Imaging system for micro-animals
Patent Information
- Application Number
- CN202521582515.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-25
- Publication Date
- 2026-10-13
- Estimated Expiration
- 2035-07-25
AI Technical Summary
[0003]本实用新型的主要目的是提出一种用于微型动物的成像系统,旨在解决传统显微镜下样品成像模糊的问题
[0020]本实用新型的技术方案通过引入平面检测模块与自动调平机构,并结合控制模块的智能控制功能,实现对样品表面倾斜状态的自动检测与补偿。具体而言,控制模块可根据平面检测模块所采集的样品表面多个位置的高度值,计算出当前样品表面的倾斜度,并据此控制各驱动件带动对应的支撑件移动不同的距离。通过调节样品台的姿态,使其沿与样品表面倾斜方向相反的方向倾斜相同的角度,从而有效补偿样品表面的不平整,使样品表面与显微成像模块的光路平面保持平行,确保显微成像模块始终处于最佳焦面位置,减少了因样品表面不平引起的模糊和失焦现象,从而获得清晰、聚焦良好的图像,有效提升了显微成像的清晰度与稳定性。
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Figure CN224851233U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of optical imaging technology, and in particular to an imaging system for micro-animals. Background Technology
[0002] In wastewater treatment, environmental monitoring, and microecology, microorganisms (such as ciliates, rotifers, and oligochaetes) in activated sludge are important biological indicators of wastewater treatment conditions and microecological health. Detailed observation of their morphology and behavior is crucial for studying microorganism community status and diagnosing sludge problems. Currently, imaging observation of microorganisms largely relies on laboratory microscopes, involving manual scanning of samples, manual adjustment of focus, and manual changing of objective lenses to observe morphological and activity characteristics. However, activated sludge samples contain a wide variety of microorganisms, and the sample surface often contains flocs, bubbles, or uneven sludge matrix, resulting in non-horizontal sample planes under traditional microscopes, easily leading to focal plane drift and blurred field of view. Utility Model Content
[0003] The main objective of this invention is to propose an imaging system for micro-animals, which aims to solve the problem of blurry sample imaging under traditional microscopes.
[0004] To achieve the above objectives, the present invention proposes an imaging system for micro-animals, comprising:
[0005] Mounting base;
[0006] A sample stage is provided on the mounting base, and the upper surface of the sample stage is used to place micro-animal samples;
[0007] A microscopic imaging module, located above the sample stage, is used to acquire image information of the sample;
[0008] A planar detection module is located above the sample stage, and the planar detection module is used to collect height values at multiple locations on the sample surface.
[0009] An automatic leveling mechanism includes multiple driving components and multiple supporting components. The multiple driving components are disposed on the mounting base, and the supporting components are connected to the sample stage. The driving components drive the corresponding supporting components to drive the supporting components to move along a first direction.
[0010] The control module is electrically connected to the plane detection module and the automatic leveling mechanism respectively. The control module can control the movement of the support to make the sample surface parallel to the optical path plane.
[0011] In one embodiment, at least three of the supports are distributed circumferentially along the sample stage, and the supports intersect with the connecting lines between the two adjacent supports.
[0012] In one embodiment, the drive is configured as a miniature stepper motor or a piezoelectric driver.
[0013] In one embodiment, the imaging system for micro-animals further includes a base having a detection area and an imaging area distributed along a second direction, a planar detection module disposed on the base corresponding to the detection area, a microscopic imaging module disposed on the base corresponding to the imaging area, and a mounting base movably disposed on the base.
[0014] In one embodiment, the planar detection module includes a mounting bracket and a detection unit. The mounting bracket is connected to the base, and the detection unit is disposed on the mounting bracket corresponding to the detection area. When the sample stage moves to the detection area, the detection unit is located above the sample stage.
[0015] In one embodiment, the imaging system for micro-animals further includes a first movable module extending along the second direction, the mounting base being movably mounted on the first movable module so that the mounting base can move along the second direction.
[0016] In one embodiment, the imaging system for micro-animals further includes a second movable module extending along a third direction, the first movable module being movably mounted on the second movable module so that the mounting base can move along a third direction, the third direction being perpendicular to both the second direction and the first direction.
[0017] In one embodiment, the imaging system for micro-animals further includes an image stitching module electrically connected to the control module and the microscopic imaging module, for stitching together multiple images of the same sample at different locations acquired by the microscopic imaging module.
