A kit for preparing platelet-rich plasma

Abstract

The utility model belongs to platelet rich plasma preparation technical field relates to a kind of set of platelet rich plasma preparation, comprising: syringe assembly is by syringe core stem, the syringe core stem piston of being sleeved in the front end of core stem and syringe outer sleeve structure, and syringe core stem and syringe core stem piston are located in the inner chamber of syringe outer sleeve;Syringe outer sleeve front end is fixed with syringe liquid outlet pipe and the syringe connecting pipe with internal thread;Syringe connecting pipe is located in the outside of syringe liquid outlet pipe;Centrifugal tube assembly, including hollow bottom closed centrifugal tube core stem, the centrifugal tube piston of being sleeved in the front end of core stem, centrifugal tube and tube cap, and centrifugal tube core stem bottom is equipped with the core stem connecting pipe with external thread;Centrifugal tube front end is fixed with centrifugal tube liquid outlet pipe and the tube cap connecting pipe with internal thread;Tube cap and tube cap connecting pipe are threadedly connected.The syringe of the application is directly connected with centrifugal tube by thread, without additional adapter or open transfer step, reduce liquid exposure risk.

Description

Technical Field

[0001] This utility model relates to the field of platelet-rich plasma preparation technology, and in particular to a kit for preparing platelet-rich plasma. Background Technology

[0002] Platelet-rich plasma (PRP) is a high-concentration plasma separated from autologous blood using centrifugation technology. Rich in growth factors that promote tissue repair, it has important clinical applications in orthopedics, wound care, and aesthetic medicine. The preparation of PRP requires strict adherence to aseptic techniques, ease of operation, and separation efficiency; however, existing technologies generally suffer from complex procedures and low standardization, hindering its clinical adoption.

[0003] Traditional PRP preparation requires manual transfer of blood to centrifuge tubes after syringe collection, involving multiple openings of the liquid passage and increasing the risk of contamination. Connecting the centrifuge tubes to the syringe often requires external adapters or tubing, resulting in poor sealing and cumbersome operation. Furthermore, the interface between red blood cells and PRP becomes blurred after centrifugation, making it easy for impurities to enter or for valuable components to be lost during extraction, leading to insufficient separation accuracy. Existing centrifuge tubes have a simple structure, lacking targeted design for the stratification characteristics of PRP, and lack corresponding graduation markings. Operators must rely on experience to adjust centrifugation parameters and liquid volume, making it difficult to ensure batch-to-batch stability.

[0004] While some improvements have attempted to optimize the connection between centrifuge tubes and syringes (such as snap-fit ​​or plug-in structures), these designs are prone to leakage or interface detachment due to improper operation, and they do not address the core issue of unclear layer interfaces. Some solutions add liquid channels, but these are not linked to the piston structure, requiring manual adjustment of the piston position after centrifugation to align with the interface, resulting in redundant operation steps. Furthermore, existing equipment generally neglects anti-slip and ergonomic design, making it easy for hands to slip and cause errors in aseptic operating environments, further impacting preparation efficiency and safety.

[0005] Therefore, there is an urgent need for an integrated, high-precision PRP preparation kit that achieves seamless connection between syringe and centrifuge tube, precise positioning of the layered interface, and standardization of the operation process through structural innovation. This would simplify the steps, improve separation purity, and reduce the risk of contamination, thus meeting the dual clinical needs for both the quality of PRP preparation and ease of operation. Utility Model Content

[0006] To address the problems mentioned in the background art, this utility model provides a kit for preparing platelet-rich plasma. The syringe and centrifuge tube are directly connected by threads, eliminating the need for additional adapters or open transfer steps and reducing the risk of liquid exposure. The connecting tube and the outlet tube adopt an inner and outer nested design to ensure interface sealing and prevent leakage or contamination, making it particularly suitable for aseptic operating environments.

[0007] The technical solution adopted by this utility model to solve its technical problem is as follows: A kit for preparing platelet-rich plasma is provided, comprising: a syringe assembly, consisting of a syringe rod, a syringe rod piston sleeved at the front end of the rod, and a syringe outer sleeve; the syringe rod and syringe rod piston are located within the inner cavity of the syringe outer sleeve; a syringe outlet tube and a syringe connecting tube with internal threads are fixed to the front end of the syringe outer sleeve; the syringe connecting tube is located outside the syringe outlet tube; a centrifuge tube assembly, comprising a hollow, bottom-closed centrifuge tube rod, a centrifuge tube piston sleeved at the front end of the rod, a centrifuge tube, and a tube cap; a rod connecting tube with external threads is provided at the bottom of the centrifuge tube rod, and the syringe connecting tube and the rod connecting tube form a detachable threaded fit; a centrifuge tube outlet tube and a tube cap connecting tube with internal threads are fixed to the front end of the centrifuge tube; the tube cap connecting tube is located outside the centrifuge tube outlet tube; the tube cap and the tube cap connecting tube are threadedly connected.

