Radio frequency-optical power tumor killing treatment control circuit and system

Abstract

The application relates to the technical field of biomedicine and discloses a radio frequency-optical power tumor killing treatment control circuit and system. The control circuit comprises a power module, a radio frequency generating module, a radio frequency output electrode, an LED light source control module, a photosensitizer injection pump control module, a main control system and a display module; the main control system is electrically connected with the radio frequency generating module, the LED light source control module, the photosensitizer injection pump control module and the display module respectively; the power module is electrically connected with the radio frequency generating module, the LED light source control module and the photosensitizer injection pump control module respectively; and the radio frequency generating module, the LED light source control module and the photosensitizer injection pump control module are electrically connected with the radio frequency output electrode respectively. Through real-time heating of tumor cells by radio frequency energy, ablation treatment is carried out, an LED light source is integrated, photosensitizers are synchronously released, the synergistic effect of radio frequency ablation and photodynamic effect is realized, the clinical effect of radio frequency ablation and photodynamic effect "1+1>=2" is achieved, and the effect and precision of tumor treatment are improved.

Description

Technical Field

[0001] This application relates to the field of biomedical technology, and in particular to a radiofrequency-photodynamic tumor killing therapy control circuit and system. Background Technology

[0002] Radio frequency (RF) refers to radio frequency, and its main effect in living organisms is thermal. When the frequency of radio frequency current reaches a certain value (>100kHz), it can induce the movement of charged ions within tissues, thereby generating frictional heat. Based on this principle, radiofrequency ablation technology has emerged. This technology, guided by imaging techniques (such as ultrasound, CT, or MRI), places electrodes directly into tumor cells. Radiofrequency energy induces a resistive electrothermal effect in the local tumor tissue, leading to high-temperature dehydration and ultimately achieving coagulation and inactivation of the tumor. In recent years, radiofrequency ablation has gained popularity and recognition among scholars due to its unique advantages and has been widely applied in the treatment of tumors in tissues such as the lungs, breasts, liver, and kidneys.

[0003] However, existing radiofrequency ablation technology has certain limitations. Its ablation range is usually only about 3 centimeters, and in clinical applications, the inactivation boundary near the tumor edge is not clear enough, which to some extent limits its therapeutic effect and application scope. Utility Model Content

[0004] The technical problem to be solved by this application is to provide a radiofrequency-photodynamic tumor killing therapy control circuit and system, which uses radiofrequency energy to heat tumor cells in real time for ablation therapy, and integrates an LED light source to release photosensitizer simultaneously, so as to achieve the synergistic effect of radiofrequency ablation and photodynamic effect, thereby achieving the clinical effect of "1+1≥2" of radiofrequency ablation and photodynamic effect, and further improving the efficacy and precision of tumor treatment.

[0005] In a first aspect, this application provides a radiofrequency-photodynamic tumor killing therapy control circuit, including a power supply module, a radiofrequency generation module, a radiofrequency output electrode, an LED light source control module, a photosensitizer injection pump control module, a main control system, and a display module; the main control system is electrically connected to the radiofrequency generation module, the LED light source control module, the photosensitizer injection pump control module, and the display module respectively; the power supply module is electrically connected to the radiofrequency generation module, the LED light source control module, and the photosensitizer injection pump control module respectively; the radiofrequency generation module, the LED light source control module, and the photosensitizer injection pump control module are electrically connected to the radiofrequency output electrode respectively.

[0006] Preferably, the radio frequency generation module includes a first switch, a second switch, and a transformer. The gate of the first switch and the gate of the second switch are electrically connected to the main control system, respectively. The drain of the first switch and the drain of the second switch are electrically connected to the input terminal of the transformer, respectively. The source of the first switch and the source of the second switch are grounded, respectively. The output terminal of the transformer is electrically connected to the radio frequency output electrode, and the power supply module is electrically connected to the tap of the transformer.

[0007] Preferably, the radio frequency generation module further includes a first capacitor, the two ends of which are electrically connected to the transformer and the radio frequency output electrode, respectively.

[0008] Preferably, the control circuit further includes a first inductor, the two ends of which are electrically connected to the power module and the taps of the transformer, respectively.

