A granulator for pharmaceutical production

Abstract

The utility model relates to the field of granulator, disclose a granulator for medicine production, including the shell, the middle part of shell is installed with stirring granulating mechanism, the upper portion of stirring granulating mechanism is installed with cleaning mechanism, the top of shell is fixedly connected with mounting bracket, the stirring granulating mechanism includes motor, the motor is fixedly connected with mounting bracket, the output fixedly connected with the shaft of motor, the shaft is passed with mounting bracket and is rotatably connected, the middle part fixedly connected with the mounting rod of shaft, the left and right parts of mounting rod all rotatably connected with granulating roll, the outside of two granulating roll is commonly installed with granulating cylinder, the granulating cylinder sets up as the bucket shape, in the utility model, through setting up granulating cylinder as the bucket shape, and setting up the material guide cone in the lower part of granulating cylinder, can have the guiding effect to material, and avoid the material accumulation residual in granulating cylinder, cooperate granulating roll structure, can realize the fast granulation, more practical.

Description

Technical Field

[0001] This utility model relates to the field of granulators, and more particularly to a granulator for pharmaceutical production. Background Technology

[0002] In pharmaceutical manufacturing, granulators are key equipment for achieving material granulation. Their operational stability, granulation efficiency, and cleanliness directly affect drug quality and production continuity. Currently, most pharmaceutical granulators on the market employ a structure combining a mixing roller and a granulation cylinder. A motor-driven mixing component extrudes and shears the material, ultimately forming granules that meet the required specifications.

[0003] However, existing granulators still have many shortcomings in practical applications: First, traditional granulation cylinders are mostly cylindrical or straight-tube designs, and materials tend to accumulate and remain on the inner wall and bottom corners of the granulation cylinder during the granulation process. This problem is particularly prominent for highly viscous pharmaceutical materials, which not only wastes materials but may also affect the purity of subsequent batches of drugs due to the deterioration of residual materials, increasing production risks. Second, after granulation, the granulation rollers, inner wall of the granulation cylinder, and rotating shaft inside the granulator need to be thoroughly cleaned to meet the cleanliness requirements of pharmaceutical production. However, the existing equipment is mostly cleaned manually by disassembly and washing or by simple rinsing, which is not only cumbersome, time-consuming, and labor-intensive, but also inefficient. It is also difficult to thoroughly clean the dead corners inside the equipment, and the residual material debris is prone to bacterial growth, which does not meet the GMP standards for pharmaceutical production. Utility Model Content

[0004] To overcome the above shortcomings, this utility model provides a granulator for pharmaceutical production, which aims to improve the problem that traditional granulation cylinders are mostly cylindrical or straight-cylinder designs, and materials tend to accumulate and remain on the inner wall and bottom corners of the granulation cylinder during the granulation process.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: a granulator for pharmaceutical production, comprising a shell, a stirring granulation mechanism installed in the middle of the shell, a cleaning mechanism installed on the upper part of the stirring granulation mechanism, a mounting frame fixedly connected to the top of the shell, the stirring granulation mechanism including a motor, the motor fixedly connected to the mounting frame, a rotating shaft fixedly connected to the output end of the motor, the rotating shaft penetrating and rotatably connected to the mounting frame, a mounting rod fixedly connected to the middle of the rotating shaft, granulation rollers rotatably connected to the left and right sides of the mounting rod, a granulation cylinder jointly installed on the outside of the two granulation rollers, the granulation cylinder being bucket-shaped, the granulation cylinder fixedly connected to the top of the inner wall of the shell, a guide cone fixedly connected to the top of the inner wall of the granulation cylinder, the rotating shaft penetrating and rotatably connected to the granulation cylinder and the guide cone, a scraper fixedly connected to the lower part of the rotating shaft, the scraper being tightly attached to the outer wall of the granulation cylinder.

[0006] As a further description of the above technical solution:

[0007] The cleaning mechanism includes an electric telescopic rod, which is fixedly connected to a mounting frame. The output rod of the electric telescopic rod is connected to the mounting frame through and movably. A connecting plate is fixedly connected to the bottom of the output end of the electric telescopic rod, and a baffle is fixedly connected to the left side of the connecting plate.

