Membrane solvent based extraction apparatus

Abstract

The utility model provides an extraction device based on membrane solvent, including receiving phase, sample phase and organic phase in the container, receiving phase is used for receiving the product of extraction, sample phase is used for placing the sample of extraction, organic phase is located between receiving phase and sample phase, organic phase includes two extraction membranes, is equipped with membrane solvent between two extraction membranes, the sample of sample phase enters receiving phase after extraction membrane and membrane solvent extraction and obtains the product after extraction, the utility model discloses two extraction membranes form independent organic phase area, and membrane solvent is limited between two membranes, effectively reduces diffusion loss, ensures that the mass transfer process is continuously efficient, solves the defect that traditional device membrane solvent cannot supplement, provides two kinds of container structure of separation formula and integral type, and separation formula is convenient for each component separate cleaning and replacement, and integral type is simple to operate, and the sealing property is good, can choose according to different extraction scene, and the adaptability is strong.

Description

Technical Field

[0001] This utility model relates to the field of membrane extraction technology, and specifically to an extraction device based on membrane solvent. Background Technology

[0002] Membrane extraction devices are separation equipment that combine "membrane separation" and "solvent extraction". Their core function is to achieve two-phase (liquid-liquid) contact through porous or dense membranes, and to efficiently separate the target components in the mixture, so as to facilitate the recovery of the target product or the detection of the target substance in the sample liquid. Polypropylene membranes are the most widely used in membrane extraction devices.

[0003] In conventional membrane extraction devices, the polypropylene membrane is usually pre-fixed at the bottom of the receiving chamber. After the extraction begins, the sample solution is first added to the sample chamber, then the membrane solvent is applied to the polypropylene membrane, and then the receiving chamber with the membrane solvent at one end is vertically inserted into the sample chamber. The receiving phase solution is then added to the receiving chamber to begin the extraction.

[0004] However, in actual use, the membrane solvent coated on the membrane is prone to diffuse into the solution at the interface during the extraction process. Since it is impossible to replenish the membrane solvent, the mass transfer process of the target analyte is hindered, the efficiency is reduced, and the separation and detection results are affected. Utility Model Content

[0005] The main objective of this invention is to provide an extraction device based on membrane solvents, which solves the problem that the membrane solvent coated on the membrane in existing membrane extraction devices easily diffuses into the solution during the extraction process, affecting the extraction efficiency.

[0006] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is as follows: An extraction device based on membrane solvent includes a receiving phase, a sample phase, and an organic phase disposed within a container. The receiving phase is used to receive the extracted product, and the sample phase is used to hold the sample to be extracted. The organic phase is located between the receiving phase and the sample phase; The organic phase includes two extraction membranes with a membrane solvent between them; The sample phase is extracted through an extraction membrane and a membrane solvent, and then enters the receiving phase to obtain the extracted product.

[0007] In a preferred embodiment, the sample phase is contained in a sample tube, which has a sample cavity inside. The receiving container is a receiving tube, and the receiving tube is equipped with a receiving cavity; The container for the organic phase is an organic cylinder, which contains an organic cavity. The sample chamber, receiving chamber, and organic chamber are separated by two extraction membranes.

[0008] In the preferred embodiment, the sample tube and the receiving tube are sealed at the ends away from the organic tube, and a connector tube is provided at the ends close to the organic tube. Both sides of the organic cylinder are provided with insertion slots, which are adapted to the insertion cylinder.

[0009] In the preferred embodiment, the container for receiving the phase, the sample phase, and the organic phase is a single, integral shell. The outer casing has two protective sleeves; An extraction plate is inserted inside the protective sleeve, and the extraction plate contains an extraction membrane. The outer shell is divided into a sample chamber, an organic chamber, and a receiving chamber by two extraction membranes.

[0010] In a preferred embodiment, the top of the extraction plate has a through hole for handheld use; Both sides of the extraction plate are equipped with sealing rings; The extraction plate has through holes inside, and the extraction membrane is placed inside the through holes.

