Automatic waste liquid treatment and recovery device of liquid chromatograph-mass spectrometer

Abstract

The utility model discloses a kind of waste liquid automatic treatment recovery devices of liquid chromatography mass spectrometer, belong to liquid chromatography mass spectrometer technical field.This kind of waste liquid automatic treatment recovery devices of liquid chromatography mass spectrometer, including pretreatment mechanism and separation mechanism, pretreatment mechanism includes adjusting box, the upper end of adjusting box is equipped with waste liquid tank, the inside of waste liquid tank is equipped with several waste liquid cavities, the side of adjusting box is equipped with acid tank and lye tank respectively, the bottom end of adjusting box is equipped with connecting pipe;Separation mechanism includes separation tank, the top of separation tank is connected with the bottom end of adjusting box, the bottom end of separation tank is equipped with purification tank, the inside bottom end side of separation tank is equipped with separation jar, heating jacket is equipped on the outside of separation jar, the top of separation jar is connected with the bottom end of connecting pipe, the bottom end of separation jar is equipped with drain pipe, the bottom end of drain pipe is connected with the top of purification tank, the utility model, can effectively improve the practicality of waste liquid automatic treatment recovery device.

Description

Technical Field

[0001] This utility model relates to the field of liquid chromatography-mass spectrometry (LC-MS) technology, specifically to an automatic waste liquid treatment and recovery device for LC-MS. Background Technology

[0002] Liquid chromatography-mass spectrometry (LC-MS) is an analytical instrument that combines the high-efficiency separation capability of liquid chromatography with the high-sensitivity detection capability of mass spectrometry. It is widely used in fields such as medicine, environmental protection, and food.

[0003] Based on the above, the inventors have discovered the following problems: the treatment of waste liquid from liquid chromatography-mass spectrometry instruments is mostly carried out by manual collection and unified transportation, which is inefficient and requires staff to frequently check the liquid level of the waste liquid collection container and replace it, increasing labor costs; secondly, leakage and volatilization are prone to occur during the waste liquid collection process, posing a potential threat to the health of operators.

[0004] Therefore, in view of this, we have studied and improved the existing structure and its shortcomings, and provided an automatic waste liquid treatment and recovery device for liquid chromatography-mass spectrometry, in order to achieve a more practical purpose. Utility Model Content

[0005] The purpose of this invention is to provide an automatic waste liquid treatment and recovery device for liquid chromatography-mass spectrometry (LC-MS) instruments, in order to solve the problem mentioned in the background art that the treatment of waste liquid from LC-MS instruments is mostly carried out by manual collection and unified transportation and treatment.

[0006] In view of the above problems, the technical solution proposed by this utility model is as follows:

[0007] An automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry (LC-MS) instrument includes a pretreatment mechanism and a separation mechanism. The pretreatment mechanism includes a regulating tank, with a waste liquid tank installed at its upper end. The waste liquid tank has several waste liquid chambers inside. An acid tank and an alkali tank are installed on one side of the regulating tank, and a connecting pipe is installed at the bottom of the regulating tank. The separation mechanism includes a separation tank, with its top end connected to the bottom end of the regulating tank. A purification tank is installed at the bottom end of the separation tank. A separation vessel is installed on one side of the bottom of the separation tank, with a heating jacket covering its outer side. The top end of the separation vessel is connected to the bottom end of the connecting pipe. A drain pipe is provided at the bottom end of the separation vessel, and its bottom end is connected to the top end of the purification tank. A first solenoid valve is installed inside the drain pipe. A flow equalization plate is installed at the upper end of the purification tank, and an activated carbon filter layer is installed at the bottom end of the flow equalization plate inside the purification tank. A drain pipe is inserted into the bottom end of the purification tank.

[0008] Furthermore, each waste liquid chamber is equipped with a first liquid level sensor on its inner side, a filter screen is provided at the upper end of each waste liquid chamber, and a connecting pipe communicating with the regulating tank is provided at the bottom end of each waste liquid chamber, with a second electromagnetic valve provided inside the connecting pipe.

