A solution concentration and filling apparatus

Abstract

This utility model discloses a solution concentration and filling device, including a concentration module and a packaging module. The concentration module includes an evaporation assembly with an evaporator, a heating device for supplying heat to the evaporator, and a negative pressure generating assembly. The evaporator contains an evaporation space for solution concentration, and the negative pressure generating assembly works in conjunction with the evaporator to create negative pressure within the evaporation space. This negative pressure environment significantly shortens the time it takes for the solution to reach its boiling point, accelerates the water evaporation rate, and greatly improves overall production efficiency. The packaging module includes a feeding mechanism for providing consumables and a processing assembly for making packaging bags from the consumables. The evaporator works in conjunction with the packaging module to transport the concentrated solution into the packaging bags made by the processing assembly. This equipment integrates concentration and filling functions, allowing for immediate filling of the concentrated solution, avoiding intermediate transfers and waiting times; reducing the possibility of cross-contamination of the solution and improving product quality and production efficiency.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical preparation production and processing, and more specifically, to a solution concentration and filling equipment. Background Technology

[0002] Medicinal liquids are active liquids obtained from natural medicinal materials (such as plants, animals, and minerals) through processes such as extraction, decoction, or osmosis. They are widely used in the pharmaceutical, health product, and food industries. Their core components include alkaloids, polysaccharides, volatile oils, and other effective substances, but they typically have a high water content (70%-90%). High water content can cause the following problems: 1. Poor user experience: Water dilutes the effective ingredients, resulting in reduced efficacy for the same volume, requiring more liquid to reach the required dosage. Overdose can easily cause bloating, nausea, and other physiological discomfort. 2. High storage risk: Moisture creates a suitable environment for the growth of microorganisms (such as bacteria and mold), easily leading to spoilage and deterioration of the medicinal liquid. Long-term storage may also cause stratification, precipitation, or crystallization, affecting the uniformity of administration. 3. Inconvenient to carry: High water content increases packaging volume, not only increasing transportation costs but also making the packaging more susceptible to damage during transport due to compression or collision.

[0003] Drug concentration and filling are core steps in pharmaceutical manufacturing, and their combined efficiency and control precision directly impact product quality, production efficiency, and compliance. In traditional processes, atmospheric pressure evaporation equipment heats the drug solution at high temperatures, concentrating it after water evaporates. However, high temperatures can damage heat-sensitive components (such as proteins and enzymes), affecting product quality. Simultaneously, atmospheric pressure evaporation requires raising the drug solution to its boiling point, a process that takes considerable time, leading to reduced production efficiency. Traditional filling relies on semi-automatic or manual operation, which is not only inefficient but also prone to cross-contamination of the drug solution, further affecting product quality. Utility Model Content

[0004] This utility model overcomes the shortcomings of the prior art and provides a solution concentration and filling equipment with simple structure, reasonable design, higher production efficiency and higher product quality.

[0005] To solve the above-mentioned technical problems, the technical solution of this utility model is as follows:

[0006] A solution concentration and filling device includes a concentration module and a packaging module. The concentration module includes an evaporation assembly with an evaporator, a heating device for supplying heat to the evaporator, and a negative pressure generating assembly. The evaporator has an evaporation space for evaporating and concentrating the solution, and the negative pressure generating assembly works with the evaporator to create a negative pressure within the evaporation space. The packaging module includes a feeding mechanism for providing consumables and a processing assembly for forming packaging bags from the consumables. The evaporator works with the packaging module to deliver the concentrated solution into the packaging bags formed by the processing assembly.

[0007] Furthermore, a heating space is provided inside the evaporator; the heating space and the evaporation space are relatively sealed; the heating space surrounds the evaporation space and is filled with a heat-conducting medium; a heating device is installed in the heating space to control the temperature of the heat-conducting medium.

[0008] Furthermore, the evaporator is provided with a solution inlet, a solution outlet, and a steam outlet communicating with the evaporation space; the negative pressure generating component includes a vacuum pump, which cooperates with the steam outlet to extract gas in the evaporation space to form a negative pressure environment in the evaporation space; a solution inlet is provided at the solution inlet, and a solution outlet is provided at the solution outlet, which passes through the heating space and protrudes from the evaporator; both the solution inlet and the solution outlet are provided with solenoid valves to control their conduction state.

[0009] Furthermore, the concentration module also includes a condenser and a water collection tank; the condenser is connected to and communicates with the evaporator and the water collection tank; the vacuum pump is connected to and cooperates with the water collection tank, thereby drawing the steam generated by the evaporation component into the condenser, and then drawing the condensate formed by the steam in the condenser into the water collection tank.

[0010] Furthermore, a foam sensor is installed on the evaporator, and the sensing part of the foam sensor is located in the evaporation space; the condenser and the water collection tank are connected by a water collection connection pipe, and a vent valve that allows atmospheric pressure air to be introduced is also installed at the water collection connection pipe.

[0011] Furthermore, the evaporator is equipped with a heating inlet and a heating outlet that communicate with the heating space for charging and discharging the heat transfer medium, and inlet valves and outlet valves are provided at both of them; the evaporator is also equipped with a heating pressure relief port that communicates with the heating space.

[0012] Furthermore, an extraction and distribution module is provided between the concentration module and the packaging module, which includes an extraction pump, a final liquid tank, and a distribution pump; the final liquid tank is provided with a final liquid measurement space, and the final liquid tank is provided with a final liquid measurement device for measuring the solution volume; the final liquid tank is provided with a concentration inlet and a concentration outlet communicating with the final liquid measurement space, and a concentration inlet valve and a concentration outlet valve are respectively provided at the two; the extraction pump cooperates with the concentration inlet valve and the solution outlet pipe; the distribution pump cooperates with the concentration outlet valve and the packaging module.

[0013] Furthermore, the feeding mechanism includes a feeding wheel for placing consumables and a guide sheet metal. The processing component is located below the guide sheet metal, and the consumables pass through the guide sheet metal and bend to form a packaging bag shape. The processing component includes a bag clamping mechanism and a sealing and cutting mechanism, both of which include clamping blocks for sealing. The clamping blocks of the bag clamping mechanism are positioned to seal the side of the packaging bag along its length, and the clamping blocks of the sealing and cutting mechanism seal the ends of the packaging bag. The sealing and cutting mechanism also includes a cutting blade to cut the packaging bag after the ends are sealed.

