Temperature control catheter, hypothermia treatment instrument and drainage perfusion system

Abstract

The application provides a temperature control catheter, a sublow-temperature therapeutic instrument and a drainage perfusion system, the temperature control catheter has an input channel and an output channel, cooling medium flows through the input channel to cool the distal end of the temperature control catheter, and is recovered through the output channel; the distal end of the temperature control catheter is made of metal material and is used for heat exchange with a target part to realize sublow-temperature treatment. The temperature control catheter with the distal end made of metal material is used for sublow-temperature treatment, the distal end made of metal material can efficiently exchange heat with the cooling medium and the target part, and the sublow-temperature treatment effect is more efficient and accurate, and the proximal end made of conventional material can reduce heat transfer, avoid that the cooling medium absorbs more heat on the conveying path, and also avoid unnecessary stimulation to the patient.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a temperature-controlled catheter, a hypothermia therapy device, and a drainage and perfusion system. Background Technology

[0002] Clinical trials have shown that hypothermia (typically 32°C–34°C) can reduce metabolic rate and alleviate postoperative complications. For every 1°C decrease in temperature, the metabolic rate of brain tissue decreases by 6%–7%, reducing cell damage caused by hypoxia. Hypothermia can also suppress inflammatory responses, reduce the release of pro-inflammatory factors (such as IL-6 and TNF-α), and alleviate secondary damage.

[0003] Existing technologies use methods such as applying towels or ice blankets to lower the temperature, but this cooling method is relatively slow and it is difficult to accurately regulate the brain temperature to sub-low temperatures.

[0004] To address the shortcomings of existing technologies in controlling the hypothermia process, such as slow efficiency and low control precision, this invention provides a temperature-controlled catheter, a hypothermia therapy device, and a drainage and perfusion system. Summary of the Invention

[0005] To overcome the shortcomings of slow efficiency and low control precision in the existing technology for controlling the hypothermia process, the present invention provides a temperature-controlled catheter, a hypothermia therapy device, and a drainage and perfusion system.

[0006] The present invention provides a temperature-controlled catheter having an input cavity and an output cavity. A cooling medium flows through the input cavity to cool the distal end of the temperature-controlled catheter and is recovered through the output cavity. The distal end of the temperature-controlled catheter is made of metal and is used for heat exchange with the target site to achieve hypothermia treatment.

[0007] Optionally, the distal end of the temperature-controlled conduit is a blind end.

[0008] Optionally, the distal end of the temperature-controlled conduit is provided with an infusion hole and a drainage hole, and the cooling medium is physiological saline or artificial cerebrospinal fluid.

[0009] Furthermore, a temperature sensor is also provided at the drainage hole, with the probe of the temperature sensor facing outward from the drainage hole, for monitoring the sub-hypothermia treatment temperature of the target area.

[0010] Optionally, the distal outer wall of the temperature-controlled conduit is also provided with an intracranial pressure sensor for monitoring intracranial pressure.

[0011] The present invention also provides a hypothermia therapy device, including a control module, a temperature adjustment module, and the temperature control conduit described in any of the preceding claims; The temperature control module can adjust the temperature of the cooling medium injected into the input cavity of the temperature control conduit; The control module controls and adjusts the working state of the temperature control module.

[0012] Optionally, the control module adjusts the temperature of the target part to the target range within the target time period by controlling the working state of the temperature adjustment module.

[0013] The present invention also provides a drainage and perfusion system, including a control module, a temperature control module, and a temperature-controlled conduit as described in any of the preceding claims; The temperature control module can adjust the temperature of the cooling medium injected into the input cavity of the temperature control conduit; The control module controls the operating status of the temperature control module and the input and / or output of the cooling medium.

[0014] Optionally, the input volume of the cooling medium is measured by weighing the filling bag, and the output volume of the cooling medium is measured by weighing the drainage bag.