[0009] The beneficial effects of adopting the above-mentioned further solution are that the first liquid level sensor inside the waste liquid chamber can monitor the amount of waste liquid in the chamber in real time to prevent waste liquid from overflowing; the upper filter screen can filter solid impurities in the waste liquid to prevent blockage of the connecting pipe and subsequent pipes; the lower connecting pipe, in conjunction with the second solenoid valve, can accurately control the timing and dosage of waste liquid delivered from each waste liquid chamber to the regulating tank, facilitating pH adjustment in the regulating tank.

[0010] Furthermore, a cover is installed at the top of the waste liquid tank, and an inlet pipe is installed on the cover at the top of each of the several waste liquid chambers.

[0011] The beneficial effects of adopting the above-mentioned further solution are that the cover at the top of the waste liquid tank can prevent external dust and impurities from falling into the waste liquid chamber and contaminating the waste liquid; the inlet pipe on the cover corresponds to each waste liquid chamber, which facilitates the classified introduction of different waste liquids generated by the liquid chromatography-mass spectrometry instrument, avoiding cross-contamination during manual pouring, and making the operation convenient and hygienic. Furthermore, a stirring rod is rotatably connected inside the regulating tank, a pH sensor is installed on the inner side wall of the regulating tank, a drive motor is fixedly installed at one end of the regulating tank, the drive motor is connected to the stirring rod, and a third solenoid valve is provided inside the connecting pipe.

[0012] The beneficial effects of adopting the above-mentioned further solution are that the stirring rod in the regulating tank rotates under the drive of the motor, which can make the waste liquid and acid or alkali liquid fully mixed, ensuring uniform pH adjustment and improving the pretreatment effect; the third solenoid valve in the connecting pipe can control the delivery of the pretreated waste liquid to the separation tank, and precisely control the liquid supply rhythm in conjunction with the separation process to avoid excessive or insufficient waste liquid in the separation tank; the pH sensor can monitor the pH value of the waste liquid inside the regulating tank in real time.

[0013] Furthermore, a pump is fixedly installed between the acid tank and the alkali tank. The output end of the pump is connected to the regulating box through a pipe, and the input end of the pump is fitted with an electromagnetic three-way valve. The two ends of the electromagnetic three-way valve are connected to the bottom of the acid tank and the alkali tank respectively through pipes.

[0014] The beneficial effects of adopting the above-mentioned further solution are that the pump provides power for the acid and alkali tanks to deliver acid and alkali solutions to the regulating tank, and the electromagnetic three-way valve can flexibly switch the delivery channel of acid or alkali solution, adjust the amount of acid and alkali solution added, and ensure that the pH value of the waste liquid is adjusted to the target range.

[0015] Furthermore, a gas-liquid separator is fixedly installed at one end of the separation box, and a collection tank is fixedly installed at one end of the purification box.

[0016] The beneficial effects of adopting the above-mentioned further solution are that the gas-liquid separator at one end of the separation box can separate the organic solvent gas generated during the heating of the waste liquid; the collection tank at one end of the purification box can collect the recyclable organic solution separated by the gas-liquid separator, thereby realizing resource recycling and reducing waste.

[0017] Furthermore, the input end of the gas-liquid separator is connected to the upper side of the separation tank via a pipe, and the output end of the gas-liquid separator is connected to the top of the collection tank via a pipe.

[0018] The beneficial effects of adopting the above-mentioned further solution are that the gas-liquid separator is connected to the upper end of the separation tank through a pipeline, which can extract the gas generated in the separation tank in a timely manner; the output pipeline is connected to the collection tank to ensure that the separated recyclable materials are directly introduced into the collection tank, avoiding pollution or waste caused by leakage in the middle, and improving recycling efficiency and safety.

[0019] Furthermore, several temperature sensors are vertically installed inside the heating jacket along the axis of the separation tank, and the monitoring end of the temperature sensors is in contact with the outer wall of the separation tank.

