A sampling device for pharmaceutical quality control

Abstract

The utility model relates to the technical field of medicine detection, especially is involved in a kind of extraction device for medicine quality management, including base, base one end fixed mounting has mounting bracket, the mounting bracket is provided with extraction pressure subassembly, the extraction pressure subassembly includes the pipe cover that can move up and down, the lower end of the pipe cover is provided with the swivel stand connected with base, the swivel stand is provided with the sealing sampling tube compatible with pipe cover, the port side wall of the sealing sampling tube is provided with branch pipe interface, the mounting pipe is set up and installed on the branch pipe interface, effectively solve the problem that the sample extraction device in the prior art exists operation cumbersome efficiency low.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical testing technology, and in particular to an extraction device for pharmaceutical quality management. Background Technology

[0002] In the fields of pharmaceutical production, distribution, and regulation, drug quality management is a core element in ensuring medication safety, and the accurate extraction of drug samples is a prerequisite for conducting quality management testing (such as component content determination, microbial contamination detection, purity analysis, etc.). Whether it is the factory inspection of pharmaceutical manufacturers, the warehousing acceptance of medical institutions, or the quality sampling inspection of regulatory authorities, all require the extraction of drug samples to rigorously test the quality characteristics of the drugs.

[0003] However, the current sample extraction devices used in drug quality management have problems with cumbersome operation and low efficiency. Traditional extraction devices mostly adopt a single sampling tube design. After each sample is extracted, the sampling tube needs to be manually disassembled, the device cleaned, and a new sampling tube needs to be reinstalled for the next extraction. The operation steps are cumbersome and time-consuming. Especially when facing multiple batches and large quantities of drug sampling inspection, the sampling efficiency is extremely low, making it impossible to complete the quality testing task in a timely manner and affecting the production and circulation progress of drugs. Utility Model Content

[0004] This invention addresses the shortcomings of existing technologies by providing an extraction device for drug quality management, effectively solving the problems of cumbersome operation and low efficiency in existing sample extraction devices.

[0005] The technical solution adopted by this utility model to solve the above problems is as follows: A sampling device for drug quality management includes a base, an mounting frame fixedly mounted on one end of the base, a sampling and pressing assembly on the mounting frame, the sampling and pressing assembly including a tube cap that can move up and down, a rotating frame connected to the base at the lower end of the tube cap, a sealed sampling tube adapted to the tube cap on the rotating frame, a branch pipe interface on the side wall of the sealed sampling tube, and an installation tube sleeved on the branch pipe interface.

[0006] Preferably, a slider is slidably connected to the inner wall of the mounting bracket, a screw is fixedly connected to the inner wall of one end of the slider, and a lead screw that is threadedly engaged with the screw is rotatably connected to the mounting bracket.

[0007] Preferably, an air pump is installed on the slider, the air pump has a rigid pipe at its suction end, and the pipe cover has an exhaust one-way valve connected to the rigid pipe.

[0008] Preferably, the lower end of the tube cap is provided with an annular seal corresponding to the sealing sampling tube, and the annular seal is made of rubber.

[0009] Preferably, the rotating frame includes a mounting plate fixedly installed on the base, a rotating column rotatably connected to the mounting plate, and a fixing frame fixedly connected to the upper end of the rotating column.

[0010] Preferably, the fixing frame is provided with a plurality of mounting holes evenly distributed on it.

[0011] Preferably, both the sealed sampling tube and the installation tube are disposable sampling tubes made of medical-grade PP material.

[0012] Compared with the prior art, this utility model has the following advantages: 1. The rotating frame design enables the cyclic switching of multiple sealed sampling tubes, eliminating the need for frequent manual handling and adjustment of the sampling tube positions, greatly reducing operation time and improving sample extraction efficiency, making it particularly suitable for batch sample testing sites.

[0013] 2. The sealed sampling tube and installation tube are designed for single use. After use, they can be directly treated in accordance with environmental regulations, avoiding the cross-contamination of samples caused by incomplete cleaning during the reuse of traditional sampling devices. At the same time, it also reduces the consumption of water resources and cleaning agents during the cleaning process, which is in line with the concept of environmental protection. Attached Figure Description

[0014] Figure 1 This is a front view of an extraction device for drug quality management according to the present invention; Figure 2 This is a schematic diagram of the pipe cap of an extraction device for drug quality management according to the present invention; Figure 3 This is a schematic diagram of the fixing frame of an extraction device for drug quality management according to the present invention; Figure 4 This is a schematic diagram of the mounting frame of an extraction device for drug quality management according to the present invention; The following are the labels in the diagram: 1-Base, 2-Mounting bracket, 3-Air pump, 4-Rigid pipe, 5-Outlet one-way valve, 6-Bottle cap, 7-Sealed sampling tube, 8-Mounting tube, 9-Branch pipe interface, 10-Fixing bracket, 11-Rotating column, 12-Mounting plate, 13-Annular seal, 14-Mounting hole, 15-Slider, 16-Rotating handle, 17-Lead screw, 18-Screw barrel. Detailed Implementation

[0015] The following are specific embodiments of the present invention, and the technical solution of the present invention will be further described in conjunction with the accompanying drawings. However, the present invention is not limited to these embodiments.