[0014] Furthermore, the bag clamping mechanism includes a first driving cylinder, a left clamping block, and a right clamping block. The first driving cylinder drives the left and right clamping blocks to move relative to each other and move closer together. Both the left and right clamping blocks are made of thermally conductive materials, and each has a first clamping block space within it. A heating element is installed in the first clamping block space, and heat is conducted to the left and right clamping blocks through the heating element. The sealing and cutting mechanism includes a second driving cylinder, a front clamping block, and a rear clamping block. The second driving cylinder drives the front and rear clamping blocks to move closer together. Both the front and rear clamping blocks are made of thermally conductive materials, and each has a second clamping block space within it. A heating element is installed in the second clamping block space, and heat is conducted to the front and rear clamping blocks through the heating element.

[0015] Furthermore, a cutting groove is provided on the surfaces of the front clamping block and / or the rear clamping block facing each other; the sealing and cutting mechanism also includes a cutting cylinder connected to and controlling the extension and retraction of the cutting blade; the cutting blade is disposed in the cutting groove, and the cutting cylinder controls the cutting blade to protrude from the cutting groove to complete the cutting work.

[0016] Beneficial effects:

[0017] In this invention, the negative pressure generating component works in conjunction with the evaporator to create a negative pressure environment within the evaporation space. This negative pressure lowers the boiling point of the solution, thus achieving low-temperature evaporation. It avoids the problem of heat-sensitive components (such as proteins, enzymes, and volatile oils) being destroyed due to the high-temperature heating required by traditional atmospheric pressure evaporation, maximizing the retention of effective active substances (such as alkaloids and polysaccharides) in the medicinal solution, thereby improving the efficacy and quality of the product. Simultaneously, the negative pressure environment significantly shortens the time it takes for the solution to reach its boiling point, accelerates the water evaporation rate, and greatly improves overall production efficiency.

[0018] This equipment integrates concentration and filling functions, enabling immediate filling of concentrated medicine solutions, avoiding intermediate transfers and waiting times. This not only reduces the possibility of cross-contamination of medicine solutions and improves product quality and production efficiency, but also reduces material loss and space occupation.

[0019] Traditional concentration equipment often uses immersion heating, which can easily lead to excessively high local temperatures in the liquid, potentially damaging heat-sensitive components. In this invention, the heating space completely surrounds the evaporation space and is filled with a heat-conducting medium. Heating is uniformly conducted through this medium, preventing localized overheating of the liquid and eliminating localized temperature gradients, thus ensuring the liquid within the evaporation space is heated as evenly as possible.

[0020] Different medicinal solutions have different evaporation requirements; some require rapid evaporation of water, while others require slow concentration to retain volatile components. In this invention, the temperature can be increased by a heating device, or a suitable temperature liquid can be added by heating the liquid inlet, thereby adjusting the temperature of the liquid in the heating space to meet the evaporation requirements of different medicinal solutions. This enhances the adaptability of the equipment, enabling it to process a variety of medicinal solutions and meet different process requirements.

[0021] In this invention, the solenoid valve allows for the sealing of both the solution inlet and outlet, facilitating the extraction of gas from the evaporation space by the vacuum pump. This creates a negative pressure environment within the evaporation space, thereby lowering the boiling point of the solution. The vapor generated during evaporation can also be quickly extracted from the evaporation space by the vacuum pump, rapidly reducing moisture content and improving concentration efficiency. Under low temperature and negative pressure, the evaporation rate of moisture is accelerated, shortening the concentration process time and increasing production efficiency. Simultaneously, heat-sensitive components (such as alkaloids and polysaccharides) decompose less due to the lower evaporation temperature, resulting in more stable product efficacy.

[0022] In this invention, the condenser is connected and communicates with the evaporator and the water collection tank. A vacuum pump continuously draws in steam, causing it to quickly enter the condenser. This creates a stable negative pressure environment in the evaporation space, lowering the boiling point of the solution and accelerating evaporation. The steam generated from the evaporation of the solution may carry odors, microorganisms, or volatile organic compounds. The condenser condenses the steam into liquid, which is then collected into the water collection tank through a water collection connection pipe. This process collects both the steam and the condensate, preventing direct discharge that could pollute the production workshop.

[0023] During the negative pressure evaporation process, the liquid medicine may produce foam due to excessively low air pressure, caused by surface-active substances (such as proteins and polysaccharides). This foam typically contains unevaporated active ingredients from the liquid medicine. Excessive foam can be drawn out of the evaporation space by the vacuum pump, resulting in liquid medicine loss, reduced product yield, and increased raw material costs. In this invention, a foam sensor is used. When foam exceeds a threshold, the opening and closing of the vent valve can be finely adjusted to introduce atmospheric air at normal pressure, maintaining a stable negative pressure environment within the system and thus eliminating foam. Simultaneously, this vent valve is located at the water collection connection pipe, away from the evaporation space, thereby minimizing the impact of ambient air entering the evaporation space after the vent valve is opened on the internal temperature of the evaporation space.

[0024] In this invention, the operator can release the heat-conducting medium in the heating space by opening the drain valve, or fill the heating space with heat-conducting medium by opening the inlet valve. When the temperature of the heating medium in the heating space is too high, some high-temperature heating medium is released from the heating outlet, and then heating medium of appropriate temperature is added through the heating inlet, thereby achieving reasonable adjustment of the internal temperature of the heating space.

[0025] In this invention, the pressure that rises synchronously in the heating space due to the increase in temperature is released by setting a heating pressure relief port, thereby preventing the evaporator from being damaged by overpressure.

[0026] In traditional processes, the concentrated medicine solution needs to be manually transferred to the filling stage, which poses a risk of contamination. In this invention, the extraction and distribution module realizes the automated connection between the concentration and filling stages, reducing the possibility of medicine solution contamination and improving the quality of the medicine solution product.

