A laboratory mouse tail vein injection device

Abstract

The utility model relates to injection device technical field, and disclose a mouse tail intravenous injection device for laboratory, including moving block, the hydraulic pressure rod is rotatably connected with the moving block bottom through the shaft, the injection cylinder is fixedly installed at the hydraulic pressure rod telescopic end, the upper portion of injection cylinder is fixedly sleeved with the air pump, the injection cylinder front part is equipped with the filling port, the exhaust hole is arranged on the filling port, the annular groove is equipped with the right side of the filling port on the injection cylinder, the electric push rod is fixedly installed in the right side of hydraulic pressure rod and the bottom of moving block, the electric push rod telescopic end is rotatably connected with the guide ring through the shaft, the guide ring is in accord with the annular groove, adjusts the injection angle of injection cylinder through the electric push rod, improves injection accuracy, avoids the angle deviation and causes the risk of adverse reaction, utilizes the thread and replaces the injection needle head quickly, can replace the injection needle head of abrasion or blockage quickly, and then improves injection efficiency, avoids discarding the complete instrument, reduces the waste of consumables.

Description

Technical Field

[0001] This utility model relates to the field of injection device technology, and in particular to a laboratory mouse tail vein injection device. Background Technology

[0002] Laboratory mice are among the most widely used experimental animals in life science research. Due to their high genetic similarity to humans, rapid reproduction rate, and low breeding cost, they are crucial in disease simulation, drug development, and basic biological research. Mice are widely used to simulate human diseases, evaluate drug effects, and explore gene functions. They must be raised in a clean environment free of specific pathogens, with strict control of temperature, humidity, ventilation, and hygiene standards to ensure reliable experimental results. With the advancement of gene editing technology, laboratory mice are continuously driving medical research towards precision.

[0003] In the prior art, mouse tail vein injection is mostly performed manually. However, manual operation is prone to angle deviation due to hand tremors and uneven force, making it difficult to accurately control the injection angle and ensure compliance with operating standards. This increases the risk of tissue damage and drug leakage in mice caused by improper angle, affecting experimental results. Moreover, the injection device is often disposable, which easily leads to waste of consumables. Therefore, in order to solve the above problems, this utility model proposes a laboratory mouse tail vein injection device. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides a laboratory mouse tail vein injection device. The device features precise and stable injection angle adjustment via an electric plunger, avoiding angular deviations and reducing risks such as tissue damage and drug leakage. The threaded design facilitates needle replacement, ensuring compatibility with different needle sizes and improving device applicability. It also allows for quick replacement of worn or clogged needles, thereby increasing injection efficiency, avoiding the discarding of complete instruments, and reducing consumable waste.

[0005] This utility model provides the following technical solution: a laboratory mouse tail vein injection device, comprising a movable block, a hydraulic rod movably connected to the bottom of the movable block via a shaft, an injection cylinder fixedly installed at the telescopic end of the hydraulic rod, an air pump fixedly sleeved on the upper part of the injection cylinder, an injection port with an exhaust hole at the front of the injection cylinder, an annular groove on the injection cylinder to the right of the injection port, an electric actuator fixedly installed at the bottom of the movable block to the right of the hydraulic rod, a guide ring movably connected to the telescopic end of the electric actuator via a shaft, the guide ring engaging with the annular groove, a piston movably connected to the inner cavity of the injection cylinder, a thread on the outer right end of the injection cylinder, an injection needle at the right end of the injection cylinder, the left part of the inner cavity of the injection needle engaging with the thread, the injection angle of the injection cylinder being adjusted by the electric actuator to improve injection accuracy and avoid adverse risks caused by angle deviation, the thread allows for quick replacement of the injection needle, quickly replacing worn or clogged injection needles, thereby improving injection efficiency, avoiding the discarding of complete instruments, and reducing waste of consumables.

[0006] Preferably, the injection needle has a base plate at its bottom, and a support plate is fixedly installed on the upper part of the base plate. There are four support plates, which are symmetrically distributed. A threaded rod is movably sleeved between the two rear support plates. The self-locking characteristic of the thread is used to stably maintain the position of the injection mechanism, prevent displacement caused by vibration or external force, and improve operational safety.

[0007] Preferably, a knob is fixedly installed at the left end of the threaded rod and to the left of the support plate. A slide rod is fixedly sleeved between the two support plates at the front. A slider is movably sleeved on the threaded rod and the slide rod respectively. Turning the knob drives the threaded rod to rotate, and the threaded rod drives the slider on it to move. The slider at the front moves synchronously on the slide rod. Relying on the precision and stability of mechanical transmission, the orientation parameters are accurately controlled.

[0008] Preferably, a movable rod is fixedly installed between the two sliders, and the middle part of the movable rod is fixedly sleeved with the movable block. A fixing strap is provided on the upper part of the base plate and on the right side of the support plate. There are two fixing straps. The two sliders drive the movable block to move to the appropriate position through the connection of the movable rod. The structure is simple and durable with low maintenance cost, not easily affected by complex environment, and has high reliability.

