A multi-treatment room apparatus for boron neutron capture therapy

Abstract

The utility model discloses a boron neutron capture therapy is with many treatment room device, including the horizontal treatment room of same layer arrangement, vertical treatment room and the high energy transmission beam line of high energy proton beam for horizontal treatment room and vertical treatment room, high energy transmission beam line be provided with several sections, wherein, the high energy transmission beam line section of horizontal treatment room and the high energy transmission beam line section of vertical treatment room are spatially different surface arrangement. Many treatment room structure same layer arrangement, realized more pose's position irradiation requirement, can satisfy the requirement of patient arbitrary point incident point irradiation, and, high energy transmission beam line is spatially different surface arrangement, greatly saved the space, can be according to the different structure treatment room of suitable place same layer arrangement, can greatly reduce the cost of civil engineering, relative to the existing stratified setting, horizontal treatment room and vertical room same layer design, do not need to excavate basement, save stratified shielding wall body use.

Description

Technical Field

[0001] This utility model relates to the field of boron neutron capture therapy (BNCT) technology, and in particular to a multi-treatment chamber device for boron neutron capture therapy. Background Technology

[0002] Currently, boron neutron capture therapy is being increasingly adopted. To achieve irradiation at different positions, the design of treatment rooms has evolved from single treatment rooms to dual treatment rooms, and even multiple treatment rooms. However, due to limitations imposed by the beam direction, current treatment rooms are almost exclusively dual-treatment-room designs. For example, Chinese patent document CN120478854A discloses a dual-treatment-room boron neutron therapy center and its application method, and CN222871183U discloses a boron neutron capture therapy device based on a compact high-current proton RFQ accelerator. Dual treatment rooms can only accommodate irradiation in two different positions.

[0003] In addition, current multi-treatment rooms are generally arranged in layers, which requires the excavation of basements and the installation of layered shielding walls, resulting in complex structures and high costs.

[0004] To meet the requirements of more patient positioning and irradiation, it is necessary to design a multi-treatment room structure to achieve horizontal and vertical irradiation requirements for various positioning positions such as lying down and sitting, thereby enabling irradiation at any point of incidence on the patient and expanding the application range of the boron neutron capture therapy (BNCT) system. Utility Model Content

[0005] The purpose of this invention is to address the problems of existing multi-treatment room layouts, which require the excavation of basements and the installation of layered shielding walls, resulting in complex structures and high costs, and are unable to meet the design requirements of multi-treatment rooms. This invention provides a multi-treatment room device for boron neutron capture therapy, which adopts a same-layer layout. Multiple treatment rooms with different irradiation structures can be set up on the same layer according to actual needs, thereby achieving horizontal and vertical irradiation requirements for various positioning postures such as lying and sitting. The multiple treatment rooms provide high-energy proton beams through high-energy transmission beamlines arranged in a spatially dissimilar manner, thus realizing a same-layer layout and solving the problem of being unable to achieve a same-layer layout of multiple treatment rooms due to the limitation of neutron beam direction.

[0006] The technical solution adopted by this utility model to achieve its inventive purpose is: a multi-treatment-chamber device for boron neutron capture therapy, comprising a horizontal treatment chamber and a vertical treatment chamber arranged on the same floor, and a high-energy transmission beamline providing high-energy proton beams to the horizontal and vertical treatment chambers. The high-energy transmission beamline is provided with several segments, wherein the high-energy transmission beamline segment leading to the horizontal treatment chamber and the high-energy transmission beamline segment leading to the vertical treatment chamber are arranged in a spatially eccentric manner. This multi-treatment-chamber device for boron neutron capture therapy, by arranging the high-energy transmission beamline in a spatially eccentric manner, achieves the same-floor arrangement of multiple treatment chambers, meeting the requirements for different irradiation positions. It can achieve horizontal and vertical irradiation in various positions such as supine and sitting postures. Moreover, the spatially eccentric arrangement of the high-energy transmission beamline facilitates the same-floor arrangement of multiple treatment chambers, greatly saving space. Different structural arrangements can be made according to the applicable location, resulting in a small footprint. By arranging horizontal and vertical treatment rooms on the same floor, construction costs can be significantly reduced. Compared to the existing multi-level layout, there is no need to excavate a basement, saving on the use of partition walls. It also facilitates the design of unified patient and staff flow routes, allowing for a more compact arrangement of treatment rooms, observation rooms, and emergency rooms.

[0007] Preferably, the beam exit direction of the horizontal treatment room is arranged on the same horizontal plane and perpendicular to the central axis of the high-energy transmission beam outlet; the beam exit direction of the vertical treatment room is arranged on the same vertical plane and perpendicular to the central axis of the high-energy transmission beam outlet. The treatment bed in the horizontal treatment room needs to be able to rotate 180° around the beam center to meet the patient's coronal circumferential irradiation angle requirements as much as possible. Therefore, the effective usable space of the horizontal treatment room is a narrow rectangle perpendicular to the beam direction. The beam exit direction of the horizontal treatment room is perpendicular to the central axis of the high-energy transmission beam, which ensures that the long axis of the horizontal treatment room on both sides of the high-energy transmission beam's central axis is consistent with the direction of the high-energy transmission beam's central axis, minimizing the layout size perpendicular to the high-energy transmission beam's central axis. This allows adjacent treatment rooms or positioning rooms to share shielding walls without forming abnormal angles between the shielding walls, thus avoiding wasted space and increased shielding wall requirements. The beam exit direction of the vertical treatment chamber is set to achieve irradiation of the patient's head, neck and face. Therefore, the beam exit direction of the vertical treatment chamber and the central axis of the high-energy transmission beam outlet are arranged on the same vertical plane and are perpendicular to each other.