[0008] As a further description of the above technical solution:

[0009] The cleaning mechanism also includes a cleaning pipe, the baffle sleeve is fitted outside the cleaning pipe, the cleaning pipe passes through and is rotatably connected to the rotating shaft, and a water inlet pipe is fixedly connected to the top of the cleaning pipe.

[0010] As a further description of the above technical solution:

[0011] A connecting rod is fixedly connected to the rear side of the cleaning tube, and the connecting rod is fixedly connected to the mounting bracket.

[0012] As a further description of the above technical solution:

[0013] The cleaning pipe has an inlet chamber at the top and multiple outlet chambers at the bottom, with the bottom of the outlet chambers being inclined.

[0014] As a further description of the above technical solution:

[0015] An auxiliary port is provided on the upper rear side of the baffle, and the connecting rod is slidably connected to the auxiliary port.

[0016] As a further description of the above technical solution:

[0017] A feed pipe is fixedly connected to the upper part of the outer shell, and a discharge pipe is fixedly connected to the lower part of the outer shell.

[0018] This utility model has the following beneficial effects:

[0019] 1. In this utility model, by setting the granulation cylinder in the shape of a bucket and setting a guide cone at the bottom of the granulation cylinder, the material can be guided and the material can be prevented from accumulating and remaining in the granulation cylinder. Combined with the granulation roller and other structures, rapid granulation can be achieved, making it more practical.

[0020] 2. In this utility model, by setting up the cooperation between the stirring and granulation mechanism and the cleaning pipe and other components, the inside of the granulator can be cleaned quickly and efficiently. In addition, by setting up the baffle, the water outlet cavity can be blocked when not in use to prevent material from entering and causing blockage, making it more practical. Attached Figure Description

[0021] Figure 1This is a schematic diagram of the overall three-dimensional structure of a granulator for pharmaceutical production proposed in this utility model;

[0022] Figure 2 This is a three-dimensional cross-sectional structural diagram of the outer shell of a granulator for pharmaceutical production proposed in this utility model;

[0023] Figure 3 This is a three-dimensional structural diagram of the baffle and cleaning tube of a pharmaceutical granulator proposed in this utility model.

[0024] Figure 4 This is a three-dimensional cross-sectional structural diagram of the cleaning tube of a pharmaceutical granulator proposed in this utility model.

[0025] Figure 5 This is a three-dimensional structural diagram showing the shell, stirring and granulation mechanism, and cleaning mechanism of a granulator for pharmaceutical production proposed in this utility model.

[0026] Legend:

[0027] 1. Outer shell; 2. Mixing and granulating mechanism; 3. Cleaning mechanism; 11. Feed pipe; 12. Discharge pipe; 13. Mounting frame; 21. Motor; 22. Rotating shaft; 23. Mounting rod; 24. Granulating roller; 25. Granulating cylinder; 26. Guide cone; 27. Scraper; 31. Electric telescopic rod; 32. Connecting plate; 33. Cleaning pipe; 34. Water inlet pipe; 35. Baffle; 331. Connecting rod; 332. Water inlet chamber; 333. Water outlet chamber; 351. Auxiliary port. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] Reference Figures 1-2 An embodiment of this utility model provides a granulator for pharmaceutical production, comprising a housing 1 for connecting various components, a stirring and granulation mechanism 2 installed in the middle of the housing 1 for granulation of pharmaceutical products, a cleaning mechanism 3 installed on the upper part of the stirring and granulation mechanism 2 for cleaning the stirring and granulation mechanism 2, a mounting bracket 13 fixedly connected to the top of the housing 1 for mounting the stirring and granulation mechanism 2 and the cleaning mechanism 3, a feed pipe 11 fixedly connected to the upper part of the housing 1 for feeding materials, and a discharge pipe 12 fixedly connected to the lower part of the housing 1 for discharging materials.

