A device for preparing small platelet-rich plasma based on membrane filtration fractionation
Patent Information
- Application Number
- CN202522202660.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-17
- Publication Date
- 2026-10-20
- Estimated Expiration
- 2035-10-17
AI Technical Summary
[0003]而在富血小板血浆制备的时候需要将血液注入至制备装置内部,而在注入的时候还需要搭配散气孔对制备机构内部进行气体平衡,而在离心的时候需要对血液注入管和散气管机芯进行密封,而现有的密封装置在使用的时候仅仅是通过利用橡胶带连接的橡胶塞进行密封,而这样的密封方式打开之后容易因为自身的弹性而位置变化,导致其影响到注入针管的正常血液注入,并且在富血小板血浆制备完成之后还需要对其进行抽取,而如果离心之后的富血小板血浆存量较少的话或者抽取针管插入倾斜的话则极易影响到抽取质量,为此,我们提出一种基于膜过滤分级分离的富小血板血浆制备装置
[0011]与现有技术相比,本实用新型具有以下有益效果:本实用新型设置的血液注入管可以将血液注入至制备机构内部,而在血液注入的时候设置的散气管则可以对制备机构内部进行气体平衡,随后设置的密封机构可以对血液注入管和散气管进行密封,并且在密封机构打开之后防止其影响到注入针管的正常使用,而设置的辅助抽取机构可以保证抽取针管可以垂直插入至制备机构内部对富血小板血浆抽取,并且可以调整抽取针管的伸入长度,防止对贫血小板血浆和红细胞抽取。
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Figure CN224864967U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of platelet-rich plasma preparation technology, specifically a platelet-rich plasma preparation device based on membrane filtration and graded separation. Background Technology
[0002] Platelet-rich plasma (PRP) is a platelet concentrate obtained by centrifuging autologous whole blood. Because platelets contain various growth factors, PRP is widely used to promote tissue repair and regeneration, showing potential in multiple medical fields. During centrifugation, PRP is processed by using filter membranes of different pore sizes, utilizing the differences in size and physical properties between blood cells (red blood cells, white blood cells, and platelets) and plasma to achieve stepwise separation.
[0003] In the preparation of platelet-rich plasma (PRP), blood needs to be injected into the preparation device. During injection, a vent is required to balance the gas inside the device. During centrifugation, the blood injection tube and the vent mechanism need to be sealed. However, existing sealing devices simply use rubber plugs connected by rubber bands. This type of seal is prone to displacement due to its elasticity, which can affect the normal blood injection through the injection needle. Furthermore, after PRP preparation is complete, it needs to be extracted. If the amount of PRP remaining after centrifugation is low, or if the extraction needle is inserted at an angle, the extraction quality can be easily affected. Therefore, we propose a PRP preparation device based on membrane filtration and graded separation. Utility Model Content
[0004] The purpose of this invention is to provide a platelet-rich plasma preparation device based on membrane filtration and graded separation, so as to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, this utility model provides the following technical solution: a platelet-rich plasma preparation device based on membrane filtration and graded separation, comprising a preparation mechanism for preparing platelet-rich plasma, a blood injection tube for blood injection being provided through one side of the preparation mechanism, a gas dispersing tube for gas balance inside the preparation mechanism being provided on the other side of the preparation mechanism, a rubber stopper being provided through the top of the preparation mechanism, a sealing mechanism for sealing the blood injection tube and the gas dispersing tube being provided on the outside of the preparation mechanism, and an auxiliary extraction mechanism for facilitating the positioning of the extraction needle being provided on the top of the preparation mechanism.
[0006] Furthermore, the preparation mechanism includes a first preparation chamber, a second preparation chamber, and a third preparation chamber, which are interconnected, and a rubber stopper is provided through the top of the first preparation chamber.
[0007] Furthermore, the auxiliary extraction mechanism includes an internally threaded tube, a threaded locking tube, a limiting tube, and a bottom support tube. An internally threaded tube is fixedly installed on the top of the first preparation chamber. The internally threaded tube is connected to a threaded locking tube. A limiting tube is provided through the inside of the threaded locking tube. The bottom of the limiting tube is connected to a frustum-shaped bottom support tube.
