High safety type high performance liquid chromatograph preventing liquid storage bottle from pouring

Abstract

The application relates to the technical field of liquid chromatographs, in particular to a high-safety high-performance liquid chromatograph capable of preventing a solvent bottle from being poured, which comprises a column box, a sample inlet part arranged on one side of the column box, a detection part arranged at the top end of the sample inlet part and a solvent box arranged at the top end of the column box, a stabilizing part arranged at the top end of the solvent box and a vibrating part arranged at the top end of the column box. The application is characterized in that the cooperation between the pull rod and the air inlet pipe enables the gas to enter the filling ball in one direction, the filling ball collides with the space between the filling stabilizing frame and the solvent bottle, the solvent bottle is filled and protected, the effect of preventing the solvent bottle from being poured and stabilizing the connection between the solvent bottle and the hose is achieved, the cooperation between the vibrating spring and the long rod enables the vibration condition of the equipment to be observed through the pointer and the angle line, and the effect that the device can accurately observe and judge whether the equipment is abnormally vibrated is achieved.

Description

Technical Field

[0001] This application relates to the field of liquid chromatography technology, and in particular to a high-safety high-performance liquid chromatograph that prevents the liquid storage bottle from tipping over. Background Technology

[0002] High-performance liquid chromatography (HPLC) is an instrument that separates, analyzes, and identifies mixtures by utilizing the difference in the partition ratio between the liquid and solid phases or between two immiscible liquids. It has a wide range of applications in the fields of biology and chemistry. HPLC is one of the fastest-growing analytical instruments in the world and is widely used in the analysis of various liquid samples, especially in the fields of pharmaceuticals, biochemistry, petrochemicals, environmental sanitation, and food. HPLC can analyze 70%-80% of the total number of organic chemicals and can be applied to product quality analysis in various industries.

[0003] A liquid chromatograph includes a pump, an injection system, a temperature control system, a column, a detector, and a signal recording system. The injection system is located at the top of the liquid chromatograph and includes a reservoir bottle. The reservoir bottle is connected to other instruments via a hose. Vibration is unavoidable during the use of existing liquid chromatographs, and the solvent bottle will also shake. When the amplitude is large, it will affect the sealing of the connection between the solvent bottle and the hose, causing the reservoir bottle to tip over or the liquid in the reservoir bottle to leak out during the delivery process. Existing equipment lacks the effect of preventing the reservoir bottle from tipping over and stabilizing the connection between the reservoir bottle and the hose. Utility Model Content

[0004] To address the problems mentioned in the background section, this application provides a high-safety high-performance liquid chromatograph that prevents the liquid storage bottle from tipping over.

[0005] This application provides a high-safety high-performance liquid chromatograph that prevents liquid storage bottles from tipping over, employing the following technical solution: A high-safety high-performance liquid chromatograph that prevents liquid storage bottles from tipping over includes a column oven, an injection unit disposed on one side of the column oven, a detection unit disposed at the top of the injection unit, and a solvent cartridge disposed at the top of the column oven.

[0006] The stabilizing component is located at the top of the solvent cartridge, including a filling protection structure and an air intake structure located at the top of the solvent cartridge.

[0007] The vibrating element is located at the top of the column box, including a vibration amplification structure located at the top of the column box and an observation structure located at the top of the vibrating element.

[0008] Optionally, there are multiple stabilizing components, and the filling protection structure of each stabilizing component includes a stabilizing frame. Each stabilizing frame has a filling ball on its inner sidewall. Each filling ball is made of elastic polyurethane. Each stabilizing frame has a through-hole on its outer sidewall. Each vent is located inside the stabilizing frame and connected to the inside of the filling ball. Each stabilizing frame has a solvent bottle inside, and the bottom of each solvent bottle is located inside a solvent box.

[0009] Optionally, the air intake structure of each of the stabilizers includes an air intake pipe, each air intake pipe is disposed on the outer wall of the stabilizer frame, each air intake pipe is provided with a pull rod inside, each pull rod is provided with an air intake port through one end of the air intake pipe, each air intake port is funnel-shaped, the bottom of the air intake port is larger, each air intake port is provided with a blocking spring at the bottom, each blocking spring is provided with a blocking ball at the top, and the size of each blocking ball is adapted to the size of the top of the air intake port.