[0009] Preferably, the LED light source control module includes an LED light source control unit and an LED light source. The two ends of the LED light source control unit are electrically connected to the main control system and one end of the LED light source, respectively. The LED light source control unit is also electrically connected to the power supply module, and the other end of the LED light source is electrically connected to the radio frequency output electrode.

[0010] Preferably, the photosensitizer injection pump control module includes a photosensitizer injection pump control unit and a photosensitizer injection pump. The two ends of the photosensitizer injection pump control unit are electrically connected to the main control system and one end of the photosensitizer injection pump, respectively. The photosensitizer injection pump control unit is electrically connected to the power supply module, and the other end of the photosensitizer injection pump is electrically connected to the radio frequency output electrode.

[0011] Preferably, the control circuit further includes a first start-stop control unit and a second start-stop control unit. The two ends of the first start-stop control unit are electrically connected to the main control system and the LED light source control module, respectively, and the two ends of the second start-stop control unit are electrically connected to the main control system and the photosensitizer injection pump control module, respectively.

[0012] Secondly, Embodiment 2 of this application provides a radiofrequency-photodynamic tumor killing therapy system, which utilizes the control circuit described in the first aspect. The system includes a radiofrequency generator, a radiofrequency output negative electrode plate, a radiofrequency output electrode, an LED light source control unit, a photosensitizer injection pump control unit, a main control system, and a display module. The main control system is communicatively connected to the radiofrequency generator, the LED light source control unit, the photosensitizer injection pump control unit, and the display module. The radiofrequency generator controls the radiofrequency output negative electrode plate and the radiofrequency output electrode to form a radiofrequency output circuit. The radiofrequency output electrode integrates an LED light source and a photosensitizer injection channel. The radiofrequency energy generated by the radiofrequency output electrode directly acts on the tumor tissue. The LED light source control unit controls the light source intensity of the LED light source, and the photosensitizer injection pump control unit controls the injection flow rate of the photosensitizer in the photosensitizer injection channel.

[0013] Preferably, the radio frequency output electrode has a radio frequency needle for puncturing into tumor tissue, the tip of the radio frequency needle is provided with the LED light source, the photosensitizer injection channel is formed inside the tube of the radio frequency needle, and the tube wall of the radio frequency needle has a photosensitizer injection hole.

[0014] Preferably, the radio frequency output negative electrode plate is made of a conductive material, and the radio frequency output negative electrode plate has an adhesive layer on its exterior.

[0015] Compared with the prior art, this application includes at least one of the following beneficial technical effects:

[0016] The main control system adjusts the output energy intensity and frequency through the radio frequency generation module, targeting the tumor tissue via the radio frequency output electrode. The high-frequency electromagnetic field generates heat to destroy cancer cell structures. The LED light source control module precisely matches the wavelength of the photosensitizer absorption peak, and combined with the photosensitizer injection pump control module, quantitatively delivers the photosensitizer. This generates reactive oxygen species (ROS) through a photochemical reaction, selectively killing tumor cells. The power supply module provides independent power to each module, ensuring stable energy output and reducing interference. This control circuit precisely regulates the output intensity and frequency of the radio frequency energy, as well as key parameters such as the wavelength and irradiation time of the photodynamic therapy light source, ensuring the synergistic effect of the two treatment methods. This efficiently and safely kills tumor cells, providing more precise and effective control for tumor treatment. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of this application, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a circuit diagram of the radiofrequency-photodynamic tumor killing therapy control circuit in an embodiment of this application.

[0019] Figure 2 This is a framework diagram of the radiofrequency-photodynamic tumor killing therapy control system in the embodiments of this application.

[0020] Figure 3 This is a schematic diagram of the overall structure of the radio frequency needle in the embodiments of this application.

[0021] Figure 4 This is a cross-sectional view of the radio frequency needle in an embodiment of this application.

[0022] Explanation of reference numerals in the attached diagram: Q1, first switch; Q2, second switch; Q3, third switch; L1, first inductor; L2, second inductor; L3, third inductor; L4, fourth inductor; C1, first capacitor; R1, first resistor; R2, second resistor; R3, third resistor; D, Zener diode; 1, needle tip; 2, LED light source; 3, needle tube; 4, insulating sleeve; 5, LED light source cable; 6, photosensitizer injection hole; 7, photosensitizer injection channel. Detailed Implementation

[0023] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0024] It should be understood that, when used in this specification and the appended claims, the terms "comprising" and "including" indicate the presence of the described features, integrals, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, integrals, steps, operations, elements, components and / or collections thereof.

