Stem cell transportation and storage device with good stability

Abstract

The utility model belongs to stem cell transportation and storage device technical field, concretely relates to a stem cell transportation and storage device with good stability, including the transfer case body, the transfer case body one side utilizes the hinge rotation and links the box cover, the other side surface of box cover connects the connecting lug, the connecting lug surface utilizes the knurl bolt and is connected in the fixed block, the fixed block surface is connected in the transfer case body open -ended surface, the transfer case body inner wall surface connects the side plate, the trapezoidal groove is set up in the side plate surface, the trapezoidal groove surface inserts the lower clamping block, the lower clamping block surface bonds the lower rubber block, the lower rubber block surface is connected in the trapezoidal groove surface, and the lower clamping block surface connects the rack. The utility model, through the rack and the upper pressure frame of clamping on the side plate, the stem cell containing vessel needing to be transferred and temporarily stored is accurately fixed, improves its stability of placing, avoids the collision breakage of container due to the gap between container and fixed groove in the course of transfer.

Description

Technical Field

[0001] This utility model belongs to the technical field of stem cell transport and storage devices, specifically relating to a stem cell transport and storage device with good stability. Background Technology

[0002] In the modern biomedical field, stem cells, due to their unique self-renewal capacity and multi-directional differentiation potential, have become a core research subject in cutting-edge areas such as cell therapy, regenerative medicine, and drug development. From hematopoietic stem cell transplantation for treating blood system diseases to the application of mesenchymal stem cells for repairing organ damage, stem cell technology is gradually moving from the laboratory to the clinic, providing new possibilities for overcoming intractable diseases. However, the bioactivity of stem cells is highly susceptible to external environmental influences—temperature fluctuations, mechanical vibrations, changes in light intensity, and imbalances in the gas environment can all lead to decreased cell activity, impaired function, or even complete loss of clinical application value. This characteristic makes the transportation and storage of stem cells a key bottleneck restricting their clinical translation: how to construct a stable, safe, and controllable "living environment" for stem cells throughout the entire chain from the laboratory to the hospital, from the preparation center to the patient's bedside, is directly related to therapeutic efficacy and medical safety. With the large-scale development of stem cell clinical research and the deepening of cross-regional cooperation, the distance of sample transportation is constantly increasing, and the demand for the portability, battery life and intelligent monitoring of storage devices is also increasing. Existing transport boxes mostly use uniform grid-shaped slots or foam grooves, which are difficult to match with storage containers of different sizes (such as 2ml cryopreservation tubes, 15ml centrifuge tubes, cell culture flasks, etc.). There are gaps between the containers and the slots, which can easily cause lateral sliding or rotation during transportation, leading to collision damage to the containers. Especially in deep cryogenic environments, cryopreservation tubes are more prone to breakage due to the brittleness of the material. Utility Model Content

[0003] The purpose of this invention is to provide a stem cell transport and storage device with good stability, aiming to solve the problem that existing transport boxes mostly use uniform grid-shaped slots or foam grooves, which are difficult to match storage containers of different sizes (such as 2ml cryopreservation tubes, 15ml centrifuge tubes, cell culture flasks, etc.). There are gaps between the containers and the slots, which can easily cause lateral sliding or rotation during transportation, resulting in collision damage to the containers. Especially in deep cryogenic environments, cryopreservation tubes are more prone to breakage due to material brittleness.

[0004] To achieve the above objectives, this utility model provides the following technical solution: a stem cell transport and storage device with good stability, comprising a transport box body, a box cover hinged to one side of the transport box body, a connecting ear connected to the other side surface of the box cover, the connecting ear being threaded to a fixing block using knurled bolts, the fixing block being connected to the open end surface of the transport box body, a side plate connected to the inner wall surface of the transport box body, a trapezoidal groove formed on the side plate surface, a lower locking block inserted into the trapezoidal groove surface, a lower rubber block adhered to the lower locking block surface, the lower rubber block being engaged with the trapezoidal groove surface, a placement rack connected to the lower locking block surface, a placement groove formed on the top surface of the placement rack, a rubber ring adhered to the upper end surface of the placement groove, an upper pressure frame abutting the top surface of the placement rack, upper locking blocks connected to both sides of the upper pressure frame, upper rubber blocks adhered to the upper locking blocks surface, the upper rubber blocks being engaged with the trapezoidal groove surface.