[0015] Furthermore, the control module controls the input amount of the cooling medium by adjusting the infusion pipeline switch and / or the working state of the peristaltic pump; the control module controls the output amount of the cooling medium by adjusting the drainage pipeline switch and / or the height of the drainage bag.

[0016] Optionally, the system also includes a display module for displaying intracranial temperature data, intracranial pressure data, input amount of cooling medium, and output amount of cooling medium.

[0017] The temperature-controlled catheter, hypothermia therapy device, and drainage and irrigation system of the present invention have at least the following beneficial effects: 1. Hypothermia treatment is performed using a temperature-controlled catheter with a metal distal end. The metal distal end can efficiently exchange heat with the cooling medium and the target area, achieving a more efficient and accurate hypothermia treatment effect. The conventional material proximal end can reduce heat transfer, prevent the cooling medium from absorbing too much heat in the delivery path, reduce cooling efficiency, and avoid unnecessary stimulation to non-target areas of the patient.

[0018] 2. In some implementations, the distal end of the temperature-controlled catheter is a blind end, so the cooling medium does not enter the human body, and its flow rate can be significantly increased, thereby increasing the circulation volume of the coolant. In other implementations, the distal end of the temperature-controlled catheter is equipped with drainage holes and irrigation holes, so that the cooling medium can directly exchange heat with the target area (such as the ventricle) through fluid mixing, which improves the efficiency of hypothermia treatment. Furthermore, the flow and drainage of the cooling medium can also improve the composition of cerebrospinal fluid in the patient's skull.

[0019] 3. The temperature sensor installed at the drainage port measures the temperature of the target area more accurately, which helps to achieve the hypothermia treatment effect more accurately. The intracranial pressure sensor installed on the outer wall of the distal end of the temperature control catheter measures the intracranial pressure, ensuring safety.

[0020] 4. By controlling the temperature of the target area in stages through the control module, brain tissue can be better protected.

[0021] 5. The cooling medium is adjusted to the required temperature by the temperature control module. In some implementations, the temperature is adjusted by a constant temperature chamber, and in others, the temperature is adjusted by a mesh structure that extends along the tube body, thus optimizing the temperature control effect. Attached Figure Description

[0022] To more clearly illustrate the technical solutions in this invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0023] Figure 1 This is one of the axial cross-sectional schematic diagrams of a temperature-controlled conduit provided by the present invention; Figure 2 This is the second axial cross-sectional view of a temperature-controlled conduit provided by the present invention; Figure 3 This is the third axial cross-sectional view of a temperature-controlled conduit provided by the present invention; Figure 4 -A is Figure 3 One example of a bottom-view schematic diagram of a temperature-controlled conduit; Figure 4 -B is Figure 3 Example 2: A bottom view of the temperature control conduit.

[0024] Figure label: 11-Distal end, 12-Proximal end, 21-Inlet cavity, 22-Outlet cavity, 23-Irrigation port, 24-Drainage port, 251-Temperature sensor, 252-Signal line, 253-Intracranial pressure sensor. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this invention. All other embodiments obtained by those skilled in the art based on the embodiments of this invention without creative effort are within the scope of protection of this invention.

[0026] The following is combined with Figures 1-4 This invention describes a temperature-controlled catheter, a hypothermia therapy device, and a drainage and perfusion system.

[0027] The present invention provides a temperature-controlled catheter having an input cavity and an output cavity. A cooling medium flows through the input cavity to cool the distal end of the temperature-controlled catheter and is recovered through the output cavity. The distal end of the temperature-controlled catheter is made of metal and is used for heat exchange with the target site to achieve hypothermia treatment.