[0009] Compared with the prior art, the present invention has the following beneficial effects: 1. The injection angle is adjusted by using an electric actuator to drive the syringe barrel, which has the advantages of precision and stability. It avoids angle deviations caused by hand tremors or uneven force during manual operation, ensuring that the injection angle meets the operating standards and reducing the risk of tissue damage and drug leakage caused by improper angle. The needle can be replaced by using the engagement of the left side of the needle's inner cavity with the thread, which is conducive to compatibility with different needle sizes and improves the applicability of the device. Disassembly and installation can be completed with one hand, reducing the difficulty of operation for operators. At the same time, it is easy to quickly replace worn or clogged needles, thereby improving injection efficiency and avoiding the disposal of complete instruments due to needle blockage or damage, reducing the waste of consumables.

[0010] 2. The screw rod is rotated by turning the knob, which in turn moves the slider on it. The slider at the front moves synchronously on the slide rod. The two sliders are connected by a moving rod, which moves the moving block to the appropriate position for injection. The orientation of the injection mechanism is adjusted by rotating the screw rod. Relying on the precision, stability and controllability of mechanical transmission, the orientation parameters are precisely controlled. The self-locking characteristic of the screw thread is used to stably maintain the position of the injection mechanism, preventing displacement caused by vibration or external force, improving operational safety. The structure is simple and durable with low maintenance costs. It is not easily affected by complex environments and has high reliability. Attached Figure Description

[0011] Figure 1 This is a schematic diagram of the external structure of this utility model; Figure 2 This is a schematic diagram of the injection structure of this utility model; Figure 3 This is a schematic diagram of the expansion and contraction of the injection structure of this utility model; Figure 4 This is a schematic cross-sectional view of the injection structure of this utility model.

[0012] In the diagram: 1. Moving block; 2. Hydraulic rod; 3. Injector; 4. Air pump; 5. Filling port; 6. Annular groove; 7. Electric actuator; 8. Guide ring; 9. Piston; 10. Thread; 11. Injection needle; 12. Base plate; 13. Support plate; 14. Threaded rod; 15. Knob; 16. Slide rod; 17. Slider; 18. Moving rod; 19. Fixing strap. Detailed Implementation

[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0014] Please see Figures 1-4A laboratory mouse tail vein injection device includes a movable block 1. A hydraulic rod 2 is movably connected to the bottom of the movable block 1 via a shaft. An injection cylinder 3 is fixedly mounted on the telescopic end of the hydraulic rod 2. An air pump 4 is fixedly sleeved on the upper part of the injection cylinder 3. An injection port 5 is provided at the front of the injection cylinder 3, and an vent hole is provided on the injection port 5. Injection fluid is added into the inner cavity of the injection cylinder 3 through the injection port 5. Gas in the inner cavity of the injection cylinder 3 is discharged through the vent hole provided on the injection port 5. An annular groove 6 is provided on the injection cylinder 3 to the right of the injection port 5. The bottom of the movable block 1 and... An electric actuator 7 is fixedly installed to the right of the hydraulic rod 2. The telescopic end of the electric actuator 7 is movably connected to a guide ring 8 via a shaft. The guide ring 8 fits into the annular groove 6. A piston 9 is movably connected inside the injection cylinder 3. A thread 10 is opened on the outside of the right end of the injection cylinder 3. An injection needle 11 is provided at the right end of the injection cylinder 3. The left part of the inner cavity of the injection needle 11 engages with the thread 10. When the electric actuator 7 is activated, its telescopic end extends, and the injection cylinder 3 is adjusted through the guide ring 8 to adjust the injection angle. Compared with manual injection, this method is precise, controllable, stable, consistent, efficient, and safe. Advantages: Achieves millimeter-level precise adjustment and locking of the angle, avoiding angle deviations caused by hand tremors and uneven force during manual operation. Ensures the injection angle meets operating standards, reducing the risk of tissue damage and drug leakage caused by improper angle. Activating the hydraulic rod 2, through the engagement of the annular groove 6 and guide ring 8, moves the syringe 3, allowing the right end of the injection needle 11 to pierce the mouse's tail vein. Activating the air pump 4 pressurizes the left end of the syringe 3's inner cavity, causing the piston 9 to move to the right within the syringe 3's inner cavity, thereby injecting the solution into the mouse. After injection into the tail vein of a white rat, the various mechanisms are restored. The injection needle 11 is rotated and removed by engaging the left side of its inner lumen with the thread 10. This facilitates the replacement of the injection needle 11 for subsequent injections. It is compatible with injection needles 11 of different specifications, improving the compatibility of the device. Disassembly and installation can be completed with one hand without additional tools, reducing the difficulty of operation for staff. At the same time, it is convenient to quickly replace worn or clogged injection needles 11, thereby improving injection efficiency and avoiding the discarding of complete instruments due to needle blockage or damage, thus reducing the waste of consumables. The injection needle 11 has a base plate 12 at its bottom, and a support plate 13 is fixedly installed on the upper part of the base plate 12. There are four support plates 13, which are symmetrically distributed. A threaded rod 14 is movably sleeved between the two rear support plates 13. A knob 15 is fixedly installed on the left end of the threaded rod 14 and to the left of the support plate 13. A sliding rod 16 is fixedly sleeved between the two front support plates 13. A slider 17 is movably sleeved on the threaded rod 14 and the sliding rod 16, respectively. A moving rod 18 is fixedly installed between the two sliders 17. The middle part of the moving rod 18 is fixedly sleeved with a moving block 1. Two fixing straps 19 are provided on the upper part of the base plate 12 and to the right of the support plate 13. The fixing straps 19 are used to secure the needle. The mouse is fixed on the base plate 12 to improve its stability during injection. Turning the knob 15 drives the threaded rod 14 to rotate, which in turn drives the slider 17 on it to move. The front slider 17 moves synchronously on the slide rod 16. The two sliders 17 are connected by the moving rod 18 to move the moving block 1 to the appropriate position for injection. The orientation of the injection mechanism is adjusted by rotating the threaded rod 14. Relying on the precision, stability and controllability of mechanical transmission, the orientation parameters are precisely controlled. The self-locking characteristic of the thread is used to stably maintain the position of the injection mechanism, preventing displacement caused by vibration or external force, improving operational safety. The structure is simple, durable and has low maintenance costs. It is not easily affected by complex environments and has high reliability.