[0008] Furthermore, the sealing mechanism includes a support block, a fixed shaft, a rubber belt, a sealing plug, and a retrieval block. Two sets of arc-shaped support blocks are fixedly connected to the outside of the first preparation chamber. A rubber belt is installed on the support block through the fixed shaft. A sealing plug for sealing the blood injection tube and the gas dispersing tube is provided on the rubber belt. A retrieval block is fixedly connected to one end of the sealing plug.
[0009] Furthermore, the sealing mechanism also includes a blocking rod and a blocking groove. Blocking rods are fixedly installed on both sides of the first preparation chamber, and an arc-shaped blocking groove is provided on the rubber belt at the position corresponding to the blocking rod.
[0010] Furthermore, the top of the first preparation chamber is bonded with an adhesive sealing sheet to seal the rubber plug.
[0011] Compared with the prior art, the present invention has the following beneficial effects: the blood injection tube provided by the present invention can inject blood into the preparation mechanism, and the gas dispersing tube provided during blood injection can balance the gas inside the preparation mechanism. The sealing mechanism provided thereafter can seal the blood injection tube and the gas dispersing tube, and prevent the injection needle from being affected after the sealing mechanism is opened. The auxiliary extraction mechanism provided can ensure that the extraction needle can be inserted vertically into the preparation mechanism to extract platelet-rich plasma, and the insertion length of the extraction needle can be adjusted to prevent the extraction of anemic platelet-rich plasma and red blood cells. Attached Figure Description
[0012] Figure 1 This is a first perspective structural diagram of the present invention;
[0013] Figure 2 This is a second perspective view of the structure of this utility model;
[0014] Figure 3 This is a three-dimensional structural schematic diagram of the auxiliary extraction mechanism of this utility model;
[0015] Figure 4 This is an enlarged schematic diagram of structure A of this utility model.
[0016] In the figure: 1. Preparation mechanism, 2. Blood injection tube, 3. Gas dispersing tube, 4. Sealing mechanism, 5. Rubber plug, 6. Auxiliary extraction mechanism, 7. First preparation chamber, 8. Second preparation chamber, 9. Third preparation chamber, 10. Internal threaded tube, 11. Threaded locking tube, 12. Limiting tube, 13. Bottom support tube, 14. Support block, 15. Fixed shaft, 16. Rubber belt, 17. Sealing plug, 18. Removal block, 19. Blocking rod, 20. Blocking groove, 21. Adhesive sealing sheet. Detailed Implementation
[0017] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0018] Please see Figures 1-4 This utility model provides a technical solution: a platelet-rich plasma preparation device based on membrane filtration and graded separation, including a preparation mechanism 1 for preparing platelet-rich plasma, a blood injection tube 2 for blood injection through one side of the preparation mechanism 1, a gas dissipation tube 3 for gas balance inside the preparation mechanism 1 through the other side of the preparation mechanism 1, a rubber stopper 5 through the top of the preparation mechanism 1, a sealing mechanism 4 for sealing the blood injection tube 2 and the gas dissipation tube 3 outside the preparation mechanism 1, and an auxiliary extraction mechanism 6 for facilitating the positioning of the extraction needle at the top of the preparation mechanism 1.
[0019] The blood injection tube 2 injects blood into the preparation mechanism 1. During blood injection, the gas dispersing tube 3 balances the gas inside the preparation mechanism 1. The sealing mechanism 4 seals the blood injection tube 2 and the gas dispersing tube 3 and prevents them from affecting the normal use of the injection needle after the sealing mechanism 4 is opened. The auxiliary extraction mechanism 6 ensures that the extraction needle can be inserted vertically into the preparation mechanism 1 through the rubber stopper 5 to extract platelet-rich plasma. The insertion length of the extraction needle can be adjusted to prevent the extraction of anemic platelet-rich plasma and red blood cells.
