A three-dimensional reaction chamber for a fluorescent immunoassay analyzer

Abstract

A three-dimensional reaction bin of a fluorescent immunoassay analyzer, which divides the inner part of an incubator into multiple inner cavities, each of which is respectively provided with a plurality of reaction bin groups, each of which is respectively provided with a plurality of reaction chambers, a temperature controller is installed in each reaction chamber, a gripper for grabbing a reagent card is further provided, and a driving device for driving the gripper to move to a position opposite to the different reaction chambers is further provided. The reaction bin has a three-dimensional structure, which can not only increase the number of chambers for placing reagent cards and improve work efficiency, but also enable each reaction bin group to form different incubation environments to meet different detection requirements of different reagent cards. In addition, each reaction chamber is relatively independently arranged, each reaction chamber can place a reagent card, the chamber wall of the chamber can protect and limit the reagent card, the reagent card is more convenient to place, the precision requirement of the equipment is lower, and the reagent cards are not easy to be confused, which is conducive to improving the convenience of reagent card taking and placing, and the accuracy and stability of work.

Description

Technical Field

[0001] This utility model relates to a fully automated fluorescence immunoassay analyzer, and in particular to a reaction chamber structure for accelerating reactions on a fully automated fluorescence immunoassay analyzer. Background Technology

[0002] A fully automated fluorescence immunoassay analyzer is a medical testing device used for human samples (such as blood). The operator places a test tube or vacuum blood collection tube containing the blood sample into the analyzer. The analyzer extracts the sample from the blood collection tube, mixes it with a reagent, and then drops the mixture onto a reagent card. After the reaction is complete, the blood is analyzed based on fluorescence. To improve reaction speed, the analyzer is equipped with a dedicated reaction chamber, with temperature control to provide a constant temperature environment for the reagent card. However, existing fluorescence immunoassay analyzers have a separate reaction chamber. Some chambers can only hold one reagent card, while others can hold multiple cards simultaneously. The former requires a longer waiting time and is less efficient, while the latter requires extremely high precision in handling the reagent cards, leading to potential card mix-ups and resulting in poor accuracy and stability. Utility Model Content

[0003] The purpose of this invention is to provide a three-dimensional reaction chamber so that different reagent cards can use different chambers, thereby increasing the number of reagent cards that can be placed and the convenience of taking them out, and also allowing for better environmental control for different reagent cards.

[0004] The three-dimensional reaction chamber of the fluorescence immunoassay analyzer described in this utility model includes an insulated box with an opening on one side, and several layers of reaction chamber groups are arranged inside the insulated box. Each layer of reaction chamber group is provided with several reaction chambers. The reaction chambers are arranged with openings on the same side as the opening side of the insulated box. A temperature controller is installed in the reaction chamber. Some or all of the adjacent reaction chamber groups are connected by a partition layer that connects the inner walls of each side of the insulated box. The partition layer is provided with a compartment for placing instruments. There is also a gripper for grasping reagent cards and a drive device for driving the gripper to move to the opposite side of different reaction chambers.

[0005] The three-dimensional reaction chamber of the fluorescence immunoassay analyzer described in this utility model has a partitioned insulated box that divides the interior of the insulated box into multiple internal cavities, each of which is equivalent to an insulated box. Different partitions can be installed inside the insulated box as needed, and different temperature control devices can be installed at different locations on the box wall and within each partition. The reaction chamber of each reaction chamber group is then temperature-controlled by different temperature controllers, creating different constant temperature environments to meet the detection needs of different samples. The gripper for grasping reagent cards is aligned with the opening of the insulated box and the opening of the reaction chamber, and, driven by a drive device, can place or remove reagent cards from the reaction chamber. The reaction chamber has a three-dimensional structure, which not only increases the number of compartments for placing reagent cards and improves work efficiency, but also allows each reaction chamber group to form different incubation environments to meet the different detection requirements of different reagent cards. In addition, each reaction chamber is set up relatively independently, and each reaction chamber can hold one reagent card. The chamber walls can protect and limit the reagent card, making it easier to place the reagent card. The equipment accuracy requirements are also lower, and the reagent cards are less likely to be confused, which helps to improve the convenience of reagent card handling, as well as the accuracy and stability of the operation.

[0006] Preferably, one side of the compartment of the partition layer is provided with an opening, and the insulated box is provided with a heat dissipation vent opposite to the opening.

[0007] Preferably, the inner cavity of the reaction chamber is horizontally positioned in the middle, and the opening side of the inner cavity is inclined downwards from the inside out.

[0008] Preferably, the sidewall at the opening of the reaction chamber is inclined.

[0009] Preferably, the gripper includes two clamping plates arranged opposite each other, and a gripper driver that drives at least one of the clamping plates to move up and down.

