Filling positioning mechanism for microfluidic detection device

Abstract

The application discloses a filling positioning mechanism for a microfluidic detection device, which is used for being installed on the microfluidic detection device and located above a microfluidic chip. The filling positioning mechanism comprises a driving part and a filling positioning assembly. The filling positioning assembly comprises a swing arm and a filling positioning part. The first end of the swing arm is connected with the driving part and swings in the plane parallel to the microfluidic chip under the driving of the driving part. The second end opposite to the first end of the swing arm is connected with the filling positioning part and is movable along the length direction of the swing arm. The filling positioning part is provided with a filling structure. The filling structure swings with the swing arm and moves relative to the length direction of the swing arm, so that the liquid outlet of the filling structure is aligned with the injection inlet on the microfluidic chip. The application solves the problem that the positioning pin needs high machining precision to meet the high-precision positioning requirement of the filling structure in the prior art, and the machining cost and detection cost are high.

Description

Technical Field

[0001] This application relates to the field of detection technology, and more specifically, to a dispensing and positioning mechanism for a microfluidic detection device. Background Technology

[0002] Microfluidic chip technology integrates basic operational units such as sample preparation, reaction, separation, and detection in biological, chemical, and medical analysis processes onto a single chip at the micrometer scale. Microfluidic detection devices are typically equipped with a dispensing needle. The accuracy of the relative position between the dispensing needle's outlet and the microfluidic chip's injection port directly affects the dispensing effect when the sample or reagent is injected into the microfluidic chip.

[0003] In related technologies, locating pins are typically used to position the sample dispensing needle. When the positioning accuracy of the sample dispensing needle is high, such as when the gap between the sample dispensing needle and the injection port of the microfluidic chip is small (less than 0.1 mm), the locating pin needs to be manufactured with high precision to meet the high-precision positioning requirements of the sample dispensing needle, resulting in high manufacturing and testing costs. Utility Model Content

[0004] The main objective of this application is to provide a filling and positioning mechanism for a microfluidic detection device, in order to solve the problem that in the prior art, when a positioning pin is used to position the filling structure, the positioning pin needs to have high machining accuracy to meet the high-precision positioning requirements of the filling structure, resulting in high machining and testing costs.

[0005] According to one aspect of this application, a dispensing and positioning mechanism for a microfluidic detection device is provided, the dispensing and positioning mechanism being mounted on the microfluidic detection device and positioned above the microfluidic chip, the dispensing and positioning mechanism comprising: Drive unit; A dispensing positioning assembly includes a swing arm and a dispensing positioning part. The first end of the swing arm is connected to the driving part and swings in a plane parallel to the microfluidic chip under the drive of the driving part. The dispensing positioning part is connected to the second end of the swing arm opposite to the first end and can move along the length direction of the swing arm. The dispensing positioning part has a dispensing structure. The dispensing structure swings with the swing arm and moves relative to the length direction of the swing arm so that the liquid outlet of the dispensing structure is aligned with the injection port on the microfluidic chip.

[0006] Furthermore, the filling and positioning part includes: A positioning structure is provided, which is connected to the swing arm and is movable relative to the length direction of the swing arm. The end of the positioning structure away from the swing arm is fixedly connected to the filling structure.

[0007] Furthermore, one of the positioning structure and the swing arm is provided with a groove, and the other is provided with a sliding part. The sliding part extends into the groove and slides along the inner wall of the groove. The depth direction of the groove is the same as the length direction of the swing arm.

[0008] Furthermore, the sliding part is provided with an elastic protrusion, and the inner wall surface of the groove is provided with a stop part. The elastic protrusion abuts against the inner wall surface of the groove, and the elastic protrusion abuts against the stop part to confine the sliding part within the groove.

[0009] Furthermore, a rack is provided on one of the positioning structure and the swing arm, and a gear that meshes with the rack is provided on the other. The length direction of the rack is the same as the length direction of the swing arm.