[0020] Please see Figures 1-2 The preparation mechanism 1 includes a first preparation chamber 7, a second preparation chamber 8, and a third preparation chamber 9, which are interconnected. A rubber stopper 5 is provided through the top of the first preparation chamber 7.
[0021] The first preparation chamber 7, the second preparation chamber 8, and the third preparation chamber 9 are configured to store platelet-rich plasma, platelet-poor plasma, and red blood cells after centrifugation. Subsequently, an external extraction needle can be inserted into the first preparation chamber 7 through a rubber stopper 5 to extract platelet-rich plasma.
[0022] Please see Figure 1 , Figure 2 and Figure 3 The auxiliary extraction mechanism 6 includes an internally threaded tube 10, a threaded locking tube 11, a limiting tube 12, and a bottom support tube 13. The internally threaded tube 10 is fixedly installed on the top of the first preparation chamber 7. The internally threaded tube 10 is internally threaded to the threaded locking tube 11. The limiting tube 12 is provided through the inside of the threaded locking tube 11. The bottom of the limiting tube 12 is connected to the frustum-shaped bottom support tube 13.
[0023] After the platelet-rich plasma is prepared by centrifugation, the threaded locking tube 11 is threadedly connected to the internal threaded tube 10 according to the height of the platelet-rich plasma after centrifugation. The position between the internal threaded tube 10 and the threaded locking tube 11 can be adjusted, thereby controlling the insertion length of the extraction needle. The extraction needle can be limited by the limiting tube 12 and the frustum-shaped bottom support tube 13, so that the extraction needle can enter vertically.
[0024] Please see Figure 1 , Figure 2 and Figure 4 The sealing mechanism 4 includes a support block 14, a fixed shaft 15, a rubber belt 16, a sealing plug 17, and a take-up block 18. Two sets of arc-shaped support blocks 14 are fixedly connected to the outside of the first preparation chamber 7. A rubber belt 16 is installed on the support block 14 through the fixed shaft 15. A sealing plug 17 is provided on the rubber belt 16 to seal the blood injection tube 2 and the gas dispersing tube 3. One end of the sealing plug 17 is fixedly connected to the take-up block 18. The sealing mechanism 4 also includes a blocking rod 19 and a blocking groove 20. Blocking rods 19 are fixedly installed on both sides of the first preparation chamber 7. An arc-shaped blocking groove 20 is opened on the rubber belt 16 at the position corresponding to the blocking rod 19.
[0025] The rubber band 16 is positioned by the support block 14 and the fixed shaft 15. The sealing plug 17 then seals the blood injection tube 2 and the gas dissipation tube 3. When it is necessary to open the blood injection tube 2 and the gas dissipation tube 3, the take-up block 18 is pulled to disengage the sealing plug 17 from the blood injection tube 2 and the gas dissipation tube 3. Then, the blocking groove 20 on the rubber band 16 is positioned on the blocking rod 19 to prevent the rubber band 16 and the sealing plug 17 from falling due to elasticity and affecting the blood injection of the injection needle and the normal gas dissipation of the gas dissipation tube 3.
[0026] Please see Figure 2 The top of the first preparation chamber 7 is bonded with an adhesive sealing sheet 21 to seal the rubber stopper 5. The adhesive sealing sheet 21 can ensure that the rubber stopper 5 can be sealed during centrifugation to prevent contamination.
