A device for precipitating and filtering crude heparin sodium

Abstract

The utility model belongs to the field of filter equipment, concretely relates to a special device for heparin sodium crude product precipitation and filtration, including the bottom plate, the top of bottom plate is connected with the box body of sliding, the top of bottom plate and located the right side fixed installation of box body has reciprocating cylinder, the output of reciprocating cylinder is connected with box body fixedly, the inside of box body is connected with a plurality of support frame of even distribution of sliding sleeve, the inside of each support frame is provided with screen cloth, the size of a plurality of screen cloth's screen cloth is reduced gradually from top to bottom. The utility model discloses the effect of the support plate design, can support the mixed liquid and can carry out the precipitation to material, and under the action of electric push rod can drive the filter screen to move down, solid thing cannot pass through the filter screen, and the liquid will pass through the filter screen, at this moment, the effect of water pump can be extracted and discharged to the liquid, can reach the purpose of the rapid precipitation of material, improves work efficiency.

Description

Technical Field

[0001] This utility model relates to the field of filtration device technology, specifically a special device for the precipitation and filtration of crude heparin sodium. Background Technology

[0002] The dedicated equipment for precipitation and filtration of crude heparin sodium is a key piece of equipment in the production of heparin sodium in the biopharmaceutical industry. It is specifically used to separate solid impurities and precipitates from the heparin sodium extract, efficiently obtain pre-purified crude heparin sodium, and lay a solid foundation for subsequent refining processes.

[0003] Utility model patent CN214436750U discloses a heparin sodium precipitation filter tank, comprising a precipitation separation tank and a storage tank. A feeding pipe and a drain pipe are installed on the top cover of the precipitation separation tank. A stirring motor is installed in the middle of the top cover, and a stirring mechanism is connected to the rotating shaft of the stirring motor. An observation window is provided on the side wall of the precipitation separation tank. The stirring mechanism includes a stirring shaft and a connecting block located at the bottom of the stirring shaft. Three downward-sloping connecting rods are provided on the connecting block, and stirring rods are hinged to the connecting rods. A filter head is installed inside the precipitation separation tank. The filter head is connected to the end of the drain pipe inside the precipitation separation tank via an elastic bellows, and the filter head is connected to a lifting mechanism. This utility model, by designing the precipitation separation tank as a tank body and a top cover, facilitates the inspection and processing of the precipitation separation tank. The lifting mechanism on the top cover drives a pull rod to move the filter head and the elastic bellows up and down, thereby solving the problem of wastewater discharge from the precipitation separation tank.

[0004] In the aforementioned prior art, the sedimentation efficiency of solids in the mixed liquid is low during device use, which affects working efficiency. Furthermore, it is inconvenient to perform multi-stage filtration and sieving of the sediment, and difficult to recover solids of different particle sizes. Therefore, improvements are needed. Utility Model Content

[0005] The purpose of this invention is to provide a special device for the precipitation and filtration of crude heparin sodium, which solves the problem of low precipitation efficiency of solids and the problem of inconvenience in multi-stage filtration and screening of precipitates.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a special device for the precipitation and filtration of crude heparin sodium, comprising a base plate, a housing slidably connected to the top of the base plate, a reciprocating cylinder fixedly installed on the top of the base plate and on the right side of the housing, the output end of the reciprocating cylinder being fixedly connected to the housing, multiple evenly distributed support frames slidably fitted inside the housing, each support frame having a screen inside, the screen aperture size of the multiple screens decreasing from top to bottom, multiple evenly distributed support rods fixedly connected to both the left and right ends of the housing, a cylinder fixedly connected to the multiple support rods, a mounting base fixedly installed on the right end of the cylinder, a motor fixedly installed on the top of the mounting base, the output end of the motor being rotatably connected to the cylinder, a partition fixedly connected to the left end of the motor output end, the partition being rotatably connected to the cylinder, a precipitation mechanism being provided on the cylinder, and a connecting mechanism being provided on the support frames.

[0007] Preferably, multiple guide rods are fixedly connected to both the left and right ends of the housing, and a guide sleeve is slidably sleeved on the outer side of each guide rod, with the guide sleeve fixedly installed on the top of the base plate. By designing the cooperation between the guide rods and the guide sleeves, the movement of the housing can be guided.

[0008] Preferably, the sedimentation mechanism includes fixed rods, with multiple fixed rods fixedly connected to the outer side of the cylinder. A top plate is fixedly connected to the top of the multiple fixed rods, and an electric push rod is fixedly installed on the top of the top plate. The output end of the electric push rod is slidably connected to the top plate, and a support plate is fixedly connected to the lower end of the output end of the electric push rod. A connecting rod is fixedly connected to the outer side of the support plate, and a connecting ring is fixedly connected to the other end of the connecting rod. A filter screen is disposed inside the connecting ring. By designing the sedimentation mechanism, solids can be separated by sedimentation.

