A separation mechanism for cell culture fluid

Abstract

The utility model relates to cell culture solution separation technical field, and disclose a kind of separation mechanism of cell culture solution, including support chassis, support chassis upper portion is equipped with lower rotary disc, and rotating motor for driving lower rotary disc rotation is fixedly installed in support chassis, support chassis side is fixedly installed with the bearing frame of inverted U shape, bearing frame is equipped with the movable plate that can move up and down, movable plate lower portion is rotatably connected with the upper rotary disc that is adapted with lower rotary disc, and the opposite side of lower rotary disc and upper rotary disc is equipped with several abutment seats, one end is open, and several abutment grooves are equipped in abutment seat, and the size of the inner diameter of several abutment grooves is not identical and is stepped shape. In the utility model, two abutment seats are connected to cell culture bottle, and cell culture bottle is easily taken and placed, and the clamping stability of cell culture bottle is improved.

Description

Technical Field

[0001] This utility model relates to the field of cell culture medium separation technology, specifically a cell culture medium separation mechanism. Background Technology

[0002] In cell culture technology, the separation of cell culture medium is a key operation. Cell culture medium contains a variety of components such as cells, nutrients, and metabolites. In order to obtain pure cells or specific cell metabolites, it is necessary to effectively separate the culture medium, such as by centrifugation.

[0003] A search revealed a patent, CN222024383U, which discloses a cell culture medium separation mechanism. This mechanism includes an operating table, a transmission mechanism, a fixing mechanism, and a convenient mechanism. A control switch is fixedly connected to the upper surface of the operating table. During use, the cell culture medium separation mechanism involves placing the culture flask into a placement sleeve. A motor drives a connecting shaft to rotate, causing the placement sleeve to rotate around the center of the connecting shaft. The placement sleeve is tilted, thus separating the culture medium in the cell culture flask. Next, when the cell culture flask is placed into the placement sleeve, a clamping plate is pushed by a spring to compress it. The spring's rebound force then clamps the cell culture flask. A rubber strip provides anti-slip properties, and an arc groove facilitates fixing the cell culture flask. After separation, a push rod is pushed, moving an arc-shaped base to slowly push the cell culture flask out for easy removal.

[0004] The aforementioned patents have significant beneficial effects, but in practical application, they still have the following shortcomings: The aforementioned comparative documents describe inserting cell culture flasks into a placement sleeve containing several springs. These springs compress clamping plates to hold and fix the cell culture flasks. However, in reality, centrifugation of cell culture media involves high rotation speeds, requiring stable fixation of the flasks. This necessitates the springs applying significant force to the flasks. If the spring's rebound force is too large, the flasks may be difficult to insert or remove from the placement sleeve. Conversely, if the spring's force is too small, the stability of the fixation will be poor, reducing the overall applicability of the cell culture separation device. Therefore, there is an urgent need in the art to improve the cell culture separation mechanism to overcome the shortcomings of the prior art. Utility Model Content

[0005] To address the shortcomings of existing technologies, this invention provides a cell culture medium separation mechanism that facilitates the handling of cell culture flasks and improves the stability of holding the cell culture flasks.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a cell culture medium separation mechanism, comprising a support base, a lower rotating disk on the upper part of the support base, a rotary motor for driving the lower rotating disk to rotate fixedly installed inside the support base, an inverted U-shaped support frame fixedly installed on the side of the support base, a movable plate that can move up and down inside the support frame, an upper rotating disk adapted to the lower rotating disk rotatably connected to the lower part of the movable plate, and several abutment seats with one open end provided on the opposite sides of the lower rotating disk and the upper rotating disk, with several abutment grooves inside the abutment seats, the inner diameter of the several abutment grooves being different and stepped.

[0007] Preferably, two symmetrical and synchronous drive motors are fixedly installed on the upper part of the support frame, and sliding blocks are fixedly installed at both ends of the moving plate. Sliding grooves adapted to the sliding blocks are opened on the opposite side walls inside the support frame. A drive screw with one end fixedly installed to the output end of the drive motor is rotatably connected in the sliding groove. The drive screw passes through the sliding block and is threadedly connected to it.

[0008] Preferably, a positioning seat is fixedly installed on the side of the abutment seat away from the opening end, and positioning grooves adapted to the positioning seat are provided on the sides of both the lower rotating disk and the upper rotating disk.

