Light-proof sample rack for fluorescent PCR instrument

Abstract

The application discloses a light-proof sample rack for a fluorescent PCR instrument, which comprises a base plate connected with a box body through an angle adjusting structure, and the angle adjusting structure is used for driving and locking the inclination angle of the box body relative to the base plate. Through the angle adjusting structure, a user can adjust the sample rack to the most comfortable observation and operation angle, significantly reduces work fatigue, and improves operation accuracy. Through the design of multiple independent cavities and a placement plate, physical isolation and classified management of samples are allowed, cross contamination and sample confusion are effectively prevented, the placement plate is ensured to be smoothly pushed and pulled and accurately positioned through a guiding and locking structure, a built-in spring provides downward assistance, and the placement plate and a light shield assembly are locked in the box body. Through the setting of the light shield assembly, the side surface of the placement plate can be shaded when the placement plate is pulled out, and the shading effect is good.

Description

Technical Field

[0001] This application relates to the field of biological experimental equipment technology, specifically a light-proof sample rack for a fluorescence PCR instrument. Background Technology

[0002] Quantitative real-time PCR (polymerase chain reaction) is one of the core technologies in molecular biology. In this technique, the fluorescent probes and dyes used are highly sensitive to light; exposure to light can cause photobleaching, leading to quenching of the fluorescence signal and severely affecting the accuracy of the quantitative results. Therefore, samples require strict light protection during preparation and before testing.

[0003] Existing light-shielding sample racks mostly adopt an integrated structure, which has the following drawbacks: Most sample racks are placed horizontally, requiring researchers to bend over or stoop to clearly observe and retrieve samples, which can easily lead to visual fatigue and operational errors; they cannot be used for zoned management of samples, and when samples from different batches are placed on the same rack, confusion can easily occur; the integrated design cannot flexibly adjust the capacity as needed, and if a certain area is contaminated or damaged, it will affect the use of the entire sample rack; the simple light-shielding cover can only block light from the top and has poor sealing, so the side walls of the sample tubes may still be exposed to side light. Summary of the Invention

[0004] The technical problem to be solved by this application is to overcome the existing defects and provide a light-proof sample holder for a fluorescence PCR instrument, which can effectively solve the problems in the background art.

[0005] To achieve the above objectives, this application provides the following technical solution: a light-shielding sample holder for a fluorescence PCR instrument, comprising a substrate, wherein the substrate is connected to a housing via an angle adjustment structure, the angle adjustment structure being used to drive and lock the tilt angle of the housing relative to the substrate;

[0006] The box has at least two independent cavities. Each cavity is connected to a placement plate through a guide locking structure. The placement plate has a receiving groove for accommodating sample tubes.

[0007] A light shield assembly is provided at the upper end of the placement plate. The light shield assembly includes a cover body, a retaining plate, and a handle. The cover body is rotatably connected to the placement plate via a pivot. The retaining plate is located inside the cover body and corresponds to the receiving slot of the placement plate. The handle is located at the upper end of the cover body.

[0008] Furthermore, the angle adjustment structure includes a support plate, a locking plate, a sliding groove, and a locking bolt; there are two support plates, which are fixedly mounted on the base plate; the locking plates are fixed to both sides of the housing; the support plates are rotatably connected to the locking plates via connecting shafts; the sliding groove is formed on the support plate and is arc-shaped; the threaded end of the locking bolt passes through the sliding groove and engages with a threaded hole formed on the locking plate, and the locking plate and the support plate are relatively fixed by tightening the locking bolt.

[0009] Furthermore, the slide groove is concentrically arranged with the connecting shaft.

[0010] Furthermore, the guide locking structure includes a guide rod vertically disposed on the inner wall of the cavity and a slider disposed on the side of the placement plate, the slider being slidably engaged with the guide rod; a spring is sleeved on the guide rod, and the spring is located at the upper end of the slider.

[0011] Furthermore, the inner wall of the card plate is covered with a rubber pad.

[0012] Furthermore, both the box and the placement plate are made of opaque black ABS plastic.

[0013] Furthermore, the bottom of the substrate is provided with anti-slip pads.

