A cellular antibody conjugation assay device
Patent Information
- Application Number
- CN202522336803.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-04
- Publication Date
- 2026-10-16
- Estimated Expiration
- 2035-11-04
AI Technical Summary
[0005]有鉴于此，本实用新型提出一种细胞抗体偶联检验装置，应用于细胞检验辅助设备的技术领域，解决现有存在的透明托盘容易发生偏移、检测数据不准确和防尘效果差的技术问题
1、本实用新型提到一种细胞抗体偶联检验装置，通过透明托盘与第一安装槽和限位块与限位槽的配合，避免透明托盘在安装后出现左右偏移、前后晃动的情况，确保透明托盘始终处于预设的工作位置，为后续检测组件的精准检测提供稳定的承载基础，通过两个拿取槽的设计，为工作人员提供了便捷的施力空间，工作人员可将手指伸入拿取槽内，轻松扣住透明托盘边缘，快速将透明托盘从第一安装槽中取出，无需借助额外工具，提升样本更换、透明托盘清洁的效率，采用橡胶材质制成的防滑垫具有出色的防滑性能，能增大机座与放置台面之间的摩擦力，在检测时，使其不易发生晃动，稳定性较高，通过四个防滑垫的设计，进一步提升整体在使用时的稳定性。
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Figure CN224861479U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the technical field of cell testing auxiliary equipment, specifically relating to a cell antibody conjugate testing device. Background Technology
[0002] The cell antibody-coupled assay (CCA) device is an integrated testing device based on the principle of antigen-antibody specific binding, combining cell capture, antibody-coupled reaction, and signal detection. It is widely used in clinical diagnosis, biomedical research, and other fields. Its core workflow involves first capturing target cells through a microfluidic chip or reaction chamber within the device, then adding specific antibodies to allow them to precisely bind to cell surface antigens. Finally, an optical detection module (such as a fluorescence imager) or an electrochemical sensor converts the antigen-antibody binding signal into quantifiable data, enabling qualitative and quantitative analysis of the target cells. This device has the advantages of high sensitivity, strong specificity, and fast detection speed, and is widely used in scenarios such as tumor cell detection and pathogen screening, providing key technical support for early disease diagnosis and efficacy evaluation.
[0003] In such devices, transparent trays are typically used to hold cell samples. Due to their transparency, they can work with optical detection modules to acquire signals, thus ensuring the accuracy of the detection. However, in existing technologies, although transparent trays can be placed for convenient subsequent detection, no limiting structure for the transparent trays is designed. When the corresponding moving frame in the device moves with the transparent tray, the transparent tray may shift, affecting the detection data. Furthermore, no dustproof structure is designed, and after detection, the surface of the moving frame is easily contaminated by dust, affecting the data of the next detection. This results in poor practicality and makes it difficult to promote its use.
[0004] To address these issues, we propose a cell antibody conjugate assay device that solves problems such as easy displacement of the transparent tray, inaccurate test data, and poor dust protection during use. Utility Model Content
[0005] In view of this, the present invention proposes a cell antibody conjugate testing device, which is applied to the technical field of cell testing auxiliary equipment, and solves the existing technical problems of transparent trays being prone to displacement, inaccurate test data, and poor dustproof effect.
[0006] To achieve the above-mentioned technical objectives, the specific technical solution adopted by this utility model is as follows: A cell antibody conjugate testing device includes a base, a detection component, and a movable frame. The outer wall of the movable frame has a first mounting groove and a retrieval groove. A limit block is fixedly installed on the inner wall of the first mounting groove. A transparent tray is provided on the outer wall of the movable frame. A limit groove is provided on the outer wall of the transparent tray. A dust cover is provided on the outer wall of the movable frame. An insert and a buckle are fixedly installed on the side of the dust cover near the movable frame. A second mounting groove is provided on the outer wall of the insert. A sealing ring is provided on the inner wall of the second mounting groove. A slot and a locking groove are provided on the side of the movable frame near the dust cover.
