A liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure
Patent Information
- Application Number
- CN202522546655.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-01
- Publication Date
- 2026-10-23
- Estimated Expiration
- 2035-12-01
AI Technical Summary
[0002]多肽是由多个氨基酸通过肽键连接形成的具有生物活性的小分子化合物,广泛应用于医药研发、临床诊断、生物工程等领域,液体多肽溶液在储存和运输过程中,其稳定性易受外界环境因素影响,如温度波动、氧气氧化、微生物污染等,均可能导致多肽分子结构破坏、活性丧失,进而影响其应用效果;
[0010]综上所述,本实用新型的技术效果和优点:该具有防泄漏与多肽稳定性保护结构的液体多肽储存罐,通过防护外壳、保温层和保存罐组成罐体,可以有效的对存储在保存罐内部的多肽进行保护,防护外壳和保存罐之间设置的保温层可以对保存罐内部的温度进行保温,并且在保存罐的内部填充氮气,从而有效的防止多肽与氧气接触,进而有效的对多肽进行保护,使多肽可以长期储存。
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Figure CN224882785U_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of biological reagent storage technology, specifically, it relates to a liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure. Background Technology
[0002] Peptides are small molecule compounds with biological activity formed by multiple amino acids linked by peptide bonds. They are widely used in pharmaceutical research and development, clinical diagnosis, bioengineering and other fields. During storage and transportation, the stability of liquid peptide solutions is easily affected by external environmental factors, such as temperature fluctuations, oxygen oxidation, and microbial contamination, which may lead to the destruction of peptide molecular structure and loss of activity, thereby affecting their application effect. Existing liquid peptide storage tanks mostly use a single sealing ring or threaded seal. After long-term use, leakage is likely to occur due to aging of the seals and assembly errors. The risk of leakage increases significantly, especially during transportation or pressure changes, resulting in peptide loss and cross-contamination. Furthermore, the storage tanks lack a targeted stability protection mechanism, making peptides prone to precipitation due to low-temperature instability, oxidative degradation, or uneven local concentration, which makes it difficult to meet the requirements for long-term storage. To address the aforementioned issues, this application proposes a liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure. Utility Model Content
[0003] To address the problems in related technologies, this utility model proposes a liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure to overcome the aforementioned technical problems existing in the prior art.
[0004] To achieve the above objectives, the present invention adopts the following technical solution: A liquid peptide storage tank with a leak-proof and peptide stability protection structure includes a tank body, a sealing component on the top of the tank body, the tank body including a protective shell, an insulation layer and a storage tank, an isolation groove between the protective shell and the storage tank, the side of the protective shell near the storage tank being attached to the insulation layer, and a liquid inlet on the top of the protective shell.
[0005] Preferably, a support column is fixedly connected to the inner bottom of the protective shell, and a limiting ring is fixedly connected to the side of the support column near the storage container, with the inner sidewall of the limiting ring fitting against the bottom of the storage container.
[0006] Preferably, the outer wall of the protective shell is provided with an air extraction port, the air extraction port is connected to the isolation groove, and a flange is provided at the end of the air extraction port away from the protective shell.
[0007] Preferably, the sealing assembly includes a can lid that fits against the outer wall of the liquid inlet, a sealing plug that is fixedly connected to the bottom center of the can lid, the outer wall of the sealing plug being adapted to the inner wall of the liquid inlet, and the outer wall of the liquid inlet having a threaded groove.
[0008] Preferably, the can lid is threadedly connected to the liquid inlet via a threaded groove, and a sealing ring and a sealing gasket are fixedly connected to the inner side wall of the liquid inlet.
[0009] Preferably, the inner wall of the liquid inlet is provided with a telescopic groove, a first spring is fixedly connected inside the liquid inlet, an inclined block is fixedly connected to the end of the first spring away from the liquid inlet, a squeezing column is fixedly connected to the top of the inclined block, a positioning frame is attached to the bottom of the inclined block, a second spring is fixedly connected to the inner wall of the positioning frame, a positioning plate is fixedly connected to the end of the second spring away from the positioning frame, the positioning plate is fixedly connected to the liquid inlet, and a telescopic opening is provided on the inner wall of the liquid inlet.
