A small magnonic mixer and a small magnonic mixing system

Abstract

The utility model discloses a small -size magnetic son mixer and small -size magnetic son mixing system, small -size magnetic son mixer contains the jacket, and the both ends of jacket are installed with the feed pipe and the discharge pipe respectively, and is installed with the circulating medium inlet pipe and the circulating medium outlet pipe on the jacket respectively, and is connected with the feed branch pipe on the feed pipe, and the caliber of feed pipe is 1 / 4inch 1 / 2inch, and the caliber of discharge pipe is 1 / 4inch 1 / 2inch, stirring magnetic son, stirring magnetic son sets up in the inside of jacket, and the shape of stirring magnetic son is ellipsoidal or cylindrical, and the diameter of stirring magnetic son is 2mm 8mm, fixed part, and the inside wall of jacket is installed with a plurality of fixed parts, and small -size magnetic son mixing system contains the feed assembly, the discharge assembly, the magnetic force driver, the magnetic son mixer, the magnetic force driver sets up in the bottom of magnetic son mixer, the feed assembly is connected in the feed pipe, the discharge assembly is connected in the discharge pipe, and the circulating medium inlet pipe is connected with circulating medium outlet pipe through the pipeline.

Description

Technical Field

[0001] This utility model relates to the field of magnetic mixers, specifically to a small magnetic mixer and a small magnetic mixing system. Background Technology

[0002] In continuous chemical manufacturing processes for pharmaceuticals, mass and heat transfer have a significant impact on the reaction. Mass transfer is primarily achieved through stirring. Currently, various mixing equipment is developed and used by different companies, mainly falling into two categories: static and mechanical mixing. Examples include static mixers with an internal spiral shape that rely on fluid shear for mixing, and dynamic tubular reactors or small reaction vessels that use mechanical or magnetic drives for mixing. In the early stages of process development and pilot-scale production, due to the low material flow rate, ordinary static mixers cannot meet the requirements. Dynamic tubular reactors, on the other hand, are limited in their application due to their large size and high cost. Magnetic mixers are not commercially available and are generally custom-made. Currently, a common approach is to place a magnetic mixer inside a pipe, fix it with debris, and use electromagnetic drive to rotate the mixer and achieve mixing.

[0003] However, this type of magnetic mixer has problems such as inability to control temperature and ineffective fixation of the internal magnetic particles. Under the impact of fluid and pressure, the fixed object is prone to movement, and the magnetic particles are prone to accumulation, leading to blockage or poor stirring effect. It is not suitable for reaction occasions with strict temperature requirements. This utility model develops a jacketed design with spacers between the magnetic particles to relatively fix them and prevent accumulation due to fluid impact, effectively solving the above problems. Utility Model Content

[0004] The technical problem this invention aims to solve is that existing magnetic mixers suffer from issues such as the inability to effectively fix the internal magnetic particles. Under the impact of fluid and pressure, the fixing device is prone to movement, and the magnetic particles easily accumulate, leading to blockages or reduced stirring effect. This makes them unsuitable for reactions with strict temperature requirements. This invention provides a small magnetic mixer, a small magnetic mixing system, and a method for using the mixing system. It employs fixing components to secure the stirring magnetic particles in a fixed position within the jacket, preventing particle accumulation, providing strong impact resistance, ensuring mass transfer in the reaction, achieving effective temperature control in the mixing section, and guaranteeing heat transfer in the reaction. This compact device ensures effective mass and heat transfer in small-scale continuous reactions, avoiding... No stirring required Magnetic particle stacking is a simple and easy-to-use technology used to overcome the shortcomings of existing technologies.

[0005] To solve the above-mentioned technical problems, this utility model provides the following technical solution: In a first aspect, a small magnetic mixer includes a jacket, with a feed pipe and a discharge pipe respectively installed at both ends of the jacket, and a circulating medium inlet pipe and a circulating medium outlet pipe respectively installed on the jacket. A stirring magnet, wherein the stirring magnet is disposed inside the jacket; The jacket has multiple fixing components installed on its inner wall, with the stirring magnet between every two fixing components, and the multiple fixing components are equidistant from each other. The circulator is connected to the circulating medium inlet pipe and the circulating medium outlet pipe respectively via pipelines.

