A controlled release patch for wound healing

Abstract

The utility model discloses a kind of controlled-release patches for wound healing, including shell, the bottom of shell is fixedly equipped with adhesive layer, the bottom of shell is equipped with assembly slot, first electrode patch is fixedly equipped in assembly slot, the top of shell is equipped with liquid storage cavity, the bottom of liquid storage cavity is equipped with assembly hole, first hydrogel layer is connected in assembly hole, the top of shell is equipped with first lid, connecting assembly is equipped between shell and first lid, the bottom of first lid is fixedly equipped with electric connection male head, electric connection female head is embedded and installed in shell, the position of electric connection male head and electric connection female head corresponds. The utility model has two kinds of usage, can satisfy different use needs in the process of wound healing treatment, first lid and second lid are detachably fixedly connected with shell by connecting assembly, so that the replacement process of first lid and second lid and internal hydrogel layer is simple, convenient, easy to operate.

Description

Technical Field

[0001] This utility model relates to the field of wound healing technology, specifically to a controlled-release patch for wound healing. Background Technology

[0002] Wound healing is a complex and orderly biological process involving the activation of the coagulation system, inflammatory response, proliferation of granulation tissue, and reepithelialization of the skin defect.

[0003] A technical solution is disclosed in Chinese invention patent document CN119184963A, entitled "An Electro-Controlled Release Hydrogel Patch for Wound Healing": a reservoir is set up to replenish the drug solution used in the hydrogel patch for wound healing, and an electrode patch is also set up to electro-control the release of the drug through the electrode patch, thereby accelerating the release of the drug and the healing of the wound.

[0004] However, the aforementioned patches have limited practical applications, as they only utilize a single electro-controlled release hydrogel solution process. If bactericidal and bacteriostatic effects are required during wound healing, a single electro-controlled release patch cannot meet the comprehensive needs of wound healing treatment. Therefore, we propose a controlled-release patch for wound healing. Utility Model Content

[0005] The purpose of this invention is to provide a controlled-release patch for wound healing, so as to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a controlled-release patch for wound healing, comprising a shell, an adhesive layer fixedly mounted at the bottom of the shell, an assembly groove formed at the bottom of the shell, a first electrode patch fixedly mounted in the assembly groove, a liquid storage cavity formed at the top of the shell, an assembly hole formed at the bottom of the liquid storage cavity, a first hydrogel layer snapped into the assembly hole, a first cap mounted at the top of the shell, a connecting assembly between the shell and the first cap, a male connector fixedly mounted at the bottom of the first cap, and a female connector embedded in the shell, the positions of the male connector and the female connector corresponding to each other.

[0007] Preferably, a second electrode patch is fixedly mounted on the bottom of the first cover, and a first circuit board and a first button battery are embedded in the top of the first cover.

[0008] Preferably, the connecting assembly includes a connecting shaft, which is fixedly connected to the bottom of the first cover, and a connecting hole is provided on the top of the housing, with a magnet fixedly mounted at the bottom of the connecting hole.

[0009] Preferably, a waterproof sleeve is fitted between the first hydrogel layer and the assembly hole.

[0010] Preferably, the sidewalls of the housing are provided with opening slots symmetrically on the left and right.

[0011] Preferably, a second hydrogel layer is snapped into the assembly hole, and a second cap is detachably and fixedly connected to the top of the housing via a connecting assembly.

[0012] Preferably, an LED light is fixedly mounted on the bottom of the second cover, and a second circuit board and a second button battery are embedded in the top of the second cover.

[0013] Preferably, the bottom of the second cover is fixedly fitted with an auxiliary fixing ring.

[0014] Compared with the prior art, the beneficial effects of this utility model are: a controlled-release patch for wound healing has two usage methods. During the wound healing treatment, the corresponding usage method can be selected according to the specific needs. When it is necessary to accelerate the release of the drug solution and improve the treatment speed of wound healing, the first hydrogel layer and the first cap can be assembled together. During use, the release of the drug solution on the wound can be accelerated by the cooperation of the first electrode patch and the second electrode patch and the good conductivity of the first hydrogel layer, thereby accelerating the healing of the wound.