[0020] The beneficial effects of adopting the above-mentioned further solution are that several temperature sensors installed vertically along the axis of the separator inside the heating jacket can monitor the temperature at different heights of the separator in real time, avoiding incomplete separation caused by excessively high or low local temperatures; the monitoring end of the temperature sensor is attached to the outer wall of the separator to ensure accurate temperature data, providing a basis for adjusting the power of the heating jacket and realizing precise control of the waste liquid separation temperature.

[0021] Compared with the prior art, the beneficial effects of this utility model are as follows: The automatic waste liquid treatment and recovery device for liquid chromatography-mass spectrometry (LC-MS) has a pretreatment mechanism with a regulating tank that can perform pH adjustment pretreatment on the waste liquid. Several waste liquid chambers in the waste liquid tank can classify and store different types of LC-MS waste liquid, avoiding mixed contamination. In the separation mechanism, the heating jacket on the outside of the separation tank can vaporize the organic solvent in the waste liquid through heating, and the vapor of the organic solvent is separated and liquefied by a gas-liquid separator for easy collection. The unvaporized liquid enters the purification tank through the drain pipe. The flow equalization plate makes the liquid flow evenly through the activated carbon filter layer, and after adsorbing impurities, it is discharged through the drain pipe for easy recovery. The connecting pipe realizes a stable liquid supply between the regulating tank and the separation tank. The first electromagnetic valve controls the drainage rhythm. The whole device realizes the classification pretreatment, heating separation and adsorption purification of waste liquid, improves the waste liquid treatment efficiency and recycling rate, and reduces environmental pollution. Attached Figure Description

[0022] Figure 1 This is a three-dimensional structural diagram of the automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry system disclosed in this embodiment of the present invention. Figure 1 ;

[0023] Figure 2 This is a three-dimensional structural diagram of the automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry system disclosed in this embodiment of the present invention. Figure 2 ;

[0024] Figure 3 This is a three-dimensional structural diagram of the internal structure of the separation chamber of the automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry system disclosed in this embodiment of the present invention.

[0025] Figure 4 This is a front cross-sectional view of the regulating box and waste liquid tank of the automatic waste liquid treatment and recovery device for the liquid chromatography-mass spectrometry instrument disclosed in this embodiment of the present invention.

[0026] Figure 5 This is a partial front cross-sectional view of the purification chamber of the automatic waste liquid treatment and recovery device for the liquid chromatography-mass spectrometry system disclosed in this embodiment of the present invention.

[0027] In the diagram: 1. Pretreatment mechanism; 101. Regulating tank; 102. Waste liquid tank; 103. Waste liquid chamber; 104. Tank cover; 105. Inlet pipe; 106. Acid tank; 107. Alkali tank; 108. Pump; 109. Solenoid three-way valve; 110. Drive motor; 111. First liquid level sensor; 112. Stirring rod; 113. Second solenoid valve; 114. Filter screen; 115. Connecting pipe; 116. Third solenoid valve; 117. pH sensor; 2. Separation mechanism; 201. Separation tank; 202. Purification tank; 203. Collection tank; 204. Gas-liquid separator; 205. Drain pipe; 206. Separation tank; 207. Heating jacket; 208. Flow equalization plate; 209. Activated carbon filter layer; 210. First solenoid valve; 211. Drain pipe. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] Please see Figure 1 - Figure 5This utility model provides a technical solution: an automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry (LC-MS) instrument, comprising a pretreatment mechanism 1 and a separation mechanism 2. The pretreatment mechanism 1 includes a regulating tank 101, with a waste liquid tank 102 installed at the upper end of the regulating tank 101. The waste liquid tank 102 has several waste liquid chambers 103 inside. An acid tank 106 and an alkali tank 107 are respectively installed on one side of the regulating tank 101, and a connecting pipe 115 is installed at the bottom end of the regulating tank 101. The separation mechanism 2 includes a separation tank 201, with the top end of the separation tank 201 connected to the bottom end of the regulating tank 101. A clean liquid tank is installed at the bottom end of the separation tank 201. The purification box 202 and the separation box 201 are equipped with a separation tank 206 installed on one side of the bottom. The separation tank 206 is covered with a heating jacket 207. The top of the separation tank 206 is connected to the bottom of the connecting pipe 115. The bottom of the separation tank 206 is equipped with a drain pipe 211, which is connected to the top of the purification box 202. The drain pipe 211 is equipped with a first solenoid valve 210. The upper part of the purification box 202 is equipped with a flow equalization plate 208. The bottom of the flow equalization plate 208 is equipped with an activated carbon filter layer 209. The bottom of the purification box 202 is equipped with a drain pipe 205.