[0014] Compared with existing technologies: This application, through its angle adjustment structure, allows users to adjust the sample rack to the most comfortable observation and operation angle, significantly reducing work fatigue and improving operational accuracy; the design of multiple independent cavities and placement plates allows for physical isolation and classification management of samples, effectively preventing cross-contamination and sample confusion; the guide locking structure ensures smooth pushing and pulling of the placement plate and precise positioning; its built-in spring provides downward assistance, locking the placement plate and light shield assembly into the box; the light shield assembly provides excellent light blocking effect by shielding the sides of the placement plate when it is pulled out. Attached Figure Description

[0015] Figure 1 This is a structural view of the present application;

[0016] Figure 2 A structural view of the light shield assembly;

[0017] Figure 3 This is a side view of this application;

[0018] Figure 4 First structural view of the guide locking structure and sunshade assembly;

[0019] Figure 5 A second structural view of the guide locking structure and the light shield assembly.

[0020] In the diagram: 1. Base plate; 2. Angle adjustment structure; 21. Support plate; 22. Locking plate; 23. Slide groove; 24. Locking bolt; 3. Box body; 5. Guide locking structure; 51. Guide rod; 52. Slider; 53. Spring; 6. Placement plate; 7. Receiving groove; 8. Light shield assembly; 81. Cover body; 82. Clamping plate; 83. Handle. Detailed Implementation

[0021] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of the embodiments. Based on the embodiments in this application (for ease of description and understanding, hereinafter referred to as...), Figure 1 (The above is described above). All other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of this application.

[0022] Please see Figure 1-5 This application provides a technical solution for a light-shielding sample holder for a fluorescence PCR instrument: a light-shielding sample holder for a fluorescence PCR instrument, mainly composed of a substrate 1, an angle adjustment structure 2, a box 3, a placement plate 6, and a light shield assembly 8.

[0023] The substrate 1 serves as the supporting base for the entire device, and its bottom is equipped with anti-slip pads. The anti-slip pads are usually made of rubber or silicone, which can effectively increase the friction with the table surface, prevent the sample rack from sliding or tipping over during operation, and ensure the safety and stability of the experimental process.

[0024] The angle adjustment structure 2 is the core of achieving ergonomic operation. It includes two support plates 21 fixed to the base plate 1, locking plates 22 fixed to both sides of the housing 3, a sliding groove 23 formed on the locking plate 22, and a locking bolt 24. The support plates 21 are rotatably connected to the locking plates 22 through a connecting shaft.

[0025] The slide groove 23 is arc-shaped, and its design is concentric with the connecting shaft, ensuring that the center of gravity of the box 3 remains stable and does not shift when adjusting the angle. When the angle needs to be adjusted, loosen the locking bolt 24, at which point the box 3 can rotate around the connecting shaft; after adjusting to the desired angle, tighten the locking bolt 24, and the head of the bolt will press firmly against the surface of the support plate 21. Through strong friction, the locking plate 22 and the support plate 21 are fixed together, thus achieving reliable angle locking. This structure is simple to adjust, securely locked, and can adapt to the needs of users of different heights and operating habits.

[0026] The interior of box 3 is divided into multiple independent cavities by partitions. In this embodiment, three cavities are preferred. Multiple independent cavities enable modular and partitioned management of samples. Samples from different batches or different experimental projects can be placed in different cavities, which are physically isolated, greatly avoiding the risk of confusion and cross-contamination, and improving the standardization and efficiency of laboratory management.

[0027] Each cavity is equipped with a set of guide locking structures 5. The structure includes a guide rod 51 vertically fixed to the inner wall of the cavity, a slider 52 fixed to the side of the placement plate 6, and a spring 53 sleeved on the guide rod 51 and located at the upper end of the slider 52; there are two guide locking structures 5 in each cavity.

[0028] The slider 52 and guide rod 51 work together to provide precise guidance for the pulling of the placement plate 6, ensuring smooth and stable movement. The spring 53 is located between the upper end of the slider 52 and the cavity, thus providing a downward force to lock the placement plate 6 and the light shield assembly 8 into the box.

[0029] The placement plate 6 is installed in the cavity via a guide locking structure 5. It has a receiving slot 7 for placing standard PCR tubes. Both the placement plate 6 and the housing 3 are made of opaque black ABS plastic. Black ABS plastic is used because the material itself is strong and corrosion-resistant, and black maximizes the absorption and scattering of light, preventing light from affecting the samples through the frame itself and providing basic light protection.