[0007] Furthermore, an anti-slip pad is provided on the side of the base away from the detection components. The anti-slip pad is made of rubber and there are four identical anti-slip pads. The four anti-slip pads are symmetrically distributed at the four corners of the bottom of the base, which can increase the friction between the base and the table surface.
[0008] Furthermore, the transparent tray is adapted to the first mounting slot, and the limiting block is adapted to the limiting slot. The operator places the transparent tray into the first mounting slot and inserts the limiting block into the limiting slot to prevent the transparent tray from shifting left and right or wobbling back and forth after installation.
[0009] Furthermore, the retrieval slot is connected to the first mounting slot. There are two retrieval slots, which are symmetrically distributed about the center line of the transparent tray. The design of the two retrieval slots provides workers with convenient space to apply force.
[0010] Furthermore, the plug and slot are installed by plugging in, and the buckle and slot are compatible. When not in use, the operator inserts the plug into the slot. When the buckle comes into contact with the moving frame, the buckle deforms. When the plug is fully submerged in the slot, the buckle returns to its original shape, so that the buckle is engaged in the slot.
[0011] Furthermore, the sealing rings are made of rubber, and there are three identical sealing rings distributed at equal intervals. This effectively prevents external dust and fine impurities from entering the dust cover through the gaps, greatly improving the dustproof effect and reducing inspection errors caused by dust contamination.
[0012] Furthermore, the dust cover is made of acrylic material, which has high transparency.
[0013] By adopting the above technical solution, this utility model can also bring the following beneficial effects: 1. This utility model discloses a cell antibody conjugate testing device. Through the cooperation of a transparent tray with a first mounting groove and a limiting block with the limiting groove, it prevents the transparent tray from shifting left or right or wobbling back and forth after installation, ensuring that the transparent tray is always in the preset working position. This provides a stable support foundation for the accurate detection of subsequent testing components. The design of two retrieval slots provides convenient space for operators to apply force. Operators can insert their fingers into the retrieval slots to easily grasp the edge of the transparent tray and quickly remove it from the first mounting groove without the need for additional tools, improving the efficiency of sample replacement and transparent tray cleaning. The anti-slip pads made of rubber have excellent anti-slip performance, increasing the friction between the base and the placement surface, making it less prone to shaking during testing and ensuring high stability. The design of four anti-slip pads further enhances the overall stability during use.
[0014] 2. This utility model discloses a cell antibody conjugation testing device. Through the cooperation of inserts and slots, and buckles and grooves, a dust cover can be quickly installed, facilitating rapid removal and installation before and after testing. The sealing ring, made of rubber, has good elasticity and sealing performance, effectively preventing external dust and fine impurities from entering the dust cover through gaps, significantly improving dust protection and reducing testing errors caused by dust contamination. The dust cover, made of acrylic, has high transparency, allowing staff to clearly observe whether there is contamination inside the first installation slot without disassembling the dust cover. The acrylic material also provides high hardness and impact resistance, making it less prone to breakage from collisions or drops, reducing the risk of damage and making it more suitable for frequently used laboratory environments. Attached Figure Description
[0015] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0016] Figure 1 This is a schematic diagram of the structure of a cell antibody conjugate testing device mentioned in this utility model; Figure 2 This is a schematic diagram of the connection structure between the detection component and the base in this embodiment; Figure 3 This is a schematic diagram showing the positional relationship between the dust cover and the sealing ring in this embodiment; Figure 4 For this embodiment Figure 3 A magnified structural diagram at point A; Figure 5This is a schematic diagram of the connection structure between the transparent tray and the limiting groove in this embodiment; In the diagram: 1. Base; 2. Detection component; 3. Anti-slip pad; 4. Movable frame; 5. First mounting slot; 6. Limiting block; 7. Pick-up slot; 8. Transparent tray; 9. Limiting slot; 10. Dust cover; 11. Insert block; 12. Second mounting slot; 13. Sealing ring; 14. Buckle; 15. Slot; 16. Slot. Detailed Implementation
[0017] The embodiments of this utility model will now be described in detail with reference to the accompanying drawings.