[0010] In summary, the technical effects and advantages of this utility model are as follows: This liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure, consisting of a protective shell, an insulation layer, and a storage tank, can effectively protect the polypeptides stored inside the storage tank. The insulation layer between the protective shell and the storage tank can keep the temperature inside the storage tank warm, and the storage tank is filled with nitrogen gas, thereby effectively preventing the polypeptides from coming into contact with oxygen, thus effectively protecting the polypeptides and allowing them to be stored for a long time. Attached Figure Description
[0011] Figure 1 This is a three-dimensional structural diagram of the present invention; Figure 2 This is a schematic diagram of the sealing plug and related structures of this utility model; Figure 3 This is a schematic diagram of the positioning frame and related structures of this utility model; Figure 4 This is a schematic diagram of the storage container and related structures of this utility model.
[0012] In the diagram: 1. Tank body; 101. Protective outer shell; 102. Isolation groove; 103. Insulation layer; 104. Storage tank; 105. Support column; 106. Limiting ring; 107. Air extraction port; 108. Liquid inlet; 2. Sealing assembly; 201. Tank lid; 202. Sealing plug; 203. Threaded groove; 204. Telescopic groove; 205. First spring; 206. Inclined block; 207. Extrusion column; 208. Positioning frame; 209. Second spring; 210. Positioning plate; 211. Telescopic port; 212. Sealing ring; 213. Sealing gasket. Detailed Implementation
[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.
[0014] Reference Figure 1-4 A liquid peptide storage tank with a leak-proof and peptide stability protection structure includes a tank body 1, a sealing component 2 on the top of the tank body 1, a protective shell 101, an insulation layer 103, and a storage tank 104. An isolation groove 102 is provided between the protective shell 101 and the storage tank 104. The side of the protective shell 101 near the storage tank 104 is in contact with the insulation layer 103. A liquid inlet 108 is provided on the top of the protective shell 101. The sealing component 2 on the top of the tank body 1 can prevent peptide leakage and effectively protect the peptide stored inside the tank body 1. Nitrogen gas is filled inside the storage tank 104 to prevent the peptide from contacting oxygen, thus effectively protecting the peptide. The sealing component 2 on the top of the liquid inlet 108 can seal the tank body 1, thereby effectively protecting the peptide and preventing leakage.
[0015] Reference Figure 4 A support column 105 is fixedly connected to the inner bottom of the protective shell 101. A limiting ring 106 is fixedly connected to the side of the support column 105 near the storage container 104. The inner side wall of the limiting ring 106 is in contact with the bottom of the storage container 104. The limiting ring 106 is supported by the support column 105 fixedly connected to the inner bottom of the protective shell 101. The limiting ring 106 is in contact with the bottom of the storage container 104, which can effectively support the storage container 104 and prevent the storage container 104 from shaking.
[0016] Reference Figure 1-2 The outer wall of the protective shell 101 is provided with an air extraction port 107, which is connected to the isolation tank 102. The end of the air extraction port 107 away from the protective shell 101 is provided with a flange. The gas in the isolation tank 102 is extracted through the air extraction port 107 installed on the outer wall of the protective shell 101, so that the inside of the isolation tank 102 tends to be a vacuum state, thereby effectively keeping the storage tank 104 warm.
[0017] Reference Figure 2The sealing assembly 2 includes a can lid 201 that fits against the outer wall of the liquid inlet 108. A sealing plug 202 is fixedly connected to the bottom center of the can lid 201. The outer wall of the sealing plug 202 is adapted to the inner wall of the liquid inlet 108. A threaded groove 203 is provided on the outer wall of the liquid inlet 108. The can lid 201 can be threadedly connected to the outer wall of the liquid inlet 108 through the threaded groove 203 on the outer wall of the liquid inlet 108 and the can lid 201, so that the sealing plug 202 can enter the interior of the liquid inlet 108 to seal it, thereby preventing peptide leakage.
[0018] Reference Figure 3 The can lid 201 is threadedly connected to the liquid inlet 108 via the threaded groove 203. A sealing ring 212 and a sealing gasket 213 are fixedly connected to the inner wall of the liquid inlet 108. The sealing ring 212 and the sealing gasket 213 installed on the inner wall of the liquid inlet 108 fit together with the sealing plug 202, which can effectively seal the liquid inlet 108, preventing oxygen from entering and effectively preventing peptide leakage.
