A kit for hpv pseudovirus packaging

Abstract

The utility model relates to the field of biotechnology especially, and one kind is reagent kit for HPV pseudo virus packing, in view of the problem that the reagent kit in the prior art lacks zoning function, present and propose the following scheme, it includes cylindrical storage box, and the inside storage box is cooperated with coaxial fixed column through three equidistance set baffle, and is divided into cold storage area, freezing area and normal temperature area, the top of fixed column is equipped with the sealing mechanism for covering the opening of storage box top, the sealing mechanism includes the connecting column fixed in the top of fixed column, the sealing cover of rotation sleeve connection in the outer periphery of connecting column and for covering the top of cold storage area and freezing area and the movable cover for covering the top of normal temperature area installed in the outer periphery of connecting column, the utility model realizes the zoning storage of different preservation condition reagent, guarantees reagent activity, reduces temperature fluctuation through the design of sealing mechanism simultaneously, convenient operation, applicable to the stable storage and use of reagent in HPV pseudo virus packing experiment.

Description

Technical Field

[0001] This invention relates to the field of biotechnology, and in particular to a reagent kit for packaging HPV pseudoviruses. Background Technology

[0002] In HPV pseudovirus packaging experiments, reagent storage conditions directly affect the accuracy and reproducibility of experimental results. Currently, most reagent kits have a single-chamber structure and lack corresponding compartmentalization, making it impossible to simultaneously meet the requirements for frozen, refrigerated, and room-temperature storage. Researchers need to prepare multiple independent storage containers, which not only takes up space but also easily leads to reagent confusion and increases the risk of operational errors.

[0003] Furthermore, traditional reagent kits typically have a one-piece cap design, requiring the kit to be fully opened to access any part of the reagent, which further exacerbates temperature fluctuations. Therefore, this paper proposes a reagent kit for packaging HPV pseudoviruses. Utility Model Content

[0004] This invention proposes a reagent kit for packaging HPV pseudoviruses, which solves the problem of existing reagent kits lacking partitioning functionality.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A kit for packaging HPV pseudoviruses includes a cylindrical storage box. Inside the storage box, there is a fixed column coaxially arranged therewith. Three partitions are fixed between the outer periphery of the fixed column and the inner ring of the storage box, so as to divide the inside of the storage box into a refrigeration zone, a freezing zone and a room temperature zone in sequence.

[0007] The top of the fixed column is equipped with a sealing mechanism for covering the top opening of the storage box. The sealing mechanism includes a connecting column fixed to the top of the fixed column, a sealing cover rotatably sleeved on the outer periphery of the connecting column for covering the top of the refrigeration and freezing zones, and a movable cover installed on the outer periphery of the connecting column for covering the top of the room temperature zone.

[0008] One end of the movable cover is fixed with an installation ring that is movably sleeved on the outer periphery of the connecting column. After the installation ring moves along the axial direction of the connecting column, it rotates to the top of the sealing cover to open the top of the room temperature zone.

[0009] Once the movable cover is rotated to the top of the sealing cover, the sealing cover can be rotated to open the top of the refrigerator or freezer compartment.

[0010] The above technical solution sets up three partitions inside the storage box to achieve partitioned storage of reagents under different storage conditions, ensuring reagent activity. At the same time, the design of the sealing mechanism reduces temperature fluctuations and is easy to operate. It is suitable for stable storage and retrieval of reagents in HPV pseudovirus packaging experiments.

[0011] As a further improvement to the above solution, the outer surface of the partition is provided with a heat insulation layer with a thickness of 1mm to 2mm, and the heat insulation layer material is aerogel insulation felt or flexible rubber and plastic insulation cotton.

[0012] Through the above technical solutions, the heat insulation layer can effectively block the heat transfer between zones.

[0013] As a further improvement to the above solution, the inner rings on both sides of the mounting ring are provided with limiting grooves, and the outer walls on both sides of the connecting column are fixed with limiting blocks, which are engaged in the limiting grooves after the movable cover covers the room temperature zone to restrict the rotation of the movable cover.

