A cryopreservation box tube-picking local low-temperature preservation device

Abstract

The utility model discloses a low temperature device is preserved to a kind of cryopreservation box pick tube local part, for carrying out pick tube to sample in cryopreservation box ontology, comprising: refrigeration unit;Pick tube unit, including the bottom plate for supporting the lower end of cryopreservation box ontology to pick tube process, the side plate for limiting the both sides of cryopreservation box ontology to pick tube process is equipped in bottom plate upper end close to both sides, the bottom plate with the side plate inside respectively be equipped with for preserving low temperature to the cryopreservation box ontology of pick tube process lower cryogenic channel, side cryogenic channel, the lower cryogenic channel is communicated with storage area inside for the transfer tube for cryogenic diffusion in storage area into lower cryogenic channel.Side cryogenic channel, lower cryogenic channel are communicated with storage area inside by transfer tube, so that the cold air in storage area is diffused into side cryogenic channel, lower cryogenic channel by transfer tube, avoid the temperature of cryopreservation box ontology to appear too big fluctuation.

Description

Technical Field

[0001] This utility model relates to the field of cryopreservation box tube picking technology, specifically a cryopreservation box tube picking device for local low temperature preservation. Background Technology

[0002] In the fields of biomedicine and life science research, cryopreservation boxes (such as cryopreservation tube racks and cryopreservation plates) are widely used for the long-term preservation of biological samples such as cells, tissues, and nucleic acids at low temperatures (usually -20℃ or -80℃). In daily experiments, it is often necessary to pick out specific cryopreservation tube samples from the cryopreservation boxes in the refrigerator. The common method for picking samples is to use a robotic arm to remove the cryopreservation box from the corresponding cryopreservation rack at -80°C and transfer it to -20°C for picking. This method causes the temperature of the cryopreservation box and other samples inside the box to rise sharply, resulting in large temperature fluctuations in the samples in a short period of time, which can cause irreversible damage to the activity of the samples. Therefore, this method is designed to improve this defect.

[0003] The above content is only used to help understand the technical solution of the present invention and does not represent an admission that the above content is the closest prior art. Utility Model Content

[0004] The purpose of this invention is to provide a local low-temperature preservation device for picking tubes from cryopreservation boxes, in order to solve the problem mentioned in the background art that when picking tubes from cryopreservation boxes in a refrigerator, the temperature of the samples fluctuates greatly, which may cause irreversible damage to the samples.

[0005] To achieve the above objectives, this utility model provides the following technical solution: A cryopreservation box tube picking and local low temperature preservation device for picking samples inside the cryopreservation box body, comprising: a refrigeration unit, including a storage area for refrigerating the cryopreservation box body, and a tube picking area provided on one side of the storage area for providing tube picking space for the cryopreservation box body tube picking operation, wherein a sealing door is provided between the storage area and the tube picking area. The tube-picking unit includes a base plate for supporting the lower end of the cryopreservation box body during the tube-picking process, and side plates located on the upper part of the base plate near both sides for limiting the sides of the cryopreservation box body during the tube-picking process. The base plate and the side plates are respectively provided with a lower low-temperature channel and a side low-temperature channel for keeping the cryopreservation box body at a low temperature during the tube-picking process. The lower low-temperature channel is connected to the storage area by a transfer tube for diffusing the low temperature in the storage area into the lower low-temperature channel.

[0006] Furthermore, the lower end of the lower cryogenic channel is provided with a second port that communicates with the interior of the transfer tube; The storage area is provided with a first port that communicates with the inside of the transfer tube, which is used to diffuse the cold air in the storage area into the lower low temperature channel in sequence through the first port, the transfer tube, and the second port.

[0007] Furthermore, the lower low-temperature channel is connected to the side low-temperature channel, and is used to diffuse the cold air in the lower low-temperature channel into the side low-temperature channel.

[0008] Furthermore, the bottom plate corresponding to the lower low-temperature channel and the cryopreservation box body, as well as the side plate between the low-temperature channel and the cryopreservation box body, are made of a heat-conducting material.

[0009] Furthermore, the pipe-picking unit also includes a drive mechanism, which includes: A support platform is installed at the bottom of the pipe-picking area; An electric cylinder is installed at the upper end of the support platform; A pusher plate, installed on the drive end of the electric cylinder, is used to push the cryopreservation box body on the upper part of the base plate into the storage area.

[0010] Furthermore, a gripper receiving groove is provided on one side of the side plate to reserve gripping space for the mechanical gripper to pick up and put down the cryopreservation box body at the upper end of the base plate.

