A stem cell exosome preservation device
Patent Information
- Application Number
- CN202522407878.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-13
- Publication Date
- 2026-10-20
- Estimated Expiration
- 2035-11-13
AI Technical Summary
1、现有的干细胞外泌体保存装置,需要通过人工进行置放,容易使细胞盒的周围残留细菌,影响干细胞的储存;
1、本实用新型提供一种干细胞外泌体保存装置,滑动装置主要是依靠滑轨对滑动装置进行移动支撑,卡板卡接于限位盒的正面保持滑轨安装的稳定性,电机通过固定盒支撑装置的一侧,连接块卡接于滑轨的一侧,螺纹杆插接于滑块的内部,然后通过启动电机,使螺纹杆推动连接块,促使安装盒带动液压升降杆进行移动,液压升降杆的底部连接安装板,安装板的顶部套接夹环,通过夹环卡接细胞盒,夹环内部有金属条,方便能够支撑变形,使得装置对细胞盒夹持更加稳定,更方便对细胞进行传递,减少人工触碰,使得细胞存储更加长久。
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Figure CN224863795U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of exosome preservation technology, specifically to a stem cell exosome preservation device. Background Technology
[0002] Exosomes derived from mesenchymal stem cells can be transferred between cells through their contents, such as proteins, and can exert similar functions as mesenchymal stem cells, such as tissue repair, immunosuppression, and immunomodulation. Therefore, exosome research is expected to become a key research direction in the future biomedical field.
[0003] Existing mesenchymal stem cell exosome preservation devices often require manual handling when placing or removing storage tubes. This manual handling may lead to bacterial growth in the storage box, which could damage the stem cell structure. Furthermore, manual handling usually only allows for the removal of individual storage tubes, which is inefficient and exposes all storage tubes to room temperature, thus reducing the preservation effect of mesenchymal stem cells.
[0004] The existing technology has the following problems: 1. Existing stem cell exosome preservation devices require manual placement, which can easily lead to bacteria remaining around the cell box, affecting the storage of stem cells. 2. Existing stem cell exosome preservation devices do not maintain the storage temperature of the cell boxes sufficiently, and the cell boxes are not placed stably and are prone to tilting. Utility Model Content
[0005] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is as follows: A stem cell exosome preservation device includes a box body with a groove on one side and a loading box at the other end. A support rod is fixedly connected to the inner wall of the groove, and a sliding device is fixedly connected to the top of the support rod. A clamping device is movably connected to one side of the sliding device. An insertion groove is formed in the middle of the inner wall of the box body. A placement seat is fixedly connected to the inside of the loading box. An observation window is fixedly connected to the front of the loading box. A baffle is movably inserted into the insertion groove. A connecting plate is fixedly connected to the upper front end of the baffle. A hydraulic telescopic rod is fixedly connected to the rear end of the connecting plate. The rear end of the hydraulic telescopic rod is fixedly installed on the front of the box body.
[0006] A further improvement of the present invention is that the sliding device includes a limiting box, the back of which is fixedly connected to the front of the support rod, a slide rail is snapped onto the front of the limiting box, a locking plate is movably snapped onto the front of the limiting box, a fixing box is fixedly connected to one end of the slide rail, a motor is fixedly connected to the inner wall of the fixing box, and a threaded rod is fixedly connected to the output end of the motor.
[0007] A further improvement of this utility model is that: a slot is provided on the top of the slide rail, the card plate is engaged with the front of the limiting box and wraps around one end of the slide rail, and the threaded rod is inserted into one end of the slot.
[0008] A further improvement of the present invention is that the clamping device includes a connecting block, a slider is fixedly connected to the inner wall of the connecting block, an installation box is fixedly connected to the front of the slider, a hydraulic lifting rod is fixedly connected inside the installation box, an installation plate is fixedly connected to the bottom of the hydraulic lifting rod, a clamping ring is movably connected to one side of the installation plate, and a insertion hole is opened at the bottom of one end of the clamping ring.
[0009] A further improvement of this utility model is that: one side of the connecting block is movably inserted into the front of the slide rail, the slider is inserted into the inside of the slot, and the insertion hole is inserted into the inside of the insertion hole.
[0010] A further improvement of the present invention is that: the placement seat includes a base, a plug box is fixedly connected to the top of the base, a driving end is fixedly connected to one side of the base, an insertion end is fixedly connected to one end of the driving end, an insertion hole is opened on the top of the plug box, an installation groove is opened on the inner wall of the insertion hole, a spring rod is fixedly connected inside the installation groove, and a clamping plate is fixedly connected to one end of the spring rod.