[0008] Preferably, the horizontal treatment chamber includes a first horizontal treatment chamber located on the first side of the central axis where the high-energy transmission beam exit is located and / or a second horizontal treatment chamber located on the second side of the central axis where the high-energy transmission beam exit is located. Alternatively, the horizontal treatment chambers can be arbitrarily arranged on either side of the high-energy transmission beam as needed.

[0009] Preferably, the first and second level treatment rooms are each equipped with a treatment bed and a treatment chair; the first and second level treatment rooms are each equipped with a treatment chair and a treatment bed. A treatment bed can be installed in the first level treatment room to achieve circumferential irradiation of the patient's head and neck in the coronal plane. A treatment chair can also be installed in the first level treatment room to achieve translation in the up, down, left, and right directions, thereby achieving irradiation of the patient's head and neck in the back direction. Similarly, a treatment bed or treatment chair can also be optionally installed in the second treatment room.

[0010] Preferably, an accelerator hall and a high-energy beamline delivery hall are also included. To provide high-energy proton beams to each treatment room, an accelerator hall and a high-energy beamline delivery hall for implementing the high-energy beamline setup are also provided.

[0011] Preferably, an ion source and an accelerator are installed inside the accelerator hall, and the accelerator and the ion source are connected by a low-energy transmission beam; the high-energy transmission beam is connected to the accelerator.

[0012] Another technical solution adopted by this utility model to achieve its invention objective is: a multi-treatment chamber device for boron neutron capture therapy, comprising a first horizontal treatment chamber, a second horizontal treatment chamber, and a vertical treatment chamber arranged on the same floor. Each of the first and second horizontal treatment chambers is provided with a treatment bed or a treatment chair. A treatment bed or treatment chair is provided inside the vertical treatment chamber. The device also includes high-energy transmission beamlines that provide high-energy proton beams to the three treatment chambers. The high-energy transmission beamline segments leading to the first / second horizontal treatment chambers and the high-energy transmission beamline segments leading to the vertical treatment chamber are arranged in a spatially eccentric manner. This multi-treatment-room device can be used in conjunction with treatment beds or chairs to meet the requirements of different patient positions. By spatially arranging the high-energy transmission beams in a non-planar manner, multiple treatment rooms can be arranged on the same floor, satisfying the requirements for irradiation selection in different positions. It can achieve horizontal and vertical irradiation in various positions such as lying and sitting. Moreover, the spatially non-planar arrangement of the high-energy transmission beams facilitates the co-floor arrangement of multiple treatment rooms. The co-floor arrangement of horizontal and vertical treatment rooms can significantly reduce civil engineering costs. Compared with the existing layered arrangement, there is no need to excavate a basement, saving the use of layered shielding walls. At the same time, it is easier to design a unified flow route for patients and operators, and the treatment rooms, observation rooms, and emergency rooms can be more compact. The first and second horizontal treatment rooms and the vertical treatment room form a three-room co-floor arrangement structure, which is the optimal solution for beam utilization efficiency. The usage time mainly includes half an hour of positioning time, 30-40 minutes of treatment time, and half an hour of release time. Within a reasonable time frame, the maximum utilization rate of the treatment rooms can be achieved. By spatially arranging the high-energy transmission beamlines in different planes, multiple treatment rooms can be arranged on the same floor, which can meet the requirements of different positioning postures for irradiation. It can achieve horizontal and vertical irradiation in various positioning postures such as lying and sitting. Moreover, the spatially arranging high-energy transmission beamlines in different planes facilitates the same-floor arrangement of multiple treatment rooms, greatly saves space, and can be arranged in different structures according to the applicable location, with a small footprint.

[0013] Preferably, the beam exit directions of the first and second level treatment rooms are arranged in a Y-shape or T-shape with the central axis of the high-energy transmission beam on the same horizontal plane. This arrangement allows adjacent treatment rooms or placement rooms to share a common shielding wall, preventing the formation of irregular angles between the shielding walls and avoiding wasted space and additional shielding walls.

[0014] Preferably, the beam exit direction of the vertical treatment chamber is perpendicular to the central axis of the high-energy transmission beam, but not aligned with it. This facilitates the simultaneous layout of multiple treatment chambers on the same floor.

[0015] Preferably, the first horizontal treatment room, the second horizontal treatment room, and the vertical treatment room are arranged in a U-shaped structure.

[0016] Preferably, the first horizontal treatment room, the second horizontal treatment room, and the vertical treatment room each include a treatment area and a positioning area, and a labyrinth is provided outside the positioning area of ​​the first horizontal treatment room and the second horizontal treatment room.

