A sterile transfer chamber and hot cell for radiopharmaceuticals

Abstract

The utility model relates to a kind of sterile transfer chamber and hot chamber for radioactive medicine, wherein, the sterile transfer chamber is used to receive and transmit radioactive medicine, including lower layer feed bin and upper layer transfer bin;Lifting passage is equipped between lower layer feed bin and upper layer transfer bin, for transmitting shielded can, lifting passage is provided with shielded can opening device;Upper layer transfer bin is equipped with sliding tray and sword type manipulator;Sliding tray is configured to move between upper layer transfer bin and inspection operation area;Sword type manipulator is used to take and place the medicine bottle stored radioactive medicine from shielded can and sliding tray. Through the scheme provided by the utility model, the operator does not need to directly contact the sample when performing relevant sterile inspection on the radioactive medicine, effectively reducing the radiation exposure risk.

Description

Technical Field

[0001] This utility model relates to the field of radiopharmaceutical detection technology, and in particular to a sterile transfer chamber and a hot chamber for radiopharmaceuticals. Background Technology

[0002] In the production and quality control of radiopharmaceuticals, aseptic testing is a crucial step in ensuring product safety. Due to the radiation properties of radiopharmaceuticals, specialized equipment and procedures are required for aseptic testing to guarantee accuracy and the safety of personnel. Traditional aseptic testing processes for radiopharmaceuticals present numerous challenges in the transfer of samples from the production area to the testing area.

[0003] Current methods for transferring radiopharmaceutical samples primarily rely on manual operation. Operators must manually carry shielded containers to move radioactive samples from the production area to the inspection area. This method not only increases the radiation exposure risk for operators but also carries the risk of sample contamination or leakage due to improper handling. Some improved equipment employs simple transfer channels, but lacks automated shielded container opening mechanisms and comprehensive radiation protection measures. During use, operators still need to be in close contact with radioactive samples, failing to fundamentally solve the radiation safety problem.

[0004] Furthermore, existing sample transfer equipment is inadequate in maintaining a sterile environment. Aseptic testing of radiopharmaceuticals requires strict aseptic conditions, but traditional transfer devices often fail to ensure sterility during the transfer process, making them susceptible to microbial contamination and affecting the accuracy of test results.

[0005] Meanwhile, most existing radioactive sample transfer devices have simple structures and single functions, lacking an integrated design concept. They can usually only perform simple sample transfer functions and cannot be organically connected with subsequent aseptic inspection operations, resulting in a fragmented and inefficient inspection process, increasing operational complexity and the risk of cross-contamination. Utility Model Content

[0006] This utility model discloses a sterile transfer chamber and a hot chamber for radiopharmaceuticals, aiming to solve the technical problems existing in the prior art.

[0007] The present invention adopts the following technical solution: On the one hand, this utility model embodiment provides a sterile transfer chamber for radiopharmaceuticals, used for receiving and transferring radiopharmaceuticals, including a lower feeding chamber and an upper transfer chamber; A lifting channel is provided between the lower feeding silo and the upper transfer silo for transferring lead cans. The lifting channel is equipped with a shielded can opening device. The upper transfer chamber is equipped with a sliding tray and a sword-shaped robotic arm; the sliding tray is configured to move between the upper transfer chamber and the inspection area; the sword-shaped robotic arm is used to pick up and put in vials containing radioactive materials from the shielding container and the sliding tray.

[0008] In a preferred embodiment, the lower feed hopper is provided with a first sealing door and a second sealing door; The first sealing door is located on the side of the lower feed hopper and is used to shield the tank from entering or exiting the lower feed hopper. The second sealing door is located on the top surface of the lower feeding silo, through which the lifting channel passes, and is used to transfer the shielded tank between the lower feeding silo and the upper transfer silo.

[0009] In a preferred embodiment, an interlocking mechanism is provided between the first sealing door and the second sealing door, and the interlocking mechanism is configured such that when either sealing door is opened, the other sealing door is locked.