[0018] In one embodiment, the microscopic imaging module includes a microscope light source, a microscope objective, and a high-definition camera. The microscope light source is detachably disposed directly below the sample, the microscope objective is disposed above the sample, the microscope light source and the microscope objective are positioned opposite each other, and the high-definition camera is disposed directly above the microscope objective.
[0019] In one embodiment, the microscope objective has a magnification of 20 to 40 times, and the high-definition camera is an autofocus HDMI camera with an output resolution of 1920*1080 and a magnification of 20 to 40 times.
[0020] This invention achieves automatic detection and compensation for the tilt of the sample surface by introducing a plane detection module and an automatic leveling mechanism, combined with the intelligent control function of the control module. Specifically, the control module calculates the current tilt of the sample surface based on the height values collected by the plane detection module at multiple locations, and controls each drive component to move its corresponding support component by different distances. By adjusting the posture of the sample stage to tilt it at the same angle in the opposite direction to the tilt of the sample surface, the unevenness of the sample surface is effectively compensated, ensuring that the sample surface remains parallel to the optical path plane of the microscopic imaging module. This ensures that the microscopic imaging module is always in the optimal focal plane position, reducing blurring and defocusing caused by uneven sample surface, thereby obtaining clear, well-focused images and effectively improving the clarity and stability of microscopic imaging. Attached Figure Description
[0021] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.
[0022] Figure 1 A schematic diagram of an embodiment of the imaging system for micro-animals provided by this utility model, with the sample stage in its initial state;
[0023] Figure 2 A schematic diagram of an embodiment of the imaging system for micro-animals provided by this utility model, wherein the sample stage is in an inclined state;
[0024] Figure 3 A top view of the imaging system for micro-animals provided by this utility model.
[0025] Explanation of icon numbers:
[0026] 100, Base; 200, Mounting base; 300, Sample stage; 400, Microscopic imaging module; 500, Planar detection module; 510, Mounting bracket; 520, Detection unit; 600, Automatic leveling mechanism; 610, Driving component; 620, Support component; 700, Control module; 810, First moving module; 820, Second moving module.
[0027] The realization of the purpose, functional features and advantages of this utility model will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation
[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0029] It should be noted that if the embodiments of this utility model involve directional indicators (such as up, down, left, right, front, back, etc.), the directional indicators are only used to explain the relative positional relationship and movement of the components in a specific posture. If the specific posture changes, the directional indicators will also change accordingly.
[0030] Furthermore, if the embodiments of this utility model involve descriptions such as "first" or "second," these descriptions are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined with "first" or "second" may explicitly or implicitly include at least one of those features. Additionally, the use of "and / or" or "and / or" throughout the text includes three parallel solutions. For example, "A and / or B" includes solution A, solution B, or a solution where both A and B are satisfied simultaneously. Furthermore, the technical solutions of the various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. When the combination of technical solutions is contradictory or impossible to implement, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection claimed by this utility model.
[0031] This invention proposes an imaging system for micro-animals.
[0032] Please see Figures 1 to 3In one embodiment of this utility model, the imaging system for micro-animals includes a mounting base 200, a sample stage 300, a microscopic imaging module 400, a plane detection module 500, an automatic leveling mechanism 600, and a control module 700. The sample stage 300 is mounted on the mounting base 200, and its upper surface is used to place micro-animal samples. The microscopic imaging module 400 is located above the sample stage 300 and is used to acquire image information of the samples. The plane detection module 500 is located above the sample stage 300 and is used for... The height values at multiple locations on the sample surface are collected; the automatic leveling mechanism 600 includes multiple driving components 610 and multiple supporting components 620. The multiple driving components 610 are disposed on the mounting base 200, and the supporting components 620 are connected to the sample stage 300. The driving components 610 drive the corresponding supporting components 620 to move the supporting components 620 along a first direction; the control module 700 is electrically connected to the plane detection module 500 and the automatic leveling mechanism 600 respectively. The control module 700 can control the movement of the supporting components 620 so that the sample surface is parallel to the optical path plane.
[0033] This imaging system is used to image and observe microorganisms such as ciliates, rotifers, and oligochaetes in activated sludge samples.
[0034] Specifically, the mounting base 200 serves as the supporting structure for the entire imaging system, used to fix and support other components. The sample stage 300 is mounted on the mounting base 200, and its upper surface is used to support the micro-animal sample to be observed, such as an activated sludge sample containing micro-animals. The microscopic imaging module 400 is located above the sample stage 300, used to acquire image information from the sample, enabling detailed observation of the morphology and behavior of the micro-animals.