[0017] Preferably, the treatment bed includes a multi-degree-of-freedom robotic arm and a treatment bed board, and the treatment chair includes a multi-degree-of-freedom robotic arm and a treatment chair body.

[0018] Preferably, it also includes an accelerator hall and a high-energy beamline delivery hall.

[0019] Preferably, an ion source and an accelerator are installed inside the accelerator hall, and the accelerator and the ion source are connected by a low-energy transmission beam; the high-energy transmission beam is connected to the accelerator.

[0020] The beneficial effects of this utility model are: (1) The multi-treatment room device for boron neutron capture therapy has multiple treatment room structures arranged on the same floor, realizing more positioning and irradiation requirements, and meeting the requirements for irradiation of any point of incidence on the patient. Moreover, the high-energy transmission beam is arranged in a spatially non-planar manner, which greatly saves space. Different treatment rooms can be arranged on the same floor according to the applicable location, which can greatly reduce the civil engineering cost. Compared with the existing layered setting, the horizontal treatment room and the vertical room are designed on the same floor, which does not require the excavation of a basement and saves the use of layered shielding walls. At the same time, it is convenient to design a unified flow route for patients and operators, and the treatment room, observation room and emergency room can be more compact.

[0021] (2) The beam output direction of the horizontal treatment room is perpendicular to the central axis of the high-energy transmission beam outlet, which optimizes the spatial layout of the treatment room. It can make the long axis of the horizontal treatment room on both sides of the central axis of the high-energy transmission beam outlet consistent with the direction of the central axis of the high-energy transmission beam outlet, minimizing the layout size perpendicular to the central axis of the high-energy transmission beam outlet. It can meet the requirement of sharing shielding walls between adjacent treatment rooms or positioning rooms, and there is no abnormal angle between the shielding walls, which would cause space waste and increase the number of shielding walls. The horizontal treatment room can be made into a square structure relative to the entire device layout area, which makes it less likely for the robotic arm to collide when moving the treatment bed / treatment chair, and at the same time greatly improves the space utilization rate.

[0022] (3) The layout of three treatment rooms for all-round treatment on the same floor, and the structure of treatment chair in the horizontal treatment room, treatment bed in the horizontal treatment room, and treatment bed / treatment chair in the vertical treatment room, allows for the selection of suitable treatment rooms for different patients on the same floor. For any head and neck lesion irradiation needs in the patient group, the best treatment placement scheme with the best patient experience can be selected from the treatment room schemes such as treatment chair in the horizontal treatment room, treatment bed in the horizontal treatment room, and treatment bed / treatment chair in the vertical treatment room. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of a multi-treatment chamber device for boron neutron capture therapy in Example 1.

[0024] Figure 2 This is another structural schematic diagram of the multi-treatment chamber device for boron neutron capture therapy in Example 1.

[0025] Figure 3 This is a schematic diagram of a high-energy transmission beam in Example 1.

[0026] Figure 4 This is a structural diagram of another embodiment of the multi-treatment chamber device for boron neutron capture therapy in Example 1.

[0027] Figure 5 This is a schematic diagram of a multi-treatment chamber device for boron neutron capture therapy in Example 2.

[0028] Figure 6 This is another structural schematic diagram of the multi-treatment chamber device for boron neutron capture therapy in Example 2.

[0029] Figure 7 This is a schematic diagram of a high-energy transmission beam in Example 2.

[0030] Figure 8 This is a structural diagram of another embodiment of the multi-treatment chamber device for boron neutron capture therapy in Example 2.

[0031] Figure 9 This is a schematic diagram of a multi-treatment chamber device for boron neutron capture therapy in Example 3.

[0032] Figure 10 This is another structural schematic diagram of the multi-treatment chamber device for boron neutron capture therapy in Example 3.

[0033] Figure 11 This is a schematic diagram of a high-energy transmission beam in Example 3.

[0034] Figure 12 This is a structural diagram of another embodiment of the multi-treatment chamber device for boron neutron capture therapy in Example 3.

[0035] In the image: 1. Accelerator lobby; 2. Vertical treatment room; 3. Horizontal treatment room; 31. First-level treatment room; 32. Second-level treatment room; 4. High-energy transmission cable; 41. High-energy transmission cable output section; 42. High-energy transmission beam horizontal section; 421. Horizontal vertical entry section; 422. Same-layer horizontal transmission section. 43. High-energy transmission beam spatial segment; 431. Spatial upward vertical segment; 432. Spatial horizontal segment; 433. Spatial downward vertical entry segment. 5. Neutron beam shaping body; 51. Horizontal neutron beam shaping body; 52. Vertical neutron beam shaping body. 6. Ion source, 7. Accelerator, 8. Low-energy transmission harness 9. Positioning room; 91. Horizontal recumbent positioning room; 92. Vertical recumbent positioning room; 93. Horizontal sitting positioning room; 94. Labyrinth. 10. Neutron shielding gate; 11. Proton beam focusing or diffusing magnet; 12. Directional magnet. 13. Treatment bed; 131. Treatment bed board; 14. Treatment chair; 141. Main body of the treatment chair; 15. Multi-degree-of-freedom robotic arm; 20. High-energy beam delivery hall; 30. Radiation protection shielding door. Detailed Implementation

[0036] The present invention will now be described in detail with reference to specific embodiments and accompanying drawings.