[0010] Optionally, the vibration amplification structure of the vibrating element includes a long rod, which is disposed at the top of the column box, and a dial is disposed at the top of the long rod. The dial is made of a transparent material and is shaped like a hollow fan.

[0011] Optionally, the observation structure of the vibrating element includes a vibration spring, the bottom end of which is fixedly disposed inside the bottom of the dial, a pointer is disposed at the top end of the vibration spring, and an angle line is disposed on the inner sidewall of the dial.

[0012] Optionally, the column oven includes a temperature control system and a chromatographic column, and the detection element includes a display, a detector, and control keys.

[0013] Optionally, the injection device includes an infusion pump, an injection column, a sampling tube, and an injection port, wherein the sampling tube inside the injection device is connected to a solvent bottle.

[0014] In summary, this application includes the following beneficial technical effects:

[0015] 1. This utility model, through the setting of a stabilizing component, prevents the blocking ball from pressing against the top of the air inlet when the spring naturally extends, so that gas can only enter the air inlet pipe from the external environment in one direction. When the pull rod moves away from the air inlet pipe, the gas enters the air inlet pipe. When the pull rod enters the air inlet pipe, the gas enters the filling ball. Reciprocatingly pulling the pull rod causes the gas in the filling ball to continuously increase, causing its volume to expand and fill the space between the stabilizing component and the solvent bottle. This prevents the liquid storage bottle from tipping over and stabilizes the connection between the solvent bottle and the hose. Opening the air outlet switch can release the gas in the filling ball, allowing the solvent bottle to be removed and replaced normally.

[0016] 2. This utility model, through the setting of a vibrating component and the cooperation between the vibrating spring and the long rod, causes the equipment to vibrate continuously during operation. The vibration is transmitted to the long rod, which amplifies the vibration and transmits it to the vibrating spring. One side of the pointer swings continuously with the vibration of the spring. The amplitude and angle of the pointer swing can be observed through the angle line in the dial, thereby knowing the vibration amplitude of the equipment. The reading can be used to judge whether the equipment is malfunctioning, making the judgment more accurate. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure in an embodiment of this application;

[0018] Figure 2 This is a schematic diagram of the solvent cartridge structure in an embodiment of this application;

[0019] Figure 3 This is a schematic diagram of the internal structure of the intake pipe in an embodiment of this application;

[0020] Figure 4 This is a schematic diagram of the vibration element structure in the embodiments of this application;

[0021] Figure 5 This is a schematic diagram of the internal structure of the dial in an embodiment of this application.

[0022] Figure reference numerals: 1. Column oven; 2. Solvent box; 3. Stabilizer; 301. Stabilizer frame; 302. Gas outlet; 303. Solvent bottle; 304. Filler ball; 305. Pull rod; 306. Gas inlet tube; 307. Gas inlet; 308. Blocking ball; 309. Blocking spring; 4. Vibration element; 401. Long rod; 402. Dial; 403. Vibration spring; 404. Angle line; 405. Pointer; 5. Detection element; 6. Injection element. Detailed Implementation

[0023] The following is in conjunction with the appendix Figure 1-4 This application will be described in further detail.

[0024] This application discloses a high-safety high-performance liquid chromatograph that prevents the liquid storage bottle from tipping over. For example... Figure 1 As shown, the system includes a column oven 1, an injection unit 6 located on one side of the column oven 1, a detection unit 5 located at the top of the injection unit 6, and a solvent cartridge 2 located at the top of the column oven 1. The column oven 1 includes a temperature control system and a chromatographic column. The detection unit 5 includes a display, a detector, and control keys. The injection unit 6 includes an infusion pump, an injection column, a sampling tube, and an injection port. The sampling tube inside the injection unit 6 is connected to a solvent bottle 303. The solution to be separated and detected in the solvent bottle 303 is introduced into the detection system through the injection unit 6 via a flexible tube, so that both the liquid phase and the solution are introduced into the column oven 1. Under the separation action of the chromatographic column, the substances are separated. The detection unit 5 is used to convert the chemical signal into an electrical signal for the user to observe the detection results.