[0010] Furthermore, a first through hole is provided on the positioning structure along the height direction of the swing arm; The filling structure includes: A connecting part is detachably connected to the positioning structure, and a second through hole is provided in the connecting part along the thickness direction of the swing arm; A filling needle is provided, which passes through the first through hole and the second through hole and is fixedly connected to the connecting part. The liquid outlet is provided at the bottom end of the filling needle. The top end of the filling needle is connected to a connector, which is used at least for injecting liquid into the filling needle.

[0011] Furthermore, the filling and positioning mechanism also includes: A locking component is detachably disposed between the swing arm and the filling positioning part to lock or unlock the filling positioning part to the swing arm.

[0012] Furthermore, one of the swing arm and the filling positioning part is provided with a strip-shaped through hole, and the other is provided with a threaded hole, wherein the strip-shaped through hole extends a predetermined length along the length direction of the swing arm; The locking component includes: A locking screw, which passes through the strip-shaped through hole and engages with the threaded hole.

[0013] Furthermore, the length of the strip-shaped through hole is L, where 2mm≤L≤4mm.

[0014] Furthermore, the filling and positioning mechanism also includes: A lifting component is fixedly connected to the driving unit. Along the height direction of the swing arm, the lifting component drives the driving unit to move so that the liquid outlet of the filling structure is closer to or further away from the injection port.

[0015] In this application, when the drive unit drives the swing arm to swing in a plane parallel to the microfluidic chip, the dispensing positioning unit connected to the swing arm also swings with the swing arm. Therefore, the dispensing structure of the dispensing positioning unit also swings in a plane parallel to the microfluidic chip. Simultaneously, the dispensing structure can also move relative to the length direction of the swing arm. That is, the dispensing structure can swing both in a plane parallel to the microfluidic chip and move relative to the length direction of the swing arm. Therefore, the dispensing structure can move to any position in the plane parallel to the microfluidic chip, aligning the outlet of the dispensing structure with the injection port of the microfluidic chip, ensuring that the reagent or sample in the dispensing structure can be accurately injected into the microfluidic chip, thereby ensuring high detection accuracy of the microfluidic detection device. Compared to existing technologies, this application can achieve precise positioning of the filling structure through the swing arm and the filling positioning part. Without relying on high processing precision, this application can also accurately position the filling structure so that the liquid outlet of the filling structure is aligned with the injection port of the microfluidic chip. The processing cost is lower, which helps to reduce the detection cost of the microfluidic detection device. Attached Figure Description

[0016] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, are illustrative and descriptive, serving to explain this application and do not constitute an undue limitation thereof. In the drawings: Figure 1 This is a top view of the injection positioning mechanism disclosed in this application; Figure 2 This is a three-dimensional view of the positioning and affixing mechanism disclosed in this application.

[0017] The above figures include the following reference numerals: 10. Microfluidic chip; 11. Injection port; 20. Drive unit; 30. Injection positioning assembly; 31. Swing arm; 32. Injection positioning unit; 321. Injection structure; 3211. Outlet; 3212. Sliding part; 3213. Connecting part; 3214. Injection needle; 3215. Connector; 3216. Second through hole; 322. Positioning structure; 3221. Groove; 3222. First through hole; 40. Locking component; 41. Strip-shaped through hole; 42. Locking screw; 50. Lifting component; 60. Base. Detailed Implementation

[0018] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. This application will now be described in detail with reference to the accompanying drawings and embodiments.

[0019] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0020] Unless otherwise specifically stated, the relative arrangement, numerical expressions, and values ​​of the components and steps described in these embodiments do not limit the scope of this application. It should also be understood that, for ease of description, the dimensions of the various parts shown in the drawings are not drawn to actual scale. Techniques, methods, and devices known to those skilled in the art may not be discussed in detail, but where appropriate, such techniques, methods, and devices should be considered part of the specification. In all examples shown and discussed herein, any specific values ​​should be interpreted as merely exemplary and not as limitations. Therefore, other examples of exemplary embodiments may have different values. It should be noted that similar reference numerals and letters in the following drawings denote similar items; therefore, once an item is defined in one drawing, it need not be further discussed in subsequent drawings.