[0011] In the preferred embodiment, the container is equipped with a feeding pipe and two inlet pipes; the inlet pipes are equipped with protective caps; The feed tube is connected to the organic solvent and is used to add and discharge the membrane solvent; The two inlet tubes are connected to the sample phase and the receiver, respectively. One tube is used to add and remove the sample, and the other tube is used to add the receiver liquid and remove the extracted product.

[0012] In the preferred embodiment, both the sample phase and the receiving phase are equipped with electrode structures to generate an electric field to increase the extraction efficiency.

[0013] In a preferred embodiment, the electrode structure includes a connector that connects to the container, and an electrode is disposed within the connector; The electrode passes through the insertion tube and enters the interior of the sample phase or the receiving phase; The electrodes are equipped with wires for connecting to an external power source.

[0014] This invention provides an extraction device based on membrane solvents. By adopting the above solution, it has the following beneficial effects: By forming independent organic phase regions through two extraction membranes, the membrane solvent is confined between the two membranes, effectively reducing diffusion loss; ensuring continuous and efficient mass transfer process, and solving the defect of traditional devices where membrane solvent cannot be replenished.

[0015] It offers two container structures: a detachable one and an integrated one. The detachable one allows for easy cleaning and replacement of each component, while the integrated one is simple to operate, has good sealing performance, and can be selected according to different extraction scenarios, making it highly adaptable.

[0016] By introducing an electric field-assisted structure, the electric field force is used to accelerate the mass transfer of charged target components. Combined with the efficient affinity of the membrane solvent, the extraction efficiency is improved compared with traditional devices, and the extraction time is significantly shortened. Attached Figure Description

[0017] The present invention will be further described below with reference to the accompanying drawings and embodiments: Figure 1 This is a schematic diagram of the structure of Embodiment 1 of this utility model; Figure 2 This is an exploded view of Embodiment 1 of this utility model; Figure 3 This is a cross-sectional view of Embodiment 1 of this utility model; Figure 4 This is a schematic diagram of the structure of Embodiment 2 of this utility model; Figure 5 This is a cross-sectional view of Embodiment 2 of this utility model.

[0018] In the picture: Sample cylinder 1, sample chamber 101, receiving cylinder 2, receiving chamber 201, organic cylinder 3, organic chamber 301, feeding pipe 302, inlet pipe 401, protective cover 402, electrode structure 5, insertion pipe 501, wire 502, electrode 503, insertion cylinder 601, insertion groove 602, extraction membrane 7, outer shell 8, protective sleeve 901, extraction plate 902, through hole 903, sealing ring 904, through hole 905. Detailed Implementation

[0019] In an embodiment of this application, an extraction device based on membrane solvent includes a receiving phase, an organic phase, and a sample phase arranged sequentially in a container, with the three phases distributed horizontally in layers. The receiving phase is used to receive the target product after extraction, the sample phase is used to hold the sample solution to be extracted, and the organic phase is located between the receiving phase and the sample phase, forming an isolation and mass transfer channel.

[0020] The organic phase consists of two extraction membranes 7 and a membrane solvent. The extraction membranes 7 are made of porous polypropylene. The two extraction membranes 7 are parallel and spaced apart, with a spacing of 5-10 mm. The space between them is filled with membrane solvent, such as n-octanol, 2-nitrophenyloctyl ether, etc., which are selected according to the affinity characteristics of the target component.

[0021] In use: The sample solution to be extracted is injected into the sample phase, the receiving liquid is injected into the receiving phase, and the membrane solvent is injected into the organic phase region between the two extraction membranes 7. Driven by the concentration difference, the target component in the sample phase first passes through the extraction membrane 7 closer to the sample phase and enters the membrane solvent, where the mass transfer process is completed. Then, it passes through the extraction membrane 7 closer to the receiving phase and enters the receiving phase, where it is finally enriched, resulting in the extracted product and achieving the separation of the target component.

