Sample container and sample analysis apparatus

CN224894204UActive Publication Date: 2026-10-27SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202522355064.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Priority Date
2024-11-05
Filing Date
2025-11-05
Publication Date
2026-10-27
Estimated Expiration
2035-11-05

AI Technical Summary

Technical Problem

[0003]目前,尿液采样通常是由病患自己取样后倒入尿管,有时候会存在病患没有盖紧瓶盖的情况,为了避免瓶盖脱落、样本泄漏等问题,尿液样本不能用常规的机械旋转、摇摆的方式混匀,只能在采样前由人工进行混匀,严重影响到尿液样本自动化检测的实现

Benefits of technology

[0010]本实施例中,通过设置缓冲腔对从第一开口向第一穿刺件溅起的样本进行缓冲,可以减少或者避免溅起的样本通过第一穿刺件的被穿刺部位溅出,从而降低污染风险。

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN224894204U_ABST
    Figure CN224894204U_ABST
Patent Text Reader

Abstract

The application discloses a sample container, which comprises a container body and a container cap. The container body has an inner cavity for storing a sample, and one end of the inner cavity forms a first opening on the container body. The container cap comprises a connecting section, a puncture section and a first puncture piece. The container cap is connected to one end of the container body through at least part of the connecting section. The first puncture piece can be punctured by a sampling component so that the sampling component extends into the inner cavity of the container body. The sampling component extending into the inner cavity can mix and stir the sample in the inner cavity. When the container cap is connected to the container body, the container cap has a buffer cavity formed between the first puncture piece and the first opening. The buffer cavity is configured to buffer the sample splashed from the first opening to the first puncture piece during the mixing and stirring process. The application can reduce or avoid the splashed sample from splashing out through the punctured part of the first puncture piece, thereby reducing the risk of pollution.
Need to check novelty before this filing date? Find Prior Art

Description

[0001] This application claims priority to an earlier application, application number 202422699104.8, filed on November 5, 2024, entitled "Sample Container". Technical Field

[0002] This invention relates to the field of medical device technology, and in particular to a sample container. Background Technology

[0003] Currently, urine samples are usually collected by the patient themselves and poured into the urine catheter. Sometimes, the patient does not tighten the cap. In order to avoid problems such as the cap falling off and sample leakage, the urine sample cannot be mixed by conventional mechanical rotation or shaking. It can only be mixed manually before sampling, which seriously affects the realization of automated urine sample testing. Utility Model Content

[0004] This application aims to address at least one of the technical problems existing in the prior art. To this end, this application proposes a sample container and sample analysis device that can reduce sample splashing during the aspiration and mixing process, thereby reducing the risk of contamination.

[0005] To achieve one of the above objectives, some embodiments of this application provide a sample container, including:

[0006] A container body having an inner cavity for storing samples, one end of which forms a first opening on the container body;

[0007] A container cap includes a connecting section and a puncture section connected to the connecting section. The container cap is connected to the end of the container body having the first opening via at least a portion of the connecting section. The container cap also includes a first puncture member connected to the puncture section. The first puncture member can be punctured to form a first puncture hole. A sampling component can be inserted into the sample in the inner cavity of the container body through the first puncture hole and can repeatedly perform the liquid aspiration operation of drawing the sample and the liquid discharge operation of discharging the sample to mix the sample in the inner cavity.

[0008] When the container cap is connected to the container body, the container cap has a buffer cavity formed between the first puncture member and the first opening. The buffer cavity is configured to buffer the sample splashed from the first opening to the first puncture member during the suction and discharge mixing process.

[0009] The sample container according to the embodiments of this application has at least the following beneficial effects:

[0010] In this embodiment, by setting a buffer cavity to buffer the sample splashed from the first opening to the first puncture member, the splashed sample can be reduced or avoided from splashing out through the punctured part of the first puncture member, thereby reducing the risk of contamination.

[0011] In other embodiments of this application, the buffer cavity is configured to buffer the sample splashed from the first opening to the first puncture member during the suction and discharge mixing process, including: the buffer cavity is configured to prevent part or all of the splashed sample from splashing out of the first puncture hole during the suction and discharge mixing process.

[0012] In other embodiments of this application, the length of the buffer cavity along the axial direction of the container body is greater than or equal to 5 mm; preferably, the length of the buffer cavity along the axial direction of the container body is greater than or equal to 15 mm; preferably, the length of the buffer cavity along the axial direction of the container body is less than or equal to 20 mm.

[0013] In other embodiments of this application, the first puncture member forms a receiving cavity with the puncture section on the side opposite to the first opening. The receiving cavity has an opening opposite to the first opening. The receiving cavity is used to receive samples separated from the sampling member. Preferably, the receiving cavity is also used to receive samples that may splash out of the first puncture hole.

[0014] In other embodiments of this application, the cross-sectional area of ​​the receiving cavity increases along the direction from the receiving cavity to the buffer cavity, and / or the cavity wall of the receiving cavity has at least one first flange extending circumferentially along the receiving cavity.

[0015] In other embodiments of this application, the container cap further includes a second puncture member connected to the puncture section. The first puncture member and the second puncture member are spaced apart along the axial direction of the container body. The second puncture member can be punctured to form a second puncture hole. The sampling component can extend into the sample in the inner cavity of the container body through the second puncture hole.

[0016] In other embodiments of this application, the second puncture member is disposed within the buffer cavity;

[0017] Alternatively, the first puncture member on the side opposite to the first opening forms a receiving cavity with the puncture section, and the second puncture member is disposed in the receiving cavity. Or, the second puncture member, the first puncture member, and the puncture section together enclose the receiving cavity, and the receiving cavity is used to receive the sample separated from the sampling member. Preferably, the receiving cavity is also used to receive the sample that may splash out of the first puncture hole and / or the sample that may splash out of the second puncture hole.

[0018] In other embodiments of this application, the puncture segment and the connecting segment are configured as an integral cylindrical structure; preferably, the container cap is threaded to the end of the container body having the first opening by at least a portion of the connecting segment, or the container cap is snapped onto the end of the container body having the first opening by at least a portion of the connecting segment.

[0019] In other embodiments of this application, the container cap further includes a flip-over connector, wherein the puncture section and the connecting section are configured as separate cylindrical structures, the puncture section is connected to the connecting section via the flip-over connector, and the puncture section can be flipped relative to the connecting section to close or open the first opening; preferably, the container cap is threadedly connected to the end of the container body having the first opening via at least a portion of the connecting section, or the container cap is snapped onto the end of the container body having the first opening via at least a portion of the connecting section; preferably, when the puncture section closes the first opening, a portion of the buffer cavity is formed within the puncture section and another portion is formed within the connecting section, or the buffer cavity is formed within the puncture section, or the buffer cavity is formed within the connecting section.

[0020] In other embodiments of this application, the puncture segment has a second flange extending inwardly along its inner circumference, and the edge of the first puncture member is connected to the second flange; preferably, the edge of the first puncture member is bonded to the second flange, or the edge of the first puncture member is welded to the second flange.

[0021] In other embodiments of this application, the first puncture element is configured as a puncture membrane; preferably, the puncture membrane is configured as a rubber membrane, silicone membrane, aluminum membrane, tin membrane or paper membrane; preferably, the thickness of the puncture membrane is 0.1 mm to 2 mm; more preferably, the thickness of the puncture membrane is 0.5 mm to 1 mm.

[0022] For one of the above purposes, some embodiments of this application provide sample containers, including:

[0023] A container body having an inner cavity for storing samples, one end of which forms a first opening on the container body;

[0024] A container cap is attached to one end of the container body having the first opening. The container cap also includes a puncture member that can be punctured to allow a sampling component to extend into the sample within the inner cavity of the container body.

[0025] The puncture member and the first opening have a splash-proof portion configured to prevent the sample splashed from the first opening from completely passing through the puncture member.

[0026] In other embodiments of this application, the splash-proof portion is configured to limit the sample splashed from the first opening from completely passing through the puncture member, including: the splash-proof portion is configured to prevent some or all of the splashed sample from splashing out of the puncture member.

[0027] In other embodiments of this application, the length of the splash-proof portion along the axial direction of the container body is greater than or equal to 5 mm; preferably, the length of the splash-proof portion along the axial direction of the container body is greater than or equal to 15 mm; preferably, the length of the splash-proof portion along the axial direction of the container body is less than or equal to 20 mm.

[0028] To achieve one of the above objectives, some embodiments of this application provide a sample container, characterized in that it includes:

[0029] A container body having an inner cavity for storing samples, one end of which forms a first opening on the container body;

[0030] A container cap includes a puncture channel and a first puncture member that forms a barrier to the puncture channel. The container cap can be connected to one end of the container body having the first opening. The first puncture member has a puncture area through which a sampling component can pass, so that the sampling component passes through the puncture area and extends into the sample in the inner cavity for suction, discharge, and mixing.

[0031] When the container cap covers the container body, the puncture channel is sealed and connected to the first opening, the first puncture member is located above the first opening, and the distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 5 mm.

[0032] The sample container according to embodiments of the present invention has at least the following beneficial effects:

[0033] In this embodiment, by setting the distance between the puncture area and the first opening along the axial direction of the container body to be greater than or equal to 5 mm, the splashed sample is reduced or avoided from splashing out through the punctured part of the first puncture member, thereby reducing the risk of contamination.