[0015] Working principle: First, the mouse is secured to the base plate 12 using the fixing strap 19 (made of elastic rope). Injection solution is added into the inner cavity of the syringe 3 through the injection port 5. Gas in the inner cavity of the syringe 3 is discharged through the vent hole on the injection port 5. Turning the knob 15 rotates the threaded rod 14, which in turn moves the slider 17 on it. The front slider 17 moves synchronously on the sliding rod 16. The two sliders 17 are connected by the moving rod 18, which moves the moving block 1 to the appropriate position. The operator holds the mouse's tail and determines the injection position, then activates the electric push rod 7. Extend the telescopic end of the syringe, and adjust the injection angle of the syringe 3 by driving the guide ring 8. Activate the hydraulic rod 2 and drive the syringe 3 to move through the engagement of the annular groove 6 and the guide ring 8, so that the right end of the injection needle 11 is inserted into the tail vein of the mouse. Start the air pump 4 to introduce gas into the left end of the inner cavity of the syringe 3 to pressurize it, driving the piston 9 to move to the right in the inner cavity of the syringe 3, thereby injecting the injection solution into the tail vein of the mouse. After the injection is completed, restore all mechanisms to their original positions, rotate the injection needle 11, and use the engagement of its left inner cavity with the thread 10 to remove the injection needle 11, making it easy to replace the injection needle 11 for subsequent injections.

Claims

1. A laboratory mouse tail vein injection device, comprising a movable block (1), characterized in that: The bottom of the movable block (1) is movably connected to a hydraulic rod (2) via a shaft. An injection cylinder (3) is fixedly installed at the telescopic end of the hydraulic rod (2). An air pump (4) is fixedly sleeved on the upper part of the injection cylinder (3). An injection port (5) is opened at the front of the injection cylinder (3). An exhaust hole is provided on the injection port (5). An annular groove (6) is opened on the injection cylinder (3) to the right of the injection port (5). An electric push rod (7) is fixedly installed at the bottom of the movable block (1) to the right of the hydraulic rod (2). A guide ring (8) is movably connected to the telescopic end of the electric push rod (7) via a shaft. The guide ring (8) fits into the annular groove (6). A piston (9) is movably connected in the inner cavity of the injection cylinder (3). A thread (10) is opened on the outside of the right end of the injection cylinder (3). An injection needle (11) is provided on the right end of the injection cylinder (3). The left part of the inner cavity of the injection needle (11) meshes with the thread (10).

2. The laboratory mouse tail vein injection device according to claim 1, characterized in that: The injection needle (11) has a base plate (12) at its bottom, and a support plate (13) is fixedly installed on the upper part of the base plate (12). There are four support plates (13) and they are symmetrically distributed. A threaded rod (14) is movably sleeved between the two support plates (13) at the rear.

3. The laboratory mouse tail vein injection device according to claim 2, characterized in that: A knob (15) is fixedly installed on the left end of the threaded rod (14) and to the left of the support plate (13). A slide rod (16) is fixedly sleeved between the two support plates (13) at the front. A slider (17) is movably sleeved on the threaded rod (14) and the slide rod (16).

4. The laboratory mouse tail vein injection device according to claim 3, characterized in that: A movable rod (18) is fixedly installed between the two sliders (17). The middle part of the movable rod (18) is fixedly sleeved with the movable block (1). A fixing strap (19) is provided on the upper part of the base plate (12) and to the right of the support plate (13). There are two fixing straps (19).

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