Device suitable for adventitial denervation of the pulmonary artery

Abstract

The embodiment of the present application relates to the field of treatment by applying current, in particular to a device suitable for epicardial denervation of pulmonary artery, which comprises an operating member, an ablation execution member, a wire and a radio frequency providing member. The wire is arranged in the operating member and is arranged to connect the ablation execution member and the radio frequency providing member, so that the radio frequency providing member provides current to the ablation execution member through the wire; the operating member is connected with the ablation execution member and can operate the ablation execution member to make the ablation execution member surround the epicardium of the pulmonary artery; when the ablation execution member surrounds the epicardium of the pulmonary artery, the radio frequency providing member provides current to the ablation execution member, and the ablation execution member denervates the epicardium of the pulmonary artery. The device suitable for epicardial denervation of pulmonary artery provided by the embodiment of the present application can operate the ablation execution member to make the ablation execution member surround the epicardium of the pulmonary artery, so that the current can act on the nerves on the epicardium of the pulmonary artery, and the nerves on the epicardium of the pulmonary artery can be effectively removed.

Description

Technical Field

[0001] Embodiments of this application relate to the field of treatment by applying an electric current, and more specifically to a device suitable for denervating the adventitia of the pulmonary artery. Background Technology

[0002] The statements herein are provided merely as background information in connection with this application and do not necessarily constitute prior art.

[0003] Previous studies have confirmed a close relationship between the development and progression of pulmonary hypertension and the pulmonary sympathetic nervous system. Therefore, pulmonary artery denervation has become an important treatment method for pulmonary hypertension. However, radiofrequency devices typically used for pulmonary artery sympathetic denervation are typically applied at the pulmonary artery intima level. Increasing research indicates that the pulmonary sympathetic nervous system is concentrated in the pulmonary adventitia. Due to limitations in energy conduction, current pulmonary artery denervation techniques performed through the pulmonary artery intima still have many limitations. This device is primarily used for simultaneous pulmonary adventitia denervation during cardiac surgery. Utility Model Content

[0004] A brief overview of this application is provided below to offer a basic understanding of certain aspects thereof. It should be understood that this overview is not an exhaustive summary of the application. It is not intended to identify key or essential parts of the application, nor is it intended to limit its scope. Its purpose is merely to present certain concepts in a simplified form as a prelude to the more detailed description that follows.

[0005] To address the aforementioned problems, embodiments of this application provide a device suitable for denervating the adventitia of the pulmonary artery, comprising an operating element, an ablation actuator, a lead, and a radio frequency (RF) supply element. The lead is disposed within the operating element and configured to connect the ablation actuator and the RF supply element, such that the RF supply element provides current to the ablation actuator through the lead. The operating element is connected to the ablation actuator and is capable of operating the ablation actuator to surround the adventitia of the pulmonary artery. When the ablation actuator surrounds the adventitia of the pulmonary artery, the RF supply element provides current to the ablation actuator, thereby denervating the adventitia of the pulmonary artery.

[0006] The device for adventitia denervation of the pulmonary artery provided in the embodiments of this application operates an ablation actuator by an actuating element so that the ablation actuator surrounds the outside of the pulmonary artery, thereby enabling the current supplied by the radiofrequency supply element to the ablation actuator through a wire to act on the nerves on the adventitia of the pulmonary artery, so as to effectively remove the nerves on the adventitia of the pulmonary artery.

[0007] Furthermore, the ablation actuator includes a metal element and a flexible covering, the flexible covering covering the side of the metal element opposite to the adventitia of the pulmonary artery; the ablation actuator is capable of manipulating the flexible covering to surround the adventitia of the pulmonary artery; when the flexible covering surrounds the adventitia of the pulmonary artery, the side of the metal element without the flexible covering is in contact with the adventitia of the pulmonary artery.

[0008] Furthermore, the metal parts and flexible coverings are shaped into strips.

[0009] Furthermore, each end of the flexible covering is provided with a mating part, so that when the flexible covering surrounds the adventitia of the pulmonary artery, the mating part at one end of the flexible covering engages with the mating part at the other end.