[0037] Example 1: exist Figure 1 , Figure 3 , Figure 4 In the illustrated embodiment, a multi-treatment-chamber device for boron neutron capture therapy includes a horizontal treatment chamber 3 and a vertical treatment chamber 2 arranged on the same floor, and a high-energy transmission beamline 4 providing high-energy proton beams to the horizontal treatment chamber 3 and the vertical treatment chamber 2. The high-energy transmission beamline 4 has several segments, wherein the high-energy transmission beamline segments leading to the horizontal treatment chamber and the high-energy transmission beamline segments leading to the vertical treatment chamber are arranged spatially out of plane. It also includes an accelerator hall 1 and a high-energy beamline delivery hall 20. The multiple treatment chambers have different irradiation postures.

[0038] An ion source 6 and an accelerator 7 are installed inside the accelerator hall 1. In this embodiment, the accelerator 7 is a radio frequency linear accelerator, and the accelerator 7 is connected to the ion source 6 via a low-energy transmission cable 8. In this embodiment, the multi-treatment chamber device for boron neutron capture therapy has an overall L-shaped structure (see...). Figure 1 ) or in a rectangular structure (see Figure 2 Integrated settings.

[0039] High-energy proton beams are provided to multiple treatment rooms with different irradiation structures through a spatially eccentrically arranged high-energy transmission beamline 4. The neutron beams generated by multiple treatment rooms can irradiate any incident point on the head and neck of the patient, achieving full coverage of the head and neck in a relatively comfortable posture. High-energy transmission beamline 4 transmits the high-energy proton beams generated by the radiofrequency linear accelerator to different treatment rooms through a vacuum cavity.

[0040] In this embodiment, there are a first horizontal treatment chamber 31 and a vertical treatment chamber 2 located on the first side of the high-energy transmission beam 4, which are arranged on the same floor. The first horizontal treatment chamber 31 and the vertical treatment chamber 2 are arranged on the same floor in an L-shaped structure.

[0041] The treatment chamber is equipped with a neutron beam shaping device 5. The neutron beam shaping device 5 includes a horizontal neutron beam shaping device 51 located in the horizontal treatment chamber and a vertical neutron beam shaping device 52 located in the vertical treatment chamber.

[0042] A horizontal neutron beam shaper 51 is provided inside the first horizontal treatment chamber 31, and a vertical neutron beam shaper 52 is provided inside the vertical treatment chamber.

[0043] The beam exit direction A of the horizontal treatment chamber 3 is arranged on the same horizontal plane and perpendicular to each other with the central axis L where the high-energy transmission beam outlet is located; the beam exit direction B of the vertical treatment chamber 2 is arranged on the same vertical plane and perpendicular to each other with the central axis L where the high-energy transmission beam outlet is located. The horizontal treatment chamber 3 includes a first horizontal treatment chamber 31 located on the first side of the high-energy transmission beam 4.

[0044] Furthermore, to facilitate positioning, both the first horizontal treatment room 31 and the vertical treatment room 2 include a treatment area and a positioning area, with the positioning area equipped with a positioning room 9.

[0045] The first horizontal treatment room 31 includes a treatment area and a positioning area. The treatment area includes a horizontal supine treatment room, and the positioning area includes a horizontal supine positioning room 91. The horizontal supine positioning room 91 has a labyrinth structure inside. A neutron shielding door 10 and a radiation protection shielding door 30 are provided between the horizontal supine positioning room 91 and the horizontal supine treatment room. The vertical treatment room 2 is divided into a treatment area and a positioning area. The treatment area includes a vertical supine treatment room, and the positioning area includes a vertical supine positioning room 92. The vertical supine positioning room 92 does not have a labyrinth inside.

[0046] The accelerator hall 1 and the high-energy beamline delivery hall 20 are arranged on the same floor and adjacent to each other. A neutron shielding door 10 is also provided between the accelerator hall 1 and the high-energy beamline delivery hall 20.

[0047] The ion source 6 utilizes the resonance of microwaves and electrons' cyclotron motion in a magnetic field to generate a high-density plasma proton source, exhibiting characteristics of high flux, high stability, and low emittance. The low-energy transmission beam 8 contains a vacuum cavity that guides the proton beam generated by the ion source into the radio frequency linear accelerator and homogenizes the proton beam. The radio frequency linear accelerator accelerates the proton beam over a short distance, outputting a high-energy, high-flux proton beam.

[0048] The high-energy transmission beamline 4 is located inside the high-energy beamline delivery hall 20 and passes through the hall to connect with the radio frequency linear accelerator. The high-energy transmission beamline 4 is configured to transmit the high-energy proton beam generated by the radio frequency linear accelerator to different treatment rooms via a vacuum chamber.