[0035] The planar detection module 500 is also positioned above the sample stage 300 to collect height values at multiple locations on the sample surface to obtain surface flatness information and generate a three-dimensional contour map of the sample surface. The planar detection module 500 can employ laser ranging, structured light scanning, or other non-contact high-precision detection technologies to ensure accurate surface morphology data is obtained without disturbing the sample.
[0036] The automatic leveling mechanism 600 includes multiple driving components 610 and multiple support components 620. The driving components 610 are mounted on the mounting base 200, and each driving component 610 is connected to a corresponding support component 620. The support components 620 are connected to the sample stage 300 and are driven to move along a first direction by the driving components 610. Taking the general operating state of the imaging system as an example, the first direction is vertical. Of course, in other operating states of the imaging system, the first direction can be other directions, and there are no further restrictions. By independently adjusting the multiple support components 620, each support component 620 can move a different distance along the first direction, thereby allowing the sample stage 300 to be tilted under the support of support components 620 at different heights.
[0037] The control module 700 is electrically connected to the plane detection module 500 and the automatic leveling mechanism 600, respectively. It receives height data collected by the plane detection module 500 and analyzes the tilt state of the sample surface based on the data. This allows the drive component 610 to move the support component 620 by different distances, tilting the sample stage 300 so that the sample surface remains parallel to the optical path plane of the microscopic imaging module 400. After leveling, the microscopic imaging module 400 can clearly image the sample, avoiding focal plane shift and image blurring caused by uneven sample surfaces. This improves the image quality and makes the morphological and behavioral characteristics of the micro-animals more clearly visible. Furthermore, this imaging system eliminates the need for manual sample leveling or forced flattening with a glass slide, improving the accuracy of sample leveling and avoiding the impact of forced flattening on the behavior of micro-animals.
[0038] Furthermore, compared to repeated manual focusing, the imaging system of this invention, through the automated control of the automatic leveling mechanism 600 and the microscopic imaging module 400, can complete automatic leveling within seconds, significantly shortening the observation time for a single sample, reducing manual intervention, and improving observation efficiency. It is particularly suitable for large-scale, high-throughput imaging analysis of micro-animals. Moreover, the imaging system of this invention can eliminate human focusing errors, ensuring high consistency of microscopic images obtained from different batches and by different operators, facilitating long-term monitoring and quantitative analysis.
[0039] The technical solution of this utility model introduces a plane detection module 500 and an automatic leveling mechanism 600, combined with the intelligent control function of the control module 700, to achieve automatic detection and compensation of the tilt state of the sample surface. Specifically, the control module 700 can calculate the current tilt of the sample surface based on the height values of multiple positions on the sample surface collected by the plane detection module 500, and control each driving component 610 to move the corresponding support component 620 by different distances. By adjusting the posture of the sample stage 300 to tilt at the same angle in the opposite direction to the tilt direction of the sample surface, the unevenness of the sample surface is effectively compensated, keeping the sample surface parallel to the optical path plane of the microscopic imaging module 400. This ensures that the microscopic imaging module 400 is always in the optimal focal plane position, reducing blurring and defocusing caused by uneven sample surface, thereby obtaining clear and well-focused images and effectively improving the clarity and stability of microscopic imaging.
[0040] In one implementation, please refer to Figure 1 and Figure 2 At least three supports 620 are distributed circumferentially along the sample stage 300, and the connecting lines between the supports 620 and the two adjacent supports 620 intersect.
[0041] By employing at least three non-collinear support points to form a stable support structure, the sample stage 300 can be effectively prevented from wobbling or becoming unstable during adjustment. Support members 620, distributed circumferentially along the sample stage 300, can be connected to the peripheral sidewalls of the sample stage 300 or to the lower surface of the sample stage 300, and are spaced apart along the edges of the sample stage 300. Alternatively, support members 620 can be connected to the center of the lower surface of the sample stage 300 to further improve its stability. Each support point can be independently adjusted in height, allowing the sample stage 300 to be fine-tuned in multiple directions, adapting to complex unevenness on the sample surface, and achieving multi-degree-of-freedom and high-precision automatic leveling of the sample stage 300.
[0042] In other embodiments, the support members 620 may also be arranged in an array on the lower surface of the sample stage 300.
[0043] In one embodiment, the support member 620 includes a support rod that connects to the drive member 610. The support rod can be connected to the sample stage 300 via a ball bearing or via a universal joint structure. The support rod can also be magnetically connected to the sample stage 300 via a magnetic ball located at the end of the support rod, or the support rod can be directly magnetically connected to the sample stage 300.