[0028] Specifically, such as Figure 1 As shown, the temperature-controlled conduit includes a distal end 11 and a proximal end 12. The distal end 11 is made of a metal material, such as copper, stainless steel, titanium, titanium alloy, platinum-iridium alloy, etc., which has low cost and good thermal conductivity. Preferably, a copper metal tip is used for the distal end. The material of the proximal end 12 can be flexibly selected, such as polyethylene (PE), polypropylene (PP), polystyrene (PS), polyvinyl chloride (PVC), nylon, polyurethane (PU), thermoplastic polyurethane (TPU), polytetrafluoroethylene (PTFE), etc. The distal end 11 and the proximal end 12 are sealed together. An inlet cavity 21 and an outlet cavity 22 are formed inside the temperature-controlled conduit. Cooling medium is injected through the inlet cavity 21, which can reduce the temperature of the distal metal end 11. The distal metal end 11 is implanted into the target site and can efficiently exchange heat with the target site (such as the ventricle or brain parenchyma). The cooling medium can also be drained out of the body through the outlet cavity 22 to achieve hypothermia treatment. The proximal end 12, made of conventional material, can reduce heat transfer and prevent the cooling medium from absorbing too much heat in the delivery path, thus slowing down the temperature control speed.

[0029] Still refer to Figure 1 Based on the foregoing embodiments, in some embodiments, the distal end 11 of the temperature-controlled catheter is a blind end, and the input cavity 21 and the output cavity 22 are connected inside the distal end 11. That is, the input cavity 21 and the output cavity 22 form a circulation loop of cooling medium within the temperature-controlled catheter. The temperature of the metal distal end 11 of the temperature-controlled catheter is reduced by the continuously injected cooling medium, and the metal distal end 11 can efficiently exchange heat with the implantation site, achieving efficient hypothermia treatment. Since the cooling medium does not enter the human body, the flow rate of the cooling medium can be flexibly adjusted (allowing for higher flow rates) to change the temperature control efficiency.

[0030] Reference Figure 2 In some other embodiments, the distal end 11 of the temperature-controlled conduit is provided with an infusion port 23 and a drainage port 24. Specifically, the input cavity 21 and the output cavity 22 are separated within the temperature-controlled conduit, the infusion port 23 is located at the distal end of the input cavity 21, and the drainage port 24 is located at the distal end of the output cavity. Figure 2The illustration only shows the distal end 11 of the temperature-controlled catheter with one infusion port 23 and one drainage port 24. More infusion ports 23 and more drainage ports 24 can be added to the distal end of the temperature-controlled catheter. During use, the cooling medium injected into the input cavity 21 enters the intracranial cavity through the infusion port 23. The cooling medium can directly exchange heat with the target area (such as the ventricles or brain parenchyma), reducing the temperature of the target area. The cooling medium injected into the target area mixes with the cerebrospinal fluid and enters the output cavity 22 through the drainage port 24 for recovery, avoiding excessive intracranial pressure.

[0031] Understandably, since the cooling medium enters the cranium directly, it is necessary to use components that are harmless to brain tissue, such as artificial cerebrospinal fluid or saline solution. Furthermore, the cooling medium can partially replace the cerebrospinal fluid, improving its composition. For example, it can dilute the hematoma and drain the diluted hematoma + cerebrospinal fluid mixture to the outside of the skull. It can also continuously refresh the cerebrospinal fluid through circulation, removing harmful components (such as inflammatory factors, viral particles, viral nucleic acids, bilirubin, tumor cells, red blood cells, blood clots, etc.).

[0032] This embodiment uses a temperature-controlled catheter with a metal distal end for hypothermia treatment. The metal distal end can efficiently exchange heat with the cooling medium and the target area, achieving hypothermia treatment more efficiently and accurately. The conventional material proximal end can reduce heat transfer, prevent the cooling medium from absorbing too much heat in the delivery path, and avoid causing unnecessary stimulation to the patient.

[0033] Based on the previous embodiment, in some embodiments, a temperature sensor 251 is also provided at the drainage hole 24. By providing a temperature sensor 251 at the drainage hole 24, the temperature of the liquid entering the temperature-controlled conduit can be directly measured. The measured temperature can more accurately reflect the temperature state of the target area. The monitoring data from the temperature sensor 251 can be used to determine whether the target area has reached a sub-low temperature state, and can guide the adjustment of the cooling medium temperature.