[0025] It should also be understood that the terminology used in this application specification is for the purpose of describing particular embodiments only and is not intended to limit the application. As used in this application specification and the appended claims, the singular forms “a,” “an,” and “the” are intended to include the plural forms unless the context clearly indicates otherwise.

[0026] It should also be further understood that the term “and / or” as used in this application specification and the appended claims means any combination of one or more of the associated listed items and all possible combinations, and includes such combinations.

[0027] Please refer to Figure 1 and Figure 2 This application provides a radiofrequency-photodynamic tumor killing therapy control circuit, which can be applied to the operation control of a radiofrequency-photodynamic tumor killing therapy system.

[0028] The control circuit includes a power supply module, a radio frequency (RF) generator module, an RF output electrode, an LED light source control module, a photosensitizer injection pump control module, a main control system, and a display module. Specifically, the main control system is electrically connected to the RF generator module, the LED light source control module, the photosensitizer injection pump control module, and the display module; the power supply module is electrically connected to the RF generator module, the LED light source control module, and the photosensitizer injection pump control module; and the RF generator module, the LED light source control module, and the photosensitizer injection pump control module are electrically connected to the RF output electrode.

[0029] Here, the main control system adjusts the output energy intensity and frequency through the radio frequency generation module, targeting the tumor tissue via the radio frequency output electrode. The high-frequency electromagnetic field generates heat, destroying the cancer cell structure. The LED light source control module precisely matches the wavelength of the photosensitizer absorption peak, and combined with the photosensitizer injection pump control module, quantitatively delivers the photosensitizer. Through photochemical reactions, reactive oxygen species (ROS) are generated, selectively killing tumor cells. The power supply module provides independent power to each module, ensuring stable energy output and reducing interference. This control circuit precisely regulates the output intensity and frequency of the radio frequency energy, as well as key parameters such as the wavelength and irradiation time of the photodynamic therapy light source, ensuring the synergistic effect of the two treatment methods. This efficiently and safely kills tumor cells, providing more precise and effective control for tumor treatment.

[0030] In one specific embodiment, the radio frequency (RF) generation module includes a first switch Q1, a second switch Q2, and a transformer. The gates of the first switch Q1 and the second switch Q2 are electrically connected to the main control system, the drains of the first switch Q1 and the second switch Q2 are electrically connected to the input terminal of the transformer, the sources of the first switch Q1 and the second switch Q2 are grounded, the output terminal of the transformer is electrically connected to the RF output electrode, and the power supply module is electrically connected to the transformer taps.

[0031] The gates of the first switch Q1 and the second switch Q2 are connected to the main control system. The main control system can flexibly adjust the signal at the transformer input by controlling the on / off states of these two switches. Because the transformer output is connected to the radio frequency output electrode, the intensity and frequency of the radio frequency energy output to the tumor tissue can be changed. This allows for precise energy output adjustment based on the size, location, and type of the tumor, improving the targeting and effectiveness of the treatment. The sources of the first switch Q1 and the second switch Q2 are grounded, effectively preventing static electricity buildup or abnormal current in the circuit, ensuring the stable operation of the entire radio frequency generation module. Simultaneously, it prevents abnormal high voltage in the circuit from damaging the human body and equipment, enhancing safety during use.

[0032] The first switch Q1 and the second switch Q2 in the radiofrequency generation module are uniformly controlled by the main control system, realizing centralized management of the entire control circuit. The main control system can adjust the radiofrequency energy output in real time according to treatment needs and feedback information, enabling radiofrequency therapy and photodynamic therapy to work together better, improving the efficiency and safety of tumor killing.

[0033] The power module connects to the transformer's taps, providing a stable power supply. The transformer converts and adjusts the power supplied by the power module to meet the different voltage and current requirements of the radiofrequency output electrodes. A stable power supply is fundamental to ensuring the normal operation of the radiofrequency generator module, thereby ensuring continuous and stable radiofrequency therapy.