[0010] In a preferred embodiment, the lower feeding hopper is further provided with a bidirectional moving device, which includes a first moving mechanism for realizing horizontal lateral movement and a second moving mechanism for realizing vertical longitudinal movement. The first moving mechanism can move laterally and extend outside the first sealing door for the shielding container to be placed or removed. The second moving mechanism can move vertically within the lifting channel to control the up-and-down movement of the shielded tank between the lower feeding hopper and the upper transfer hopper.

[0011] In a preferred embodiment, the shielding can opening device is disposed on the first moving mechanism, including a cover positioning mechanism and a cover opening driving mechanism; the cover positioning mechanism is used to lock and fix the cover of the shielding can; the cover opening driving mechanism is disposed below one side of the cover positioning mechanism and is fixedly connected to the cover positioning mechanism, and is used to drive the cover positioning mechanism to move vertically in the longitudinal direction to open the cover of the shielding can.

[0012] In a preferred embodiment, the sliding tray includes a tray body and a tray guide rail; The tray body has a medicine bottle placement area; the tray guide rail is used to support the tray body and guide its smooth movement.

[0013] In a preferred embodiment, the pallet guide rail extends horizontally and terminates at one side wall of the upper transfer compartment, and the upper transfer compartment has a transfer window in the extension termination area of ​​the pallet guide rail, through which the pallet body can be output.

[0014] In a preferred embodiment, the sword-shaped robotic arm includes a gripping part and an operating part. The gripping part is disposed inside the upper transfer compartment and is used to at least grip medicine bottles and push a sliding tray. The operating part is disposed outside the upper transfer compartment and is used to control the specific actions of the gripping part.

[0015] In a preferred embodiment, the upper transfer chamber further includes an independent exhaust system and a sterilization system; An independent exhaust system is used to control air cleanliness to meet Class B standards; The sterilization system is used to sterilize the environment and radioactive drugs in the sterile transfer room to ensure a sterile environment.

[0016] Secondly, this utility model embodiment also provides a hot chamber for radiopharmaceuticals, including a sterile transfer chamber for radiopharmaceuticals as described in any of the preceding claims, and a sterile semi-automatic inspection chamber, wherein the sterile semi-automatic inspection chamber and the sterile transfer chamber are sealed and connected, and a sliding tray can reciprocate between the two. One embodiment of the above-described utility model has the following advantages or beneficial effects: This invention primarily provides a sterile transfer chamber for radiopharmaceuticals. Through a layered design of a lower feeding chamber and an upper transfer chamber, combined with a shielded container opening device in the lifting channel, the safe transfer and automatic opening of radiopharmaceuticals are achieved. The solution provided by this invention eliminates the need for operators to directly contact radioactive samples, effectively reducing the risk of radiation exposure. Simultaneously, the interlocking mechanism between the first and second sealing doors ensures the safety and airtightness of the entire transfer process, preventing leakage and cross-contamination of radioactive materials.

[0017] This invention's sterile transfer chamber is equipped with a sword-shaped robotic arm and a sliding tray, enabling the removal of vials from the shielded container and their transfer to the inspection area without manual contact, significantly improving work efficiency. The sterilization system and independent exhaust system of the upper transfer chamber ensure that the air cleanliness meets Class B standards, providing ideal environmental conditions for the transfer of radioactive drugs. Overall, this invention not only solves the radiation safety problems associated with traditional manual operations but also ensures the sterility of the inspection environment through automated transfer and sterilization, providing comprehensive technical support for the quality control of radioactive drugs. Attached Figure Description

[0018] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below, forming part of this utility model. The illustrative embodiments of this utility model and their descriptions explain this utility model and do not constitute an improper limitation of this utility model. In the drawings: Figure 1 This is a schematic diagram of the overall structure of a hot chamber for radiopharmaceuticals provided in a preferred embodiment of the present invention. Figure 2 This is a top view of the internal structure of a hot chamber for radiopharmaceuticals provided in a preferred embodiment of the present invention. Figure 3 This is a schematic diagram showing the internal structure of the sterile transfer room and the sterile semi-automatic examination room provided in a preferred embodiment of the present invention. Figure 4 This is a schematic diagram of the internal structure of a sterile transfer chamber provided in a preferred embodiment of the present invention; Figure 5 This is a schematic diagram of the upper transfer chamber provided in a preferred embodiment of the present invention; Figure 6 This is a front view of the upper transfer chamber provided in a preferred embodiment of the present invention. Figure 7 This is a schematic diagram of the internal structure of the upper transfer chamber provided in a preferred embodiment of the present invention; Figure 8 This is a schematic diagram of the structure of a sliding tray provided in a preferred embodiment of the present invention.

