included to provide a further understanding of the present invention and form part of this application, illustrate exemplary embodiments of the present invention and, together with the description thereof, serve to explain the present invention and do not constitute an undue limitation thereof. In the drawings: Figure 1 This is a schematic diagram of the overall structure proposed in this utility model; Figure 2 This is a side-view stereoscopic result diagram of the present invention; Figure 3 This is a schematic diagram of the cross-sectional structure of the torsion spring proposed in this utility model; Figure 4 This is a schematic diagram of the overall cross-sectional structure proposed in this utility model; Figure 5 The present utility model proposes Figure 3 Enlarged schematic diagram of the structure at part A in the middle; Figure 6 The present utility model proposes Figure 4 Enlarged schematic diagram of the structure of part B in the middle; Figure 7 The present utility model proposes Figure 2 Enlarged schematic diagram of the structure at part C.
[0012] The numbers in the diagram are: 1. Box body; 2. Placement plate; 3. Drip outlet; 4. Observation window; 5. L-shaped sealing plate; 6. Limiting block; 7. First guide rail; 8. L-shaped clamp; 9. Moving block; 10. Torsion spring; 11. Connecting shaft; 12. Guide rail groove; 13. Second guide rail; 14. First limiting groove; 15. Second limiting groove. Detailed Implementation
[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.
[0014] Example: See Figures 1 to 7 An immunochromatographic assay kit for identifying biological products according to this utility model includes a box body 1, which facilitates the connection of the entire device; a mounting groove is provided on the rear end face of the box body 1, and second guide rails 13 are provided on both sides of the inner wall of the mounting groove, and a placement plate 2 is provided in the mounting groove, which facilitates the placement of test strips; sliders are installed on both sides of the placement plate 2, and the sliders slide within the second guide rails 13; a connecting component is provided between the box body 1 and the placement plate 2, which facilitates the movement of the placement plate 2 through the second guide rails 13.
[0015] In this utility model, the connecting assembly includes a connecting shaft 11 horizontally installed in the middle of the front end inside the box body 1. A torsion spring 10 is installed on the outside of the connecting shaft 11, which facilitates the installation of the torsion spring 10. One end of the torsion spring 10 is fixedly connected to the connecting shaft 11, which facilitates the provision of elastic force. An L-shaped positioning rod is installed on the other end of the torsion spring 10. A positioning plate is horizontally provided inside the box body 1. A guide rail groove 12 is opened in the middle of the positioning plate, which facilitates the movement and limiting of the torsion spring 10. The groove opened inside the guide rail groove 12 has one end higher than the other. The other end of the L-shaped positioning rod is placed in the groove of the guide rail groove 12. Moving blocks 9 are installed on both sides of the positioning plate, which facilitates the use of the clamping device. An L-shaped clamping plate 8 is movably hinged to the distal ends of the two moving blocks 9, which facilitates the clamping of the placement plate 2. The box body 1 has openings on both sides. A second limiting groove 15 is provided, and a first limiting groove 14 is opened at the front end of the two opposing second limiting grooves 15. The L-shaped clamp 8 can be moved inward through the second limiting groove 15. The L-shaped clamp 8 abuts in the first limiting groove 14, and the L-shaped clamp 8 can be moved outward through the first limiting groove 14. An observation window 4 is installed at the front end of the top of the box body 1, and the detection structure can be observed through the observation window 4. A drip nozzle 3 is installed at the rear end of the top surface of the placement plate 2, and the detection liquid can be dripped through the drip nozzle 3. A placement groove is opened at the rear end of the placement plate 2. An observation groove is opened at the top surface of the placement plate 2, and an L-shaped sealing plate 5 is movably hinged at the rear end of the placement plate 2. A first guide rail 7 is opened on both inner walls of the placement plate 2, and the movement of the limiting block 6 can be facilitated through the first guide rail 7. The two outer ends of the L-shaped sealing plate 5 are fixed with the limiting block 6, and the limiting block 6 can be used to limit the L-shaped sealing plate 5.
