Liquid drug concentration system

Abstract

The utility model belongs to liquid concentration technical field discloses a kind of liquid medicine concentration systems. The system includes concentration pot, heating device, negative pressure device and steam collection device, concentration pot has interlayer cavity and liquid medicine cavity, interlayer cavity and liquid medicine cavity are isolated and set and heat conduction connection, heating device is set to concentration pot outside and and interlayer cavity communication, heating medium can circulate flow between heating device and interlayer cavity, negative pressure device and steam collection device are all with liquid medicine cavity communication setting, negative pressure device can reduce the air pressure in liquid medicine cavity, steam collection device can collect the steam in liquid medicine cavity. System also has the advantages of uniform heating, high concentration efficiency, low energy consumption, and avoid local high temperature coking through external circulation heating, realize low-temperature mild evaporation in combination with negative pressure environment, effectively protect heat-sensitive active ingredients;While closed collection steam significantly improves production environment, meets GMP requirements.

Description

Technical Field

[0001] This utility model relates to the field of liquid concentration technology, and in particular to a pharmaceutical liquid concentration system. Background Technology

[0002] In the production of traditional Chinese medicine preparations, concentration of the medicinal liquid is one of the key technological steps, directly affecting the quality and yield of the final product. Currently, the industry widely uses traditional jacketed kettles as the main equipment for concentration. This type of equipment typically uses steam or heat transfer oil as the heating medium, transferring heat to the medicinal liquid inside the kettle through the jacket structure, promoting water evaporation, and thus achieving the purpose of concentration. This heating method based on the principle of heat conduction has been widely used by many traditional Chinese medicine manufacturers due to its relatively simple structure and intuitive operation.

[0003] However, this traditional jacketed kettle concentration technology has significant drawbacks. First, because the heating temperature of steam or heat transfer oil is usually much higher than 100°C, the localized areas of the drug solution in direct contact with the high-temperature jacket are prone to overheating or even charring. This not only affects product quality but also leads to the loss of active ingredients. Second, the heat transfer efficiency of this heating method is relatively low, resulting in uneven heating of the drug solution, which slows down the overall concentration process, making it time-consuming and significantly increasing energy consumption. More importantly, during the continuous high-temperature evaporation process, a large amount of water vapor is generated and diffuses into the production workshop, resulting in a long-term high-temperature and high-humidity working environment. This not only worsens the working conditions of the operators but, more importantly, makes it difficult to meet the strict cleanliness and environmental parameter requirements of the current Good Manufacturing Practice (GMP) for controlling the temperature and humidity of the production environment and preventing microbial contamination. In addition, high-temperature environments are particularly detrimental to the heat-sensitive active ingredients in traditional Chinese medicine liquids. These ingredients are prone to volatilization, decomposition, or chemical structure changes under prolonged exposure to temperatures exceeding 100°C, resulting in a significant reduction in content or even complete inactivation, which seriously damages the expected efficacy of the concentrated liquid and even the final drug.

[0004] Therefore, there is an urgent need for a drug concentration system to solve the above-mentioned technical problems. Utility Model Content

[0005] The purpose of this invention is to provide a drug concentration system that achieves a more efficient, gentle, energy-saving, and environmentally friendly concentration process that effectively protects the active pharmaceutical ingredients.

[0006] To achieve this objective, the present invention adopts the following technical solution:

[0007] A drug concentration system includes:

[0008] A concentration pot, the concentration pot having a jacketed cavity and a liquid medicine cavity, the jacketed cavity and the liquid medicine cavity being isolated from each other and thermally connected;

[0009] A heating device is provided outside the concentration pot and communicates with the jacketed cavity. The heating medium can circulate between the heating device and the jacketed cavity. The heating medium can absorb heat when flowing through the heating device and release heat to the liquid cavity when flowing through the jacketed cavity.

[0010] A negative pressure device is provided, which is connected to the liquid medicine chamber and is capable of reducing the air pressure inside the liquid medicine chamber;

[0011] A steam collection device is provided, which is connected to the liquid medicine chamber and is capable of collecting steam in the liquid medicine chamber.

[0012] In some embodiments, the heating device is further connected to a circulation pump, which drives the heating medium to circulate between the heating device and the jacket cavity.