[0016] like Figure 1-4As shown, a sampling device for drug quality management includes a base 1. A mounting frame 2 is fixedly installed at one end of the base 1. A sampling and pressing assembly is provided on the mounting frame 2. The sampling and pressing assembly includes a tube cap 6 that can move up and down. A rotating frame connected to the base 1 is provided at the lower end of the tube cap 6. A sealed sampling tube 7 adapted to the tube cap 6 is provided on the rotating frame. A branch pipe interface 9 is provided on the side wall of the port of the sealed sampling tube 7. An installation tube 8 is sleeved on the branch pipe interface 9.

[0017] In use, the sealed sampling tube 7 is placed on a rotating frame. By rotating the frame, the sealed sampling tube 7 is moved to directly below the tube cap 6. One end of the installation tube 8 is aligned with the branch pipe interface 9 on the side wall of the sealed sampling tube 7 port. The tube is then slowly and forcefully installed, ensuring that the installation tube 8 and the branch pipe interface 9 fit tightly without any looseness or gaps. The installation tube 8 is gently pulled to check. When the center of the tube cap 6 is aligned with the center of the opening of one of the sealed sampling tubes 7 below, the tube cap 6 is moved downwards and inserted into the port of the sealed sampling tube 7. The pressure extraction component is then activated to perform a pressure extraction operation inside the sealed sampling tube 7, creating a negative pressure environment. Under this negative pressure, the liquid medicine to be tested is drawn into the sealed sampling tube 7 through the installation tube 8, completing the sample extraction and collection.

[0018] The mounting bracket 2 has a slider 15 slidably connected to its inner wall, and a screw cylinder 18 is fixedly connected to the inner wall of one end of the slider 15. A lead screw 17 that is threadedly engaged with the screw cylinder 18 is rotatably connected to the mounting bracket 2.

[0019] like Figure 1 As shown, a handle 16 is provided at one end of the lead screw 17. By rotating the lead screw 17 on the mounting bracket 2 through the handle 16, the lead screw 17 is threadedly engaged with the screw cylinder 18 on the inner wall of the slider 15. The rotation of the lead screw 17 will drive the slider 15 to slide up and down along the inner wall of the mounting bracket 2, thereby adjusting the height of the tube cover 6 so that the tube cover 6 is aligned with one of the sealed sampling tubes 7 fixed below.

[0020] An air pump 3 is installed on the slider 15. The air pump 3 has a rigid pipe 4 at its suction end. The pipe cover 6 has an exhaust one-way valve 5 connected to the rigid pipe 4.

[0021] like Figure 1 As shown, the air pump 3 performs a pressure extraction operation on the inside of the sealed sampling tube 7 through the rigid pipe 4 connected to the air intake end and the one-way valve 5 on the tube cover 6, so that a negative pressure environment is formed inside the sealed sampling tube 7, and the rigid pipe 4 can support the tube cover 6.

[0022] The lower end of the tube cap 6 is provided with an annular seal 13 corresponding to the sealed sampling tube 7, and the annular seal 13 is made of rubber.

[0023] like Figure 1 and 2 As shown, the rubber ring seal 13 at the lower end of the tube cap 6 fits tightly with the opening of the sealing sampling tube 7 to achieve a sealing effect and prevent air leakage during subsequent pressure extraction.

[0024] The rotating frame includes a mounting plate 12 fixedly installed on the base 1, a rotating column 11 rotatably connected to the mounting plate 12, and a fixing frame 10 fixedly connected to the upper end of the rotating column 11.

[0025] The mounting bracket 10 is provided with a plurality of mounting holes 14 evenly distributed on it.

[0026] like Figure 1 and 3 As shown, the assembled sealed sampling tubes 7 are placed one by one into the mounting holes 14 of the rotating frame fixing bracket 10 to ensure that the sealed sampling tubes 7 are stably fixed. In addition, the rigid tube 4 supports the tube cap 6, which can prevent shaking or displacement during subsequent operations.

[0027] Both the sealed sampling tube 7 and the installation tube 8 are disposable sampling tubes made of medical-grade PP material.

[0028] like Figure 1 As shown, both the sealed sampling tube 7 and the installation tube 8 are made of medical-grade PP material. This material has excellent chemical stability and sealing properties and will not react chemically with the coating detection medium. The sealed sampling tube 7 and the installation tube 8 are designed for single use and can be directly treated in accordance with regulations after use, avoiding the problem of cross-contamination of samples caused by incomplete cleaning during the reuse of traditional sampling devices.

