Plasma supernatant transfer system

CN224871411UActive Publication Date: 2026-10-20GUIZHOU TAIBANG BIOLOGICAL PROD
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Patent Information

Application Number
CN202522522873.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-11-27
Publication Date
2026-10-20
Estimated Expiration
2035-11-27

AI Technical Summary

Technical Problem

[0003]然而,手动调节球阀开度以将隔膜泵调整至理想转速需要花费较长的时间

Benefits of technology

[0013]本实用新型的有益效果在于:通过控制器预设缓冲桶内液位的上限值和下限值,在隔膜泵将缓冲桶内血浆上清液转移至目标罐的过程中,通过液位检测组件实时检测缓冲桶内血浆上清液的液位,并将相关信息传输给控制器,当缓冲桶内的血浆上清液液位上升至预设液位上限值时,控制器控制压力流量调节组件进行气体压力和流量调节,以增大隔膜泵的进气压力和流量,提高隔膜泵的转速,防止血浆上清液从缓冲桶内溢出,保证了产品收率;当缓冲桶内的血浆上清液液位下降至预设液位下限值时,控制器控制压力流量调节组件进行气体压力和流量调节,以减小隔膜泵的进气压力和流量,降低隔膜泵的转速,避免将缓冲桶内的血浆上清液泵空,进而避免空气经隔膜泵的进液口进入隔膜泵,从而避免目标罐内出现大量泡沫给后工序反应带来不良影响。本实用新型提供的系统可以根据缓冲桶内血浆上清液的液位高低,自动调节隔膜泵的转速,隔膜泵转速调节省时省力,且无需人员现场值守。

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Abstract

The utility model discloses a plasma supernatant transfer system belongs to blood product production auxiliary equipment technical field. The system includes buffer bucket, diaphragm pump, target jar and controller, be equipped with liquid level detection subassembly on the buffer bucket, the liquid inlet of diaphragm pump is passed through pipeline A with the bottom intercommunication of buffer bucket, the liquid outlet of diaphragm pump is passed through pipeline B and is connected with target jar, the air inlet of diaphragm pump is connected with the air inlet pipe, install electric valve and pressure flow adjusting assembly on the air inlet pipe, and pressure flow adjusting assembly is located between electric valve and diaphragm pump, the controller is electrically connected with liquid level detection subassembly, electric valve, pressure flow adjusting assembly. Realized diaphragm pump speed automatic regulation, can prevent plasma supernatant from spilling over from buffer bucket, guarantees the product yield, and can avoid diaphragm pump pumps empty plasma supernatant in buffer bucket, and then avoids the emergence of a large amount of foam in target jar to bring adverse effect to the reaction of later procedure.
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Description

Technical Field

[0001] This utility model relates to a plasma supernatant transfer system, belonging to the technical field of auxiliary equipment for blood product manufacturing. Background Technology

[0002] Currently, in the blood product production process, the workshop uses four centrifuges to separate and extract cryoprecipitate from the melted plasma. After the precipitate is separated from the plasma supernatant, the plasma supernatant discharged from the centrifuge is collected through a floor-standing buffer tank. Then, the plasma supernatant in the buffer tank is transferred to the target tank for subsequent reaction through a diaphragm pump. During this process, a ball valve is used to control the pressure and flow rate of the compressed air entering the diaphragm pump.

[0003] However, manually adjusting the ball valve opening to bring the diaphragm pump to the ideal speed takes a considerable amount of time. Furthermore, when the total outflow from the four centrifuges exceeds the outflow from the buffer tank, the fixed diaphragm pump speed causes the collected plasma supernatant in the buffer tank to accumulate, eventually overflowing and reducing product yield. Conversely, when the total outflow from the four centrifuges is less than the outflow from the buffer tank, the fixed diaphragm pump speed leads to a decrease in collected plasma supernatant in the buffer tank, eventually causing air to enter the pump and resulting in excessive foaming in the target tank, negatively impacting subsequent reactions. Therefore, during plasma supernatant transfer, on-site personnel are required to monitor the process and adjust the diaphragm pump speed in real-time using the ball valve based on the amount of plasma supernatant in the buffer tank. Utility Model Content

[0004] To solve the above-mentioned technical problems, this utility model provides a plasma supernatant transfer system.