[0027] In this invention, a final liquid measurement space is set inside the final liquid tank, and a final liquid measurement device is provided to monitor the volume or mass of the concentrated solution in real time; thereby avoiding underfilling or overfilling as much as possible, significantly reducing filling errors and improving the consistency of product dosage.

[0028] In this invention, the automatic forming of packaging bags is achieved through the cooperation of the feeding mechanism and processing components, and automatic filling is achieved through the concentration module and extraction and distribution module, thereby reducing the risk of drug contamination.

[0029] In this invention, the bag clamping mechanism and the sealing and cutting mechanism in the processing assembly work together: the bag clamping mechanism completes the side sealing of the packaging bag along its length (forming the side of the bag body), and the sealing and cutting mechanism then completes the end sealing (forming the end of the bag body) and immediately cuts and separates individual packaging bags by a cutting knife; this integrated process of "forming-side sealing-end sealing-cutting" is seamlessly connected, reducing intermediate transfer or waiting steps, significantly improving production efficiency, and realizing continuous automated production.

[0030] In this invention, the heating element is disposed in the space between the first and second clamping blocks, which not only protects the heating element through the clamping blocks, but also enables the heating element to stably conduct heat to each clamping block.

[0031] In this invention, the cutting blade is positioned within the cutting groove, and the cutting action is controlled by a cutting cylinder for extension and retraction. During the sealing stage, the front and rear clamping blocks close and tighten the end of the packaging bag. At this time, the cutting blade is hidden within the cutting groove to avoid interfering with the sealing. When cutting is required, the cutting cylinder drives the cutting blade to extend precisely from the cutting groove and directly cut the sealed end. When the heating element transfers heat to the front and rear clamping blocks, it can simultaneously transfer heat to the cutting blade, resulting in a better cutting effect. Attached Figure Description

[0032] Figure 1 This is a structural diagram of the entire utility model.

[0033] Figure 2 A structural diagram showing the inlet valve body and suction tube located on the inner surface of the housing.

[0034] Figure 3 This is a structural diagram of the valve body.

[0035] Figure 4 This is a cross-sectional view of the valve body.

[0036] Figure 5 This is a structural diagram of the present invention without a shell.

[0037] Figure 6 for Figure 5 The structural diagram of the other side.

[0038] Figure 7 This is a structural diagram of the condensation module.

[0039] Figure 8 This is a structural diagram of the evaporation assembly.

[0040] Figure 9 for Figure 8 Side view of the structure.

[0041] Figure 10 for Figure 8 Cross-sectional view.

[0042] Figure 11 This is a structural diagram of the interior of the evaporation space.

[0043] Figure 12 This is a structural diagram of a condenser.

[0044] Figure 13 for Figure 12 Cross-sectional view.

[0045] Figure 14 This is a structural diagram of the water collection tank.

[0046] Figure 15 for Figure 14 Cross-sectional view.

[0047] Figure 16 This is a structural diagram of the junction between the back-end branch pipeline and the inlet device.

[0048] Figure 17 The structure diagram for extracting the allocation module.

[0049] Figure 18 This is a cross-sectional view of the final liquid tank.

[0050] Figure 19 This is a cross-sectional view of the final liquid tank from another direction.

[0051] Figure 20 This is a structural diagram of the packaging module.

[0052] Figure 21 Structural diagram of the guide sheet metal.

[0053] Figure 22 This is a structural diagram of the bag clamping mechanism.

[0054] Figure 23 This is a structural diagram of the sealing and cutting mechanism.

[0055] Figure 24 This is a structural diagram of the cutting groove and cutting blade.

[0056] Numbering on the map:

[0057] 1. Concentration module; 2. Packaging module; 3. Evaporation assembly; 4. Heating device; 5. Negative pressure generating assembly; 6. Condensate tank; 7. Water collection tank; 8. Extraction and distribution module; 9. Inlet mechanism; 10. Cleaning module; 11. Water collection connection pipe; 12. Vent valve; 13. Drain valve; 14. Inlet valve; 15. Condensate connection pipe; 21. Feeding mechanism; 22. Bag clamping mechanism; 23. Sealing and cutting mechanism; 24. Conveying mechanism; 25. Packaging mounting plate; 26. Consumables; 31. Evaporation tank; 32. Foam sensor; 51. Vacuum pump; 61. Condensation space; 62. Partition plate; 63. Condensate pipe; 64. Condensate water inlet. 65. Condensate drain outlet; 71. Water collection space; 72. Drain interface; 73. Drain control valve; 74. Drain sensor; 81. Extraction pump; 82. Final liquid tank; 83. Distribution pump; 84. Final liquid measuring device; 91. Inlet valve body; 92. Rear branch pipe; 93. Inlet device; 101. Water supply device; 102. Rotary cleaning nozzle; 103. Housing; 104. Suction pipe; 211. Feeding wheel; 212. Guide sheet metal; 213. Guide inlet; 214. Guide outlet; 221. First drive cylinder; 222. Left clamping block; 223. Right clamping block; 224. First clamping block space; 231. Cutting blade; 232. Second drive cylinder; 233. Front clamping block; 234. Rear clamping block; 235. Second clamping block space; 236. Cutting groove; 237. Cutting cylinder; 311. Evaporation space; 312. Heating space; 313. Solution inlet; 314. Solution outlet; 315. Steam outlet; 316. Solution inlet; 317. Solution outlet pipe; 318. Heating inlet; 319. Heating outlet; 320. Heating pressure relief port; 321. Cleaning port; 611. First zone; 612. Second zone; 613. Third zone; 614. First condensation opening; 615. Second condensation opening; 711. Water collection inlet 712. Extraction connection port; 713. Drain outlet; 821. Final liquid measurement space; 822. Concentrate inlet; 823. Concentrate outlet; 824. Concentrate inlet valve; 825. Concentrate outlet valve; 826. Final liquid tank cleaning port; 827. Final liquid tank cleaning valve; 828. Final liquid tank drain outlet; 829. Liquid tank drain valve; 911. Solution inlet channel; 912. Cleaning fluid inlet channel; 913. Liquid outlet channel; 914. Solution inlet opening; 915. Cleaning inlet opening; 916. Liquid outlet; 917. Valve switch; 921. Inlet pipe; 922. First distributor pipe; 923. Second distributor pipe. Detailed Implementation

[0058] The present invention will be further described below with reference to the accompanying drawings and specific embodiments. It should be noted that the embodiments are merely specific descriptions of the present invention, and their purpose is to enable those skilled in the art to better understand the technical solution of the present invention, and should not be regarded as limitations on the present invention.