[0019] Explanation of reference numerals in the attached figures: Aseptic transfer chamber 1, upper transfer chamber 11, sliding tray 111, tray body 1111, tray guide rail 1112, transfer window 112, lower feed chamber 12, first sealing door 121, second sealing door 122, first moving mechanism 123, second moving mechanism 124, cover positioning mechanism 125, cover opening drive mechanism 126, lifting channel 127, isolation sealing cover 128, sword-type robotic arm 2, clamping part 21, operating part 22, aseptic semi-automatic inspection chamber 3. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of this utility model clearer, the technical solutions of this utility model will be clearly and completely described below in conjunction with specific embodiments and corresponding drawings. In the description of this utility model, it should be noted that the term "or" is generally used to include the meaning of "and / or," unless otherwise expressly stated otherwise.

[0021] In the description of this application, the terms "first," "second," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0022] Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0023] refer to Figures 1-8To address the technical problems existing in the prior art, this utility model provides a sterile transfer chamber 1 for radiopharmaceuticals. This sterile transfer chamber 1 enables contactless opening of shielding containers and contactless removal of medicine bottles, effectively reducing the risk of radiation exposure to operators during the sterile inspection of radiopharmaceuticals.

[0024] In this embodiment, the shielding container is a protective container specifically designed for the storage and transportation of radiopharmaceuticals. Its main body is made of high-purity lead or other radioactive shielding materials, providing significant radiation shielding. The shielding container typically consists of two parts: a main body and a lid. The lid and main body are detachably connected to ensure that radiopharmaceuticals do not leak during storage and transportation, while also preventing radiation leakage. A lead container is a typical example of a shielding container.

[0025] Furthermore, in this embodiment, the vial is used to store radiopharmaceuticals. The vial is preferably a vial, a sealed glass container specifically used in the pharmaceutical field, primarily for holding injectable medications to ensure the medication remains sterile during storage and transportation. In the application scenario of this embodiment, the vial is mainly used to hold radiopharmaceutical samples that require sterility testing.

[0026] The aseptic transfer chamber 1 provided in this embodiment is a key component of the aseptic testing hot chamber for radiopharmaceuticals. Its main function is to safely receive lead containers containing radiopharmaceuticals, automatically open the containers without direct human contact, remove the vials, and transfer them to the testing area. This transfer chamber design allows for subsequent aseptic testing of radiopharmaceuticals in a strictly controlled aseptic environment. These subsequent operations include sample extraction and culture medium inoculation, thus ensuring operator safety while guaranteeing compliance with relevant standards and regulations.

[0027] refer to Figures 2-7 In a preferred embodiment, the aseptic transfer chamber 1 includes a lower feeding chamber 12 and an upper transfer chamber 11. A lifting channel 127 is provided between the lower feeding chamber 12 and the upper transfer chamber 11. The lifting channel 127 is equipped with a shielding can opening device for transferring shielding cans. The upper transfer chamber 11 is equipped with a sliding tray 111 and a sword-type robotic arm 2. The sliding tray 111 is configured to move between the upper transfer chamber 11 and the inspection operation area. The sword-type robotic arm 2 is used to pick up and put in vials containing radioactive drugs from the lead can and the sliding tray 111.

[0028] Specifically, by configuring the aseptic transfer chamber 1 as an upper and lower compartment, the external environment can be effectively isolated from the internal aseptic operating environment, minimizing the risk of cross-contamination and radioactive material leakage. The lower feed chamber 12 serves as a primary barrier, receiving lead containers from the external environment, while the upper transfer chamber 11 maintains a higher level of cleanliness, ensuring that radioactive pharmaceuticals are transferred and processed in a sterile environment. Furthermore, by setting up an isolation layer with sufficient lead equivalent between the two independent spaces, the leakage pathways of radioactive materials are effectively blocked, thus forming a multi-barrier protection system that further enhances the radiation safety level during operation.