[0010] Furthermore, the mating parts are snap-fit ​​structures.

[0011] Furthermore, the mating component has a magnetic structure.

[0012] Furthermore, one end of the flexible covering has a protruding fitting, and the other end of the flexible covering has a recessed fitting. The protruding fitting can be inserted into the recessed fitting so that the two fit together.

[0013] Furthermore, recessed mating parts are formed at multiple different locations on the other end of the flexible covering.

[0014] Furthermore, a predetermined magnetic pole with a magnetic structure is formed at one end of the flexible covering, and magnetic poles that attract the predetermined magnetic pole are formed at multiple different positions at the other end of the flexible covering.

[0015] Furthermore, the other end of the flexible covering forming the recessed mating part is the end of the flexible covering closer to the operating part.

[0016] Furthermore, the other end of the flexible covering that forms a magnetic pole that attracts the predetermined magnetic pole is the end of the flexible covering that is close to the operating element. Attached Figure Description

[0017] Other objects and advantages of this application will become apparent from the following description of embodiments of this application with reference to the accompanying drawings, and will help to provide a comprehensive understanding of this application.

[0018] Figure 1 This is a schematic diagram of a device for denervating the adventitia of the pulmonary artery, provided in an embodiment of this application.

[0019] Figure 2 yes Figure 1 The diagram shows a schematic of the structure of a device suitable for denervating the adventitia of the pulmonary artery during the removal of nerves from the adventitia of the pulmonary artery.

[0020] Figure 3 yes Figure 1 The diagram shows a structural schematic of a device suitable for denervating the adventitia of the pulmonary artery from another angle.

[0021] Explanation of reference numerals in the attached figures:

[0022] 100. Denervation device;

[0023] 10. Operating component; 20. Ablation actuator; 21. Metal component; 22. Flexible covering; 220. Fitting component;

[0024] 200. Pulmonary artery; 201. Adventitia.

[0025] It should be noted that the accompanying drawings are not necessarily drawn to scale, but are shown only in a schematic manner without affecting the reader's understanding. Detailed Implementation

[0026] Exemplary embodiments of this application will be described below with reference to the accompanying drawings. For clarity and brevity, not all features of actual implementations are described in the specification. However, it should be understood that many implementation-specific decisions must be made in the development of any such actual embodiment to achieve the developer's specific goals, such as complying with constraints related to the system and business, and these constraints may vary depending on the implementation. Furthermore, it should be understood that while development work can be very complex and time-consuming, such development work is merely a routine task for those skilled in the art who benefit from the content of this application.

[0027] It should also be noted that, in order to avoid obscuring this application with unnecessary details, only the equipment structure and / or processing steps closely related to the solution according to this application are shown in the accompanying drawings, while other details that are not closely related to this application are omitted.

[0028] In related technologies, devices for denervating the sympathetic nervous system are typically inserted into the pulmonary artery via a peripheral vein to remove the sympathetic nerves from the pulmonary artery's intima. However, since the sympathetic nerves in the pulmonary artery are distributed not only in the intima but also in the adventitia, insufficient, non-transmural radiofrequency ablation cannot guarantee effective denervation. Simply increasing the radiofrequency ablation energy will inevitably increase the risk of vascular damage, leading to catastrophic consequences. Currently, there is no suitable device or equipment for denervating the adventitia of the pulmonary artery; how to denervate the adventitia of the pulmonary artery remains an unsolved problem.

[0029] To address the aforementioned issues, embodiments of this application provide a device suitable for denervating the adventitia of the pulmonary artery.

[0030] See Figure 1 , Figure 2 and Figure 3 , Figure 1 This is a schematic diagram of the structure of a device 100 for denervating the adventitia 201 of the pulmonary artery 200, provided in an embodiment of this application. Figure 2 yes Figure 1 The diagram shown illustrates the structure of the device 100 for denervating the adventitia 201 of the pulmonary artery 200 during the removal of nerves from the adventitia 201 of the pulmonary artery 200. Figure 3 yes Figure 1 The schematic diagram shown is of another angle of the device 100 for denervating the adventitia 201 of the pulmonary artery 200. The device 100 for denervating the adventitia 201 of the pulmonary artery 200 (hereinafter referred to as denervation device 100) provided in the embodiments of this application may include an operating element 10, an ablation actuator 20, a lead wire, and a radio frequency supply element.