[0059] In the description of this utility model, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0060] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0061] Example:

[0062] like Figure 1-24 As shown, a solution concentration and filling device includes a concentration module 1 and a packaging module 2. The concentration module 1 includes an evaporation component 3 with an evaporator 31, a heating device 4 that provides heat to the evaporator 31, and a negative pressure generating component 5. The evaporator 31 is provided with an evaporation space 311 for solution evaporation and concentration. The negative pressure generating component 5 cooperates with the evaporator 31 to form a negative pressure in the evaporation space 311. The packaging module 2 includes a feeding mechanism 21 for providing consumables 26 and a processing component for making the consumables 26 into packaging bags. The evaporator 31 cooperates with the packaging module 2 to transport the concentrated solution into the packaging bag made by the processing component.

[0063] In this invention, the negative pressure generating component 5 works in conjunction with the evaporator 31 to create a negative pressure environment within the evaporation space 311. The negative pressure lowers the boiling point of the solution, thus achieving low-temperature evaporation. This avoids the problem of heat-sensitive components (such as proteins, enzymes, and volatile oils) being destroyed due to the high-temperature heating required by traditional atmospheric pressure evaporation, maximizing the retention of effective active substances (such as alkaloids and polysaccharides) in the medicinal solution, thereby improving the efficacy and quality of the product. Simultaneously, the negative pressure environment significantly shortens the time required for the solution to reach its boiling point, accelerates the water evaporation rate, and greatly improves overall production efficiency.

[0064] This equipment integrates concentration and filling functions, enabling immediate filling of concentrated medicine solutions, avoiding intermediate transfers and waiting times. This not only reduces the possibility of cross-contamination of medicine solutions and improves product quality and production efficiency, but also reduces material loss and space occupation.

[0065] In this invention, a heating space 312 is also provided inside the evaporator 31; the heating space 312 and the evaporation space 311 are relatively sealed; the heating space 312 surrounds the evaporation space 311 and is filled with a heat-conducting medium; the heating device 4 is located inside the heating space 312 to control the temperature of the heat-conducting medium. Traditional concentration equipment often uses immersion heating, which can easily lead to excessively high local temperatures in the liquid, potentially damaging heat-sensitive components in the liquid; in this invention, the heating space 312 completely surrounds the evaporation space 311 and is filled with a heat-conducting medium; the heat is uniformly conducted through the heat-conducting medium, avoiding local overheating of the liquid, thereby eliminating local temperature gradients and ensuring that the liquid in the evaporation space 311 is heated as evenly as possible.

[0066] In this invention, the evaporator 31 is provided with a solution inlet 313, a solution outlet 314, and a steam outlet 315 communicating with the evaporation space 311; the negative pressure generating component 5 includes a vacuum pump 51, which cooperates with the steam outlet 315 to extract gas in the evaporation space 311 to form a negative pressure environment in the evaporation space 311; a solution inlet 316 is provided at the solution inlet 313, and a solution outlet 317 is provided at the solution outlet 314, which passes through the heating space 312 and protrudes from the evaporator 31; both the solution inlet 316 and the solution outlet 317 are provided with solenoid valves to control their conduction state. By using solenoid valves, the solution inlet 313 and solution outlet 314 can be sealed, which facilitates the extraction of gas from the evaporation space 311 by the vacuum pump 51, creating a negative pressure environment in the evaporation space 311. This lowers the boiling point of the solution in the evaporation space 311. The vapor generated during evaporation can also be quickly extracted from the evaporation space 311 by the vacuum pump 51, rapidly reducing the moisture content and improving concentration efficiency. Under low temperature and negative pressure, the moisture evaporation rate is accelerated, shortening the concentration process time and improving production efficiency. At the same time, heat-sensitive components (such as alkaloids and polysaccharides) decompose less due to the lower evaporation temperature, resulting in more stable product efficacy.

[0067] Different medicinal solutions have different evaporation requirements; some require rapid evaporation of water, while others require slow concentration to retain volatile components. In this invention, the temperature can be increased by the heating device 4, or a suitable temperature liquid can be added by the heating inlet 318, thereby adjusting the temperature of the liquid in the heating space 312 to meet the evaporation requirements of different medicinal solutions. This enhances the adaptability of the equipment, enabling it to process a variety of medicinal solutions and meet different process requirements.

[0068] In this invention, the concentration module 1 further includes a condenser tank 6 and a water collection tank 7. The condenser tank 6 is connected to and communicates with the evaporator tank 31 and the water collection tank 7. A vacuum pump 51 is connected to and cooperates with the water collection tank 7 to draw the steam generated by the evaporation component 3 into the condenser tank 6, and then draws the condensate formed by the steam in the condenser tank 6 into the water collection tank 7. This creates a stable negative pressure environment in the evaporation space 311, lowering the boiling point of the solution and accelerating evaporation. The condenser tank 6 is connected to and communicates with the evaporator tank 31 and the water collection tank 7. The vacuum pump 51 continuously draws in steam, allowing it to quickly enter the condenser tank 6. The steam formed by the evaporation of the solution may carry odors, microorganisms, or volatile organic compounds. The condenser tank 6 condenses the steam into liquid and collects it into the water collection tank 7. This process collects the steam and condensate, preventing direct discharge that could pollute the production workshop.

[0069] In this invention, a foam sensor 32 is installed on the evaporator 31, and the sensing part of the foam sensor 32 is located inside the evaporation space 311. The condenser 6 and the water collection tank 7 are connected by a water collection connecting pipe 11, and a vent valve 12 for introducing atmospheric pressure air is also installed at the water collection connecting pipe 11. During the negative pressure evaporation process, the liquid medicine may produce foam due to the low air pressure caused by surface active substances (such as proteins and polysaccharides). The foam usually contains unevaporated effective components of the liquid medicine. When there is too much foam, it will be sucked out of the evaporation space 311 when the vacuum pump 51 is working, resulting in liquid medicine loss, reduced product yield, and increased raw material costs. In this invention, by setting up the foam sensor 32, when foam is detected to exceed the threshold, the opening and closing state of the vent valve 12 can be finely adjusted to introduce atmospheric air at normal pressure, maintain a stable negative pressure environment in the system, and thus eliminate the foam. At the same time, the vent valve 12 is set at the water collection connection pipe 11, in a position far away from the evaporation space 311, thereby minimizing the impact of the opening of the vent valve 12 and the entry of ambient air on the internal temperature of the evaporation space 311.