[0029] refer to Figure 4 In a preferred embodiment, the lower feeding hopper 12 is provided with a first sealing door 121 and a second sealing door 122; the first sealing door 121 is provided on the side of the lower feeding hopper 12 for placing lead cans into or out of the lower feeding hopper 12; the second sealing door 122 is provided on the top surface of the lower feeding hopper 12 for the passage of the lifting channel 127 for transferring lead cans between the lower feeding hopper 12 and the upper transfer hopper 11.

[0030] Preferably, an interlocking mechanism is provided between the first sealing door 121 and the second sealing door 122, and the interlocking mechanism is configured such that when either sealing door is opened, the other sealing door is locked.

[0031] In a preferred embodiment, both the first sealing door 121 and the second sealing door 122 are configured as multi-layer composite structures, including an outer lead protective layer and an inner airtight sealing layer. The outer lead protective layer is made of high-purity lead material, which can effectively block the radiation released by radioactive drugs. The inner airtight sealing layer is made of polymer material and is equipped with an inflatable sealing ring on its outer periphery, which can maintain a negative pressure environment inside the cabin under sealed conditions and prevent the diffusion of particles and aerosols.

[0032] In one optional embodiment, the interlocking mechanism of the first sealing door 121 and the second sealing door 122 adopts a structure combining mechanical linkage and electrical control. The interlocking mechanism includes a position sensor, an electronically controlled locking device, and a mechanical linkage system. The position sensor is used to monitor the opening and closing status of the first sealing door 121 or the second sealing door 122 in real time. The electronically controlled locking device controls the extension and retraction of the locking pin according to the signal from the position sensor to lock or unlock the sealing door. The mechanical linkage system forcibly locks the other sealing door through physical connection when one sealing door is opened, forming a double insurance.

[0033] In another alternative implementation, the interlocking mechanism can also be integrated into the control system, enabling intelligent management of the sealed door status through a programmable logic controller (PLC). It can also be linked with a radiation monitoring system to automatically trigger the sealing door to lock when an abnormal radiation level is detected, further improving the system's security.

[0034] It should be understood that those skilled in the art can select various interlocking mechanisms disclosed in the prior art, such as pneumatic interlocking systems, electromagnetic interlocking systems or electronic interlocking systems, to realize the linkage relationship between the first sealing door 121 and the second sealing door 122, according to specific application requirements. This utility model does not limit the specific implementation method and structure of the interlocking mechanism.

[0035] refer to Figures 4-7 In a preferred embodiment, the lower feeding hopper 12 is further provided with a bidirectional moving device, which includes a first moving mechanism 123 for horizontal movement and a second moving mechanism 124 for vertical movement. The first moving mechanism 123 can move laterally and extend to the outside of the first sealing door 121 for lead cans to be picked up and put in. The second moving mechanism 124 can move vertically within the lifting channel 127 to control the up and down movement of the lead cans between the lower feeding hopper 12 and the upper transfer hopper 11.

[0036] In a preferred embodiment, the first moving mechanism 123 adopts a pull-out slide rail structure, including a fixed guide rail and a movable tray disposed within the lower feeding hopper 12. The fixed guide rail is preferably installed at the bottom of the lower feeding hopper 12, and the movable tray is slidably connected to the fixed guide rail. The tray has a groove structure for placing lead cans, the outer edge of which matches the outer diameter of the bottom of the lead can for stable positioning. The center of the groove is hollowed out, providing a passage for the second moving mechanism 124, allowing the second moving mechanism 124 to extend upwards from the hollowed-out portion, contact the bottom of the lead can, and perform a lifting operation. The first moving mechanism 123 can smoothly extend outwards when the first sealing door 121 is opened, forming a working platform convenient for operators to place lead cans. After the lead cans are placed, the first moving mechanism 123 can be retracted into the lower feeding hopper 12 by electric or manual means.

