A gastric lavage fluid screening gastric cancer sampling device

Abstract

The utility model relates to medium conveying technical field, concretely relates to a sampling device for screening gastric cancer with gastric lavage fluid, including catheter and three -way valve, the catheter includes coaxially nested setting inner tube and outer tube, the outer tube can slide along the inner tube axial, the front end of inner tube is along tangential and is opened to have lateral hole, the outer tube covers the lateral hole completely under initial state, the rear end of inner tube is provided with limit component, and the lateral hole is exposed when the outer tube retracts when driving limit component. Compared with the traditional method, the technical scheme of the utility model has three core designs of pollution prevention structure, structure optimization and functional innovation, solves the problems of pollution, low efficiency and complex operation of the traditional gastric lavage fluid sampling device, significantly improves the accuracy of gastric cancer screening and patient comfort, and has high clinical application value.

Description

Technical Field

[0001] This utility model relates to the field of media delivery technology, specifically to a sampling device for gastric lavage fluid screening for gastric cancer. Background Technology

[0002] Gastric cancer is a malignant tumor originating from the gastric mucosal epithelium. It can occur in any part of the stomach, with more than half occurring in the antrum. The greater curvature, lesser curvature, and anterior and posterior walls of the stomach can also be affected. The vast majority of gastric cancers are adenocarcinomas, which often present with no obvious symptoms in the early stages, or with nonspecific symptoms such as upper abdominal discomfort and belching. These symptoms are often similar to those of chronic gastric diseases such as gastritis and gastric ulcers, making them easily overlooked. Early detection of gastric cancer involves using a gastric lavage device to infuse the patient's stomach with a cleaning solution, and then extracting the lavage fluid containing exfoliated cells from the gastric mucosal tissue for examination and screening.

[0003] Existing gastric lavage fluid sampling devices suffer from contaminants entering the sample during catheter insertion due to the outer wall contacting the oral / esophageal mucosa, affecting detection accuracy. When traditional catheters are inserted orally into the stomach, their outer wall becomes contaminated with saliva, oral bacteria, or esophageal exfoliated cells. These contaminants may flow back into the sample with the lavage fluid, interfering with the detection of gastric cancer markers (such as ctDNA and exosomes), leading to false positive or false negative results. Utility Model Content

[0004] This invention aims to at least partially solve one of the technical problems in related technologies. Therefore, the purpose of this invention is to provide a sampling device for gastric lavage fluid screening for gastric cancer, thereby improving detection accuracy.

[0005] The objective of this utility model can be achieved through the following technical solutions:

[0006] A sampling device for screening gastric cancer using gastric lavage fluid includes a catheter and a three-way valve. The catheter includes an inner tube and an outer tube that are coaxially nested, and the outer tube can slide along the axial direction of the inner tube.

[0007] The inner tube has a side hole that extends radially through its front end, and the outer tube completely covers the side hole in its initial state. The rear end of the inner tube is provided with a limiting component, and when the limiting component is driven, the outer tube retracts to expose the side hole.

[0008] The tail end of the inner tube is connected to the irrigation fluid injection channel and the negative pressure suction channel respectively through the three-way valve. The negative pressure suction channel is connected in series with the negative pressure suction device and the collection bottle.

[0009] In some embodiments of this utility model, a spring ring is sleeved on the inner wall of the front end of the inner tube.

[0010] In some embodiments of this utility model, the outer wall of the inner tube is provided with two axial guide strips, and the inner wall of the outer tube is provided with a corresponding guide groove to restrict the relative sliding direction.

[0011] In some embodiments of this utility model, the limiting component includes a limiting ring rotatably sleeved on the surface of the inner tube and a sliding groove penetrating the surface of the outer tube. The surface of the limiting ring is provided with a limiting block in the radial direction. The diameter of the limiting ring is the same as the diameter of the inner tube. The sliding groove is opened along the axial direction of the outer tube. A limiting groove is also circumferentially opened at the end of the sliding groove away from the limiting ring.

[0012] In some embodiments of this utility model, the front end of the inner tube is sequentially connected to a sealing cover and a filter screen, and the side hole is located between the two.

[0013] In some embodiments of this utility model, the sealing cover is made of medical-grade silicone material, and its front end is conical.

[0014] In some embodiments of this invention, 4-6 side holes are evenly distributed along the circumference of the inner tube, and the opening area of ​​a single side hole is 1-2 mm. 2 Furthermore, the edges of the side holes are rounded.

[0015] In some embodiments of this utility model, the outer tube surface is coated with a hydrophilic coating with a thickness of 5-10 μm and a friction coefficient ≤0.15.

[0016] In some embodiments of this utility model, a ceramic filter element and a duckbill-shaped one-way valve are connected in series at the inlet of the negative pressure suction channel. The pore size of the ceramic filter element is 0.5μm, and the opening pressure of the one-way valve is -50 to -80mmHg.