[0021] like Figures 1 to 2 As shown, this application provides a dispensing and positioning mechanism for a microfluidic detection device. This dispensing and positioning mechanism is used to mount on the microfluidic detection device and is located above the microfluidic chip 10. The microfluidic chip 10 has at least one injection port 11. The dispensing and positioning mechanism includes a drive unit 20 and a dispensing and positioning assembly 30. The dispensing and positioning assembly 30 includes a swing arm 31 and a dispensing and positioning part 32. The first end of the swing arm 31 is connected to the drive unit 20 and swings in a plane parallel to the microfluidic chip 10 under the drive of the drive unit 20 (the swing direction of the swing arm 31 is as follows). Figure 1 (The direction indicated by the middle arrow A). The filling positioning part 32 is connected to the second end of the swing arm 31 opposite to the first end and can be connected along the length direction of the swing arm 31 (e.g., ...). Figure 1 The middle part moves in the direction indicated by arrow X. The dispensing positioning part 32 has a dispensing structure 321. The dispensing structure 321 swings with the swing arm 31 and moves relative to the length direction of the swing arm 31 so that the liquid outlet 3211 of the dispensing structure 321 is aligned with the injection port 11 on the microfluidic chip 10.

[0022] In this embodiment, when the driving unit 20 drives the swing arm 31 to swing in a plane parallel to the microfluidic chip 10, the dispensing positioning unit 32 connected to the swing arm 31 also swings with the swing arm 31. Therefore, the dispensing structure 321 of the dispensing positioning unit 32 also swings in a plane parallel to the microfluidic chip 10. Simultaneously, the dispensing structure 321 can also move relative to the length direction of the swing arm 31. That is, the dispensing structure 321 can swing in a plane parallel to the microfluidic chip 10 and move relative to the length direction of the swing arm 31. Therefore, the dispensing structure 321 can move to any position in a plane parallel to the microfluidic chip 10, so that the outlet 3211 of the dispensing structure 321 is aligned with the injection port 11 of the microfluidic chip 10, ensuring that the reagent or sample in the dispensing structure 321 can be accurately injected into the microfluidic chip 10, thereby ensuring that the microfluidic detection device has high detection accuracy. Compared with the prior art, this application can achieve precise positioning of the filling structure 321 through the swing arm 31 and the filling positioning part 32. The swing arm 31 and the filling positioning part 32 do not need to rely on high processing accuracy. This application can also accurately position the filling structure 321 so that the liquid outlet 3211 of the filling structure 321 is aligned with the injection port 11 of the microfluidic chip 10. The processing cost is lower, which is conducive to reducing the detection cost of the microfluidic detection device.

[0023] Furthermore, the dispensing structure 321 first oscillates in a plane parallel to the microfluidic chip 10, allowing for coarse adjustment of its position to bring it closer to the injection port 11 on the microfluidic chip 10. Then, the dispensing structure 321 moves along the X-direction for fine adjustment, aligning its outlet 3211 with the injection port 11 on the microfluidic chip 10. This embodiment achieves precise positioning of the dispensing structure 321 through a combination of coarse and fine adjustments, ensuring greater controllability of its positioning accuracy and more stable alignment between the outlet 3211 and the injection port 11, thereby improving the stability and reliability of the dispensing effect.

[0024] In actual testing, changes in testing requirements often lead to changes in the specifications of the microfluidic chip 10, necessitating the redesign and fabrication of high-precision positioning pins, which not only increases costs but also extends the testing cycle. However, the position adjustment of the dispensing structure 321 in this application offers greater flexibility, adapting to various specifications of microfluidic chips 10. Under different testing requirements, the dispensing structure 321 of this application can still accurately perform the dispensing operation, reducing testing costs and shortening the testing cycle.