[0030] As an embodiment of this utility model, a first liquid level sensor 111 is installed inside each waste liquid chamber 103, a filter screen 114 is provided at the upper end of each waste liquid chamber 103, and a connecting pipe communicating with the regulating tank 101 is provided at the bottom end of each waste liquid chamber 103. A second solenoid valve 113 is provided inside each connecting pipe. The first liquid level sensor 111 inside the waste liquid chamber 103 can monitor the amount of waste liquid in the chamber in real time to prevent waste liquid from overflowing. The filter screen 114 at the upper end can filter solid impurities in the waste liquid to prevent blockage of the connecting pipe and subsequent pipes. The connecting pipe at the bottom end, in conjunction with the second solenoid valve 113, can accurately control the timing and dosage of waste liquid delivered from each waste liquid chamber 103 to the regulating tank 101, facilitating pH adjustment by the regulating tank 101.

[0031] As an embodiment of this utility model, a cover 104 is installed on the upper end of the waste liquid tank 102. An inlet pipe 105 is installed on the upper end of each of the several waste liquid chambers 103 on the cover 104. The cover 104 at the upper end of the waste liquid tank 102 can prevent external dust and impurities from falling into the waste liquid chambers 103 and contaminating the waste liquid. The inlet pipe 105 on the cover 104 corresponds to each waste liquid chamber 103, which facilitates the classified introduction of different waste liquids generated by the liquid chromatography-mass spectrometry instrument, avoids cross-contamination during manual dumping, and is convenient and hygienic to operate.

[0032] As an embodiment of this utility model, a stirring rod 112 is rotatably connected inside the regulating tank 101, a pH sensor 117 is installed on the inner side wall of the regulating tank 101, a drive motor 110 is fixedly installed at one end of the regulating tank 101, and the drive motor 110 is connected to the stirring rod 112. A third solenoid valve 116 is provided inside the connecting pipe 115. The stirring rod 112 inside the regulating tank 101 rotates under the drive of the drive motor 110, which can make the waste liquid fully mixed with the acid or alkali solution, ensuring uniform pH adjustment and improving the pretreatment effect. The third solenoid valve 116 inside the connecting pipe 115 can control the delivery of the pretreated waste liquid to the separation tank 206, and precisely control the liquid supply rhythm in conjunction with the separation process to avoid excessive or insufficient waste liquid in the separation tank 206. The pH sensor 117 can monitor the pH value of the waste liquid inside the regulating tank 101 in real time.

[0033] As an embodiment of this utility model, a pump 108 is fixedly installed between the acid tank 106 and the alkali tank 107. The output end of the pump 108 is connected to the regulating tank 101 through a pipe. The input end of the pump 108 is fitted with an electromagnetic three-way valve 109. The two ends of the electromagnetic three-way valve 109 are connected to the bottom sides of the acid tank 106 and the alkali tank 107 through pipes respectively. The pump 108 provides power for the acid and alkali tanks 106 and 107 to deliver acid and alkali solutions to the regulating tank 101. The electromagnetic three-way valve 109 can flexibly switch the delivery channel of acid or alkali solution, adjust the amount of acid and alkali solution added, and ensure that the pH value of the waste liquid is adjusted to the target range.