[0034] In other embodiments of this application, the distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 15 mm; preferably, the distance between the puncture area and the first opening along the axial direction of the container body is less than or equal to 20 mm.

[0035] In other embodiments of this application, the container cap includes a limiting structure for upper limit of the container body, the limiting structure being located below the first puncture member, and the distance between the limiting structure and the first puncture member along the axial direction of the container body is configured to ensure that the distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 5 mm.

[0036] In other embodiments of this application, the limiting structure includes a stepped surface. When the container cap covers the container body, the distance between the stepped surface and the first puncture member along the axial direction of the container body is greater than or equal to 5 mm. The stepped surface is located above the upper end face of the first opening, and the two abut against each other vertically.

[0037] In other embodiments of this application, the container cap includes a docking structure for connecting to the outer side wall of the container body. When the container cap covers the container body, the docking structure is located below the first puncture member. The distance between the docking structure and the first puncture member along the axial direction of the container body is greater than 5 mm, so as to ensure that the distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 5 mm.

[0038] In other embodiments of this application, the mating structure is a threaded structure, a snap-fit ​​structure, an adhesive structure, an elastic fit structure, or a tight fit structure.

[0039] In other embodiments of this application, the puncture channel has a receiving cavity located on the upper side of the first puncture member, the receiving cavity having an opening facing away from the first opening, the receiving cavity being used to receive samples separated from the sampling member, and / or to receive samples splashed from the puncture area.

[0040] In other embodiments of this application, the cross-sectional area of ​​the receiving cavity is increased along the direction from the opening to the first opening to prevent the sample inside the receiving cavity from flowing out of the opening;

[0041] And / or, the cavity wall of the receiving cavity has at least one first flange extending circumferentially around the receiving cavity to prevent the sample inside the receiving cavity from flowing out of the opening.

[0042] In other embodiments of this application, the container cap further includes at least one auxiliary splash guard disposed in the puncture channel, the auxiliary splash guard being distributed on at least one side above and below the first puncture member and located above the first opening; the auxiliary splash guard is arranged to extend radially along the puncture channel to block the sample from splashing; and the auxiliary splash guard forms or has a structure that allows the sampling component to pass through.

[0043] In other embodiments of this application, at least one of the auxiliary splash-proof components is a second puncture component. The first puncture component and the second puncture component are spaced apart along the axial direction of the container body. The structure through which the sampling component passes is a closed flexible part or a preset opening. The sampling component can be inserted into the sample in the inner cavity by piercing the flexible part or passing through the opening.

[0044] In other embodiments of this application, the auxiliary splash guard is a plurality of protrusions extending radially from the inner wall of the puncture channel. On a projection plane perpendicular to the axis of the puncture channel, each of the protrusions is distributed in a shape surrounding the axis of the puncture channel, and the area of ​​the puncture channel that the protrusions cover laterally is greater than two-thirds of the lateral area of ​​the puncture channel. The protrusions form passageways between each other for the sampling component to pass through, and the passageways serve as the structure for the sampling component to pass through.

[0045] In other embodiments of this application, each of the protrusions is arranged in a ring shape along the circumference of the inner wall of the puncture channel;

[0046] Alternatively, each of the protrusions may be arranged in a spiral pattern along the inner wall of the puncture channel;

[0047] Alternatively, the protrusions are staggered along the circumferential and axial directions at different positions on the inner wall of the puncture channel.

[0048] In other embodiments of this application, the container cap has an integral cylindrical structure, the puncture channel is located on the cylindrical structure, and the first puncture member is installed on the cylindrical structure.

[0049] In other embodiments of this application, the container cap includes a puncture section, a connecting section, and a flip connector. The connecting section is used to connect to the container body. The puncture section is connected to the connecting section through the flip connector. The puncture section can be flipped relative to the connecting section to close or open the first opening. When the puncture section and the connecting section are docked, the puncture channel is provided through the puncture section and the connecting section.

[0050] In other embodiments of this application, the inner wall of the puncture channel has a second flange extending inwardly along its inner circumference, and the first puncture member is fixedly mounted on the second flange.

[0051] In other embodiments of this application, the first puncture element is configured as a puncture membrane; preferably, the puncture membrane is configured as a rubber membrane, silicone membrane, aluminum membrane, tin membrane or paper membrane; preferably, the thickness of the puncture membrane is 0.1 mm to 2 mm; more preferably, the thickness of the puncture membrane is 0.5 mm to 1 mm.

[0052] To achieve one of the above objectives, some embodiments of this application provide a sample analysis device, including:

[0053] The sample container as described in any of the preceding claims is used to hold a sample;

[0054] The sample introduction mechanism has a suction position for placing a sample container containing a sample;

[0055] A sampling mechanism, comprising a sampling needle, which is used to draw a sample from the corresponding sample container at the sampling position and deliver it to a designated location;

[0056] A testing organization, which is used to test the processed samples;

[0057] And a control unit, which is used to control the sample injection mechanism, the sample suction mechanism and the detection mechanism.

[0058] Additional aspects and advantages of this application will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of this application. Attached Figure Description

[0059] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein:

[0060] Figure 1 This is a cross-sectional view of a sample container in one embodiment of the present invention;

[0061] Figure 2 for Figure 1 A cross-sectional view of the container cap of the sample container;

[0062] Figure 3 This is a cross-sectional view of the container cap according to another embodiment of the present invention;

[0063] Figure 4 This is a cross-sectional view of the sample container in another embodiment of the present invention;

[0064] Figure 5 This is a cross-sectional view of a sample container in one embodiment of the present invention;

[0065] Figure 6 This is a schematic diagram showing the comparison between the lateral area of ​​multiple protrusions serving as auxiliary splash guards and the puncture channel on a projection plane perpendicular to the axis of the puncture channel, according to one embodiment of the present invention.

[0066] Figure 7 This is a schematic diagram showing that, in one embodiment of the present invention, multiple protrusions serving as auxiliary splash guards are arranged in a ring shape at the same axial position on the inner wall of the puncture channel.

[0067] Figure 8This is a schematic diagram of multiple protrusions, which serve as auxiliary splash guards, distributed at different axial and circumferential positions on the inner wall of the puncture channel in one embodiment of the present invention.

[0068] Figure 9 This is a demonstration of liquid and foam splashing in a simulated sample and a real sample under suction and dissipation mixing mode in one embodiment of the present invention;

[0069] Figure 10 In one embodiment of the present invention, when the distance between the puncture area and the first opening along the axial direction of the container body is set to be greater than or equal to 5 mm, or the length of the buffer cavity along the axial direction of the container body is greater than or equal to 5 mm, the liquid and foam splashing situation of the sample container in the conventional suction and discharge mixing mode is shown.

[0070] Figure 11 In one embodiment of the present invention, when the distance between the puncture area and the first opening along the axial direction of the container body is set to be greater than or equal to 5 mm, or the length of the buffer cavity along the axial direction of the container body is greater than or equal to 5 mm, the liquid and foam splashing situation of the sample container in the strong suction and discharge mixing mode is shown.

[0071] Figure 12 In one embodiment of the present invention, when the distance between the puncture area and the first opening along the axial direction of the container body is set to be greater than or equal to 10 mm, or the length of the buffer cavity along the axial direction of the container body is greater than or equal to 10 mm, the liquid and foam splashing situation of the sample container in the strong suction and discharge mixing mode is shown.

[0072] Figure 13 In one embodiment of the present invention, when the distance between the puncture area and the first opening along the axial direction of the container body is set to be greater than or equal to 15 mm, or the length of the buffer cavity along the axial direction of the container body is greater than or equal to 15 mm, the liquid and foam splashing situation of the sample container in the strong suction and discharge mixing mode is shown.

[0073] Figure 14 In one embodiment of the present invention, when the distance between the puncture area and the first opening along the axial direction of the container body is set to be greater than or equal to 20 mm, or the length of the buffer cavity along the axial direction of the container body is greater than or equal to 20 mm, the liquid and foam splashing situation of the sample container in the strong suction and dissipation mixing mode is shown.

[0074] Figure label:

[0075] Sample container 10;

[0076] Container body 100, inner cavity 101, first opening 102;

[0077] Container cap 200, connecting section 210, stepped surface 211, puncture section 220, puncture channel 221, first puncture member 230, puncture area 231, second puncture member 240, flipping connector 250, first flange 260, second flange 270, protrusion 280, buffer cavity 201, receiving cavity 202, second opening 203, passage channel 204. Detailed Implementation

[0078] The embodiments of this application are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this application, and should not be construed as limiting this application.

[0079] In the description of this application, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0080] In the description of this application, "several" means one or more, "multiple" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.

[0081] In the description of this application, unless otherwise expressly defined, terms such as "setup," "installation," and "connection" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this application in conjunction with the specific content of the technical solution.

[0082] In the description of this application, the terms "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0083] In related technologies, some sample containers, especially those used for patient-collected samples such as urine samples, are prone to leakage when the cap is not properly closed due to improper patient operation. This leakage occurs when the device uses conventional mechanical rotation or shaking methods for mixing, affecting the application of these sample containers in automated testing. To address this, some embodiments of this application provide a sample analysis device that controls the insertion of a sampling needle into the corresponding sample container and alternately aspirates and drains the sample to achieve proper mixing. This operation eliminates the need to rotate or shake the sample container, and even if the cap is not properly closed, leakage is less likely, making it suitable for automated testing.

