A fluorescent immunoassay quantitative analyzer

Abstract

The utility model provides a kind of fluorescent immunoassay quantitative analyzer, belong to fluorescent immunoassay technical field, including host computer, be equipped with interactive module on the host computer, the inside of host computer is equipped with motion module, detection module is equipped on the motion module, the inside of host computer is also equipped with mainboard, the inside of host computer is also equipped with incubation system, and the mainboard is electrically connected with interactive module.The utility model solves the current fluorescent immunoassay technique mostly single reagent card, one cycle can only detect one kind of substance.But it cannot detect, for example, antigen and antibody, blood sugar, blood fat etc simultaneously, while desktop instrument on market mostly is plug and play, determine reagent card position positioning detection, and the instrument with high degree of automation is mostly large instrument, and small desktop instrument with multiple shaft linkage is very few.

Description

Technical Field

[0001] This invention belongs to the field of fluorescence immunoassay technology, specifically a fluorescence immunoassay quantitative analyzer. Background Technology

[0002] A fluorescence immunoassay analyzer is an instrument capable of measuring and quantifying trace amounts of substances. It converts the structure and properties of substances into visible, measurable spectral signals. It features high detection sensitivity, speed, accuracy, and ease of operation, and is unaffected by the properties of the substance being analyzed, making it one of the most important analytical and detection technologies today.

[0003] Existing fluorescence immunoassay techniques mostly use single reagent cards, detecting only one substance per cycle. They cannot simultaneously detect substances such as antigens and antibodies, blood glucose, and blood lipids. Furthermore, there is a lack of small, benchtop instruments capable of simultaneously detecting multiple types of reagent cards. Most benchtop instruments on the market are plug-and-play, requiring precise reagent card positioning, while highly automated instruments are mostly large-scale. Small, multi-axis benchtop instruments are rare. This invention addresses these issues by providing an automated detection instrument that can complete multiple sample tests in a single run, increasing detection diversity while reducing costs and improving efficiency. Utility Model Content

[0004] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be construed as limiting the scope of the present invention.

[0005] Given the following technical problems in the existing technology: how to design an automated detection instrument that can complete multiple sample tests in a single run, thereby improving detection diversity while reducing costs and increasing efficiency.

[0006] To solve the above-mentioned technical problems, this utility model provides the following technical solution: a fluorescence immunoassay analyzer, including a host, an interactive module on the host, a motion module inside the host, a detection module on the motion module, a motherboard inside the host, and an incubation system inside the host, the motherboard being electrically connected to the interactive module.

[0007] As a preferred technical solution for a fluorescence immunoassay analyzer, the main unit includes an upper shell and a lower shell, which are fastened together by pins. The interaction module includes a display screen embedded in the surface of the upper shell, and the display screen is provided with an interactive interface.

[0008] As a preferred technical solution for a fluorescence immunoassay analyzer, the motion module includes a base plate installed inside the host and located on the upper side of the motherboard. The left and right sides of the front end of the base plate are integrally formed with receiving plates. A motion plate is installed on the base plate. Guide rails are fixed on both sides of the base plate. A slider slides on the guide rails. The slider is fixed to the motion plate by bolts. A support strip is fixed to the front side of the upper surface of the motion plate by bolts.

[0009] As a preferred technical solution for a fluorescence immunoassay analyzer, the motion module further includes a first bracket and a second bracket that are respectively mounted on the motion plate and the base plate by bolts. A first motor and a second motor are respectively mounted on the first bracket and the second bracket, and the first motor and the second motor are perpendicular to each other on the horizontal plane.

[0010] As a preferred technical solution for a fluorescence immunoassay analyzer, the ends of the first motor and the second motor are respectively equipped with a first synchronous pulley group and a second synchronous pulley group. Two transmission brackets are respectively installed on the front side of the first synchronous pulley group and the second synchronous pulley group. The two transmission brackets of each group are connected by a belt. The second synchronous pulley group and its belt are located below the motion plate. A clamping plate is installed on the lower side of the middle part of the motion plate. The belt of the second synchronous pulley group is clamped between the clamping plate and the motion plate.