[0029] The working process of this utility model is as follows: The operator first selects the corresponding number of medical-grade PP disposable sealed sampling tubes 7 and installation tubes 8 according to the type of sealed sampling tube 7, and then installs the installation tube 8 on the branch pipe interface 9 on the side wall of the sealed sampling tube 7 to complete the assembly of the sampling component.

[0030] Place the assembled sealed sampling tubes 7 one by one into the mounting holes 14 of the rotating frame fixing bracket 10 to ensure that the sealed sampling tubes 7 are stably fixed and to avoid shaking or displacement during subsequent operations.

[0031] One end of the lead screw 17 is provided with a handle 16. By rotating the lead screw 17 on the mounting frame 2 through the handle 16, the lead screw 17 is threadedly engaged with the screw cylinder 18 on the inner wall of the slider 15. The rotation of the lead screw 17 will drive the slider 15 to slide up and down along the inner wall of the mounting frame 2, thereby adjusting the height of the tube cover 6 so that the tube cover 6 is aligned with one of the sealed sampling tubes 7 fixed below. Continue adjusting the screw 17 to move the cap 6 downwards and cover the opening of the sealing sampling tube 7. At this time, the rubber ring seal 13 at the lower end of the cap 6 is tightly fitted with the opening of the sealing sampling tube 7 to achieve a sealing effect and prevent air leakage during subsequent pressure extraction.

[0032] The air pump 3 installed on the slider 15 is started. The air pump 3 performs a pressure pumping operation on the inside of the sealed sampling tube 7 through the rigid pipe 4 connected to the air intake end and the one-way valve 5 on the pipe cover 6, so that a negative pressure environment is formed inside the sealed sampling tube 7. Under negative pressure, the liquid medicine to be tested is drawn into the sealed sampling tube 7 through the installation tube 8, thus completing the sample extraction and collection. After a sealed sampling tube 7 has completed sample extraction, the air pump 3 is turned off, the screw 17 is rotated in the opposite direction, and the tube cap 6 is moved upward and disengaged from the sealed sampling tube 7. Rotate the rotating column 11 of the rotating frame, which drives the fixed frame 10 to rotate, and rotate the next empty sealed sampling tube 7 to the position directly below the tube cap 6. Replace the installation tube 8 and repeat the above steps to achieve continuous extraction and processing of multiple samples.

[0033] The specific embodiments described herein are merely illustrative examples illustrating the spirit of this utility model. Those skilled in the art to which this utility model pertains may make various modifications or additions to the described specific embodiments or use similar methods to replace them, without departing from the spirit of this utility model or exceeding the scope defined by the appended claims.

Claims

1. A drug quality management extraction device, comprising a base (1), characterized in that: The base (1) is fixedly mounted with a mounting frame (2) at one end. The mounting frame (2) is provided with a pressure-squeezing assembly. The pressure-squeezing assembly includes a tube cap (6) that can move up and down. The lower end of the tube cap (6) is provided with a rotating frame connected to the base (1). The rotating frame is provided with a sealed sampling tube (7) that is compatible with the tube cap (6). The side wall of the sealed sampling tube (7) is provided with a branch pipe interface (9). An installation tube (8) is sleeved on the branch pipe interface (9).

2. The extraction device for drug quality management according to claim 1, characterized in that: The mounting bracket (2) has a slider (15) slidably connected to its inner wall. A screw (18) is fixedly connected to the inner wall of one end of the slider (15). A screw rod (17) that is threadedly engaged with the screw (18) is rotatably connected to the mounting bracket (2).

3. The extraction device for drug quality management according to claim 2, characterized in that: An air pump (3) is installed on the slider (15), and a rigid pipe (4) is provided at the air intake end of the air pump (3). An air outlet one-way valve (5) connected to the rigid pipe (4) is provided on the pipe cover (6).

4. The extraction device for drug quality management according to claim 3, characterized in that: The lower end of the tube cap (6) is provided with an annular seal (13) corresponding to the sealed sampling tube (7), and the annular seal (13) is made of rubber.

5. The extraction device for drug quality management according to claim 1, characterized in that: The rotating frame includes a mounting plate (12) fixedly installed on the base (1), a rotating column (11) is rotatably connected to the mounting plate (12), and a fixing frame (10) is fixedly connected to the upper end of the rotating column (11).

6. The extraction device for drug quality management according to claim 5, characterized in that: The fixing frame (10) is provided with a number of mounting holes (14) evenly distributed.

7. The extraction device for drug quality management according to claim 1, characterized in that: Both the sealed sampling tube (7) and the installation tube (8) are disposable sampling tubes made of medical-grade PP material.

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