[0025] In this application, the microfluidic chip 10 has multiple injection ports 11. After the injection structure 321 is oscillating and moving, the liquid outlet 3211 of the injection structure 321 is precisely aligned with one of the injection ports 11 to be added.

[0026] Furthermore, the dispensing positioning unit 32 includes a positioning structure 322. The positioning structure 322 is connected to the swing arm 31 and is movable relative to the length direction of the swing arm 31. The end of the positioning structure 322 away from the swing arm 31 is fixedly connected to the dispensing structure 321. The positioning structure 322 is connected between the swing arm 31 and the dispensing structure 321, and can transmit the swinging motion to the dispensing structure 321, causing the dispensing structure 321 to swing. In addition, the positioning structure 322 is movable relative to the length direction of the swing arm 31, thereby driving the dispensing structure 321 to move relative to the length direction of the swing arm 31.

[0027] In some embodiments, the positioning structure 322 is provided with a groove 3221, and the swing arm 31 is provided with a sliding portion 3212. In other embodiments, the positioning structure 322 is provided with a sliding portion 3212, and the swing arm 31 is provided with a groove 3221. The sliding portion 3212 extends into the groove 3221 and slides along the inner wall surface of the groove 3221, the depth direction of the groove 3221 being the same as the length direction of the swing arm 31. The sliding portion 3212 extending into the groove 3221 and sliding along the depth direction of the groove 3221 allows the positioning structure 322 to move relative to the length direction of the swing arm 31, thereby driving the filling structure 321 to move in the X direction.

[0028] The groove 3221 is simple to process and has a low processing cost. The inner wall surface of the groove 3221 can guide the sliding trajectory of the sliding part 3212, ensuring that the sliding part 3212 moves in the X direction. In addition, the groove 3221 also has a predetermined protective function, protecting the sliding part 3212 from damage from the external environment that would affect the displacement accuracy of the sliding part 3212.

[0029] In some embodiments, the sliding portion 3212 has an elastic protrusion, and the inner wall surface of the groove 3221 has a stop portion. The elastic protrusion abuts against the inner wall surface of the groove 3221, and the elastic protrusion abuts against the stop portion to confine the sliding portion 3212 within the groove 3221. The protrusion direction of the elastic protrusion intersects the X direction. Generally, the elastic protrusion is provided at the end of the sliding portion 3212. When the sliding portion 3212 slides along the X direction and toward the bottom of the groove 3221, when the elastic protrusion of the sliding portion 3212 abuts against the stop portion, the stop portion prevents the sliding portion 3212 from continuing to slide, thereby confining the sliding portion 3212 within the groove 3221 and preventing the sliding portion 3212 from disengaging from the groove 3221. The elastic protrusion abuts against the inner wall of the groove 3221, which increases the friction between the elastic protrusion and the inner wall of the groove 3221. The elastic protrusion compensates for the fit gap between the sliding part 3212 and the groove 3221 through its own elastic deformation, reducing the lateral movement of the sliding part 3212 during the sliding process, making the movement of the positioning structure 322 along the length of the swing arm 31 smoother, and improving the accuracy of fine adjustment. Especially in the scenario where the liquid outlet 3211 and the injection port 11 are aligned at the micron level, the adjustment error caused by the fit gap can be further reduced.

[0030] Specifically, when the sliding part 3212 is fitted into the groove 3221, the volume of the elastic protrusion decreases when it deforms, thus allowing it to be smoothly assembled into the groove 3221. In this embodiment, the stop part is the inner wall surface at the opening of the groove 3221, but the specific structure of the stop part is not uniquely limited. As long as the stop part can stop the elastic protrusion to prevent the sliding part 3212 from continuing to slide, it is within the protection scope of this application.

[0031] In some embodiments, the positioning structure 322 is provided with a rack, and the rocker arm 31 is provided with a gear that meshes with the rack. The length direction of the rack is the same as the length direction of the rocker arm 31. The gear rotates to move on the rack, thereby driving the positioning structure 322 to move in the X direction. The gear is rotatably connected to the rocker arm 31.