[0005] As a preferred embodiment of the stem cell transport and storage device with good stability according to this utility model, both the lower and upper locking blocks are trapezoidal integrated structures, and their shapes and sizes are adapted to the trapezoidal groove. Furthermore, two semi-circular grooves are opened on the surface of the trapezoidal groove, and their shapes and sizes are adapted to the lower and upper rubber blocks.

[0006] As a preferred embodiment of the stem cell transport and storage device of this utility model with good stability, the surface of the upper pressure frame is provided with a circular through groove, the shape and size of which are adapted to the placement groove.

[0007] As a preferred embodiment of the stem cell transport and storage device of this utility model with good stability, the surface of the transport box is connected to the mounting box, the inner wall surface of the mounting box is connected to the fixing plate, the surface of the fixing plate is threadedly connected to the screw, and the surface of the screw is threadedly connected to the wing nut.

[0008] As a preferred embodiment of the stem cell transport and storage device of this utility model with good stability, the bottom surface of the butterfly nut abuts against the top of the fixed plate, the bottom surface of the screw is connected to the movable plate, the bottom surface of the movable plate is equipped with universal rollers, and the inner wall of the mounting box is slidably sleeved with the movable plate.

[0009] As a preferred embodiment of the present invention for a stem cell transport and storage device with good stability, the mounting box has a rectangular through groove longitudinally formed on its surface, the shape and size of which are adapted to the moving plate.

[0010] Compared with the prior art, the beneficial effects of this utility model are: The placement rack and upper pressure rack that snap onto the side plate are used to precisely fix the stem cell container that needs to be transported and temporarily stored, thereby improving its placement stability and preventing the container from being damaged by collision due to the gap between the container and the fixing groove during transportation. Furthermore, by utilizing two sets of height-adjustable casters installed on both sides of the transport container, the container can be moved using these casters when needed, reducing the physical burden on transport personnel. Attached Figure Description

[0011] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings: Figure 1 This is a schematic diagram of the main structure of this utility model; Figure 2 This is a schematic diagram of the structure of this utility model from below; Figure 3 This is a schematic diagram of the main cross-sectional structure of this utility model; Figure 4 This is an exploded structural diagram of the side plate and the placement rack of this utility model.

[0012] In the diagram: 1. Transfer box body; 2. Hinge; 3. Box lid; 4. Connecting lug; 5. Knurled bolt; 6. Fixing block; 7. Side plate; 8. Trapezoidal groove; 9. Lower locking block; 10. Lower rubber block; 11. Placement rack; 12. Placement groove; 13. Rubber ring; 14. Upper pressure frame; 15. Upper locking block; 16. Upper rubber block; 17. Mounting box; 18. Fixing plate; 19. Screw; 20. Wing nut; 21. Moving plate; 22. Universal roller. Detailed Implementation

[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0014] Please see Figures 1-4This utility model provides the following technical solution: A stem cell transport and storage device with good stability, including a transport box body 1, a box cover 3 is rotatably hinged to one side of the transport box body 1 by a hinge 2, a connecting ear 4 is connected to the other side surface of the box cover 3, the surface of the connecting ear 4 is threaded to a fixing block 6 by a knurled bolt 5, the surface of the fixing block 6 is connected to the open end surface of the transport box body 1, a side plate 7 is connected to the inner wall surface of the transport box body 1, a trapezoidal groove 8 is opened on the surface of the side plate 7, a lower locking block 9 is inserted into the surface of the trapezoidal groove 8, a lower rubber block 10 is bonded to the surface of the lower locking block 9, the surface of the lower rubber block 10 is engaged with the surface of the trapezoidal groove 8, a placement rack 11 is connected to the surface of the lower locking block 9, a placement groove 12 is opened on the top surface of the placement rack 11, a rubber ring 13 is bonded to the upper end surface of the placement groove 12, an upper pressure frame 14 is abutted to the top surface of the placement rack 11, upper locking blocks 15 are connected to the two sides of the upper pressure frame 14, upper rubber blocks 16 are bonded to the surface of the upper locking blocks 15, and the surface of the upper rubber blocks 16 is engaged with the surface of the trapezoidal groove 8.

[0015] Preferably, both the lower locking block 9 and the upper locking block 15 are trapezoidal integrated structures, and their shapes and dimensions are adapted to the trapezoidal groove 8. Furthermore, two semi-circular grooves are opened on the surface of the trapezoidal groove 8, and their shapes and dimensions are adapted to the lower rubber block 10 and the upper rubber block 16.