[0044] In one embodiment, the drive 610 is configured as a miniature stepper motor.
[0045] A micro stepper motor is an electric actuator that can convert electrical pulse signals into precise angular or linear displacement. It has advantages such as high control accuracy, fast response speed, and compact structure. As a result, micro stepper motors can achieve precise control of the 620-degree displacement of the support component.
[0046] In another embodiment, the drive 610 is configured as a piezoelectric actuator.
[0047] Piezoelectric actuators utilize the principle that piezoelectric materials deform under the action of an electric field to achieve high-precision and high-stability micro-displacement driving, thus enabling precise control of the 620 micro-displacement of the support component.
[0048] In one implementation, please refer to Figures 1 to 3 The imaging system for micro-animals also includes a base 100, which has a detection area and an imaging area distributed along a second direction. A planar detection module 500 is disposed on the base 100 corresponding to the detection area, and a microscopic imaging module 400 is disposed on the base 100 corresponding to the imaging area. A mounting base 200 is movably disposed on the base 100.
[0049] The detection area and imaging area are distributed along a second direction, which is horizontal in the normal operating state of the imaging system. Of course, the second direction can be other directions in other operating states of the imaging system; this is not a limitation here. The detection area is used to detect the flatness of the sample surface, and the imaging area is used to acquire microscopic images. By separating the detection area and imaging area into different regions of the base 100, the sample detection and imaging processes can be performed independently in different areas, avoiding mutual interference and facilitating automated process control.
[0050] The mounting base 200 is movably mounted on the base 100, meaning that the mounting base 200, which supports the sample stage 300, can move along the second direction on the base 100, thereby enabling automatic movement of the sample between the detection area and the imaging area. Before the sample enters the imaging area, its surface height is first detected in the detection area by the planar detection module 500 to obtain the data required for leveling; then, the mounting base 200 moves to the imaging area to acquire a microscopic image of the leveled sample, ensuring that the microscopic imaging module 400 operates at the optimal focal plane, improving imaging efficiency and image quality; and realizing the automatic positioning, automatic detection, automatic leveling, and automatic imaging process of the sample, improving the automation level and working efficiency of the system.
[0051] In other embodiments, the detection area can also be reused as an imaging area, and the planar detection module 500 and the microscopic imaging module 400 can be moved. When the planar detection module 500 is working, the microscopic imaging module 400 moves to other areas; conversely, when the microscopic imaging module 400 is working, the planar detection module 500 moves to other areas.
[0052] In one implementation, please refer to Figure 1 and Figure 2 The planar detection module 500 includes a mounting bracket 510 and a detection unit 520. The mounting bracket 510 is connected to the base 100. The detection unit 520 is located on the mounting bracket 510 corresponding to the detection area. When the sample stage 300 moves to the detection area, the detection unit 520 is located above the sample stage 300.
[0053] The mounting bracket 510 serves as the support structure for the detection unit 520 and is connected to the base 100 via a detachable or fixed connection, ensuring the stability of the detection unit 520 in space. The detection unit 520 is mounted on the mounting bracket 510 and located directly above the detection area on the base 100, used for non-contact height detection of the sample surface on the sample stage 300. When the sample stage 300 carrying the sample moves to the detection area with the mounting base 200, the detection unit 520 is positioned directly above the sample stage 300, allowing for height scanning of the sample surface and acquisition of height data from multiple points for subsequent leveling control. The detection unit 520 can employ non-contact detection technologies such as laser sensors, structured light sensors, optical interferometers, or capacitive distance sensors to avoid disturbing the sample and ensure the original state of the sample.
[0054] In one implementation, please refer to Figures 1 to 3 The imaging system for micro-animals also includes a first movable module 810 extending in a second direction, and a mount 200 is movably mounted on the first movable module 810 so that the mount 200 can move in the second direction.
[0055] The first moving module 810 is used to move the mounting base 200 along the second direction. The first moving module 810 can be a linear guide and motor drive module, a ball screw module, a linear motor, or a pneumatic slide, etc. The mounting base 200 is movably mounted on the first moving module 810, and the mounting base 200, where the sample stage 300 is located, reciprocates along the second direction through the first moving module 810. When the sample stage 300 moves along the second direction with the mounting base 200, it can sequentially enter the detection area for sample surface height detection and enter the imaging area for microscopic image acquisition. The mounting base 200 drives the sample stage 300 to switch between the detection area and the imaging area through the first moving module 810, without manual intervention, realizing integrated automatic control of sample detection, leveling, and imaging. In addition, the sample stage 300 can also move along the first direction in the imaging area through the first moving module 810 to perform multi-point imaging, realizing automatic multi-point micro-area scanning of the target area at high magnification.