[0011] Compared with the prior art, the beneficial effects of this utility model are: This invention involves a cryopreservation box being removed from the cryopreservation rack by a transfer robot within the storage area and then placed onto the bottom plate after passing through a sealed door. Because the side low-temperature channel and the lower low-temperature channel are connected to the interior of the storage area via transfer tubes, cold air from the storage area diffuses into the side low-temperature channel and the lower low-temperature channel through the transfer tubes. This ensures that the temperature of the cryopreservation box on the bottom plate is between that of the storage area and the tube-picking area, preventing excessive temperature fluctuations in the cryopreservation box and avoiding irreversible damage to the activity of the sample. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This diagram shows the relationship between the refrigeration unit and the lifting tube unit of this utility model. Figure 3 This is a schematic diagram of the pipe-picking unit structure of this utility model; Figure 4 This is a schematic diagram of the structure of the base plate and the internal structure of the storage area of ​​this utility model; Figure 5 This diagram shows the fit between the low-temperature channel and the gripper receiving groove of this utility model. Figure 6 This diagram shows the relationship between the lower low-temperature channel and the side low-temperature channel of this utility model.

[0013] Reference numerals: 100, cryogenic box body; 1, refrigeration unit; 11, storage area; 111, first opening; 12, tube picking area; 13, feeding tray; 14, sealing door; 2, tube picking unit; 21, bottom plate; 211, second opening; 212, lower low-temperature channel; 22, side plate; 221, gripper receiving groove; 222, side low-temperature channel; 23, drive mechanism; 231, support platform; 232, electric cylinder; 233, push plate; 24, transfer tube. Detailed Implementation

[0014] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0015] Please see Figure 1-6 This utility model provides a technical solution: A cryopreservation box sample picking and local temperature preservation device, used for picking samples from within the cryopreservation box body 100, comprising: The refrigeration unit 1 includes a storage area 11 for refrigerating the cryopreservation box body 100, and a tube-picking area 12 located on one side of the storage area 11 for providing tube-picking space for tube-picking work of the cryopreservation box body 100. A sealing door 14 is provided between the storage area 11 and the tube-picking area 12. The tube-picking unit 2 includes a base plate 21 for supporting the lower end of the cryopreservation box body 100 during the tube-picking process, and side plates 22 located on the upper end of the base plate 21 near both sides for limiting the sides of the cryopreservation box body 100 during the tube-picking process. The base plate 21 and the side plates 22 are respectively provided with a lower low-temperature channel 212 and a side low-temperature channel 222 for keeping the cryopreservation box body 100 at a low temperature during the tube-picking process. The lower low-temperature channel 212 is connected to the storage area 11 by a transfer tube 24 for diffusing the low temperature in the storage area 11 into the lower low-temperature channel 212.

[0016] It should be noted that when samples need to be picked from the cryopreservation box body 100, the corresponding cryopreservation box body 100 is taken out of the cryopreservation rack by the transfer robot in the storage area 11 and sent to the bottom plate 21 after passing through the sealing door 14. Since the side low temperature channel 222 and the lower low temperature channel 212 are connected to the inside of the storage area 11 through the transfer tube 24, the cold air in the storage area 11 diffuses into the side low temperature channel 222 and the lower low temperature channel 212 through the transfer tube 24, ensuring that the temperature of the cryopreservation box body 100 on the bottom plate 21 is between that in the storage area 11 and the picking area 12, avoiding excessive temperature fluctuations in the cryopreservation box body 100 that could irreversibly damage the activity of the samples.

[0017] As an improvement, the lower end of the lower cryogenic channel 212 is provided with a second port 211 that communicates with the interior of the transfer tube 24; The storage area 11 is provided with a first port 111 communicating with the inside of the transfer tube 24, which is used to diffuse the cold air in the storage area 11 into the lower low temperature channel 212 in sequence through the first port 111, the transfer tube 24, and the second port 211.

[0018] Furthermore, the lower low-temperature channel 212 is connected to the side low-temperature channel 222, and is used to diffuse the cold air in the lower low-temperature channel 212 into the side low-temperature channel 222.

[0019] Furthermore, the bottom plate 21 between the lower low-temperature channel 212 and the cryopreservation box body 100, as well as the side plate 22 between the low-temperature channel and the cryopreservation box body 100, are made of a heat-conducting material.

[0020] The tube-picking unit 2 further includes a drive mechanism 23, which includes: A support platform 231 is installed at the bottom of the pipe-picking area 12; An electric cylinder 232 is installed at the upper end of the support platform 231; Push plate 233, installed at the drive end of electric cylinder 232, is used to push the cryopreservation box body 100 on the upper end of base plate 21 into storage area 11.

[0021] In addition, a gripper receiving groove 221 is provided on one side of the side plate 22 to reserve gripping space for mechanical grippers to pick up and put down the cryopreservation box body 100 at the upper end of the base plate 21.

