A level control device, an electrophoresis device and a western blot analyzer

Abstract

The utility model relates to protein analysis technical field, the utility model discloses a horizontal control device, electrophoresis device and protein immunoblotting analysis appearance, the horizontal control device includes horizontal moving device and horizontal correction device, horizontal moving device includes bottom plate, horizontal drive motor, drive shaft, first guide rail and second guide rail, horizontal drive motor, first guide rail and second guide rail all install on the bottom plate, and the output shaft of horizontal drive motor is connected drive shaft, horizontal correction device is located on the bottom plate, and both sides are slidably connected first guide rail and second guide rail, and horizontal correction device screw connection drive shaft, can carry out linear motion along first guide rail and second guide rail under the driving of drive shaft. The utility model can realize accurate horizontal adjustment and position movement control.

Description

Technical Field

[0001] This utility model relates to the field of protein analysis technology, and in particular to a level control device, an electrophoresis device, and a protein immunoblotting analyzer. Background Technology

[0002] During electrophoresis, the horizontal state of the apparatus is crucial to the experimental results. An uneven electric field distribution and inconsistent sample migration rates will affect the separation effect and data accuracy.

[0003] Most existing electrophoresis apparatuses are fixed structures, making them difficult to move flexibly according to experimental needs. At the same time, laboratory benchtops are often uneven, and traditional apparatuses lack effective leveling mechanisms, usually relying on manual methods using shims or adjustable feet to maintain levelness, which results in low adjustment accuracy and cumbersome operation.

[0004] Therefore, there is an urgent need to propose a horizontal control device, an electrophoresis device, and a protein immunoblotting analyzer to solve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a horizontal control device, an electrophoresis device, and a protein immunoblotting analyzer that can achieve precise horizontal adjustment and position movement control.

[0006] To solve the above-mentioned technical problems, this utility model provides a horizontal control device, including a horizontal moving device and a horizontal correction device; the horizontal moving device includes a base plate, a horizontal drive motor, a drive shaft, a first guide rail, and a second guide rail; the horizontal drive motor, the first guide rail, and the second guide rail are all mounted on the base plate, and the output shaft of the horizontal drive motor is connected to the drive shaft; the horizontal correction device is located on the base plate, and the first guide rail and the second guide rail are slidably connected to its two sides respectively, and the horizontal correction device is threadedly connected to the drive shaft, and can move linearly along the first guide rail and the second guide rail under the drive of the drive shaft.

[0007] Furthermore, the horizontal moving device also includes a mounting bracket; the mounting bracket is mounted on the base plate, the horizontal drive motor is mounted on the mounting bracket, and the output shaft passes through the mounting bracket and is connected to the drive shaft.

[0008] Furthermore, the horizontal movement device also includes a position detection switch; the position detection switch is mounted on the mounting bracket and is used to detect the position of the horizontal correction device.

[0009] Furthermore, the drive shaft includes a threaded shaft, and the leveling device is provided with a nut that mates with the threaded shaft. The drive motor drives the nut to move by rotating the threaded shaft, thereby pushing the leveling device to move along the first guide rail and the second guide rail.

[0010] Furthermore, the first guide rail and the second guide rail are arranged in parallel; the horizontal correction device has sliders on both sides that cooperate with the first guide rail and the second guide rail, and the sliders are slidably connected to the first guide rail and the second guide rail.

[0011] Furthermore, the leveling device includes: a base, two power components and a balancing component, wherein the two power components and the balancing component are mounted on the base, and the balancing component and the two power components are not on the same straight line.

[0012] Furthermore, the balancing member is configured as a rod extending along a first direction and vertically mounted on the base, and the power member includes a moving part that moves along the first direction.

[0013] Furthermore, the balancing component is configured as a power component, and three power components are mounted on the base. Each power component includes a moving part that moves along a first direction.

[0014] Furthermore, this utility model also proposes an electrophoresis device, including the horizontal control device as described above, and further including a device body and a temperature control mechanism; the device body is provided with a connecting part, which is located at the circumferential edge of the device body; the temperature control mechanism is mounted on the device body; the horizontal correction device of the horizontal control device is connected to the connecting part, and both the device body and the temperature control mechanism are located on the horizontal correction device; the horizontal control device is used to drive the device body to move in a straight line and to adjust the horizontal angle of the device body so that the device body remains horizontal.

[0015] In addition, this invention also proposes a protein immunoblotting analyzer, including the electrophoresis device as described above.