[0011] A further improvement of this utility model is that: the top of the base is provided with a discharge groove, and the base is fixedly installed inside the loading box.
[0012] Due to the adoption of the above technical solution, the technological progress achieved by this utility model compared to the prior art is as follows: 1. This utility model provides a stem cell exosome preservation device. The sliding device mainly relies on a slide rail for movement and support. A clamping plate is engaged with the front of the limiting box to maintain the stability of the slide rail installation. The motor supports one side of the fixed box, and the connecting block is engaged with one side of the slide rail. The threaded rod is inserted into the inside of the slider. Then, by starting the motor, the threaded rod pushes the connecting block, causing the mounting box to move the hydraulic lifting rod. The bottom of the hydraulic lifting rod is connected to the mounting plate, and the top of the mounting plate is fitted with a clamping ring. The cell box is engaged through the clamping ring. The clamping ring has a metal strip inside to facilitate deformation support, making the device hold the cell box more stably, facilitating cell transfer, reducing manual touch, and enabling longer cell storage.
[0013] 2. This utility model provides a stem cell exosome preservation device. The base supports the insertion box, the cell box is inserted into the insertion hole, the spring rod connects to the clamping plate, the cell box is snapped into the inner wall of the clamping plate, and the device clamps the cell box by the extension and retraction of the spring rod. The device replenishes the cooling liquid from one end of the insertion end, and then the cold air is discharged from the top of the discharge tank to cool the area around the top insertion box, which facilitates cell storage. Attached Figure Description
[0014] Figure 1 This is a schematic diagram of the stem cell exosome preservation device of this utility model; Figure 2 This is a schematic diagram of the sliding device of this utility model; Figure 3 This is a schematic diagram of the clamping device of this utility model; Figure 4 This is a schematic diagram of the structure of the placement base of this utility model.
[0015] In the diagram: 1. Box body; 2. Groove; 3. Loading box; 4. Support rod; 5. Sliding device; 6. Clamping device; 7. Insertion slot; 8. Placement seat; 9. Observation window; 10. Hydraulic telescopic rod; 11. Connecting plate; 12. Baffle; 51. Limit box; 52. Clamping plate; 53. Slide rail; 54. Fixing box; 55. Motor; 56. Threaded rod; 57. Slot; 61. Connecting block; 62. Slider; 63. Mounting box; 64. Hydraulic lifting rod; 65. Mounting plate; 66. Clamping ring; 67. Insertion hole; 81. Base; 82. Insertion box; 83. Drive end; 84. Insertion end; 85. Insertion hole; 86. Mounting slot; 87. Spring rod; 88. Clamping plate; 89. Discharge slot. Detailed Implementation
[0016] The present invention will be further described in detail below with reference to embodiments: Example
[0017] like Figure 1-4 As shown, this utility model provides a stem cell exosome preservation device, including a box 1. A groove 2 is provided on one side of the box 1, and a loading box 3 is provided at the other end of the box 1. A support rod 4 is fixedly connected to the inner wall of the groove 2. A sliding device 5 is fixedly connected to the top of the support rod 4. A clamping device 6 is movably connected to one side of the sliding device 5. An insertion groove 7 is provided in the middle part of the inner wall of the box 1. A placement seat 8 is fixedly connected to the inside of the loading box 3. An observation window 9 is fixedly connected to the front of the loading box 3. A baffle 12 is movably inserted into the inside of the insertion groove 7. A connecting plate 11 is fixedly connected to the upper end of the front of the baffle 12. A hydraulic telescopic rod 10 is fixedly connected to the rear end of the connecting plate 11. The rear end of the hydraulic telescopic rod 10 is fixedly installed on the front of the box 1.
[0018] In this embodiment, the support rod 4 installed inside the box 1 supports the sliding device 5. The sliding device 5 pushes the clamping device 6 to one side and into the loading box 3. The clamping device 6 clamps the cell box and transports it laterally into the loading box 3. Then, the cell box is transported downward and placed inside the placement seat 8. Mechanical transportation can reduce the bacteria carried by humans. The placement of cells inside can be observed through the observation window 9 on one side, which is more suitable for cell storage. Example
[0019] like Figure 1-4 As shown, based on Embodiment 1, this utility model provides a technical solution: Preferably, the sliding device 5 includes a limiting box 51, the back of the limiting box 51 is fixedly connected to the front of the support rod 4, the front of the limiting box 51 is engaged with a slide rail 53, the front of the limiting box 51 is movably engaged with a locking plate 52, one end of the slide rail 53 is fixedly connected to a fixing box 54, the inner wall of the fixing box 54 is fixedly connected to a motor 55, and the output end of the motor 55 is fixedly connected to a threaded rod 56.