[0034] Compared to installing a temperature sensor inside the temperature control conduit, this embodiment can avoid interference from the temperature of the cooling medium inside the temperature control conduit.

[0035] Furthermore, referring to Figure 3 and Figure 4 -A, the signal line 252 of the temperature sensor 251 can be placed inside the wall of the temperature control conduit, and a rigid wire can be used at the connection between the signal line 252 and the temperature sensor 251 to maintain it at the drainage hole 24. (Refer to...) Figure 4Alternatively, a perforated structure can be used to fix the temperature sensor 251 across the drainage hole 24. For example, a mesh perforated structure can be used to fix the temperature sensor 251 to the drainage hole, or a signal line 252 (the cladding of the signal line) can be used to support and fix the temperature sensor 251 across the drainage hole 24. Similarly, a temperature sensor can also be installed at the injection hole 23.

[0036] In other embodiments, the distal outer wall of the temperature-controlled conduit has a receiving groove, and the probe of the temperature sensor is placed inside the receiving groove. The open receiving groove exposes the temperature sensor probe. The signal line connecting the temperature sensor probe is located inside the wall of the temperature-controlled conduit and is used to transmit the monitored temperature data. Furthermore, the tube body at the receiving groove is made of thermal insulation material to further prevent the low-temperature cooling medium from cooling the temperature sensor inside the receiving groove and to avoid interference with the temperature data monitored by the temperature sensor. Preferably, the thermal insulation here refers to the material having a thermal conductivity of less than 0.065 W / m·K.

[0037] Furthermore, still referring to Figure 3 Furthermore, an intracranial pressure sensor 253 can be installed on the outer wall of the distal end 11 of the temperature-controlled catheter. This sensor can measure the intracranial pressure at the target site, thus preventing excessive input of cooling medium from causing excessive intracranial pressure and resulting in injury to the patient.

[0038] The present invention also provides a hypothermia therapy device, which can be understood in conjunction with the temperature control catheter provided above.

[0039] The hypothermia therapy device provided by the present invention includes: a control module, a temperature adjustment module, and a temperature control conduit as described in any of the preceding claims; The temperature control module can adjust the temperature of the cooling medium injected into the input cavity of the temperature control conduit; The control module controls the operating status of the temperature control module.

[0040] Specifically, a temperature control module can lower the temperature of the cooling medium, and its cooling temperature can be set. Examples of temperature control modules include refrigeration constant temperature chambers and thermoelectric coolers. A thermoelectric cooler is a device that generates cooling energy using the thermoelectric effect of semiconductors. It uses a conductor to connect two different metals; when a direct current is applied, the temperature at one junction decreases, and the temperature at the other junction increases. Thermoelectric coolers are characterized by being noiseless, vibration-free, requiring no refrigerant, small in size, and lightweight. They are also reliable, easy to operate, and easy to adjust their cooling capacity.

[0041] Furthermore, the temperature control module can be a mesh structure extending along the tube body, for example, a series of semiconductor cooling microplates extending along the tube body. In one example, the semiconductor cooling microplates are made into sheet-like structures 2 mm wide, which extend along the tube body and interweave into a mesh structure.

[0042] The control module can control and adjust the temperature of the cooling medium. For example, if the user sets the temperature of the constant temperature chamber, the control module will automatically control the constant temperature chamber to maintain the temperature set by the user. Or, if the temperature data of the target part is detected by the temperature sensor, the control module will control the working state of the temperature adjustment module according to the temperature data to achieve "adjusting the temperature of the target part to the sub-low temperature range within a limited time".

[0043] In this embodiment, the working state of the temperature control module is controlled by the control module, which accurately adjusts the cooling medium injected into the input cavity of the temperature control catheter to the required temperature. The distal end of the temperature control catheter is made of metal, which can efficiently exchange heat with the cooling medium and the target area, and achieve the hypothermia treatment effect more efficiently and accurately.