[0070] In this invention, the evaporator 31 is provided with a heating inlet 318 and a heating outlet 319 communicating with the heating space 312 for charging and discharging the heat-conducting medium. A water inlet valve 14 and a water outlet valve 13 are also provided at both inlet and outlet. Operators can release the heat-conducting medium from the heating space 312 by opening the water outlet valve 13, or charge the heating space 312 with the heat-conducting medium by opening the water inlet valve 14. When the temperature of the heating medium in the heating space 312 is too high, some high-temperature heating medium is released from the heating outlet 319, and then heating medium at a suitable temperature is replenished through the heating inlet 318, thereby achieving reasonable temperature regulation inside the heating space 312.

[0071] In this utility model, the evaporator 31 is also provided with a heating pressure relief port 320 that communicates with the heating space 312. By providing the heating pressure relief port 320, the pressure in the heating space 312 that increases synchronously due to the temperature rise is released, thereby preventing the evaporator 31 from being damaged by overpressure.

[0072] In this embodiment, the vacuum pump 51 is a water-circulating vacuum pump 51. Since the vacuum pump 51 needs to draw in steam, and the condenser 6 cannot guarantee that all the steam will be condensed into condensate, the non-water-circulating vacuum pump 51 may be damaged after drawing in steam; while the water-circulating vacuum pump 51 is less likely to cause this problem.

[0073] In this invention, an extraction and distribution module 8 is provided between the concentration module 1 and the packaging module 2. This module includes an extraction pump 81, a final liquid tank 82, and a distribution pump 83. The final liquid tank 82 contains a final liquid measurement space 821, and a final liquid measurement device 84 for measuring solution volume is installed on the final liquid tank 82. The final liquid tank 82 has a concentration inlet 822 and a concentration outlet 823 communicating with the final liquid measurement space 821, and a concentration inlet valve 824 and a concentration outlet valve 825 are respectively installed at both outlets. The extraction pump 81 cooperates with the concentration inlet valve 824 and the solution outlet pipe 317. The distribution pump 83 cooperates with the concentration outlet valve 825 and the packaging module 2. In traditional processes, the concentrated drug solution needs to be manually transferred to the filling stage, posing a risk of contamination. In this invention, the extraction and distribution module 8 achieves automated connection between the concentration and filling stages, reducing the possibility of drug solution contamination and improving the quality of the drug solution product.

[0074] In this embodiment, the final liquid measurement space 821 of the final liquid tank 82 is vertically arranged, and the shape and inner diameter of the final liquid measurement space 821 are consistent in the vertical direction. This ensures that the final concentrate is evenly distributed in the vertical final liquid measurement space 821, and the liquid level height has a strict linear relationship with the volume; thus, the accuracy of the final liquid volume measurement data is significantly improved. The length direction of the sensing part of the final liquid measurement device 84 corresponds to the length direction of the final liquid measurement space 821, thereby enabling it to more accurately measure the volume of the final concentrate.

[0075] This invention includes an inlet mechanism 9, which comprises an inlet valve body 91, an inlet pipe, and an inlet device 93. The inlet pipe cooperates with the inlet valve body 91 and the solution inlet interface 316, and the inlet device 93 cooperates with the inlet pipe to draw the solution from the inlet valve body 91 and guide it to the evaporation space 311. In traditional equipment, the solution needs to be manually poured into the evaporator 31, which is time-consuming and prone to human error, such as inaccurate pouring or solution leakage, affecting the concentration effect. In this invention, through the setting and cooperation of the inlet valve body 91, the inlet pipe, and the inlet device 93, the solution to be concentrated is automatically sent into the evaporator 31 for concentration. This avoids solution overflow or insufficient quantity caused by manual operation, thereby ensuring the efficiency and quality of concentration.

[0076] In this invention, the solenoid valve controlling the conduction state of the solution inlet 316 is located at the inlet pipe. Since the solution inlet 316 needs to be connected to the inlet pipe, a certain amount of space is required for the connection operation. If the solenoid valve is installed at the solution inlet 316, it may affect the connection operation between the solution inlet 316 and the inlet pipe. The connection effect directly affects whether the concentrated drug solution can flow completely into the evaporation space 311. If the connection is not tight, the concentrated drug solution may leak, resulting in loss of potency and affecting the final product. However, after the solution inlet 316 is connected to the inlet pipe, controlling the conduction state of the inlet pipe is equivalent to controlling the conduction state of the solution inlet 316. Therefore, placing the solenoid valve at the inlet pipe minimizes interference and facilitates operation.

[0077] This utility model also includes a cleaning module 10, which includes a water supply device 101. The water supply device 101 cooperates with the final liquid tank 82 and the inlet valve body 91, and provides cleaning water to the inlet valve body 91 and the final liquid measurement space 821. This enables the cleaning of the final liquid measurement space 821, the pipeline from the inlet valve body 91 to the evaporation space 311, the evaporation space 311, and the pipeline from the evaporation space 311 to the final liquid measurement space 821. When the equipment switches to the type of concentrated medicine, it can also avoid mixing of different medicines, which would affect the output.

[0078] In this embodiment, the water supply device 101 is a water heater, which provides hot water for operation; compared with cold water, using hot water for equipment cleaning can achieve better cleaning results.