[0030] like Figures 3-5 As shown, the mixing and granulation mechanism 2 includes a motor 21, which provides power to the mechanism. The motor 21 is fixedly connected to the mounting frame 13. A rotating shaft 22 is fixedly connected to the output end of the motor 21, which is used to connect various components. The rotating shaft 22 passes through and is rotatably connected to the mounting frame 13. A mounting rod 23 is fixedly connected to the middle of the rotating shaft 22, which is used to install two granulation rollers 24. Granulation rollers 24 are rotatably connected to the left and right sides of the mounting rod 23, which can granulate by rotating in conjunction with the granulation cylinder 25. The outer surfaces of the two granulation rollers 24 are... The granulation cylinder 25 is installed with fine holes to facilitate granulation. The granulation cylinder 25 is shaped like a bucket to facilitate material guidance and prevent material accumulation. The granulation cylinder 25 is fixedly connected to the top of the inner wall of the outer shell 1. A guide cone 26 is fixedly connected to the top of the inner wall of the granulation cylinder 25 to guide the material. The rotating shaft 22 passes through and is rotatably connected to the granulation cylinder 25 and the guide cone 26. A scraper 27 is fixedly connected to the lower part of the rotating shaft 22 to scrape off the produced material in time. The scraper 27 is in close contact with the outer wall of the granulation cylinder 25.

[0031] Furthermore, the cleaning mechanism 3 includes an electric telescopic rod 31, which is used to adjust the position of the baffle 35. The electric telescopic rod 31 is fixedly connected to the mounting frame 13. The output rod of the electric telescopic rod 31 passes through and is movably connected to the mounting frame 13. A connecting plate 32 is fixedly connected to the bottom of the output end of the electric telescopic rod 31, which is used to control the baffle 35. The baffle 35 is fixedly connected to the left side of the connecting plate 32. The cleaning mechanism 3 also includes a cleaning pipe 33, which is used to spray water to clean the stirring and granulation mechanism 2. The baffle 35 is sleeved on the outside of the cleaning pipe 33 to cooperate with the use of the water outlet chamber 333. The cleaning pipe 33 passes through and is rotatably connected to the rotating shaft 22. A water inlet pipe 34 is fixedly connected to the top of the cleaning pipe 33, which is connected to the water pump through the pipe.

[0032] Furthermore, a connecting rod 331 is fixedly connected to the rear side of the cleaning pipe 33 for fixing the cleaning pipe 33. The connecting rod 331 is fixedly connected to the mounting bracket 13. The upper part of the cleaning pipe 33 has an inlet chamber 332 for facilitating the entry of liquid and for conveying it to the outlet chamber 333. The lower part of the inlet chamber 332 has multiple outlet chambers 333. The lower part of the outlet chambers 333 is inclined. The upper rear side of the baffle 35 has an auxiliary port 351 for facilitating the movement of the connecting rod 331. The connecting rod 331 is slidably connected to the auxiliary port 351.

[0033] Working Principle: During production, the material is fed into the granulation cylinder 25 through the feed pipe 11. Then, the motor 21 is turned on, which drives the fixed rotating shaft 22 to rotate. When the rotating shaft 22 rotates, the fixed mounting rod 23 is also driven, thereby driving the granulation roller 24 to make a circular motion. During the rotation, the granulation roller 24 forms a squeezing fit with the granulation cylinder 25 fixed to the top of the inner wall of the outer shell 1. Under the combined action of the stirring thrust of the granulation roller 24 and the resistance force of the inner wall of the granulation cylinder 25, the raw material is squeezed through the fine holes of the granulation cylinder 25 to form pharmaceutical granules that meet the specifications. The formed granules adhere to the outer wall of the granulation cylinder 25 and rotate synchronously with the scraper plate 27 fixedly connected to the lower part of the rotating shaft 22. The scraper plate 27 scrapes off the attached granules in time to prevent the granules from sticking and accumulating. The scraped granules fall under the action of gravity and are finally discharged from the equipment through the discharge pipe 12 fixedly connected to the lower part of the outer shell 1, completing the granulation process.