[0049] Several proton beam focusing or diffusing magnets 11 and deflecting magnets 12 are provided on the high-energy transmission beamline 4. The high-energy transmission beamline 4 is deflected by the deflecting magnets 12 to achieve spatially skewed arrangement. The proton beam focusing or diffusing magnets 11 can be, for example, quadrupole magnets, which generate magnetic fields with four alternating polarities by energizing the coil windings, focusing or diffusing the proton beam in the high-energy transmission beamline to obtain a proton beam that meets the requirements for bombarding the proton target. The deflecting magnets 12 can be, for example, dipole magnets, which generate magnetic fields with two polarities by energizing the coil windings, driving the proton beam in the high-energy transmission beamline to deflect.

[0050] In this embodiment, the high-energy transmission beam 4 is provided with several segments, mainly including a high-energy transmission beam output segment 41, a high-energy transmission beam horizontal plane segment 42, and a high-energy transmission beam spatial segment 43.

[0051] The high-energy transmission beamline output section 41 is connected to the radio frequency linear accelerator and is located inside the accelerator hall 1. The beam outlet of the radio frequency linear accelerator is the outlet of the high-energy transmission beamline 4. The central axis L of the outlet of the high-energy transmission beamline 4 is coaxial with the high-energy transmission beamline output section 4. The horizontal section 42 of the high-energy transmission beamline passes through the high-energy beamline delivery hall 20 and connects to the high-energy transmission beamline output section 41.

[0052] The high-energy transmission beam horizontal section 42 includes a same-level horizontal transmission section 422 and a horizontal-vertical entry section 421 leading to the horizontal treatment room. The same-level horizontal transmission section 422 is deflected 90 degrees in the high-energy beam delivery hall 20 by a deflecting magnet 12, forming a horizontal-vertical entry section 421 leading to the first horizontal treatment room 31. The horizontal-vertical entry section 421 can be deflected 90 degrees to the left or to the right (see figure). The horizontal-vertical entry section 421 is the high-energy transmission beam leading to the horizontal treatment room.

[0053] The high-energy transmission beamline spatial segment 43 includes a spatial upward vertical segment 431 and a spatial horizontal segment 432. The high-energy transmission beamline is first deflected in the output segment 41 and set vertically upward to form the spatial upward vertical segment 431. Then, after a second deflection, it is set horizontally in the air above the high-energy beamline delivery hall and enters the vertical treatment room to form the spatial horizontal segment 432. Finally, it undergoes a third deflection in the vertical treatment room to achieve a vertical downward setting of the high-energy transmission beamline from top to bottom, forming the spatial downward vertical entry segment 433, thereby enabling the bombardment of the neutron target inside the vertically set neutron beam shaping body.

[0054] like Figure 4 As shown, in another embodiment, to meet the requirement of adjusting the irradiation positioning at the patient's incident angle, a treatment bed 13 is provided inside the first water therapy chamber 31. A treatment bed 13 or a treatment chair 14 is provided inside the vertical treatment chamber 2. The treatment bed 13 includes a multi-degree-of-freedom robotic arm 15 and a treatment bed board 131, and the treatment chair 14 includes a multi-degree-of-freedom robotic arm 15 and a treatment chair body 141. The treatment bed board is made of carbon fiber material.

[0055] The multi-degree-of-freedom robotic arm and treatment bed facilitate patients' horizontal and vertical positioning for irradiation.

[0056] In the first-level treatment room, a positioning membrane is used to fix the patient to the treatment bed board. The treatment bed board, supported by a multi-degree-of-freedom robotic arm, can rotate 180°, thereby enabling circumferential irradiation of the patient's head and neck in the coronal plane.

[0057] In the vertical treatment room, a positioning membrane is used to fix the patient to the treatment bed. The treatment chair, supported by a multi-degree-of-freedom robotic arm, can move forward, backward, left, and right to achieve irradiation of the patient's head, neck, and face.

[0058] Example 2: exist Figure 5 , Figure 6 , Figure 7 , Figure 8In the illustrated embodiment, a multi-treatment-chamber device for boron neutron capture therapy includes a horizontal treatment chamber 3 and a vertical treatment chamber 2 arranged on the same floor, and a high-energy transmission beamline 4 providing high-energy proton beams to the horizontal treatment chamber 3 and the vertical treatment chamber 2. The high-energy transmission beamline 4 has several segments, wherein the high-energy transmission beamline segments leading to the horizontal treatment chamber and the high-energy transmission beamline segments leading to the vertical treatment chamber are arranged spatially out of plane. It also includes an accelerator hall 1 and a high-energy beamline delivery hall 20. The multiple treatment chambers have different irradiation postures.

[0059] This multi-chamber device for boron neutron capture therapy has an overall L-shaped structure (see...). Figure 5 ) or in a rectangular structure (see Figure 6 Integrated setup. Its technical solution is basically the same as that of Embodiment 1, except that: The multi-chamber device for boron neutron capture therapy includes a second horizontal treatment chamber 32 and a vertical treatment chamber 2 located on the second side of the high-energy transmission beamline 4. The second horizontal treatment chamber 32 and the vertical treatment chamber 2 are arranged in an L-shape on the same floor. A horizontal neutron beam shaper 51 is installed inside the second horizontal treatment chamber 32, and a vertical neutron beam shaper 52 is installed inside the vertical treatment chamber 2.