[0056] In one implementation, please refer to Figures 1 to 3The imaging system for micro-animals also includes a second movable module 820 extending along a third direction, wherein a first movable module 810 is movably mounted on the second movable module 820 so that the mounting base 200 can move along a third direction, which is perpendicular to both the second and first directions.
[0057] The second moving module 820 is used to move the mounting base 200 along a third direction. The second moving module 820 can be a guide rail module, a lead screw module, or a linear motor, etc. In the general operating state of the imaging system, the third direction is horizontal and perpendicular to the second direction. That is, the first direction is the Z-axis direction, the second direction is the X-axis direction, and the third direction is the Y-axis direction. Of course, in other operating states of the imaging system, the third direction can also be other directions, which are not limited here. The mounting base 200 can move two-dimensionally within the plane formed by the second and third directions, allowing the sample stage 300 to perform multi-point imaging in the imaging area according to a preset or adaptive microgrid path, achieving multi-point micro-area automatic scanning of the target area on the sample surface at high magnification. Of course, the sample stage 300 can also dynamically adjust the scanning area according to the sample shape, rather than using a fixed microgrid. The imaging system can scan, level, and acquire images at multiple locations on the sample surface, adapting to diverse observation needs. It can also achieve continuous scanning and image stitching of large-sized samples or multiple samples, expanding the imaging field of view and improving the integrity of image information.
[0058] In one embodiment, the imaging system for micro-animals further includes an image stitching module electrically connected to the control module 700 and the microscopic imaging module 400, for stitching together multiple images of the same sample at different locations acquired by the microscopic imaging module 400.
[0059] The image stitching module automatically identifies, aligns, and fuses multiple images acquired by the microscopic imaging module 400 at different locations to generate a complete and continuous stitched image. The image stitching module is electrically connected to the control module 700 and the microscopic imaging module 400, meaning it can receive instructions from the control module 700 and acquire image data acquired by the microscopic imaging module 400. It then automatically performs stitching processing using algorithms such as feature point matching and overlapping area correction. When the sample stage 300 moves along the X and Y axes under the drive of the second moving module 820 and the first moving module 810, the microscopic imaging module 400 performs segmented imaging of different regions of the sample. The image stitching module stitches these images into a complete, continuous, high-resolution image, taking into account both details and global information, enabling high-resolution observation of the entire sample and facilitating the overall analysis of the distribution status of microscopic animals.
[0060] The image stitching module can adapt to objective images with different magnifications and supports multi-scale stitching to meet various observation needs. For example, for complex samples such as activated sludge, the stitched complete image helps to more comprehensively analyze the distribution, morphology, and behavioral characteristics of microorganisms, improving the accuracy of data analysis. The image stitching process can be uniformly scheduled by the control module 700, working in conjunction with sample movement and image acquisition processes to achieve full automation from sample scanning to image generation.
[0061] It is worth mentioning that this invention integrates sample plane detection, automatic leveling, high-magnification scanning, and image stitching into a unified automated process, significantly reducing manual operation and improving the standardization and efficiency of sample detection. Furthermore, after sample leveling, automatic focal plane consistency correction ensures that the focal planes of all images captured from multiple points are consistent, resulting in stitched images without blurring or significant misalignment, thus improving the usability of imaging data and the accuracy of subsequent analysis.
[0062] In one embodiment, the microscopic imaging module 400 includes a microscope light source, a microscope objective, and a high-definition camera. The microscope light source is detachably positioned directly below the sample, the microscope objective is positioned above the sample, and the microscope light source and microscope objective are positioned facing each other. The high-definition camera is positioned directly above the microscope objective.
[0063] The microscope light source is located directly below the sample to provide illumination, enhancing image contrast and clarity. The light source is detachable, allowing for easy replacement with different wavelengths, intensities, or types to suit various observation needs. The microscope objective is positioned directly above the sample, facing the light source, for optical magnification. The light source and objective form a standard vertical illumination path, ensuring uniform and stable light, which is beneficial for obtaining clear, high-contrast images. A high-definition camera is positioned directly above the objective to receive the magnified image signal and convert it into a digital image for output and processing. The high-definition camera features high resolution and a high frame rate, enabling the acquisition of detailed, high-quality images, providing high-quality data support for subsequent image analysis, stitching, and recognition. The microscopic imaging module 400 also supports switching between different magnification microscope objectives, enabling the imaging system to perform frame difference target detection, allowing real-time tracking of microscopic animal movements.