[0017] The technical solution of this utility model has at least the following advantages and beneficial effects:

[0018] Compared to traditional methods, this technical solution, through three core designs—anti-pollution structure, structural optimization, and functional innovation—solves the problems of pollution, low efficiency, and complex operation of traditional gastric lavage fluid sampling devices, significantly improving the accuracy of gastric cancer screening and patient comfort, and has high clinical application value. Attached Figure Description

[0019] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 This is a perspective view of the present invention;

[0021] Figure 2 This is a cross-sectional view of the front part of the conduit in this utility model;

[0022] Figure 3 This is a perspective view of the inner tube in this utility model;

[0023] Figure 4 This is a perspective view of the rear part of the catheter in this utility model.

[0024] In the diagram: 1. Inner tube; 11. Guide strip; 12. Side hole; 13. Spring ring; 2. Outer tube; 21. Slide groove; 22. Limiting groove; 3. Three-way valve; 4. Filter screen; 41. Sealing cover; 5. Limiting ring; 51. Limiting block. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. The components of the embodiments of this utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0026] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0027] like Figure 1 , Figure 2 As shown, a sampling device for gastric lavage fluid screening for gastric cancer includes a catheter and a three-way valve 3. The catheter includes an inner tube 1 and an outer tube 2 coaxially nested together. The outer tube 2 can slide along the axial direction of the inner tube 1. The front end of the inner tube 1 has a side hole 12 that extends radially through it. The outer tube 2 completely covers the side hole 12 in the initial state. A limit component is provided at the rear end of the inner tube 1. When the limit component is driven, the outer tube 2 retracts to expose the side hole 12. The tail end of the inner tube 1 is connected to an lavage fluid injection channel and a negative pressure suction channel through the three-way valve 3. The negative pressure suction channel is connected in series with a negative pressure suction device and a collection bottle.

[0028] During insertion: the outer tube 2 completely covers the side hole 12 of the inner tube 1, preventing contact with the oral / esophageal mucosa during insertion and avoiding contaminants (such as saliva and bacteria) adhering to the outer wall of the catheter; during sampling: the outer tube 2 is retracted by the limiting component, exposing the side hole 12, and the irrigation fluid is injected into the stomach through the inner tube 1 and then recovered, with only the inner tube 1 contacting the gastric contents throughout the process; finally, in the retrieval stage: the outer tube 2 is reset to cover the side hole 12, avoiding secondary contamination when removed. This physical isolation design reduces the contamination rate from 35% of traditional single-layer catheters to below 10%, and is easy to operate, making it suitable for primary healthcare institutions.

[0029] like Figure 2 As shown, in some embodiments of this utility model, a spring coil 13 is fitted on the inner wall of the front end of the inner tube 1. The spring coil 13 is made of stainless steel or nickel-titanium alloy, embedded in the front end of the inner tube 1, and extends 3-5 cm in front of the side hole 12 to prevent the catheter from collapsing when the esophagus bends and to ensure that the side hole 12 always faces the stomach cavity.

[0030] As an example, the spring coil 13 is a helical spring coil 13, which enhances the radial support force.

[0031] like Figure 2 , Figure 3 As shown, in some embodiments of this utility model, the outer wall of the inner tube 1 is provided with two axial guide strips 11, and the inner wall of the outer tube 2 is provided with corresponding guide grooves to restrict the relative sliding direction. The cross-section of the guide strips 11 is dovetail-shaped, and the shape of the guide grooves matches, ensuring that the sliding only occurs along the axial direction and preventing rotational deviation.

[0032] like Figure 4 As shown, in some embodiments of this utility model, the limiting component includes a limiting ring 5 rotatably sleeved on the surface of the inner tube 1 and a sliding groove 21 penetrating the surface of the outer tube 2. A limiting block 51 is radially arranged on the surface of the limiting ring 5. The diameter of the limiting ring 5 is the same as the diameter of the inner tube 1. The sliding groove 21 is opened along the axial direction of the outer tube 2. A limiting groove 22 is also circumferentially opened at the end of the sliding groove 21 away from the limiting ring 5.

[0033] In the initial state, the limiting block 51 is misaligned with the slide groove 21, fixing the position of the outer tube 2. When the outer tube 2 needs to be retracted, the limiting ring 5 is rotated to match the limiting block 51 with the slide groove 21. The limiting block 51 slides along the slide groove 21 until it rotates and locks in the limiting groove 22, preventing the outer tube 2 from accidentally sliding. This improves the effect of preventing misoperation because it requires a dual action of rotation and pushing to unlock, preventing accidental retraction before sampling. In addition, the limiting block 51 produces a "click" sound when it enters the limiting groove 22, providing tactile feedback and indicating that the operation is in place.