[0008] Furthermore, the hollow bottom of the centrifuge tube core rod extends radially towards the side wall to form a centrifuge tube core rod outlet pipe; a groove is provided at the end of the centrifuge tube core rod that connects to the centrifuge tube core rod piston; the centrifuge tube core rod piston has a conical hollow structure, and a through hole is provided on the side wall of the centrifuge tube core rod piston at a position corresponding to the centrifuge tube core rod outlet pipe; a protrusion adapted to the groove is provided above the through hole to prevent the centrifuge tube core rod piston from rotating.

[0009] Furthermore, the cap includes a fixing plate, an inner cylinder, and an outer cylinder; both the inner and outer cylinders are fixedly connected to the fixing plate; the inner cylinder is located between the outer cylinders; the outer side wall of the inner cylinder is provided with external threads for threaded connection with the centrifugal tube.

[0010] Furthermore, the outer wall of the outer cylinder is provided with circumferentially spaced wavy anti-slip ridges.

[0011] Furthermore, the pressing end of the syringe plunger is provided with axially extending anti-slip grooves.

[0012] Furthermore, corresponding graduation lines are provided on the syringe jacket and the side wall of the centrifuge tube.

[0013] Compared with the prior art, the beneficial effects of this utility model are:

[0014] (1) The syringe and centrifuge tube of this utility model are directly connected by threads, without the need for additional adapters or open transfer steps, reducing the risk of liquid exposure; the connecting tube and the outlet tube adopt an inner and outer nested design to ensure the interface is sealed and avoid leakage or contamination, which is especially suitable for aseptic operating environments.

[0015] (2) The centrifuge tube piston of this utility model is provided with a through hole and a slot matching structure to ensure that the liquid channel automatically aligns with the red blood cell-PRP interface after centrifugation; the lower layer of red blood cells can be directly extracted through the core tube outlet pipe, and the operator can use the scale line to accurately control the extraction volume, avoid impurities or loss of effective components, and ensure the purity and concentration of PRP.

[0016] (3) The syringe and centrifuge tube of this utility model are equipped with scale lines on the side wall. Combined with the blood collection volume and anticoagulant ratio of different specification kits (BP-I / II / III), the liquid volume can be accurately controlled. The centrifugation parameters are clear, reducing reliance on human experience and ensuring the stability of PRP preparation in different batches, thus meeting the needs of large-scale clinical application.

[0017] (4) The anti-slip texture at the end of the syringe plunger and the wavy ridge on the outer cylinder of the cap enhance the friction during operation and prevent hand slippage; the anti-rotation structure of the centrifuge tube plunger piston and plunger prevents liquid channel displacement and simplifies the adjustment steps after centrifugation. The overall design reduces the rate of operational errors, shortens the preparation time, and improves the work efficiency of medical staff. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the structure of a platelet-rich plasma preparation kit according to the present invention;

[0019] Figure 2 This is a schematic diagram of the split structure of a platelet-rich plasma preparation kit according to this utility model;

[0020] Figure 3 This is a schematic diagram of the syringe core rod of a kit for preparing platelet-rich plasma according to this utility model;

[0021] Figure 4 This is a schematic diagram of the centrifuge tube core rod of a kit for preparing platelet-rich plasma according to this utility model;

[0022] Figure 5 This is a schematic diagram of the centrifuge tube structure of a set for preparing platelet-rich plasma according to this utility model;

[0023] Figure 6 This is a schematic diagram of the syringe jacket of a kit for preparing platelet-rich plasma according to this utility model;

[0024] Figure 7 This is a schematic diagram of the cap structure of a set for preparing platelet-rich plasma according to this utility model;

[0025] Figure 8 This is a schematic diagram of the centrifuge tube core rod piston of a set for preparing platelet-rich plasma according to this utility model;

[0026] The components in the attached diagram are labeled as follows: 1. Syringe assembly; 11. Syringe core rod; 12. Syringe core rod piston; 13. Syringe outer sleeve; 14. Syringe outlet tube; 15. Syringe connecting tube; 2. Centrifuge tube assembly; 21. Centrifuge tube core rod; 22. Centrifuge tube core rod piston; 23. Centrifuge tube; 24. Tube cap; 25. Centrifuge tube outlet tube; 26. Tube cap connecting tube; 27. Centrifuge tube core rod outlet tube; 28. Slot; 29. ​​Through hole; 30. Protrusion; 241. Fixing plate; 242. Inner cylinder; 243. Outer cylinder; 244. Anti-slip ridge; 111. Anti-slip texture. Detailed Implementation

[0027] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present utility model.