[0084] However, during further research on aspiration and mixing, the applicant of this application discovered that the puncture membrane on the cap of some sample containers (such as urinary catheters) is often positioned relatively close to the opening of the catheter. When some patients add samples to the urinary catheter, they may overfill it, for example, until the liquid level is close to the opening. Furthermore, when the aspiration needle passes through the puncture membrane and mixes the sample by aspiration and mixing, the fluctuation of the liquid level can cause sample to splash out from the punctured area of ​​the puncture membrane, resulting in contamination. Moreover, aspiration and mixing itself increases sample splashing, thus exacerbating the risk of spillage.

[0085] For example, please refer to the inventor's experiments on suction and dissipation mixing. Figure 9 ,in Figure 9 The sample shown on the left is a simulated sample, which uses a mixture of DS, eosin, and surfactant to simulate a urine sample. Figure 9 The right side shows a real urine sample. When this simulated sample and the real sample are applied to aspiration and excretion mixing, as shown... Figure 9 As shown, both produced a splashing phenomenon.

[0086] Specifically, the aspiration and displacement mixing experiment employed both a conventional aspiration and displacement mixing mode and a strong aspiration and displacement mixing mode. In the conventional aspiration and displacement mixing mode, the sampling needle first aspirates a certain amount of sample, and then displaces a certain amount of sample, repeating this operation multiple times to achieve sample mixing within the sample container. For example, in some embodiments, in the conventional aspiration and displacement mixing mode, 650 μL of sample is aspirated first, then 600 μL of sample is displaced, repeated multiple times (e.g., 3 times). In the strong aspiration and displacement mixing mode, the sampling needle first aspirates a certain amount of sample, then displaces a certain amount of sample, and then displaces a certain amount of air bubbles to enhance sample mixing. By repeating this aspiration and displacement operation multiple times, strong mixing of the sample within the sample container is achieved. For example, in some embodiments, 500 μL of sample is aspirated first, then 500 μL of sample is displaced, and then 500 μL of air bubbles is displaced, repeated multiple times (e.g., 3 times). Generally, the conventional aspiration and displacement mixing mode is sufficient for normal samples; only a small number of samples, such as hematuria, significantly turbid, or significantly precipitated samples, may require the strong aspiration and displacement mixing mode. Of course, the choice between the conventional suction and discharge mixing mode and the strong suction and discharge mixing mode can be flexibly made by the operator, and this application does not impose any restrictions. Figure 9 As shown, the bubbling and splashing of the simulated sample are similar to those of the real sample, and it can be used to simulate the real sample.

[0087] To address this issue, some embodiments of this application propose a sample container that can provide a buffer cavity between the puncture component and the tube opening. Even if the liquid level in the tube fluctuates and causes sample splashing, the splashed sample is unlikely to splash out from the punctured part of the puncture component. The following description is in conjunction with the accompanying drawings and specific embodiments.

[0088] Reference Figure 1 , Figure 2 The figures show cross-sectional views of the sample container 10 and the cap in some embodiments of this application. As shown, the sample container 10 includes a container body 100 and a container cap 200. The container body 100 is used to contain the sample to be tested, and the container cap 200 is used to close the container body 100 to prevent the sample from splashing out. It should be noted that the sample container 10 involved in this application can be a urine catheter for containing urine samples, or a corresponding container for containing other samples.

[0089] Reference Figure 1The container body 100 has an inner cavity 101 for storing samples. One end of the inner cavity 101 forms a first opening 102 on the container body 100, through which the sample can enter the inner cavity 101. For example, the main body of the container body 100 forms a circular tube structure, with a gradually tapering conical tube structure at the bottom end, and the first opening 102 forming at the top end of the circular tube structure. In some specific embodiments, the outer peripheral surface of the end of the container body 100 with the first opening 102 is also provided with a connecting structure, such as an external thread, for connecting to the container cap 200.

[0090] Please continue to refer to Figure 1 In some embodiments, the container cap 200 includes a connecting section 210 and a puncture section 220, wherein the container cap 200 is connected to the end of the container body 100 having a first opening 102 via at least a portion of the connecting section 210, for example... Figure 1 As shown, exemplarily, the connecting segment 210 is formed as a sleeve structure adapted to the shape and size of the container body 100, and it is fitted onto the top of the container body 100. In some embodiments, all of the connecting segments 210 are used to connect with the container body 100, in which case the upper end surface of the connecting segment 210 is flush with the upper end surface of the container body 100. In other embodiments, the connecting segment 210 is only partially used to connect with the container body 100, in which case the upper end surface of the connecting segment 210 is higher than the upper end surface of the container body 100.

[0091] The puncture segment 220 is connected to the connecting segment 210, specifically to the end of the connecting segment 210 facing away from the container body 100. In some embodiments, the puncture segment 220 and the connecting segment 210 are integrally formed, for example, by integral injection molding. In other embodiments, the puncture segment 220 and the connecting segment 210 can also be separate structures, which will be described in detail in subsequent embodiments. It should be noted that when the puncture segment 220 and the connecting segment 210 are integrally formed, there can be a clear boundary between them, for example... Figure 1 As shown, a stepped surface is provided between the puncture section 220 and the connecting section 210. The upper end surface of the container body 100 abuts against the stepped surface to limit the container cap 200. In addition, there may be no clear boundary between the puncture section 220 and the connecting section 210. In this case, the upper end surface of the container body 100 can be used as the dividing line to distinguish the puncture section 220 and the connecting section 210.

[0092] The container cap 200 also includes a first puncture member 230 connected to the puncture section 220. The first puncture member 230 is used to cooperate with other structures of the container cap 200 to seal the container body 100, preventing sample spillage in the inner cavity 101. On the other hand, the first puncture member 230 can also be punctured by a sampling component, such as a sampling needle, to form a first puncture hole. The sampling component can extend into the sample in the inner cavity 101 of the container body 100 through the first puncture hole to achieve suction and discharge mixing and sampling of the sample by the puncture component. For example, the first puncture member 230 can be a membrane structure or a flexible plug.

[0093] In this embodiment, when the container cap 200 is connected to the container body 100, the container cap 200 has a buffer cavity 201 formed between the first puncture member 230 and the first opening 102. The buffer cavity 201 is configured to buffer the sample splashed from the first opening 102 to the first puncture member 230 during the suction and mixing process. Specifically, the splashed sample is affected by factors such as gravity, and it will fall after rising to a certain height. Therefore, by setting a buffer cavity 201 with a certain height between the first puncture member 230 and the first opening 102, the splashed sample can be reduced or avoided from splashing out through the punctured part of the first puncture member 230, thereby reducing the risk of contamination. It should be noted that most manufacturers have not yet recognized the splashing problem of such sample containers (especially urinary catheters) that require active operation by patients. This application proposes a simple and reliable solution to this problem, which can improve the splashing problem of such sample containers at low cost.

[0094] Based on the above embodiments, in some embodiments of this application, the aforementioned "buffer cavity 201 is configured to buffer the sample splashed from the first opening 102 to the first puncture member 230 during the suction and discharge mixing process" specifically means that the buffer cavity 201 is configured to prevent part or all of the splashed sample from splashing out of the first puncture hole during the suction and discharge mixing process. That is, in this embodiment, the buffering capacity of the buffer cavity 201 needs to be sufficient to prevent the splashed sample from splashing out of the first puncture hole. Specifically, this includes situations where the splashed sample does not contact the first puncture member 230 and, although it contacts the first puncture member 230, it does not completely pass through the first puncture hole. In some scenarios, the buffer chamber 201 has a strong buffering capacity, which can prevent all the splashed sample from splashing out of the first puncture hole. In other scenarios, the buffer chamber 201 has a weaker buffering capacity, and some samples may be able to pass through the first puncture hole due to factors such as initial velocity and splashing direction. Even so, compared with the solution in related technologies that does not set up a buffer chamber 210, it still solves the problem of sample splashing to a certain extent.

[0095] Based on the above embodiments, in some embodiments of this application, the length of the buffer cavity 201 along the axial direction of the container body 100 is greater than or equal to 5 mm. This height range can accommodate sample splashing caused by suction and discharge mixing in most cases. In some specific embodiments, the length of the buffer cavity 201 along the axial direction of the container body 100 is greater than or equal to 15 mm. Within this height range, sample splashing caused by suction and discharge mixing can be significantly reduced or even eliminated. In some specific embodiments, the length of the buffer cavity 201 along the axial direction of the container body 100 is less than or equal to 20 mm. This satisfies the requirement to prevent sample splashing without excessively increasing the height of the sample container 10, making the sample container 10 of this application suitable for automated analysis equipment. For example, the length of the buffer cavity 201 along the axial direction of the container body 100 is 15 mm, 16 mm, 17 mm, 18 mm, 19 mm, or 20 mm.

[0096] It should be noted that in some embodiments, the axial length of the buffer cavity 201 varies at different positions. In this case, the "length of the buffer cavity 201 along the axial direction of the container body 100" mentioned above refers to the maximum axial length.