[0079] In this embodiment, the final liquid tank 82 is provided with a final liquid tank cleaning port 826 communicating with the final liquid measurement space 821, and a final liquid tank cleaning valve 827 is provided at the final liquid tank cleaning port 826. The water supply device 101 cooperates with the final liquid tank cleaning valve 827 to supply water. The final liquid tank cleaning port 826 is located near the top of the final liquid measurement space 821 to facilitate cleaning. The final liquid tank 82 is also provided with a final liquid tank drain port 828 communicating with the final liquid measurement space 821. The final liquid tank drain port 828 is located near the bottom of the final liquid measurement space 821, and the concentrated liquid outlet 823 is located at the lowest point of the final liquid measurement space 821. The height of the final liquid tank drain port 828 is higher than the height of the concentrated liquid outlet 823. A final liquid tank drain valve is provided at the final liquid tank drain port 828. This equipment uses the cooperation of the final liquid tank cleaning port 826 and the final liquid tank drain port 828 to complete the cleaning work by allowing water to enter and exit the final liquid tank 82. At the same time, since the final liquid tank drain port 828 is located at a higher position than the concentrated liquid outlet 823, the remaining cleaning water can be discharged through the concentrated liquid outlet 823, thereby cleaning the pipeline from the final liquid tank 82 to the packaging module 2.

[0080] In this embodiment, the inlet valve body 91 is a three-way valve, internally equipped with a solution inlet channel 911, a cleaning fluid inlet channel 912, and a liquid outlet channel 913, and correspondingly equipped with a solution inlet opening 914, a cleaning fluid inlet opening 915, and a liquid outlet 916; the water supply device 101 is connected to the cleaning fluid inlet opening 915; the liquid outlet 916 is connected to the inlet pipeline; the inlet valve body 91 is equipped with a valve switch 917 to control the opening and closing of the solution inlet channel 911, the cleaning fluid inlet channel 912, and the liquid outlet channel 913. The inlet valve body 91 uses a three-way valve, allowing the cleaning fluid from the water supply device 101 to clean all paths of the liquid flow as needed, thus avoiding mixing of different liquids.

[0081] In this embodiment, the inlet pipeline includes a front-end pipeline and a rear-end branch pipeline 92, and the inlet device 93 adopts a self-priming pump. The front-end pipeline is connected to the liquid outlet 916 and the suction port of the self-priming pump, and the two are in communication. The rear-end branch pipeline 92 includes an inlet pipe 921, a first branch pipe 922 and a second branch pipe 923. The inlet pipe 921 is in communication with the first branch pipe 922 and the second branch pipe 923 respectively. The inlet pipe 921 is connected to and in communication with the discharge port of the self-priming pump, and the first branch pipe 922 is in cooperation with and in communication with the solution inlet interface 316.

[0082] In this embodiment, the solenoid valve controlling the conduction state of the solution addition interface 316 is set on the first dispensing pipe 922, thereby providing convenience for the connection and cooperation between the first dispensing pipe 922 and the solution addition interface 316 without affecting the original function, and also making it easier to improve the tightness of the connection and cooperation between the two.

[0083] In this embodiment, the cleaning module 10 further includes a rotating cleaning nozzle 102 located within the evaporation space 311. The evaporation tank 31 is equipped with a cleaning interface 321 that connects and cooperates with the rotating cleaning nozzle 102. A second dispensing pipe 923 cooperates with and communicates with the cleaning interface 321. A solenoid valve controlling the conduction state is installed on the second dispensing pipe 923. During solution introduction and initial cleaning, the solenoid valve on the second dispensing pipe 923 is closed, and only the solenoid valve on the first dispensing pipe 922 is opened to ensure that the solution can be introduced into the evaporation space 311 and that the path through which the solution flows can be cleaned. During further cleaning, the second dispensing pipe 923 is opened again to supply water to the rotating cleaning nozzle 102, which then performs the cleaning. This makes the cleaning work of this equipment more precise and of higher quality.

[0084] In this embodiment, a housing 103 is also included, which surrounds the other modules. The inlet valve body 91 is fixed to the inner surface of the housing 103, and the valve switch 917 of the inlet valve body 91 is located outside the housing 103, thus facilitating operator control of the valve switch 917. A suction tube 104 is also fixedly installed on the housing 103. One end of the suction tube 104 is inside the housing 103 and is connected to the solution inlet opening 914 of the inlet valve body 91 through a pipeline. The other end of the suction tube 104 is outside the housing 103, allowing the operator to connect a pipeline at this end to assist in drawing in the concentrated drug solution with a self-priming pump.

[0085] In this invention, a condenser tank 6 has a condensation space 61 inside; a partition 62 is provided in the condensation space 61, dividing it into a first region 611, a second region 612, and a third region 613; the first region 611 and the third region 613 are located at both ends of the condenser tank 6, and the second region 612 is located between the two, with each space being relatively sealed; a first condensation opening 614 communicating with the first region 611 and a second condensation opening 615 communicating with the third region 613 are respectively provided at both ends of the condenser tank 6; the first condensation opening 614 is connected to and communicates with the evaporator tank 31, and the second condensation opening 615 is connected to and communicates with the water collection tank 7; the first condensation opening 614 is connected to the steam outlet 315 through a condensation connecting pipe 15, so that the first region 611 communicates with the evaporation space 311. A condenser pipe 63 is installed in the second region 612. Both ends of the condenser pipe 63 have openings that connect it to the first region 611 and the third region 613, and also connect the first region 611 and the third region 613. The condenser pipe 63 is relatively sealed to the second condensation space 61. The condenser tank 6 is also equipped with a condensate inlet 64 and a condensate drain outlet 65 that communicate with the second region 612. The interior of the condenser tank 6 is divided into the first region 611, the second region 612, and the third region 613 by a partition 62, thus forming a directional path for steam flow. When steam passes through the condenser pipe 63, it can fully exchange heat with the condensing medium in the second region 612, and then condense to form condensate water which finally enters the water collection tank 7. In this embodiment, the condensate inlet 64 is located at the bottom of the condenser tank 6, and the condensate drain outlet 65 is located at the top of the condenser tank 6. This ensures that when the device injects condensing medium into the second region 612, the second space is completely filled before overflowing, thereby allowing the steam in the condenser tube 63 to achieve a better heat exchange effect. Generally, water is used as the condensing medium in the second space. Simultaneously, since hot water has a lower density than cold water, the water surrounding the condenser tube 63 in the second region 612 will heat up after heat exchange with the steam in the condenser tube 63, gradually rising to the surface of the cold water. The condensate drain outlet 65 at the top of the condenser tank 6 allows the warmer water to overflow more effectively, maintaining a suitable liquid temperature in the second space to achieve a better condensation effect.