[0011] As a preferred technical solution for a fluorescence immunoassay analyzer, the detection module includes a fixing block slidably mounted on a support bar, one end of the fixing block being clamped onto the belt of the first synchronous pulley group, and the other end of the fixing block being equipped with a detection mechanism.

[0012] As a preferred technical solution for a fluorescence immunoassay analyzer, the incubation system includes an upper plate and a lower plate connected to each other by bolts. Multiple reagent card incubation chambers are reserved between the upper plate and the lower plate. The upper plate has corresponding openings on the upper side of the reagent card incubation chambers. Ear plates are fixed on both sides of the lower plate. The ear plates are fixed to the receiving plate by bolts. An air duct is installed on the lower side of the lower plate by bolts. A temperature monitoring PCB board is installed on the rear side of the upper and lower plates. A thermal balance mechanism is installed at the bottom of the lower plate. The detection mechanism is located on the upper side of the opening.

[0013] As a preferred technical solution for a fluorescence immunoassay analyzer, the motherboard is embedded with a processor module, a power module, a device driver module, a signal conditioning module, and a printer module. The power module supplies power to each module. The device driver module acquires fluorescence signals and transmits them to the signal conditioning module. The signal conditioning module processes the signals and transmits them to the processor module. The processor module is electrically connected to the display screen and controls the display screen and printer module to output results.

[0014] As a preferred technical solution for a fluorescence immunoassay analyzer, the host also includes a power button, a power interface, a data interface, a network port, and a USB interface, all of which are located on the outer side of the host.

[0015] The beneficial effects of this utility model are:

[0016] 1. This utility model, through the setting of the incubation system, supports the mixed use of multiple reagent cards, which is the physical basis for realizing single-run, multi-index detection, and directly brings about an improvement in detection efficiency and diversity.

[0017] 2. This utility model, through the setup of a motion module and a detection module, uses a precision motor and transmission mechanism to drive the detection module to move accurately in a two-dimensional plane, replacing manual positioning and achieving fully automatic scanning. All these mechanisms are highly integrated into the main unit, achieving a unity of automation and miniaturization.

[0018] 3. This utility model reduces the complexity and cost of electronic systems through the configuration of the motherboard, the highly integrated processor, device driver module and signal processing module. Attached Figure Description

[0019] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Among them:

[0020] Figure 1 This is a schematic diagram of the external front structure of an embodiment of the present utility model;

[0021] Figure 2 This is a schematic diagram of the external rear structure of an embodiment of the present utility model;

[0022] Figure 3 This is a schematic diagram of the motion module, motherboard, detection module, and incubation system structure according to an embodiment of the present utility model;

[0023] Figure 4 This is a schematic diagram of the incubation system structure according to an embodiment of the present invention;

[0024] Figure 5 This is a schematic diagram of the motion module structure according to an embodiment of the present utility model;

[0025] Figure 6 This is a schematic diagram of the external front structure of an embodiment of the present utility model;

[0026] Figure 7This is a schematic diagram of the motion module, motherboard, detection module, and incubation system structure according to an embodiment of the present utility model;

[0027] Figure 8 This is a schematic diagram of the incubation system structure according to an embodiment of the present invention;

[0028] Figure 9 This is a schematic diagram of the module connection structure of an embodiment of the present utility model;

[0029] Reference numerals: 100, Main unit; 101, Upper shell; 102, Lower shell; 103, Power button; 104, Power interface; 105, Data interface; 106, Ethernet port; 107, USB interface; 200, Interaction module; 201, Display screen; 300, Motion module; 301, Base plate; 302, Motion plate; 303, Guide rail; 304, Slider; 305, Support bar; 306, First bracket; 307, Second bracket; 308, First motor; 309, Second motor; 310, First synchronous belt pulley set; 31 1. Second synchronous pulley set; 312. Transmission bracket; 313. Belt; 314. Clamping plate; 400. Detection module; 401. Fixing block; 402. Detection mechanism; 500. Main board; 501. Processor module; 502. Power supply module; 503. Equipment drive module; 504. Signal conditioning module; 505. Printer module; 600. Incubation system; 601. Upper board; 602. Lower board; 603. Reagent card incubation chamber; 604. Opening; 605. Ear plate; 606. Air duct; 607. Temperature monitoring PCB board. Detailed Implementation

[0030] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings.