[0097] Of course, another sample container is also provided in some other embodiments of this application; please refer to [reference needed]. Figure 5 The sample container 10 also includes a container body 100 and a container cap 200. The container body 100 can adopt, but is not limited to, the structures shown in the above embodiments. Unlike the previous embodiments, in this embodiment, the container cap 200 includes a puncture channel 221, but it does not necessarily have to be divided into a puncture section 220 and a connecting section 210. The puncture channel 221 is a channel for a sampling component (such as a sampling needle) to be inserted into and pass through the container cap 200. The container cap 200 can adopt any feasible structure to form the puncture channel 221, for example, in a container cap 200 using... Figure 5 When the cap structure shown is integrally molded, the puncture channel 221 can be formed by the cap structure itself; when the container cap 200 adopts... Figure 4 When the split structure shown is assembled into a normal use state, it can form a corresponding puncture channel 221.

[0098] In addition, please refer to Figure 5 The container cap 200 also includes a first puncture member 230 that blocks the puncture channel 221. Typically, the first puncture member 230 blocks the puncture channel 221 in a radially extending manner within it. The first puncture member 230 can either completely seal the puncture channel 221 or provide a defined opening. The container cap 200 can be attached to the end of the container body 100 that has the first opening 102, such as... Figure 5As shown, when the container cap 200 covers the container body 100, the puncture channel 221 is sealed and connected to the first opening 102. Here, "sealed and connected" means that one end of the puncture channel 221 and the first opening 102 are sealed and connected to each other and fixedly connected (the fixed connection can be achieved by, but is not limited to, existing fixed structures of the container cap 200 and the container body 100), but it does not mean that the entire area of ​​the puncture channel 221 from top to bottom must be completely connected to the first opening 102.

[0099] Please continue to refer to Figure 5 When the container cap 200 is connected to the end of the container body 100 with the first opening 102, the first puncture member 230 is located above the first opening 102. It should be noted that the up and down directions mentioned in this application are based on the sample container 10 being in a normal usage posture, such as the posture when the sample container 10 is being injected, the posture when the sample container 10 is being aspirated and mixed, or the posture when the sample container 10 is being sampled by a sampling component. The main function of the first puncture member 230 is to seal the inner cavity of the container body 100, preventing easy leakage of the sample from the sample container 10. It also needs to allow a sampling component (such as a sampling needle) to be inserted and pass through the first puncture member 230. Therefore, the first puncture member 230 has a puncture area 231 through which a sampling component can pass, allowing the sampling component to pass through the puncture area 231 and extend into the sample inside the inner cavity for aspiration and mixing. The puncture area 231 mentioned here refers to the portion of the first puncture member 230 that can be penetrated by the sampling component. This penetration can be either a puncture or a non-puncture process; for example, the sampling component can penetrate a pre-set opening in the puncture area 231 in a non-puncture manner. Specifically, the puncture area 231 can adopt a sealing structure in the aforementioned embodiments that can be punctured by a sampling component such as a sampling needle to form a first puncture hole. Alternatively, the puncture area 231 can also have a pre-set through opening, such as a cut through which the sampling component can pass. When the puncture area 231 has a pre-set opening, different configurations can be used depending on the situation. For example, when the sample container 10 has high requirements for sample sealing and preservation, the walls of the pre-set opening can maintain normal sealed contact due to the material's own extensibility or the compression of surrounding components, thus still achieving a certain degree of sealing effect; when the sample container 10 does not have high requirements for sample sealing and preservation, the opening can remain normally open.

[0100] When the sampling component passes through the first puncture member 230 for aspiration and mixing, to prevent sample from leaking out of the first puncture member 230 due to liquid surface fluctuations and the gap between the first puncture member 230 and the sampling component, please refer to... Figure 5In this embodiment, the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is set to a preset size to reduce or eliminate the situation where the sample in the container body 100 splashes into the first puncture area 231, thereby reducing or avoiding the phenomenon of the sample leaking out of the first puncture member 230 from the insertion point of the sampling member and reducing the risk of contamination.

[0101] Of course, the amount of sample splashing during the aspiration and dissipation mixing process is greatly related to the aspiration and dissipation mixing parameters. Stronger dissipation force will naturally produce more sample splashing. In this case, it is necessary to set a larger distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 to reduce or eliminate sample leakage from the first puncture part 230. Therefore, determining the appropriate distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is not an easy task.

[0102] To further explore the relationship between different distances and splash-proof effects, the inventors conducted experimental verification at different distances using both the aforementioned conventional suction and discharge mixing mode and the strong suction and discharge mixing mode. In some embodiments of this application, when the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is set to be greater than or equal to 5 mm, or the length of the buffer cavity 201 along the axial direction of the container body 100 is greater than or equal to 5 mm, see... Figure 10 As shown, within this range, conventional suction and dissipation mixing will not cause sample leakage or will only result in reduced leakage. Therefore, through theoretical calculations and experimental verification, this distance can effectively reduce or eliminate sample splashing into the first puncture area 231 when performing conventional suction and dissipation mixing on most of the samples within the container body 100, thereby reducing or avoiding the phenomenon of sample leakage from the first puncture component 230 when the sampling component is inserted, and reducing the risk of contamination. However, in some special cases where a strong suction and dissipation mixing mode is required, such as... Figure 11 As shown, sample leakage may still exist.

[0103] In other embodiments, when the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is set to be greater than or equal to 10 mm, or the length of the buffer cavity 201 along the axial direction of the container body 100 is greater than or equal to 10 mm, the conventional suction and discharge mixing mode will not cause leakage within this range. However, in the strong suction and discharge mixing mode, such as Figure 12 As shown, this also significantly reduces leakage, preventing operator complaints.

[0104] Furthermore, in some embodiments, when the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is further set to be greater than or equal to 15 mm, or when the length of the buffer cavity 201 along the axial direction of the container body 100 is greater than or equal to 15 mm, the conventional suction and discharge mixing mode will basically not cause leakage within this range. However, in the strong suction and discharge mixing mode, such as... Figure 13 As shown, the leak has been almost completely eliminated, with only a slight leakage remaining.

[0105] Of course, the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100, or the length of the buffer cavity 201 along the axial direction of the container body 100, is not necessarily better the larger it is. An excessively large distance will excessively increase the height of the sample container 10, making the sample container 10 less adaptable to the equipment. Therefore, in some embodiments, the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is further limited to less than or equal to 20 mm, or the length of the buffer cavity 201 along the axial direction of the container body 100 is greater than or equal to 20 mm. This range can almost meet the anti-splash requirements under most suction and discharge mixing operations, and will not cause leakage not only in the conventional suction and discharge mixing mode, but also in the strong suction and discharge mixing mode, such as... Figure 14 As shown, leakage is virtually nonexistent. Furthermore, the overall height of the sample container can be controlled within the desired range, for example, to no more than 119 mm. This height allows the sample container to be adapted to most analytical equipment, thus improving its versatility.

[0106] Although the above embodiments provide specific values ​​such as 5mm, 10mm, 15mm, and 20mm, in practice any value within the range of 5-20mm can be selected, such as 16mm, 17mm, 18mm, 19mm, or 20mm.

[0107] It should be noted that the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 mentioned in the above embodiments refers to the shortest distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100.

[0108] Furthermore, in the existing sample container 10, the assembly between the container cap 200 and the container body 100 is mainly for sealing and fixing, without deliberately controlling the distance between the puncture area 231 and the first opening 102 after assembly. In some embodiments of this application, in order to ensure that the distance between the puncture area 231 and the first opening 102 after the assembly of the container cap 200 and the container body 100 can be accurately formed as defined above, the container cap 200 includes a limiting structure for upper limit of the container body 100. The limiting structure is located below the first puncture member 230, and the distance between the limiting structure and the first puncture member 230 along the axial direction of the container body 100 is configured to ensure that the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is greater than or equal to 5mm. For example, the distance between the limiting structure and the first puncture member 230 along the axial direction of the container body 100 can also be set to be greater than or equal to 5mm. When the container cap 200 and the container body 100 are assembled, it can be ensured that the distance between the puncture area 231 and the first opening 102 meets the expected design.

[0109] Please refer to Figure 5 More specifically, in some embodiments, the limiting structure includes a stepped surface 211. When the container cap 200 covers the container body 100, the stepped surface 211 is located above the upper end face of the first opening 102, and the two abut against each other vertically. The distance between the stepped surface 211 and the first puncture member 230 along the axial direction of the container body 100 is greater than or equal to 5 mm, thus ensuring that the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is greater than or equal to 5 mm.

[0110] Further, please refer to Figure 5 In some embodiments, to achieve docking between the container cap 200 and the container body 100, the container cap 200 includes a docking structure for connecting to the outer side wall of the container body 100. When the container cap 200 covers the container body 100, the docking structure is located below the first puncture member 230, and the distance between the docking structure and the first puncture member 230 along the axial direction of the container body 100 is greater than 5 mm, so as to ensure that the distance between the puncture area 231 and the first opening 102 along the axial direction of the container body 100 is greater than or equal to 5 mm. The docking structure can adopt any feasible fixed connection structure, such as, but not limited to, a threaded structure, a snap-fit ​​structure, an adhesive structure, an elastic fit structure, or a tight fit structure. Specifically, in Figure 5 In the embodiment shown, the docking structure is an internal thread located inside the cap structure, which is screwed and fixed to the external thread on the outer side wall of the container body 100.