[0005] This utility model is achieved through the following technical solution: A plasma supernatant transfer system includes a buffer tank, a diaphragm pump, a target tank, and a controller. The buffer tank is equipped with a level detection component. The inlet of the diaphragm pump is connected to the bottom of the buffer tank via pipe A, and the outlet of the diaphragm pump is connected to the target tank via pipe B. An air inlet pipe is connected to the air inlet of the diaphragm pump, and an electric valve and a pressure-flow regulating component are installed on the air inlet pipe, with the pressure-flow regulating component located between the electric valve and the diaphragm pump. The controller is electrically connected to the level detection component, the electric valve, and the pressure-flow regulating component.

[0006] The liquid level detection component is a radar liquid level gauge, which is located on top of the buffer tank.

[0007] A valve is installed on pipe A.

[0008] The valve is a diaphragm valve.

[0009] The outlet of the diaphragm pump is connected to the upper part of the target tank via pipe B.

[0010] The electric valve is an electric ball valve.

[0011] The pressure and flow regulating component is a PID pneumatic regulating valve.

[0012] It also includes a touchscreen, which is electrically connected to the controller.

[0013] The beneficial effects of this invention are as follows: By presetting the upper and lower limits of the liquid level in the buffer tank by the controller, during the process of the diaphragm pump transferring the plasma supernatant in the buffer tank to the target tank, the liquid level detection component detects the liquid level of the plasma supernatant in the buffer tank in real time and transmits the relevant information to the controller. When the liquid level of the plasma supernatant in the buffer tank rises to the preset upper limit, the controller controls the pressure and flow regulation component to regulate the gas pressure and flow, thereby increasing the inlet pressure and flow of the diaphragm pump and increasing the speed of the diaphragm pump to prevent the plasma supernatant from overflowing from the buffer tank, thus ensuring the product yield. When the liquid level of the plasma supernatant in the buffer tank drops to the preset lower limit, the controller controls the pressure and flow regulation component to regulate the gas pressure and flow, thereby reducing the inlet pressure and flow of the diaphragm pump and reducing the speed of the diaphragm pump to avoid pumping the plasma supernatant in the buffer tank empty, and thus preventing air from entering the diaphragm pump through the liquid inlet, thereby avoiding the formation of a large amount of foam in the target tank, which would have an adverse effect on subsequent reactions. The system provided by this invention can automatically adjust the speed of the diaphragm pump according to the level of the plasma supernatant in the buffer tank. The speed adjustment of the diaphragm pump is time-saving and labor-saving, and no personnel are required to be on-site. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the structure of this utility model.

[0015] In the diagram: 1-Buffer tank, 2-Valve, 3-Pipe A, 4-Diaphragm pump, 5-Pipe B, 6-Target tank, 7-Inlet pipe, 8-Electric valve, 9-Regulating component, 10-Level detection component. Detailed Implementation

[0016] The technical solution of this utility model is further described below, but the scope of protection is not limited to what is described.

[0017] like Figure 1As shown, the plasma supernatant transfer system of this utility model includes a buffer tank 1, a diaphragm pump 4, a target tank 6, and a controller. The buffer tank 1 is equipped with a liquid level detection component 10. The inlet of the diaphragm pump 4 is connected to the bottom of the buffer tank 1 through a pipe A3, and the outlet of the diaphragm pump 4 is connected to the target tank 6 through a pipe B5. An air inlet pipe 7 is connected to the air inlet of the diaphragm pump 4. An electric valve 8 and a pressure and flow regulating component 9 are installed on the air inlet pipe 7, and the pressure and flow regulating component 9 is located between the electric valve 8 and the diaphragm pump 4. The controller is electrically connected to the liquid level detection component 10, the electric valve 8, and the pressure and flow regulating component 9.