[0022] In one embodiment, namely embodiment 1, as Figure 1 , 2 As shown in Figure 3, a separate container structure is adopted, specifically: The container for the sample phase is sample cylinder 1, which is preferably made of borosilicate glass and has a sample cavity 101 inside for containing the sample solution. The container for the receiving phase is receiving cylinder 2, which is also preferably made of borosilicate glass and has the same size as sample cylinder 1. It has a receiving cavity 201 inside for containing the receiving liquid and the extracted product. The container for the organic phase is organic cylinder 3, which is preferably made of polypropylene and is resistant to membrane solvent corrosion. Its inner diameter is the same as that of sample cylinder 1 and receiving cylinder 2. It has an organic cavity 301 inside for placing the two extraction membranes 7 and the membrane solvent.

[0023] The sample chamber 101, the receiving chamber 201 and the organic chamber 301 are separated by two extraction membranes 7. Specifically, extraction membranes 7 are provided on both ends of the organic cylinder 3. The edges of the extraction membranes 7 are sealed with epoxy resin to prevent the sample solution from mixing directly with the membrane solvent and to ensure the airtightness of the organic chamber 301.

[0024] In a further embodiment, the sample tube 1 and the receiving tube 2 are integrally sealed at the ends away from the organic tube 3, and an insert tube 601 is integrally formed at the ends close to the organic tube 3. The insert tube 601 is made of polypropylene. The two end faces of the organic tube 3 are provided with corresponding insertion grooves 602. The insertion grooves 602 are annular grooves with a depth adapted to the length of the insert tube 601. During connection, the insert tube 601 is inserted into the interior of the insertion groove 602 to complete the connection between the sample tube 1 and the receiving tube 2 and the organic tube 3. When the insert tube 601 is set, the extraction membrane 7 is set on the end face of the insert tube 601. After the insert tube 601 is inserted into the insertion groove 602, the extraction membrane 7 is located on both sides of the organic cavity 301.

[0025] The assembly and operation method of this split structure is as follows: First, fix the two extraction membranes 7 to the end faces of the insertion tubes 601 respectively. Then, insert the insertion tube 601 of the sample tube 1 into the insertion groove 602 on one side of the organic tube 3, and insert the insertion tube 601 of the receiving tube 2 into the insertion groove 602 on the other side of the organic tube 3 to complete the assembly of the three. Then, inject a quantitative membrane solvent into the organic chamber 301; inject the sample solution into the sample chamber 101 and inject the receiving liquid into the receiving chamber 201 to start the extraction process. After the extraction is completed, the sample tube 1, the receiving tube 2 or the organic tube 3 can be disassembled separately for easy cleaning, replacement of membrane solvent or collection of products.

[0026] In another embodiment, namely embodiment 2, as Figure 4 and 5 As shown, it adopts an integrated container structure, specifically: The container for receiving the phase, sample phase, and organic phase is a single shell 8, preferably made of polytetrafluoroethylene and hollow inside. Two protective sleeves 901 are symmetrically provided on the two side walls of the shell 8. The protective sleeves 901 are preferably made of polytetrafluoroethylene and are integrally formed with the shell 8. They have slots inside for inserting the extraction plate 902.

[0027] The extraction plate 902 is adapted to the slot of the protective sleeve 901, with its top located above the protective sleeve 901 for easy insertion and removal. The extraction plate 902 has a circular through hole 905 inside, in which the extraction membrane 7 is fixed and the edges are sealed by heat pressing to ensure airtightness. The top of the extraction plate 902 has a through hole 903 for easy insertion and removal by tweezers or fingers. Both sides of the extraction plate 902 are provided with sealing rings 904, which are preferably made of fluororubber and fit tightly against the inner wall of the slot of the protective sleeve 901 to prevent leakage of solutions between phases.

[0028] The outer casing 8 is divided into three chambers by the extraction membranes 7 on the two extraction plates 902: the area between the two extraction membranes 7 is the organic chamber 301, which is used to fill the membrane solvent; the area near the outside of one of the extraction plates 902 is the sample chamber 101, which is used to place the sample solution; and the area near the outside of the other extraction plate 902 is the receiving chamber 201, which is used to place the receiving liquid and the extracted product.