[0010] Preferably, at least one of the adjacent sides of the two clamping plates is provided with a groove or anti-slip pattern.

[0011] Preferably, the driving device includes a transverse guide rail, a transverse frame that moves along the transverse guide rail, and a transverse drive for driving the transverse frame to move. The transverse frame is equipped with a longitudinal guide rail, a longitudinal frame that moves along the longitudinal guide rail, and a longitudinal drive for driving the longitudinal frame to move. The longitudinal frame is equipped with a vertical guide rail, a vertical frame that moves along the vertical guide rail, and a vertical drive for driving the vertical frame to move. The gripper is mounted on the vertical frame.

[0012] Preferably, the transverse drive, longitudinal drive, and vertical drive each include a drive belt connecting one of the transverse frame, longitudinal frame, or vertical frame, a drive motor for driving the drive belt to move, and a detector for detecting the position of the transverse frame, longitudinal frame, or vertical frame.

[0013] The three-dimensional reaction chamber configuration of the fluorescence immunoassay analyzer described above can further improve the working efficiency and stability of the analyzer. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the three-dimensional reaction chamber of a fluorescence immunoassay analyzer.

[0015] Figure 2 This is a schematic diagram of the connection structure of the insulated box, temperature controller, and partition layer.

[0016] Figure 3 This is a structural diagram of the gripper.

[0017] Figure 4 This is a schematic diagram of the drive device. Detailed Implementation

[0018] The technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. Based on the embodiments of this utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of this utility model.

[0019] It should be noted that if any directional indication (such as up, down, left, right, front, back, top, bottom, inside, outside, vertical, horizontal, longitudinal, counterclockwise, clockwise, circumferential, radial, axial, etc.) is involved in the embodiments of this utility model, the directional indication is only used to explain the relative positional relationship and movement of each component in a certain specific posture (as shown in the figure). If the specific posture changes, the directional indication will also change accordingly.

[0020] If the embodiments of this utility model involve descriptions such as "first" or "second," such descriptions are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, features defined with "first" or "second" may explicitly or implicitly include at least one of those features. Furthermore, the technical solutions of the various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. When the combination of technical solutions is contradictory or impossible to implement, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection claimed by this utility model.

[0021] This invention proposes a three-dimensional reaction chamber for a fluorescence immunoassay analyzer.

[0022] The fluorescence immunoassay analyzer in this embodiment has a three-dimensional reaction chamber, including an insulated box 1 with an opening on one side. The insulated box contains several layers of reaction chamber groups, and each layer of reaction chamber group has several reaction chambers 2. The reaction chambers are located on the same side as the opening of the insulated box. A temperature controller 3 is installed in the reaction chamber. Some or all of the adjacent reaction chamber groups are connected by a partition layer 4 that connects the inner walls of each side of the insulated box. The partition layer contains a compartment for placing instruments. There is also a gripper 5 for grasping reagent cards and a drive device 6 for driving the gripper to move to the opposite side of different reaction chambers.

[0023] like Figure 1-4 As shown, the partitions of the insulated box divide its interior into multiple cavities, each of which functions as an insulated box. Different partitions can be installed inside the insulated box as needed, and different temperature control devices can be installed at different locations on the box walls and within each partition. The reaction chambers of each reaction chamber group are then temperature-controlled by different temperature controllers, creating different constant-temperature environments to meet the testing needs of different samples. The gripper for picking up reagent cards is positioned opposite the opening of the insulated box and the opening of the reaction chamber, and, driven by a drive mechanism, can place reagent cards into or remove them from the reaction chamber. The reaction chamber has a three-dimensional structure, which not only increases the number of compartments for placing reagent cards and improves work efficiency, but also allows each reaction chamber group to form different incubation environments to meet the different detection requirements of different reagent cards. In addition, each reaction chamber is set up relatively independently, and each reaction chamber can hold one reagent card. The chamber walls can protect and limit the reagent card, making it easier to place the reagent card. The equipment accuracy requirements are also lower, and the reagent cards are less likely to be confused, which helps to improve the convenience of reagent card handling, as well as the accuracy and stability of the operation.

[0024] like Figure 2 As shown, one side of the compartment of the partition layer 4 has an opening, and the insulated box 1 has a heat dissipation vent 11 opposite to the opening to dissipate excess heat and maintain the reaction chamber at a constant temperature. The middle of the inner cavity of the reaction chamber 2 is horizontally arranged, and the opening side of the inner cavity is inclined downward from the inside to the outside, so that the end of the reagent card placed in the reaction chamber is suspended, which facilitates the gripping of the hand; at the same time, the side wall of the opening side of the reaction chamber 2 is also inclined, which can guide the placed reagent card, improve the convenience of placing the reagent card and further reduce the accuracy requirements.

