A homogenizing filling system for a compound sulfadiazine suspension

Abstract

The utility model discloses a kind of homogenization filling systems of compound sulfadiazine suspension, it is related to the production technology field of pharmaceutical preparation, including storage tank, the inside fixedly connected with baffle of storage tank, the upper surface of storage tank and baffle are rotatably connected with sleeve, the inside sliding of sleeve is provided with moving rod, the lower surface of storage tank is fixedly connected with liquid outlet pipe, the rod wall fixed sleeve of moving rod all have two pistons, two the piston is matched with liquid outlet pipe, the upper surface of storage tank is provided with driving mechanism, moving rod moves through driving mechanism. The utility model drives sleeve rotation to drive first, second stirring rod, realize that suspension in storage tank whole area is turned over, simultaneously driving mechanism synchronous drive moving rod and piston reciprocating motion, directly from tank bottom liquid outlet pipe quantitative filling, avoid the concentration difference caused by traditional first stirring medicine particle gradually settling after conveying mode.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical preparation production technology, specifically to a homogenization filling system for compound sulfadiazine suspension. Background Technology

[0002] Compound sulfadiazine suspension is a commonly used veterinary or human antibacterial drug preparation. Its main components are sulfadiazine and trimethoprim. Because drug particles in the suspension are prone to sedimentation and aggregation, insufficient homogenization or precipitation during filling can lead to uneven product concentration and affect efficacy.

[0003] Existing homogenization and filling systems for compound sulfadiazine suspensions mostly use a single stirring paddle for static stirring in the storage tank. The stirring range is limited to a local area inside the tank, and dead corners such as the bottom and walls of the tank are prone to forming sedimentation zones. At the same time, the stirring and filling of existing filling systems are mostly independent processes. They usually first stir and homogenize the suspension in the storage tank, and then transport it to the filling head through a pump. During the transportation process, drug particles will continue to settle, resulting in a difference in formulation concentration between the initial and later stages of filling. Utility Model Content

[0004] In view of the problems existing in the homogenization and filling system of the above-mentioned compound sulfadiazine suspension, this utility model is proposed.

[0005] Therefore, the purpose of this invention is to provide a homogenization filling system for compound sulfadiazine suspension, which solves the problem that in the usual process of first stirring and homogenizing the suspension in a storage tank and then pumping it to the filling head, drug particles will continue to settle during the transportation process, resulting in a difference in formulation concentration between the initial and later stages of filling.

[0006] To achieve the above objectives, this utility model provides the following technical solution: A homogenization and filling system for compound sulfadiazine suspension includes a storage tank. A partition is fixedly connected inside the storage tank. A sleeve is rotatably connected to the upper surface of the storage tank and the partition. A moving rod is slidably disposed inside the sleeve. A liquid outlet pipe is fixedly connected to the lower surface of the storage tank. Two pistons are fixedly fitted to the rod wall of the moving rod, and both pistons are matched with the liquid outlet pipe. A driving mechanism is disposed on the upper surface of the storage tank, and the moving rod moves via the driving mechanism. Multiple first stirring rods are symmetrically fixedly connected to the wall of the sleeve. An auxiliary stirring mechanism is symmetrically disposed on the outer surface of the sleeve. A transmission mechanism is disposed between the driving mechanism and the sleeve, and the driving mechanism drives the sleeve to rotate via the transmission mechanism.

[0007] Preferably, the drive mechanism includes two mounting plates, a first rotating rod, a pressure plate, an eccentric wheel, and a motor. The two mounting plates are symmetrically fixedly connected to the upper surface of the storage tank. The first rotating rod is rotatably connected between the two mounting plates. The eccentric wheel is fixedly sleeved on the rod wall of the first rotating rod. The pressure plate is fixedly connected to the upper end of the moving rod and fits against the side wall of the eccentric wheel. The motor is fixedly connected to one side of the mounting plate. One end of the first rotating rod passes through one side of the mounting plate and is fixedly connected to the output end of the motor.

[0008] Preferably, the transmission mechanism includes a second rotating rod, two bevel gears, a driving gear, and a driven gear. The second rotating rod is rotatably connected to the upper surface of the storage tank. The two bevel gears are respectively fixedly sleeved on one end of the first rotating rod and the second rotating rod, and the two bevel gears mesh with each other. The driving gear is fixedly sleeved on the lower end of the second rotating rod, and the driven gear is fixedly sleeved on the tube wall of the sleeve and meshes with the driving gear.

[0009] Preferably, the auxiliary stirring mechanism includes two L-shaped rods and multiple second stirring rods. The two L-shaped rods are symmetrically fixedly connected to the outer surface of the sleeve, and each second stirring rod is fixedly connected to the rod wall at one end of the corresponding L-shaped rod.

[0010] Preferably, two springs are symmetrically fixedly connected between the pressure plate and the storage tank.

[0011] Preferably, the lower end of the storage tank is inverted conical.