[0034] like Figure 2As shown, in some embodiments of this utility model, the front end of the inner tube 1 is sequentially connected to a sealing cover 41 and a filter screen 4, with a side hole 12 located between them. The sealing cover 41 is made of medical-grade silicone and its front end is conical. The conical front end can guide the irrigation fluid to flow towards the side hole 12, avoiding diffusion to ineffective areas; while the filter screen 4 can intercept food residue and reduce impurities.

[0035] In some embodiments of this utility model, 4-6 side holes 12 are evenly distributed along the circumference of the inner tube 1, and the opening area of ​​a single side hole 12 is 1-2 mm. 2 Furthermore, the edges of the side holes 12 are rounded. The even distribution of multiple holes ensures uniform injection and recovery of the irrigation fluid, avoiding excessive local pressure that could damage the gastric mucosa; the rounded corner design reduces shear damage during cell passage and maintains cell integrity.

[0036] As an example, the side holes 12 are arranged in a hexagonal array to optimize fluid dynamics.

[0037] In some embodiments of this invention, the outer tube 2 is coated with a hydrophilic coating with a thickness of 5-10 μm and a coefficient of friction ≤0.15. The hydrophilic coating forms a lubricating layer upon contact with water, reducing frictional resistance with the mucous membrane.

[0038] In some embodiments of this invention, a ceramic filter element and a duckbill-shaped one-way valve are connected in series at the inlet of the negative pressure suction channel. The ceramic filter element has a pore size of 0.5 μm, and the one-way valve has an opening pressure of -50 to -80 mmHg. The ceramic filter element intercepts microorganisms and particulate matter, preventing contamination of the negative pressure equipment; the one-way valve can automatically open when the negative pressure reaches a threshold, preventing liquid backflow.

[0039] In the description of this specification, references to terms such as "an embodiment," "example," "specific example," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0040] The above are merely preferred embodiments of this utility model and are not intended to limit the scope of this utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A sampling device for gastric lavage fluid screening for gastric cancer, comprising a catheter and a three-way valve (3), characterized in that, The catheter includes an inner tube (1) and an outer tube (2) that are coaxially nested, and the outer tube (2) can slide along the axial direction of the inner tube (1); The inner tube (1) has a side hole (12) that is radially through the front end, and the outer tube (2) completely covers the side hole (12) in the initial state; the rear end of the inner tube (1) is provided with a limiting component, and when the limiting component is driven, the outer tube (2) retracts to expose the side hole (12); The tail end of the inner tube (1) is connected to the irrigation fluid injection channel and the negative pressure suction channel through the three-way valve (3), and the negative pressure suction channel is connected in series with the negative pressure suction device and the collection bottle.

2. The sampling device for gastric lavage fluid screening for gastric cancer according to claim 1, characterized in that, A spring ring (13) is fitted on the inner wall of the front end of the inner tube (1).

3. A sampling device for screening gastric cancer using gastric lavage fluid according to claim 1, characterized in that, The inner tube (1) has two axial guide strips (11) on its outer wall, and the outer tube (2) has a corresponding guide groove on its inner wall.

4. A sampling device for screening gastric cancer using gastric lavage fluid according to claim 1, characterized in that, The limiting assembly includes a limiting ring (5) rotatably sleeved on the surface of the inner tube (1) and a sliding groove (21) penetrating the surface of the outer tube (2). The surface of the limiting ring (5) is provided with a limiting block (51) in the radial direction. The diameter of the limiting ring (5) is the same as the diameter of the inner tube (1). The sliding groove (21) is opened along the axial direction of the outer tube (2). At the end of the sliding groove (21) away from the limiting ring (5), a limiting groove (22) is also circumferentially opened.

5. A sampling device for screening gastric cancer using gastric lavage fluid according to claim 1, characterized in that, The front end of the inner tube (1) is connected in sequence to a sealing cover (41) and a filter screen (4), and the side hole (12) is located between the two.

6. A sampling device for screening gastric cancer using gastric lavage fluid according to claim 5, characterized in that, The sealing cover (41) is made of medical-grade silicone and has a conical front end.

7. A sampling device for screening gastric cancer using gastric lavage fluid according to claim 1, characterized in that, Four to six side holes (12) are evenly distributed along the circumference of the inner tube (1), and the opening area of ​​a single side hole (12) is 1-2 mm. 2 Furthermore, the edges of the side holes (12) are rounded.

8. A sampling device for screening gastric cancer using gastric lavage fluid according to claim 1, characterized in that, The outer tube (2) is coated with a hydrophilic coating with a thickness of 5-10 μm and a friction coefficient ≤0.

15.

9. A sampling device for screening gastric cancer using gastric lavage fluid according to claim 1, characterized in that, The negative pressure suction channel inlet is equipped with a ceramic filter element and a duckbill-shaped one-way valve connected in series. The ceramic filter element has a pore size of 0.5μm, and the one-way valve has an opening pressure of -50 to -80 mmHg.

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