[0025] like Figure 3As shown, the gripper 5 includes two clamping plates 51 arranged opposite each other, because the reagent card is a flat, horizontally placed plate. The clamping plates can easily grip the reagent card. There is also a gripper driver 52 that drives at least one of the clamping plates to move up and down. On the adjacent sides of the two clamping plates 51, at least one of them is provided with a groove 53 or an anti-slip pattern 54 to grip the reagent card more stably.

[0026] like Figure 4 As shown, the driving device 6 includes a transverse guide rail 61, a transverse frame 62 that moves along the transverse guide rail, and a transverse drive 63 that drives the transverse frame to move. The transverse frame is equipped with a longitudinal guide rail 64, a longitudinal frame 65 that moves along the longitudinal guide rail, and a longitudinal drive 66 that drives the longitudinal frame to move. The longitudinal frame is equipped with a vertical guide rail 67, a vertical frame 68 that moves along the vertical guide rail, and a vertical drive 69 that drives the vertical frame to move. This forms a three-dimensional moving driving structure, and the gripper 5 is installed on the vertical frame, driving the gripper to achieve three-dimensional movement in the transverse, longitudinal, and vertical directions, thereby accurately gripping or placing reagent cards. The transverse drive 63, longitudinal drive 66, and vertical drive 69 each include a transmission belt connecting one of the transverse frame 62, longitudinal frame 65, or vertical frame 68, a drive motor for driving the transmission belt, and a detector for detecting the position of the transverse frame, longitudinal frame, or vertical frame. This type of drive has a simple and mature structure, and works accurately and stably, which helps to ensure the working stability of the fluorescence immunoassay analyzer.

[0027] The above description is only a preferred embodiment of the present utility model and does not limit the patent scope of the present utility model. All equivalent structural transformations made under the inventive concept of the present utility model using the contents of the present utility model specification and drawings, or direct / indirect applications in other related technical fields, are included within the patent protection scope of the present utility model.

Claims

1. A three-dimensional reaction chamber for a fluorescence immunoassay analyzer, characterized in that: The device includes an insulated box (1) with an opening on one side, which contains several layers of reaction chambers. Each layer of reaction chambers contains several reaction chambers (2). The reaction chambers are located on the same side as the opening of the insulated box. A temperature controller (3) is installed in the reaction chamber. Some or all of the adjacent reaction chambers are connected by a partition layer (4) that connects the inner walls of each side of the insulated box. The partition layer contains a chamber for placing instruments. There is also a gripper (5) for grabbing reagent cards and a drive device (6) for moving the gripper to the opposite side of different reaction chambers.

2. The three-dimensional reaction chamber of the fluorescence immunoassay analyzer according to claim 1, characterized in that: An opening is provided on one side of the compartment of the partition layer (4), and a heat dissipation vent (11) is provided on the insulated box (1) opposite to the opening.

3. The three-dimensional reaction chamber of the fluorescence immunoassay analyzer according to claim 1, characterized in that: The inner cavity of the reaction chamber (2) is horizontally positioned in the middle, and the opening side of the inner cavity is inclined downward from the inside out.

4. The three-dimensional reaction chamber of the fluorescence immunoassay analyzer according to claim 1 or 3, characterized in that: The sidewall of the reaction chamber (2) is inclined at the opening side.

5. The three-dimensional reaction chamber of the fluorescence immunoassay analyzer according to claim 1, characterized in that: The gripper (5) includes two clamping plates (51) arranged opposite each other, and a gripper driver (52) that drives at least one of the clamping plates to move up and down.

6. The three-dimensional reaction chamber of the fluorescence immunoassay analyzer according to claim 5, characterized in that: On the adjacent sides of the two clamps (51), at least one has a groove (53) or an anti-slip pattern (54).

7. The three-dimensional reaction chamber of the fluorescence immunoassay analyzer according to claim 1, 5, or 6, characterized in that: The drive unit (6) includes a transverse guide rail (61), a transverse frame (62) that moves along the transverse guide rail, and a transverse drive (63) that drives the transverse frame to move. The transverse frame is equipped with a longitudinal guide rail (64), a longitudinal frame (65) that moves along the longitudinal guide rail, and a longitudinal drive (66) that drives the longitudinal frame to move. The longitudinal frame is equipped with a vertical guide rail (67), a vertical frame (68) that moves along the vertical guide rail, and a vertical drive (69) that drives the vertical frame to move. The gripper (5) is mounted on the vertical frame.

8. The three-dimensional reaction chamber of the fluorescence immunoassay analyzer according to claim 7, characterized in that: The transverse drive (63), longitudinal drive (66) and vertical drive (69) each include a drive belt connecting one of the transverse frame (62), longitudinal frame (65) or vertical frame (68), a drive motor for driving the drive belt to move, and a detector for detecting the position of the transverse frame, longitudinal frame or vertical frame.

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