[0031] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Those skilled in the art can make similar extensions without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0032] Secondly, the term "an embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that excludes other embodiments.

[0033] Secondly, this utility model is described in detail with reference to the schematic diagrams. When describing the embodiments of this utility model, for ease of explanation, the cross-sectional views illustrating the device structure may be partially enlarged, not adhering to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of this utility model. In addition, actual manufacturing should include the three-dimensional spatial dimensions of length, width, and depth.

[0034] Example 1

[0035] Reference Figures 1-9 This embodiment provides a fluorescence immunoassay analyzer, including a host 100, an interaction module 200 on the host 100, a motion module 300 inside the host 100, a detection module 400 on the motion module 300, a motherboard 500 inside the host 100, and an incubation system 600 inside the host 100. A sample code scanning mechanism and an ID card reading mechanism are also integrated on both sides of the host (100). The motherboard (500) is electrically connected to the interaction module (200), the sample code scanning mechanism, and the ID card reading mechanism.

[0036] The main unit 100, as the core shell of the device, not only provides structural support and protection for internal components, but also ensures the stability and portability of the device through its design. The main unit 100 is equipped with an interactive module 200, which allows users to intuitively operate and monitor the testing process, enhancing the user experience. The sample code scanning mechanism and ID card reading mechanism integrated on both sides of the main unit 100 enable users to conveniently complete the input and binding of sample information and patient identity at the same workstation, achieving closed-loop management of the testing process and effectively avoiding sample confusion and information errors. The main unit 100 internally houses a motion module 300, which is responsible for precise control. The movement of the detection components enables efficient multi-channel detection; the motion module 300 is equipped with a detection module 400, which is specifically designed to collect fluorescence signals to ensure the accuracy and sensitivity of the detection; the host 100 also houses a motherboard 500, which serves as the control center of the device, coordinating the operation of each module and data processing; the host 100 also houses an incubation system 600, which provides a constant temperature environment for the reagent cards to ensure the stable progress of the biochemical reaction; the motherboard 500 is electrically connected to the interaction module 200, the sample code scanning mechanism, and the ID card reading mechanism to achieve real-time data transmission and response to user commands.

[0037] Specifically, the sample code scanning mechanism is fixed to the left side of the main unit 100 via a bracket, with its scanning window facing outwards for easy scanning by the user; the ID card reading mechanism is fixed to the right side of the main unit 100 via a bracket, with its card reader slot tightly fitted to the main unit's casing. The sample code scanning mechanism uses an embedded one-dimensional / two-dimensional barcode scanning engine for quickly reading barcodes on sample tubes; the ID card reading mechanism is a dedicated radio frequency identification (RFID) reader compliant with the Ministry of Public Security standards, used to read and verify encrypted information within resident ID cards. Both are connected to the processor module 501 on the motherboard 500 via internal cables. The scanned or read data is processed uniformly by the processor module 501 and associated with and stored with the corresponding test results.

[0038] Specifically, the host 100 includes an upper shell 101 and a lower shell 102, which are fastened together by pins. The interaction module 200 includes a display screen 201 embedded on the surface of the upper shell 101, and the display screen 201 is provided with an interactive interface.

[0039] The upper shell 101 and the lower shell 102 are fastened together by pins, which not only facilitates assembly and maintenance, but also enhances the sealing and durability of the equipment; users can set parameters, view real-time data and test results through the interactive interface of the display screen 201, simplifying the operation process.

