A hand-operated wet granulator for pharmaceutical production

Abstract

The utility model discloses a hand -operated wet granulator for medicine production, including making workstation, the making workstation is installed with the pressure wheel shell, the pressure wheel shell is in the bearing swing installation with the pressure wheel structure, the lower surface of making workstation is located the lower end port of pressure wheel shell fixed mounting has the granulation outer frame, the inboard fixed mounting of granulation outer frame has the granulation net. The utility model discloses a hand -operated wet granulator for medicine production, can be through the rotation of rubbing grain convex and be extruded to the medicament group in the pressure wheel shell of input, and the medicament group of being extruded becomes the strip of mesh -sized through the mesh cutting of granulation net mesh, but because its tackiness is poor, and the strip is very easy to break into granules under the condition of vibration and processing shake, to complete the making, and the granulator whole structure is simple, is driven through manual, and simple and easy energy -conserving and swift, and simple structure makes the low production cost, is more suitable for laboratory demand use.

Description

Technical Field

[0001] This utility model relates to the field of granule drug development and processing technology, and in particular to a hand-cranked wet granulation machine for pharmaceutical production. Background Technology

[0002] Currently, most pharmaceutical granules produced in the laboratory are made by hand-rolling or by using a granulator. Hand-rolling is not only inefficient but also time-consuming and labor-intensive, and is mostly used in laboratories. Granulators, on the other hand, are large in structure and suitable for production needs, but not for experimental needs, and are expensive to purchase. Therefore, we propose a hand-cranked wet granulator for pharmaceutical production. Utility Model Content

[0003] The main objective of this invention is to provide a hand-cranked wet granulation machine for pharmaceutical production, which can effectively solve the problems in the background art.

[0004] To achieve the above objectives, the technical solution adopted by this utility model is as follows: A hand-cranked wet granulation machine for pharmaceutical production includes a production workbench, on which a pressure roller housing is mounted. A pressure roller structure is movably mounted inside the pressure roller housing via bearings. A granulation frame is fixedly mounted on the lower surface of the production workbench at the lower end of the pressure roller housing. A granulation screen is fixedly mounted on the inner side of the granulation frame. A receiving platform is fixedly mounted on the inner side of the production workbench below the granulation frame.

[0005] Preferably, the arc surface of the pressure roller housing is provided with a feeding port.

[0006] Preferably, the pressure roller structure includes a rotating shaft movably mounted on the pressure roller housing via a bearing, a rotating roller fixedly sleeved on the outer surface of the rotating shaft, a crank handle connected to one end of the rotating shaft, and a granulation protrusion fixed to the outer arc surface of the rotating roller.

[0007] Preferably, there are six granulation protrusions, which are evenly distributed on the outer arc surface of the central rotating wheel, and one side of each granulation protrusion is a rounded arc surface.

[0008] Preferably, when the pelletizing protrusion is rotated to its lowest position, the distance between it and the top of the pelletizing screen is 1mm to 4mm.

[0009] Compared with the prior art, the present invention has the following beneficial effects: In this invention, a hand-cranked wet granulation machine for pharmaceutical production can compress a granulation mass fed into the pressure roller housing by rotating granulation protrusions. The compressed granulation mass is cut into strips of the same size as the mesh through the granulation screen. However, due to its poor viscosity, the strips are easily broken into granules under vibration and processing shaking, thus completing the production process. The granulation machine has a simple overall structure, is manually driven, and is easy, energy-saving, and quick to operate. Its simple structure also results in low production costs, making it more suitable for laboratory use. Attached Figure Description

[0010] Figure 1 This is a schematic diagram of the overall structure of a hand-cranked wet granulation machine for pharmaceutical production according to this utility model; Figure 2 This is a partial cross-sectional view of a hand-cranked wet granulation machine for pharmaceutical production according to this utility model; Figure 3 This is a diagram illustrating the granulation frame and granulation screen of a hand-cranked wet granulation machine for pharmaceutical production according to this utility model.

[0011] In the diagram: 1. Production workbench; 2. Press roller housing; 21. Feeding port; 3. Press roller structure; 31. Central rotating roller; 32. Pelletizing protrusion; 33. Central rotating shaft; 34. Handle; 4. Pelletizing frame; 5. Pelletizing screen; 6. Receiving platform; 7. Bearing. Detailed Implementation

[0012] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments. Example

[0013] like Figure 1-3 As shown, a hand-cranked wet granulation machine for pharmaceutical production includes a production workbench 1, a pressure roller housing 2 installed on the production workbench 1, a pressure roller structure 3 movably installed inside the pressure roller housing 2 via a bearing 7, a granulation frame 4 fixedly installed on the lower surface of the production workbench 1 at the lower port of the pressure roller housing 2, a granulation screen 5 fixedly installed on the inner side of the granulation frame 4, and a receiving platform 6 fixedly installed on the inner side of the production workbench 1 below the granulation frame 4. The arc surface of the pressure roller housing 2 is provided with a feeding port 21; Specifically, the feeding port 21 is used to feed the material for making pharmaceutical granules into the pressure roller shell 2.