[0022] It should be added that the front end of the tube picking area 12 is provided with a feeding tray 13 for transporting the cryopreservation box body 100 into the tube picking area 12. The tube picking area 12 is provided with a mechanical gripper for transporting the cryopreservation box body 100 from the feeding tray 13 to the bottom plate 21. The storage area 11 is provided with a transfer robot for sending the cryopreservation box body 100 that needs to be picked into the storage area 11 to the bottom plate 21. The transfer robot and the mechanical gripper are not shown in the figure. The temperature in storage area 11 is -80℃, and the temperature in tube picking area 12 is -20℃.

[0023] Working principle: In the specific implementation of this utility model, when it is necessary to pick the sample in the cryopreservation box body 100, the corresponding cryopreservation box body 100 is taken out from the cryopreservation rack by the transfer robot in the storage area 11 and sent to the bottom plate 21 after passing through the sealing door 14. Since the side low temperature channel 222 and the lower low temperature channel 212 are connected to the inside of the storage area 11 through the transfer tube 24, the cold air in the storage area 11 diffuses into the side low temperature channel 222 and the lower low temperature channel 212 through the transfer tube 24, ensuring that the temperature of the cryopreservation box body 100 located on the bottom plate 21 is between that in the storage area 11 and the picking area 12. This prevents the temperature of the cryopreservation box body 100 from rising rapidly when it is transferred out of the storage area 11 for picking, thus preventing irreversible damage to the active sample. During the process of the cryopreservation box body 100 entering the tube picking area 12 from the storage area 11 or entering the storage area 11 from the tube picking area 12, the sealing door 14 automatically opens and closes under the action of signal control. After the tube picking is completed, the electric cylinder 232 is activated. The electric cylinder 232 drives the pusher plate 233 to push the cryopreservation box body 100 from the tube picking area 12 into the storage area 11. Subsequently, the transfer robot in the storage area 11 picks up the cryopreservation box body 100 and places it on the cryopreservation rack for storage, thus completing the tube picking and resetting work of the cryopreservation box body 100.

[0024] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0025] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A cryopreservation box sample picking and local temperature preservation device, used for picking samples from the cryopreservation box body (100), characterized in that, include: The refrigeration unit (1) includes a storage area (11) for refrigerating the cryopreservation box body (100), and a tube-picking area (12) located on one side of the storage area (11) for providing tube-picking space for the tube-picking work of the cryopreservation box body (100). A sealing door (14) is provided between the storage area (11) and the tube-picking area (12). The tube-picking unit (2) includes a base plate (21) for supporting the lower end of the cryopreservation box body (100) during the tube-picking process, and a side plate (22) located on the upper end of the base plate (21) near both sides for limiting the sides of the cryopreservation box body (100) during the tube-picking process. The base plate (21) and the side plate (22) are respectively provided with a lower low temperature channel (212) and a side low temperature channel (222) for keeping the cryopreservation box body (100) at a low temperature during the tube-picking process. The lower low temperature channel (212) is connected to the storage area (11) by a transfer tube (24) for diffusing the low temperature in the storage area (11) to the lower low temperature channel (212).

2. The cryopreservation box tube-lifting local low-temperature preservation device according to claim 1, characterized in that: The lower end of the lower low-temperature channel (212) is provided with a second port (211) that communicates with the interior of the transfer tube (24); The storage area (11) is provided with a first port (111) communicating with the inside of the transfer tube (24) on one side, which is used to diffuse the cold air in the storage area (11) into the lower low temperature channel (212) in sequence through the first port (111), the transfer tube (24), and the second port (211).

3. The cryopreservation box tube-lifting local low-temperature preservation device according to claim 1, characterized in that: The lower low-temperature channel (212) is connected to the side low-temperature channel (222) and is used to diffuse the cold air in the lower low-temperature channel (212) into the side low-temperature channel (222).

4. The cryopreservation box tube-lifting local low-temperature preservation device according to claim 3, characterized in that: The bottom plate (21) between the lower low-temperature channel (212) and the cryopreservation box body (100) and the side plate (22) between the low-temperature channel and the cryopreservation box body (100) are made of a heat-conducting material.

5. The cryopreservation box tube-lifting local low-temperature preservation device according to claim 1, characterized in that: The tube-picking unit (2) further includes a drive mechanism (23), which includes: A support platform (231) is installed at the bottom of the pipe-picking area (12); An electric cylinder (232) is installed at the upper end of the support platform (231); A push plate (233) is installed at the drive end of the electric cylinder (232) to push the cryopreservation box body (100) at the upper end of the base plate (21) into the storage area (11).

6. The cryopreservation box tube-lifting local low-temperature preservation device according to claim 1, characterized in that: The side plate (22) is provided with a claw receiving groove (221) on one side, which is used to reserve a clamping space for the mechanical claw to pick up and put the cryopreservation box body (100) at the upper end of the bottom plate (21).

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