[0064] In one embodiment, the microscope objective lens has a magnification of 20 to 40 times, and the high-definition camera is an autofocus HDMI camera with an output resolution of 1920*1080 and a magnification of 20 to 40 times.
[0065] The microscope objectives have a magnification of 20 to 40x, meaning they offer medium to high magnification, suitable for detailed observation of the morphological details of microscopic animals. The high-definition camera is an autofocus HDMI camera, capable of automatically adjusting the focus based on the sample surface condition to ensure image clarity. It also uses an HDMI interface for real-time transmission of high-definition video signals. The high-definition camera outputs images at a full HD resolution of 1920×1080, meeting the accuracy requirements of subsequent image processing tasks such as image stitching, feature recognition, and behavior analysis, guaranteeing image clarity and detail.
[0066] The above description is merely an exemplary embodiment of the present utility model and does not limit the scope of protection of the present utility model. Any equivalent structural transformations made based on the technical concept of the present utility model and the contents of the present utility model specification and drawings, or direct / indirect applications in other related technical fields, are included within the scope of protection of the present utility model.
Claims
1. An imaging system for micro-animals, characterized in that, include: Mounting base; A sample stage is provided on the mounting base, and the upper surface of the sample stage is used to place micro-animal samples; A microscopic imaging module, located above the sample stage, is used to acquire image information of the sample; A planar detection module is located above the sample stage, and the planar detection module is used to collect height values at multiple locations on the sample surface. An automatic leveling mechanism includes multiple driving components and multiple supporting components. The multiple driving components are disposed on the mounting base, and the supporting components are connected to the sample stage. The driving components drive the corresponding supporting components to drive the supporting components to move along a first direction. The control module is electrically connected to the plane detection module and the automatic leveling mechanism respectively. The control module can control the movement of the support to make the sample surface parallel to the optical path plane.
2. The imaging system for micro-animals as described in claim 1, characterized in that, At least three of the supports are distributed circumferentially along the sample stage, and the support and the connecting line between the two adjacent supports intersect.
3. The imaging system for micro-animals as described in claim 1, characterized in that, The driving component is configured as a miniature stepper motor or a piezoelectric driver.
4. The imaging system for micro-animals as described in claim 1, characterized in that, The imaging system for micro-animals further includes a base having a detection area and an imaging area distributed along a second direction, a planar detection module disposed on the base corresponding to the detection area, a microscopic imaging module disposed on the base corresponding to the imaging area, and a mounting base movably disposed on the base.
5. The imaging system for micro-animals as described in claim 4, characterized in that, The planar detection module includes a mounting bracket and a detection unit. The mounting bracket is connected to the base, and the detection unit is located on the mounting bracket corresponding to the detection area. When the sample stage moves to the detection area, the detection unit is located above the sample stage.
6. The imaging system for micro-animals as described in claim 4, characterized in that, The imaging system for micro-animals further includes a first movable module extending along the second direction, the mounting base being movably mounted on the first movable module so that the mounting base can move along the second direction.
7. The imaging system for micro-animals as described in claim 6, characterized in that, The imaging system for micro-animals further includes a second movable module extending along a third direction, wherein the first movable module is movably mounted on the second movable module so that the mounting base can move along a third direction, which is perpendicular to both the second direction and the first direction.
8. The imaging system for micro-animals as described in claim 7, characterized in that, The imaging system for micro-animals also includes an image stitching module, which is electrically connected to the control module and the microscopic imaging module, and is used to stitch together multiple images of the same sample from different locations acquired by the microscopic imaging module.
9. The imaging system for micro-animals as claimed in claim 1, characterized in that, The microscopic imaging module includes a microscope light source, a microscope objective, and a high-definition camera. The microscope light source is detachably positioned directly below the sample, the microscope objective is positioned above the sample, the microscope light source and the microscope objective are positioned facing each other, and the high-definition camera is positioned directly above the microscope objective.
10. The imaging system for micro-animals as claimed in claim 9, characterized in that, The microscope objective lens has a magnification of 20 to 40 times, and the high-definition camera is an autofocus HDMI camera with an output resolution of 1920*1080 and a magnification of 20 to 40 times.