[0025] Please see Figure 2 The stabilizing component 3 is located at the top of the solvent container 2, and the filling protection structure is located at the top of the solvent container 2. There are multiple stabilizing components 3. Each stabilizing component 3 has a stabilizing frame 301. Each stabilizing frame 301 has a filling ball 304 on its inner side wall. Each filling ball 304 is made of elastic polyurethane. Gas is introduced into the filling ball 304 to expand its volume and fill the space between the stabilizing component 3 and the solvent bottle 303. This prevents the liquid storage bottle from tipping over and stabilizes the connection between the solvent bottle 303 and the hose. The solvent bottle 303 is used to store various liquid phases.

[0026] Please see Figure 2 Each stabilizing frame 301 has an air outlet 302 through its outer wall. Each air outlet 302 is located inside the stabilizing frame 301 and connected to the inside of the filling ball 304. Each stabilizing frame 301 has a solvent bottle 303 inside it. The bottom of each solvent bottle 303 is located inside the solvent box 2. Opening the air outlet 302 can release the gas inside the filling ball 304 and allow the solvent bottle 303 to be removed and replaced normally.

[0027] Please see Figure 3 The air intake structure is located at the top of the solvent box 2. The inflation structure of each stabilizing component 3 includes an air intake pipe 306. Each air intake pipe 306 is located on the outer wall of the stabilizing frame 301. Each air intake pipe 306 has a pull rod 305 inside. Each pull rod 305 has an air inlet 307 extending through one end of the air intake pipe 306. Each air inlet 307 is funnel-shaped with a larger bottom end. Each air inlet 307 has a blocking spring 3 at its bottom end. 09. Each blocking spring 309 has a blocking ball 308 at its top. The size of each blocking ball 308 is adapted to the size of the top of the air inlet 307. When the blocking spring 309 is naturally extended, the blocking ball 308 presses against the top of the air inlet 307. Gas can only enter the air inlet pipe 306 from the external environment in one direction. The lever 305 moves away from the air inlet pipe 306, and the gas enters the air inlet pipe 306. The lever 305 enters the air inlet pipe 306, and the gas enters the filling ball 304.

[0028] Please see Figure 4 The vibrating element 4 is located at the top of the column box 1, and the vibration amplification structure is located at the top of the column box 1. The vibration amplification structure of the vibrating element 4 includes a long rod 401, which is located at the top of the column box 1. A dial 402 is located at the top of the long rod 401. The dial 402 is made of transparent material and is shaped like a hollow fan. The long rod 401 can amplify the vibration generated when the equipment is working.

[0029] Please see Figure 5The observation structure is located at the top of the vibrating element 4. The observation structure of the vibrating element 4 includes a vibration spring 403. The bottom end of the vibration spring 403 is fixedly located inside the bottom of the dial 402. A pointer 405 is located at the top of the vibration spring 403. An angle line 404 is located on the inner side wall of the dial 402. The pointer 405 swings continuously with the vibration of the vibration spring 403. The amplitude and angle of the swing of the pointer 405 can be observed through the angle line 404 inside the dial 402, thereby knowing the vibration amplitude of the equipment. The reading can be used to determine whether the equipment is malfunctioning, making the judgment more accurate.