[0018] The following specific examples illustrate the implementation of this utility model. Those skilled in the art can easily understand other advantages and effects of this utility model from the content disclosed in this specification. Obviously, the described embodiments are only a part of the embodiments of this utility model, not all of them. This utility model can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of this utility model. It should be noted that, in the absence of conflict, the following embodiments and features in the embodiments can be combined with each other. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.
[0019] It should be noted that various aspects of embodiments within the scope of the appended claims are described below. It will be apparent that the aspects described herein can be embodied in a wide variety of forms, and any particular structure and / or function described herein is merely illustrative. Based on this invention, those skilled in the art will understand that one aspect described herein can be implemented independently of any other aspect, and two or more of these aspects can be combined in various ways. For example, any number of aspects set forth herein can be used to implement the device and / or practice the method. Additionally, this device and / or method can be implemented using other structures and / or functionalities besides one or more of the aspects set forth herein.
[0020] It should also be noted that the illustrations provided in the following embodiments are only schematic representations of the basic concept of the present invention. The drawings only show the components related to the present invention and are not drawn according to the actual number, shape and size of the components. In actual implementation, the form, quantity and proportion of each component can be arbitrarily changed, and the layout of the components may also be more complex.
[0021] Furthermore, specific details are provided in the following description to facilitate a thorough understanding of the examples. However, those skilled in the art will understand that the described aspects can be practiced without these specific details. Example 1
[0022] like Figures 1 to 5 As shown, the present invention provides a cell antibody conjugate testing device, including a base 1, a detection component 2, and a movable frame 4. The outer wall of the movable frame 4 is provided with a first mounting groove 5 and a retrieval groove 7. A limiting block 6 is fixedly installed on the inner wall of the first mounting groove 5. A transparent tray 8 is provided on the outer wall of the movable frame 4. A limiting groove 9 is provided on the outer wall of the transparent tray 8. A dust cover 10 is provided on the outer wall of the movable frame 4. An insert 11 and a buckle 14 are fixedly installed on the side of the dust cover 10 near the movable frame 4. A second mounting groove 12 is provided on the outer wall of the insert 11. A sealing ring 13 is provided on the inner wall of the second mounting groove 12. A slot 15 and a card slot 16 are provided on the side of the movable frame 4 near the dust cover 10.
[0023] An anti-slip pad 3 is provided on the side of the base 1 away from the detection component 2. The anti-slip pad 3 is made of rubber, and four identical anti-slip pads 3 are symmetrically distributed at the four corners of the bottom of the base 1. The advantage is that the anti-slip pad 3, made of rubber, has excellent anti-slip performance, which increases the friction between the base 1 and the table surface, making it less prone to shaking during detection and providing high stability. The design of four anti-slip pads 3 further enhances the overall stability during use.
[0024] The transparent tray 8 is adapted to the first mounting slot 5, and the limiting block 6 is adapted to the limiting slot 9. The advantage is that when the operator places the transparent tray 8 into the first mounting slot 5 and simultaneously inserts the limiting block 6 into the limiting slot 9, it prevents the transparent tray 8 from shifting left or right or wobbling back and forth after installation, ensuring that the transparent tray 8 is always in the preset working position, providing a stable bearing foundation for the accurate testing of the subsequent testing component 2. The retrieval slot 7 communicates with the first mounting slot 5. There are two retrieval slots 7, both with identical structures, symmetrically distributed about the center line of the transparent tray 8. The advantage is that the design of the two retrieval slots 7 provides convenient leverage space for the operator. The operator can insert their fingers into the retrieval slot 7 to easily grasp the edge of the transparent tray 8 and quickly remove it from the first mounting slot 5 without the need for additional tools, improving the efficiency of sample replacement and cleaning of the transparent tray 8.
[0025] The insert 11 and the slot 15 are installed by plugging in. The buckle 14 is compatible with the slot 16. The advantage is that when not in use, the operator inserts the insert 11 into the slot 15. When the buckle 14 comes into contact with the moving frame 4, the buckle 14 deforms. When the insert 11 is completely submerged in the slot 15, the buckle 14 returns to its original shape, so that the buckle 14 is locked into the slot 16. This allows for the quick installation of the dust cover 10, which is convenient for quick removal of the dust cover 10 before inspection and quick installation of the dust cover 10 after inspection.