[0028] Example:

[0029] like Figures 1 to 3 As shown, this embodiment provides a platelet-rich plasma (PRP) preparation kit, comprising: a syringe assembly 1 consisting of a syringe plunger 11, a syringe plunger piston 12 sleeved at the front end of the plunger, and a syringe outer sleeve 13. The syringe plunger 11 and piston 12 are located within the inner cavity of the syringe outer sleeve 13. The front end of the syringe outer sleeve 13 is provided with a syringe outlet tube 14 and a syringe connecting tube 15 with internal threads, the connecting tube 15 being located outside the outlet tube 14. The pressing end of the syringe plunger 11 is provided with axially extending anti-slip grooves 111 for easy application of force during operation. The side wall of the syringe outer sleeve 13 is marked with graduation lines for precise control of blood collection volume and anticoagulant dosage.

[0030] Centrifuge tube assembly 2 includes a hollow, bottom-sealed centrifuge tube core rod 21, a centrifuge tube core rod piston 22 sleeved at the front end of the core rod, a centrifuge tube 23, and a tube cap 24. The bottom of the centrifuge tube core rod 21 has a core rod connecting tube with external threads, and a syringe connecting tube 14 forms a detachable threaded connection with the core rod connecting tube. The front end of the centrifuge tube 23 is fixed with a centrifuge tube outlet tube 25 and a tube cap connecting tube 26 with internal threads. The tube cap connecting tube 26 is located outside the centrifuge tube outlet tube 25. The tube cap 24 is threadedly connected to the tube cap connecting tube 26. The core rod core rod 21 has an externally threaded core rod connecting tube at its bottom, which can achieve a sealed connection with the syringe connecting tube 15 through a threaded engagement. The front end of the centrifuge tube 23 has a centrifuge tube outlet tube 25 and a tube cap connecting tube 26 with internal threads, and the tube cap 24 seals the tube cap connecting tube 26 through a threaded connection.

[0031] Furthermore, a centrifuge tube core rod 21 has a hollow bottom extending radially to provide a centrifuge tube core rod outlet pipe 27, and a groove 28 is provided at the connection end between the core rod and the piston 22. The side wall of the centrifuge tube core rod piston 22 has a through hole 29 corresponding to the outlet pipe 27, and a protrusion 30 adapted to the groove 28 is provided above the through hole to prevent the piston from rotating.

[0032] Furthermore, the cap 24 includes a fixing plate 241, an inner cylinder 242 and an outer cylinder 243. The outer wall of the inner cylinder 242 is provided with external threads to connect the centrifuge tube 23, and the outer wall of the outer cylinder 243 is provided with wavy anti-slip ridges 244 to facilitate screwing operation.

[0033] Furthermore, the hollow bottom of the centrifuge tube core rod 21 extends radially towards the side wall to provide a centrifuge tube core rod outlet pipe 27; a groove 28 is provided at the end of the centrifuge tube core rod 21 that connects to the centrifuge tube core rod piston 22; the centrifuge tube core rod piston 22 has a conical hollow structure, and a through hole 29 is provided on the side wall of the centrifuge tube core rod piston 22 at a position corresponding to the centrifuge tube core rod outlet pipe 27; a protrusion 30 is provided above the through hole 29 that matches the groove 28, which is used to prevent the centrifuge tube core rod piston 22 from rotating.

[0034] Furthermore, the syringe jacket 13 and the side wall of the centrifuge tube 23 are provided with corresponding graduation lines to control the liquid volume.

[0035] Specific operational steps for preparing platelet-rich plasma:

[0036] Step 1: Anticoagulated blood collection. Select the BP-I kit, collect 18ml of blood, and add 2ml of anticoagulant. Use a syringe to draw 2ml of ACD-A anticoagulant, ensuring it thoroughly wets the inside of the syringe. Draw 18ml of blood from the median cubital vein, gently shaking the syringe to mix the blood and anticoagulant thoroughly.