[0016] In practical use, the lower locking blocks 9 connected to both sides of the placement rack 11 are inserted into the trapezoidal groove 8 and moved downward until the lower rubber block 10 on the surface of the lower locking block 9 engages and is fixed in the groove near the lower end of the trapezoidal groove 8, thereby fixing the placement rack 11 in the position next to the side plate 7. The upper locking block 15 moves downward until the upper rubber block 16 engages and is fixed in the circular groove at the upper end of the trapezoidal groove 8, thereby fixing the position of the upper pressure rack 14 on the side plate 7.

[0017] Preferably, a circular through groove is formed on the surface of the upper pressure frame 14, the shape and size of which are adapted to the placement groove 12.

[0018] In practical use, the circular through groove on the surface of the upper pressure frame 14 will precisely align with the top of the container on the surface of the placement rack 11, and the rubber ring 13 inside the upper pressure frame 14 will be fitted onto the upper end of the container to further fix its position.

[0019] Preferred configuration: The surface of the transfer box 1 is connected to the mounting box 17, the inner wall surface of the mounting box 17 is connected to the fixing plate 18, the surface of the fixing plate 18 is threadedly connected to the screw 19, and the surface of the screw 19 is threadedly connected to the wing nut 20.

[0020] Preferably, the bottom surface of the wing nut 20 abuts against the top of the fixed plate 18, the bottom surface of the screw 19 is connected to the movable plate 21, the bottom surface of the movable plate 21 is equipped with universal rollers 22, and the inner wall of the mounting box 17 is slidably sleeved with the movable plate 21.

[0021] In practical use, loosen the wing nuts 20 on both sides of the screw 19 in sequence, and then rotate the screw 19 in sequence by the same number of turns so that the screw 19 on both sides can move down to the same height until the universal roller 22 at the bottom of the screw 19 is exposed below the mounting box 17. Then tighten the wing nuts 20 threaded on the screw 19 to lock the position of the screw 19 after the height has been adjusted.

[0022] Preferably, a rectangular through groove is formed longitudinally on the surface of the mounting box 17, the shape and size of which are adapted to the movable plate 21.

[0023] In practical use, the rectangular through groove on the surface of the mounting box 17 can be used to limit the movement range of the movable plate 21 within the mounting box 17, allowing it to move vertically downwards and thus stably support the movement of the transfer box 1.

[0024] Working principle: When stem cells need to be transported, select the appropriate placement rack 11 and upper pressure rack 14 according to the model of the container for storing stem cells. Then, unscrew the knurled bolt 5 that is threaded between the connecting ear 4 and the fixing block 6, thereby lifting the box cover 3 and allowing it to be rotated open on the top of the transport box 1 through the hinge 2 connected on the other side, exposing the opening end of the inner wall of the transport box 1. At this time, insert the lower locking blocks 9 connected on both sides of the placement rack 11 into the trapezoidal groove 8 and move them downward until the lower rubber block 10 on the surface of the lower locking block 9 engages and is fixed on the groove near the lower end of the trapezoidal groove 8, thereby fixing the placement rack 11 in the position next to the side plate 7. At this point, the stem cell containers to be transported can be inserted into the placement slots 12 one by one. Simultaneously, the silicone rubber rings 13 attached to the top of the placement slots 12 abut against the container surface, clamping and fixing them, thus stabilizing the position of the stem cell containers on the placement rack 11. After all containers are placed in the placement slots 12, the upper pressure frame 14 is lifted again, its upper locking blocks 15 on both sides inserted into the trapezoidal slots 8, and moved downwards. At this time, the circular through-slots on the surface of the upper pressure frame 14 will precisely align with the top of the containers on the surface of the placement rack 11, and the rubber rings 13 inside the upper pressure frame 14 will then secure them. At the top of the container, its position is further fixed. The silicone rubber material has the characteristics of low temperature resistance (-80℃ to 200℃) and good elasticity. It can not only tightly wrap the outer wall of the container to prevent shaking, but also buffer the slight vibration during transportation. The upper locking block 15 moves downward until the upper rubber block 16 is locked in the circular groove at the top of the trapezoidal groove 8, which can fix the position of the upper pressure frame 14 on the side plate 7. Then, through the cooperation of the upper and lower placement frames 11 and the upper pressure frame 14, the stem cell container is stably placed to prevent it from being damaged by bumps due to the gap between the container and the placement frame 11 during transportation. After placing the upper pressure frame 14, repeat the above operation again, rotate the box cover 3 in the opposite direction so that its lower pressure cover is on the opening end of the transport box body 1. At this time, the rubber plate glued to the bottom of the box cover 3 abuts against the top of the upper pressure frame 14, squeezing and clamping it, and filling the gap between the transport box body 1 and the box cover 3. At the same time, during the transport, ice can be placed on the inner wall of the transport box body 1, and the rectangular groove at the bottom of the placement rack 11 is used to fit onto the ice pack to fix its position. At the same time, the rectangular groove matches the size of the standard biological ice pack to avoid the ice pack sliding and causing uneven local temperature, thereby preserving the stem cell container on the placement rack 11 at low temperature. Then, when the transfer box 1 needs to be moved on flat ground for transfer, the wing nuts 20 on both sides of the screw 19 can be loosened in sequence, and then the screw 19 can be rotated in sequence by the same number of turns, so that the screw 19 on both sides can be moved down to the same height until the universal rollers 22 at the bottom of the screw 19 are exposed below the mounting box 17. Then the wing nuts 20 threaded on the screw 19 can be tightened to lock the position of the screw 19 after the height has been adjusted. In this way, the universal rollers 22 on both sides of the transfer box 1 can be used to support and move the transfer box 1 stably, which not only ensures the stability of the transfer box 1 during transfer, but also reduces the physical burden on the transfer personnel.