[0018] Specifically, the controller presets the upper and lower limits of the liquid level in buffer tank 1. During the process of diaphragm pump 4 transferring plasma supernatant from buffer tank 1 to target tank 6, the liquid level detection component 10 monitors the liquid level of plasma supernatant in buffer tank 1 in real time and transmits the relevant information to the controller. When the liquid level of plasma supernatant in buffer tank 1 rises to the preset upper limit, the controller controls the pressure and flow regulation component 9 to regulate the gas pressure and flow rate, thereby increasing the inlet pressure and flow rate of diaphragm pump 4 and increasing the speed of diaphragm pump 4 to prevent plasma supernatant from overflowing from buffer tank 1 and ensuring product yield. When the liquid level of plasma supernatant in buffer tank 1 drops to the preset lower limit, the controller controls the pressure and flow regulation component 9 to regulate the gas pressure and flow rate, thereby reducing the inlet pressure and flow rate of diaphragm pump 4 and reducing the speed of diaphragm pump 4 to avoid pumping the plasma supernatant in buffer tank 1 empty. This also prevents air from entering diaphragm pump 4 through the liquid inlet, thus avoiding the formation of a large amount of foam in target tank 6, which could adversely affect subsequent reactions. The system provided by this invention can automatically adjust the speed of the diaphragm pump 4 according to the level of the plasma supernatant in the buffer tank 1. The speed adjustment of the diaphragm pump 4 is time-saving and labor-saving, and no personnel are required to be on-site.

[0019] The liquid level detection component 10 is a radar liquid level gauge, which is located on the top of the buffer tank 1.

[0020] Valve 2 is installed on the pipeline A3.

[0021] Valve 2 is a diaphragm valve. The diaphragm valve is used to control the opening and closing of pipeline A3, making it easy to close pipeline A3 before disassembling the diaphragm pump 4.

[0022] The outlet of the diaphragm pump 4 is connected to the upper part of the target tank 6 through pipe B5.

[0023] The electric valve 8 is an electric ball valve. The electric ball valve is used to control the opening and closing of the air intake pipe 7.

[0024] The pressure and flow regulating component 9 is a PID pneumatic regulating valve. The PID pneumatic regulating valve regulates the inlet pressure and flow rate of the diaphragm pump 4.

[0025] It also includes a touchscreen, which is electrically connected to the controller.

Claims

1. A plasma supernatant transfer system, characterized in that: The system includes a buffer tank (1), a diaphragm pump (4), a target tank (6), and a controller. The buffer tank (1) is equipped with a liquid level detection component (10). The inlet of the diaphragm pump (4) is connected to the bottom of the buffer tank (1) through a pipe A (3). The outlet of the diaphragm pump (4) is connected to the target tank (6) through a pipe B (5). An air inlet pipe (7) is connected to the air inlet of the diaphragm pump (4). An electric valve (8) and a pressure and flow regulating component (9) are installed on the air inlet pipe (7). The pressure and flow regulating component (9) is located between the electric valve (8) and the diaphragm pump (4). The controller is electrically connected to the liquid level detection component (10), the electric valve (8), and the pressure and flow regulating component (9).

2. The plasma supernatant transfer system as described in claim 1, characterized in that: The liquid level detection component (10) is a radar liquid level gauge, which is located on top of the buffer tank (1).

3. The plasma supernatant transfer system as described in claim 1, characterized in that: A valve (2) is installed on the pipe A (3).

4. The plasma supernatant transfer system as described in claim 3, characterized in that: The valve (2) is a diaphragm valve.

5. The plasma supernatant transfer system as described in claim 1, characterized in that: The outlet of the diaphragm pump (4) is connected to the upper part of the target tank (6) through pipe B (5).

6. The plasma supernatant transfer system as described in claim 1, characterized in that: The electric valve (8) is an electric ball valve.

7. The plasma supernatant transfer system as described in claim 1, characterized in that: The pressure and flow regulating component (9) is a PID pneumatic regulating valve.

8. The plasma supernatant transfer system as described in claim 1, characterized in that: It also includes a touchscreen, which is electrically connected to the controller.