A cell cryopreservation liquid dispenser
Patent Information
- Application Number
- CN202521883902.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-02
- Publication Date
- 2026-10-23
- Estimated Expiration
- 2035-09-02
AI Technical Summary
该专利文件在分装箱内的细胞冻存液长时间存放或分装过程中,由于对细胞冻存液是由多种物质混合制成,可能会出现沉淀或分层现象,进而导致细胞冻存液不均匀,从而影响细胞的活性和复苏效果
[0011]与现有技术相比的有益效果如下:通过第一电机驱动转板以第一转柱为轴转动,进而带动滑动板以第一转柱为轴以转板为半径转动,从而通过橡胶环带动分装桶做圆周运动,使得细胞冻存液在分装桶内部进行上下左右摇晃,通过搅拌轴对分装桶内的细胞冻存液进行搅拌,通过外部摇晃和内部搅拌的双重作用,确保细胞冻存液在分装过程中始终保持均匀,防止沉淀,提高细胞的活性和复苏效果。
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Figure CN224882426U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of cell cryopreservation technology, and in particular to a cell cryopreservation solution dispenser. Background Technology
[0002] Cell cryopreservation solution is a special liquid used to preserve cells at low temperatures. It mainly consists of basal culture medium, serum or serum substitutes and cryoprotectants. The aliquoting of cell cryopreservation solution is a key step in the cell cryopreservation process. According to the patent document with publication number CN219565554U, the patent document describes a method where a piston plate is moved downward by a driving cylinder, thereby pressing the cryopreservation fluid into the outlet pipe and applying pressure to the pressure relief solenoid valve, causing the pressure relief solenoid valve to open. The cryopreservation fluid then flows from the outlet pipe into the container, achieving quantitative dispensing. During the dispensing process, the piston plate moves the first and second magnet blocks downward, which in turn moves the indicator plate downward. The moving indicator plate indicates the scale through the indicator pin, thus displaying the remaining amount of cryopreservation fluid in the dispensing box. The cryopreservation fluid in the dispensing box is replenished through the filling pipe. The patent document states that during the long-term storage or repackaging of cell cryopreservation solution in the dispensing box, precipitation or stratification may occur because the cell cryopreservation solution is made of a mixture of various substances, which may lead to uneven cell cryopreservation solution and thus affect cell activity and recovery effect. Utility Model Content
[0003] The purpose of this invention is to provide a cell cryopreservation solution dispenser in order to solve the above-mentioned problems.
[0004] This utility model achieves the above objectives through the following technical solutions: A cell cryopreservation solution dispenser includes a base, a dispensing cup on the top front side of the base, a support plate fixed to the top rear side of the base, a dispensing container on the front side of the support plate, and a shaking mechanism located between the dispensing container and the support plate. The shaking mechanism includes a rotating plate, one rear end of which is rotatably connected to the top of a support plate, and the other front end of which is rotatably connected to a sliding plate. A rotating rod is rotatably connected to the bottom of the support plate, and a guide rod is fixed to the top of the rotating rod. The sliding plate is slidably connected to the outside of the guide rod, and a rubber ring for placing the dispensing barrel is fixed to the front of the sliding plate.
[0005] Preferably, a feed pipe is fixed to the top of the dispensing barrel, and a feed solenoid valve is fixed inside the feed pipe; a discharge pipe is fixed to the bottom of the dispensing barrel, and a discharge solenoid valve is fixed inside the discharge pipe.
[0006] Preferably, a stirring shaft is rotatably connected inside the dispensing tank, and a second motor is fixedly installed at the input end of the stirring shaft.
[0007] Preferably, a first motor is fixed to the rear side of the support plate, and a first rotating column fixed to the rear side of one end of the rotating plate is fixedly connected to the rotating shaft of the first motor.
[0008] Preferably, a rotating groove is provided on the rear side of the sliding plate, and a second rotating column that cooperates with the rotating groove of the sliding plate is fixed on the front side of the other end of the rotating plate.
[0009] Preferably, the sliding plate has a circular hole for the guide rod to pass through.
[0010] Preferred configuration: The dispensing container is inserted into a rubber ring, and the stirring shaft consists of a stirring rod and several stirring blades.