[0030] The light shield assembly 8 is rotatably connected to the placement plate 6 via a pivot. It includes a shield body 81, a retaining plate 82 fixed inside the shield body, and a handle 83 located at the top of the shield body. The inner wall of the retaining plate 82 is covered with a rubber pad. When the light shield is closed, the retaining plate 82 precisely engages with the side portion of the sample tube. The rubber pad on its inner side increases friction with the tube cap, ensuring a secure clamping and preventing the sample tube from loosening or popping out during movement; furthermore, the rubber pad provides flexible cushioning to prevent damage to the tube. When the placement plate 6 is removed, the shield body 81 protects the side portion of the removal area, ensuring the photosensitivity of the fluorescent sample is safe. The handle 83 is designed for easy opening and closing of the light shield.

[0031] In use: First, loosen the locking bolt 24, adjust the box 3 to a suitable angle, and then tighten it. Pull out the light shield assembly 8 and the placement plate 6 using the handle 83. Then, rotate the cover 81 using the handle 83 to open the light shield assembly 8, and place the sample tube into the receiving slot 7 of the placement plate 6. Close the light shield, and it will lock into the box 3 under the weight of the spring 53 and the placement plate 6. When sampling is required, open and pull out the light shield assembly 8 and the placement plate 6 again. Opening the light shield assembly 8 allows for easy access to the placement plate 6 or sample tubes. The entire design is interconnected, providing an optimal solution for safe, efficient, and comfortable fluorescent PCR experiments.

[0032] Although embodiments of this application have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of this application, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A light-proof sample holder for a fluorescence PCR instrument, characterized in that: Includes a substrate (1), which is connected to a housing (3) via an angle adjustment structure (2), the angle adjustment structure (2) being used to drive and lock the tilt angle of the housing (3) relative to the substrate (1); The box (3) has at least two independent cavities. Each cavity is connected to a placement plate (6) through a guide locking structure (5). The placement plate (6) has a receiving groove (7) for accommodating sample tubes. A light shield assembly (8) is provided on the upper end of the placement plate (6). The light shield assembly (8) includes a cover (81), a retaining plate (82), and a handle (83). The cover (81) is rotatably connected to the placement plate (6) through a rotating shaft. The retaining plate (82) is located inside the cover (81) and corresponds to the receiving groove (7) of the placement plate (6). The handle (83) is located on the upper end of the cover (81).

2. The light-proof sample holder for a fluorescence PCR instrument according to claim 1, characterized in that: The angle adjustment structure (2) includes a support plate (21), a locking plate (22), a slide groove (23), and a locking bolt (24). There are two support plates (21), which are fixedly set on the base plate (1). The locking plate (22) is fixed on both sides of the box body (3). The support plate (21) is rotatably connected to the locking plate (22) through a connecting shaft. The slide groove (23) is opened on the support plate (21) and is arc-shaped. The threaded end of the locking bolt (24) passes through the slide groove (23) and cooperates with the threaded hole opened on the locking plate (22). The locking plate (22) and the support plate (21) are relatively fixed by tightening the locking bolt (24).

3. The light-proof sample holder for a fluorescence PCR instrument according to claim 2, characterized in that: The slide (23) is concentrically arranged with the connecting shaft.

4. The light-proof sample holder for a fluorescence PCR instrument according to claim 1, characterized in that: The guide locking structure (5) includes a guide rod (51) vertically disposed on the inner wall of the cavity and a slider (52) disposed on the side of the placement plate (6). The slider (52) is slidably engaged with the guide rod (51). A spring (53) is sleeved on the guide rod (51) and the spring (53) is located at the upper end of the slider (52).

5. The light-proof sample holder for a fluorescence PCR instrument according to claim 1, characterized in that: The inner wall of the card plate (82) is covered with a rubber pad.

6. The light-proof sample holder for a fluorescence PCR instrument according to claim 1, characterized in that: Both the box body (3) and the placement plate (6) are made of opaque black ABS plastic.

7. The light-proof sample holder for a fluorescence PCR instrument according to claim 1, characterized in that: The bottom of the substrate (1) is provided with anti-slip pads.

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