[0015] When bactericidal and bacteriostatic agents are needed during wound healing, the second hydrogel layer and the second cap are assembled and fixed with the shell. During the wound healing treatment of the second hydrogel layer, the LED light at the bottom of the second cap can illuminate the second hydrogel layer, so that the photocatalytic bactericidal layer inside can be continuously exposed to light and decompose to release bactericidal and bacteriostatic substances. Thus, the second hydrogel layer can maintain the bactericidal and bacteriostatic effect on the wound during the wound healing treatment.

[0016] This utility model has two usage modes, which can meet different usage needs in the wound healing treatment process. The first and second caps are detachably and fixedly connected to the shell through connecting components, so that the replacement of the first and second caps and the internal hydrogel layer is simple, convenient and easy to operate. Attached Figure Description

[0017] Figure 1 This is a perspective view of Embodiment 1 of the present utility model.

[0018] Figure 2 This is a structural schematic diagram of Embodiment 1 of the present utility model.

[0019] Figure 3 This is a schematic diagram of the internal connection hole of the housing of this utility model.

[0020] Figure 4 This is a schematic diagram of the structure of the first cap of this utility model.

[0021] Figure 5 This is a partial cross-sectional view of Embodiment 1 of the present invention.

[0022] Figure 6 This is a structural schematic diagram of Embodiment 2 of the present invention.

[0023] Figure 7 This is a schematic diagram of the structure of the second cap of this utility model.

[0024] Figure 8 This is a partial cross-sectional view of Embodiment 2 of the present invention.

[0025] In the diagram: 1. Shell; 2. Adhesive layer; 3. Assembly groove; 4. First electrode patch; 5. Liquid storage chamber; 6. Assembly hole; 7. First hydrogel layer; 8. First cap; 81. Second electrode patch; 82. First circuit board; 83. First button battery; 9. Second cap; 91. LED light; 92. Second circuit board; 93. Second button battery; 94. Auxiliary fixing ring; 10. Connecting assembly; 101. Connecting shaft; 102. Connecting hole; 103. Magnet block; 11. Opening groove; 12. Male connector; 13. Female connector; 14. Second hydrogel layer; 15. Waterproof sleeve. Detailed Implementation

[0026] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention.

[0027] Example 1

[0028] Please see Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 This utility model provides a technical solution: a controlled-release patch for wound healing, including a shell 1, an adhesive layer 2 fixedly connected to the bottom of the shell 1, the adhesive layer 2 being annular and made of medical pressure-sensitive adhesive, the shell 1 can be adhered and fixed near the patient's wound by setting the adhesive layer 2, an assembly groove 3 is provided at the bottom of the shell 1, a first electrode patch 4 is fixedly assembled in the assembly groove 3, a liquid storage cavity 5 is provided at the top of the shell 1, an assembly hole 6 is provided at the bottom center of the liquid storage cavity 5, the assembly hole 6 is used for assembling and fixing the first hydrogel layer 7, the liquid storage cavity 5 is used for storing the drug solution, and the drug solution stored in the liquid storage cavity 5 is used to supply the first hydrogel layer 7 with the drug solution.

[0029] The first hydrogel layer 7 is cylindrical in shape and is a conductive hydrogel layer, comprising graphene oxide and metformin. Graphene oxide and metformin are incorporated into the hydrogel crosslinking network, which is formed by the hydrogel materials chitosan and polyvinyl alcohol. Specifically, the conductive hydrogel is prepared as follows: graphene oxide and polyvinyl alcohol are dissolved in water and heated and stirred at 95°C for 5 hours to obtain a first precursor solution (the mass concentration of polyvinyl alcohol in the first precursor solution is 9%); metformin is then mixed with chitosan. Dissolved in water and stirred at room temperature to obtain a second precursor solution (the mass concentration of chitosan in the second precursor solution is 2%); the first precursor solution and the second precursor solution are mixed at a volume ratio of 1:1 and stirred (in the mixed solution, the mass ratio of graphene oxide to the sum of the masses of polyvinyl alcohol and chitosan is 0.036:1, and the mass ratio of metformin to the sum of the masses of polyvinyl alcohol and chitosan is 0.054:1), and subjected to three freeze-thaw cycles at -20℃ to form a conductive hydrogel layer.

[0030] A waterproof sleeve 15 is fitted between the first hydrogel layer 7 and the assembly hole 6. The waterproof sleeve 15 seals the connection between the first hydrogel layer 7 and the assembly hole 6, preventing the liquid stored in the liquid storage chamber 5 from leaking from the connection between the first hydrogel layer 7 and the assembly hole 6.