[0037] In a preferred embodiment, the second moving mechanism 124 consists of a drive motor, a transmission rod, and a lifting platform. Specifically, the drive motor can drive the transmission rod to rotate, and the threaded structure on the transmission rod meshes with the lifting platform, converting the rotational motion into the vertical motion of the lifting platform. The upper end of the lifting platform is provided with a support structure that matches the bottom of the lead can. When the lifting platform rises, it can pass through the hollow part of the tray groove, contact and lift the lead can, realizing the vertical movement of the lead can within the lifting channel 127.

[0038] In a preferred embodiment, the lifting channel 127 is configured as a longitudinally extending circular channel with an inner diameter slightly larger than the outer diameter of a standard lead can, to ensure that the lead can does not get stuck during lifting. In a more preferred embodiment, the top of the lifting channel 127 is also provided with an isolation sealing cover 128. When the lead can rises from the lifting channel 127 and it is necessary to further remove the vial inside, this isolation sealing cover 128 can be opened first by the sword-type robotic arm 2.

[0039] In a preferred embodiment, the shielding can opening device is disposed on the support plate of the first moving mechanism 123, including a cover positioning mechanism 125 and a cover opening driving mechanism 126; the cover positioning mechanism 125 is used to lock and fix the cover of the lead can; the cover opening driving mechanism 126 is disposed below one side of the cover positioning mechanism 125 and is fixedly connected to the cover positioning mechanism 125, and is used to drive the cover positioning mechanism 125 to move vertically in the longitudinal direction to open the cover of the lead can.

[0040] In a preferred embodiment, the lid positioning mechanism 125 is configured as a semi-circular claw, the surface of which is covered with an elastic material, which can fit tightly against the outer edge of the lid of the lead can, so as to achieve precise positioning and stable clamping of the lid, and ensure that the lid will not slip off during the opening process.

[0041] In a preferred embodiment, the lid-opening drive mechanism 126 adopts a linear sliding structure with a slider at its bottom. The first moving mechanism 123 has a matching slide rail on its support plate. The slide rail enables the lid-opening drive mechanism 126 to achieve two modes of movement on the support plate: one is to achieve vertical lifting and lowering through a built-in small electric cylinder, which drives the lid positioning mechanism 125 to move upward to open the lead can lid; the other is to quickly retreat after completing the lid-opening operation through a horizontal sliding function, creating an interference-free channel for the upward transmission of the lead can body.

[0042] By setting up a shielded container opening device, the lead container opening process is fully automated, requiring no manual intervention and effectively reducing the radiation exposure risk for operators.

[0043] like Figure 8 In a preferred embodiment, the sliding tray 111 in the upper transfer chamber 11 includes a tray body 1111 and a tray guide rail 1112. The tray body 1111 is provided with a vial placement area. The tray guide rail 1112 is used to support the tray body 1111 and guide its smooth movement. Preferably, the tray guide rail 1112 extends horizontally and terminates at one side wall of the upper transfer chamber 11. The upper transfer chamber 11 is provided with a transfer window 112 in the extension termination area of ​​the tray guide rail 1112, through which the tray body 1111 can be output outward from the transfer window 112.

[0044] In a preferred embodiment, the vial placement area on the tray body 1111 adopts a groove design and is equipped with multiple circular slots of different diameters to accommodate the placement needs of vials of different sizes, ensuring that the vials remain stable and do not tip over during the transfer process.

[0045] In a preferred embodiment, the pallet guide rail 1112 is fixed to the bottom of the upper transfer compartment 11, and its extension direction is consistent with that of the transfer window 112. The pallet guide rail 1112 is also preferably provided with a limiting mechanism to prevent the pallet body 1111 from exceeding the predetermined travel range during movement. The pallet guide rail 1112 extends horizontally to the side wall of the upper transfer compartment 11, and precisely aligns with the transfer window 112 provided on the side wall.