[0060] The beam exit direction A of the second horizontal treatment chamber 32 is arranged on the same horizontal plane and perpendicular to each other with the central axis L of the high-energy transmission beam outlet; the beam exit direction B of the vertical treatment chamber 2 is arranged on the same vertical plane and perpendicular to each other with the central axis L of the high-energy transmission beam outlet. The vertical treatment chamber 2 is coaxially or eccentrically arranged with the central axis L of the high-energy transmission beam outlet. The central axis of the high-energy transmission beam outlet is coaxial with the proton beam exit axis of the radio frequency linear accelerator.

[0061] like Figure 8 As shown, in another embodiment, for ease of positioning, the second horizontal treatment room 32 includes a treatment area and a positioning area. The treatment area is a horizontal sitting treatment room, and the positioning area is a horizontal sitting positioning room 93. A neutron shielding door 10 and a radiation protection shielding door 30 are provided between the horizontal sitting positioning room 93 and the horizontal sitting treatment room. The vertical treatment room 2 includes a treatment area and a positioning area. In this embodiment, the treatment area is a vertical supine treatment room, and the positioning area includes a vertical supine positioning room 92. Since the irradiation in the vertical treatment room is perpendicular to the ground, a labyrinth structure is not required inside the vertical supine positioning room 92.

[0062] In this embodiment, the multi-degree-of-freedom robotic arm 15 and the treatment bed 131 facilitate the patient's vertical supine position for irradiation. The multi-degree-of-freedom robotic arm 15 and the treatment chair body 141 facilitate the patient's horizontal seated position for irradiation.

[0063] In the vertical treatment room, a positioning membrane is used to fix the patient to the treatment bed. The treatment chair, supported by a multi-degree-of-freedom robotic arm, can move forward, backward, left, and right to achieve irradiation of the patient's head, neck, and face.

[0064] In the second-level treatment room, a treatment chair is set up. The multi-degree-of-freedom robotic arm and the main body of the treatment chair facilitate the patient's sitting posture. The positioning membrane is used to fix the patient on the treatment chair. The treatment chair supported by the multi-degree-of-freedom robotic arm can be moved up, down, left and right, so as to achieve irradiation of the patient's head, neck and back.

[0065] Example 3: exist Figure 9 , Figure 10 , Figure 11 , Figure 12 In the embodiment shown, a multi-treatment chamber device for boron neutron capture therapy includes a first horizontal treatment chamber 31, a second horizontal treatment chamber 32, and a vertical treatment chamber 2 arranged on the same floor. A treatment bed 13 or a treatment chair 14 is respectively installed inside the first horizontal treatment chamber 31, the second horizontal treatment chamber 32, and the vertical treatment chamber 2.

[0066] It also includes a high-energy transmission beamline 4 providing high-energy proton beams to the first horizontal treatment chamber 31, the second horizontal treatment chamber 32, and the vertical treatment chamber 2. The high-energy transmission beamline 4 has several segments, with the segments leading to the first and second horizontal treatment chambers and the segment leading to the vertical treatment chamber arranged in a spatially skewed manner. The beam exit directions of the first and second horizontal treatment chambers are respectively arranged on the same horizontal plane and perpendicular to each other with the central axis of the high-energy transmission beamline exit point. The beam exit directions of the first and second horizontal treatment chambers 31 and 32 are arranged in a Y-shape or T-shape with the central axis of the high-energy transmission beamline 4 exit point. The beam exit direction of the vertical treatment chamber 2 is arranged on the same vertical plane and perpendicular to each other with the central axis of the high-energy transmission beamline exit point.

[0067] In this embodiment, the beam exit directions of the first and second horizontal treatment chambers are arranged along the same axis (e.g., T-shaped). In another embodiment, the beam exit directions of the first and second horizontal treatment chambers may be arranged along different axes (e.g., Y-shaped).

[0068] In this embodiment, the multi-treatment chamber device for boron neutron capture therapy is T-shaped overall (see...). Figure 9 ) or rectangular structure (see Figure 10 Integrated settings.

[0069] The first horizontal treatment room 31, the second horizontal treatment room 32, and the vertical treatment room 2 are arranged in a U-shape around the outside of the high-energy beam delivery hall 20.

[0070] In this embodiment, a treatment bed 13 is installed inside the first horizontal treatment room 31, a treatment chair 14 is installed inside the second horizontal treatment room 32, and a treatment bed 13 is installed inside the vertical treatment room 2. The first horizontal treatment room 31 allows for circumferential irradiation of the patient's head and neck in the coronal plane at various angles; the second horizontal treatment room 32 allows for irradiation of the back of the patient's head and neck; and the vertical treatment room 2 allows for irradiation of the face of the patient's head and neck.

[0071] In another embodiment, a treatment bed 13 is provided inside the first horizontal treatment room 31, a treatment chair 14 is provided inside the second horizontal treatment room 32, and a treatment chair 14 is provided inside the vertical treatment room 2.