[0020] The top of the slide rail 53 has a slot 57, and the card plate 52 is engaged with the front of the limiting box 51 and wraps around one end of the slide rail 53. The threaded rod 56 is inserted into one end of the slot 57.
[0021] The clamping device 6 includes a connecting block 61, a slider 62 is fixedly connected to the inner wall of the connecting block 61, an mounting box 63 is fixedly connected to the front of the slider 62, a hydraulic lifting rod 64 is fixedly connected inside the mounting box 63, an mounting plate 65 is fixedly connected to the bottom of the hydraulic lifting rod 64, a clamping ring 66 is movably connected to one side of the mounting plate 65, and a insertion hole 67 is opened at the bottom of one end of the clamping ring 66.
[0022] One side of the connecting block 61 is movably inserted into the front of the slide rail 53, the slider 62 is inserted into the inside of the slot 57, and the insertion hole 67 is inserted into the inside of the insertion hole 67.
[0023] In this embodiment, the sliding device 5 mainly relies on the slide rail 53 for movement support. The clamping plate 52 is clamped to the front of the limiting box 51 to maintain the stability of the slide rail 53 installation. The motor 55 supports one side of the device through the fixing box 54. The connecting block 61 is clamped to one side of the slide rail 53. The threaded rod 56 is inserted into the inside of the slider 62. Then, by starting the motor 55, the threaded rod 56 pushes the connecting block 61, causing the mounting box 63 to drive the hydraulic lifting rod 64 to move. The bottom of the hydraulic lifting rod 64 is connected to the mounting plate 65, and the top of the mounting plate 65 is fitted with a clamping ring 66. The cell box is clamped through the clamping ring 66. The clamping ring 66 has a metal strip inside to facilitate support for deformation, making the device clamp the cell box more stably, making it easier to transfer cells, reducing manual touch, and making cell storage longer. Example
[0024] like Figure 1-4 As shown, based on Embodiment 1, this utility model provides a technical solution: Preferably, the placement seat 8 includes a base 81, a plug box 82 is fixedly connected to the top of the base 81, a driving end 83 is fixedly connected to one side of the base 81, an insertion end 84 is fixedly connected to one end of the driving end 83, an insertion hole 85 is opened on the top of the plug box 82, an installation groove 86 is opened on the inner wall of the insertion hole 85, a spring rod 87 is fixedly connected inside the installation groove 86, and a clamping plate 88 is fixedly connected to one end of the spring rod 87.
[0025] The top of the base 81 is provided with a discharge slot 89, and the base 81 is fixedly installed inside the loading box 3.
[0026] In this embodiment, the base 81 supports the insertion box 82, the cell box is inserted into the insertion hole 85, the spring rod 87 is connected to the clamping plate 88, the cell box is snapped into the inner wall of the clamping plate 88, and the spring rod 87 is used for telescopic clamping, so that the device clamps the cell box, the refrigerant is replenished from one end of the insertion end 84, and then the cold air is discharged from the top of the discharge groove 89 to cool the area around the top insertion box 82, which facilitates cell storage.
[0027] The working principle of this stem cell exosome preservation device will be explained in detail below.