[0034] As an embodiment of this utility model, a gas-liquid separator 204 is fixedly installed at one end of the separation box 201, and a collection tank 203 is fixedly installed at one end of the purification box 202. The gas-liquid separator 204 at one end of the separation box 201 can separate the organic solvent gas generated during the heating process of the waste liquid; the collection tank 203 at one end of the purification box 202 can collect the recyclable organic solution separated by the gas-liquid separator 204, so as to realize resource recycling and reduce waste.

[0035] As an embodiment of this utility model, the input end of the gas-liquid separator 204 is connected to the upper side of the separation tank 206 via a pipe, and the output end of the gas-liquid separator 204 is connected to the top of the collection tank 203 via a pipe. The gas-liquid separator 204 is connected to the upper end of the separation tank 206 via a pipe, which can extract the gas generated in the separation tank 206 in a timely manner. The output end pipe is connected to the collection tank 203 to ensure that the separated recyclable materials are directly introduced into the collection tank 203, avoiding leakage and pollution or waste in the middle, and improving recycling efficiency and safety. As an embodiment of this utility model, further, several temperature sensors are vertically installed inside the heating jacket 207 along the axis of the separation tank 206. The monitoring ends of the temperature sensors are in contact with the outer wall of the separation tank 206. The several temperature sensors installed vertically inside the heating jacket 207 along the axis of the separation tank 206 can monitor the temperature at different heights of the separation tank 206 in real time, avoiding incomplete separation caused by excessively high or low local temperatures. The contact between the monitoring ends of the temperature sensors and the outer wall of the separation tank 206 ensures accurate temperature data, providing a basis for adjusting the power of the heating jacket 207 and achieving precise control of the waste liquid separation temperature.

[0036] Specifically, the working principle of the automatic waste liquid treatment and recovery device for this type of liquid chromatography-mass spectrometry instrument is as follows: In use, different types of waste liquid are first introduced into each waste liquid chamber 103 through the corresponding inlet pipe 105 on the cover 104 of the waste liquid tank 102. A filter screen 114 at the top of the waste liquid chamber 103 filters solid impurities, and a first liquid level sensor 111 inside monitors the waste liquid volume to prevent overflow. Then, the second solenoid valve 113 in the connecting pipe is opened, transferring the waste liquid in the waste liquid chamber 103 to the regulating tank 101. A pH sensor 117 on the inner wall of the regulating tank 101 monitors the pH value of the waste liquid in real time. A pump 108 draws the corresponding solution from the acid tank 106 or alkali tank 107 through a solenoid three-way valve 109 and injects it into the regulating tank 101. A drive motor 110 rotates the stirring rod 112 to fully mix the waste liquid with the acid and alkali solutions until the pH is adjusted to the target range. Finally, the third solenoid valve in the connecting pipe 115 is opened. 116. The pretreated waste liquid enters the separation tank 206 inside the separation box 201 through the connecting pipe 115. The heating jacket 207 starts heating, and the temperature sensor installed inside along the axis of the separation tank 206 monitors the temperature at various positions on the tank wall in real time to ensure uniform temperature and promote the vaporization of organic solvents in the waste liquid. The vaporized organic solvent vapor enters the gas-liquid separator 204 through the pipe. The separated organic solution is introduced into the collection tank 203 for recovery through the pipe. After the separation is completed, the first solenoid valve 210 in the drain pipe 211 is opened, and the unvaporized liquid enters the purification tank 202. After being evenly distributed by the flow equalization plate 208, it flows through the activated carbon filter layer 209 to adsorb impurities. Finally, the purified liquid is discharged through the drain pipe 205 or further recycled. The whole process realizes the automation of waste liquid classification and pretreatment, precise pH adjustment, solvent heating separation and recovery and liquid purification, improving treatment efficiency and resource utilization.