[0031] A lead wire is disposed within the operating element 10 and is configured to connect the ablation actuator 20 and the radio frequency supply element, such that the radio frequency supply element provides current to the ablation actuator 20 through the lead wire; the operating element 10 is connected to the ablation actuator 20 and is capable of operating the ablation actuator 20 to surround the adventitia 201 of the pulmonary artery 200; when the ablation actuator 20 surrounds the adventitia 201 of the pulmonary artery 200, the radio frequency supply element provides current to the ablation actuator 20, and the ablation actuator 20 denervates the adventitia 201 of the pulmonary artery 200.

[0032] The denervation device 100 provided in the embodiments of this application operates the ablation actuator 20 by the operating member 10 so that the ablation actuator 20 surrounds the outside of the pulmonary artery 200, so that the current supplied by the radio frequency supply member to the ablation actuator 20 through the wire can act on the nerves on the adventitia 201 of the pulmonary artery 200, so as to effectively remove the nerves on the adventitia 201 of the pulmonary artery 200.

[0033] The denervation device 100 provided in the embodiments of this application is suitable for denervating the adventitia 201 of the pulmonary artery 200 during cardiac surgery to remove the sympathetic nerves from the adventitia 201 of the pulmonary artery 200.

[0034] The radio frequency (RF) supply, for example, is an RF power supply, not shown in the figure. It can be located on one side of the operating element 10, and those skilled in the art can configure the RF supply according to actual needs.

[0035] See Figure 3In some embodiments, the ablation actuator 20 may include a metal element 21 and a flexible covering 22, the flexible covering 22 covering the side of the metal element 21 opposite to the adventitia 201 of the pulmonary artery 200; the actuating element 10 is operable to manipulate the flexible covering 22 such that the flexible covering 22 surrounds the adventitia 201 of the pulmonary artery 200; when the flexible covering 22 surrounds the adventitia 201 of the pulmonary artery 200, the side of the metal element 21 without the flexible covering 22 is in contact with the adventitia 201 of the pulmonary artery 200. In such an embodiment, the flexible covering 22 covers the side of the metal member 21 facing away from the adventitia 201 of the pulmonary artery 200, so that when the operating member 10 operates the flexible covering 22 to surround the adventitia 201 of the pulmonary artery 200, the side of the metal member 21 without the flexible covering 22 can contact the adventitia 201 of the pulmonary artery 200. Since the metal member 21 is conductive, the current provided by the radio frequency providing member can be transmitted to the adventitia 201 of the pulmonary artery 200 through the metal member 21 to effectively remove the nerves of the adventitia 201 of the pulmonary artery 200.

[0036] In some embodiments, the radio frequency provider is capable of providing current to the metal element 21, which denervates the adventitia 201 of the pulmonary artery 200.

[0037] In some embodiments, the flexible covering 22 may be made of a flexible insulating material.

[0038] In some embodiments, the operating member 10 can manipulate the flexible covering 22 to move one end of the flexible covering 22 away from the operating member 10 toward the operating member 10, so that the flexible covering 22 can surround the adventitia 201 of the pulmonary artery 200.

[0039] See Figure 3 In some embodiments, the metal element 21 and the flexible covering 22 are configured as strips. In such embodiments, the metal element 21 is configured as a strip, which gives the metal element 21 a certain degree of flexibility, so that when the flexible covering 22 surrounds the adventitia 201 of the pulmonary artery 200, the metal element 21 can also surround the adventitia 201 of the pulmonary artery 200.