[0040] Specifically, the motion module 300 includes a base plate 301 installed inside the host 100 on the upper side of the motherboard 500. The left and right sides of the front end of the base plate 301 are integrally formed with receiving plates. A motion plate 302 is installed on the base plate 301. Guide rails 303 are fixed on both sides of the base plate 301. A slider 304 slides on the guide rails 303. The slider 304 is fixed to the motion plate 302 by bolts. A support strip 305 is fixed to the front side of the upper surface of the motion plate 302 by bolts.

[0041] The base plate 301 serves as the basic platform for the moving parts, ensuring the stability of the overall structure. The integrated support plates on the left and right sides of the front end of the base plate 301 are used to fix other components. The motion plate 302 can move on the horizontal plane to achieve precise positioning of the detection module 400. Guide rails 303 are fixed on both sides of the base plate 301, and sliders 304 slide on the guide rails 303. The sliders 304 are fixed to the motion plate 302 by bolts. This mechanism reduces friction, improves motion accuracy and lifespan, and at the same time, the guide rails 303 can limit the sliding path of the sliders 304. The support bar 305 is used to support the detection module 400 and ensure its stability during movement.

[0042] Specifically, the motion module 300 also includes a first bracket 306 and a second bracket 307 that are respectively bolted to the motion plate 302 and the base plate 301. A first motor 308 and a second motor 309 are respectively mounted on the first bracket 306 and the second bracket 307. The first motor 308 and the second motor 309 are perpendicular to each other on the horizontal plane.

[0043] The motion module 300 also includes a first bracket 306 and a second bracket 307 that are bolted to the motion plate 302 and the base plate 301 respectively. A first motor 308 and a second motor 309 are respectively mounted on the first bracket 306 and the second bracket 307. The first motor 308 and the second motor 309 are perpendicular to each other on the horizontal plane. This arrangement enables the detection module 400 to be independently controlled in the X and Y directions, thereby covering multiple detection points.

[0044] Specifically, the ends of the first motor 308 and the second motor 309 are respectively equipped with a first synchronous pulley group 310 and a second synchronous pulley group 311. Two transmission brackets 312 are respectively installed on the front side of the first synchronous pulley group 310 and the second synchronous pulley group 311. The two transmission brackets 312 of each group are connected by a belt 313. The second synchronous pulley group 311 and its belt 313 are located below the motion plate 302. A clamping plate 314 is installed on the lower side of the middle part of the motion plate 302. The belt 313 of the second synchronous pulley group 311 is clamped between the clamping plate 314 and the motion plate 302.

[0045] The ends of the first motor 308 and the second motor 309 are respectively equipped with a first synchronous pulley set 310 and a second synchronous pulley set 311. The first synchronous pulley set 310 and the second synchronous pulley set 311 can convert the rotational motion of the first motor 308 and the second motor 309 into linear motion, thereby improving transmission efficiency. Two transmission brackets 312 are respectively installed on the front side of the first synchronous pulley set 310 and the second synchronous pulley set 311. The two transmission brackets 312 in each set are connected by a belt 313. The belt 313 transmission method reduces noise and vibration, ensuring... To ensure smooth movement and provide power and mounting position for the movement of the detection module 400; the second synchronous pulley set 311 and its belt 313 are located below the motion plate 302. A clamping plate 314 is installed on the lower side of the middle part of the motion plate 302. The belt 313 of the second synchronous pulley set 311 is clamped between the clamping plate 314 and the motion plate 302. This clamping structure enables the motion plate 302 to be firmly clamped on the belt 313 of the second synchronous pulley set 311, thereby enabling the second synchronous pulley set 311 to drive the motion plate 302 to move horizontally in the Y direction.

[0046] Specifically, the detection module 400 includes a fixing block 401 that is slidably mounted on the support bar 305. One end of the fixing block 401 is clamped to the belt 313 of the first synchronous pulley set 310, and the other end of the fixing block 401 is equipped with a detection mechanism 402.

