An aid for myelin microinjection

Abstract

The utility model discloses a kind of auxiliary parts for medullary sheath microinjector, including hose, needle and buckle, wherein, hose has first end and second end, first end is used to connect injector, hose is transparent material and has scale, needle is fixedly connected in second end by connecting piece, buckle is set at the position of hose close to first end position.The utility model provides a kind of auxiliary parts for medullary sheath microinjector, needle is connected with injector by hose, due to interval hose, the operation of connecting injector will not affect the position of needle, improve the accuracy of administration;At the same time, hose is transparent material, it is convenient to observe whether cerebrospinal fluid backflow is smooth, volume is set to 200 μL or so, it will not cause life threat to it, and whether backflow is smooth can be observed, injection material is not likely to cause excessive waste, when backflow cerebrospinal fluid fills hose, lock hose using buckle, prevent backflow cerebrospinal fluid excessive life threat to animal.

Description

Technical Field

[0001] This utility model relates to the technical field of myelin injection drug delivery devices for non-rodent animals, and in particular to an auxiliary component for a myelin micro-syringe. Background Technology

[0002] Microinjection of myelin is currently one of the methods used in pharmacological, pharmacokinetic, and toxicological experiments. When administering microinjection of myelin to non-rodent animals, the injection site is typically at the L4-L5 lumbar intervertebral space. The procedure requires that cerebrospinal fluid (CSF) return be present and unobstructed after needle insertion before connecting the syringe. During syringe connection, the needle insertion position must be strictly maintained to ensure accurate drug administration, which presents certain operational difficulties and risks. Furthermore, the amount of CSF returning must be precise; too much can threaten the animal's life, while too little will prevent successful injection of the test substance into the myelin sheath. However, in current technologies, the rigid connection between the syringe and needle used for microinjection of myelin often leads to needle displacement, resulting in inaccurate drug administration, and the amount of CSF returning cannot be effectively controlled and measured. Utility Model Content

[0003] The technical problem to be solved by this utility model is to provide an auxiliary component for a myelin micro-syringe, which can keep the needle position stationary when the syringe is connected, and can effectively observe and measure the refluxed cerebrospinal fluid.

[0004] To solve the above-mentioned technical problems, the present invention provides an auxiliary component for a myelin microsyringe, comprising:

[0005] A flexible tube having a first end and a second end, the first end being used to connect to a syringe, the flexible tube being made of transparent material and having a volume of 190-210 μL;

[0006] The needle is fixedly connected to the second end via a connector;

[0007] A clip is provided at the position of the hose near the first end.

[0008] Preferably, the volume of the hose is 200 μL.

[0009] Preferably, the hose is made of PVC, PE, PC or PP.

[0010] Preferably, the connector is provided with wings for gripping.

[0011] Preferably, the wing has protrusions to increase grip friction.

[0012] Preferably, the needle used is a 0.55mm needle.

[0013] Preferably, the first end is formed as a connector, and the outer surface of the connector has protrusions to increase friction.

[0014] This invention provides an auxiliary component for a myelin micro-syringe. The needle is connected to the syringe via a tubing. Due to the tubing, the operation of connecting the syringe does not affect the position of the needle, improving the accuracy of drug administration. Simultaneously, the tubing is made of transparent material, facilitating observation of the smooth flow of cerebrospinal fluid. With a volume of approximately 200 μL, it poses no threat to the animal's life and allows for observation of the smoothness of the return flow, preventing excessive waste of injected material. When the tubing is full of cerebrospinal fluid, a clip locks it in place to prevent excessive cerebrospinal fluid return from threatening the animal's life. Attached Figure Description

[0015] To more clearly illustrate the technical solution of this utility model, the drawings used in this utility model will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of an embodiment of the auxiliary component for the myelin microsyringe of this utility model;

[0017] In the diagram, 1-hose; 11-gradation; 12-first end; 13-second end; 14-connector; 15-protrusion; 2-needle; 21-connector; 22-wing; 23-protrusion; 3-buckle. Detailed Implementation

[0018] The technical solutions of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0019] refer to Figure 1 This invention illustrates an auxiliary component for a myelin microsyringe, comprising:

[0020] A flexible tube having a first end and a second end, the first end being used to connect to a syringe, the flexible tube being made of transparent material and having a volume of 190-210 μL;

[0021] The needle is fixedly connected to the second end via a connector;

[0022] A clip is provided at the position of the hose near the first end.