[0012] The technical effects and advantages provided by this utility model in the above technical solution are as follows: 1. This utility model drives the first and second stirring rods to rotate the drive sleeve, thereby turning the suspension in the storage tank over in the entire area. At the same time, the drive mechanism drives the moving rod and piston to move back and forth, and directly fills the liquid from the bottom outlet pipe of the tank in a quantitative manner, avoiding the concentration difference caused by the gradual sedimentation of drug particles in the traditional stirring and then conveying mode.

[0013] 2. This utility model achieves quantitative filling through the reciprocating motion of two pistons, eliminating the need for an additional metering pump. At the same time, the spring-assisted pressure plate resets, preventing filling interruptions caused by piston jamming. Attached Figure Description

[0014] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this utility model. For those skilled in the art, other drawings can be obtained based on these drawings.

[0015] Figure 1 This is a schematic diagram of the structure of this utility model; Figure 2 For the present utility model Figure 1 A sectional view; Figure 3 For the present utility model Figure 1 A three-dimensional structural diagram of the eccentric wheel.

[0016] Explanation of reference numerals in the attached figures: 1. Storage tank, 2. Baffle plate, 3. Sleeve, 4. Moving rod, 5. Liquid outlet pipe, 6. Piston, 7. First stirring rod, 8. Mounting plate, 9. First rotating rod, 10. Pressure plate, 11. Eccentric wheel, 12. Motor, 13. Second rotating rod, 14. Bevel gear, 15. Driving gear, 16. Driven gear, 17. L-shaped rod, 18. Second stirring rod, 19. Spring. Detailed Implementation

[0017] To enable those skilled in the art to better understand the technical solution of this utility model, the present utility model will be further described in detail below with reference to the accompanying drawings.

[0018] This utility model discloses a homogenization filling system for compound sulfadiazine suspension.

[0019] This utility model provides, for example Figure 1-3 The homogenization and filling system for a compound sulfadiazine suspension shown includes a storage tank 1. A partition 2 is fixedly connected inside the storage tank 1. A sleeve 3 is rotatably connected to the upper surfaces of the storage tank 1 and the partition 2. A moving rod 4 is slidably arranged inside the sleeve 3. An outlet pipe 5 is fixedly connected to the lower surface of the storage tank 1. Each of the fixed sleeves on the rod wall of the moving rod 4 has two pistons 6, and both pistons 6 are matched with the outlet pipe 5. A driving mechanism is provided on the upper surface of the storage tank 1, and the moving rod 4 moves through the driving mechanism. Multiple first stirring rods 7 are symmetrically fixedly connected to the wall of the sleeve 3. An auxiliary stirring mechanism is symmetrically arranged on the outer surface of the sleeve 3. A transmission mechanism is provided between the driving mechanism and the sleeve 3, and the driving mechanism drives the sleeve 3 to rotate through the transmission mechanism.

[0020] like Figure 1-3 As shown, the drive mechanism includes two mounting plates 8, a first rotating rod 9, a pressure plate 10, an eccentric wheel 11, and a motor 12. The two mounting plates 8 are symmetrically fixedly connected to the upper surface of the storage tank 1. The first rotating rod 9 is rotatably connected between the two mounting plates 8. The eccentric wheel 11 is fixedly sleeved on the rod wall of the first rotating rod 9. The pressure plate 10 is fixedly connected to the upper end of the moving rod 4 and fits against the side wall of the eccentric wheel 11. The motor 12 is fixedly connected to one side of the mounting plate 8. One end of the first rotating rod 9 passes through one side of the mounting plate 8 and is fixedly connected to the output end of the motor 12. Two springs 19 are symmetrically fixedly connected between the pressure plate 10 and the storage tank 1.

[0021] When the first rotating rod 9 rotates, the eccentric wheel 11 on its rod wall rotates synchronously. The eccentric structure of the eccentric wheel squeezes the pressure plate 10, pushing the pressure plate downward, which in turn drives the moving rod 4 to slide inside the sleeve 3. When the long radius end of the eccentric wheel moves away from the pressure plate, the spring 19 between the pressure plate and the storage tank 1 releases its elastic potential energy, pulling the pressure plate upward to reset, and driving the moving rod to rise synchronously, forming the reciprocating motion of the two pistons 6. When the two pistons 6 move upward, the upper piston moves out of the liquid outlet pipe 5, and at this time the liquid medicine enters the interior of the liquid outlet pipe 5. Then, when the two pistons move downward, the lower piston moves out of the liquid outlet pipe 5, and the upper piston moves back into the liquid outlet pipe, so that the liquid medicine inside the liquid outlet pipe can flow out, and the amount of liquid medicine flowing out is constant to the size of the area between the two pistons.

