A nano immunomagnetic bead washing device
Patent Information
- Application Number
- CN202521935780.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-09
- Publication Date
- 2026-10-20
- Estimated Expiration
- 2035-09-09
AI Technical Summary
在磁珠的制备工艺中,需要对磁珠进行洗涤,以确保磁珠的性能指标达标,然而,目前磁珠的洗涤过程繁琐,人力物力成本高
[0013]采用上述技术方案后,本实用新型与现有技术相比,具备以下优点:本实用新型一种纳米免疫磁珠洗涤装置,将磁珠溶液通过入料管通入洗涤腔内,并打开环形永磁体,磁珠溶液内的磁珠被吸附在环形凹槽内,打开喷头,喷头中喷出的水流再将环形凹槽内的磁珠冲离,完成对磁珠的洗涤,实现对磁珠的快速洗涤。
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Figure CN224865934U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of magnetic bead washing technology, specifically a nano-immune magnetic bead washing device. Background Technology
[0002] Magnetic composite microspheres and other nano-magnetic materials, when combined with non-magnetic materials such as organic polymers, biomacromolecules, and inorganic substances in specific structural phases or modified with functional groups, can yield various magnetic composite products, collectively referred to as "magnetic beads." The preparation process of magnetic beads requires a washing device to ensure their performance indicators meet standards. However, the current washing process for magnetic beads is cumbersome and incurs high labor and material costs.
[0003] This case arose in order to resolve the aforementioned issues. Utility Model Content
[0004] (a) Technical problems to be solved
[0005] The purpose of this invention is to provide a nano-immunomagnetic bead washing device to solve the problems mentioned in the background art.
[0006] (II) Technical Solution
[0007] To achieve the above objectives, this utility model provides the following technical solution: a nano-immunomagnetic bead washing device, comprising a washing tub, the washing tub being an inverted conical shape, the washing tub having an opening extending through its top and bottom, the washing tub having an inclined section and a vertical section on its side, the washing tub being composed of alternating vertical and inclined sections, a cleaning mechanism being inserted into the opening on the top of the washing tub, the cleaning mechanism comprising a cover plate and a cleaning cone, the cleaning cone also being an inverted conical shape, the cover plate being connected to the upper end face of the cleaning cone, and the edge of the cover plate being connected to the upper edge of the washing tub.
[0008] Preferably, the side of the washing cone is also provided with inclined sections and vertical sections spaced apart, and a gap is formed between the outer side of the washing cone and the inner side of the washing tub. The gap is also divided into inclined sections and vertical sections, and the gap is a washing chamber. A feed pipe is connected to the side of the washing tub, and the feed pipe is connected to the washing chamber.
[0009] Preferably, an annular groove is provided on the inclined steps on the inner side of the washing tub, and a nozzle is connected to the inclined section on the outer side of the washing cone, with the nozzle pointing vertically downward and located above the vertical section of the washing chamber.
[0010] Preferably, the upper end of the cover plate is connected to a water inlet pipe, and the cleaning cone is provided with a connecting water pipe, which connects the water inlet pipe and the nozzle.
[0011] Preferably, the outer side of the washing tub is provided with an annular permanent magnet, which is located on the outer side of the inclined section.
[0012] (III) Beneficial Effects
[0013] After adopting the above technical solution, the present invention has the following advantages compared with the prior art: The present invention provides a nano-immunomagnetic bead washing device, in which a magnetic bead solution is introduced into the washing chamber through the feed pipe, and the annular permanent magnet is opened. The magnetic beads in the magnetic bead solution are adsorbed into the annular groove. The nozzle is opened, and the water flow sprayed from the nozzle washes away the magnetic beads in the annular groove, thus completing the washing of the magnetic beads and achieving rapid washing of the magnetic beads. Attached Figure Description
[0014] Figure 1 This is a schematic diagram of the present invention;
[0015] Figure 2 This is a cross-sectional schematic diagram of the present invention;
[0016] In the diagram: 1. Washing tub, 2. Cover plate, 3. Washing cone, 4, 5. Washing chamber, 6. Feed pipe, 7. Annular groove, 8. Nozzle, 9. Water inlet pipe, 10. Annular permanent magnet. Detailed Implementation
[0017] The present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be noted that the proportions shown in the drawings are not exactly the same as the actual proportions and are used as examples only.