[0086] In this invention, a water collection tank 7 is positioned below a condenser tank 6. The water collection tank 7 contains a water collection space 71, and is equipped with a water collection inlet 711, an extraction connection port 712, and a drain outlet 713, all communicating with the water collection space 71. The water collection inlet 711 and the extraction connection port 712 are located at the top of the water collection tank 7, with the extraction connection port 712 connected to a vacuum pump 51. This prevents the vacuum pump 51 from directly drawing condensate from the water collection space 71, thus avoiding the formation of negative pressure. The drain outlet 713 is located at the bottom of the water collection tank 7 and at the lowest point of the water collection space 71. A drain interface 72 is provided at the drain outlet 713, and a drain control valve 73 and a drain sensor 74 are installed at the drain interface 72 to detect whether there is water in the drain interface 72 and the water collection space 71. The water collection inlet 711 is connected to a second condensation opening 615 via a water collection connecting pipe 11, allowing the water collection space 71 to communicate with the third region 613.

[0087] In this invention, the feeding mechanism 21 includes a feeding wheel 211 for placing consumable 26 and a guide sheet metal 212. A processing component is positioned below the guide sheet metal 212. The consumable 26 passes through the guide sheet metal 212 and bends to form a packaging bag shape. The processing component includes a bag clamping mechanism 22 and a sealing and cutting mechanism 23, both of which include clamping blocks for sealing. The clamping blocks of the bag clamping mechanism 22 are positioned along the length of the packaging bag to perform side sealing, while the clamping blocks of the sealing and cutting mechanism 23 seal the ends of the packaging bag. The sealing and cutting mechanism 23 also includes a cutting blade 231 to cut the sealed packaging bag. The automatic forming of the packaging bag is achieved through the cooperation of the feeding mechanism 21 and the processing component. Combined with the concentration module 1 and the extraction and dispensing module 8, automatic filling is achieved, thereby reducing the risk of drug contamination.

[0088] In this invention, the bag clamping mechanism 22 and the sealing and cutting mechanism 23 in the processing components work together: the bag clamping mechanism 22 completes the side sealing of the packaging bag along its length (forming the side of the bag body), and the sealing and cutting mechanism 23 then completes the end sealing (forming the end of the bag body) and immediately cuts and separates individual packaging bags by the cutting blade 231; this integrated process of "forming-side sealing-end sealing-cutting" is seamlessly connected, reducing intermediate transfer or waiting steps, significantly improving production efficiency, and realizing continuous automated production.

[0089] In this utility model, the bag clamping mechanism 22 includes a first driving cylinder 221, a left clamping block 222, and a right clamping block 223. The first driving cylinder 221 drives the left clamping block 222 and the right clamping block 223 to move relative to each other and move closer together. The left clamping block 222 and the right clamping block 223 are both made of thermally conductive materials, and each of them is provided with a first clamping space 224. A heating element is provided in the first clamping space 224, and heat is conducted to the left clamping block 222 and the right clamping block 223 through the heating element. The sealing and cutting mechanism 23 includes a second driving cylinder 232 and a front clamping... The front clamping block 233 and the rear clamping block 234 are driven by the second driving cylinder 232 to move closer to each other; both the front clamping block 233 and the rear clamping block 234 are made of thermally conductive materials, and both are provided with a second clamping block space 235; a heating element is provided in the second clamping block space 235, and heat is conducted to the front clamping block 233 and the rear clamping block 234 through the heating element; the heating element is set in the first and second clamping block spaces 235, which not only protects the heating element through the clamps, but also enables the heating element to stably conduct heat to each clamping block.

[0090] In this invention, a cutting groove 236 is provided on the surfaces of the front clamping block 233 and / or the rear clamping block 234 facing each other; the sealing and cutting mechanism 23 also includes a cutting cylinder 237 connected to and controlling the extension and retraction of the cutting blade 231; the cutting blade 231 is disposed in the cutting groove 236, and the cutting cylinder 237 controls the cutting blade 231 to protrude from the cutting groove 236 to complete the cutting work. During the sealing stage, the front and rear clamping blocks 234 close and clamp the end of the packaging bag, at which time the cutting blade 231 is hidden in the cutting groove 236 to avoid interfering with the sealing; when cutting is required, the cutting cylinder 237 drives the cutting blade 231 to extend precisely from the cutting groove 236 and directly cut the sealed end. When the heating element transfers heat to the front and rear clamping blocks 234, it can simultaneously transfer heat to the cutting blade 231, making the cutting effect of the cutting blade 231 better.

[0091] In this invention, the packaging module 2 further includes a conveying mechanism 24 disposed between the bag clamping mechanism 22 and the sealing and cutting mechanism 23. The consumable material 26 passes through the guide sheet metal 212 and is bent to form a packaging bag shape. The bag clamping mechanism 22 seals the consumable material 26 along its length, initially forming the packaging bag shape. The conveying mechanism 24 transports the side-sealed packaging bag to the sealing and cutting mechanism 23, where the bottom of the packaging bag is sealed and cut. Subsequently, after the dispensing pump 83 injects concentrated medicine into the packaging bag through the unsealed top, the conveying mechanism 24 continues to convey the bag, and the sealing and cutting mechanism 23 completes the top sealing and cutting of the packaging bag, thus completing the filling of the formulation. In traditional packaging processes, sealing, filling, and cutting are usually separate operations, requiring manual intervention or waiting for the previous step to complete. This design uses the conveying mechanism 24 to connect the various steps into a continuous process, thereby improving production efficiency. Meanwhile, during operation, the sealing and cutting mechanism 23 not only completes the top sealing of the previous bag of preparation but also the bottom sealing of the next bag of preparation, thereby improving filling efficiency.

[0092] In this embodiment, the upper and lower ends of the guide sheet metal 212 are respectively provided with guide inlet 213 and guide outlet 214; the guide inlet 213 of the guide sheet metal 212 is larger than the guide outlet 214, and the guide outlet 214 is annular, which is beneficial for the consumable 26 to bend and form a packaging bag shape after passing through the guide sheet metal 212 for subsequent side sealing.