[0019] Reference Figure 3 An expansion groove 204 is provided on the inner wall of the liquid inlet 108. A first spring 205 is fixedly connected inside the liquid inlet 108. An inclined block 206 is fixedly connected to the end of the first spring 205 away from the liquid inlet 108. A squeezing column 207 is fixedly connected to the top of the inclined block 206. A positioning frame 208 is attached to the bottom of the inclined block 206. A second spring 209 is fixedly connected to the inner wall of the positioning frame 208. A positioning plate 210 is fixedly connected to the end of the second spring 209 away from the positioning frame 208. The positioning plate 210 is connected to the liquid inlet... The inlet 108 is fixedly connected, and the inner wall of the inlet 108 is provided with a telescopic opening 211. By rotating the sealing plug 202, the sealing plug 202 squeezes the extrusion column 207, thereby squeezing the positioning frame 208 by the extrusion column 207 and the inclined block 206. The positioning frame 208 moves into the inlet 108 through the telescopic opening 211, thereby squeezing the sealing plug 202 and keeping the sealing plug 202 stable. This allows the sealing assembly 2 to better seal the tank 1, thereby preventing the leakage of peptides.
[0020] Working principle: By injecting the polypeptide into the storage tank 104, which is filled with nitrogen, and inserting the tank lid 201 and sealing plug 202 into the liquid inlet 108, the tank lid 201 compresses the extrusion column 207. This causes the extrusion column 207 and the inclined block 206 to compress the positioning frame 208, thereby moving the positioning frame 208 into the liquid inlet 108 through the telescopic port 211. This allows the positioning frame 208 to compress and fix the sealing plug 202, preventing... If the can lid 201 becomes loose, the sealing plug 202, after entering the inlet 108, will press and adhere to the sealing ring 212 and the sealing gasket 213, thereby effectively sealing the inside of the storage tank 104 and preventing oxygen from entering the storage tank 104. An insulation layer 103 is provided between the protective shell 101 and the storage tank 104, and the gas inside the isolation tank 102 is extracted, making the inside of the isolation tank 102 approach a vacuum state, which can effectively keep the peptides inside the storage tank 104 warm, thereby making the peptides more stable.
[0021] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. A liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure, comprising a tank body (1), characterized in that, The top of the tank (1) is provided with a sealing assembly (2). The tank (1) includes a protective shell (101), a heat insulation layer (103) and a storage tank (104). An isolation groove (102) is provided between the protective shell (101) and the storage tank (104). The side of the protective shell (101) close to the storage tank (104) is attached to the heat insulation layer (103). The top of the protective shell (101) is provided with a liquid inlet (108).
2. A liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure according to claim 1, characterized in that, The inner bottom of the protective shell (101) is fixedly connected to a support column (105), and a limiting ring (106) is fixedly connected to the side of the support column (105) near the storage container (104). The inner sidewall of the limiting ring (106) is in contact with the bottom of the storage container (104).
3. A liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure according to claim 1, characterized in that, The outer wall of the protective shell (101) is provided with an air extraction port (107), which is connected to the isolation groove (102). A flange is provided at the end of the air extraction port (107) away from the protective shell (101).
4. A liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure according to claim 1, characterized in that, The sealing assembly (2) includes a can cover (201) that fits against the outer wall of the liquid inlet (108). A sealing plug (202) is fixedly connected to the bottom center of the can cover (201). The outer wall of the sealing plug (202) is adapted to the inner wall of the liquid inlet (108). A threaded groove (203) is provided on the outer wall of the liquid inlet (108).
5. A liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure according to claim 4, characterized in that, The can lid (201) is threaded to the inlet (108) via a threaded groove (203), and the inner wall of the inlet (108) is fixedly connected with a sealing ring (212) and a sealing gasket (213).
6. A liquid polypeptide storage tank with a leak-proof and polypeptide stability protection structure according to claim 1, characterized in that, The inner wall of the liquid inlet (108) is provided with a telescopic groove (204). A first spring (205) is fixedly connected inside the liquid inlet (108). A wedge block (206) is fixedly connected to the end of the first spring (205) away from the liquid inlet (108). A squeezing column (207) is fixedly connected to the top of the wedge block (206). A positioning frame (208) is attached to the bottom of the wedge block (206). A second spring (209) is fixedly connected to the inner wall of the positioning frame (208). A positioning plate (210) is fixedly connected to the end of the second spring (209) away from the positioning frame (208). The positioning plate (210) is fixedly connected to the liquid inlet (108). A telescopic opening (211) is provided on the inner wall of the liquid inlet (108).