[0014] The above technical solution ensures that the movable cover rotates even when not in operation.

[0015] As a further improvement to the above solution, the bottom surfaces of the movable cover are fixed with locking strips arranged along the length of the partition. After the movable cover covers the top of the room temperature zone, the locking strips abut against the inner side of the two partitions located in the room temperature zone to restrict the rotation of the movable cover and the sealing cover.

[0016] The above technical solution further prevents the movable cover from rotating after it is closed.

[0017] As a further improvement to the above solution, the top surface of the sealing cover has two slots for engaging the locking strip.

[0018] With the above technical solution, when the movable cover is rotated to the top of the sealing cover, the locking strip can be accurately embedded in the locking groove to form a detachable fixation. This not only prevents the movable cover from slipping off during the rotation of the sealing cover, but also allows the sealing cover to be rotated by moving the movable cover, thus improving the ease of operation.

[0019] As a further improvement to the above solution, a positioning block is fixed to the top of the connecting column to prevent the mounting ring from falling off its outer periphery. A spring is also movably sleeved on the outer periphery of the connecting column. The bottom of the spring is fixedly connected to the top surface of the mounting ring, and the top of the spring is fixedly connected to the bottom surface of the positioning block.

[0020] By using the above technical solution, the resistance to the upward movement of the movable cover is increased, thereby preventing the movable cover from easily becoming loose.

[0021] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0022] 1. By setting up three partitions to divide the interior of the storage box into a refrigerated zone, a frozen zone, and a room temperature zone, the optimal storage conditions are provided for reagents with different properties, effectively preventing reagents from becoming inactive due to improper storage, and improving the stability of the reagents and the shelf life of the kit.

[0023] 2. By setting a sealing mechanism, the sealing cover can be freely rotated only after the movable cover is opened. This not only facilitates the retrieval and placement of reagents in the refrigeration or freezing compartments, but also keeps the freezing compartment closed when the refrigeration compartment is opened and the refrigeration compartment closed when the freezing compartment is opened, thus avoiding temperature changes in other areas when retrieving or placing reagents.

[0024] 3. The locking strip not only locks itself to the sealing cover after the movable cover is closed, but also allows the movable cover to lock onto the top of the sealing cover after the locking strip is inserted into the slot, making it convenient for staff to rotate the sealing cover by moving the edge of the movable cover. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the structure of this utility model;

[0026] Figure 2 This is an exploded view of the present invention;

[0027] Figure 3 for Figure 2 Enlarged view of point A in the middle;

[0028] Figure 4 A schematic diagram showing the structure when the movable cover engages with the top surface of the sealing cover;

[0029] Figure 5 This is a schematic diagram of the internal structure of the storage box;

[0030] Figure 6 A schematic diagram of the structure of the bottom surface of the movable cover.

[0031] Explanation of key symbols:

[0032] 1. Storage box; 2. Sealing cover; 3. Slot; 4. Movable cover; 5. Positioning block; 6. Locking strip; 7. Connecting post; 8. Partition; 9. Mounting ring; 10. Limiting groove; 11. Limiting block; 12. Refrigeration compartment; 13. Freezing compartment; 14. Room temperature compartment; 15. Fixing post; 16. Spring. Detailed Implementation

[0033] The present invention will be further described below with reference to the accompanying drawings and specific embodiments. It should be noted that, without conflict, the various embodiments or technical features described below can be arbitrarily combined to form new embodiments.

[0034] Example 1:

[0035] Please combine Figure 1 - Figure 6 This embodiment of an HPV pseudovirus packaging kit includes a cylindrical storage box 1, which is injection molded from food-grade PP material and has a smooth inner wall.

[0036] The storage box 1 has a fixed post 15 that is coaxially arranged inside it. The fixed post 15 is integrally formed with the storage box 1 and has the same height as the storage box 1.

[0037] Three equally spaced partitions 8 are fixed between the outer periphery of the fixed column 15 and the inner ring of the storage box 1 to divide the interior of the storage box 1 into three fan-shaped areas, namely the refrigeration area 12, the freezing area 13 and the room temperature area 14. The partitions 8 are made of ABS material.