[0011] The beneficial effects compared with the existing technology are as follows: The first motor drives the rotating plate to rotate around the first rotating column as the axis, which in turn drives the sliding plate to rotate around the first rotating column as the axis and the rotating plate as the radius. This causes the dispensing container to make a circular motion through the rubber ring, so that the cell cryopreservation solution shakes up and down and left and right inside the dispensing container. The stirring shaft stirs the cell cryopreservation solution in the dispensing container. Through the dual action of external shaking and internal stirring, the cell cryopreservation solution is kept uniform throughout the dispensing process, preventing precipitation and improving cell activity and recovery effect. Attached Figure Description
[0012] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0013] Figure 1 This is a schematic diagram of the structure of a cell cryopreservation solution dispenser according to the present invention; Figure 2 This is a front view of a cell cryopreservation solution dispenser according to this utility model; Figure 3 yes Figure 2 A sectional view at point AA; Figure 4 This is a schematic diagram of the shaking mechanism of a cell cryopreservation solution dispenser according to this utility model; Figure 5 This is a schematic diagram of the rotating plate structure of a cell cryopreservation solution dispenser according to the present invention; Figure 6 This is a schematic diagram of the sliding plate and rubber ring structure of a cell cryopreservation solution dispenser according to this utility model; Figure 7 This is a schematic diagram of the rotating rod and guide rod structure of a cell cryopreservation solution dispenser according to this utility model; Figure 8This is a schematic diagram of the stirring shaft and the second motor structure of a cell cryopreservation solution dispenser according to this utility model.
[0014] The annotations in the attached figures are explained as follows: 1. Base; 2. Support plate; 3. Dispensing bucket; 4. Dispensing cup; 5. Shaking mechanism; 501. Rotating plate; 502. First motor; 503. Sliding plate; 504. Rotating rod; 505. Guide rod; 506. Rubber ring; 6. Feed pipe; 7. Discharge pipe; 8. Stirring shaft; 9. Second motor. Detailed Implementation
[0015] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances. All electrical components mentioned in this document are electrically connected to an external main controller and 220V AC mains power, and the main controller can be a conventionally known device such as a computer that provides control.
[0016] The present invention will be further described below with reference to the accompanying drawings: like Figures 1-8 As shown, a cell cryopreservation solution dispenser includes a base 1, a dispensing cup 4 on the top front side of the base 1, a support plate 2 fixed on the top rear side of the base 1, a dispensing container 3 on the front side of the support plate 2, and a shaking mechanism 5 located between the dispensing container 3 and the support plate 2.
[0017] In this embodiment: the shaking mechanism 5 includes a rotating plate 501. One rear end of the rotating plate 501 is rotatably connected to the top of the support plate 2. The front end of the other rotating plate 501 is rotatably connected to a sliding plate 503. A rotating groove is provided on the rear side of the sliding plate 503. A second rotating column that mates with the rotating groove of the sliding plate 503 is fixed on the front side of the other rotating plate 501. A rotating rod 504 is rotatably connected to the bottom of the support plate 2. A guide rod 505 is fixed on the top of the rotating rod 504. The sliding plate 503 is slidably connected to the outside of the guide rod 505. A circular hole is provided in the sliding plate 503 for the guide rod 505 to pass through. A rubber ring 506 for placing the dispensing barrel 3 is fixed on the front side of the sliding plate 503. The first motor 502 drives the rotating plate 501 to rotate around the first rotating column as the axis, which in turn drives the sliding plate 503 to rotate around the first rotating column as the axis and the rotating plate 501 as the radius. This causes the dispensing tank 3 to make a circular motion through the rubber ring 506, so that the cell cryopreservation solution shakes up and down and left and right inside the dispensing tank 3 to prevent sedimentation. During this process, the sliding plate 503 moves along the outside of the guide rod 505 and drives the guide rod 505 to rotate around the rotating rod 504 as the axis. The guide rod 505 slides in the circular hole, and the second rotating column rotates in the rotating groove of the sliding plate 503. This ensures that the dispensing tank 3 is in the state of the inlet pipe 6 facing upward and the outlet pipe 7 facing downward during the circular motion, which is convenient for dispensing.