[0111] Based on the above embodiments, in some embodiments of this application, the puncture channel 211 further forms a receiving cavity 202. (Refer to...) Figure 1 The first puncture member 230, on the side opposite to the first opening 102, forms a receiving cavity 202 with the puncture section 220. And... Figure 5 In the illustrated embodiment, the puncture channel 221 has a receiving cavity 202 located above the first puncture member 230. This receiving cavity 202 has an opening facing away from the first opening 102 (referred to as the second opening 203 for ease of description). In some specific embodiments, the puncture segment 220 has a puncture channel 221 extending axially along the container body 100. For example, when the puncture segment 220 and the connecting segment 210 are connected as a single structure, the entire container cap 200 has an axially penetrating through-hole. The portion of this through-hole located in the puncture segment 220 is the puncture channel 221, and the portion located in the connecting segment 210 is the connecting channel. The first puncture member 230 is disposed within the puncture channel 221; that is, a certain distance is spaced between the first puncture member 230 and the openings at both ends of the puncture channel 221. Thus, the side of the first puncture member 230 facing away from the first opening 102 (e.g., Figure 1 The upper part of the puncture channel 221 (shown above) forms a receiving cavity 202 with a certain depth. The receiving cavity 202 forms a second opening 203 at the end of the puncture section 220. That is, the receiving cavity 202, the first puncture component and the buffer cavity 201 are arranged sequentially in the direction away from the container body 100 and close to the container body 100. For example, the receiving cavity 202 is located at the upper end of the entire container cap 200.

[0112] These embodiments are provided with a receiving cavity 202. During the extraction process of the sampling component, if any sample liquid adhering to its outer wall drips, it will remain in the receiving cavity 202, preventing it from flowing further to other locations and further reducing contamination. Based on this, in some specific embodiments, even if a small amount of splashed sample passes through the first puncture member 230, it will still remain in the receiving cavity 202 and will not splash out further.

[0113] When the puncture segment 220 also forms a receiving cavity 202, in some embodiments of this application, refer to Figure 2 Along the direction from the receiving cavity 202 to the buffer cavity 201, for example along Figure 2 From top to bottom, the cross-sectional area of ​​the receiving cavity 202 increases, that is, the receiving cavity 202 is formed into a conical cavity structure with a smaller top and a larger bottom. In this way, when the sample container 10 is tilted, the sample (usually only a small amount of sample) in the receiving cavity 202 will still remain in the receiving cavity 202, which can prevent it from flowing out and causing contamination.

[0114] When the puncture segment 220 also forms a receiving cavity 202, in some embodiments of this application, refer to Figure 2The cavity wall of the receiving cavity 202 has at least one first flange 260 extending circumferentially around the cavity 202. Thus, when the sample container 10 is tilted, the sample (typically only a small amount) within the receiving cavity 202 is blocked by the first flange 260, preventing it from flowing out and causing contamination. In some specific embodiments, the cavity wall of the receiving cavity 202 has multiple first flanges 260, thereby further enhancing the ability to block sample liquid.

[0115] It should be noted that the above embodiments can be combined, that is, the cross-sectional area of ​​the receiving cavity 202 increases along the direction from the receiving cavity 202 to the buffer cavity 201, and the cavity wall of the receiving cavity 202 has at least one first flange 260 extending circumferentially along the receiving cavity 202, that is... Figure 2 The proposed solution aims to further prevent sample leakage.

[0116] In other embodiments of the present invention, to improve the splash-proof effect, the container cap 200 further includes at least one auxiliary splash-proof component disposed in the puncture channel 221. This auxiliary splash-proof component is distributed on at least one side above and below the first puncture member 230, and is located above the first opening 102. The auxiliary splash-proof component forms or has a structure that allows the sampling component to pass through, thus not affecting the normal operation of the sampling component. The auxiliary splash-proof component extends radially along the puncture channel 221 to block sample splashing. When the auxiliary splash-proof component is distributed above the first puncture member 230, it can further limit the outward leakage of sample leaking from the first puncture member 230, i.e., forming at least one protective structure above the first puncture member 230; when the auxiliary splash-proof component is distributed below the first puncture member 230, it is used to reduce and prevent the movement of splashed sample towards the location of the first puncture member 230, i.e., forming at least one protective structure below the first puncture member 230. Therefore, the splashed sample needs to pass through at least two splash-proof structures to reduce the splashing of the sample and thus reduce the risk of contamination.

[0117] Specifically, in some embodiments of this application, reference is made to Figure 3 At least one auxiliary splash-proof component is a second puncture component 240, and the first puncture component 230 and the second puncture component 240 are axially spaced apart along the container body 100. In this embodiment, the structure on the second puncture component 240 through which the sampling component passes is a closed flexible part or a pre-set opening, and the sampling component can be inserted into the sample inside the cavity by piercing the flexible part or passing through the opening.

[0118] More specifically, in some embodiments, please refer to Figure 3The second puncture member 240 is connected to the puncture section 220. Similar to the first puncture member 230, the second puncture member 240 can be punctured by the sampling component to form a second puncture hole. The sampling component can extend into the sample inside the inner cavity 101 of the container body 100 through the second puncture hole. It can also be a membrane structure or a flexible plug. In this embodiment, the first puncture member 230 and the second puncture member 240 are spaced apart along the axial direction of the container body 100. In this way, splashed samples need to pass through two layers of puncture members, which can further improve the splash prevention capability.

[0119] Specifically, in some embodiments, the first puncture element 230 is a puncture membrane, while in other embodiments, it is a puncture plug. The puncture membrane and the puncture plug can be distinguished according to the following criteria: the ratio of the thickness to the diameter of the puncture membrane is much smaller than the ratio of the thickness to the diameter of the puncture plug; the puncture membrane is easily deformable, while the puncture plug is not easily deformable; the puncture membrane facilitates puncture of the sampling component, while the puncture plug has relatively better sealing performance. The two can be selected according to actual needs. In some embodiments, the puncture membrane is set as a rubber membrane, silicone membrane, aluminum membrane, tin membrane, or paper membrane. In some embodiments, the thickness of the puncture membrane is 0.1mm to 2mm, which, in the thickness direction, allows the puncture membrane to achieve both sealing and easy puncture. In some specific embodiments, the thickness of the puncture membrane is 0.5mm to 1mm; for example, the thickness of the puncture membrane is 0.5mm, 0.6mm, 0.7mm, 0.8mm, 0.9mm, or 1mm.

[0120] Similarly, in some embodiments, the second puncture element 240 is a puncture membrane, while in other embodiments it is a puncture plug. The meanings of puncture membrane and puncture plug are understood with reference to the foregoing embodiments. In some embodiments, the thickness of the puncture membrane is 0.1 mm to 2 mm, in which direction of thickness, the puncture membrane can achieve both sealing function and easy puncture. In some specific embodiments, the thickness of the puncture membrane is 0.5 mm to 1 mm; for example, the thickness of the puncture membrane is 0.5 mm, 0.6 mm, 0.7 mm, 0.8 mm, 0.9 mm, or 1 mm.

[0121] It should be noted that in some specific embodiments, the second puncture member 240 can both prevent sample splashing and seal the inner cavity 101 of the container body 100. In other specific embodiments, the second puncture member 240 mainly prevents sample splashing, and the sealing function is mainly achieved by the first puncture member 230. Based on this, the first puncture member 230 and the second puncture member 240 can be puncture members of the same material and / or the same structure, or they can be puncture members of different materials and / or different structures. For example, when the first puncture member 230 mainly serves a sealing function and the second puncture member 240 mainly serves a blocking function, the first puncture member 230 can be made of a more elastic material and / or structure, such as a rubber membrane or silicone membrane, so that when the sampling component is removed from the first puncture member 230, the first puncture member 230 can reset to close the puncture opening; correspondingly, the material of the second puncture member 240 is not limited, but its thickness can be set to be thicker to increase the path of the sample through its puncture opening; when the second puncture member 240 serves both a sealing and blocking function, the second puncture member 240 can also be made of a more elastic material and / or structure, in which case the sealing requirements of the first puncture member 230 can be reduced, for example, the elastic reset capability of the first puncture member 230 can be reduced.

[0122] When the container cap 200 also includes a second puncture member 240, in some embodiments of this application, refer to Figure 3 The second puncture member 240 is disposed in the buffer cavity 201. That is, the splashed sample must pass through the second puncture member 240 before it can reach the first puncture member 230. Due to the blocking effect of the second puncture member 240, very few samples can pass through the second puncture member 240. At this time, even if the sample passes through the second puncture member 240, its speed has been greatly reduced, so it is difficult for it to rise further and contact the first puncture member 230. Therefore, this embodiment can further reduce the splashing of samples. For example, the second puncture member 240 is disposed approximately in the middle of the buffer cavity 201. That is, there is a certain distance between the second puncture member 240 and the first puncture member 230. On the one hand, the buffering function of the buffer cavity 201 below the second puncture member 240 can be used to reduce the amount of liquid reaching the second puncture member 240 and reduce the speed of the sample reaching the second puncture member 240. On the other hand, even after the sample passes through the second puncture member 240, the buffering function of the buffer cavity 201 above the second puncture member 240 can still reduce the amount of liquid reaching the first puncture member 230 and reduce the speed of the sample reaching the first puncture member 230.