[0038] A sealing mechanism for covering the top opening of the storage box 1 is installed on the top of the fixed column 15. The sealing mechanism includes a connecting column 7 fixed to the top of the fixed column 15, a sealing cover 2 rotatably sleeved on the outer periphery of the connecting column 7 for covering the top of the refrigeration zone 12 and the freezing zone 13, and a movable cover 4 installed on the outer periphery of the connecting column 7 for covering the top of the ambient temperature zone 14. Both the sealing cover 2 and the movable cover 4 are fan-shaped structures with the same diameter as the storage box 1. The covering angle of the sealing cover 2 is 240°, and the sealing angle of the movable cover 4 is 120°.

[0039] One end of the movable cover 4 is fixed with an installation ring 9 that is movably sleeved on the outer periphery of the connecting column 7. After the installation ring 9 moves along the axial direction of the connecting column 7 and rotates to the top of the sealing cover 2, the top of the room temperature zone 14 is opened. The movable cover 4 is used to seal the room temperature zone 14. After the movable cover 4 is opened, it is rotated to the top of the sealing cover 2 to keep the room temperature zone 14 open. Furthermore, the movable cover 4 will not obstruct the rotation of the sealing cover 2.

[0040] After the movable cover 4 is rotated to the top of the sealing cover 2, the sealing cover 2 can be rotated to open the top of the refrigerator compartment 12 or the freezer compartment 13. The sealing cover 2 can cover the top of the refrigerator compartment 12 and the freezer compartment 13, and when either compartment (refrigerator compartment 12 or freezer compartment 13) is opened, the other compartment remains sealed, thereby minimizing the flow of hot and cold air.

[0041] In this embodiment, limiting grooves 10 are provided on both inner rings of the mounting ring 9, and limiting blocks 11 are fixed on both outer walls of the connecting column 7. After the movable cover 4 covers the room temperature zone 14, it is engaged in the limiting grooves 10 to restrict the rotation of the movable cover 4. After the movable cover 4 covers the top of the room temperature zone 14, the limiting blocks 11 are engaged in the limiting grooves 10, so that the movable cover 4 will not rotate when closed, thus achieving the purpose of conveniently locking the movable cover 4 and the sealing cover 2. After the movable cover 4 is moved upward to above the sealing cover 2, the limiting blocks 11 disengage from the limiting grooves 10. Then, the movable cover 4 can be rotated to be directly above the sealing cover 2 and fall on the sealing cover 2, so as not to affect the rotation of the sealing cover 2.

[0042] In this embodiment, a positioning block 5 is fixed to the top of the connecting post 7 to prevent the mounting ring 9 from falling off its outer periphery. A spring 16 is also movably sleeved on the outer periphery of the connecting post 7. The bottom of the spring 16 is fixed to the top surface of the mounting ring 9, and the top of the spring 16 is fixed to the bottom surface of the positioning block 5. The setting of the spring 16 ensures that the movable cover 4 will not easily open when closed without the action of external force, thereby ensuring the stability of the entire sealing mechanism.

[0043] The implementation principle of this embodiment is as follows: the partitioning effect is achieved by setting up three partitions 8, so that reagents with different temperature requirements can be stored in different partitions. By placing ice packs in the refrigeration zone 12 or the freezing zone 13, the cooling effect is achieved.

[0044] The sealing mechanism is designed to allow for independent opening of a single zone. The movable cover 4 can be opened separately to open the room temperature zone. After rotating the movable cover 4 to the top of the sealing cover 2, the refrigeration zone 12 or the freezer zone 13 can be opened separately without affecting the other zone by rotating the sealing cover 2 in different directions.

[0045] Example 2:

[0046] Combination Figure 5 Based on Example 1, this embodiment is further improved in that: the outer surface of the partition 8 is provided with a heat insulation layer with a thickness of 1mm to 2mm, and the heat insulation layer material is either aerogel insulation felt or flexible rubber and plastic insulation cotton. The setting of the heat insulation layer can effectively improve the heat insulation effect and effectively reduce the heat transfer between the partitions, thereby maintaining the temperature stability in each partition.