[0013] In some embodiments, a buffer tank is connected between the heating device and the concentration pot, and the heating medium can flow sequentially into the buffer tank and the jacketed cavity.

[0014] In some embodiments, the liquid medicine chamber, the steam collection device, and the negative pressure device are sequentially connected and arranged.

[0015] In some embodiments, the steam collection device includes a condenser and a reservoir. The condenser is connected to one end of the reservoir near the liquid chamber. The condenser is capable of condensing the steam into condensate, and the reservoir is used to store the condensate and discharge it centrally.

[0016] In some embodiments, the top of the liquid reservoir is provided with a first inlet and a first outlet, the bottom of the liquid reservoir is provided with a second outlet, the condenser is connected to the first inlet, the negative pressure device is connected to the first outlet, and the second outlet is configured as a drain outlet.

[0017] In some embodiments, the top of the reservoir is provided with a second inlet, which is connected to a compressed air supply pipe.

[0018] In some embodiments, a one-way valve is connected between the negative pressure device and the first outlet, the one-way valve being used to prevent gas from flowing from the negative pressure device to the first outlet.

[0019] In some embodiments, the liquid chamber is connected to a liquid discharge pipeline, the liquid discharge pipeline is equipped with an electromagnetic switch valve, the concentration pot is equipped with a liquid level detector, and the liquid level detector and the electromagnetic switch valve are signal-connected; and / or,

[0020] The interlayer cavity is connected to a temperature sensor, and the temperature sensor is signal-connected to the heating device.

[0021] In some embodiments, the concentration vessel is connected to a stirrer capable of stirring the liquid in the liquid chamber; and / or,

[0022] The concentrator is connected to a hot water supply pipeline, which is used to inject hot water into the liquid chamber.

[0023] The above-mentioned technical solution has the following advantages or beneficial effects: This medicinal liquid concentration system, by adopting a synergistic technical solution of external circulating heating, negative pressure cooling, and closed steam collection, enables the heating medium to be uniformly heated externally before circulating back to the jacketed cavity for heat exchange, avoiding the local overheating problem that may occur when the heating medium (high-temperature steam or heat transfer oil) in a traditional jacketed kettle comes into direct contact with the kettle wall. Simultaneously, the negative pressure device significantly reduces the gas pressure inside the medicinal liquid chamber, allowing the medicinal liquid to boil and evaporate at a temperature far below the atmospheric boiling point (100℃). This combination fundamentally eliminates the risk of charring of the medicinal liquid due to localized high temperatures and greatly reduces the damage of high temperatures to heat-sensitive active ingredients (such as volatile and easily decomposable components) in traditional Chinese medicine, thereby maximizing the protection of the medicinal components and ensuring the quality and efficacy of the concentrated medicinal liquid. Furthermore, uniform heating and the negative pressure environment can significantly shorten the time required for the medicinal liquid to reach the desired concentration, improve the overall concentration efficiency, and effectively reduce the energy consumption per unit output. Furthermore, the steam collection device is connected to the liquid chamber, enabling timely and sealed collection of water vapor generated during evaporation. This vapor is then treated through condensation and other methods, effectively preventing large amounts of high-temperature, high-humidity steam from spreading into the production workshop. This fundamentally solves the problem of a hot and humid environment in the traditional jacketed kettle concentration process, significantly improving the operating environment, reducing the risk of microbial growth, and making the production environment easier to control and meet the stringent requirements of Good Manufacturing Practices (GMP) for temperature, humidity, cleanliness, and prevention of cross-contamination. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the drug concentration system in an embodiment of this utility model.

[0025] In the picture:

[0026] 1. Concentrator; 11. Liquid chamber; 12. Jacketed chamber; 13. Temperature sensor; 14. Liquid discharge pipeline; 15. Medium discharge pipeline; 16. Hot water supply pipeline; 17. Negative pressure suction pipeline; 18. Liquid level detector;

[0027] 2. Heating device;

[0028] 31. Condenser; 311. Cold water supply pipeline; 32. Liquid receiver; 321. First inlet; 322. First outlet; 323. Second outlet; 324. Second inlet;

[0029] 41. Vacuum pump; 42. Check valve;

[0030] 5. Circulating pump;

[0031] 6. Electromagnetic switch valve;

[0032] 7. Compressed air supply pipe. Detailed Implementation

[0033] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present invention and not intended to limit it. Furthermore, it should be noted that, for ease of description, the accompanying drawings show only the parts relevant to the present invention, not the entire structure.