[0123] When the container cap 200 also includes a second puncture member 240, in some embodiments of this application, the side of the first puncture member 230 opposite to the first opening 102 forms a receiving cavity 202 with the puncture section 220. In some specific embodiments, refer to... Figure 2 , Figure 3 The puncture section 220 has a puncture channel 221 extending axially along the container body 100. A first puncture member 230 is disposed within the puncture channel 221. A portion of the puncture channel 221 on the side of the first puncture member 230 opposite to the first opening 102 forms a receiving cavity 202, and a second opening 203 is formed at the end of the puncture section 220. The location and function of the receiving cavity 202 in this embodiment can be understood with reference to the aforementioned embodiment, that is, it can be used to accommodate samples separated from the self-sampling component. In this embodiment, the second puncture member 240 is disposed within the receiving cavity 202. That is, the splashed sample needs to pass through the first puncture member 230 before reaching the second puncture member 240. Due to the blocking effect of the first puncture member 230, very little sample can pass through the first puncture member 230. At this time, even if the sample passes through the first puncture member 230, its speed has been greatly reduced, making it difficult to rise further and contact the second puncture member 240. Therefore, this embodiment can further reduce sample splashing.

[0124] Based on the above embodiments, in some specific embodiments, even if a small amount of splashed sample passes through the first puncture hole of the first puncture member 230 and / or further passes through the second puncture hole of the second puncture member 240, it will still remain in the receiving cavity 202 and will not splash out further.

[0125] In other embodiments, the second puncture member 240, together with the first puncture member 230 and the puncture segment 220, forms a receiving cavity. In some specific embodiments, refer to... Figure 2 , Figure 3 The puncture section 220 has a puncture channel 221 extending axially along the container body 100. A first puncture member 230 is disposed within the puncture channel 221. A portion of the puncture channel 221 on the side of the first puncture member 230 opposite to the first opening 102 forms a receiving cavity 202. The receiving cavity 202 forms a second opening 203 at the end of the puncture section 220. A second puncture member 240 covers the second opening 203. In this embodiment, the second puncture member 240 is disposed at the second opening 203 of the receiving cavity 202. That is, the splashed sample needs to pass through the first puncture member 230 before reaching the second puncture member 240. Due to the blocking effect of the first puncture member 230, very little sample can pass through the first puncture member 230. At this point, even if the sample passes through the first puncture member 230, its speed has been greatly reduced, making it difficult for it to rise further and contact the second puncture member 240. Therefore, this embodiment can further reduce sample splashing.

[0126] Based on the above embodiments, in some specific embodiments, even if a small amount of splashed sample passes through the first puncture hole of the first puncture member 230, it will still remain in the receiving cavity 202 and will not splash out further.

[0127] In addition to the second puncture element 240 described above, in other embodiments of this application, such as Figure 6-8 As shown, the auxiliary splash guard can also be a plurality of protrusions 280 extending radially from the inner wall of the self-piercing channel 221. These protrusions 280 block upward splashing samples within the piercing channel 221, thereby reducing sample leakage from the container cap 200 to a certain extent. The protrusions 280 form passageways 204 between each other, which can serve as a structure for the sampling component to pass through.

[0128] Please refer to Figure 6 In some embodiments, to better block upward-splashing samples, the protrusions 280 are distributed around the axis of the puncture channel 221 on the projection plane perpendicular to the axis of the puncture channel 221. The area of ​​the protrusions 280 that laterally covers the puncture channel 221 is greater than two-thirds of the lateral area of ​​the puncture channel 221, thereby expanding the coverage area of ​​the auxiliary splash guard while ensuring that the sampling component can pass through normally. Preferably, the area of ​​the protrusions 280 that laterally covers the puncture channel 221 is greater than three-quarters, or even more than four-fifths, etc.

[0129] These protrusions 280 can be distributed in various ways on the inner wall of the puncture channel 221, as long as they collectively shield the upward-splashing sample. For example, in some embodiments, please refer to... Figure 7 Each protrusion 280 is arranged in a ring around the inner wall of the puncture channel 221; please refer to Figure 8 In some embodiments, the protrusions 280 are staggered along the circumferential and axial directions at different positions on the inner wall of the puncture channel 221; in other embodiments, the protrusions 280 may also be arranged in a spiral along the inner wall of the puncture channel 221.

[0130] Of course, the above are just some specific examples of auxiliary splash guards. In other embodiments, the auxiliary splash guard may also adopt other structures, which are too numerous to list here.

[0131] Furthermore, based on the above embodiments, in some embodiments of this application, reference is made to... Figure 1 , Figure 2 and Figure 5The puncture segment 220 and the connecting segment 210 are configured as an integral cylindrical structure, exemplarily formed by injection molding. Based on this, the container cap 200 is threadedly connected to the end of the container body 100 with the first opening 102 via at least a portion of the connecting segment 210. This allows medical personnel to smoothly rotate and open the container cap 200 without excessive movement that could cause sample spillage. For example, the inner wall of the connecting segment 210 has internal threads, and the circumferential surface of the end of the container body 100 has external threads. The connecting segment 210 is fitted onto the end of the container body 100 and is threadedly connected via the external and internal threads. In other embodiments, the container cap 200 is snapped onto one end of the container body 100 having a first opening 102 by at least a portion of the connecting segment 210. For example, the inner wall of the connecting segment 210 and the peripheral surface of the end of the container body 100 both have snap-fit ​​structures such as snap-fit ​​flanges. By applying a force to the container cap 200 toward or away from the container body 100, the snap-fit ​​structures can be snapped together or separated.

[0132] In other embodiments of this application, reference is made to Figure 4 The puncture segment 220 and the connecting segment 210 are configured as separate cylindrical structures. The container cap 200 also includes a flip connector 250. The puncture segment 220 is connected to the connecting segment 210 via the flip connector 250, and the puncture segment 220 can be flipped relative to the connecting segment 210 to close or open the first opening 102. For example, the flip connector 250 is configured as a connecting strip capable of elastic deformation, with its two ends connected to the puncture segment 220 and the connecting segment 210, respectively. It should be noted that closing or opening the first opening 102 specifically refers to the first opening 102 being in a closed state or in a state that allows the sample to enter, and does not mean that the puncture segment 220 must be in contact with the container body 100.

[0133] When the puncture segment 220 and the connecting segment 210 are configured as separate cylindrical structures, the container cap 200 is threadedly connected to the end of the container body 100 with the first opening 102 via at least a portion of the connecting segment 210. This allows medical personnel to smoothly rotate and open the container cap 200 without excessive force that could cause sample spillage. For example, the inner wall of the connecting segment 210 has internal threads, and the circumferential surface of the end of the container body 100 has external threads. The connecting segment 210 is fitted onto the end of the container body 100 and threadedly connected via the external and internal threads. In other embodiments, the container cap 200 is snapped onto the end of the container body 100 with the first opening 102 via at least a portion of the connecting segment 210. For example, both the inner wall of the connecting segment 210 and the circumferential surface of the end of the container body 100 have snap-fit ​​structures such as snap-fit ​​flanges. By applying a force to the container cap 200 toward or away from the container body 100, the snap-fit ​​structures can be engaged or disengaged.

[0134] When the puncture segment 220 and the connecting segment 210 are configured as separate cylindrical structures, and when the puncture segment 220 closes the first opening 102, refer to Figure 3 A portion of the buffer cavity 201 is formed within the puncture section 220, and another portion is formed within the connecting section 210. Exemplarily, the lower end of the connecting section 210 is fitted onto the outside of the container body 100, and the upper end extends beyond the upper surface of the container body 100. In this embodiment, the other portion of the buffer cavity 201 is formed within the portion of the connecting section 210 that extends beyond the container body 100. In other embodiments, when the puncture section 220 closes the first opening 102, the buffer cavity 201 is formed within the puncture section 220. Exemplarily, the upper surface of the connecting section 210 is flush with the upper surface of the container body 100. In other embodiments, the buffer cavity 201 is formed within the connecting section 210. Exemplarily, the lower end of the connecting section 210 is fitted onto the outside of the container body 100, and the upper end extends beyond the upper surface of the container body 100. In this embodiment, the first puncture member is disposed on the lower surface of the puncture section 220.

[0135] In some specific embodiments, a snap-fit ​​structure for mutual fixation is also provided between the puncture segment 220 and the connecting segment 210. For example, the inner diameter of the puncture segment 220 is equal to or slightly larger than the outer diameter of the connecting segment 210, and the inner wall surface of the puncture segment 220 and the outer wall surface of the connecting segment 210 are provided with a snap-fit ​​structure, such as a snap-fit ​​flange. When it is necessary to close the first opening 102, the lower end of the puncture segment 220 is sleeved on the outer side of the upper end of the connecting segment 210, and the two are snap-fitted and fixed by the snap-fit ​​flange of the two.