[0029] In use: First, insert the two extraction plates 902 into the protective sleeves 901 on both sides of the outer shell 8, ensuring that the sealing rings 904 are in place; inject the membrane solvent into the organic chamber 301 through the subsequently set feeding tube 302, and inject the sample solution into the sample chamber 101 and the receiving liquid into the receiving chamber 201 through the inlet tube 401; during the extraction process, the target component passes through the sample-side extraction membrane 7, the membrane solvent, and the receiving-side extraction membrane 7 in sequence into the receiving chamber 201; when it is necessary to replace the extraction membrane 7, simply pull out the old extraction plate 902 and insert the new extraction plate 902. The operation is simple and does not require disassembling the entire outer shell 8.

[0030] In a further embodiment, such as Figure 1 , 2 As shown in Figures 3, 4, and 5, both the separate and integrated container structures are equipped with a feed pipe 302 and two inlet pipes 401 for adding and discharging solutions of each phase. The feed pipe 302 is preferably made of polytetrafluoroethylene (PTFE), with one end connected to the organic cavity 301: in the separate structure, it connects to the side wall of the organic cylinder 3; in the integrated structure, it connects to the side wall of the outer shell 8 corresponding to the organic cavity 301. The other end extends to the outside of the container and is threaded for connecting a sealing cap or infusion tube. The function of the feed pipe 302 is to add and discharge membrane solvent: when the concentration of the membrane solvent decreases due to diffusion, the old membrane solvent can be discharged through the feed pipe 302, and new membrane solvent can be injected to ensure a stable concentration of membrane solvent in the organic phase and maintain efficient mass transfer; after extraction, the membrane solvent can also be discharged through the feed pipe 302 for easy container cleaning.

[0031] The two inlet tubes 401 are preferably made of polytetrafluoroethylene (PTFE). One inlet tube 401 is connected to the sample chamber 101: it is detachably connected to the side wall of the sample cylinder 1, and the integrally connected outer shell 8 corresponds to the side wall of the sample chamber 101. It is used to add the sample solution to be extracted into the sample chamber 101. After extraction, the remaining sample solution can also be discharged through this inlet tube 401. The other inlet tube 401 is connected to the receiving chamber 201: it is detachably connected to the side wall of the receiving cylinder 2, and the integrally connected outer shell 8 corresponds to the side wall of the receiving chamber 201. It is used to add the receiving liquid into the receiving chamber 201. After extraction, the extracted product is discharged through this inlet tube 401. Each inlet tube 401 has a protective cap 402 at its end. The protective cap 402 is preferably made of PTFE and is connected to the inlet tube 401 by threads to prevent dust and impurities from entering the chamber or the solution from evaporating during the extraction process.

[0032] In a further embodiment, to further improve extraction efficiency, both the sample phase and the receiving phase are provided with electrode structures 5, which promote mass transfer of charged target components by generating an electric field. Specifically, the electrode structure 5 includes a connector 501 connected to the container. The connector 501 is made of polytetrafluoroethylene, with one end connected to the sample chamber 101 or the receiving chamber 201 (connected to the side wall of the sample cylinder 1 or the receiving cylinder 2 in a separate configuration, and connected to the corresponding cavity side wall of the outer shell 8 in an integrated configuration), and the other end extending to the outside of the container.

[0033] An electrode 503 is provided inside the insertion tube 501. The electrode 503 is preferably made of platinum wire, which is chemically stable, not easily corroded by the solution, and has good conductivity. One end of the electrode 503 passes through the insertion tube 501 and enters the interior of the sample phase or receiving phase, with the end immersed in the solution. The other end is located outside the insertion tube 501 and is connected to a wire 502. The wire 502 is preferably a copper core polytetrafluoroethylene insulated wire, which is used to connect to an existing DC power supply.