[0047] One end of the fixed block 401 is clamped onto the belt 313 of the first synchronous pulley group 310, and the fixed block 401 is linearly moved by the belt 313. The other end of the fixed block 401 is equipped with a detection mechanism 402, which includes an optical sensor and a signal acquisition unit for exciting fluorescence and receiving signals, thereby realizing quantitative analysis of the reagent card. A sensing head is fixed on the detection mechanism 402, and precise X-direction scanning position movement control is achieved through an optical coupler.

[0048] Specifically, the incubation system 600 includes an upper plate 601 and a lower plate 602 connected to each other by bolts. Multiple reagent card incubation chambers 603 are reserved between the upper plate 601 and the lower plate 602. The upper plate 601 has corresponding openings 604 on the upper side of the reagent card incubation chambers 603. Ear plates 605 are fixed on both sides of the lower plate 602. The ear plates 605 are fixed to the receiving plate by bolts. An air duct 606 is installed on the lower side of the lower plate 602 by bolts. A temperature monitoring PCB board 607 is installed on the rear side of the upper plate 601 and the lower plate 602. A thermal balance mechanism is installed at the bottom of the lower plate 602. The detection mechanism 402 is located on the upper side of the opening 604.

[0049] Each reagent card incubation cavity 603 can independently accommodate a reagent card, supporting multi-channel parallel detection. Each reagent card incubation cavity 603 has an internal elastic element that compresses from bottom to top. When a reagent card is inserted, the elastic element clamps the card against the upper wall of the reagent card incubation cavity 603, preventing displacement. The upper plate 601 has a corresponding opening 604 on the upper side of the reagent card incubation cavity 603, facilitating signal acquisition by the detection mechanism 402. Ear plates 605 fixed on both sides of the lower plate 602 ensure the incubation system 600 is securely installed inside the main unit 100. The air duct 606 has an air inlet on one side and an air outlet on the other side, allowing any... A fan is installed at one of the air vents to evenly distribute heat, ensure air circulation, and maintain a constant temperature environment within the reagent card incubation chamber 603. A temperature monitoring PCB board 607 is installed on the rear side of the upper plate 601 and the lower plate 602. This board monitors temperature changes in real time and adjusts them through feedback to ensure stable incubation conditions. A thermal balance mechanism is installed at the bottom of the lower plate 602. This mechanism includes heating elements and heat dissipation devices, which can quickly heat up and maintain the temperature, ensuring that the reagent card incubation chamber 603 can always be kept at a constant temperature, thus improving detection efficiency. The detection mechanism 402 is located on the upper side of the opening 604, ensuring that it is accurately aligned with each incubation chamber for detection under the drive of the motion module 300.

[0050] In this embodiment, the reagent card incubation chambers 603 are configured in a high-throughput homogeneous layout, with six chambers of uniform size, specifically designed to accommodate standard-sized single-ply reagent cards. This design allows the instrument to simultaneously insert six single-ply cards and perform parallel incubation and detection on up to six reagent cards. Its core advantage lies in achieving extremely high detection efficiency, making it particularly suitable for large-scale screening or repetitive experiments for a single indicator. All six incubation chambers are thermodynamically in the same environment, precisely controlled by the same temperature monitoring PCB board 607 and thermal balance mechanism, ensuring high temperature uniformity at each reaction site, thereby guaranteeing the comparability and accuracy of batch detection results. The upper plate 601, located on the upper side of each reagent card incubation chamber 603, has a corresponding opening 604, allowing the detection mechanism 402 to sequentially or programmatically acquire fluorescence signals from the reagent cards within each chamber. Ear plates 605 are fixed on both sides of the lower plate 602. The ear plates 605 are fixed to the receiving plate at the front end of the base plate 301 of the motion module 300 by bolts, so as to realize the stable installation of the incubation system 600 inside the host 100.