[0032] In other embodiments, the rocker arm 31 is provided with a rack, and the positioning structure 322 is provided with a gear that meshes with the rack. The length direction of the rack is the same as the length direction of the rocker arm 31. The gear rotates to move on the rack, thereby driving the positioning structure 322 to move in the X direction. The gear and the positioning structure 322 are rotatably connected. When the gear moves on the rack, the gear can also have high movement accuracy, thereby achieving precise adjustment of the position of the liquid outlet 3211.

[0033] In some embodiments, along the height direction of the swing arm 31 (e.g.) Figure 2(In the direction indicated by the middle arrow Y), a first through hole 3222 is provided through the positioning structure 322. The filling structure 321 includes a connecting part 3213 and a filling needle 3214. The connecting part 3213 is detachably connected to the positioning structure 322, and a second through hole 3216 is provided through the connecting part 3213 along the thickness direction of the swing arm 31. The filling needle 3214 passes through the first through hole 3222 and the second through hole 3216 and is fixedly connected to the connecting part 3213. The liquid outlet 3211 is provided at the bottom end of the filling needle 3214, and a connector 3215 is connected to the top end of the filling needle 3214. The connector 3215 is used at least for injecting liquid into the filling needle 3214. In actual use, the filling structure 321 generally uses disposable consumables, and the connecting part 3213 is detachably connected to the positioning structure 322 to ensure easy installation and replacement of the filling structure 321. During installation, the injection needle 3214 is fixed inside the second through hole 3216, and the injection needle 3214 passes through the first through hole 3222, with the connecting part 3213 abutting against the positioning structure 322. Then, screws, positioning pins, or other structures are used to lock and fix the connecting part 3213 and the positioning structure 322 together. Understandably, the liquid injected into the injection needle 3214 includes samples, reagents, cleaning solutions, etc., but is not limited to these.

[0034] Specifically, the connecting part 3213 can be configured as a plate structure. The bottom of the dispensing needle 3214 is provided with an outlet 3211. When the dispensing structure 321 oscillates and moves along the X direction, it causes the outlet 3211 at the bottom of the dispensing needle 3214 to oscillate and move, thereby aligning the outlet 3211 with the injection port 11. The connector 3215 at the top of the dispensing needle 3214 communicates with the dispensing needle 3214, allowing reagents or samples to be injected into the dispensing needle 3214 through the connector 3215 and flow out from the outlet 3211.

[0035] In some embodiments, the dispensing positioning mechanism further includes a locking component 40. The locking component 40 is detachably disposed between the swing arm 31 and the dispensing positioning part 32 to lock or unlock the dispensing positioning part 32 to the swing arm 31. When the outlet 3211 of the dispensing needle 3214 moves to align with the injection port 11, to prevent the position of the outlet 3211 from changing, this embodiment uses the locking component 40 to lock the swing arm 31 and the positioning structure 322 together, thereby ensuring that the outlet 3211 is aligned with the injection port 11. After dispensing is completed, the locking component 40 unlocks the swing arm 31 and the positioning structure 322, allowing the positioning structure 322 to be readjusted.

[0036] The swing arm 31 and the filling positioning part 32 each have a strip-shaped through hole 41 and a threaded hole, respectively. The strip-shaped through hole 41 extends a predetermined length along the length direction of the swing arm 31. The locking component 40 includes a locking screw 42, which passes through the strip-shaped through hole 41 and engages with the threaded hole. When the positioning structure 322 moves into place along the X direction, the locking screw 42 passes through the strip-shaped through hole 41 and engages with the threaded hole, thereby locking the positioning structure 322 onto the swing arm 31. The locking screw 42 can move within the strip-shaped through hole 41, ensuring that the locking screw 42 can always pass through the strip-shaped through hole 41 and engage with the threaded hole after the positioning structure 322 moves. The strip-shaped through hole 41 and the threaded hole are simple to manufacture and have lower costs.