[0040] See Figure 3In some embodiments, the flexible covering 22 is provided with mating members 220 at both ends, so that when the flexible covering 22 surrounds the adventitia 201 of the pulmonary artery 200, the mating member 220 at one end of the flexible covering 22 engages with the mating member 220 at the other end. In such embodiments, the engagement of the mating members 220 at both ends of the flexible covering 22 allows the flexible covering 22 to surround the entire circumference of the adventitia 201 of the pulmonary artery 200, thereby facilitating the thorough removal of nerves from the adventitia 201 of the pulmonary artery 200; simultaneously, the engagement of the mating members 220 at both ends of the flexible covering 22 allows the flexible covering 22 and the metal member 21 to remain in the surrounding position when the radio frequency supply member provides current to the metal member 21, so that the current reaching the metal member 21 can remove the nerves from the adventitia 201 of the pulmonary artery 200 in the surrounding position.

[0041] In some embodiments, the operating member 10 can operate the end of the flexible covering 22 away from the operating member 10 to move toward the operating member 10, so that the mating member 220 disposed at the end of the flexible covering 22 away from the operating member 10 engages with the mating member 220 at the end of the flexible covering 22 close to the operating member 10, thereby enabling the flexible covering 22 to surround the adventitia 201 of the pulmonary artery 200.

[0042] In some embodiments, the mating member 220 is a snap-fit ​​structure. In such embodiments, the mating is achieved by the interlocking of the snap-fit ​​structures at both ends of the flexible covering 22, so that the flexible covering 22 can surround the adventitia 201 of the pulmonary artery 200, which helps to enhance the stability of the mating between the mating members 220.

[0043] In some embodiments, the operating member 10 can operate the end of the flexible covering 22 away from the operating member 10 to move toward the operating member 10, so that the buckle provided at the end of the flexible covering 22 away from the operating member 10 engages with the buckle at the end of the flexible covering 22 close to the operating member 10, thereby enabling the flexible covering 22 to surround the adventitia 201 of the pulmonary artery 200.

[0044] In some embodiments, the mating member 220 is a magnetic structure. In such embodiments, mating is achieved by the mutual attraction of the magnetic structures disposed at both ends of the flexible covering 22, so that the flexible covering 22 can surround the adventitia 201 of the pulmonary artery 200. This simplifies the operation of surrounding the flexible covering 22 with the adventitia 201 of the pulmonary artery 200 and reduces operation time.

[0045] In some embodiments, one end of the flexible covering 22 has a protruding fitting member 220, and the other end of the flexible covering 22 has a recessed fitting member 220. The protruding fitting member 220 can be inserted into the recessed fitting member 220 to achieve a fit. In such an embodiment, the fitting is achieved by inserting the protruding fitting member 220 formed at one end of the flexible covering 22 into the recessed fitting member 220 formed at the other end of the flexible covering 22, so that the flexible covering 22 can surround the adventitia 201 of the pulmonary artery 200, which facilitates the rapid fitting of the fitting members at both ends of the flexible covering 22.

[0046] In some embodiments, recessed fittings 220 are formed at multiple different locations at the other end of the flexible covering 22. Since the adventitia 201 of different pulmonary arteries 200 have different diameters, embodiments of this application, by forming multiple recessed fittings 220 at multiple different locations at the other end of the flexible covering 22, enable the flexible covering 22 to surround the adventitia 201 of multiple pulmonary arteries 200 with different diameters, thereby enabling the removal of nerves from the adventitia 201 of multiple pulmonary arteries 200 with different diameters.

[0047] In some embodiments, a predetermined magnetic pole with a magnetic structure is formed at one end of the flexible covering 22, and magnetic poles attracted to the predetermined magnetic poles are formed at multiple different positions at the other end of the flexible covering 22. Since the adventitia 201 of different pulmonary arteries 200 have different diameters, the embodiments of this application, through the above-described arrangement, enable the flexible covering 22 to surround the adventitia 201 of multiple pulmonary arteries 200 with different diameters, thereby removing nerves from the adventitia 201 of multiple pulmonary arteries 200 with different diameters; at the same time, the predetermined magnetic poles can be matched with each other through the mutual attraction between the predetermined magnetic poles.