[0031] A first cover 8 is fitted to the top of the housing 1, and a connecting component 10 is fitted between the housing 1 and the first cover 8. The connecting component 10 enables detachable assembly and disassembly between the housing 1 and the first cover 8, making the disassembly and installation process simpler and more convenient. Figure 3 and Figure 4 As shown, the connecting assembly 10 includes a connecting shaft 101, which is uniformly and integrally formed on the bottom of the first cover 8. The top of the housing 1 is uniformly provided with connecting holes 102, the diameter of which is adapted to the diameter of the connecting shaft 101. The connecting shaft 101 is made of ferrous metal. A magnet 103 is fixedly mounted on the bottom of the connecting hole 102. After the connecting shaft 101 is inserted into the connecting hole 102, it can be attracted to the magnet 103 at the bottom, thereby fixing the first cover 8 to the housing 1.

[0032] like Figure 3 As shown, the left and right side walls of the housing 1 are integrally formed with opening grooves 11, which facilitate the separation of the first cover 8 from the housing 1.

[0033] like Figure 2 , Figure 4 and Figure 5As shown, a second motor patch 81 is fixedly mounted on the bottom of the first cover 8 via a mounting shaft. After the first cover 8 is assembled and fixed to the housing 1, the second motor patch 81 is tightly attached to the top of the first hydrogel layer 7. A first circuit board 82 and a first button battery 83 are embedded in the top of the first cover 8. The first button battery 83 is electrically connected to the first circuit board 82 to supply power to the first circuit board 82. The first circuit board 82 is equipped with a voltage regulation circuit, a potentiometer, and a controller. The voltage regulation circuit is a DC-DC voltage regulation circuit that adjusts the voltage difference between the first electrode patch 4 and the second electrode patch 81. The potentiometer acts as a current-limiting resistor. The controller controls the resistance value of the potentiometer by opening and closing the voltage regulation circuit according to the drug delivery requirements during use, thereby adjusting the voltage difference between the first electrode patch 4 and the second electrode patch 81 to achieve the purpose of controlling the drug delivery speed.

[0034] like Figure 4 and Figure 5 As shown, a male connector 12 is fixedly mounted on the bottom of the first cover 8, which is electrically connected to the first circuit board 82. A female connector 13 is embedded in the housing 1, and the positions of the female connector 13 and the male connector 12 are corresponding. The female connector 13 is electrically connected to the first electrode patch 4. After the first cover 8 and the housing 1 are assembled and fixed, the male connector 12 is inserted into the female connector 13, so that the first electrode patch 4 and the first circuit board 82 in the first cover 8 form a closed circuit. Power is supplied to it through the first circuit board 82, and its voltage is regulated during use.

[0035] Working principle: such as Figure 1 and Figure 2 As shown, when the electrically controlled release hydrogel is needed to heal the wound, firstly, the bottom of the first hydrogel layer 7 is fitted with a waterproof sleeve 15 and then locked in place with the assembly hole 6. Then, the liquid solution that works with the first hydrogel layer 7 is added into the reservoir 5. Then, the first cap 8 is assembled and fixed to the shell 1. The shell 1 is then attached to the wound on the patient's skin through the adhesive layer 2 at the bottom. Then, the device is turned on. After the first electrode patch 4 and the second electrode patch 81 are energized, they supply power to the first hydrogel layer 7. The conductive first hydrogel layer 7 can accelerate the release of the drug. At the same time, the skin wound will also be electrically stimulated, which will accelerate the healing of the wound.

[0036] Example 2

[0037] Please see Figure 6 , Figure 7 and Figure 8The technical solution provided by this utility model differs from the technical solution in Embodiment 1 in that: a second hydrogel layer 14 is assembled in the assembly hole 6 of the shell 1. The thickness of the second hydrogel layer 14 is less than that of the first hydrogel layer 7. The second hydrogel layer 14 is mainly composed of a top hydrogel dressing layer and a bottom photocatalyst bactericidal layer. The hydrogel dressing layer can penetrate downwards. Compared with the first hydrogel layer 7, its conductivity is poor, but a photocatalyst bactericidal layer is provided. By irradiating the second hydrogel layer 14 with light, the photocatalyst bactericidal layer can continuously sterilize and inhibit bacteria on the wound, thereby improving the sterilization and bactericidal effect of the hydrogel dressing layer in the wound healing process.