[0037] Furthermore, the length of the strip-shaped through-hole 41 is L, where 2mm ≤ L ≤ 4mm. L can be set to one of the following: 2mm, 2.1mm, 2.2mm, 2.3mm, 2.4mm, 2.5mm, 2.6mm, 2.7mm, 2.8mm, 2.9mm, 3mm, 3.1mm, 3.2mm, 3.3mm, 3.4mm, 3.5mm, 3.6mm, 3.7mm, 3.8mm, 3.9mm, 4mm, etc. The length of the strip-shaped through-hole 41 can meet the position adjustment requirements of the positioning structure 322, and can also avoid excessive movement of the filling positioning part 32 through the limited length constraint, ensuring that the adjustment process always focuses on the effective alignment range, and improving the positioning efficiency in high-precision scenarios (such as gaps less than 0.1 mm). The adjustable stroke within this length range allows for more precise control by operators, reducing the risk of structural collisions caused by excessive adjustment. This further ensures the safety and stability of the alignment process between the liquid outlet 3211 of the filling structure 321 and the chip injection port 11. Simultaneously, the quick locking or unlocking function of the locking screw 42 creates an efficient connection between precise adjustment and stable locking, improving overall testing efficiency. If L < 2mm, the length of the strip-shaped through-hole 41 is too small to meet the displacement adjustment requirements of the positioning structure 322. If L > 4mm, the length of the strip-shaped through-hole 41 is too large, leading to ineffective adjustment of the positioning structure 322 and affecting its structural strength.

[0038] Furthermore, the filling and positioning mechanism also includes a lifting component 50, which is fixedly connected to the drive unit 20. Along the height direction of the swing arm 31, the lifting component 50 drives the drive unit 20 to move so that the outlet 3211 of the filling structure 321 moves closer to or further away from the injection port 11. In the Y direction, the lifting component 50 drives the drive unit 20 to move up and down, and the drive unit 20, through the positioning structure 322, drives the filling structure 321 to move up and down, so that the outlet 3211 moves closer to or further away from the injection port 11. The lifting component 50 can be electrically powered to achieve more accurate positioning of the positioning structure 322.

[0039] In this embodiment, both the swing arm 31 and the positioning structure 322 can be configured as plate-like structures, which facilitates processing and reduces costs. This application achieves precise positioning during assembly by adjusting the overall length of the swing arm 31 and the positioning structure 322 through a simple adjustable positioning and filling structure 321. This significantly reduces the precision requirements of machined parts, thereby lowering the processing and inspection costs of the parts.

[0040] During actual adjustment, the theoretically designed distance from the rotation center of the swing arm 31 to the center of the injection hole in the filling position is M; after assembly, the actual distance from the rotation center of the swing arm 31 to the center of the injection hole in the filling position is M1. This application solves the machining errors of M and M1 in a low-cost way. The lifting component 50 and the microfluidic chip 10 are both mounted on the base 60.

[0041] For ease of description, spatial relative terms such as "above," "on top of," "on the upper surface of," "above," etc., are used herein to describe the spatial positional relationship of a device or feature as shown in the figures to other devices or features. It should be understood that spatial relative terms are intended to encompass different orientations in use or operation beyond the orientation of the device as described in the figures. For example, if the device in the figures were inverted, a device described as "above" or "on top of" other devices or structures would subsequently be positioned as "below" or "under" other devices or structures. Thus, the exemplary term "above" can include both "above" and "below." The device may also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used herein will be interpreted accordingly.

[0042] Furthermore, it should be noted that the use of terms such as "first" and "second" to define components is merely for the purpose of distinguishing the corresponding components. Unless otherwise stated, the above terms have no special meaning and therefore cannot be construed as limiting the scope of protection of this application.