[0034] After granulation is completed, the cleaning mechanism 3 is activated to perform targeted cleaning of the mixing and granulation mechanism 2 to prevent residual raw materials from affecting the quality of subsequent batches of medicine. At this time, the electric telescopic rod 31 fixed to the mounting frame 13 is activated, and its output rod drives the connecting plate 32 fixed at the bottom to move upward, thereby driving the baffle 35 fixed on the left side of the connecting plate 32 to rise synchronously, exposing the water outlet chamber 333. Then, the external water pump is activated, and cleaning water is injected into the water inlet chamber 332 opened at the top of the cleaning pipe 33 through the water inlet pipe 34. The water inlet chamber 332 evenly distributes the water flow. Multiple water outlet chambers 333 are provided at the bottom. The lower part of the water outlet chambers 333 is inclined to optimize the water jet angle. The water can be accurately sprayed onto key granulation components such as the granulation roller 24, the inner wall of the granulation cylinder 25, and the guide cone 26. The stirring granulation mechanism 2 can also be activated to assist in cleaning. The wastewater is guided down by the bucket-shaped structure of the granulation cylinder 25 and finally discharged from the equipment through the discharge pipe 12 to complete the entire cleaning process. After cleaning, the water pump is turned off, and the electric telescopic rod 31 will control the baffle 35 to move downward, thereby blocking the water outlet chambers 333.

[0035] Additionally, it should be noted that components not described in detail in this article are existing technologies.

[0036] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A granulator for pharmaceutical production, comprising a casing (1), characterized in that: A stirring and granulating mechanism (2) is installed in the middle of the outer shell (1), and a cleaning mechanism (3) is installed on the upper part of the stirring and granulating mechanism (2). A mounting frame (13) is fixedly connected to the top of the outer shell (1). The stirring and granulating mechanism (2) includes a motor (21), which is fixedly connected to the mounting frame (13). A rotating shaft (22) is fixedly connected to the output end of the motor (21). The rotating shaft (22) is rotatably connected to the mounting frame (13). A mounting rod (23) is fixedly connected to the middle of the rotating shaft (22). The left and right sides of the granulation cylinder (24) are rotatably connected. A granulation cylinder (25) is installed on the outside of the two granulation cylinders (24). The granulation cylinder (25) is shaped like a bucket. The granulation cylinder (25) is fixedly connected to the top of the inner wall of the outer shell (1). A guide cone (26) is fixedly connected to the top of the inner wall of the granulation cylinder (25). The rotating shaft (22) passes through and is rotatably connected to the granulation cylinder (25) and the guide cone (26). A scraper (27) is fixedly connected to the lower part of the rotating shaft (22). The scraper (27) is in close contact with the outer wall of the granulation cylinder (25).

2. The granulator for pharmaceutical production according to claim 1, characterized in that: The cleaning mechanism (3) includes an electric telescopic rod (31), which is fixedly connected to the mounting frame (13). The output rod of the electric telescopic rod (31) is connected to the mounting frame (13) through and movably. A connecting plate (32) is fixedly connected to the bottom of the output end of the electric telescopic rod (31), and a baffle (35) is fixedly connected to the left side of the connecting plate (32).

3. A granulator for pharmaceutical production according to claim 2, characterized in that: The cleaning mechanism (3) also includes a cleaning pipe (33), the baffle (35) is sleeved on the outside of the cleaning pipe (33), the cleaning pipe (33) is connected to the rotating shaft (22) through and rotatably, and the top of the cleaning pipe (33) is fixedly connected to a water inlet pipe (34).

4. A granulator for pharmaceutical production according to claim 3, characterized in that: A connecting rod (331) is fixedly connected to the rear side of the cleaning tube (33), and the connecting rod (331) is fixedly connected to the mounting bracket (13).

5. A granulator for pharmaceutical production according to claim 4, characterized in that: The cleaning pipe (33) has an inlet chamber (332) at the top and an outlet chamber (333) at the bottom. The outlet chamber (333) is inclined at the bottom.

6. A granulator for pharmaceutical production according to claim 4, characterized in that: An auxiliary port (351) is provided on the upper rear side of the baffle (35), and the connecting rod (331) is slidably connected to the auxiliary port (351).

7. A granulator for pharmaceutical production according to claim 1, characterized in that: The upper part of the outer shell (1) is fixedly connected to a feed pipe (11), and the lower part of the outer shell (1) is fixedly connected to a discharge pipe (12).

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