[0047] Example 3:

[0048] Combination Figure 1 , Figure 2 , Figure 4 and Figure 6This embodiment, based on Embodiments 1 and 2, further improves upon the following: Both sides of the bottom surface of the movable cover 4 are fixed with locking strips 6 arranged along the length of the partitions 8. After the movable cover 4 covers the top of the room temperature zone 14, the locking strips 6 abut against the inner sides of the two partitions 8 located in the room temperature zone 14, thus restricting the rotation of the movable cover 4 and the sealing cover 2. The top surface of the sealing cover 2 has two slots 3 for engaging the locking strips 6. The locking strips 6 not only engage with the inner sides of the two partitions 8 after the movable cover 4 covers the top of the room temperature zone, further preventing the movable cover 4 from rotating after being closed, but also allow the locking strips 6 to be engaged in the slots 3 after the movable cover 4 is rotated to the top of the sealing cover 2. This allows the sealing cover 2 to rotate by moving the edge of the movable cover 4, while also preventing the movable cover 4 from rotating during the rotation of the sealing cover 2. The spring 16 also provides a downward force to the movable cover 14, preventing the locking strips 6 from easily exiting the slots 3.

[0049] The above embodiments are merely preferred embodiments of this utility model and should not be construed as limiting the scope of protection of this utility model. Any non-substantial changes and substitutions made by those skilled in the art based on this utility model shall fall within the scope of protection claimed by this utility model.

Claims

1. A reagent kit for packaging HPV pseudoviruses, characterized in that, The storage box includes a cylindrical storage box, with a fixed column coaxially arranged inside the storage box. Three partitions are fixed between the outer periphery of the fixed column and the inner ring of the storage box to divide the interior of the storage box into a refrigeration zone, a freezing zone and a room temperature zone in sequence. The top of the fixed column is equipped with a sealing mechanism for covering the top opening of the storage box. The sealing mechanism includes a connecting column fixed to the top of the fixed column, a sealing cover rotatably sleeved on the outer periphery of the connecting column for covering the top of the refrigeration and freezing zones, and a movable cover installed on the outer periphery of the connecting column for covering the top of the room temperature zone. One end of the movable cover is fixed with an installation ring that is movably sleeved on the outer periphery of the connecting column. After the installation ring moves along the axial direction of the connecting column, it rotates to the top of the sealing cover to open the top of the room temperature zone. Once the movable cover is rotated to the top of the sealing cover, the sealing cover can be rotated to open the top of the refrigerator or freezer compartment.

2. The HPV pseudovirus packaging kit according to claim 1, characterized in that, The outer surface of each partition is provided with a heat insulation layer with a thickness of 1mm to 2mm, and the heat insulation layer material is either aerogel insulation felt or flexible rubber and plastic insulation cotton.

3. The HPV pseudovirus packaging kit according to claim 1, characterized in that, The inner rings on both sides of the mounting ring are provided with limiting grooves, and the outer walls on both sides of the connecting column are fixed with limiting blocks, which are engaged in the limiting grooves after the movable cover covers the room temperature area to restrict the rotation of the movable cover.

4. The HPV pseudovirus packaging kit according to claim 1, characterized in that, Both sides of the bottom surface of the movable cover are fixed with locking strips arranged along the length of the partition. After the movable cover covers the top of the room temperature zone, the locking strips abut against the inner side of the two partitions located in the room temperature zone to restrict the rotation of the movable cover and the sealing cover.

5. The HPV pseudovirus packaging kit according to claim 1, characterized in that, The top surface of the sealing cover has two slots for engaging the locking strip.

6. The HPV pseudovirus packaging kit according to claim 1, characterized in that, The top of the connecting column is fixed with a positioning block to prevent the mounting ring from falling off its outer periphery. A spring is also movably sleeved on the outer periphery of the connecting column. The bottom of the spring is fixed to the top surface of the mounting ring, and the top of the spring is fixed to the bottom surface of the positioning block.

Images