[0034] In the description of this utility model, unless otherwise explicitly specified and limited, the terms "connected," "linked," "fixed," and "abutting" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0035] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0036] In the description of this embodiment, the terms "upper," "lower," "right," and "left," etc., refer to the orientation or positional relationship shown in the accompanying drawings. They are used only for ease of description and simplification of operation, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. In addition, the terms "first" and "second" are only used for distinction in description and have no special meaning.

[0037] The following is based on Figure 1 The present invention provides a drug concentration system in the embodiments thereof.

[0038] like Figure 1 As shown, in this embodiment, the drug concentration system includes a concentration pot 1, a heating device 2, a negative pressure device, and a steam collection device. The concentration pot 1 is the main working structure of the drug concentration system, and its interior is formed by a jacketed structure, creating a drug solution chamber 11 and a jacketed chamber 12. The drug solution chamber 11 is used to contain the drug solution to be concentrated. The jacketed chamber 12 is located outside the drug solution chamber 11 and is isolated from the drug solution chamber 11 by its wall, and is thermally connected. The heating device 2 is independently located outside the concentration pot 1 and is connected to the jacketed chamber 12 of the concentration pot 1 via a pipeline, forming a closed-loop heating medium circulation channel. During operation, the heating medium (e.g., water, oil, etc.) circulates between the heating device 2 and the jacketed chamber 12. When the heating medium flows through the heating device 2, it absorbs the heat provided by the heating device 2, and when the heating medium flows through the jacketed chamber 12, it releases heat towards the drug solution chamber 11, thereby causing the drug solution to evaporate.

[0039] Both the negative pressure device and the steam collection device are connected to the liquid chamber 11 via pipelines. During the concentration process, the negative pressure device actively reduces the air pressure inside the liquid chamber 11, thereby effectively lowering the boiling temperature of the liquid. The steam generated from heating the liquid is collected by the steam collection device, preventing large amounts of steam from dispersing throughout the production workshop.

[0040] This medicinal liquid concentration system employs a synergistic approach of external circulating heating, negative pressure cooling, and closed-loop steam collection. This allows the heating medium to be uniformly heated externally before circulating back to the jacketed cavity 12 for heat exchange, avoiding the localized overheating problems that can occur with direct contact between the heating medium (high-temperature steam or heat transfer oil) and the pot wall in traditional jacketed kettles. Simultaneously, the negative pressure device significantly reduces the gas pressure within the medicinal liquid chamber 11, enabling the medicinal liquid to boil and evaporate at a temperature far below the atmospheric boiling point (100°C). This combination fundamentally eliminates the risk of scorching due to localized high temperatures and greatly reduces the damage to heat-sensitive active ingredients (such as volatile and easily decomposable components) in traditional Chinese medicine, thereby maximizing the protection of the medicinal components and ensuring the quality and efficacy of the concentrated medicinal liquid. Furthermore, the uniform heating and negative pressure environment significantly shorten the time required for the medicinal liquid to reach the desired concentration, improving overall concentration efficiency and effectively reducing energy consumption per unit output. Furthermore, the steam collection device is connected to the liquid chamber 11, enabling timely and sealed collection of water vapor generated during evaporation. This vapor is then treated through condensation and other methods, effectively preventing large amounts of high-temperature, high-humidity steam from spreading into the production workshop. This fundamentally solves the problem of a hot and humid workshop environment during traditional jacketed kettle concentration processes, significantly improving the operating environment, reducing the risk of microbial growth, and making the production environment easier to control and meet the stringent requirements of Good Manufacturing Practices (GMP) for temperature, humidity, cleanliness, and prevention of cross-contamination.