[0006] In the aforementioned small magnetic mixer, a feed branch pipe is connected to the feed pipe.

[0007] In the aforementioned small magnetic mixer, the diameter of the feed tube is 1 / 4 inch to 1 / 2 inch, and the diameter of the discharge tube is 1 / 4 inch to 1 / 2 inch. In the aforementioned small magnetic mixer, the stirring magnetic particle is ellipsoidal or cylindrical in shape.

[0008] In the aforementioned small magnetic mixer, the diameter of the stirring magnetic particle is 2mm-8mm.

[0009] In the aforementioned small magnetic mixer, a quartz glass plate is installed on the inner wall of the jacket. The fixing member is installed on the inner wall of the quartz glass plate by fixing screws. The elongated quartz glass plate can be used as a sight glass to observe the operation of the stirring magnetic particle. The quartz glass plate is detachable and can be removed for processing and cleaning if necessary during or after production. The quartz glass plate and the jacket are sealed with a sealing strip, preferably a PTFE sealing strip.

[0010] In a second aspect, a small magnetic mixing system includes a feeding assembly, a discharging assembly, a magnetic actuator, and the magnetic mixer described in any one of the first aspects; The magnetic actuator is located at the bottom of the magnetic mixer to drive the stirring magnet; The feeding assembly is connected to the feeding pipe; The discharge assembly is connected to the discharge pipe.

[0011] In the aforementioned small magnetic mixing system, the feeding assembly includes a feeding raw material and a precooling pipe connected in sequence. The discharge assembly includes a reaction pipe and a receiving bucket connected in sequence.

[0012] In the aforementioned small magnetic mixing system, the feeding assembly includes multiple sets of sequentially connected feeding raw materials and precooling pipes. The multiple precooling pipes are connected to the feeding pipe through multi-head connectors. Preferably, two sets of sequentially connected feeding raw materials and precooling pipes are provided. The discharge assembly includes a reaction pipe and a receiving bucket connected in sequence.

[0013] In the fluorination project, the existing static mixer was used for production, with a normal operating time of no more than 1.5 hours. The mixer and reaction pipeline were prone to blockage due to the accumulation of solids, which could not guarantee continuous production. The use of ordinary magnetic mixers alleviated the blockage, but blockage still occurred because the magnetic particles were not effectively fixed and were occasionally impacted by the fluid, causing them to accumulate and become unable to rotate, resulting in the accumulation of flocculent matter. In addition, the outlet temperature of the mixing section was 20°C, which exceeded the process range, resulting in a 4% increase in impurity levels and a decrease in yield. Using the small magnetic mixing system proposed in this application, the mixing section was circulated with a low-temperature medium, which allowed the outlet temperature of the mixing section to be controlled at around 5°C, with an impurity content of less than 1%. No blockage occurred, and the reaction was successfully completed.

[0014] Thirdly, a method of using a small magnetic particle hybrid system, comprising the following steps: Install the small magnetic hybrid system according to the above connection relationship; Turn on the magnetic actuator and set the rotation speed; Turn on the circulator and adjust it to the required process temperature; Continuous feeding and discharging of materials until production is complete.

[0015] The technical solution provided by the present invention, a small magnetic mixer and a small magnetic mixing system, has the following technical effects: The stirring magnet is fixed in place within the jacket using fasteners, preventing its accumulation and providing strong impact resistance. This ensures mass transfer during the reaction, achieves effective temperature control in the mixing section, and guarantees heat transfer. The compact design effectively ensures mass and heat transfer in small-scale continuous reactions, avoiding [further issues]. No stirring required Magnetic particle stacking has a simple structure and is easy to use. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the structure of a small magnetic mixer according to the present invention; Figure 2 This is a schematic diagram of the structure of the second embodiment of the present utility model; Figure 3 This is a structural schematic diagram of the third embodiment of the present utility model.