[0034] Furthermore, the transformer is composed of a second inductor L2, a third inductor L3 and a fourth inductor L4, and the end of the second inductor L2 connected to the third inductor L3 has a tap, the other end of the second inductor L2 is connected to the first switch Q1, the other end of the third inductor L3 is connected to the second switch Q2, and the fourth inductor L4 is connected to the radio frequency output electrode.

[0035] To address this, the second inductor L2 and the third inductor L3 are interconnected via taps to form a push-pull primary winding. When the main control system controls the first switch Q1 and the second switch Q2 to conduct alternately (e.g., when the first switch Q1 is on, the second switch Q2 is off, and vice versa), the second inductor L2 and the third inductor L3 will take turns serving as the "upper half-bridge" and "lower half-bridge" of the primary winding, generating bidirectional alternating magnetic flux in the transformer core. This transformer, through its push-pull primary winding and center-tapped structure, constructs an RF power link that combines "high-efficiency energy conversion, wide-range impedance matching, and low-noise output." It can achieve dual-ratio output through switching states, precisely matching the energy requirements of different tumor depths and sizes.

[0036] In one specific embodiment, the radio frequency (RF) generation module further includes a first capacitor C1, with its two ends electrically connected to a transformer and an RF output electrode, respectively. The first capacitor C1, the transformer, and the RF output electrode form an LC resonant circuit. By adjusting the capacitance value, the characteristic impedance of the RF system (e.g., a 50Ω standard impedance) can be matched, reducing signal reflection and energy loss. Through filtering, impedance matching, and surge suppression, the first capacitor C1 optimizes the quality of the RF signal and energy transmission efficiency, ensuring both the safety and stability of the treatment. Furthermore, by precisely controlling the thermal effect, it enhances the synergistic effect with photodynamic therapy, making it a key circuit component for achieving efficient tumor killing.

[0037] In one specific embodiment, the control circuit further includes a first inductor L1, with its two ends electrically connected to the power supply module and the transformer taps, respectively. The first inductor L1 constructs a dynamic energy bridge between the power supply and the transformer through a triple mechanism of "filtering-current stabilization-interference suppression," suitable for tumor treatment scenarios requiring long-term stable output, providing crucial support for the controllability of radiofrequency energy and system safety. Specifically, it ensures symmetrical operation of the push-pull circuit, avoiding core saturation and energy fluctuations; it suppresses transient impacts on the first switch Q1 and the second switch Q2, extending hardware lifespan; it meets the electromagnetic compatibility requirements of medical devices, ensuring safe clinical applications; and it optimizes energy transmission efficiency, ensuring continuous and precise radiofrequency treatment.

[0038] In one specific embodiment, the LED light source control module includes an LED light source control unit and an LED light source. The two ends of the LED light source control unit are electrically connected to the main control system and one end of the LED light source, respectively. The LED light source control unit is also electrically connected to a power supply module, and the other end of the LED light source is electrically connected to an RF output electrode.

[0039] The LED light source control unit is connected to the main control system. The main control system can send commands to the LED light source control unit based on factors such as the type, location, and size of the tumor, precisely adjusting parameters such as the LED light source's luminous intensity, illumination time, and emission frequency. For example, for tumor tissues with different sensitivities, the light intensity can be adjusted to achieve the best photochemical reaction effect; for tumors in deeper locations, the treatment effect can be enhanced by extending the illumination time or adjusting the emission frequency. The main control system can synchronously adjust the LED light source's operating parameters according to the progress and status of radiofrequency therapy, enabling better synergy between photodynamic therapy and radiofrequency therapy. For instance, after radiofrequency therapy causes initial thermal damage to the tumor tissue, timely adjustment of the LED light source parameters can initiate photodynamic therapy, utilizing reactive oxygen species to further kill tumor cells and improve the overall treatment efficiency.

[0040] In one specific embodiment, the photosensitizer injection pump control module includes a photosensitizer injection pump control unit and a photosensitizer injection pump. The two ends of the photosensitizer injection pump control unit are electrically connected to the main control system and one end of the photosensitizer injection pump, respectively. The photosensitizer injection pump control unit is also electrically connected to a power supply module, and the other end of the photosensitizer injection pump is electrically connected to an RF output electrode.

