reaction tube

Abstract

The utility model discloses a kind of reaction tubes, including shape is at least one end opening outer tube and inner tube, the inner tube is set in the outer tube, the top of the inner tube is outwardly provided with flange, the flange is tightly fitted between the inner wall of the outer tube, so that the outer wall of the inner tube and the inner wall of the outer tube are sealed to form reaction cavity, reaction beads are stored in the reaction cavity.The utility model has the beneficial effects as follows: outer tube and inner tube jointly constitute pipe body, the inner tube is set in the outer tube, and the flange of the top of the inner tube is tightly fitted between the inside of the outside, so as to form relatively airtight space in reaction cavity, the sealing effect is better, air is difficult to enter, even if reaction tube is placed in air for a long time, reaction beads in reaction cavity are also difficult to contact with air, so as to reduce the possibility that detection result is influenced.

Description

Technical Field

[0001] This utility model belongs to the field of biomedical detection technology, and in particular relates to a reaction tube for detection. Background Technology

[0002] In the field of biomedical testing, reaction tubes are crucial experimental consumables used for storing, mixing, and reacting reagents, and are widely used in PCR amplification, fluorescence detection, enzyme-linked immunosorbent assay (ELISA), and other experimental scenarios. Reaction tubes are typically sealed in packaging. They are removed from the packaging before use, reagents are injected, the reaction proceeds, and the resulting reagents are analyzed. However, if reaction tubes are not used for an extended period after being removed from the packaging, air can enter the tube and react with the reaction beads inside. This can affect the test results when the tube is subsequently used for testing. Utility Model Content

[0003] The purpose of this invention is to solve the aforementioned problems in the prior art and to provide a reaction tube.

[0004] The objective of this utility model is achieved through the following technical solution: A reaction tube includes an outer tube and an inner tube, both of which are open at least one end. The inner tube is disposed inside the outer tube. The top of the inner tube has an outwardly extending flange. The flange is tightly fitted with the inner wall of the outer tube, thereby sealing the outer wall of the inner tube and the inner wall of the outer tube to form a reaction chamber. The reaction chamber contains reaction microspheres.

[0005] Preferably, the inner tube includes a main body and a connecting portion connecting the main body and the flange; the outer wall of the main body and the outer wall of the connecting portion are stepped, the outer diameter of the connecting portion is approximately equal to the inner diameter of the outer tube, and the reaction chamber is formed by the inner wall of the outer tube and the outer wall of the main body.

[0006] Preferably, the distance between the outer wall of the main body and the inner wall of the outer tube is less than the diameter of the reaction sphere.

[0007] Preferably, the top of the inner tube is lower than the top of the outer tube, and the inner wall of the outer tube is provided with a limiting ring, which abuts against the top of the inner tube to lock the inner tube.

[0008] Preferably, a notch is provided on one side of the outer wall of the flange, the notch is connected to the reaction chamber, and the width of the notch is greater than the width of the limiting ring.

[0009] Preferably, the inner tube has a flow guiding cavity for adding reagents and for guiding the flow, and the flow guiding cavity is funnel-shaped.

[0010] Preferably, the inner tube is integrally formed, and the bottom of the inner tube may optionally have a self-closing micropore in a free state.

[0011] Preferably, the outer tube is integrally formed, and the thickness of the bottom of the outer tube can be selectively less than the thickness of the sidewall of the outer tube, so that the bottom of the outer tube is suitable for being punctured.

[0012] Preferably, it has a sealing cap, which is sealed and fixed to the outer tube by a threaded connection.

[0013] Preferably, a sealing device is provided between the opening of the outer tube and the sealing cap, and the sealing device is in the form of an inverted convex shape, with its small diameter portion located on the inner wall of the outer tube; the sealing device and the sealing cap are separate components or an integral structure.

[0014] The advantages of this utility model's technical solution are mainly reflected in: The tube structure is composed of an outer tube and an inner tube. The inner tube is placed inside the outer tube, and the flange at the top of the inner tube fits tightly with the inner part of the outer tube, thus forming a roughly sealed space in the reaction chamber of the tube. The sealing effect is good, and air is difficult to enter. Even if the reaction tube is placed in the air for a long time, the reaction ball in the reaction chamber is unlikely to come into contact with the air, thereby reducing the possibility of the test results being affected.

[0015] By placing an inner tube inside the outer tube, the space of the reaction chamber is reduced, thus minimizing the storage space for the reaction balls. This reduces the likelihood of the reaction balls being suspended in corners due to static electricity caused by shaking during transportation and handling of the reaction tube. As a result, the reaction balls are located at the bottom of the reaction tube and can fully react with the reagents, ensuring accurate detection.