[0017] The reference numerals in the attached figures are as follows: Jacket 100, feeding assembly 200, discharging assembly 300, magnetic actuator 400, feeding pipe 101, discharging pipe 102, circulating medium inlet pipe 103, circulating medium outlet pipe 104, stirring magnet 105, fixing component 106, feeding branch pipe 107, quartz glass plate 108, fixing screw 109, feeding raw material 201, precooling pipe 202, reaction pipe 301, receiving bucket 302, circulator (not shown in the figure). Detailed Implementation

[0018] In order to make the technical means, inventive features, objectives and effects of the utility model easy to understand, the technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to specific illustrations. Obviously, the described embodiments are some embodiments of the utility model, but not all embodiments.

[0019] Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0020] It should be noted that the structures, proportions, sizes, etc., shown in the accompanying drawings of this specification are only used to complement the content disclosed in the specification for those skilled in the art to understand and read, and are not intended to limit the conditions under which this utility model can be implemented. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in the proportional relationships, or adjustments to the size, without affecting the effects and purposes that this utility model can produce, should still fall within the scope of the technical content disclosed in this utility model.

[0021] Meanwhile, the terms such as "upper", "lower", "left", "right", "middle" and "one" used in this specification are only for clarity of description and are not intended to limit the scope of implementation of this utility model. Changes or adjustments to their relative relationships, without substantially altering the technical content, should also be considered as within the scope of implementation of this utility model.

[0022] This invention relates to a small magnetic mixer and a small magnetic mixing system. The purpose is to use a fixing component to secure the stirring magnetic particle in a fixed position within the jacket, preventing particle accumulation, providing strong impact resistance, ensuring mass transfer in the reaction, achieving effective temperature control in the mixing section, and guaranteeing heat transfer in the reaction. This compact device ensures effective mass and heat transfer in small-scale continuous reactions, avoiding... No stirring required Magnetic particle stacking has a simple structure and is easy to use.

[0023] like Figure 1As shown in the first embodiment, a small magnetic mixer includes a jacket 100. A feed pipe 101 and a discharge pipe 102 are respectively installed at both ends of the jacket 100. A circulating medium inlet pipe 103 and a circulating medium outlet pipe 104 are respectively installed on the jacket 100. A feed branch pipe 107 is connected to the feed pipe 101. The diameter of the feed pipe 101 is 1 / 4 inch to 1 / 2 inch, and the diameter of the discharge pipe 102 is 1 / 4 inch to 1 / 2 inch. Stirring magnet 105 is disposed inside jacket 100. The stirring magnet 105 is ellipsoidal or cylindrical in shape and has a diameter of 2mm-8mm. The inner wall of the jacket 100 is equipped with multiple fasteners 106, and a stirring magnet 105 is provided between every two fasteners 106. The circulator is connected to the circulating medium inlet pipe 103 and the circulating medium outlet pipe 104 via pipelines.

[0024] The jacket 100 has a quartz glass plate 108 installed on its inner wall. The fastener 106 is installed on the inner wall of the quartz glass plate 108 by fixing screws 109. The long strip of quartz glass plate 108 can be used as a sight glass to observe the operation of the stirring magnet 105. The quartz glass plate 108 is detachable. If necessary during or after production, the quartz glass plate 108 can be removed for processing and cleaning. The quartz glass plate 108 and the jacket 100 are sealed with a sealing strip, preferably a PTFE sealing strip.

[0025] like Figure 2 As shown, in the second embodiment, a small magnetic mixing system includes a feeding assembly 200, a discharging assembly 300, a magnetic actuator 400, and a magnetic mixer of any one of the first aspects. The magnetic actuator 400 is located at the bottom of the magnetic mixer; The feeding assembly 200 is connected to the feeding pipe 101, and the feeding assembly 200 includes a feeding raw material 201 and a precooling pipe 202 connected in sequence. The discharge assembly 300 is connected to the discharge pipe 102. The discharge assembly 300 includes a reaction pipe 301 and a receiving tank 302 connected in sequence.