[0041] The photosensitizer infusion pump control unit receives instructions from the main control system (such as preset parameters like dosage, flow rate, and time in the treatment plan) and precisely controls the working status of the photosensitizer infusion pump. For example, the required photosensitizer dosage is calculated based on the tumor volume, and the infusion pump control unit adjusts the pump to infuse at a constant flow rate, avoiding manual operation errors. The main control system can dynamically adjust the photosensitizer infusion rate based on real-time treatment feedback (such as the temperature of radiofrequency therapy and the intensity of LED light illumination). For example, when radiofrequency hyperthermia causes tumor vasodilation, the photosensitizer infusion is accelerated to enhance drug accumulation in the tumor tissue.

[0042] In one specific embodiment, the control circuit further includes a first start-stop control unit and a second start-stop control unit. The first start-stop control unit is electrically connected at both ends to the main control system and the LED light source control module, respectively, while the second start-stop control unit is electrically connected at both ends to the main control system and the photosensitizer infusion pump control module, respectively. The main control system can precisely control the start and stop times of the LED light source and the photosensitizer infusion pump through these two start-stop control units according to a preset treatment plan. For example, the photosensitizer infusion pump can be started first via the second start-stop control unit, and after the photosensitizer reaches the tumor tissue and reaches a suitable concentration, the LED light source can be started via the first start-stop control unit, thereby ensuring that the photodynamic therapy achieves the best effect.

[0043] During treatment, if the LED light source or photosensitizer infusion pump unexpectedly starts or stops, it may affect the treatment effect and even harm the patient. The first and second start-stop control units add an extra layer of control protection to the system. The LED light source control module and photosensitizer infusion pump control module will only start or stop when the main control system issues the correct command, reducing the risk caused by misoperation. When abnormal situations occur during treatment, such as patient discomfort or equipment malfunction, the main control system can quickly stop the operation of the LED light source and photosensitizer infusion pump through the first and second start-stop control units, ensuring the patient's safety in a timely manner.

[0044] In this embodiment, the circuit structures of the first start-stop control unit and the second start-stop control unit are the same, both including a first resistor R1, a second resistor R2, a third resistor R3, a Zener diode D, and a third switch Q3. Taking the first start-stop control unit as an example, the two ends of the first resistor R1 are connected to the main control system and the gate of the third switch Q3, respectively. The drain of the third switch Q3 is connected to the power supply, and the source of the third switch Q3 is connected to the LED light source control module. One end of the second resistor R2 is connected to the gate of the third switch Q3. One end of the third resistor R3 and the cathode of the Zener diode D are connected to the source of the third switch Q3, respectively. The other ends of the second resistor R2, the other end of the third resistor R3, and the anode of the Zener diode D are connected together and grounded.

[0045] To address this, the main control system precisely controls the on / off state of the third switch Q3 via logic levels (high / low), thereby controlling the start and stop of the LED light source or photosensitizer infusion pump. This is strictly synchronized with the treatment process (e.g., "inject photosensitizer first, wait for enrichment, then turn on light therapy"), avoiding delays or errors caused by human operation. A Zener diode D prevents overvoltage at the load end, preventing the LED light source from burning out due to abnormal voltage or the infusion pump motor from running out of control due to high voltage (e.g., accidental activation causing motor overspeed). The first and second start / stop control units have identical structures, allowing for reuse of design parameters (e.g., resistor values, Zener diode models), simplifying hardware development and reducing costs. In the event of a single module failure (e.g., a damaged switch), a component of the same specification can be quickly replaced without redesigning the entire control circuit, improving maintenance efficiency.

[0046] Please refer to Figure 2 This application also provides a radiofrequency-photodynamic tumor killing therapy system. The therapy system uses a radiofrequency-photodynamic tumor killing therapy control circuit, including a radiofrequency generator, a radiofrequency output negative plate, a radiofrequency output electrode, an LED light source control unit, a photosensitizer injection pump control unit, a main control system, and a display module.