[0046] It should be noted that the destination of the tray body 1111 output from the transfer window 112 is not the external environment, but the sterile semi-automatic inspection chamber 3 connected to the upper transfer chamber 11. The sterile semi-automatic inspection chamber 3 and the upper transfer chamber 11 together constitute the core operating area of ​​the radiopharmaceutical sterile inspection hot chamber system, and the two are connected in an airtight manner through the transfer window 112. This design ensures that the radioactive sample is always in a controlled sterile environment throughout the inspection process, avoiding direct contact with the external environment, thereby effectively preventing the risk of microbial contamination and radioactive material leakage.

[0047] like Figure 2 In a preferred embodiment, the sword-type robotic arm 2 includes a gripping part 21 and an operating part 22. The gripping part 21 is disposed inside the upper transfer chamber 11 and is capable of gripping vials, pushing the sliding tray 111, and opening the isolation sealing cover 128 at the top of the lifting channel 127. The operating part 22 is disposed outside the upper transfer chamber 11 and is used to control the specific actions of the gripping part 21. It should be noted that, regarding Figure 2 The multiple sword-shaped robotic arms 2 shown are actually illustrations of the same sword-shaped robotic arm 2 in different moving positions.

[0048] Specifically, the sword-shaped robotic arm 2 is a remote mechanical device specifically designed for manipulating items in confined environments. Its structure typically includes an external control lever, a sealed connector, an internal extension arm, and an end effector. The external control lever, serving as the operating part 22, is operated by an operator outside the sterile transfer chamber 1. The internal extension arm, serving as the gripping part 21, extends into the sterile transfer chamber 1, with an end effector specifically designed for gripping items. The sealed connector is located between the operating part 22 and the gripping part 21, passing through the wall of the upper transfer chamber 11 to ensure isolation between the internal and external environments. The entire sword-shaped robotic arm 2 allows the operator to control the movement of the internal gripping part 21 through precise hand movements, enabling precise gripping and displacement of items within the sterile transfer chamber 1.

[0049] It should be noted that this embodiment does not limit the specific structure of the sword-type robotic arm 2. Those skilled in the art can select an appropriate sword-type robotic arm structure from the existing technology and apply it to this utility model according to actual needs. There are already many mature sword-type robotic arm products on the market that can meet the needs of handling radioactive materials. It is only necessary to make appropriate selections and adjustments according to the functional requirements of this embodiment.

[0050] It is worth noting that the portion of the sword-shaped robotic arm 2 that passes through the wall of the upper transfer chamber 11 employs a combination of flexible sealing rings and bearings to ensure the sealing and integrity of the sterile environment. This also ensures that the robotic arm's movement in all directions does not disrupt the negative pressure and sterile conditions within the upper transfer chamber 11. In this embodiment, the front of the upper transfer chamber 11 is also equipped with at least one observation window. This window is made of radiation-resistant lead glass, offering high transparency and excellent radiation shielding performance. This allows the operator to clearly observe the movement and position of the sword-shaped robotic arm 2, facilitating precise control of its direction of movement and operational actions, thereby improving operational accuracy and safety.

[0051] In a preferred embodiment, the upper transfer chamber 11 further includes an independent exhaust system and a sterilization system. The independent exhaust system is used to control the air cleanliness to meet the Class B standard. The sterilization system is used to sterilize the environment and radioactive drugs in the sterile transfer chamber 1 to ensure a sterile environment.

[0052] It should be understood that the embodiments of this utility model do not strictly limit the specific structure, installation location, equipment specifications, etc. of the independent exhaust system and sterilization system. Those skilled in the art can make appropriate adjustments and optimizations to these systems according to actual application scenarios, space constraints, budget requirements, and the level of technological development.

[0053] refer to Figures 1-3 In this embodiment of the present invention, a hot chamber for radiopharmaceuticals is further provided, including the above-mentioned sterile transfer chamber 1 and a sterile semi-automatic inspection chamber 3 sealed and connected thereto. The two are connected by a transfer window 112, and a sliding tray 111 can move back and forth between the two.

[0054] Specifically, the main function of the sterile semi-automatic inspection room 3 is to provide a working environment that meets the requirements of sterile operation and effectively shields the radiation of radioactive materials, so that operators can safely complete the sterile inspection of radioactive drugs. In this embodiment, its structure is not specifically limited.