[0016] The inner tube's flow guide cavity is funnel-shaped, which facilitates the guidance of the reagent gun for reagent dispensing and guides the injected reagent, ensuring that all the reagent is injected into the reaction chamber and reacts fully with the reaction beads in the reaction chamber. Attached Figure Description

[0017] Figure 1 : A perspective view of a preferred embodiment of the present invention; Figure 2 : Exploded view of a preferred embodiment of this utility model; Figure 3 : A cross-sectional view of a preferred embodiment of the present invention. Detailed Implementation

[0018] The purpose, advantages, and features of this utility model will be illustrated and explained through the following non-limiting description of preferred embodiments. These embodiments are merely typical examples of applying the technical solutions of this utility model, and all technical solutions formed by equivalent substitutions or equivalent transformations fall within the scope of protection claimed by this utility model.

[0019] like Figures 1 to 3 As shown, this utility model discloses a reaction tube, comprising an outer tube 1 and an inner tube 2, both with at least an open top. The outer tube 1 and the inner tube 2 together constitute the tube body, with the inner tube 2 disposed within the outer tube 1. A reaction chamber 102 is formed within the tube body, and reaction microspheres 11 are placed within the reaction chamber 102. Specifically, the top of the inner tube 2 has an outwardly extending flange 20, which is tightly fitted with the inner wall of the outer tube 1, sealing the outer wall of the inner tube 2 with the inner wall of the outer tube 1 to form the reaction chamber 102. The tube body of this utility model is sealed in packaging before use and removed from the packaging when in use. Because the flange 20 of the inner tube 2 is tightly fitted with the inner wall of the outer tube 1, i.e., the inner wall of the outer tube 1 abuts against the outer wall of the inner tube 2 (the outer wall of the flange 20 portion), the reaction chamber 102 becomes a substantially sealed space, making it difficult for air to enter. Therefore, the reaction tube of this invention has a good sealing effect. Even if it is placed in the air for a long time, the reaction ball 11 in the reaction chamber 102 is unlikely to come into contact with the air, thereby reducing the possibility of the test results being affected.

[0020] Furthermore, an inner tube 2 is provided inside the outer tube 1, which makes the space of the reaction chamber 102 smaller, restricting the degree of freedom of movement of the reaction ball 11 inside the reaction chamber 102. This reduces the situation where the reaction ball 11 is suspended in a corner due to static electricity generated by shaking during transportation and handling, so that the reaction ball 11 is located at the bottom of the reaction tube and can fully react with the reagent, ensuring the accuracy of detection.

[0021] Specific combination Figure 2 and Figure 3 As shown, the inner tube 2 includes a main body portion 21 and a connecting portion 22 connecting the main body portion 21 and the flange 20. The outer wall of the main body portion 21 and the outer wall of the connecting portion 22 are stepped, and the outer diameter of the connecting portion 22 is approximately equal to the inner diameter of the outer tube 1. The reaction chamber 102 is formed by the inner wall of the outer tube 1 and the outer wall of the main body portion 21. Furthermore, the distance between the outer wall of the main body portion 21 and the inner wall of the outer tube 1 is less than the diameter of the reaction spheres 11, thereby ensuring that the reaction spheres 11 are all located at the bottom of the reaction tube and will not be suspended in a corner of a side wall due to shaking or friction.

[0022] Furthermore, the top of the inner tube 2 is lower than the top of the outer tube 1, and a limiting ring 14 is provided on the inner wall of the outer tube 1, which abuts against the top of the inner tube 2. The limiting ring 14 protrudes from the inner wall of the outer tube 1 and limits the inner tube 2, effectively preventing the inner tube 2 from falling out of the outer tube 1.

[0023] In this preferred embodiment, a notch 220 is also provided on one side of the outer wall of the flange 20. The notch 220 is connected to the reaction chamber 102, and the width of the notch 220 is greater than the width of the limiting ring 14. The notch 220 provides a certain deformation space for the inner tube 2 during assembly, enabling rapid assembly of the inner tube 2. Furthermore, when reagents are injected into the reaction chamber 102, the pressure inside the outer tube 1 can be released outward through the notch 220, thereby ensuring normal reagent injection. Of course, the notch 220 is not large; only its width needs to be greater than the width of the limiting ring 14. And since it is only located on one side of the outer wall of the flange 20, airflow remains relatively small. Even if the reaction tube is placed in the air for a long time, the incoming air is unlikely to cause the reaction beads 11 in the reaction tube to produce a significant reaction, so it will not affect the detection results.

[0024] The inner tube 2 has a flow channel 201 for injecting reagents. When testing is to be performed, the bottom of the flow channel 201 (i.e., the bottom 23 of the inner tube) is punctured by the tip of a reagent gun, and the reagent is injected into the reaction chamber 102. Preferably, the inner tube 2 is integrally formed, and the bottom 23 of the inner tube may optionally have a self-sealing micropore in a free state, making the bottom of the inner tube 2 more suitable for puncture. Of course, those skilled in the art will know that adding a sealing film to the bottom opening of the inner tube 2 is also an equivalent variation of this preferred embodiment.