[0026] The sealing ring 13 is made of rubber, and three identical sealing rings 13 are evenly spaced. The advantage is that the rubber sealing ring 13 has good elasticity and sealing performance, effectively preventing external dust and fine impurities from entering the interior of the dust cover 10 through gaps, significantly improving dust protection and reducing inspection errors caused by dust contamination. The dust cover 10 is made of acrylic. The advantage is that the acrylic dust cover 10 has high transparency, allowing personnel to clearly observe whether the interior of the first mounting groove 5 is contaminated without disassembling the dust cover 10. The high hardness and impact resistance of the acrylic dust cover 10 make it less prone to breakage from collisions or drops, reducing the risk of damage and making it more suitable for frequently used laboratory environments.
[0027] In use, the operator places the transparent tray 8 into the first mounting slot 5 and simultaneously inserts the limiting block 6 into the limiting slot 9 to prevent the transparent tray 8 from shifting left or right or wobbling back and forth after installation. This ensures that the transparent tray 8 remains in the preset working position, providing a stable support for the subsequent accurate testing of the testing component 2. During use, the design of two retrieval slots 7 provides convenient space for the operator to apply force. The operator can insert their fingers into the retrieval slots 7 to easily grip the edge of the transparent tray 8 and quickly remove it from the first mounting slot 5 without the need for assistance. Additional tools improve the efficiency of sample replacement and cleaning of the transparent tray 8. When not in use, the operator inserts the insert 11 into the slot 15. When the latch 14 contacts the moving frame 4, the latch 14 deforms. When the insert 11 is fully submerged in the slot 15, the latch 14 returns to its original shape, allowing the latch 14 to engage with the slot 16. This enables the quick installation of the dust cover 10, facilitating its rapid removal before inspection and its quick installation after inspection. In summary, this utility model has the advantages of simple structure, convenient operation, good dustproof effect, transparent tray that is not easily shifted, and accurate test data.
[0028] The above description is merely a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the scope of the claims.
Claims
1. A cell antibody-coupled assay device, comprising a base (1), a detection assembly (2), and a movable frame (4), characterized in that: The outer wall of the movable frame (4) is provided with a first mounting groove (5) and a retrieval groove (7). A limiting block (6) is fixedly installed on the inner wall of the first mounting groove (5). The outer wall of the movable frame (4) is provided with a transparent tray (8). A limiting groove (9) is opened on the outer wall of the transparent tray (8). The outer wall of the movable frame (4) is provided with a dust cover (10). A plug (11) and a buckle (14) are fixedly installed on the side of the dust cover (10) near the movable frame (4). The outer wall of the plug (11) is provided with a second mounting groove (12). A sealing ring (13) is provided on the inner wall of the second mounting groove (12). The side of the movable frame (4) near the dust cover (10) is provided with a slot (15) and a card slot (16).
2. The cell antibody-coupled assay device according to claim 1, characterized in that: The base (1) is provided with an anti-slip pad (3) on the side away from the detection component (2). The anti-slip pad (3) is made of rubber. There are four identical anti-slip pads (3), which are symmetrically distributed at the four corners of the bottom of the base (1).
3. The cell antibody-coupled assay device according to claim 2, characterized in that: The transparent tray (8) is adapted to the first mounting groove (5), and the limiting block (6) is adapted to the limiting groove (9).
4. The cell antibody-coupled assay device according to claim 3, characterized in that: The take-up slot (7) is connected to the first mounting slot (5). There are two take-up slots (7), and the two take-up slots (7) are symmetrically distributed about the center line of the transparent tray (8).
5. The cell antibody-coupled assay device according to claim 4, characterized in that: The plug (11) and the slot (15) are plugged in and installed together, and the buckle (14) is adapted to the slot (16).
6. The cell antibody-coupled assay device according to claim 5, characterized in that: The sealing ring (13) is made of rubber. There are three identical sealing rings (13), and the three sealing rings (13) are distributed at equal intervals.