[0051] Specifically, the motherboard 500 is equipped with a processor module 501, a power module 502, a device driver module 503, a signal conditioning module 504, and a printer module 505. The power module 502 supplies power to each module. The device driver module 503 acquires the fluorescent signal and transmits it to the signal conditioning module 504. The signal conditioning module 504 processes the signal and transmits it to the processor module 501. The processor module 501 is electrically connected to the display screen 201 and controls the display screen 201 and the printer module 505 to output the results.

[0052] The power supply module 502 embedded on the motherboard 500 supplies power to each module to ensure stable operation of the device; the device driver module 503 acquires the fluorescent signal and transmits it to the signal conditioning module 504, which amplifies and filters the signal to improve the signal-to-noise ratio; the processor module 501 is electrically connected to the display screen 201 and controls the display screen 201 and the printer module 505 to output results, realizing real-time display and printing of data, which is convenient for users to record and analyze. The processor module 501 is based on the STM32H743 series chip with ARM Cortex-M7 core. It communicates with the device driver module 503 and the signal conditioning module 504 through a parallel bus or a high-speed serial bus (such as SPI, I2C), connects to the display screen 201 of the interaction module 200 through a display controller interface (such as an RGB interface) to drive the graphical interface, and controls the printer module 505 through an asynchronous serial interface (UART) or parallel port. The processor module 501 is typically equipped with SDRAM (such as IS42S16400J) and FLASH (such as W25Q64JV) memory chips, which are used for data caching and storing firmware programs, calibration parameters and test results during program execution, respectively. The device driver module 503 can integrate two stepper motor driver chips, such as DRV8825. This chip receives pulse and direction signals from the processor module 501 through the STEP / DIR interface and outputs sufficient current and voltage to drive the motor to step precisely. Meanwhile, this module directly or indirectly acquires a weak fluorescent analog voltage signal from the preamplifier circuit of the photodetector (such as a photomultiplier tube or avalanche photodiode) in the detection mechanism 402 via a high-precision analog-to-digital converter (ADC), such as ADS1256. The signal conditioning module 504 uses AD8221 to pre-amplify the signal. Its subsequent stage can be connected to a programmable gain amplifier (PGA) composed of an operational amplifier (such as OPA2188) and an RC network, and a low-pass filter (such as an active filter based on LTC1562) to further adjust the signal amplitude and filter out high-frequency noise. The conditioned analog signal is sent to the high-precision ADC in the device driver module 503 for digitization. The printer module 505 integrates the driving circuit of the thermal printhead. This module receives the printing data and instructions sent by the processor module 501, and drives the thermal printhead through a dedicated print control chip TCD1304AP to accurately print the test report, QR code and waveform on the thermal paper.

[0053] Specifically, the host 100 also includes a power button 103, a power interface 104, a data interface 105, a network port 106, and a USB interface 107. The power button 103, power interface 104, data interface 105, network port 106, and USB interface 107 are all located on the outer side of the host 100.

[0054] The power button 103 is used to start and stop the device. The power interface 104 is connected to an external power source. The data interface 105, network port 106, and USB interface 107 are all located on the outer side of the host 100, supporting data transmission, network connection, and external device expansion, thereby enhancing the device's versatility and interconnectivity.

[0055] Example 2

[0056] Reference Figures 1-9 The incubation system 600 includes an upper plate 601 and a lower plate 602 connected to each other by bolts, with a reagent card incubation cavity 603 reserved between the upper plate 601 and the lower plate 602. In this embodiment, the reagent card incubation cavity 603 adopts a multi-functional composite layout. Its cavity structure and number are specially designed to simultaneously accommodate and lock one single-card, one double-card, and one six-card, greatly improving the instrument's detection flexibility and throughput, allowing multiple different analytes to be detected simultaneously in a single run. For example, in one test, the operator can use the single-card to detect item A, the double-card to simultaneously detect items B and C, and the six-card to simultaneously detect items D to I, thereby achieving joint analysis of up to nine different indicators. This mode is very suitable for scenarios requiring multi-indicator joint diagnosis. The upper plate 601 is precisely provided with openings 604 above each corresponding slot for single-card, double-card, and six-card, ensuring that the detection mechanism 402 can access each reaction orifice without obstruction. Ear plates 605 are fixed to both sides of the lower plate 602 and secured to the receiving plate with bolts. Although reagent cards of different numbers are inserted into the reagent card incubation chamber 603, the system can still effectively maintain a stable temperature field throughout the incubation area through the optimized air duct design 606 and the precise control of the thermal balance mechanism, supplemented by real-time feedback from the temperature monitoring PCB board 607. This ensures that various biochemical reactions on different reagent cards can proceed smoothly under their respective optimal temperature conditions, guaranteeing the synchronous and reliable results of multiple tests.