[0026] like Figure 3 As shown, in the third embodiment, a small magnetic mixing system includes a feeding assembly 200, a discharging assembly 300, a magnetic actuator 400, and a magnetic mixer of any one of the first aspects. The magnetic actuator 400 is located at the bottom of the magnetic mixer; The feeding assembly 200 is connected to the feeding pipe 101. The feeding assembly 200 includes multiple sets of feeding raw materials 201 and pre-cooling pipes 202 connected in sequence. The multiple pre-cooling pipes 202 are connected to the feeding pipe 101 through multi-head connectors. Preferably, there are two sets of feeding raw materials 201 and pre-cooling pipes 202 connected in sequence. The discharge assembly 300 is connected to the discharge pipe 102. The discharge assembly 300 includes a reaction pipe 301 and a receiving tank 302 connected in sequence.

[0027] Fourth embodiment, a method of using a small magnetic particle hybrid system, comprising the following steps: Install the small magnetic hybrid system according to the above connection relationship; Turn on the magnetic drive 400 and set the rotation speed; Turn on the circulator and adjust it to the required process temperature; Continuous feeding and discharging of materials until production is complete.

[0028] The general reaction process of a certain fluorine oxide substitution project is as follows: The reaction temperature of this process is 0~10℃. This reaction is a strongly exothermic reaction. Flocculent solids are generated at the moment when materials A and B come into contact. They gradually decrease and disappear with stirring. High requirements are placed on mixing and temperature control.

[0029] In summary, this utility model provides a small magnetic mixer and a small magnetic mixing system. It uses a fixing component to secure the stirring magnetic particle in a fixed position within the jacket, preventing particle accumulation, providing strong impact resistance, ensuring mass transfer in the reaction, achieving effective temperature control in the mixing section, and guaranteeing heat transfer in the reaction. This compact device ensures effective mass and heat transfer in small-scale continuous reactions, avoiding... No stirring required Magnetic particle stacking has a simple structure and is easy to use.

[0030] The specific embodiments of the utility model have been described above. It should be understood that the utility model is not limited to the specific embodiments described above, and the devices and structures not described in detail should be understood as being implemented in a manner common to the art; those skilled in the art can make various modifications or alterations within the scope of the claims, and make several simple deductions, modifications or substitutions, which do not affect the substantive content of the utility model.

Claims

1. A small magnetic mixer, characterized in that, It includes a jacket, with a feed pipe and a discharge pipe installed at both ends of the jacket, and a circulating medium inlet pipe and a circulating medium outlet pipe installed on the jacket. A stirring magnet, wherein the stirring magnet is disposed inside the jacket; The jacket has multiple fixing components installed on its inner wall, with the stirring magnet positioned between every two fixing components. The circulator is connected to the circulating medium inlet pipe and the circulating medium outlet pipe respectively via pipelines.

2. The miniature magnetic mixer according to claim 1, characterized in that, A feed branch pipe is connected to the feed pipe.

3. A small magnetic mixer according to claim 1, characterized in that, The feed tube has a diameter of 1 / 4 inch to 1 / 2 inch, and the discharge tube has a diameter of 1 / 4 inch to 1 / 2 inch.

4. A small magnetic mixer according to claim 1, characterized in that, The stirring magnet is ellipsoidal or cylindrical in shape.

5. A small magnetic mixer according to claim 1, characterized in that, The diameter of the stirring magnet is 2mm-8mm.

6. A miniature magnetic mixer according to claim 1, characterized in that, A quartz glass plate is installed on the inner wall of the jacket, and the fastener is installed on the inner wall of the quartz glass plate by fixing screws.

7. A small-scale magnetic particle hybrid system, characterized in that, It includes a feeding assembly, a discharging assembly, a magnetic actuator, and a magnetic mixer according to any one of claims 1-6; The magnetic actuator is disposed at the bottom of the magnetic mixer; The feeding assembly is connected to the feeding pipe; The discharge assembly is connected to the discharge pipe.

8. A small magnetic particle hybrid system according to claim 7, characterized in that, The feeding assembly includes a feeding raw material and a precooling pipe connected in sequence; The discharge assembly includes a reaction pipe and a receiving bucket connected in sequence.

9. A small magnetic particle hybrid system according to claim 7, characterized in that, The feeding assembly includes multiple sets of feeding raw materials and precooling pipes connected in sequence, and the multiple precooling pipes are connected to the feeding pipes through multi-head connectors; The discharge assembly includes a reaction pipe and a receiving bucket connected in sequence.

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