[0047] Specifically, the main control system is communicatively connected to the radio frequency (RF) generator, the LED light source control unit, the photosensitizer injection pump control unit, and the display module. The RF generator controls the RF output negative plate and the RF output electrode to form an RF output circuit. The RF output electrode integrates the LED light source and the photosensitizer injection channel, and the RF energy generated by the RF output electrode directly acts on the tumor tissue. The LED light source control unit controls the light source intensity of the LED, and the photosensitizer injection pump control unit controls the injection flow rate of the photosensitizer in the photosensitizer injection channel.

[0048] The main control system controls the output power of the radiofrequency generator and adjusts the output power in real time using a computational software algorithm. It receives the photosensitizer injection start signal and flow rate signal set by the computer and transmits them to the photosensitizer injection pump control unit; it also receives the LED light source start signal and intensity signal set by the computer and transmits them to the LED light source control unit. The radiofrequency generator produces a maximum radiofrequency power of 100W with an output power accuracy of ±1W. It forms a radiofrequency output circuit through the radiofrequency output electrode and the radiofrequency output negative electrode, generating ion-level oscillations near the radiofrequency output electrode to generate radiofrequency energy that heats and ablates tumor tissue. The display module shows the set radiofrequency output power. Users can modify parameters such as the set radiofrequency output power, LED light source intensity, and photosensitizer injection flow rate via a touchscreen, and the corresponding "time-radiofrequency output power-photosensitizer flow rate-LED light source intensity" graph is displayed, facilitating medical staff to view historical data and conduct treatment evaluations.

[0049] This treatment system uses radiofrequency energy to heat tumor cells in real time for ablation treatment. It also integrates an LED light source and releases photosensitizers simultaneously to achieve a synergistic effect between radiofrequency ablation and photodynamic therapy. This results in a clinical effect of "1+1≥2" between radiofrequency ablation and photodynamic therapy. It features significant efficacy, minimal trauma, high safety, and flexible operation, further improving the effectiveness and precision of tumor treatment.

[0050] Please refer to Figure 3 and Figure 4 In one specific embodiment, the radio frequency output electrode has a radio frequency needle for puncturing tumor tissue. An LED light source 2 is provided at the tip 1 of the radio frequency needle, and the LED light source 2 is connected to an LED light source cable 5 that passes through the radio frequency needle. A photosensitizer injection channel 7 is formed within the needle tube 3 of the radio frequency needle along its length, and a photosensitizer injection hole 6 is formed in the tube wall of the radio frequency needle. Furthermore, an insulating sleeve 4 is also fitted over the outside of the radio frequency needle.

[0051] The radiofrequency needle integrates three functions: radiofrequency energy output, LED light illumination, and photosensitizer injection. It allows for tumor localization and multimodal treatment with a single puncture, avoiding the cumbersome procedures of traditional multi-instrument, step-by-step operations (such as first inserting the radiofrequency needle, then implanting the optical fiber and injection catheter), thus reducing patient trauma and physician operation time. The optical path channel, photosensitizer injection channel 7, and radiofrequency energy output end are highly integrated at the needle tip 1, ensuring that the three treatment methods act on the same target area, avoiding treatment deviations caused by instrument displacement (such as misalignment between photodynamic light illumination and the radiofrequency thermal zone). The structural design of this radiofrequency output electrode, through multi-channel integration and advanced functional optimization, significantly improves the precision, minimal invasiveness, and synergistic effect of tumor treatment.

[0052] Furthermore, the RF output negative electrode plate is made of conductive material and has an adhesive layer on its exterior. The RF output negative electrode plate is typically attached to a smooth skin surface (such as the back or thigh) to participate in forming a complete RF output circuit.

[0053] The high-frequency current generated by the radiofrequency generator enters the tumor tissue through the radiofrequency output electrode (positive electrode), and then flows back to the device through the radiofrequency output negative electrode (negative electrode), forming a complete circuit. If the radiofrequency output negative electrode is missing or has poor contact, the current cannot form a closed loop, the radiofrequency energy cannot be effectively transferred, and the treatment effect is seriously affected.

[0054] The above description is merely a specific embodiment of this application, but the scope of protection of this application is not limited thereto. Any person skilled in the art can easily conceive of various equivalent modifications or substitutions within the technical scope disclosed in this application, and these modifications or substitutions should all be covered within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.