[0072] In another embodiment, a treatment chair 14 is provided inside the first horizontal treatment room 31, a treatment bed 13 is provided inside the second horizontal treatment room 32, and a treatment bed 13 is provided inside the vertical treatment room 2.

[0073] In another embodiment, a treatment chair 14 is provided inside the first horizontal treatment room 31, a treatment bed 13 is provided inside the second horizontal treatment room 32, and a treatment chair 14 is provided inside the vertical treatment room 2.

[0074] Each of the three treatment rooms—the first horizontal treatment room 31, the second horizontal treatment room 32, and the vertical treatment room 2—includes a treatment area and a positioning area. A maze 94 is also provided outside the positioning areas of the first horizontal treatment room 31 and the second horizontal treatment room 32. Each of the three treatment rooms has a positioning room 9: a horizontal supine positioning room 91, a horizontal sitting positioning room 93, and a vertical supine positioning room 92. The horizontal supine positioning room 91 and the horizontal sitting positioning room 93 are designed with a maze structure; however, other radiation-proof structures can also be used. The specific design can be customized as needed without specific limitations. The vertical supine positioning room 92 may not have a maze.

[0075] In this embodiment, the high-energy transmission beam 4 is provided with several segments, mainly including a high-energy transmission beam output segment 41, a high-energy transmission beam horizontal plane segment 42, and a high-energy transmission beam spatial segment 43.

[0076] The high-energy transmission beamline output section 41 is connected to the radio frequency linear accelerator and is located inside the accelerator hall 1. The beam outlet of the radio frequency linear accelerator is the outlet of the high-energy transmission beamline 4. The central axis L of the outlet of the high-energy transmission beamline 4 is coaxial with the high-energy transmission beamline output section 4. The horizontal section 42 of the high-energy transmission beamline passes through the high-energy beamline delivery hall 20 and connects to the high-energy transmission beamline output section 41.

[0077] The high-energy beamline horizontal section 42 includes a horizontal transmission section 422 on the same level and a horizontal-vertical entry section 421 leading to the horizontal treatment chamber. The horizontal transmission section 422 on the same level is deflected 90 degrees to both sides of the high-energy beamline delivery hall 20 by a steering magnet 12, forming two horizontal-vertical entry sections 421 leading to the first horizontal treatment chamber 31 and the second horizontal treatment chamber. This allows for the bombardment of the neutron target inside the horizontally positioned neutron beam shaping body.

[0078] The high-energy transmission beamline spatial segment 43 includes a spatial upward vertical segment 431 and a spatial horizontal segment 432. The high-energy transmission beamline is first deflected in the output segment 41 and set vertically upward to form the spatial upward vertical segment 431. Then, after a second deflection, it is set horizontally in the air above the high-energy beamline delivery hall and enters the vertical treatment room to form the spatial horizontal segment 432. Finally, it undergoes a third deflection in the vertical treatment room to achieve a vertical downward setting of the high-energy transmission beamline from top to bottom, forming the spatial downward vertical entry segment 433, thereby enabling the bombardment of the neutron target inside the vertically set neutron beam shaping body.

[0079] In this embodiment, as Figure 12 As shown, in the first-level treatment room, a positioning membrane is used to fix the patient to the treatment bed board. The treatment bed board, supported by a multi-degree-of-freedom robotic arm, can rotate 180°, thereby enabling circumferential irradiation of the patient's head and neck in the coronal plane.

[0080] In the vertical treatment room, a positioning membrane is used to fix the patient to the treatment bed. The treatment chair, supported by a multi-degree-of-freedom robotic arm, can move forward, backward, left, and right to achieve irradiation of the patient's head, neck, and face.

[0081] In the second-level treatment room, the multi-degree-of-freedom robotic arm and the main body of the treatment chair facilitate the patient's sitting posture. The positioning membrane is used to fix the patient on the treatment chair. The treatment chair supported by the multi-degree-of-freedom robotic arm can be moved up, down, left and right, thereby achieving irradiation of the patient's head, neck and back.

[0082] The multi-treatment-chamber device for boron neutron capture therapy described in the above embodiments features multiple treatment chambers arranged on the same floor, enabling more flexible irradiation positions and meeting the requirement of irradiating patients at any incident point. Furthermore, the high-energy transmission beams are arranged in a spatially non-planar manner, significantly saving space. Different treatment chamber structures can be arranged on the same floor according to the applicable location, greatly reducing civil engineering costs. Compared to existing layered setups, the design of horizontal and vertical treatment chambers on the same floor eliminates the need for basement excavation, saving on the use of layered shielding walls. It also facilitates the design of unified patient and operator flow routes, allowing for a more compact arrangement of treatment rooms, observation rooms, and emergency rooms.

[0083] The beam emission direction of the horizontal treatment chamber is perpendicular to the central axis of the high-energy transmission beam outlet, optimizing the spatial layout of the treatment chamber. This allows the long axis of the horizontal treatment chambers on both sides of the central axis of the high-energy transmission beam outlet to align with the central axis, minimizing the layout dimensions perpendicular to the central axis. It also allows adjacent treatment chambers or placement rooms to share shielding walls, preventing irregular angles between shielding walls that would waste space or increase the number of shielding walls required. Furthermore, the horizontal treatment chamber can be designed as a square structure relative to the overall equipment deployment area, reducing the likelihood of collisions when the robotic arm moves the treatment bed / chair, while significantly improving space utilization.