[0048] In some embodiments, the other end of the flexible covering 22 forming the recessed mating member 220 is the end of the flexible covering 22 near the operating member 10. Since the recessed mating member 220 and the protruding mating member 220 are mated by inserting the protruding mating member 220 into the recessed mating member 220, and when the operating member 10 operates the flexible covering 22, the end of the flexible covering 22 away from the operating member 10 will move towards the operating member 10, therefore, in the embodiments of this application, by setting the recessed mating member 220 to be formed at the end of the flexible covering 22 near the operating member 10, it is easier for the recessed mating member 220 and the protruding mating member 220 to be aligned, thereby facilitating the insertion of the protruding mating member 220 into the recessed mating member 220 and realizing the mating members 220 at both ends of the flexible covering 22.

[0049] In some embodiments, the other end of the flexible covering 22 that forms a magnetic pole attracted to a predetermined magnetic pole is the end of the flexible covering 22 closest to the operating member 10. In such an embodiment, the above arrangement facilitates the operating member 10 to operate the end of the flexible covering 22 away from the operating member 10 to move toward the operating member 10, thereby facilitating the continuous approach of the magnetic pole at the end of the flexible covering 22 away from the operating member 10 to the predetermined magnetic pole at the end of the flexible covering 22 closest to the operating member 10, so as to achieve engagement through the magnetism of the two magnetic structures.

[0050] Regarding the embodiments of this application, it should also be noted that, without conflict, the embodiments of this application and the features in the embodiments can be combined with each other to obtain new embodiments.

[0051] The above are merely specific embodiments of this application, but the scope of protection of this application is not limited thereto. The scope of protection of this application shall be determined by the scope of the claims.

Claims

1. A device for denervating the adventitia of the pulmonary artery, characterized in that, It includes: Operating components, ablation actuators, leads, and radio frequency supply components. The wire is disposed within the operating element and is configured to connect the ablation actuator and the radio frequency supply element, such that the radio frequency supply element supplies current to the ablation actuator through the wire. The ablation device is connected to the ablation actuator and is operable to cause the ablation actuator to surround the adventitia of the pulmonary artery; When the ablation actuator surrounds the adventitia of the pulmonary artery, the radio frequency provider supplies current to the ablation actuator, and the ablation actuator denervates the adventitia of the pulmonary artery.

2. The apparatus according to claim 1, characterized in that, The ablation actuator includes a metal component and a flexible covering, the flexible covering covering the side of the metal component opposite to the adventitia of the pulmonary artery; The actuating element is capable of manipulating the flexible covering so that the flexible covering surrounds the adventitia of the pulmonary artery; When the flexible covering surrounds the adventitia of the pulmonary artery, the side of the metal member without the flexible covering contacts the adventitia of the pulmonary artery.

3. The apparatus according to claim 2, characterized in that, The metal component and the flexible covering are configured into a strip shape.

4. The apparatus according to claim 3, characterized in that, The flexible covering is provided with mating parts at both ends, so that when the flexible covering surrounds the adventitia of the pulmonary artery, the mating part at one end of the flexible covering engages with the mating part at the other end.

5. The apparatus according to claim 4, characterized in that, The mating component has a snap-fit ​​structure.

6. The apparatus according to claim 4, characterized in that, The mating component has a magnetic structure.

7. The apparatus according to claim 4, characterized in that, One end of the flexible covering has a protruding fitting, and the other end of the flexible covering has a recessed fitting. The protruding fitting can be inserted into the recessed fitting to make them engage.

8. The apparatus according to claim 7, characterized in that, The recessed fittings are formed at multiple different locations on the other end of the flexible covering.

9. The apparatus according to claim 6, characterized in that, One end of the flexible covering has a predetermined magnetic pole with a magnetic structure, and multiple different positions at the other end of the flexible covering have magnetic poles that attract the predetermined magnetic pole.

10. The apparatus according to claim 8, characterized in that, The other end of the flexible covering forming the recessed mating member is the end of the flexible covering that is close to the operating member.

11. The apparatus according to claim 9, characterized in that, The other end of the flexible covering that forms a magnetic pole that attracts the predetermined magnetic pole is the end of the flexible covering that is close to the operating member.

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