[0009] Preferably, a water pump is fixedly installed on the top of the support plate, and a water pump pipe is provided at the bottom of the water pump. The water pump pipe passes through the support plate and is fixedly connected to the support plate. By designing the water pump, liquid can be pumped out.

[0010] Preferably, the connecting mechanism includes a connecting plate, with a connecting plate fixedly connected to the front end of each support frame. The connecting plate is slidably connected to the housing. A pull rod is fixedly connected to the front end of each connecting plate. Two symmetrically distributed support blocks are slidably connected to the bottom of each support frame. The support blocks are fixedly connected to the inner sidewall of the housing. A sliding rod is slidably fitted inside the support block. A clamping block is fixedly connected to the top of the sliding rod. The clamping block is slidably connected to the support block. A spring block, made of high-elasticity rubber, is fixedly connected to the lower end of the clamping block. The spring block is fixedly connected to the support block. A retaining ball is movably fitted inside the clamping block. The retaining ball is movably connected to both the support block and the support frame. This connecting mechanism facilitates the removal of the support frame from the housing.

[0011] Preferably, a spring is provided on the outer side of the slide rod, one end of the spring is fixedly connected to the abutment block, and the other end of the spring is fixedly connected to the support block. By designing the spring, the elastic force of the spring can be applied to the abutment block.

[0012] Preferably, the bottom of the support frame has multiple symmetrically and evenly distributed slots, and each slot has a retaining ball that is movably fitted inside. By designing multiple slots and retaining balls to engage and cooperate, the support frame can be limited in position.

[0013] Compared with the prior art, the beneficial effects of this utility model are as follows: 1. This utility model uses a support plate to support the mixture and allow the material to settle. Under the action of the electric push rod, the filter screen can be moved down, so that solids cannot pass through the filter screen, while liquids will pass through the filter screen. At this time, with the action of the water pump, the liquid can be extracted and discharged, which can achieve the purpose of rapid sedimentation of materials and improve work efficiency.

[0014] 2. This utility model, through the design of multiple screens, can perform multi-stage screening and filtration of precipitated solids, thereby improving the filtration effect. The insertion of the locking ball and the locking groove can limit the support frame, achieving the purpose of installing and using the screen and the box. When the pull rod is pulled outward, the locking ball and the locking groove can be separated, and the support frame can be pulled out from the inside of the box, which facilitates the collection of filtered and screened materials and the replacement of screens with different aperture sizes. Attached Figure Description

[0015] Figure 1 This is a three-dimensional view of the overall structure of this utility model; Figure 2 This utility model Figure 1 A three-dimensional sectional view of the cylinder; Figure 3 This utility model Figure 1 A three-dimensional sectional view of the box; Figure 4 This utility model Figure 3 Enlarged view of point A.

[0016] In the diagram: 1. Base plate; 2. Box body; 3. Reciprocating cylinder; 4. Guide rod; 5. Guide sleeve; 6. Support frame; 7. Screen; 8. Sedimentation mechanism; 9. Connecting mechanism; 10. Support rod; 11. Cylinder; 12. Motor; 13. Partition plate; 14. Mounting base; 81. Fixed rod; 82. Top plate; 83. Electric push rod; 84. Support plate; 85. Connecting rod; 86. Connecting ring; 87. Filter screen; 88. Water pump; 89. Pumping pipe; 91. Connecting plate; 92. Pull rod; 93. Support block; 94. Slide rod; 95. Spring; 96. Clamping block; 97. Spring block; 98. Ball clamp; 99. Slot. Detailed Implementation

[0017] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0018] Please see Figure 1 , Figure 2 , Figure 3 A special device for the precipitation and filtration of crude heparin sodium includes a base plate 1, a housing 2 slidably connected to the top of the base plate 1, a reciprocating cylinder 3 fixedly installed on the top of the base plate 1 and on the right side of the housing 2, the output end of the reciprocating cylinder 3 being fixedly connected to the housing 2, multiple guide rods 4 fixedly connected to both ends of the housing 2, and a guide sleeve 5 slidably sleeved on the outer side of each guide rod 4, the guide sleeve 5 being fixedly installed on the top of the base plate 1. Through the design of the cooperation between the guide rods 4 and the guide sleeves 5, the movement of the housing 2 can be guided. Multiple evenly distributed support frames 6 are slidably sleeved inside the housing 2. The interior is equipped with screens 7, and the screen mesh size of multiple screens 7 decreases from top to bottom. Multiple evenly distributed support rods 10 are fixedly connected to both ends of the box body 2. The multiple support rods 10 are fixedly connected to a cylinder 11. A mounting base 14 is fixedly installed on the right end of the cylinder 11. A motor 12 is fixedly installed on the top of the mounting base 14. The output end of the motor 12 is rotatably connected to the cylinder 11. A partition 13 is fixedly connected to the left end of the output end of the motor 12. The partition 13 is rotatably connected to the cylinder 11. A sedimentation mechanism 8 is provided on the cylinder 11, and a connecting mechanism 9 is provided on the support frame 6.