[0055] The embodiments of the present invention have been described above with reference to the accompanying drawings. However, the present invention is not limited to the specific embodiments described above. The specific embodiments described above are merely illustrative and not restrictive. Those skilled in the art can make many other forms under the guidance of the present invention without departing from the spirit and scope of the claims, and all of these forms are within the protection scope of the present invention.

Claims

1. A sterile transfer room for radiopharmaceuticals, characterized in that, Used for receiving and transferring radiopharmaceuticals, including a lower feed silo and an upper transfer silo; A lifting channel is provided between the lower feeding hopper and the upper transfer hopper for transferring the shielded container; the lifting channel is equipped with a shielded container opening device. The upper transfer chamber is equipped with a sliding tray and a sword-shaped manipulator; the sliding tray is configured to move between the upper transfer chamber and the inspection operation area; the sword-shaped manipulator is used to pick up and put in vials containing radioactive drugs from the shielding container and the sliding tray.

2. The sterile transfer room for radiopharmaceuticals according to claim 1, characterized in that, The lower feeding hopper is equipped with a first sealing door and a second sealing door; The first sealing door is located on the side of the lower feed hopper and is used to shield the tank from entering or exiting the lower feed hopper; The second sealing door is located on the top surface of the lower feeding hopper, through which the lifting channel passes, and is used to transfer the shielding can between the lower feeding hopper and the upper transfer hopper.

3. The sterile transfer room for radiopharmaceuticals according to claim 2, characterized in that, An interlocking mechanism is provided between the first sealed door and the second sealed door, and the interlocking mechanism is configured such that when either sealed door is opened, the other sealed door is locked.

4. The sterile transfer room for radiopharmaceuticals according to claim 3, characterized in that, The lower feeding hopper is also equipped with a bidirectional moving device, which includes a first moving mechanism for realizing horizontal movement and a second moving mechanism for realizing vertical movement. The first moving mechanism can move laterally and extend outside the first sealing door for the shielding container to be placed or removed; The second moving mechanism is capable of vertical movement within the lifting channel to control the up-and-down movement of the shielded tank between the lower feeding hopper and the upper transfer hopper.

5. The sterile transfer room for radiopharmaceuticals according to claim 4, characterized in that, The shielding can opening device is mounted on the first moving mechanism and includes a cover positioning mechanism and a cover opening driving mechanism. The cover positioning mechanism is used to lock and fix the cover of the shielding can; The lid opening drive mechanism is located below the lid positioning mechanism on one side and is fixedly connected to the lid positioning mechanism. It is used to drive the lid positioning mechanism to move vertically in the longitudinal direction to open the lid of the shielding can.

6. The sterile transfer room for radiopharmaceuticals according to claim 1, characterized in that, The sliding tray includes a tray body and a tray guide rail; The tray body is provided with a medicine bottle placement area; the tray guide rail is used to support the tray body and guide its smooth movement.

7. The sterile transfer room for radiopharmaceuticals according to claim 6, characterized in that, The pallet guide rail extends horizontally and terminates at one side wall of the upper transfer compartment. The upper transfer compartment has a transfer window in the extension termination area of ​​the pallet guide rail, and the pallet body can be output outward from the transfer window.

8. The sterile transfer room for radiopharmaceuticals according to claim 7, characterized in that, The sword-shaped robotic arm includes a gripping part and an operating part. The gripping part is located inside the upper transfer compartment and is used to at least grip medicine bottles and push the sliding tray. The operating part is located outside the upper transfer compartment and is used to control the specific actions of the gripping part.

9. The sterile transfer room for radiopharmaceuticals according to claim 1, characterized in that, The upper transfer chamber also includes an independent exhaust system and a sterilization system; The independent exhaust system is used to control air cleanliness. The sterilization system is used to sterilize the environment and radioactive drugs in the sterile transfer chamber.

10. A hot chamber for radiopharmaceuticals, characterized in that, The device includes a sterile transfer room for radiopharmaceuticals as described in any one of claims 1-9, and further includes a sterile semi-automatic inspection room, wherein the sterile semi-automatic inspection room is in sealed communication with the sterile transfer room, and the sliding tray can reciprocate between the two.

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