[0044] Based on the previous embodiment, in some embodiments, the control module adjusts the temperature of the target part to the target range within the target time period by controlling the working state of the temperature adjustment module.

[0045] Specifically, the temperature regulation process can be divided into multiple stages, with the temperature regulation module controlled separately in each stage to achieve the corresponding control target. For example, in the first stage, the temperature of the target area is gradually adjusted to 32-34℃ within a set time to avoid rapid cooling that could cause chills or organ damage; in the second stage, the body temperature is maintained at 32-34℃ during treatment; and in the third stage, the temperature is slowly raised back to the range of 36.5-37.5℃ after treatment.

[0046] Based on the foregoing embodiments, in some embodiments, the hypothermia therapy device further includes a display module for displaying relevant parameters during the hypothermia therapy process, such as displaying the temperature of the cooling medium in the input cavity of the temperature-controlled catheter, or displaying the temperature of the target site, the intracranial pressure of the target site, or the circulation rate of the cooling medium. Furthermore, in some embodiments, the user can also set relevant parameters during the hypothermia therapy process through the display module, such as setting a temperature control target, setting a temperature control time, etc.

[0047] This invention also provides a drainage and perfusion system, which can be understood in conjunction with the temperature-controlled catheter and hypothermia therapy device provided above.

[0048] The present invention provides a drainage and perfusion system, including a control module, a temperature control module, and a temperature-controlled conduit with a perfusion hole and a drainage hole at the distal end as described in the above embodiments.

[0049] The temperature control module can adjust the temperature of the cooling medium injected into the input cavity of the temperature control conduit; The control module adjusts and controls the working state of the temperature control module and the input and / or output of the cooling medium.

[0050] Specifically, a temperature control module can lower the temperature of the cooling medium, and its cooling temperature can be set. Examples of temperature control modules include refrigeration constant temperature chambers and thermoelectric coolers. A thermoelectric cooler is a device that generates cooling energy using the thermoelectric effect of semiconductors. It uses a conductor to connect two different metals; when a direct current is applied, the temperature at one junction decreases, and the temperature at the other junction increases. Thermoelectric coolers are characterized by being noiseless, vibration-free, requiring no refrigerant, small in size, and lightweight. They are also reliable, easy to operate, and easy to adjust their cooling capacity.

[0051] Furthermore, the temperature control module can be a mesh structure extending along the tube body, for example, a series of semiconductor cooling microplates extending along the tube body. In one example, the semiconductor cooling microplates are made into sheet-like structures 2 mm wide, which extend along the tube body and interweave into a mesh structure.

[0052] The control module can control and adjust the temperature of the cooling medium. For example, if the user sets the temperature of the constant temperature chamber, the control module will automatically control the constant temperature chamber to maintain the temperature set by the user. Or, if the temperature data of the target part is detected by the temperature sensor, the control module will control the working state of the temperature adjustment module according to the temperature data to achieve "adjusting the temperature of the target part to the sub-low temperature range within a limited time".

[0053] Because the temperature-controlled catheter is equipped with infusion and drainage holes, the cooling medium can enter the target area through the infusion holes, and the fluid in the target area can be drained out of the body through the drainage holes. On the one hand, the cooling medium entering the target area can perform heat exchange more efficiently, achieving the purpose of hypothermia treatment more effectively and accurately. On the other hand, the cooling medium also replaces the fluid in the target area, draining the cerebrospinal fluid containing harmful components such as inflammatory factors, viral particles, viral nucleic acids, bilirubin, tumor cells, red blood cells, and blood clots from the patient's skull to the outside, improving the composition of the cerebrospinal fluid. It is understood that the cooling medium at this time needs to use components that are harmless to the brain, such as artificial cerebrospinal fluid or physiological saline.

[0054] The control module can control and adjust the temperature of the cooling medium. For example, if the user sets the temperature of the constant temperature chamber (temperature control module), the control module will automatically control the constant temperature chamber to maintain the set temperature. Or, if the intracranial temperature sensor detects intracranial temperature data, the control module will adjust the working state of the temperature control module according to the temperature data, so that the intracranial temperature enters the sub-low temperature range.