[0019] Please see Figure 1 , Figure 2The sedimentation mechanism 8 includes fixed rods 81. Multiple fixed rods 81 are fixedly connected to the outside of the cylinder 11. A top plate 82 is fixedly connected to the top of the multiple fixed rods 81. An electric push rod 83 is fixedly installed on the top of the top plate 82. The output end of the electric push rod 83 is slidably connected to the top plate 82. A support plate 84 is fixedly connected to the lower end of the output end of the electric push rod 83. A connecting rod 85 is fixedly connected to the outside of the support plate 84. A connecting ring 86 is fixedly connected to the other end of the connecting rod 85. A filter screen 87 is provided inside the connecting ring 86. A water pump 88 is fixedly installed on the top of the support plate 84. A water pump pipe 89 is provided at the bottom of the water pump 88. The water pump pipe 89 passes through the support plate 84 and is fixedly connected to the support plate 84. By designing the water pump 88, liquid can be pumped out. By designing the sedimentation mechanism 8, solids can be separated by sedimentation.

[0020] Please see Figure 1 , Figure 3 , Figure 4 The connecting mechanism 9 includes a connecting plate 91. A connecting plate 91 is fixedly connected to the front end of each support frame 6, and the connecting plate 91 is slidably connected to the housing 2. A pull rod 92 is fixedly connected to the front end of each connecting plate 91. Two symmetrically distributed support blocks 93 are slidably connected to the bottom of each support frame 6. The support blocks 93 are fixedly connected to the inner wall of the housing 2. A slide rod 94 is slidably fitted inside the support block 93, and a spring 95 is provided on the outer side of the slide rod 94. One end of the spring 95 is fixedly connected to a clamping block 96, and the other end of the spring 95 is fixedly connected to the support block 93. By designing the spring 95, the elastic force of the spring 95 can act on the clamping block 96. A clamping block 96 is fixedly connected to the top of the slide rod 94. The clamping block 96 is slidably connected to the support block 93. A spring block 97 is fixedly connected to the lower end of the clamping block 96. The spring block 97 is made of high-elastic rubber and is fixedly connected to the support block 93. A retaining ball 98 is movably sleeved inside the clamping block 96. The retaining ball 98 is movably connected to the support block 93 and the support frame 6 respectively. The bottom of the support frame 6 has multiple symmetrical and evenly distributed slots 99. Each slot 99 has a retaining ball 98 movably sleeved inside. By designing multiple slots 99 and retaining balls 98 to fit together, the support frame 6 can be limited. By designing the connecting mechanism 9, the support frame 6 can be easily removed from the inside of the housing 2.

[0021] The specific implementation process of this utility model is as follows: In use, the mixture to be settled is first injected into the inside of the cylinder 11. The mixture settles on the partition plate 13. Then, the electric push rod 83 is started. The output end of the electric push rod 83 drives the support plate 84 to move down. The support plate 84 drives the connecting rod 85 and the connecting ring 86 to move down, so that the filter screen 87 comes into contact with the solids inside the mixture. The solids cannot pass through the filter screen 87, while the liquid will pass through the filter screen 87. At this time, the water pump 88 pumps the liquid out through the water pipe 89, which can achieve the purpose of rapid sedimentation of materials and improve work efficiency.

[0022] After the solids have settled, the motor 12 is started. The output of the motor 12 drives the partition 13 to flip. At this time, the solids will fall into the interior of the box 2. Under the action of multiple screens 7, the material can be filtered in multiple stages, which can improve the filtration effect. During screening and filtration, the output of the reciprocating cylinder 3 drives the box 2 to move horizontally back and forth. The box 2 drives the guide rod 4 to slide along the guide sleeve 5, which can realize the horizontal shaking of the screens 7 and accelerate the filtration and screening efficiency of the material.