[0018] This utility model provides a nano-immunomagnetic bead washing device, such as... Figure 1-2 As shown, the washing tub 1 is an inverted conical barrel shape with openings running through it from top to bottom. The sides of the washing tub 1 have alternating inclined and vertical sections. A cleaning mechanism is inserted into the opening at the top of the washing tub 1. The cleaning mechanism includes a cover plate 2 and a cleaning cone 3, which is also an inverted conical barrel shape (the inner side of the washing tub 1 and the outer side of the cleaning cone 3 are parallel). The cover plate 2 is connected to the upper end face of the cleaning cone 3, and the edge of the cover plate 2 is connected to the upper edge of the washing tub 1. A water inlet pipe 9 is connected to the upper end of the cover plate 2. A connecting water pipe (with a connected water passage) is provided inside the cleaning cone 3, connecting the water inlet pipe and the spray nozzle 8. An annular permanent magnet 10 is provided on the outer side of the washing tub 1, located outside the inclined section. An electromagnet is installed inside the annular permanent magnet 10, which is electrically controlled. The electromagnet is a mature existing technology and will not be described in detail.
[0019] Reference Appendix Figure 1-2The side of the cleaning cone 3 is also provided with inclined sections and vertical sections, which are spaced apart. A gap is formed between the outer side of the cleaning cone 3 and the inner side of the washing tub 1. The gap is also divided into inclined sections and vertical sections. The gap is the washing chamber 5. The side of the washing tub 1 is connected to the feed pipe 6, which is connected to the washing chamber 5. A nozzle 8 is provided above the vertical section in the washing chamber 5. When the nozzle 8 is working, it cleans and flushes away the magnetic beads in the annular groove 7.
[0020] Reference Appendix Figure 2 An annular groove 7 is provided on the inclined steps on the inner side of the washing tub 1, and a nozzle 8 is connected to the inclined section on the outer side of the washing cone 3. The nozzle 8 is vertically downward and located above the vertical section of the washing chamber 5.
[0021] This invention relates to a nano-immunomagnetic bead washing device. A magnetic bead solution is introduced into the washing chamber through an inlet pipe, and the annular permanent magnet is opened. The magnetic beads in the solution are adsorbed into the annular groove. The nozzle is opened, and the water jet from the nozzle washes the magnetic beads out of the annular groove, thus completing the washing of the magnetic beads and achieving rapid washing of the magnetic beads.
[0022] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A nano-immunomagnetic bead washing device, characterized in that: The washing tub (1) is an inverted conical barrel shape. The washing tub (1) has an opening extending through it from top to bottom. The side of the washing tub (1) is provided with an inclined section and a vertical section, which are separated by the vertical section and the inclined section. A cleaning mechanism is inserted into the opening on the washing tub (1). The cleaning mechanism includes a cover plate (2) and a cleaning cone (3). The cleaning cone (3) is also an inverted conical barrel shape. The cover plate (2) is connected to the upper end face of the cleaning cone (3). The edge of the cover plate (2) is connected to the upper edge of the washing tub (1). An annular permanent magnet (10) is provided on the outer side of the washing tub (1). The annular permanent magnet (10) is located on the outside of the inclined section.
2. The nano-immunomagnetic bead washing device according to claim 1, characterized in that: The side of the cleaning cone (3) is also provided with inclined sections and vertical sections, which are spaced apart. A gap is formed between the outer side of the cleaning cone (3) and the inner side of the washing tub (1). The gap is also divided into inclined sections and vertical sections. The gap is the washing chamber (5). A feed pipe (6) is connected to the side of the washing tub (1). The feed pipe (6) is connected to the washing chamber (5).
3. The nano-immunomagnetic bead washing device according to claim 2, characterized in that: An annular groove (7) is provided on the inclined step on the inner side of the washing tub (1), and a nozzle (8) is connected to the inclined section on the outer side of the washing cone (3). The nozzle (8) is vertically downward and located above the vertical section of the washing chamber (5).
4. The nano-immunomagnetic bead washing device according to claim 3, characterized in that: The upper end of the cover plate (2) is connected to a water inlet pipe (9), and the cleaning cone (3) is provided with a connecting water pipe, which connects the water inlet pipe and the nozzle (8).