[0016] Working principle: When using this invention, specifically the immunochromatographic assay kit for biological product identification, the test strip is first placed in the placement plate 2. Then, the L-shaped sealing plate 5, hinged to the rear end of the placement plate 2, is raised, causing the limiting blocks 6 fixed to both ends of the outer side of the L-shaped sealing plate 5 to move along the first guide rails 7 on the inner walls of both sides of the placement plate 2. When the limiting blocks 6 reach the bottom of the first guide rails 7, they lock, thus stably fixing the test strip onto the placement plate 2. Subsequently, the placement plate 2 is pushed, causing it to move along the box body via sliders installed on both sides. 1. The second guide rails 13 on both sides of the inner wall of the mounting groove move inward. When the placement plate 2 abuts against the moving blocks 9 installed on both sides of the positioning plate inside the box 1, the torsion spring 10 on the outside of the connecting shaft 11 horizontally installed in the middle of the front end inside the box 1 will move along the guide rail groove 12 opened in the middle of the positioning plate. During this process, one side of the L-shaped clamping plate 8, which is movably hinged to the far end of the moving block 9, moves from the first limiting groove 14 opened at the front end opposite to the second limiting groove 15 to the second limiting groove 15, while the other side clamps and fixes the placement plate 2 by hinge rotation. When the placement plate 2 moves to the middle position of the guide rail groove 12, the fixing operation of the placement plate 2 is completed. At this time, the liquid to be tested is dripped into the drip port 3 installed at the rear end of the top surface of the placement plate 2. After waiting for a period of time, the test result can be viewed through the observation window 4 installed at the front end of the top surface of the box body 1. After the test is completed, push the placement plate 2 again. The torsion spring 10 will move along the upper end of the guide rail groove 12 due to its own elasticity, which will drive the placement plate 2 to move outward. At the same time, one side of the L-shaped clamp 8 moves from the second limiting groove 15 back into the first limiting groove 14, and the other side releases its clamping on the placement plate 2. Finally, the placement plate 2 is taken out and replaced as a whole, and the next round of testing can be carried out.
[0017] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.
Claims
1. An immunochromatographic assay kit for the identification of biological products, comprising a housing (1), characterized in that: The rear end face of the box (1) is provided with an installation groove, and the inner walls of the installation groove are provided with second guide rails (13) on both sides. The installation groove is provided with a placement plate (2), and the placement plate (2) is provided with sliders on both sides. The sliders slide in the second guide rails (13). A connecting component is provided between the box (1) and the placement plate (2).
2. The immunochromatographic assay kit for identifying biological products according to claim 1, characterized in that: The connecting assembly includes a connecting shaft (11) that is horizontally installed in the middle of the front end inside the box (1). A torsion spring (10) is installed on the outside of the connecting shaft (11). One end of the torsion spring (10) is fixed to the connecting shaft (11), and an L-shaped positioning rod is installed on the other end of the torsion spring (10).
3. The immunochromatographic assay kit for the identification of biological products according to claim 2, characterized in that: The box body (1) has a horizontally positioned plate inside. The center of the positioning plate is opened in the guide rail groove (12). The groove inside the guide rail groove (12) is higher at one end and lower at the other end. The other end of the L-shaped positioning rod is placed in the groove of the guide rail groove (12). Moving blocks (9) are installed on both sides of the positioning plate. The two moving blocks (9) are movably hinged to each other with an L-shaped clamp (8).
4. The immunochromatographic assay kit for the identification of biological products according to claim 3, characterized in that: The box body (1) has a second limiting groove (15) on both sides inside. The two second limiting grooves (15) have a first limiting groove (14) at their front ends opposite each other. The L-shaped clamp (8) abuts against the first limiting groove (14).
5. The immunochromatographic assay kit for identifying biological products according to claim 1, characterized in that: The box body (1) has an observation window (4) installed at the front end of the top surface, the placement plate (2) has a drip port (3) installed at the rear end of the top surface, and the placement plate (2) has a placement groove on the rear end surface; the placement plate (2) has an observation groove on the top surface, and the placement plate (2) has an L-shaped sealing plate (5) that is movably hinged to the rear end.
6. An immunochromatographic assay kit for the identification of biological products according to claim 5, characterized in that: The inner walls on both sides of the placement plate (2) are provided with first guide rails (7), and the two outer ends of the L-shaped sealing plate (5) are fixed with limit blocks (6).