Claims

1. A radiofrequency-photodynamic tumor killing therapy control circuit, characterized in that: It includes a power supply module, an RF generator module, an RF output electrode, an LED light source control module, a photosensitizer injection pump control module, a main control system, and a display module; The main control system is electrically connected to the radio frequency generation module, the LED light source control module, the photosensitizer injection pump control module, and the display module, respectively. The power module is electrically connected to the radio frequency generation module, the LED light source control module, and the photosensitizer injection pump control module, respectively. The radio frequency generation module, LED light source control module, and photosensitizer injection pump control module are electrically connected to the radio frequency output electrode, respectively.

2. The radiofrequency-photodynamic tumor killing therapy control circuit according to claim 1, characterized in that, The radio frequency generation module includes a first switch, a second switch, and a transformer. The gates of the first switch and the second switch are electrically connected to the main control system, respectively. The drains of the first switch and the second switch are electrically connected to the input terminal of the transformer, respectively. The sources of the first switch and the second switch are grounded, respectively. The output terminal of the transformer is electrically connected to the radio frequency output electrode, and the power supply module is electrically connected to the taps of the transformer.

3. The radiofrequency-photodynamic tumor killing therapy control circuit according to claim 2, characterized in that, The radio frequency generation module also includes a first capacitor, the two ends of which are electrically connected to the transformer and the radio frequency output electrode, respectively.

4. The radiofrequency-photodynamic tumor killing therapy control circuit according to claim 2, characterized in that, The control circuit also includes a first inductor, the two ends of which are electrically connected to the power module and the taps of the transformer, respectively.

5. The radiofrequency-photodynamic tumor killing therapy control circuit according to claim 1, characterized in that, The LED light source control module includes an LED light source control unit and an LED light source. The two ends of the LED light source control unit are electrically connected to the main control system and one end of the LED light source, respectively. The LED light source control unit is also electrically connected to the power supply module, and the other end of the LED light source is electrically connected to the radio frequency output electrode.

6. The radiofrequency-photodynamic tumor killing therapy control circuit according to claim 1, characterized in that, The photosensitizer injection pump control module includes a photosensitizer injection pump control unit and a photosensitizer injection pump. The two ends of the photosensitizer injection pump control unit are electrically connected to the main control system and one end of the photosensitizer injection pump, respectively. The photosensitizer injection pump control unit is electrically connected to the power supply module, and the other end of the photosensitizer injection pump is electrically connected to the radio frequency output electrode.

7. The radiofrequency-photodynamic tumor killing therapy control circuit according to claim 1, characterized in that, The control circuit also includes a first start-stop control unit and a second start-stop control unit. The two ends of the first start-stop control unit are electrically connected to the main control system and the LED light source control module, respectively. The two ends of the second start-stop control unit are electrically connected to the main control system and the photosensitizer injection pump control module, respectively.

8. A radiofrequency-photodynamic tumor killing therapy system, using the control circuit described in any one of claims 1-7, characterized in that, It includes a radio frequency generator, a radio frequency output negative plate, a radio frequency output electrode, an LED light source control unit, a photosensitizer injection pump control unit, a main control system, and a display module; The main control system is communicatively connected to the radio frequency generator, the LED light source control unit, the photosensitizer injection pump control unit, and the display module, respectively. The radio frequency generating device controls the radio frequency output negative plate and the radio frequency output electrode to form a radio frequency output circuit. The radio frequency output electrode integrates an LED light source and a photosensitizer injection channel. The radio frequency energy generated by the radio frequency output electrode directly acts on the tumor tissue. The LED light source control unit controls the light source intensity of the LED light source, and the photosensitizer injection pump control unit controls the injection flow rate of the photosensitizer in the photosensitizer injection channel.

9. The radiofrequency-photodynamic tumor killing therapy system according to claim 8, characterized in that, The radio frequency output electrode has a radio frequency needle for puncturing into tumor tissue. The tip of the radio frequency needle is provided with the LED light source. The photosensitizer injection channel is formed inside the tube of the radio frequency needle, and the tube wall of the radio frequency needle has a photosensitizer injection hole.

10. The radiofrequency-photodynamic tumor killing therapy system according to claim 8, characterized in that, The radio frequency output negative electrode plate is made of conductive material, and the radio frequency output negative electrode plate has an adhesive layer on the outside.

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