[0018] In this embodiment: a feed pipe 6 is fixed to the top of the dispensing tank 3, and a feed solenoid valve is fixed inside the feed pipe 6. A discharge pipe 7 is fixed to the bottom of the dispensing tank 3, and a discharge solenoid valve is fixed inside the discharge pipe 7. A stirring shaft 8 is rotatably connected inside the dispensing tank 3. A second motor 9 is fixedly installed at the input end of the stirring shaft 8. The dispensing tank 3 is inserted into a rubber ring 506. The stirring shaft 8 consists of a stirring rod and several stirring blades. The opening and closing of the feed pipe 6 is controlled by the feed solenoid valve, and the cell cryopreservation solution in the dispensing tank 3 is replenished through the feed pipe 6. The opening and closing of the discharge pipe 7 is controlled by the discharge solenoid valve, and the cell cryopreservation solution in the dispensing tank 3 is discharged into the dispensing cup 4 through the discharge pipe 7. The stirring shaft 8 is driven to rotate by the second motor 9, and the several stirring blades of the stirring shaft 8 stir the cell cryopreservation solution in the dispensing tank 3 to make it more uniform.
[0019] Working principle: The cell cryopreservation solution in the dispensing tank 3 is replenished through the feed pipe 6 by opening the feed solenoid valve. The first motor 502 drives the rotating plate 501 to rotate around the first rotating column, which in turn drives the sliding plate 503 to rotate around the first rotating column with the rotating plate 501 as the radius. This, in turn, causes the dispensing tank 3 to move in a circular motion via the rubber ring 506, making the cell cryopreservation solution shake up and down and left and right inside the dispensing tank 3 to prevent sedimentation. The second motor 9 drives the stirring shaft 8 to rotate, and the stirring blades of the stirring shaft 8 then move against the dispensing tank. The cell cryopreservation solution in container 3 is stirred to make it more homogeneous. During this process, the sliding plate 503 moves along the outside of the guide rod 505 and drives the guide rod 505 to rotate around the rotating rod 504. The guide rod 505 slides in the circular hole, and the second rotating column rotates in the rotating groove of the sliding plate 503. This ensures that the feed pipe 6 is facing upward and the discharge pipe 7 is facing downward during the circular motion of the dispensing container 3. The discharge solenoid valve is opened, and the cell cryopreservation solution in the dispensing container 3 is discharged into the dispensing cup 4 through the discharge pipe 7, thus completing the dispensing.
[0020] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model.
Claims
1. A cell cryopreservation solution dispenser, comprising a base (1), a dispensing cup (4) provided on the front top of the base (1), a support plate (2) fixed on the rear top of the base (1), and a dispensing container (3) provided on the front side of the support plate (2), characterized in that: It also includes a shaking mechanism (5), which is located between the dispensing barrel (3) and the support plate (2); The shaking mechanism (5) includes a rotating plate (501), one end of which is rotatably connected to the top of the support plate (2), and the other end of which is rotatably connected to a sliding plate (503). The bottom of the support plate (2) is rotatably connected to a rotating rod (504), and a guide rod (505) is fixed at the top of the rotating rod (504). The sliding plate (503) is slidably connected to the outside of the guide rod (505), and a rubber ring (506) for placing the dispensing barrel (3) is fixed at the front of the sliding plate (503).
2. The cell cryopreservation solution dispenser according to claim 1, characterized in that: The top of the dispensing barrel (3) is fixed with a feed pipe (6), and a feed solenoid valve is fixed inside the feed pipe (6). The bottom of the dispensing barrel (3) is fixed with a discharge pipe (7), and a discharge solenoid valve is fixed inside the discharge pipe (7).
3. The cell cryopreservation solution dispenser according to claim 1, characterized in that: The dispensing tank (3) is rotatably connected to a stirring shaft (8), and a second motor (9) is fixedly installed at the input end of the stirring shaft (8).
4. The cell cryopreservation solution dispenser according to claim 1, characterized in that: The first motor (502) is fixed to the rear side of the support plate (2), and the first rotating column, which is fixedly connected to the rotating shaft of the first motor (502), is fixed to the rear side of one end of the rotating plate (501).
5. A cell cryopreservation solution dispenser according to claim 1, characterized in that: A rotating groove is provided on the rear side of the sliding plate (503), and a second rotating column that cooperates with the rotating groove of the sliding plate (503) is fixed on the front side of the other end of the rotating plate (501).
6. A cell cryopreservation solution dispenser according to claim 1, characterized in that: The sliding plate (503) has a circular hole for the guide rod (505) to pass through.
7. A cell cryopreservation solution dispenser according to claim 3, characterized in that: The dispensing container (3) is inserted into the rubber ring (506), and the stirring shaft (8) consists of a stirring rod and several stirring blades.
Citation Information
Patent Citations
Cell cryopreservation liquid subpackaging device
CN219565554U