[0037] Step 2: Blood Transfer and First Centrifugation. Connect the syringe connecting tube 15 to the centrifuge tube core connecting tube via threads. Slowly push the syringe core 11 to transfer the mixture into the centrifuge tube 23. Tighten the cap 24 and place the centrifuge tube into the centrifuge. Take another centrifuge tube, inject an equal volume of physiological saline as a balancing tube, place them symmetrically, and start the centrifuge. First centrifugation parameters: speed 1730 r / min, time 10 minutes 30 seconds.

[0038] Step 3: Remove the red blood cell layer. After centrifugation, the liquid in the centrifuge tube separates into three layers: an upper plasma layer, a middle PRP layer, and a lower red blood cell layer. Connect the syringe to the centrifuge tube outlet tube 25, slowly pull the core rod 11, and draw the lower red blood cells to 3-5 mm below the interface and discard them. Replace with a new cap 24 and seal the centrifuge tube.

[0039] Step 4: Second centrifugation. Shake the remaining liquid in the centrifuge tube to mix well. Place the centrifuge tube and the equilibration tube symmetrically again, and drain an equal amount of physiological saline from the equilibration tube. Second centrifugation parameters: speed 20-30 r / min, time 10 minutes and 30 seconds.

[0040] Step 5: Extract PRP. After centrifugation, the upper layer is platelet-rich plasma (PPP), and the lower layer is PRP. Pull the core rod through the core rod outlet tube 27 of the centrifuge tube 21 to discard the supernatant PPP until the required volume of PRP remains. Shake the PRP well and set aside.

[0041] The syringe and centrifuge tube of this invention are directly connected by threads, eliminating the need for additional adapters or open transfer steps and reducing the risk of liquid exposure. The connecting tube and the outlet tube adopt an inner and outer nested design to ensure the interface is sealed and avoid leakage or contamination, making it especially suitable for aseptic operating environments.

[0042] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A kit for preparing platelet-rich plasma, characterized in that, include: The syringe assembly (1) consists of a syringe rod (11), a syringe rod piston (12) sleeved on the front end of the syringe rod, and a syringe outer sleeve (13). The syringe rod (11) and the syringe rod piston (12) are located in the inner cavity of the syringe outer sleeve (13). The syringe jacket (13) has a syringe outlet tube (14) and a syringe connecting tube (15) with internal threads fixed at the front end; the syringe connecting tube (15) is located outside the syringe outlet tube (14); The centrifuge tube assembly (2) includes a hollow, bottom-closed centrifuge tube core rod (21), a centrifuge tube core rod piston (22) sleeved on the front end of the core rod, a centrifuge tube (23) and a tube cap (24). The bottom of the centrifuge tube core rod (21) is provided with a core rod connecting tube with external threads. The syringe connecting tube (15) and the core rod connecting tube form a detachable threaded fit. The centrifuge tube (23) is fixed with a centrifuge tube outlet tube (25) and a tube cap connecting tube (26) with internal threads at the front end; the tube cap connecting tube (26) is located on the outside of the centrifuge tube outlet tube (25); The cap (24) is threadedly connected to the cap connecting pipe (26).

2. The platelet-rich plasma preparation kit according to claim 1, characterized in that: The hollow bottom of the centrifuge tube core rod (21) extends radially toward the side wall and is provided with a centrifuge tube core rod outlet pipe (27). The centrifuge tube core rod (21) is connected to the centrifuge tube core rod piston (22) at one end with a groove (28); The centrifuge tube core rod piston (22) has a conical hollow structure. A through hole (29) is provided on the side wall of the centrifuge tube core rod piston (22) at the position corresponding to the centrifuge tube core rod outlet pipe (27). A protrusion (30) is provided above the through hole (29) to match the slot (28) and to prevent the centrifuge tube core rod piston (22) from rotating.

3. The platelet-rich plasma preparation kit according to claim 1, characterized in that: The cap (24) includes a fixing plate (241), an inner cylinder (242) and an outer cylinder (243); the inner cylinder (242) and the outer cylinder (243) are both fixedly connected to the fixing plate (241); the inner cylinder (242) is located between the outer cylinder (243); the outer side wall of the inner cylinder (242) is provided with external threads for threaded connection with the centrifuge tube (23).

4. The platelet-rich plasma preparation kit according to claim 1, characterized in that: The outer wall of the outer cylinder (243) is provided with circumferentially spaced wavy anti-slip ridges (244).

5. The platelet-rich plasma preparation kit according to claim 1, characterized in that: The pressing end of the syringe plunger (11) is provided with axially extending anti-slip texture (111).

6. The platelet-rich plasma preparation kit according to claim 1, characterized in that: The syringe jacket (13) and centrifuge tube (23) have corresponding graduation lines on their side walls.

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