[0055] The control module can also adjust the input and / or output of the cooling medium. Specifically, the input and output of the cooling medium directly affect the patient's intracranial pressure. To keep the patient's intracranial pressure within the normal range, the control module also needs to control the input and output of the cooling medium. In other words, it needs to control the net output, where net output = output - input. When the intracranial pressure sensor detects high intracranial pressure, the control module increases the net output; when the intracranial pressure sensor detects low intracranial pressure, the control module decreases the net output. The net output can be positive, achieving drainage; it can also be negative, achieving perfusion.

[0056] In addition, considering that the amount of input, output, and temperature of the cooling medium will all affect the temperature control effect of the target area, in a preferred embodiment, the net output can be determined first based on the measured intracranial pressure of the target area, then the planned input and planned output of the cooling medium can be determined based on the net output, and finally the temperature of the cooling medium input into the temperature control conduit that the temperature control module needs to regulate can be determined.

[0057] This embodiment controls the operation of the temperature control module through a control module, accurately adjusting the cooling medium injected into the input cavity of the temperature-controlled catheter to the required temperature. The distal end of the temperature-controlled catheter is made of metal, enabling efficient heat exchange with the cooling medium and the target site, achieving a more efficient and accurate hypothermia treatment effect. Furthermore, the cooling medium can enter the target site through the infusion port of the temperature-controlled catheter and exit outside the body through the drainage port, allowing the cooling medium to directly exchange heat with the target site, achieving the hypothermia treatment objective more efficiently and accurately. On the other hand, the cooling medium also performs fluid replacement with the target site, draining cerebrospinal fluid containing harmful components such as inflammatory factors, viral particles, viral nucleic acids, bilirubin, tumor cells, red blood cells, and blood clots from the patient's skull to the outside, thus improving the composition of the cerebrospinal fluid.

[0058] Based on the previous embodiment, in some embodiments, the input amount of the cooling medium is measured by weighing the filling bag, and the output amount of the cooling medium is measured by weighing the drainage bag.

[0059] Specifically, common ventricular drainage perfusion systems measure perfusion volume and drainage volume using flow sensors installed in the perfusion and drainage lines. However, flow sensors typically have some errors, especially when the drainage rate varies significantly. Existing technologies also determine drainage volume using volume markings on the drainage bag, but the drainage bag itself is easily deformed, resulting in lower measurement accuracy. This embodiment measures the weight of the perfusion bag using its built-in weighing structure, and then calculates the perfusion volume (i.e., the input volume into the cavity). Similarly, it measures the weight of the drainage bag using its built-in weighing structure and calculates the drainage volume (i.e., the output volume into the cavity), resulting in more accurate data. It is understood that both the perfusion bag and the drainage bag have their own weighing structures.

[0060] Furthermore, a weighing pan is used to measure the weight of the infusion bag and / or drainage bag, which are placed on the weighing pan during use.

[0061] Specifically, in common ventricular drainage surgeries, a drainage bag is suspended, and the height difference between the drainage bag and the ventricle is adjusted to allow sufficient force to drain the cerebrospinal fluid from the ventricle to the outside. However, if a weighing hook is used to measure the weight of the drainage bag, the bag is prone to swaying when adjusting the height, leading to unstable weighing readings. This embodiment uses a weighing pan, where the drainage bag is placed directly on the pan during use, preventing swaying. Alternatively, a weighing pan can be used for the perfusion bag to measure its weight and calculate the perfusion volume.

[0062] Based on the foregoing embodiments, in some embodiments, the control module controls the input amount of the cooling medium by adjusting the infusion pipeline switch and / or the working state of the peristaltic pump; the control module controls the output amount of the cooling medium by adjusting the drainage pipeline switch and / or the height of the drainage bag.