[0027] In use, firstly, the blood injection tube 2 injects blood into the preparation mechanism 1. During blood injection, the gas dispersing tube 3 balances the gas inside the preparation mechanism 1. Then, the sealing mechanism 4 seals the blood injection tube 2 and the gas dispersing tube 3, preventing interference with the normal use of the injection needle after the sealing mechanism 4 is opened. The auxiliary extraction mechanism 6 ensures that the extraction needle can be inserted vertically through the rubber stopper 5 into the preparation mechanism 1 to extract platelet-rich plasma, and the insertion length of the extraction needle can be adjusted to prevent the extraction of anemic platelet-rich plasma and red blood cells. The first preparation chamber 7, the second preparation chamber 8, and the third preparation chamber 9 store platelet-rich plasma, anemic platelet-rich plasma, and red blood cells after centrifugation. Subsequently, an external extraction needle can be inserted through the rubber stopper 5 into the first preparation chamber 7 to extract platelet-rich plasma. After the platelet-rich plasma is centrifuged... After centrifugation, the threaded locking tube 11 is threadedly connected to the internal threaded tube 10 according to the height of the platelet-rich plasma. The position between the internal threaded tube 10 and the threaded locking tube 11 can be adjusted, thereby controlling the insertion length of the extraction needle. The extraction needle can be limited by the limiting tube 12 and the frustum-shaped bottom support tube 13, allowing the extraction needle to enter vertically. The rubber band 16 is positioned by the support block 14 and the fixed shaft 15. The sealing plug 17 then seals the blood injection tube 2 and the air diffuser tube 3. When it is necessary to open the blood injection tube 2 and the air diffuser tube 3, the take-up block 18 is pulled to disengage the sealing plug 17 from the blood injection tube 2 and the air diffuser tube 3. Then, the blocking groove 20 on the rubber band 16 is positioned on the blocking rod 19 to prevent the rubber band 16 and the sealing plug 17 from falling due to elasticity and affecting the blood injection of the injection needle and the normal air diffusion of the air diffuser tube 3.
[0028] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A platelet-rich plasma preparation device based on membrane filtration and graded separation, comprising a preparation mechanism (1) for preparing platelet-rich plasma, wherein a blood injection tube (2) for blood injection is provided through one side of the preparation mechanism (1), and a gas dissipation tube (3) for gas balance inside the preparation mechanism (1) is provided on the other side of the preparation mechanism (1), characterized in that: A rubber stopper (5) is provided through the top of the preparation mechanism (1), a sealing mechanism (4) for sealing the blood injection tube (2) and the gas dispersing tube (3) is provided on the outside of the preparation mechanism (1), and an auxiliary extraction mechanism (6) is provided on the top of the preparation mechanism (1) to facilitate the positioning of the extraction needle tube.
2. The platelet-rich plasma preparation device based on membrane filtration and graded separation according to claim 1, characterized in that: The preparation mechanism (1) includes a first preparation chamber (7), a second preparation chamber (8) and a third preparation chamber (9), which are interconnected. A rubber stopper (5) is provided through the top of the first preparation chamber (7).
3. The platelet-rich plasma preparation device based on membrane filtration and graded separation according to claim 2, characterized in that: The auxiliary extraction mechanism (6) includes an internal threaded tube (10), a threaded locking tube (11), a limiting tube (12), and a bottom support tube (13). The top of the first preparation chamber (7) is fixedly installed with an internal threaded tube (10). The internal threaded tube (10) is connected to the threaded locking tube (11) by its internal thread. The limiting tube (12) is provided through the inside of the threaded locking tube (11). The bottom of the limiting tube (12) is connected to a frustum-shaped bottom support tube (13).
4. The platelet-rich plasma preparation device based on membrane filtration and graded separation according to claim 3, characterized in that: The sealing mechanism (4) includes a support block (14), a fixed shaft (15), a rubber belt (16), a sealing plug (17), and a take-up block (18). Two sets of arc-shaped support blocks (14) are fixedly connected to the outside of the first preparation chamber (7). A rubber belt (16) is installed on the support block (14) through the fixed shaft (15). A sealing plug (17) for sealing the blood injection tube (2) and the gas dispersing tube (3) is provided on the rubber belt (16). A take-up block (18) is fixedly connected to one end of the sealing plug (17).
5. The platelet-rich plasma preparation device based on membrane filtration and graded separation according to claim 4, characterized in that: The sealing mechanism (4) also includes a blocking rod (19) and a blocking groove (20). The blocking rod (19) is fixedly installed on both sides of the first preparation chamber (7). An arc-shaped blocking groove (20) is opened on the rubber belt (16) at the position corresponding to the blocking rod (19).
6. The platelet-rich plasma preparation device based on membrane filtration and graded separation according to claim 5, characterized in that: The top of the first preparation chamber (7) is bonded with an adhesive sealing sheet (21) that seals the rubber plug (5).