[0030] The implementation principle of a high-safety high-performance liquid chromatograph for preventing liquid storage bottle tipping in this application embodiment is as follows: When the blocking spring 309 is naturally extended, the blocking ball 308 presses against the top of the air inlet 307, allowing gas to enter the air inlet pipe 306 from the external environment in only one direction. The pull rod 305 moves away from the air inlet pipe 306, allowing gas to enter the air inlet pipe 306. The pull rod 305 then enters the air inlet pipe 306, and the gas enters the filling ball 304. Reciprocating pulling pushes the pull rod 305, causing the filling ball 304 to continuously increase in gas, thus expanding its volume and filling the space between the stabilizing member 3 and the solvent bottle 303, preventing the liquid storage bottle from tipping over. The solvent bottle 303 is connected to the hose. Opening the vent 302 releases the gas from the filling ball 304. The solvent bottle 303 can then be removed and replaced normally. The equipment vibrates continuously during operation, and the vibration is transmitted to the long rod 401. The long rod 401 amplifies the vibration and transmits it to the vibration spring 403. The pointer 405 swings continuously with the vibration of the vibration spring 403. The amplitude and angle of the pointer 405 swing can be observed through the angle line 404 in the dial 402, thus indicating the vibration amplitude of the equipment. The reading is used to determine whether the equipment is malfunctioning, making the judgment more accurate.

[0031] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A high-safety high-performance liquid chromatograph that prevents the storage bottle from tipping over, comprising a column oven (1), an injection unit (6) disposed on one side of the column oven (1), a detection unit (5) disposed at the top of the injection unit (6), and a solvent cartridge (2) disposed at the top of the column oven (1), characterized in that: The stabilizing component (3) is disposed at the top of the solvent box (2), including a filling protection structure disposed at the top of the solvent box (2) and an air intake structure disposed at the top of the solvent box (2); The vibrating element (4) is located at the top of the column box (1), including a vibration amplification structure located at the top of the column box (1) and an observation structure located at the top of the vibrating element (4).

2. The high-safety high-performance liquid chromatograph for preventing liquid storage bottles from tipping over, as described in claim 1, is characterized in that: The number of the stabilizing components (3) is multiple. The filling protection structure of each stabilizing component (3) includes a stabilizing frame (301). Each stabilizing frame (301) has a filling ball (304) on its inner side wall. Each filling ball (304) is made of elastic polyurethane. Each stabilizing frame (301) has an air outlet (302) through its outer side wall. Each air outlet (302) is located inside the stabilizing frame (301) and connected to the inside of the filling ball (304). Each stabilizing frame (301) has a solvent bottle (303) inside it. The bottom of each solvent bottle (303) is located inside the solvent box (2).

3. The high-safety high-performance liquid chromatograph for preventing liquid storage bottles from tipping over as described in claim 1, characterized in that: Each of the stabilizers (3) includes an air intake pipe (306) in its air intake structure. Each air intake pipe (306) is located on the outer wall of the stabilizer frame (301). Each air intake pipe (306) has a pull rod (305) inside it. Each pull rod (305) has an air inlet (307) through it at one end of the air intake pipe (306). Each air inlet (307) is funnel-shaped. The bottom of the air inlet (307) is larger. Each air inlet (307) has a blocking spring (309) at its bottom. Each blocking spring (309) has a blocking ball (308) at its top. The size of each blocking ball (308) is adapted to the size of the top of the air inlet (307).

4. A high-safety high-performance liquid chromatograph for preventing liquid storage bottles from tipping over, as described in claim 1, is characterized in that: The vibration amplification structure of the vibrating element (4) includes a long rod (401), which is located at the top of the column box (1). A dial (402) is located at the top of the long rod (401). The dial (402) is made of transparent material and is shaped as a hollow fan.

5. A high-safety high-performance liquid chromatograph for preventing liquid storage bottles from tipping over, as described in claim 1, characterized in that: The observation structure of the vibrating element (4) includes a vibration spring (403), the bottom end of which is fixedly disposed inside the bottom end of the dial (402), a pointer (405) is disposed at the top end of the vibration spring (403), and an angle line (404) is disposed on the inner side wall of the dial (402).

6. A high-safety high-performance liquid chromatograph for preventing liquid storage bottles from tipping over, as described in claim 1, is characterized in that: The column oven (1) includes a temperature control system and a chromatographic column, and the detection element (5) includes a display, a detector and control keys.

7. A high-safety high-performance liquid chromatograph for preventing liquid storage bottles from tipping over, as described in claim 1, characterized in that: The injection unit (6) includes an infusion pump, an injection column, a sampling tube and an injection port. The sampling tube inside the injection unit (6) is connected to the solvent bottle (303).

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