[0136] Based on the above embodiments, the inner wall of the puncture section 220 or puncture channel has a second flange 270 extending circumferentially and protruding inward, and the first puncture member is fixedly mounted on the second flange. In some specific embodiments, refer to... Figure 1 , Figure 2 The puncture section 220 has a puncture channel 221 extending axially along the container body 100. The puncture channel 221 can be understood with reference to the aforementioned embodiments. The channel wall of the puncture channel 221 is provided with a second flange 270 extending circumferentially along the puncture channel 221. The edge of the first puncture member 230 is connected to the second flange 270. By setting the second flange 270 as the mounting base for the first puncture member 230, a stable connection of the first puncture member 230 can be achieved, ensuring a sealing effect. For example, the edge of the first puncture member 230 is fixed to the second flange 270 by ultrasonic welding or bonding. In some specific embodiments, the upper end face of the second flange 270 forms a mounting plane, and the first puncture member 230 is connected to the upper mounting plane. In other specific embodiments, the lower end face of the second flange 270 forms a mounting plane, and the first puncture member 230 is connected to the lower mounting plane.

[0137] It should be noted that the installation method of the first puncture member 230 is not limited to this. For example, a first groove extending circumferentially along the puncture channel 221 can be provided on the channel wall of the puncture channel 221, and the edge of the first puncture member 230 can be connected to the first groove by welding or bonding.

[0138] Based on the above embodiments, a puncture channel 221 is provided in the puncture section 220, and the puncture channel 221 can be understood with reference to the foregoing embodiments. The channel wall of the puncture channel 221 is provided with a third flange extending circumferentially along the puncture channel 221. The edge of the second puncture member 240 is connected to the third flange. By setting the third flange as the mounting base of the second puncture member 240, a stable connection of the second puncture member 240 can be achieved, ensuring a sealing effect. For example, the edge of the second puncture member 240 is fixed to the third flange by ultrasonic welding or bonding. In some specific embodiments, the upper end face of the third flange forms a mounting plane, and the second puncture member 240 is connected to the upper mounting plane. In other specific embodiments, the lower end face of the third flange forms a mounting plane, and the second puncture member 240 is connected to the lower mounting plane.

[0139] It should be noted that the installation method of the second puncture member 240 is not limited to this. For example, a second groove extending circumferentially along the puncture channel 221 can be provided on the channel wall of the puncture channel 221, and the edge of the second puncture member 240 can be connected to the second groove by welding or bonding.

[0140] On the other hand, some embodiments of this application propose a sample container 10, which includes a container body 100 and a container cap 200. The container body 100 has an inner cavity 101 for storing a sample, and one end of the inner cavity 101 forms a first opening 102 on the container body 100. The container cap 200 is connected to the end of the container body 100 with the first opening 102, and it can seal the first opening 102. The container cap 200 has a puncture member, which can be punctured by a sampling member to allow the sampling member to extend into the sample in the inner cavity 101 of the container body 100, so as to realize the suction and expulsion mixing and sampling of the sample by the puncture member.

[0141] In this embodiment, the container cap 200 also has a splash-proof portion between the puncture member and the first opening 102. The splash-proof portion is located in the puncture path of the sampling member and above the first opening 102. The splash-proof portion is configured to restrict the sample splashed from the first opening 102 from completely passing through the puncture member, thereby avoiding contamination caused by sample overflow. It should be noted that "completely passing through" here should be understood as the sample not being able to completely pass through the puncture hole formed by the sampling member on the puncture member. Specifically, this includes situations where the splashed sample does not contact the first puncture member 230 and situations where, although it contacts the first puncture member 230, it does not completely pass through the first puncture hole.

[0142] It should be noted that when multiple puncture devices are provided, in some specific embodiments, the puncture device and the first opening 102 are further provided with an anti-splash portion. Specifically, the puncture device closest to the first opening 102 and the first opening 102 are provided with an anti-splash portion. In other specific embodiments, the puncture device and the first opening 102 are further provided with an anti-splash portion. Specifically, the puncture device furthest from the first opening 102 and the first opening 102 are provided with an anti-splash portion.

[0143] Furthermore, in some embodiments of this application, the aforementioned "splash-proof portion is configured to limit the sample splashed from the first opening 102 from completely passing through the puncture member" specifically means that the splash-proof portion is configured to prevent some or all of the splashed sample from splashing out of the puncture member. In some scenarios, the splash-proof portion can prevent all the splashed sample from splashing out of the first puncture hole. In other scenarios, some samples may be able to pass through the splash-proof portion due to factors such as initial velocity and splash direction. Even so, compared to the related art's solution without a splash-proof portion, it still solves the problem of sample splashing to a certain extent.

[0144] Based on the second embodiment, in some embodiments of this application, the length of the anti-splash portion along the axial direction of the container body 100 is greater than or equal to 5 mm. This height range can accommodate sample splashing scenarios caused by suction and discharge mixing in most cases. In some specific embodiments, the length of the anti-splash portion along the axial direction of the container body 100 is greater than or equal to 15 mm. Within this height range, sample splashing problems caused by suction and discharge mixing can be significantly reduced or even eliminated. In some specific embodiments, the length of the anti-splash portion along the axial direction of the container body 100 is less than or equal to 20 mm. In this way, the requirement to prevent sample splashing can be met without excessively increasing the height of the sample container 10, making the sample container 10 of this application suitable for automated analysis equipment. For example, the length of the anti-splash portion along the axial direction of the container body 100 is 15 mm, 16 mm, 17 mm, 18 mm, 19 mm, or 20 mm.

[0145] Furthermore, some embodiments of this application also provide a sample analysis device that can achieve both suction and dissipation mixing and can cooperate with the sample containers shown in the above embodiments to complete automated mixing of samples, while reducing or avoiding leakage of samples due to over-flushing during suction and dissipation mixing.

[0146] The sample analysis device includes a sample container 10, a sample introduction mechanism, a sample aspiration mechanism, a detection mechanism, and a control unit, as described above. The sample container 10 is used to hold samples, such as urine or other samples. The sample introduction mechanism, sample aspiration mechanism, detection mechanism, and control unit can all be implemented using similar functional modules found in existing sample analysis devices, but are not limited to. The sample introduction mechanism has a sample aspiration position for placing the sample container 10 containing the sample. The sample introduction mechanism can automatically deliver the sample container 10 to the sample aspiration position, and / or the operator can manually place the sample at the sample aspiration position. The sample aspiration mechanism includes a sampling needle used to draw the sample from the corresponding sample container 10 from the sample aspiration position and deliver it to a subsequently set location, such as a corresponding reaction cell or test strip. The detection mechanism is used to detect the processed sample, for example, using, but not limited to, a colorimetric detection mechanism or other detection mechanisms. The control unit is signal-connected to the sample aspiration mechanism and controls the sampling needle to insert into the corresponding sample container 10 and alternately aspirate and drain the sample within the sample container 10 to achieve sample mixing. The control unit can control the above components, and the specific control method can refer to the existing technology.

[0147] In addition, in some embodiments, the sample analysis device may also include a reaction mechanism and a reagent supply mechanism, if necessary. The reaction mechanism includes at least one reaction chamber for mixing and reacting samples and reagents. The reagent supply mechanism is used to deliver reagents to the corresponding reaction chamber, wherein the reagent supply mechanism itself may have a reagent storage module or may be connected to an external reagent storage module to supply reagents.

[0148] Furthermore, in other embodiments of this application, the outer wall of the sampling needle has a venting groove arranged along its axial direction, so that when the sampling needle is inserted into the sample container 10 for suction and discharge mixing, gas can enter and exit the sample container 10 along the venting groove to regulate the internal and external pressure. However, it is precisely because of the setting of this venting groove that the sample in the sample container 10 is more likely to leak outward along the venting groove due to capillary action. Therefore, in this case, it is even more necessary to use the aforementioned sample container 10 to reduce sample leakage.

[0149] The embodiments of this application have been described in detail above with reference to the accompanying drawings. However, this application is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of this application. Furthermore, unless otherwise specified, the embodiments and features described in the embodiments of this application can be combined with each other.

Claims

1. A sample container, characterized in that, include: A container body having an inner cavity for storing samples, one end of which forms a first opening on the container body; A container cap includes a connecting section and a puncture section connected to the connecting section. The container cap is connected to the end of the container body having the first opening via at least a portion of the connecting section. The container cap also includes a first puncture member connected to the puncture section. The first puncture member can be punctured to form a first puncture hole. A sampling component can be inserted into the sample in the inner cavity of the container body through the first puncture hole and can repeatedly perform the liquid aspiration operation of drawing the sample and the liquid discharge operation of discharging the sample to mix the sample in the inner cavity. When the container cap is connected to the container body, the container cap has a buffer cavity formed between the first puncture member and the first opening. The buffer cavity is configured to buffer the sample splashed from the first opening to the first puncture member during the suction and discharge mixing process.

2. The sample container according to claim 1, characterized in that, The buffer chamber is configured to buffer the sample splashed from the first opening to the first puncture member during the suction and discharge mixing process, including: the buffer chamber is configured to prevent part or all of the splashed sample from splashing out of the first puncture hole during the suction and discharge mixing process.

3. The sample container according to claim 1, characterized in that, The length of the buffer cavity along the axial direction of the container body is greater than or equal to 5 mm.

4. The sample container according to claim 1, characterized in that, The length of the buffer cavity along the axial direction of the container body is greater than or equal to 15 mm.

5. The sample container according to claim 1, characterized in that, The length of the buffer cavity along the axial direction of the container body is less than or equal to 20 mm.

6. The sample container according to claim 1, characterized in that, The first puncture member has a receiving cavity formed with the puncture section on the side opposite to the first opening. The receiving cavity has an opening opposite to the first opening and is used to receive a sample separated from the sampling member.