[0022] like Figure 1-2 As shown, the transmission mechanism includes a second rotating rod 13, two bevel gears 14, a driving gear 15, and a driven gear 16. The second rotating rod 13 is rotatably connected to the upper surface of the storage tank 1. The two bevel gears 14 are respectively fixedly sleeved on one end of the first rotating rod 9 and the second rotating rod 13, and the two bevel gears 14 mesh with each other. The driving gear 15 is fixedly sleeved on the lower end of the rod wall of the second rotating rod 13. The driven gear 16 is fixedly sleeved on the tube wall of the sleeve 3 and meshes with the driving gear 15. The auxiliary stirring mechanism includes two L-shaped rods 17 and multiple second stirring rods 18. The two L-shaped rods 17 are symmetrically fixedly connected to the outer surface of the sleeve 3, and each second stirring rod 18 is fixedly connected to the rod wall of one end of the corresponding L-shaped rod 17.

[0023] The motor 12 is started, and its output end drives the first rotating rod 9 to rotate between the two mounting plates 8. The bevel gear 14 at one end of the first rotating rod meshes with the bevel gear of the second rotating rod 13, converting horizontal power into vertical power, which drives the second rotating rod to rotate on the upper surface of the storage tank 1. The driving gear 15 at the lower end of the second rotating rod meshes with the driven gear 16 on the sleeve 3, driving the sleeve to rotate stably between the storage tank and the partition 2. Subsequently, multiple first stirring rods 7 on the sleeve wall rotate synchronously with the sleeve, agitating the suspension in the middle layer of the storage tank. At the same time, the L-shaped rod 17 on the outer surface of the sleeve drives the second stirring rod 18 to rotate. The L-shaped structure can extend to the bottom and near the tank wall of the storage tank, turning the drug particles deposited at the bottom of the tank to the upper layer, while scraping off the particles attached to the tank wall to avoid the formation of sedimentation dead zones.

[0024] like Figure 1-2 As shown, the lower end of storage tank 1 is inverted cone shape.

[0025] The lower end of storage tank 1 is inverted cone shape. Under the action of gravity, the suspension converges to the outlet pipe 5 at the center of the tank bottom, thus avoiding the presence of residual suspension at the bottom of the tank.

[0026] The foregoing description only illustrates certain exemplary embodiments of the present invention. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A homogenization and filling system for a compound sulfadiazine suspension, comprising a storage tank (1), characterized in that, The storage tank (1) is fixedly connected to a partition (2). The upper surfaces of the storage tank (1) and the partition (2) are rotatably connected to a sleeve (3). A moving rod (4) is slidably arranged inside the sleeve (3). A liquid outlet pipe (5) is fixedly connected to the lower surface of the storage tank (1). The moving rod (4) has two pistons (6) on its fixed sleeve wall. Both pistons (6) are matched with the liquid outlet pipe (5). A driving mechanism is provided on the upper surface of the storage tank (1). The moving rod (4) moves through the driving mechanism. Multiple first stirring rods (7) are symmetrically fixedly connected to the wall of the sleeve (3). An auxiliary stirring mechanism is symmetrically arranged on the outer surface of the sleeve (3). A transmission mechanism is provided between the driving mechanism and the sleeve (3). The driving mechanism drives the sleeve (3) to rotate through the transmission mechanism.

2. The homogenization and filling system for compound sulfadiazine suspension according to claim 1, characterized in that, The drive mechanism includes two mounting plates (8), a first rotating rod (9), a pressure plate (10), an eccentric wheel (11), and a motor (12). The two mounting plates (8) are symmetrically fixedly connected to the upper surface of the storage tank (1). The first rotating rod (9) is rotatably connected between the two mounting plates (8). The eccentric wheel (11) is fixedly sleeved on the rod wall of the first rotating rod (9). The pressure plate (10) is fixedly connected to the upper end of the moving rod (4) and fits against the side wall of the eccentric wheel (11). The motor (12) is fixedly connected to one side of the mounting plate (8). One end of the first rotating rod (9) passes through one side of the mounting plate (8) and is fixedly connected to the output end of the motor (12).

3. The homogenization and filling system for compound sulfadiazine suspension according to claim 1, characterized in that, The transmission mechanism includes a second rotating rod (13), two bevel gears (14), a driving gear (15), and a driven gear (16). The second rotating rod (13) is rotatably connected to the upper surface of the storage tank (1). The two bevel gears (14) are respectively fixedly sleeved on one end of the first rotating rod (9) and the second rotating rod (13), and the two bevel gears (14) mesh with each other. The driving gear (15) is fixedly sleeved on the lower end of the second rotating rod (13), and the driven gear (16) is fixedly sleeved on the tube wall of the sleeve (3) and meshes with the driving gear (15).

4. The homogenization and filling system for compound sulfadiazine suspension according to claim 1, characterized in that, The auxiliary stirring mechanism includes two L-shaped rods (17) and multiple second stirring rods (18). The two L-shaped rods (17) are symmetrically fixedly connected to the outer surface of the sleeve (3), and each second stirring rod (18) is fixedly connected to the rod wall at one end of the corresponding L-shaped rod (17).

5. The homogenization and filling system for compound sulfadiazine suspension according to claim 2, characterized in that, Two springs (19) are symmetrically fixedly connected between the pressure plate (10) and the storage tank (1).

6. The homogenization and filling system for compound sulfadiazine suspension according to claim 1, characterized in that, The lower end of the storage tank (1) is inverted cone shape.

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