[0063] Specifically, the infusion bag is connected to the input cavity of the temperature-controlled conduit via an infusion pipeline. The infusion pipeline is equipped with an infusion pipeline switch and / or a peristaltic pump. The control module regulates whether cooling medium is input by controlling the opening / closing of the infusion pipeline switch, or regulates the input amount of cooling medium by controlling the speed of the peristaltic pump. The drainage bag is connected to the output cavity of the temperature-controlled conduit via a drainage pipeline. The drainage pipeline is equipped with a drainage pipeline switch. The control module regulates the drainage speed by adjusting the height of the drainage bag (e.g., adjusting the height of the weighing pan via a lifting structure), or regulates whether cooling medium is drained by controlling the opening / closing of the drainage pipeline switch.

[0064] Based on the foregoing embodiments, in some embodiments, the drainage and perfusion system further includes a display module for displaying relevant parameters during the hypothermia treatment process and the drainage and perfusion process.

[0065] Specifically, for example, it can display the temperature of the cooling medium in the input cavity of the temperature-controlled catheter; or, for example, display the temperature of the target site, the intracranial pressure of the target site, or, for example, the circulation rate of the cooling medium. It can also display intracranial temperature data, intracranial pressure data, the input volume of the cooling medium, and the output volume of the cooling medium.

[0066] Furthermore, in some embodiments, the user can also set relevant parameters during the hypothermia treatment process through the display module, such as setting a temperature control target, setting a temperature control time, etc.

[0067] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A temperature-controlled conduit, characterized in that, The temperature-controlled catheter has an input cavity and an output cavity. The cooling medium flows through the input cavity to cool the distal end of the temperature-controlled catheter and is recovered through the output cavity. The distal end of the temperature-controlled catheter is made of metal and is used for heat exchange with the target site to achieve hypothermia treatment.

2. The temperature-controlled conduit according to claim 1, characterized in that, The distal end of the temperature-controlled conduit is a blind end.

3. The temperature-controlled conduit according to claim 1, characterized in that, The temperature-controlled conduit is provided with an infusion hole and a drainage hole at its distal end, and the cooling medium is physiological saline or artificial cerebrospinal fluid.

4. The temperature-controlled conduit according to claim 3, characterized in that, A temperature sensor is also provided at the drainage hole, with the probe of the temperature sensor facing outward from the drainage hole, for monitoring the sub-hypothermia treatment temperature of the target area.

5. The temperature-controlled conduit according to claim 3, characterized in that, The distal outer wall of the temperature-controlled catheter is also equipped with an intracranial pressure sensor for monitoring intracranial pressure.

6. A hypothermia therapy device, characterized in that, It includes a control module, a temperature control module, and a temperature-controlled conduit as described in any one of claims 1-5; The temperature control module can adjust the temperature of the cooling medium injected into the input cavity of the temperature control conduit; The control module controls and adjusts the working state of the temperature control module.

7. The hypothermia therapy device according to claim 6, characterized in that, The control module adjusts the temperature of the target area to the target range within the target time period by controlling the working state of the temperature adjustment module.

8. A drainage and irrigation system, characterized in that, It includes a control module, a temperature control module, and a temperature-controlled conduit as described in any one of claims 3-5; The temperature control module can adjust the temperature of the cooling medium injected into the input cavity of the temperature control conduit; The control module controls the operating status of the temperature control module and the input and / or output of the cooling medium.

9. The drainage and irrigation system according to claim 8, characterized in that, The input volume of the cooling medium is measured by weighing the filling bag, and the output volume of the cooling medium is measured by weighing the drainage bag.

10. The drainage and irrigation system according to claim 8, characterized in that, The control module controls the input amount of the cooling medium by adjusting the infusion pipeline switch and / or the working state of the peristaltic pump; the control module controls the output amount of the cooling medium by adjusting the drainage pipeline switch and / or the height of the drainage bag.

11. The drainage and irrigation system according to claim 8, characterized in that, It also includes a display module for displaying intracranial temperature data, intracranial pressure data, input amount of cooling medium, and output amount of cooling medium.

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