[0057] Workflow: After the instrument is powered on and completes its self-test, the user first enters and binds information. This is done by scanning the barcode on the sample tube using the sample code scanning mechanism on the left side of the main unit 100, and then reading the patient's ID card information using the ID card reader on the right side. The processor module 501 automatically binds the sample information with the patient's identity information and confirms this on the display screen 201. Subsequently, the user inserts reagent cards into the reagent card incubation chamber 603 of the incubation system 600 according to their testing needs. If a high-throughput homogenized layout incubation system 600 is used, six identical single-card packs can be inserted simultaneously for batch testing of a single indicator. If a multi-functional composite layout incubation system 600 is used, one single-card pack, one double-card pack, and one six-card pack can be inserted together to achieve joint analysis of up to nine different indicators. Once the reagent card is loaded, the incubation system 600 starts immediately. Its bottom thermal balance mechanism starts working under the real-time feedback of the temperature monitoring PCB board 607. Through the precise air duct design 606, all incubation chambers quickly reach and stabilize at the preset reaction temperature, providing a constant and ideal environment for the immunochemical reaction.

[0058] Once the incubation process is complete, the system automatically enters the detection phase. At this time, the motion module 300 begins to work collaboratively: the second motor 309 first drives the second synchronous pulley group 311 to rotate, which, through the belt 313 clamped between the clamping plate 314 and the motion plate 302, moves the entire motion plate 302 and its front-end detection module 400 along the Y-axis, positioning it above the row where the target reagent card is located; subsequently, the first motor 308 drives the first synchronous pulley group 310 to rotate, which, through the belt 313, moves the fixing block 401 and the detection mechanism 402 along the X-axis, allowing its optical system to be precisely positioned directly above the specific reaction hole with the help of the sensor head and the optocoupler. After positioning, the detection mechanism 402 then emits excitation light into the reaction area of ​​the reagent card through the opening 604 of the incubation upper plate 601, and simultaneously collects the generated fluorescence signal.

[0059] After the fluorescence signal is acquired by the device driver module 503, it is transmitted to the signal conditioning module 504 for amplification, filtering, and other processing to improve the signal-to-noise ratio, and then converted into a digital signal and sent to the processor module 501. The processor module 501 performs quantitative analysis on the signal based on pre-stored calibration parameters and standard curves to calculate the precise concentration of the analyte. Finally, the detection results are presented to the user in real time on the display screen 201, and a paper report can be printed by the printer module 505, or the data can be exported via the data interface 105, network port 106, and USB interface 107, thus completing a fully automated, multi-channel fluorescence immunoassay quantitative analysis process from incubation to result output.

[0060] It should be understood that numerous specific implementation decisions can be made during the development of any practical implementation, such as in any engineering or design project. Such development efforts may be complex and time-consuming, but for those skilled in the art who benefit from this disclosure, the development effort will be a routine work of design, manufacturing, and production without requiring much experimentation.

[0061] It should be noted that the above embodiments are only used to illustrate the technical solution of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solution of this utility model without departing from the spirit and scope of the technical solution of this utility model, and all such modifications or substitutions should be covered within the scope of the claims of this utility model.