[0084] The layout of three treatment rooms on the same floor provides comprehensive treatment. The structure includes treatment chairs in horizontal treatment rooms, treatment beds in horizontal treatment rooms, and treatment beds / chairs in vertical treatment rooms. This allows patients on the same floor to choose the appropriate treatment room for different treatment areas. For any head and neck lesion in the patient group, the treatment placement scheme with the best patient experience can be selected from the treatment room options such as treatment chairs in horizontal treatment rooms, treatment beds in horizontal treatment rooms, and treatment beds / chairs in vertical treatment rooms.

Claims

1. A multi-chamber treatment device for boron neutron capture therapy, characterized in that: It includes a horizontal treatment room (3) and a vertical treatment room (2) arranged on the same floor, and a high-energy transmission beamline (4) that provides high-energy proton beams for the horizontal treatment room and the vertical treatment room. The high-energy transmission beamline (4) is provided with several segments, wherein the high-energy transmission beamline segment leading to the horizontal treatment room and the high-energy transmission beamline segment leading to the vertical treatment room are arranged in a spatially eccentric manner.

2. The multi-chamber treatment device for boron neutron capture therapy according to claim 1, characterized in that: The beam output direction of the horizontal treatment chamber (3) is arranged on the same horizontal plane and perpendicular to each other with the central axis where the high-energy transmission beam outlet is located; the beam output direction of the vertical treatment chamber (2) is arranged on the same vertical plane and perpendicular to each other with the central axis where the high-energy transmission beam outlet is located.

3. The multi-chamber treatment device for boron neutron capture therapy according to claim 2, characterized in that: The horizontal treatment chamber (3) includes a first horizontal treatment chamber (31) located on the first side of the central axis where the high-energy transmission beam (4) exits and / or a second horizontal treatment chamber (32) located on the second side of the central axis where the high-energy transmission beam (4) exits.

4. The multi-treatment chamber device for boron neutron capture therapy according to claim 3, characterized in that: The first horizontal treatment room (31) and the second horizontal treatment room (32) are respectively equipped with a treatment bed (13) and a treatment chair (14); or, the first horizontal treatment room (31) and the second horizontal treatment room (32) are respectively equipped with a treatment chair (14) and a treatment bed (13).

5. The multi-chamber treatment device for boron neutron capture therapy according to any one of claims 1 to 4, characterized in that: It also includes an accelerator hall (1) and a high-energy beamline delivery hall (20); an ion source (6) and an accelerator (7) are provided inside the accelerator hall (1), and the accelerator (7) and the ion source (6) are connected by a low-energy transmission beamline (8); the high-energy transmission beamline (4) is connected to the accelerator (7).

6. A multi-chamber treatment device for boron neutron capture therapy, characterized in that: It includes a first horizontal treatment room (31), a second horizontal treatment room (32), and a vertical treatment room (2) arranged on the same floor; each of the first horizontal treatment room (31) and the second horizontal treatment room (32) is provided with a treatment bed or a treatment chair, and a treatment bed (13) or a treatment chair (14) is provided inside the vertical treatment room (2); it also includes a high-energy transmission beamline (4) that provides high-energy proton beams to the three treatment rooms, wherein the high-energy transmission beamline segment leading to the first / second horizontal treatment room and the high-energy transmission beamline segment leading to the vertical treatment room are arranged in a spatially eccentric manner.

7. The multi-treatment chamber device for boron neutron capture therapy according to claim 6, characterized in that: The beam exit directions of the first horizontal treatment chamber (31) and the second horizontal treatment chamber (32) are arranged in a Y-shape or T-shape on the same horizontal plane as the central axis of the high-energy transmission beam line (4) outlet.

8. The multi-treatment chamber device for boron neutron capture therapy according to claim 6, characterized in that: The first horizontal treatment room (31), the second horizontal treatment room (32) and the vertical treatment room (2) are arranged in a U-shaped structure. The first horizontal treatment room (31), the second horizontal treatment room (32) and the vertical treatment room (2) include a treatment area and a positioning area, respectively. The positioning area of ​​the first horizontal treatment room (31) and the second horizontal treatment room (32) is also provided with a labyrinth (94).

9. The multi-chamber treatment device for boron neutron capture therapy according to any one of claims 6 to 8, characterized in that: The treatment bed (13) includes a multi-degree-of-freedom robotic arm (15) and a treatment bed board (131); the treatment chair (14) includes a multi-degree-of-freedom robotic arm (15) and a treatment chair body (141).

10. The multi-chamber treatment device for boron neutron capture therapy according to any one of claims 6 to 8, characterized in that: It also includes an accelerator hall (1) and a high-energy beamline delivery hall (20); an ion source (6) and an accelerator (7) are provided inside the accelerator hall (1), and the accelerator (7) and the ion source (6) are connected by a low-energy transmission beamline (8); the high-energy transmission beamline (4) is connected to the accelerator (7).

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