[0043] The above are merely preferred embodiments of this application and are not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A dispensing and positioning mechanism for a microfluidic detection device, characterized in that, The dispensing positioning mechanism is used to install on the microfluidic detection device and is located above the microfluidic chip (10). The dispensing positioning mechanism includes: Drive unit (20); The dispensing positioning assembly (30) includes a swing arm (31) and a dispensing positioning part (32). The first end of the swing arm (31) is connected to the driving part (20) and swings in a plane parallel to the microfluidic chip (10) under the drive of the driving part (20). The dispensing positioning part (32) is connected to the second end of the swing arm (31) opposite to the first end and can move along the length direction of the swing arm (31). The dispensing positioning part (32) has a dispensing structure (321). The dispensing structure (321) swings with the swing arm (31) and moves relative to the length direction of the swing arm (31) so that the outlet (3211) of the dispensing structure (321) is aligned with the injection port (11) on the microfluidic chip (10).

2. The dispensing and positioning mechanism for a microfluidic detection device according to claim 1, characterized in that, The filling and positioning part (32) includes: The positioning structure (322) is connected to the swing arm (31) and can move relative to the length direction of the swing arm (31). The end of the positioning structure (322) away from the swing arm (31) is fixedly connected to the filling structure (321).

3. The dispensing and positioning mechanism for a microfluidic detection device according to claim 2, characterized in that, One of the positioning structure (322) and the swing arm (31) is provided with a groove (3221), and the other is provided with a sliding part (3212). The sliding part (3212) extends into the groove (3221) and slides along the inner wall of the groove (3221). The depth direction of the groove (3221) is the same as the length direction of the swing arm (31).

4. The dispensing and positioning mechanism for a microfluidic detection device according to claim 3, characterized in that, The sliding part (3212) is provided with an elastic protrusion, and the inner wall surface of the groove (3221) is provided with a stop part. The elastic protrusion abuts against the inner wall surface of the groove (3221), and the elastic protrusion abuts against the stop part to limit the sliding part (3212) within the groove (3221).

5. The dispensing and positioning mechanism for a microfluidic detection device according to claim 2, characterized in that, A rack is provided on one of the positioning structure (322) and the swing arm (31), and a gear that meshes with the rack is provided on the other. The length direction of the rack is the same as the length direction of the swing arm (31).

6. The dispensing and positioning mechanism for a microfluidic detection device according to claim 2, characterized in that, Along the height direction of the swing arm (31), a first through hole (3222) is provided on the positioning structure (322). The filling structure (321) includes: The connecting part (3213) is detachably connected to the positioning structure (322), and the connecting part (3213) is provided with a second through hole (3216) through the thickness direction of the swing arm (31). A filling needle (3214) is inserted through the first through hole (3222) and the second through hole (3216) and is fixedly connected to the connecting part (3213). The liquid outlet (3211) is located at the bottom end of the filling needle (3214). The top end of the filling needle (3214) is connected to a connector (3215), which is at least used to inject liquid into the filling needle (3214).

7. The dispensing and positioning mechanism for a microfluidic detection device according to any one of claims 1 to 6, characterized in that, Also includes: A locking component (40) is detachably disposed between the swing arm (31) and the filling positioning part (32) to lock or unlock the filling positioning part (32) to the swing arm (31).

8. The dispensing and positioning mechanism for a microfluidic detection device according to claim 7, characterized in that, One of the swing arm (31) and the filling positioning part (32) is provided with a strip-shaped through hole (41), and the other is provided with a threaded hole. The strip-shaped through hole (41) extends a predetermined length along the length direction of the swing arm (31). The locking component (40) includes: A locking screw (42) passes through the strip-shaped through hole (41) and engages with the threaded hole.

9. The dispensing and positioning mechanism for a microfluidic detection device according to claim 8, characterized in that, The length of the strip-shaped through hole (41) is L, where 2mm≤L≤4mm.

10. The dispensing and positioning mechanism for a microfluidic detection device according to any one of claims 1 to 6, characterized in that, Also includes: The lifting component (50) is fixedly connected to the driving part (20). Along the height direction of the swing arm (31), the lifting component (50) drives the driving part (20) to move so that the liquid outlet (3211) of the filling structure (321) is close to or away from the injection port (11).

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