[0041] like Figure 1 As shown, in this embodiment, the heating device 2 is also connected to a circulating pump 5, and the heating device 2, circulating pump 5, and concentration pot 1 are connected by a circulating pipeline, allowing the heating medium to circulate between the heating device 2, circulating pump 5, and concentration pot 1 along the circulating pipeline. This circulating flow enhances the convective heat transfer effect, effectively disrupts the temperature boundary layer of the heating medium within the jacketed cavity 12, ensures a more uniform distribution of the heating medium within the jacketed cavity 12, and significantly reduces the temperature gradient. This results in a more uniform and stable transfer of heat to the liquid in the liquid chamber 11, fundamentally avoiding the problems of local overheating or uneven heat distribution caused by natural convection in traditional jacketed pots, further improving the overall thermal efficiency and concentration uniformity of the system. Simultaneously, operators can more precisely and dynamically control the rate of heat input to the liquid by adjusting the flow rate of the circulating pump 5 or the power of the heating device 2, thereby achieving refined and automated management of the concentration process (such as evaporation rate and liquid temperature), ensuring the stability and reproducibility of process conditions.

[0042] Optionally, a buffer tank (not shown in the figure) is also connected to the circulation pipeline. The buffer tank can absorb the increased volume due to the expansion of the medium or replenish the decreased volume due to contraction, thereby maintaining the relative stability of the heating medium pressure in the system and preventing the pipeline, circulation pump 5, and other structures from being impacted or damaged by drastic pressure fluctuations. Preferably, the buffer tank is connected in series in the circulation pipeline, and the heating medium can flow into the buffer tank and the jacketed cavity 12 in sequence. The buffer tank has a viewing window structure, which allows the operator to easily observe the liquid level in the buffer tank and thus detect the operating status of the system.

[0043] Continue to refer to Figure 1 As shown, the liquid chamber 11, steam collection device, and negative pressure device are sequentially connected. Driven by the negative pressure device, the gas in the liquid chamber 11 flows along the path of the liquid chamber 11, the steam collection device, and the negative pressure device. During concentration, the suction of the negative pressure device not only reduces the gas pressure in the liquid chamber 11, thereby lowering the boiling temperature of the liquid and protecting the heat-sensitive components, but also provides power for the steam to flow into the steam collection device. This overcomes the flow resistance of the steam in the pipeline, ensuring that even at high evaporation rates, the steam can be quickly and efficiently removed from the liquid chamber 11, preventing steam accumulation in the pot that could lead to increased pressure (affecting the boiling point) or backflow risk. The steam collection device collects and processes the high-temperature steam to avoid negatively impacting the negative pressure device. Optionally, an electromagnetic switch valve 6 is connected between the steam collection device and the concentration pot 1.

[0044] Specifically, the steam collection device includes a condenser 31 and a liquid receiver 32. The condenser 31 is connected to one end of the liquid receiver 32 near the liquid chamber 11, and the other end of the liquid receiver 32 is connected to the negative pressure device. The condenser 31 is connected to a cold water supply pipe 311. When cold water flows into the condenser 31, it absorbs the heat of the gas passing through the condenser 31, thereby condensing the steam into condensate, reducing the gas temperature, and realizing the recovery and utilization of heat. The liquid receiver 32 is used to store the condensate, preventing the condensate from flowing into the negative pressure device and causing negative effects, and can centrally discharge the condensate.

[0045] Preferably, such as Figure 1 As shown, the liquid reservoir 32 has a first inlet 321 and a first outlet 322 at its top, and a second outlet 323 at its bottom. The condenser 31 is connected to the first inlet 321, and the negative pressure device is connected to the first outlet 322. The second outlet 323 serves as a drain outlet to discharge the condensate. Because both the first inlet 321 and the first outlet 322 are located at the top of the liquid reservoir 32, condensate will not enter the first outlet 322 under gravity, thus preventing condensate from flowing into the negative pressure device. Optionally, an electromagnetic switch valve 6 is provided at the second outlet 323 to control the timing of condensate discharge.

[0046] Preferably, a second inlet 324 is provided at the top of the liquid reservoir 32, and the second inlet 324 is connected to a compressed air supply pipe 7. The compressed air supply pipe 7 can supply compressed air to the liquid reservoir 32, thereby increasing the air pressure in the liquid reservoir 32 and quickly discharging the condensate. Optionally, an electromagnetic switch valve 6 is also provided at the compressed air supply pipe 7 to control the timing of compressed air supply.