[0023] In this embodiment of the invention, the needle is connected to the syringe via a flexible tube, with the needle and syringe located at opposite ends of the tube. When the needle is inserted into the L4-L5 lumbar intervertebral space of a non-rodent animal, connecting the syringe afterward, due to the flexible tube, does not affect the needle's position, thus improving the accuracy of drug administration. Simultaneously, the transparent material of the flexible tube facilitates observation of the smooth flow of cerebrospinal fluid (CSF). Furthermore, for most non-rodent animals, approximately 200 μL of CSF refluxing will not pose a life-threatening risk, and the smoothness of the refluxing can be observed. Preparing an additional 200 μL of injection material will not result in excessive waste. Therefore, the volume of the flexible tube in this invention is set to 190-210 μL. After the refluxing CSF fills the tube, it can be connected to the syringe to prevent gas contamination. When the refluxing CSF fills the tube, a clip is used to lock the tube, preventing excessive CSF refluxing from threatening the animal's life. It should be noted that in this utility model, the needle is connected to the second end of the tubing via a connector. In the prior art, needles and connectors that conform to medical standards are applicable to this utility model, such as metal needles with plastic connectors, etc., which will not be elaborated here.

[0024] In one specific embodiment, the volume of the tubing is 200 μL.

[0025] In one specific embodiment, the tubing is made of PVC, PE, PC, or PP. Understandably, the tubing is made of medical-grade PVC, PE, PC, or PP.

[0026] In one specific embodiment, the connector is provided with wings for gripping. Preferably, the wings have protrusions to increase grip friction. Understandably, providing wings increases the stability of holding the needle, thereby increasing the stability of needle insertion during surgery and ensuring positional accuracy; the protrusions on the surface of the wings increase friction, especially during insertion, the greater friction prevents relative sliding between the hand and the wings, which could lead to deviation in the insertion position.

[0027] In one specific embodiment, the needle used is a 0.55mm needle. Understandably, this needle size meets the surgical needs of micro-injection of myelin sheath in most non-rodent animals.

[0028] In one specific embodiment, the first end is formed as a connector, the outer surface of which has protrusions to increase friction. In this specific embodiment, the shape of the connector is not limited, but its opening must match the shape of the syringe's outlet. The connection between the connector and the syringe is achieved, for example, through existing technologies such as interference fit, which will not be elaborated here.

[0029] The above description is only a preferred embodiment of the present utility model and is not intended to limit the scope of protection of the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the scope of protection of the present utility model.

Claims

1. An auxiliary component for a myelin microsyringe, characterized in that, include: A flexible tube having a first end and a second end, the first end being used to connect to a syringe, the flexible tube being made of transparent material and having a volume of 190-210 μL; The needle is fixedly connected to the second end by a connector, and the needle is a 0.55mm needle. A clip is provided at the position of the hose near the first end.

2. The auxiliary component for a myelin microsyringe as described in claim 1, characterized in that, The volume of the hose is 200 μL.

3. The auxiliary component for a myelin microsyringe as described in claim 1, characterized in that, The hose is made of PVC, PE, PC or PP.

4. The auxiliary component for a myelin microsyringe as described in claim 1, characterized in that, The connector is provided with wings for gripping.

5. The auxiliary component for a myelin microsyringe as described in claim 4, characterized in that, The wing has protrusions to increase grip friction.

6. The auxiliary component for a myelin microsyringe as described in claim 1, characterized in that, The first end is formed as a connector, and the outer surface of the connector has protrusions to increase friction.

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