A tablet structure for gout treatment

Abstract

The utility model discloses a kind of tablet structure for gout treatment, the utility model relates to pharmaceutical preparation technical field, including: short cylindrical capsule, its inside is filled with febuxostat medicament;Long cylindrical capsule, one end is fixedly connected with the short cylindrical capsule, its inside is filled with sodium bicarbonate;Annular capsule, it movably is sleeved in long cylindrical capsule outside, annular cavity is filled with enteric-coated tablet, and different function medicaments are stored in cabin, both ensure the stability of drug, and realize time sequence release effect. The characteristics that annular capsule can be flexibly used enable patient to decide whether to use auxiliary medicament according to actual needs, improve the individualization level of medication and improve the convenience of patient medication.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical preparation technology, specifically to a tablet structure for the treatment of gout. Background Technology

[0002] Gout is a metabolic disease caused by purine metabolism disorders, leading to excessive uric acid production and / or reduced excretion, resulting in elevated blood uric acid levels and the deposition of urate crystals in joints and other tissues. Patients often experience sudden joint redness, swelling, and severe pain. Treatment requires the simultaneous use of uric acid-lowering drugs to control disease progression and anti-inflammatory and analgesic drugs to relieve acute symptoms.

[0003] Currently, clinical practice often employs treatment regimens that involve administering different medications separately, but this approach suffers from complex medication regimens and poor patient compliance. Many existing combination formulations simply mix different drugs, which presents the following technical problems: First, physical or chemical interactions may occur between the different drugs, affecting the stability of the formulation; second, sequential drug release cannot be achieved, failing to optimize therapeutic efficacy; and third, some drugs are highly irritating to the gastrointestinal tract.

[0004] To address the aforementioned issues, a freely combinable capsule structure was designed to solve the technical problems mentioned above. Utility Model Content

[0005] To address the shortcomings of existing technologies, this invention provides a tablet structure for the treatment of gout, thus solving the technical problems mentioned in the background section.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a tablet structure for treating gout, comprising: Short cylindrical capsules filled with febuxostat; A long cylindrical capsule, one end of which is fixedly connected to the short cylindrical capsule, and its interior is filled with sodium bicarbonate; A ring-shaped capsule, which is movably fitted onto the outside of the elongated cylindrical capsule, with an enteric-coated tablets filling its annular cavity; The short cylindrical capsule and the long cylindrical capsule constitute a fixed core unit, and the annular capsule constitutes a separable auxiliary unit.

[0007] Preferably, the capsule shells of the short cylindrical capsule, the long cylindrical capsule, and the annular capsule are made of hydroxypropyl methylcellulose or pullulan.

[0008] Preferably, the sodium bicarbonate is in the form of an immediate-release powder formulation. Beneficial effects

[0009] This invention provides a tablet structure for the treatment of gout. Through a unique physical separation design, different functional drugs are stored in separate compartments, ensuring drug stability and achieving a time-sequential release effect. The ring-shaped capsule's flexible dispensing feature allows patients to decide whether to use adjuvant medications according to their actual needs, improving the individualization of medication and enhancing patient convenience. Attached Figure Description

[0010] Figure 1 This is a schematic diagram of the structure of a tablet for treating gout according to the present invention.

[0011] In the image: 1. Short cylindrical capsule; 2. Long cylindrical capsule; 3. Ring capsule; 4. Febuxostat preparation; 5. Sodium bicarbonate; 6. Enteric-coated tablet. Detailed Implementation

[0012] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0013] Please see Figure 1 This utility model provides a technical solution: a tablet structure for the treatment of gout, comprising: A short cylindrical capsule 1, which is filled with febuxostat 4; The long cylindrical capsule 2 has one end fixedly connected to the short cylindrical capsule 1, and its interior is filled with sodium bicarbonate 5. An annular capsule 3 is movably fitted onto the outside of the elongated cylindrical capsule 2, and its annular cavity is filled with an enteric-coated tablet 6. The short cylindrical capsule 1 and the long cylindrical capsule 2 constitute a fixed core unit, and the annular capsule 3 constitutes a separable auxiliary unit.

[0014] In this embodiment, the capsule shells of the short cylindrical capsule 1, the long cylindrical capsule 2, and the annular capsule 3 are made of hydroxypropyl methylcellulose or pullulan.

[0015] In this embodiment, the sodium bicarbonate 5 is further configured to be an immediate-release powder formulation.

[0016] Its detailed connection method is a well-known technology in this field. The following mainly introduces the working principle and process, and the specific work is as follows.

[0017] Example: A composite capsule structure for the treatment of gout. The structure mainly consists of three independent capsule units: a short cylindrical capsule 1, a long cylindrical capsule 2, and a ring-shaped capsule 3.

[0018] The short cylindrical capsule 1 is made of hydroxypropyl methylcellulose and is filled with febuxostat sustained-release microspheres 4. This formulation can slowly release the drug in the body, maintain a stable blood drug concentration, and provide a long-lasting uric acid-lowering therapeutic effect.

[0019] The long cylindrical capsule 2 is also made of hydroxypropyl methylcellulose, and one end of it is fixedly connected to the short cylindrical capsule 1 by a fitting method to form an inseparable whole. The long cylindrical capsule 2 is filled with a low dose of colchicine quick-release powder 5. This preparation can dissolve and release rapidly in a short time, and take effect quickly to relieve the pain and inflammation during an acute gout attack.

[0020] The ring-shaped capsule 3 is made of pullulan polysaccharide, and its internal annular cavity is filled with calcium carbonate powder 6. The removable design of the ring-shaped capsule allows it to be flexibly fitted onto the rod-shaped portion of a long cylindrical capsule, and its use can be chosen according to the patient's specific condition. The calcium carbonate component neutralizes stomach acid, provides protection for the gastrointestinal tract, and reduces potential irritation from the medication.

[0021] It should be noted that in this paper, relational terms such as first and second are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations.

Claims

1. A tablet structure for the treatment of gout, characterized in that, include: Short cylindrical capsule (1) filled with febuxostat (4). The long cylindrical capsule (2) is fixedly connected at one end to the short cylindrical capsule (1) and is filled with sodium bicarbonate (5). An annular capsule (3) is movably fitted onto the outside of the elongated cylindrical capsule (2), and its annular cavity is filled with an enteric-coated tablet (6). The short cylindrical capsule (1) and the long cylindrical capsule (2) constitute a fixed core unit, and the annular capsule (3) constitutes a separable auxiliary unit.

2. The tablet structure for treating gout according to claim 1, characterized in that... The capsule shells of the short cylindrical capsule (1), the long cylindrical capsule (2), and the annular capsule (3) are made of hydroxypropyl methylcellulose or pullulan.

3. The tablet structure for gout treatment according to claim 1, characterized in that... The sodium bicarbonate (5) is in the form of an immediate-release powder formulation.

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