[0014] The pressure roller structure 3 includes a central rotating shaft 33 movably mounted on the pressure roller housing 2 via a bearing 7, a central rotating wheel 31 fixedly sleeved on the outer surface of the central rotating shaft 33, a crank handle 34 connected to one end of the central rotating shaft 33, and a granulation protrusion 32 fixed on the outer arc surface of the central rotating wheel 31. Specifically, after the pharmaceutical material is kneaded into a ball and put into the pressure roller housing 2, the central rotating shaft 33 is rotated by turning the crank handle 34, which in turn drives the central rotating roller 31 to rotate. In this way, the granulation protrusions 32 on the central rotating roller 31 will squeeze the material into a ball on the granulation mesh 5 in the granulation frame 4 through their raised rounded arc surfaces and their flat surfaces. The squeezed material will be made into strips through the mesh of the granulation mesh 5. However, due to the poor viscosity of the pharmaceutical material, the squeezed strips will break after reaching a certain length, thus forming granules that fall onto the receiving platform 6 for collection.

[0015] There are six tufting protrusions 32, which are evenly distributed on the outer arc surface of the central rotating wheel 31. One side of the tufting protrusions 32 is a rounded arc surface. Specifically, the multiple granulation protrusions 32 enable the pharmaceutical material to be extruded and granulated at high frequency during rotation, thereby enabling more efficient granulation production and improving work efficiency.

[0016] When the pelletizing protrusion 32 is rotated to its lowest position, the distance between it and the top of the pelletizing screen 5 is 1mm to 4mm. Specifically, a certain gap is left between the pelletizing protrusions 32 and the pelletizing mesh 5, mainly to avoid direct friction between the pelletizing protrusions 32 and the pelletizing mesh 5, which would cause the pelletizing mesh 5 to break due to long-term friction. The pelletizing mesh 5 can be food-grade stainless steel wire mesh or nylon mesh.

[0017] It should be noted that this utility model is a hand-cranked wet granulation machine for pharmaceutical production. In use, the medicine is first kneaded into appropriately sized balls. After the medicine material is kneaded into balls, it is put into the outer shell of the pressure roller 2. Before putting it in, the central rotating shaft 33 is rotated at high speed by turning the crank handle 34, which in turn drives the central rotating roller 31 to rotate. In this way, the granulation protrusions 32 on the central rotating roller 31 will squeeze the material into balls on the granulation mesh 5 in the outer frame 4 through their raised rounded arc surfaces and their flat surfaces. The squeezed material will be made into strips through the mesh of the granulation mesh 5. However, due to the poor viscosity of the medicine, the squeezed strips will break when they reach a certain length, thus forming granules that fall onto the receiving platform 6 for collection, thereby quickly completing the granulation process.

[0018] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A hand-cranked wet granulation machine for pharmaceutical production, characterized in that: The equipment includes a production workbench (1), on which a pressure roller housing (2) is installed. A pressure roller structure (3) is movably installed inside the pressure roller housing (2) via a bearing (7). A granulation frame (4) is fixedly installed on the lower surface of the production workbench (1) at the lower port of the pressure roller housing (2). A granulation screen (5) is fixedly installed on the inner side of the granulation frame (4). A receiving platform (6) is fixedly installed on the inner side of the production workbench (1) below the granulation frame (4).

2. The hand-cranked wet granulation machine for pharmaceutical production according to claim 1, characterized in that: The outer surface of the pressure roller housing (2) is provided with a feeding port (21).

3. A hand-cranked wet granulation machine for pharmaceutical production according to claim 2, characterized in that: The pressure roller structure (3) includes a central shaft (33) movably mounted on the pressure roller housing (2) via a bearing (7), a central roller (31) fixedly mounted on the outer surface of the central shaft (33), a crank handle (34) connected to one end of the central shaft (33), and a granulation protrusion (32) fixed on the outer arc surface of the central roller (31).

4. A hand-cranked wet granulation machine for pharmaceutical production according to claim 3, characterized in that: There are six of the pelletizing protrusions (32), which are evenly arranged on the outer arc surface of the central rotating wheel (31). One side of each pelletizing protrusion (32) is a rounded arc surface.

5. A hand-cranked wet granulation machine for pharmaceutical production according to claim 4, characterized in that: When the pelletizing protrusion (32) is rotated to its lowest position, the distance between it and the top of the pelletizing screen (5) is 1mm to 4mm.

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