7. The sample container according to claim 6, characterized in that, The receiving cavity is also used to receive samples that may splash out of the first puncture hole.

8. The sample container according to claim 6, characterized in that, Along the direction from the receiving cavity to the buffer cavity, the cross-sectional area of ​​the receiving cavity increases, and / or, the cavity wall of the receiving cavity has at least one first flange extending circumferentially along the receiving cavity.

9. The sample container according to claim 1, characterized in that, The container cap further includes a second puncture member connected to the puncture section. The first puncture member and the second puncture member are spaced apart along the axial direction of the container body. The second puncture member can be punctured to form a second puncture hole. The sampling component can be inserted into the sample in the inner cavity of the container body through the second puncture hole.

10. The sample container according to claim 9, characterized in that, The second puncture element is disposed within the buffer cavity; Alternatively, the first puncture member on the side opposite to the first opening forms a receiving cavity with the puncture section, and the second puncture member is disposed in the receiving cavity; or, the second puncture member, the first puncture member, and the puncture section together enclose the receiving cavity, and the receiving cavity is used to receive the sample separated from the sampling component.

11. The sample container according to claim 10, characterized in that, The receiving cavity is also used to receive samples that may splash out of the first puncture hole and / or samples that may splash out of the second puncture hole.

12. The sample container according to claim 1, characterized in that, The puncture section and the connecting section are configured as a single cylindrical structure.

13. The sample container according to claim 12, characterized in that, The container cap is threaded to the end of the container body having the first opening via at least a portion of the connecting section, or the container cap is snapped onto the end of the container body having the first opening via at least a portion of the connecting section.

14. The sample container according to claim 1, characterized in that, The container cap also includes a flip connector. The puncture section and the connecting section are configured as separate cylindrical structures. The puncture section is connected to the connecting section through the flip connector, and the puncture section can be flipped relative to the connecting section to close or open the first opening.

15. The sample container according to claim 1, characterized in that, The container cap is threaded to the end of the container body having the first opening via at least a portion of the connecting section, or the container cap is snapped onto the end of the container body having the first opening via at least a portion of the connecting section.

16. The sample container according to claim 15, characterized in that, When the puncture segment closes the first opening, a portion of the buffer cavity is formed within the puncture segment and another portion is formed within the connecting segment; or, the buffer cavity is formed within the puncture segment; or, the buffer cavity is formed within the connecting segment.

17. The sample container according to claim 1, characterized in that, The puncture segment has a second flange that extends circumferentially and protrudes inwardly, and the first puncture member is connected to the second flange.

18. The sample container according to claim 17, characterized in that, The first puncture member is bonded to the second flange, or the first puncture member is welded to the second flange.

19. The sample container according to claim 1, characterized in that, The first puncture element is configured as a puncture membrane.

20. The sample container according to claim 19, characterized in that, The puncture membrane is made of rubber, silicone, aluminum, tin, or paper.

21. The sample container according to claim 19, characterized in that, The thickness of the puncture membrane is 0.1 mm to 2 mm.

22. The sample container according to claim 19, characterized in that, The thickness of the puncture membrane is 0.5 mm to 1 mm.

23. A sample container, characterized in that, include: A container body having an inner cavity for storing samples, one end of which forms a first opening on the container body; A container cap is attached to one end of the container body having the first opening. The container cap also includes a puncture member that can be punctured to allow a sampling component to extend into the sample within the inner cavity of the container body. The puncture member and the first opening have a splash-proof portion configured to prevent the sample splashed from the first opening from completely passing through the puncture member.

24. The sample container according to claim 23, characterized in that, The splash-proof portion is configured to limit the sample splashed from the first opening from completely passing through the puncture member, including: the splash-proof portion is configured to prevent some or all of the splashed sample from splashing out of the puncture member.

25. The sample container according to claim 23, characterized in that, The length of the splash-proof part along the axial direction of the container body is greater than or equal to 5mm.

26. The sample container according to claim 23, characterized in that, The length of the splash-proof part along the axial direction of the container body is greater than or equal to 15mm.

27. The sample container according to claim 23, characterized in that, The length of the splash-proof part along the axial direction of the container body is less than or equal to 20 mm.

28. A sample container, characterized in that, include: A container body having an inner cavity for storing samples, one end of which forms a first opening on the container body; A container cap includes a puncture channel and a first puncture member that forms a barrier to the puncture channel. The container cap can be connected to one end of the container body having the first opening. The first puncture member has a puncture area through which a sampling component can pass, so that the sampling component passes through the puncture area and extends into the sample in the inner cavity for suction, discharge, and mixing. When the container cap covers the container body, the puncture channel is sealed and connected to the first opening, the first puncture member is located above the first opening, and the distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 5 mm.

29. The sample container according to claim 28, characterized in that, The distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 10 mm.

30. The sample container according to claim 28, characterized in that, The distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 15 mm.

31. The sample container according to claim 28, characterized in that, The distance between the puncture area and the first opening along the axial direction of the container body is less than or equal to 20 mm.

32. The sample container according to claim 28, characterized in that, The container cap includes a limiting structure for upper limit of the container body, the limiting structure being located below the first puncture member, and the distance between the limiting structure and the first puncture member along the axial direction of the container body is configured to ensure that the distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 5 mm.

33. The sample container according to claim 32, characterized in that, The limiting structure includes a stepped surface. When the container cap covers the container body, the distance between the stepped surface and the first puncture member along the axial direction of the container body is greater than or equal to 5 mm. The stepped surface is located above the upper end face of the first opening, and the two abut against each other vertically.

34. The sample container according to claim 32, characterized in that, The container cap includes a docking structure for connecting to the outer side wall of the container body. When the container cap covers the container body, the docking structure is located below the first puncture member. The distance between the docking structure and the first puncture member along the axial direction of the container body is greater than 5 mm, so as to ensure that the distance between the puncture area and the first opening along the axial direction of the container body is greater than or equal to 5 mm.

35. The sample container according to claim 28, characterized in that, The puncture channel has a receiving cavity located on the upper side of the first puncture member, the receiving cavity having an opening facing away from the first opening, the receiving cavity being used to receive samples separated from the sampling member, and / or to receive samples splashed from the puncture area.

36. The sample container according to claim 35, characterized in that, Along the direction from the opening to the first opening, the cross-sectional area of ​​the receiving cavity increases to prevent the sample inside the receiving cavity from flowing out of the opening; And / or, the cavity wall of the receiving cavity has at least one first flange extending circumferentially around the receiving cavity to prevent the sample inside the receiving cavity from flowing out of the opening.

37. The sample container according to claim 28, characterized in that, The container cap further includes at least one auxiliary splash guard disposed in the puncture channel, the auxiliary splash guard being distributed on at least one side above and below the first puncture member and located above the first opening; the auxiliary splash guard is arranged to extend radially along the puncture channel to block the sample from splashing; and the auxiliary splash guard forms or has a structure that allows the sampling component to pass through.

38. The sample container according to claim 37, characterized in that, At least one of the auxiliary splash-proof components is a second puncture component. The first puncture component and the second puncture component are spaced apart along the axial direction of the container body. The structure through which the sampling component passes is a closed flexible part or a preset opening. The sampling component can be inserted into the sample in the inner cavity by piercing the flexible part or passing through the opening.

39. The sample container according to claim 37, characterized in that, The auxiliary splash guard consists of multiple protrusions extending radially from the inner wall of the puncture channel. On a projection plane perpendicular to the axis of the puncture channel, each protrusion is distributed in a shape surrounding the axis of the puncture channel, and the area of ​​the protrusions covering the puncture channel laterally is greater than two-thirds of the lateral area of ​​the puncture channel. The protrusions form passageways between each other for the sampling component to pass through, and the passageways serve as the structure for the sampling component to pass through.

40. The sample container according to claim 39, characterized in that, The protrusions are arranged in a ring around the inner wall of the puncture channel. Alternatively, each of the protrusions may be arranged in a spiral pattern along the inner wall of the puncture channel; Alternatively, the protrusions are staggered along the circumferential and axial directions at different positions on the inner wall of the puncture channel.

41. The sample container according to claim 28, characterized in that, The container cap has an integral cylindrical structure, the puncture channel is located on the cylindrical structure, and the first puncture member is installed on the cylindrical structure; Alternatively, the container cap may include a puncture section, a connecting section, and a flip-over connector. The connecting section is used to connect to the container body. The puncture section is connected to the connecting section through the flip-over connector. The puncture section can be flipped relative to the connecting section to close or open the first opening. When the puncture section and the connecting section are aligned, the puncture channel extends through the puncture section and the connecting section.

42. The sample container according to any one of claims 28-41, characterized in that, The inner wall of the puncture channel has a second flange that extends inwardly along its inner circumference, and the first puncture member is fixedly installed on the second flange.

43. A sample analysis device, characterized in that, include: The sample container as described in any one of claims 1-42, wherein the sample container is used to hold a sample; The sample introduction mechanism has a suction position for placing a sample container containing a sample; A sampling mechanism, comprising a sampling needle, which is used to draw a sample from the corresponding sample container at the sampling position and deliver it to a designated location; A testing organization, which is used to test the processed samples; And a control unit, which is used to control the sample injection mechanism, the sample suction mechanism and the detection mechanism.