[0023] When the screen 7 needs to be disassembled, pull the lever 92 outwards. The lever 92 moves the connecting plate 91, which in turn moves the support frame 6. The support frame 6 slides along the support block 93. The arc surface of the slot 99 at the bottom of the support frame 6 will press and push the ball 98, causing it to roll downwards. The ball 98 will push the clamping block 96 downwards, which will press down the spring block 97. At the same time, the clamping block 96 will move the sliding rod 94 downwards, and the clamping block 96 will press down the spring 95, which will separate the ball 98 from the slot 99. Then the support frame 6 can be directly pulled out from the inside of the box 2, which is convenient for collecting filtered and screened materials and for replacing screens 7 with different apertures.

[0024] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A special device for precipitation and filtration of crude heparin sodium, comprising a base plate (1), characterized in that: A box body (2) is slidably connected to the top of the base plate (1). A reciprocating cylinder (3) is fixedly installed on the top of the base plate (1) and on the right side of the box body (2). The output end of the reciprocating cylinder (3) is fixedly connected to the box body (2). Multiple evenly distributed support frames (6) are slidably fitted inside the box body (2). Each support frame (6) is provided with a screen (7). The size of the screen holes of the multiple screens (7) decreases from top to bottom. Multiple evenly distributed support rods (10) are fixedly connected to both the left and right ends of the box body (2). A cylinder (11) is fixedly connected to multiple support rods (10). A mounting base (14) is fixedly installed on the right end of the cylinder (11). A motor (12) is fixedly installed on the top of the mounting base (14). The output end of the motor (12) is rotatably connected to the cylinder (11). A partition (13) is fixedly connected to the left end of the output end of the motor (12). The partition (13) is rotatably connected to the cylinder (11). A sedimentation mechanism (8) is provided on the cylinder (11). A connecting mechanism (9) is provided on the support frame (6).

2. The device for precipitation and filtration of crude heparin sodium according to claim 1, characterized in that: Multiple guide rods (4) are fixedly connected to both the left and right ends of the box (2). Each guide rod (4) is slidably sleeved with a guide sleeve (5) on its outer side. The guide sleeve (5) is fixedly installed on the top of the base plate (1).

3. The device for precipitation and filtration of crude heparin sodium according to claim 1, characterized in that: The sedimentation mechanism (8) includes a fixed rod (81). Multiple fixed rods (81) are fixedly connected to the outside of the cylinder (11). A top plate (82) is fixedly connected to the top of the multiple fixed rods (81). An electric push rod (83) is fixedly installed on the top of the top plate (82). The output end of the electric push rod (83) is slidably connected to the top plate (82). A support plate (84) is fixedly connected to the lower end of the output end of the electric push rod (83). A connecting rod (85) is fixedly connected to the outside of the support plate (84). A connecting ring (86) is fixedly connected to the other end of the connecting rod (85). A filter screen (87) is provided inside the connecting ring (86).

4. The device for precipitation and filtration of crude heparin sodium according to claim 3, characterized in that: A water pump (88) is fixedly installed on the top of the support plate (84), and a water pump pipe (89) is provided at the bottom of the water pump (88). The water pump pipe (89) passes through the support plate (84) and is fixedly connected to the support plate (84).

5. The device for precipitation and filtration of crude heparin sodium according to claim 1, characterized in that: The connecting mechanism (9) includes a connecting plate (91). The front end of each support frame (6) is fixedly connected to the connecting plate (91). The connecting plate (91) is slidably connected to the box body (2). The front end of each connecting plate (91) is fixedly connected to a pull rod (92). The bottom of each support frame (6) is slidably connected to two symmetrically distributed support blocks (93). The support blocks (93) are fixedly connected to the inner sidewall of the box body (2). The inside of the support blocks (93) is slidably sleeved. There is a sliding rod (94), and a clamping block (96) is fixedly connected to the top of the sliding rod (94). The clamping block (96) is slidably connected to the support block (93). A spring block (97) is fixedly connected to the lower end of the clamping block (96). The spring block (97) is made of high elastic rubber. The spring block (97) is fixedly connected to the support block (93). A retaining ball (98) is movably sleeved inside the clamping block (96). The retaining ball (98) is movably connected to the support block (93) and the support frame (6) respectively.

6. The device for precipitation and filtration of crude heparin sodium according to claim 5, characterized in that: A spring (95) is provided on the outside of the slide bar (94). One end of the spring (95) is fixedly connected to the abutment block (96), and the other end of the spring (95) is fixedly connected to the support block (93).

7. The device for precipitation and filtration of crude heparin sodium according to claim 1, characterized in that: The bottom of the support frame (6) is provided with a plurality of symmetrical and evenly distributed slots (99), and each slot (99) is movably fitted with a ball (98).

Images