[0034] The working method of electric field assisted extraction is as follows: During the extraction process, the electrode 503 of the sample phase and the electrode 503 of the receiving phase are connected to the positive and negative terminals of a DC power supply through wires 502, respectively. The connection method of positive and negative terminals is selected according to the charge properties of the target component. For example, if the target component is a cation, the sample phase is connected to the positive terminal and the receiving phase is connected to the negative terminal. The power supply is turned on and the output voltage is adjusted, preferably 5-20V, to form a stable electric field between the sample phase and the receiving phase. Under the action of the electric field force, the charged target component accelerates its movement towards the corresponding electrode, speeding up its passage through the extraction membrane 7 and the membrane solvent, thereby significantly improving the extraction efficiency and shortening the extraction time.

[0035] The above embodiments are merely preferred technical solutions of this utility model and should not be considered as limitations on this utility model. The protection scope of this utility model should be the technical solution described in the claims, including equivalent substitutions of the technical features described in the claims. That is, equivalent substitutions and improvements within this scope are also within the protection scope of this utility model.

Claims

1. An extraction device based on membrane solvent, characterized in that: It includes a receiving phase, a sample phase, and an organic phase located within the container. The receiving phase is used to receive the extracted product, and the sample phase is used to hold the extracted sample. The organic phase is located between the receiving phase and the sample phase; The organic phase includes two extraction membranes (7), with a membrane solvent between the two extraction membranes (7); The sample phase is extracted by the extraction membrane (7) and the membrane solvent and then enters the receiving phase to obtain the extracted product.

2. The membrane solvent-based extraction device according to claim 1, characterized in that: the sample The container for the phase is a sample tube (1), and the sample tube (1) is provided with a sample chamber (101). The receiving container is a receiving tube (2), and the receiving tube (2) is provided with a receiving cavity (201); The container for the organic phase is an organic cylinder (3), and an organic cavity (301) is provided inside the organic cylinder (3). The sample chamber (101), the receiving chamber (201), and the organic chamber (301) are separated by two extraction membranes (7).

3. The extraction device based on membrane solvent according to claim 2, characterized in that: The sample tube (1) and the receiving tube (2) are sealed at the ends away from the organic tube (3), and the end near the organic tube (3) is provided with a plug tube (601). Both sides of the organic cylinder (3) are provided with insertion slots (602), which are adapted to the insertion cylinder (601).

4. The extraction device based on membrane solvent according to claim 1, characterized in that: The container for receiving the phase, sample phase and organic phase is a single integrated shell (8); Two protective sleeves (901) are provided on the outer shell (8); An extraction plate (902) is inserted into the protective sleeve (901), and an extraction membrane (7) is built into the extraction plate (902). The outer shell (8) is divided into a sample chamber (101), an organic chamber (301) and a receiving chamber (201) by two extraction membranes (7).

5. The membrane solvent-based extraction device according to claim 4, characterized in that: The top of the extraction plate (902) has a through hole (903) for handheld use; Both sides of the extraction plate (902) are provided with sealing rings (904). The extraction plate (902) has a through hole (905) inside, and the extraction membrane (7) is located inside the through hole (905).

6. An extraction apparatus based on a membrane solvent according to any one of claims 1-5, characterized in that: The container is provided with a feeding pipe (302) and two inlet pipes (401); the inlet pipes (401) are provided with protective caps (402); The feed tube (302) is connected to the organic solvent and is used to add and discharge the membrane solvent; Two inlet tubes (401) are connected to the sample phase and the receiver, respectively. One tube is used to add and discharge the sample, and the other tube is used to add the receiver liquid and discharge the extracted product.

7. An extraction apparatus based on a membrane solvent according to any one of claims 1-5, characterized in that: Both the sample phase and the receiving phase are equipped with electrode structures (5) to generate an electric field to increase the extraction efficiency.

8. The membrane solvent-based extraction device according to claim 7, characterized in that: The electrode structure (5) includes a connector (501) connected to the container, and an electrode (503) is provided inside the connector (501). The electrode (503) passes through the insertion tube (501) and enters the interior of the sample phase or the receiving phase; The electrode (503) is equipped with a wire (502) for connecting to an external power source.

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