[0016] Through the above technical solution, this utility model has the following beneficial effects:

[0017] By incorporating a horizontal movement device and a horizontal correction device, the position movement control and horizontal adjustment functions of the electrophoresis apparatus are organically combined. The horizontal movement device adopts a combination structure of a base plate, a horizontal drive motor, a drive shaft, and a guide rail, enabling the horizontal correction device to perform stable and precise linear motion along the guide rail under the drive shaft, thus solving the problems of fixed position and inconvenient movement of traditional electrophoresis apparatuses.

[0018] In addition, the horizontal correction device in this apparatus can adjust the horizontal angle of the electrophoresis apparatus body placed on it, so that the apparatus remains horizontal during electrophoresis, thereby improving the electrophoretic separation effect and the accuracy of experimental data. Attached Figure Description

[0019] Figure 1 This is a three-dimensional structural diagram of the horizontal control device in one embodiment of the present invention;

[0020] Figure 2 This is a side view of the horizontal control device in one embodiment of the present invention;

[0021] Figure 3 This is an exploded view of the electrophoresis device in the horizontal control device according to an embodiment of the present invention;

[0022] Figure 4 This is a schematic diagram of the structure of the horizontal moving device in the horizontal control device according to one embodiment of the present invention.

[0023] In the diagram, 20 is the horizontal moving device; 21 is the horizontal correction device; 22 is the base plate; 23 is the horizontal drive motor; 24 is the drive shaft; 25 is the first guide rail; 26 is the second guide rail; 27 is the mounting bracket; 28 is the position detection switch; and 29 is the nut. Detailed Implementation

[0024] Based on the teachings of this specification, those skilled in the art can form new technical solutions through cross-combination of different implementation methods without creating technical contradictions. Such variations should all be considered to fall within the protection scope of this utility model.

[0025] The following description, in conjunction with the accompanying drawings, provides a more detailed account of a horizontal control device, an electrophoresis apparatus, and a protein immunoblotting analyzer according to the present invention. Preferred embodiments of the present invention are shown. It should be understood that those skilled in the art can modify the present invention described herein while still achieving its advantageous effects. Therefore, the following description should be understood as being of general knowledge to those skilled in the art and is not intended to limit the present invention.

[0026] The present invention will be described in more detail below by way of example with reference to the accompanying drawings. The advantages and features of the present invention will become clearer from the following description. It should be noted that the drawings are in a very simplified form and use non-precise proportions, and are only used to facilitate and clarify the illustration of the embodiments of the present invention.

[0027] like Figures 1-4As shown in the figure, this utility model embodiment proposes a horizontal control device, including a horizontal moving device 20 and a horizontal correction device 21. Specifically, the horizontal moving device 20 includes a base plate 22, a horizontal drive motor 23, a drive shaft 24, a first guide rail 25, and a second guide rail 26; the horizontal drive motor 23, the first guide rail 25, and the second guide rail 26 are all mounted on the base plate 22, and the output shaft of the horizontal drive motor 23 is connected to the drive shaft 24; the horizontal correction device 21 is located on the base plate 22, and the first guide rail 25 and the second guide rail 26 are slidably connected to its two sides respectively, and the horizontal correction device 21 is threadedly connected to the drive shaft 24, and can move linearly along the first guide rail 25 and the second guide rail 26 under the drive of the drive shaft 24. This embodiment enables the horizontal correction device 21 to perform stable and precise linear movement under the drive of the drive shaft 24, improving the movement control accuracy and flexibility of the electrophoresis device, and solving the problem of fixed position and inconvenient movement of traditional electrophoresis devices.

[0028] Preferably, the horizontal moving device 20 further includes a mounting bracket 27. The mounting bracket 27 is mounted on the base plate 22, the horizontal drive motor 23 is mounted on the mounting bracket 27, and the output shaft passes through the mounting bracket 27 and is connected to the drive shaft 24. The mounting bracket 27 enhances the stability of the connection between the horizontal drive motor 23 and the drive shaft 24, while providing additional installation space to facilitate the arrangement and installation of other components.

[0029] In one embodiment, the horizontal movement device 20 further includes a position detection switch 28. Specifically, the position detection switch 28 is mounted on the mounting bracket 27 and is used to detect the position of the horizontal correction device 21. In a specific example, the position detection switch 28 can be a proximity switch, photoelectric switch, or Hall effect switch, etc. The position detection switch 28 is electrically connected to the control system. When the horizontal correction device 21 moves to a preset position, the position detection switch 28 is triggered and sends a signal to the control system. After receiving the signal, the control system controls the horizontal drive motor 23 to decelerate or stop according to a preset program, thereby achieving precise positioning of the horizontal correction device 21. In this embodiment, multiple position detection switches 28 can be set at different positions to detect the starting position, ending position, and intermediate key positions of the horizontal correction device 21, improving the flexibility and accuracy of position control. This automated position control method can avoid the inaccuracies of manual control, improve the repeatability and safety of system operation, and avoid equipment damage caused by improper position control.