[0093] In this embodiment, cutting grooves 236 are provided on the surfaces of the front clamping block 233 and the rear clamping block 234 facing each other, and the cutting blade 231 is disposed in the cutting groove 236 of the rear clamping block 234. When the front clamping block 233 and the rear clamping block 234 seal the packaging bag, the sealed part of the packaging bag is located at the opening of the cutting groove 236 of the front and rear clamping blocks 234, thereby giving the cutting blade 231 more room to move and making it less likely to be damaged.

[0094] It is worth noting that, in this utility model, the opening of the solenoid valve, the inlet valve body 91, the final liquid tank cleaning valve 827, the concentrate outlet valve 825, and other valve bodies refers to opening the valve body so that it or its set position is in a conductive state, enabling liquid flow; similarly, the closing of the above valve bodies refers to closing the valve body so that it or its set position is in a closed state.

[0095] It is worth noting that the other technical solutions of this utility model are all existing technologies, and therefore will not be described in detail.

[0096] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the concept of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.

Claims

1. A solution concentration and filling device, characterized in that, Includes a concentration module and a packaging module; The concentration module includes an evaporation assembly with an evaporator, a heating device that supplies heat to the evaporator, and a negative pressure generating assembly; the evaporator is provided with an evaporation space for evaporating and concentrating the solution, and the negative pressure generating assembly works with the evaporator to form a negative pressure in the evaporation space; The packaging module includes a feeding mechanism for providing consumables and a processing component for turning the consumables into packaging bags; The evaporator works in conjunction with the packaging module to deliver the concentrated solution into a packaging bag made from the processing components.

2. The solution concentration and filling equipment according to claim 1, characterized in that, The evaporator also has a heating space; the heating space and the evaporation space are relatively sealed; the heating space surrounds the evaporation space and is filled with a heat-conducting medium; a heating device is installed in the heating space to control the temperature of the heat-conducting medium.

3. The solution concentration and filling equipment according to claim 2, characterized in that, The evaporator is equipped with a solution inlet, a solution outlet, and a steam outlet that communicate with the evaporation space. The negative pressure generating component includes a vacuum pump, which works in conjunction with the steam outlet to extract gas from the evaporation space and create a negative pressure environment within the evaporation space. A solution inlet is provided at the solution inlet, and a solution outlet is provided at the solution outlet, which passes through the heating space and protrudes from the evaporator. Solenoid valves that control the conduction state of both the solution inlet and the solution outlet are provided at both the solution inlet and the solution outlet.

4. The solution concentration and filling equipment according to claim 3, characterized in that, The concentration module also includes a condenser and a water collection tank; the condenser is connected to and communicates with the evaporator and the water collection tank; the vacuum pump is connected to the water collection tank to draw the steam generated by the evaporation component into the condenser, and then draw the condensate formed by the steam in the condenser into the water collection tank.

5. The solution concentration and filling equipment according to claim 4, characterized in that, A foam sensor is installed on the evaporator, and the sensing part of the foam sensor is located inside the evaporation space; The condenser and the water collection tank are connected by a water collection connection pipe, and a vent valve that allows atmospheric pressure air to enter is also installed at the water collection connection pipe.

6. The solution concentration and filling equipment according to claim 2, characterized in that, The evaporator is equipped with a heating inlet and a heating outlet that communicate with the heating space for filling and discharging the heat transfer medium, and a water inlet valve and a water outlet valve are installed at both of them; The evaporator is also equipped with a heating pressure relief port that communicates with the heating space.

7. The solution concentration and filling equipment according to claim 3, characterized in that, An extraction and distribution module is also provided between the concentration module and the packaging module, which includes an extraction pump, a final liquid tank, and a distribution pump. The final liquid tank is equipped with a final liquid measurement space and a final liquid measurement device for measuring the solution volume. The final liquid tank is equipped with a concentration inlet and a concentration outlet that communicate with the final liquid measurement space, and a concentration inlet valve and a concentration outlet valve are respectively provided at both. The extraction pump works in conjunction with the concentration inlet valve and the solution outlet pipe. The distribution pump works in conjunction with the concentration outlet valve and the packaging module.

8. The solution concentration and filling equipment according to claim 7, characterized in that, The feeding mechanism includes a feeding wheel for placing consumables and a guide sheet metal. The processing component is located below the guide sheet metal. The consumables pass through the guide sheet metal and bend to form the shape of a packaging bag. The processing component includes a bag clamping mechanism and a sealing and cutting mechanism. Both of them include clamping blocks for sealing. The clamping blocks of the bag clamping mechanism are set to seal the side of the packaging bag along its length. The clamping blocks of the sealing and cutting mechanism seal the ends of the packaging bag. The sealing and cutting mechanism also includes a cutting blade to cut the packaging bag after the ends are sealed.

9. A solution concentration and filling device according to claim 8, characterized in that, The bag clamping mechanism includes a first drive cylinder, a left clamping block, and a right clamping block. The first drive cylinder drives the left clamping block and the right clamping block to move relative to each other and move closer to each other. The left clamping block and the right clamping block are both made of thermally conductive materials, and each of them is provided with a first clamping block space. A heating element is provided in the first clamping block space, and heat is conducted to the left clamping block and the right clamping block through the heating element. The sealing and cutting mechanism includes a second drive cylinder, a front clamping block, and a rear clamping block. The second drive cylinder drives the front clamping block and the rear clamping block to move closer to each other. Both the front clamping block and the rear clamping block are made of thermally conductive materials, and each of them has a second clamping block space. A heating element is set in the second clamping block space, and heat is conducted to the front clamping block and the rear clamping block through the heating element.

10. A solution concentration and filling device according to claim 9, characterized in that, A cutting groove is provided on the surfaces of the front clamping block and / or the rear clamping block facing each other; the sealing and cutting mechanism also includes a cutting cylinder connected to and controlling the extension and retraction of the cutting blade; the cutting blade is disposed in the cutting groove, and the cutting cylinder controls the cutting blade to protrude from the cutting groove to complete the cutting work.

Images