[0047] Furthermore, the negative pressure device includes a vacuum pump 41 and a one-way valve 42, with the one-way valve 42 connected between the vacuum pump 41 and the first outlet 322. The one-way valve 42 is used to prevent gas from flowing from the negative pressure device to the first outlet 322, thereby maintaining a negative pressure environment when the negative pressure device is working, and realizing the extraction of gas from the liquid chamber 11.

[0048] Continue to refer to Figure 1 As shown, in this embodiment, the jacketed cavity 12 is connected to a temperature sensor 13, which is signal-connected to the heating device 2. By detecting the temperature inside the jacketed cavity 12 through the temperature sensor 13, closed-loop temperature control can be achieved with the heating device 2, ensuring that the actual temperature inside the jacketed cavity 12 remains consistent with the optimal process temperature. This helps protect the active pharmaceutical ingredients and reduce energy consumption. Furthermore, a level detector 18 is installed at the lid of the concentration pot 1, and a liquid discharge pipe 14 is connected to the liquid discharge chamber 11. An electromagnetic switch valve 6 is installed in the liquid discharge pipe 14, and the level detector 18 and the electromagnetic switch valve 6 are signal-connected. When the level detector 18 detects that the liquid has been concentrated to a preset volume, the liquid can be automatically discharged by opening the electromagnetic switch valve 6, thus facilitating automated liquid concentration. Optionally, the jacketed cavity 12 is also connected to a medium discharge pipe 15, which is also equipped with an electromagnetic switch valve 6.

[0049] Furthermore, in this embodiment, the concentrator 1 is connected to a hot water supply pipe 16, which is used to inject hot water into the liquid chamber 11, thereby achieving the effect of cleaning the liquid chamber 11. Optionally, the concentrator 1 is connected to a stirrer, which can stir the liquid in the liquid chamber 11. During liquid concentration, the stirrer can stir the liquid, which helps to improve the temperature uniformity of the liquid, avoid local overheating, protect the active ingredients, and improve the evaporation and concentration efficiency. During cleaning, the stirrer can promote the flow of hot water in the liquid chamber 11, thereby improving the cleaning effect.

[0050] Optionally, the liquid medicine chamber 11 is also connected to a negative pressure suction pipe 17, which is equipped with an electromagnetic switch valve 6. The liquid medicine to be concentrated can flow into the liquid medicine chamber 11 through the negative pressure suction pipe 17 under the drive of negative pressure, and the aforementioned negative pressure device can generate negative pressure to achieve the suction of the liquid medicine.

[0051] When using the above-mentioned drug concentration system, water can be selected as the heating medium, and the heating temperature range of the heating device 2 can be set between 40 and 100 degrees Celsius. The temperature sensor 13 can detect the actual temperature inside the jacket cavity 12. When the actual temperature is lower than the set heating temperature range, the heating device 2 will start heating. When the actual temperature reaches the set heating temperature range, the heating device 2 will stop heating.

[0052] During the concentration of the medicinal solution, the solution can be added to the solution chamber 11 manually or extracted from other containers using a negative pressure device and a negative pressure suction pipe 17. Once the solution chamber 11 contains sufficient solution, the electromagnetic switch valve 6 of the negative pressure suction pipe 17 is closed. The negative pressure device continues to operate, continuously extracting gas from the solution chamber 11 via a steam collection device to reduce the gas pressure within the chamber. When the gas pressure in the solution chamber 11 reaches approximately 0.09 MPa, the boiling point of the solution decreases to 40-60°C. At this point, the heating medium continuously heats the solution, causing it to boil and evaporate. During evaporation, the stirrer continuously agitates the solution to promote its uniformity. The steam generated during evaporation flows into the condenser 31 under the influence of negative pressure, forming condensate, which then flows into the storage tank 32. When the condensate in the storage tank 32 reaches a certain height, affecting the negative pressure, it is discharged through the drain outlet.