Claims

1. A fluorescence immunoassay analyzer, characterized in that: The system includes a host (100), an interaction module (200) on the host (100), a motion module (300) inside the host (100), a detection module (400) on the motion module (300), a motherboard (500) inside the host (100), and an incubation system (600) inside the host (100). The motherboard (500) is electrically connected to the interaction module (200).

2. The fluorescence immunoassay analyzer according to claim 1, characterized in that: The host (100) includes an upper shell (101) and a lower shell (102), which are fastened together by a pin. The interaction module (200) includes a display screen (201) embedded on the surface of the upper shell (101), and the display screen (201) is provided with an interactive interface.

3. The fluorescence immunoassay analyzer according to claim 2, characterized in that: The motion module (300) includes a base plate (301) installed inside the host (100) on the upper side of the motherboard (500). The left and right sides of the front end of the base plate (301) are integrally formed with receiving plates. A motion plate (302) is installed on the base plate (301). Guide rails (303) are fixed on both sides of the base plate (301). A slider (304) slides on the guide rails (303). The slider (304) is fixed to the motion plate (302) by bolts. A support strip (305) is fixed to the front side of the upper surface of the motion plate (302) by bolts.

4. The fluorescence immunoassay analyzer according to claim 3, characterized in that: The motion module (300) also includes a first bracket (306) and a second bracket (307) that are respectively bolted to the motion plate (302) and the base plate (301). A first motor (308) and a second motor (309) are respectively mounted on the first bracket (306) and the second bracket (307). The first motor (308) and the second motor (309) are perpendicular to each other on the horizontal plane.

5. A fluorescence immunoassay analyzer according to claim 4, characterized in that: The first motor (308) and the second motor (309) are respectively equipped with a first synchronous pulley group (310) and a second synchronous pulley group (311). The front side of the first synchronous pulley group (310) and the second synchronous pulley group (311) are respectively equipped with two transmission brackets (312). The two transmission brackets (312) of each group are connected by a belt (313). The second synchronous pulley group (311) and its belt (313) are located below the motion plate (302). A clamping plate (314) is installed on the lower side of the middle part of the motion plate (302). The belt (313) of the second synchronous pulley group (311) is clamped between the clamping plate (314) and the motion plate (302).

6. A fluorescence immunoassay analyzer according to claim 5, characterized in that: The detection module (400) includes a fixing block (401) slidably mounted on a support bar (305). One end of the fixing block (401) is clamped to the belt (313) of the first synchronous pulley group (310), and the other end of the fixing block (401) is equipped with a detection mechanism (402).

7. A fluorescence immunoassay analyzer according to claim 6, characterized in that: The incubation system (600) includes an upper plate (601) and a lower plate (602) connected to each other by bolts. Multiple reagent card incubation cavities (603) are reserved between the upper plate (601) and the lower plate (602). The upper plate (601) is provided with corresponding openings (604) on the upper side of the reagent card incubation cavities (603). Ear plates (605) are fixed on both sides of the lower plate (602). The ear plates (605) are fixed to the receiving plate by bolts. An air duct (606) is installed on the lower side of the lower plate (602) by bolts. A temperature monitoring PCB board (607) is installed on the rear side of the upper plate (601) and the lower plate (602). A thermal balance mechanism is installed at the bottom of the lower plate (602). The detection mechanism (402) is located on the upper side of the opening (604).

8. A fluorescence immunoassay analyzer according to claim 1, characterized in that: The motherboard (500) is embedded with a processor module (501), a power module (502), a device driver module (503), a signal conditioning module (504), and a printer module (505). The power module (502) supplies power to each module. The device driver module (503) acquires the fluorescent signal and transmits it to the signal conditioning module (504). The signal conditioning module (504) processes the signal and transmits it to the processor module (501). The processor module (501) is electrically connected to the display screen (201) and controls the display screen (201) and the printer module (505) to output results.

9. A fluorescence immunoassay analyzer according to claim 1, characterized in that: The host (100) also includes a power button (103), a power interface (104), a data interface (105), a network port (106), and a USB interface (107), all of which are located on the outer side of the host (100).

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