[0030] In this embodiment, the automated control principle of the leveling device is as follows: The control system receives signals from a level sensor, which can be an electronic level or an inclinometer, installed on the main body of the device to monitor its levelness in real time. When the device body is detected to be deviating from its level, the control system calculates the angle and direction that need to be adjusted, and then controls the moving parts of the three power components on the leveling device 21 to extend and retract to the appropriate positions, thereby adjusting the leveling angle of the main body. The entire process is completed automatically by the control system without manual intervention, improving the accuracy and response speed of leveling adjustment. Simultaneously, the control system also precisely controls the start, stop, and speed of the leveling drive motor 23 based on the feedback signal from the position detection switch 28, achieving precise positioning of the leveling device 21. This closed-loop control method improves the automation level and safety of the system, avoiding equipment damage caused by improper position control.

[0031] In this embodiment, the drive shaft 24 includes a threaded shaft, and the horizontal correction device 21 is provided with a nut 29 that mates with the threaded shaft. The drive motor rotates the threaded shaft to drive the nut 29, thereby pushing the horizontal correction device 21 to move along the first guide rail 25 and the second guide rail 26. The mating structure of the threaded shaft and the nut 29 converts rotational motion into linear motion, improving transmission efficiency and positioning accuracy, while also having good self-locking performance, enhancing the stability of the system in a static state.

[0032] This embodiment also includes a nut 29 mounting bracket, which is fixed on the horizontal correction device 21, and the nut 29 is installed in the nut 29 mounting bracket.

[0033] Preferably, the first guide rail 25 and the second guide rail 26 are arranged in parallel; the horizontal correction device 21 has sliders on both sides that cooperate with the first guide rail 25 and the second guide rail 26, and the sliders are slidably connected to the first guide rail 25 and the second guide rail 26. In a specific example, the first guide rail 25 and the second guide rail 26 can be standard linear guide rails, and the sliders can be linear guide rail sliders with ball bearings or sliders. This structure of parallel arrangement of the two guide rails can enhance the stability and accuracy of the movement of the horizontal correction device 21, prevent swaying and deviation during the movement, and thus improve the operational reliability of the overall system.

[0034] In one embodiment, the leveling device 21 includes: a base, two power components and a balancing component, wherein the two power components and the balancing component are mounted on the base, and the balancing component and the two power components are not on the same straight line.

[0035] In this embodiment, the balancing member is configured as a rod extending along a first direction and vertically mounted on the base, and the power member includes a moving part that moves along the first direction.

[0036] Preferably, the balancing component is configured as a power component, and three power components are mounted on the base. Each power component includes a moving part that moves along a first direction.

[0037] Furthermore, this embodiment also proposes an electrophoresis apparatus, including the horizontal control device as described above, and further including an apparatus body and a temperature control mechanism; the apparatus body is provided with a connecting part, which is located at the circumferential edge of the apparatus body; the temperature control mechanism is mounted on the apparatus body; the horizontal correction device 21 of the horizontal control device is connected to the connecting part, and both the apparatus body and the temperature control mechanism are located on the horizontal correction device 21; the horizontal control device is used to drive the apparatus body to move in a straight line and to adjust the horizontal angle of the apparatus body so that the apparatus body remains horizontal.

[0038] The specific structure of the constant temperature mechanism, the horizontal correction device 21, and the main body of the device in this embodiment can be referred to as "A Constant Temperature Horizontal Electrophoresis Device" in publication number CN119688808A, specifically the "constant temperature mechanism," "horizontal mechanism," and "main body of the device." For example, the correction process of the horizontal correction device 21 refers to the correction process of the "horizontal mechanism."

[0039] In addition, this embodiment also proposes a protein immunoblotting analyzer, including the electrophoresis device as described above.