[0038] The top of the housing 1 is detachably and fixedly fitted with a second cover 9 via a connecting assembly 10. An LED light 91 is fixedly fitted at the bottom of the second cover 9. The LED light 91 consists of an outer waterproof lamp cover and internally uniformly distributed LED light beads. By setting the LED light 91, continuous illumination can be provided to the second hydrogel layer 14 below. A second circuit board 92 and a second button battery 93 are embedded in the top of the second cover 91. The second button battery 93 supplies power to the second circuit board 92. The second circuit board 92 is electrically connected to the LED light 91. The second circuit board 92 is equipped with a rectification and filtering circuit, a constant current control circuit, and a protection circuit. By setting the second circuit board 92, continuous power supply can be provided to the LED light 91, so that it can maintain stable light emission during long-term use.

[0039] like Figure 7 and Figure 8 As shown, an auxiliary fixing ring 94 is fixedly connected to the bottom of the second cap 9. After the second cap 9 is assembled and fixed to the shell 1, the top of the second hydrogel layer 14 can be assisted in positioning by the auxiliary fixing ring 94, which improves the stability of the second hydrogel layer 14 in the liquid storage cavity 5. At the same time, there is a certain gap between the bottom of the auxiliary fixing ring 94 and the bottom of the liquid storage cavity 5, which will not affect the supply of medicine to the second hydrogel layer 14 in the liquid storage cavity 5.

[0040] Working principle: When antibacterial and bactericidal effects are required during wound healing, the second hydrogel layer 14 and the waterproof sleeve 15 are snapped together and assembled into the liquid storage cavity 5. A drug solution matching the second hydrogel layer 14 is added into the liquid storage cavity 5. The second cap 9 is connected and fixed to the shell 1. Then, the shell 1 is attached to the wound on the skin through the adhesive layer 2. During the wound healing and repair process, the second hydrogel layer 14 turns on the LED light 91, which can enable the second hydrogel layer 14 to continuously inhibit and kill bacteria during wound healing.

Claims

1. A controlled-release patch for wound healing, comprising a shell (1), characterized in that, An adhesive layer (2) is fixedly mounted on the bottom of the housing (1). An assembly groove (3) is opened on the bottom of the housing (1). A first electrode patch (4) is fixedly mounted in the assembly groove (3). A liquid storage cavity (5) is opened on the top of the housing (1). An assembly hole (6) is opened at the bottom of the liquid storage cavity (5). A first hydrogel layer (7) is snapped into the assembly hole (6). A first cap (8) is mounted on the top of the housing (1). A connecting component (10) is assembled between the housing (1) and the first cap (8). A male connector (12) is fixedly mounted on the bottom of the first cap (8). A female connector (13) is embedded in the housing (1). The positions of the male connector (12) and the female connector (13) correspond to each other.

2. The controlled-release patch for wound healing according to claim 1, characterized in that: The bottom of the first cover (8) is fixedly fitted with a second electrode patch (81), and the top of the first cover (8) is embedded with a first circuit board (82) and a first button battery (83).

3. The controlled-release patch for wound healing according to claim 1, characterized in that: The connecting assembly (10) includes a connecting shaft (101), which is fixedly connected to the bottom of the first cover (8). A connecting hole (102) is provided on the top of the housing (1), and a magnet block (103) is fixedly assembled at the bottom of the connecting hole (102).

4. The controlled-release patch for wound healing according to claim 1, characterized in that: A waterproof sleeve (15) is fitted between the first hydrogel layer (7) and the assembly hole (6).

5. A controlled-release patch for wound healing according to claim 1, characterized in that: The sidewalls of the housing (1) are provided with opening slots (11) symmetrically on the left and right sides.

6. A controlled-release patch for wound healing according to claim 1, characterized in that: The assembly hole (6) is fitted with a second hydrogel layer (14), and the top of the housing (1) is detachably and fixedly connected to a second cap (9) via a connecting assembly (10).

7. A controlled-release patch for wound healing according to claim 6, characterized in that: An LED light (91) is fixedly mounted on the bottom of the second cover (9), and a second circuit board (92) and a second button battery (93) are embedded in the top of the second cover (9).

8. A controlled-release patch for wound healing according to claim 6, characterized in that: The bottom of the second cover (9) is fixedly fitted with an auxiliary fixing ring (94).

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