[0037] It should be noted that all standard parts used in this application can be purchased from the market, and can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. The control method is automatic control through a controller. The control circuit of the controller can be implemented by simple programming by those skilled in the art and is common knowledge in the field. Furthermore, since this application is mainly used to protect mechanical devices, this application will not explain the control method and circuit connection in detail.

Claims

1. An automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry instrument, characterized in that, The system includes a pretreatment mechanism (1) and a separation mechanism (2). The pretreatment mechanism (1) includes a regulating tank (101), with a waste liquid tank (102) installed at the upper end of the regulating tank (101). The waste liquid tank (102) has several waste liquid chambers (103) inside. An acid tank (106) and an alkali tank (107) are installed on one side of the regulating tank (101), and a connecting pipe (115) is installed at the bottom of the regulating tank (101). The separation mechanism (2) includes a separation tank (201), with the top of the separation tank (201) connected to the bottom of the regulating tank (101). A purification tank (202) is installed at the bottom of the separation tank (201), and the bottom of the separation tank (201) has a purification tank (202). A separation tank (206) is installed on one side of the separation tank (206), and a heating jacket (207) is fitted on the outside of the separation tank (206). The top of the separation tank (206) is connected to the bottom of the connecting pipe (115). A drain pipe (211) is provided at the bottom of the separation tank (206), and the bottom of the drain pipe (211) is connected to the top of the purification box (202). A first solenoid valve (210) is provided inside the drain pipe (211). A flow equalization plate (208) is installed at the upper end of the interior of the purification box (202). An activated carbon filter layer (209) is installed at the bottom of the flow equalization plate (208) inside the purification box (202). A drain pipe (205) is inserted at the bottom of the purification box (202).

2. The automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry instrument according to claim 1, characterized in that, Each waste liquid chamber (103) is equipped with a first liquid level sensor (111) on its inner side. Each waste liquid chamber (103) is equipped with a filter screen (114) at its upper end. Each waste liquid chamber (103) is equipped with a connecting pipe at its bottom end that communicates with the regulating box (101). Each connecting pipe is equipped with a second electromagnetic valve (113).

3. The automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry instrument according to claim 1, characterized in that, The waste liquid tank (102) is equipped with a cover (104) at the upper end, and each of the waste liquid chambers (103) on the cover (104) is equipped with an inlet pipe (105).

4. The automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry instrument according to claim 1, characterized in that, A stirring rod (112) is rotatably connected inside the regulating tank (101). A pH sensor (117) is installed on the inner side wall of the regulating tank (101). A drive motor (110) is fixedly installed at one end of the regulating tank (101). The drive motor (110) is connected to the stirring rod (112) through transmission. A third solenoid valve (116) is provided inside the connecting pipe (115).

5. The automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry instrument according to claim 1, characterized in that, A pump (108) is fixedly installed between the acid tank (106) and the alkali tank (107). The output end of the pump (108) is connected to the regulating box (101) through a pipe. The input end of the pump (108) is fitted with an electromagnetic three-way valve (109). The two ends of the electromagnetic three-way valve (109) are connected to the bottom of the acid tank (106) and the alkali tank (107) respectively through pipes.

6. The automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry instrument according to claim 1, characterized in that, A gas-liquid separator (204) is fixedly installed at one end of the separation box (201), and a collection tank (203) is fixedly installed at one end of the purification box (202).

7. The automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry instrument according to claim 6, characterized in that, The input end of the gas-liquid separator (204) is connected to the upper side of the separation tank (206) through a pipe, and the output end of the gas-liquid separator (204) is connected to the top of the collection tank (203) through a pipe.

8. The automatic waste liquid treatment and recovery device for a liquid chromatography-mass spectrometry instrument according to claim 1, characterized in that, Several temperature sensors are vertically installed inside the heating jacket (207) along the axis of the separation tank (206), and the monitoring end of the temperature sensor is in contact with the outer wall of the separation tank (206).

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