[0040] In this embodiment, the horizontal drive motor 23 drives the drive shaft 24 to rotate via its output shaft. The thread on the drive shaft 24 engages with the nut 29 on the horizontal correction device 21, converting the rotational motion into linear motion and propelling the horizontal correction device 21 to move linearly along the first guide rail 25 and the second guide rail 26. During the movement, the position detection switch 28 monitors the position information of the horizontal correction device 21 in real time. When it reaches a preset position, it controls the horizontal drive motor 23 to stop or adjust its speed. Simultaneously, the power component on the horizontal correction device 21 adjusts the support height through the telescopic movement of the moving part, working together with the balancing component to achieve the horizontal angle adjustment of the electrophoresis device body. Those skilled in the art will understand that parameters such as the telescopic stroke of the power component, the speed of the horizontal drive motor 23, and the trigger position of the position detection switch 28 can be set according to actual needs, and the above implementation also includes other embodiments besides this one.

[0041] In summary, the horizontal control device, electrophoresis device, and protein immunoblotting analyzer proposed in this utility model have the following advantages:

[0042] By incorporating a horizontal movement device and a horizontal correction device, the position movement control and horizontal adjustment functions of the electrophoresis apparatus are organically combined. The horizontal movement device adopts a combination structure of a base plate, a horizontal drive motor, a drive shaft, and a guide rail, enabling the horizontal correction device to perform stable and precise linear motion along the guide rail under the drive shaft, thus solving the problems of fixed position and inconvenient movement of traditional electrophoresis apparatuses.

[0043] In addition, the horizontal correction device in this apparatus can adjust the horizontal angle of the electrophoresis apparatus body placed on it, so that the apparatus remains horizontal during electrophoresis, thereby improving the electrophoretic separation effect and the accuracy of experimental data.

[0044] Obviously, those skilled in the art can make various modifications and variations to this utility model without departing from its spirit and scope. Therefore, if these modifications and variations fall within the scope of the claims of this utility model and their equivalents, this utility model also intends to include these modifications and variations.

Claims

1. A horizontal control device, characterized in that, The device includes a horizontal moving device and a horizontal correction device. The horizontal moving device includes a base plate, a horizontal drive motor, a drive shaft, a first guide rail, and a second guide rail. The horizontal drive motor, the first guide rail, and the second guide rail are all mounted on the base plate, and the output shaft of the horizontal drive motor is connected to the drive shaft. The horizontal correction device is located on the base plate and is slidably connected to the first guide rail and the second guide rail on both sides. The horizontal correction device is threadedly connected to the drive shaft and can move linearly along the first guide rail and the second guide rail under the drive of the drive shaft.

2. The horizontal control device as described in claim 1, characterized in that, The horizontal moving device further includes a mounting bracket; the mounting bracket is mounted on the base plate, the horizontal drive motor is mounted on the mounting bracket, and the output shaft passes through the mounting bracket and is connected to the drive shaft.

3. The horizontal control device as described in claim 2, characterized in that, The horizontal movement device also includes a position detection switch; the position detection switch is mounted on the mounting bracket and is used to detect the position of the horizontal correction device.

4. The horizontal control device as described in claim 1, characterized in that, The drive shaft includes a threaded shaft, and the leveling device is provided with a nut that mates with the threaded shaft. The drive motor drives the nut to move by rotating the threaded shaft, thereby pushing the leveling device to move along the first guide rail and the second guide rail.

5. The horizontal control device as described in claim 1, characterized in that, The first guide rail and the second guide rail are arranged in parallel; the horizontal correction device has sliders on both sides that cooperate with the first guide rail and the second guide rail, and the sliders are slidably connected to the first guide rail and the second guide rail.

6. The horizontal control device as described in claim 1, characterized in that, The horizontal correction device includes: a base, two power components and a balancing component, wherein the two power components and the balancing component are mounted on the base, and the balancing component and the two power components are not on the same straight line.

7. The horizontal control device as described in claim 6, characterized in that, The balancing component is configured as a rod extending along a first direction and vertically mounted on the base, and the power component includes a moving part that moves along the first direction.

8. The horizontal control device as described in claim 6, characterized in that, The balancing component is configured as a power component, and three power components are mounted on the base. Each power component includes a moving part that moves along a first direction.

9. An electrophoresis apparatus, comprising a level control device as described in any one of claims 1-8, characterized in that, It also includes a device body and a temperature control mechanism; the device body is provided with a connecting part, which is located at the circumferential edge of the device body; the temperature control mechanism is installed on the device body; the level correction device of the level control device is connected to the connecting part, and both the device body and the temperature control mechanism are located on the level correction device; the level control device is used to drive the device body to move in a straight line and to adjust the horizontal angle of the device body so that the device body remains horizontal.

10. A protein immunoblotting analyzer, characterized in that, Includes the electrophoresis apparatus as described in claim 9.

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