[0053] During the concentration process, the liquid level detector 18 measures the height of the liquid to determine its volume. Once the volume reaches a set value, the negative pressure device stops operating. At this point, compressed air is supplied through the compressed air supply pipe 7 to restore the air pressure inside the liquid chamber 11. The liquid is then discharged through the liquid discharge pipe 14. After discharge, the liquid chamber 11 is cleaned by spraying and stirring hot water. It is understood that by using the temperature sensor 13 and the liquid level detector 18, along with the control of the negative pressure device and various solenoid valves 6, an automated liquid concentration process can be achieved, greatly improving production efficiency, enabling unmanned operation, and ensuring standardized operation and efficacy.

[0054] In the description of this specification, references to terms such as "some embodiments," "other embodiments," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0055] Obviously, the above embodiments of this utility model are merely examples for clearly illustrating the present utility model, and are not intended to limit the implementation of the present utility model. Those skilled in the art can make various obvious changes, readjustments, and substitutions without departing from the protection scope of this utility model. It is neither necessary nor possible to exhaustively describe all embodiments here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this utility model should be included within the protection scope of the claims of this utility model.

Claims

1. A drug concentration system, characterized in that, include: A concentration pot (1) has a jacketed cavity (12) and a liquid medicine cavity (11), which are isolated from each other and thermally connected. Heating device (2), the heating device (2) is located outside the concentration pot (1) and communicates with the jacket cavity (12), the heating medium can circulate between the heating device (2) and the jacket cavity (12), the heating medium can absorb heat when flowing through the heating device (2) and release heat to the liquid cavity (11) when flowing through the jacket cavity (12); A negative pressure device is provided, which is connected to the liquid medicine chamber (11) and can reduce the air pressure in the liquid medicine chamber (11); A steam collection device is provided, which is connected to the liquid medicine chamber (11) and is capable of collecting steam in the liquid medicine chamber (11).

2. The drug concentration system according to claim 1, characterized in that, The heating device (2) is also connected to a circulation pump (5), which is used to drive the heating medium to circulate between the heating device (2) and the interlayer cavity (12).

3. The drug concentration system according to claim 2, characterized in that, A buffer tank is connected between the heating device (2) and the concentration pot (1), and the heating medium can flow into the buffer tank and the jacket cavity (12) in sequence.

4. The drug concentration system according to claim 1, characterized in that, The liquid chamber (11), the steam collection device, and the negative pressure device are connected in sequence.

5. The drug concentration system according to claim 4, characterized in that, The steam collection device includes a condenser (31) and a liquid storage tank (32). The condenser (31) is connected to one end of the liquid storage tank (32) near the liquid chamber (11). The condenser (31) can condense the steam into condensate. The liquid storage tank (32) is used to store the condensate and discharge it in a centralized manner.

6. The drug concentration system according to claim 5, characterized in that, The top of the liquid reservoir (32) is provided with a first inlet (321) and a first outlet (322), and the bottom of the liquid reservoir (32) is provided with a second outlet (323). The condenser (31) is connected to the first inlet (321), the negative pressure device is connected to the first outlet (322), and the second outlet (323) is configured as a drain outlet.

7. The drug concentration system according to claim 6, characterized in that, The top of the reservoir (32) is provided with a second inlet (324), and the second inlet (324) is connected to a compressed air supply pipe (7).

8. The drug concentration system according to claim 6, characterized in that, A one-way valve (42) is connected between the negative pressure device and the first outlet (322), and the one-way valve (42) is used to prevent gas from flowing from the negative pressure device to the first outlet (322).

9. The drug concentration system according to claim 1, characterized in that, The liquid chamber (11) is connected to a liquid discharge pipe (14), the liquid discharge pipe (14) is equipped with an electromagnetic switch valve (6), the concentration pot (1) is equipped with a liquid level detector (18), and the liquid level detector (18) and the electromagnetic switch valve (6) are connected by a signal; and / or, The interlayer cavity (12) is connected to a temperature sensor (13), and the temperature sensor (13) is signal-connected to the heating device (2).

10. The drug concentration system according to claim 1, characterized in that, The concentration vessel (1) is connected to a stirrer, which is capable of stirring in the liquid chamber (11); and / or, The concentration pot (1) is connected to a hot water supply pipe (16), which is used to inject hot water into the liquid chamber (11).

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