[0028] like Figure 1-4As shown, when this stem cell exosome preservation device is in use, the support rod 4 installed inside the housing 1 supports the sliding device 5. The sliding device 5 pushes the clamping device 6 to one side, pushing it into the loading box 3. The clamping device 6 clamps the cell box and transports it laterally into the loading box 3. Then, the cell box is transported downwards and placed inside the placement seat 8. Mechanical transport can reduce the bacteria carried by humans. The placement of cells inside can be observed through the observation window 9 on one side, which is more suitable for cell storage. The sliding device 5 is mainly supported by the slide rail 53. The clamping plate 52 is engaged with the front of the limiting box 51 to maintain the stability of the slide rail 53 installation. The motor 55 is supported by one side of the fixing box 54. The connecting block 61 is engaged with one side of the slide rail 53. The threaded rod 56 is inserted into the inside of the slider 62. Then, by starting the motor 55, the sliding device is moved. The threaded rod 56 pushes the connecting block 61, causing the mounting box 63 to move the hydraulic lifting rod 64. The bottom of the hydraulic lifting rod 64 is connected to the mounting plate 65, and the top of the mounting plate 65 is fitted with a clamping ring 66. The cell box is secured by the clamping ring 66, which has a metal strip inside to support deformation, making the device hold the cell box more stably, facilitating cell transfer, reducing manual touch, and extending cell storage time. The base 81 supports the insertion box 82, and the cell box is inserted into the insertion hole 85. The spring rod 87 connects to the clamping plate 88, and the cell box is secured to the inner wall of the clamping plate 88. The spring rod 87 extends and retracts to hold the cell box, allowing the device to clamp it. Refrigerant is replenished from one end of the insertion end 84, and then cold air is discharged from the top of the discharge tank 89 to cool the area around the top insertion box 82, facilitating cell storage.
[0029] The present invention has been described in detail above. However, modifications or improvements can be made to it, which will be obvious to those skilled in the art. Therefore, any modifications or improvements that do not depart from the spirit of the present invention are within the protection scope of the present invention.
Claims
1. A stem cell exosome preservation device, comprising a housing (1), characterized in that: A groove (2) is provided on one side of the box (1), and a loading box (3) is provided at the other end of the box (1). A support rod (4) is fixedly connected to the inner wall of the groove (2). A sliding device (5) is fixedly connected to the top of the support rod (4). A clamping device (6) is movably connected to one side of the sliding device (5). A insertion groove (7) is provided in the middle part of the inner wall of the box (1). A placement seat (8) is fixedly connected inside the loading box (3). An observation window (9) is fixedly connected to the front of the loading box (3). A baffle (12) is movably inserted into the insertion groove (7). A connecting plate (11) is fixedly connected to the upper front end of the baffle (12). A hydraulic telescopic rod (10) is fixedly connected to the rear end of the connecting plate (11). The rear end of the hydraulic telescopic rod (10) is fixedly installed on the front of the box (1).
2. The stem cell exosome preservation device according to claim 1, characterized in that: The sliding device (5) includes a limiting box (51), the back of which is fixedly connected to the front of the support rod (4), a slide rail (53) is snapped onto the front of the limiting box (51), a locking plate (52) is movably snapped onto the front of the limiting box (51), a fixing box (54) is fixedly connected to one end of the slide rail (53), a motor (55) is fixedly connected to the inner wall of the fixing box (54), and a threaded rod (56) is fixedly connected to the output end of the motor (55).
3. The stem cell exosome preservation device according to claim 2, characterized in that: The top of the slide rail (53) is provided with a slot (57), the card plate (52) is engaged with the front of the limiting box (51) and wraps around one end of the slide rail (53), and the threaded rod (56) is inserted into one end of the slot (57).
4. The stem cell exosome preservation device according to claim 1, characterized in that: The clamping device (6) includes a connecting block (61), a slider (62) is fixedly connected to the inner wall of the connecting block (61), a mounting box (63) is fixedly connected to the front of the slider (62), a hydraulic lifting rod (64) is fixedly connected inside the mounting box (63), a mounting plate (65) is fixedly connected to the bottom of the hydraulic lifting rod (64), a clamping ring (66) is movably connected to one side of the mounting plate (65), and a plug-in hole (67) is opened at the bottom of one end of the clamping ring (66).
5. The stem cell exosome preservation device according to claim 4, characterized in that: One side of the connecting block (61) is movably inserted into the front of the slide rail (53), the slider (62) is inserted into the inside of the slot (57), and the insertion hole (67) is inserted into the inside of the insertion hole (67).
6. The stem cell exosome preservation device according to claim 1, characterized in that: The placement seat (8) includes a base (81), a plug box (82) is fixedly connected to the top of the base (81), a drive end (83) is fixedly connected to one side of the base (81), an insertion end (84) is fixedly connected to one end of the drive end (83), an insertion hole (85) is opened on the top of the plug box (82), an installation groove (86) is opened on the inner wall of the insertion hole (85), a spring rod (87) is fixedly connected inside the installation groove (86), and a clamping plate (88) is fixedly connected to one end of the spring rod (87).
7. The stem cell exosome preservation device according to claim 6, characterized in that: The base (81) has a discharge slot (89) on its top and is fixedly installed inside the loading box (3).