[0025] Finally, it should be noted that the above are merely preferred embodiments of this utility model and are not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A stem cell transport and storage device with good stability, comprising a transport box (1), characterized in that: The transfer box body (1) has a lid (3) hinged to one side by a hinge (2). The lid (3) has a connecting lug (4) on the other side. The connecting lug (4) is threaded to a fixing block (6) by a knurled bolt (5). The fixing block (6) is connected to the open end of the transfer box body (1). The inner wall of the transfer box body (1) is connected to a side plate (7). A trapezoidal groove (8) is formed on the surface of the side plate (7). A lower locking block (9) is inserted into the surface of the trapezoidal groove (8). A lower rubber block (10) is adhered to the surface of the lower locking block (9). The lower rubber block (10) is engaged with the surface of the trapezoidal groove (8). The lower locking block (9) is connected to the placement rack (11). The top surface of the placement rack (11) has a placement groove (12). The upper surface of the placement groove (12) is bonded with a rubber ring (13). The top surface of the placement rack (11) abuts against the upper pressure rack (14). The two sides of the upper pressure rack (14) are connected to the upper locking blocks (15). The surface of the upper locking blocks (15) is bonded with an upper rubber block (16). The surface of the upper rubber block (16) is engaged with the surface of the trapezoidal groove (8).

2. The stem cell transport and storage device with good stability according to claim 1, characterized in that: The lower locking block (9) and the upper locking block (15) are both trapezoidal integrated structures, and their shape and size are adapted to the trapezoidal groove (8). The surface of the trapezoidal groove (8) has two semi-circular grooves, and their shape and size are adapted to the lower rubber block (10) and the upper rubber block (16).

3. The stem cell transport and storage device with good stability according to claim 1, characterized in that: The upper pressure frame (14) has a circular through groove on its surface, the shape and size of which are adapted to the placement groove (12).

4. The stem cell transport and storage device with good stability according to claim 1, characterized in that: The surface of the transfer box (1) is connected to the mounting box (17), the inner wall surface of the mounting box (17) is connected to the fixing plate (18), the surface of the fixing plate (18) is threaded to the screw (19), and the surface of the screw (19) is threaded to the wing nut (20).

5. The stem cell transport and storage device with good stability according to claim 4, characterized in that: The bottom surface of the wing nut (20) abuts against the top of the fixed plate (18), the bottom surface of the screw (19) is connected to the moving plate (21), the bottom surface of the moving plate (21) is equipped with universal rollers (22), and the inner wall of the mounting box (17) is slidably sleeved with the moving plate (21).

6. The stem cell transport and storage device with good stability according to claim 5, characterized in that: The mounting box (17) has a rectangular through groove on its surface, the shape and size of which are adapted to the moving plate (21).

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