[0025] In this preferred embodiment, the flow guiding cavity 201 is funnel-shaped, which facilitates the guidance of the reagent gun for reagent dispensing and also guides the injected reagent, ensuring that all the reagent is injected into the reaction chamber 102 and reacts fully with the reaction pellets 11 in the outer tube 1 to form an amplification product. This amplification product can ultimately flow out to the detection device by puncturing the bottom of the outer tube 1 for detection. Furthermore, the width of the bottom of the flow guiding cavity 201 is smaller than the diameter of the reagent gun, thus ensuring that only the needle of the reagent gun can puncture the bottom of the flow guiding cavity 201 and enter the reaction chamber 102, while other parts cannot enter the reaction chamber 102, reducing contamination.

[0026] The outer tube 1 is integrally formed, and the thickness of the bottom of the outer tube 1 can be selectively set to be less than the thickness of the sidewall of the outer tube 1, so that the bottom of the outer tube 1 is suitable for being punctured, thereby allowing the amplified product after the reaction to flow out into another detection device. Of course, those skilled in the art will know that the scheme of adding a sealing film to the opening at the bottom of the outer tube 1 is also an equivalent variation of the preferred embodiment.

[0027] The reaction tube also has a sealing cap 3, which covers the top of the outer tube 1 and the inner tube 2, meaning the openings of the outer tube 1 and the inner tube 2 are covered by the sealing cap 3. Specifically, the outer tube 1 and the sealing cap 3 are sealed and fixed together by a threaded connection to prevent reagents from spilling out of the reaction tube. To facilitate quick installation and removal of the sealing cap 3, this invention preferably provides a set of concave and convex structures on the outer circumferential surface of the sealing cap 3 to enhance friction during operation.

[0028] Further as Figure 2 As shown, a sealing device 13, preferably a sealing ring, is provided between the opening of the outer tube 1 and the sealing cap 3. The sealing device 13 is an inverted convex shape, with its smaller diameter portion located on the inner wall of the outer tube 1. The sealing effect of the sealing device 13 further improves the sealing performance of the reaction tube. The sealing device 13 and the outer tube 1 can be two separate components, assembled together during use; or the sealing device 13 and the outer tube 1 can be integrally molded using two-color injection molding, which facilitates assembly.

[0029] This utility model has many other embodiments. All technical solutions formed by equivalent transformation or equivalent transformation fall within the protection scope of this utility model.

Claims

1. A reaction tube, characterized in that: The device includes an outer tube (1) and an inner tube (2), both of which are open at least at one end. The inner tube (2) is disposed inside the outer tube (1). The top of the inner tube (2) is provided with a flange (20) facing outward. The flange (20) and the inner wall of the outer tube (1) are tightly fitted together, so that the outer wall of the inner tube (2) and the inner wall of the outer tube (1) are sealed to form a reaction chamber (102). The reaction chamber (102) contains reaction microspheres (11).

2. The reaction tube according to claim 1, characterized in that: The inner tube (2) includes a main body (21) and a connecting part (22) connecting the main body (21) and the flange (20); the outer wall of the main body (21) and the outer wall of the connecting part (22) are stepped, the outer diameter of the connecting part (22) is equivalent to the inner diameter of the outer tube (1), and the reaction chamber (102) is formed by the inner wall of the outer tube (1) and the outer wall of the main body (21).

3. The reaction tube according to claim 2, characterized in that: The distance between the outer wall of the main body (21) and the inner wall of the outer tube (1) is less than the diameter of the reaction ball (11).

4. The reaction tube according to claim 3, characterized in that: The top of the inner tube (2) is lower than the top of the outer tube (1), and the inner wall of the outer tube (1) is provided with a limiting ring (14), which abuts against the top of the inner tube (2) to lock the inner tube (2).

5. The reaction tube according to claim 4, characterized in that: The flange (20) has a notch (220) on one side of its outer wall. The notch (220) is connected to the reaction chamber (102). The width of the notch (220) is greater than the width of the limiting ring (14).

6. The reaction tube according to claim 1, characterized in that: The inner tube (2) has a flow guide cavity (201) for adding reagents and for guiding flow. The flow guide cavity (201) is funnel-shaped.

7. The reaction tube according to claim 1, characterized in that: The inner tube (2) is integrally formed, and the bottom (23) of the inner tube (2) may optionally have a self-sealing micropore in a free state.

8. The reaction tube according to claim 1, characterized in that: The outer tube (1) is integrally formed, and the thickness of the bottom of the outer tube (1) can be selectively less than the thickness of the side wall of the outer tube (1), so that the bottom of the outer tube (1) is suitable for being punctured.

9. The reaction tube according to claim 1, characterized in that: It has a sealing cap (3), which is sealed and fixed to the outer tube (1) by a threaded connection.

10. The reaction tube according to claim 9, characterized in that: A sealing device (13) is provided between the opening of the outer tube (1) and the sealing cover (3), and the sealing device (13) is an inverted convex shape, with its small diameter part located on the inner wall of the outer tube (1); the sealing device (13) and the sealing cover (3) are separate components or an integral structure.

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