[0009] Preferably, a number of limiting rods adapted to the positions of the positioning grooves are inserted into the sides of both the lower and upper rotating disks. A limiting groove adapted to the end of the limiting rod is opened on one side of the positioning seat. A pulling plate is fixedly installed on the outer end of the limiting rod. An elastic element sleeved on the side of the limiting rod is fixedly installed between the pulling plate and the side of the lower or upper rotating disk.

[0010] Preferably, a number of ball bearings are provided between the support base and the lower rotating disk.

[0011] Preferably, the upper part of the support base is provided with several embedding slots, and the ball bearings are embedded in the embedding slots and can rotate.

[0012] Preferably, the lower rotating disk has a circular arc-shaped groove at its lower part, which is adapted to the ball bearing.

[0013] To address the shortcomings of existing technologies, this invention provides a cell culture medium separation mechanism, overcoming the deficiencies of the prior art. The beneficial effects of this invention are as follows: In this invention, two abutment seats and abutment grooves are provided inside the abutment seats, and the upper rotating disk can move up and down. The two abutment seats clamp the cell culture flasks, and the abutment seats are provided with several abutment grooves. The inner diameter of each abutment groove is adapted to the outer diameter of commonly used cell culture flasks, which can limit and fix cell culture flasks of different sizes. The two abutment seats clamp and limit the cell culture flasks, which facilitates the picking and putting of cell culture flasks and improves the clamping stability of cell culture flasks.

[0014] In this invention, the positioning seat, positioning groove, limiting rod, and elastic element work together to facilitate the installation of the abutment seat. At the same time, it is easy to replace the abutment seat of different sizes according to the size of the cell culture flask, thereby improving the applicability of the cell culture medium separation equipment.

[0015] Other features and advantages of this invention will be set forth in the description which follows, and will be apparent in part from the description, or may be learned by practicing the invention. The objects and other advantages of this invention can be realized and obtained by means of the structures pointed out in the description, claims, and drawings. Attached Figure Description

[0016] The accompanying drawings are provided to further understand the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation thereof.

[0017] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a schematic diagram of the overall cross-section of this utility model; Figure 3 This is a structural schematic diagram showing a cross-section of the entire utility model along another axis; Figure 4 for Figure 2 Enlarged structural diagram at point A in the middle; Figure 5 for Figure 2 Enlarged structural diagram at point B; Figure 6 for Figure 3 Enlarged structural diagram at point C; Figure 7 for Figure 3 Enlarged structural diagram at point D.

[0018] In the diagram: 1. Support base; 2. Lower rotating disk; 3. Bearing frame; 4. Moving plate; 5. Upper rotating disk; 6. Abutment seat; 7. Rotary motor; 8. Abutment groove; 9. Drive motor; 10. Sliding block; 11. Sliding groove; 12. Drive screw; 13. Positioning seat; 14. Positioning groove; 15. Limiting rod; 16. Limiting groove; 17. Pulling plate; 18. Elastic element; 19. Embedding groove; 20. Ball bearing; 21. Arc groove. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0020] Example 1 Please see Figures 1-7 A cell culture medium separation mechanism includes a support base 1, a lower rotating disk 2 on the upper part of the support base 1, a rotary motor 7 for driving the rotation of the lower rotating disk 2 fixedly installed inside the support base 1, an inverted U-shaped support frame 3 fixedly installed on the side of the support base 1, a movable plate 4 that can move up and down inside the support frame 3, an upper rotating disk 5 adapted to the lower rotating disk 2 rotatably connected to the lower part of the movable plate 4, several abutment seats 6 with one end open on the opposite sides of the lower rotating disk 2 and the upper rotating disk 5, several abutment grooves 8 with different inner diameters and stepped shapes inside the abutment seats 6, two symmetrical and synchronous drive motors 9 fixedly installed on the upper part of the support frame 3, sliding blocks 10 fixedly installed at both ends of the movable plate 4, sliding grooves 11 adapted to the sliding blocks 10 on the opposite side walls inside the support frame 3, a drive screw 12 with one end fixedly installed to the output end of the drive motor 9 rotatably connected inside the sliding groove 11, the drive screw 12 passing through the sliding block 10 and threadedly connected to it.

[0021] In this embodiment, the specific implementation is as follows: When cell culture medium needs to be separated, the cell culture medium is poured into a cell culture flask. The lower end of the cell culture flask is placed in a matching groove 8 within the lower rotating disk 2. Then, two synchronous drive motors 9 are started. The output of the drive motors 9 drives the drive screw 12 to rotate. When the drive screw 12 rotates, the drive sliding block 10 slides within the sliding groove 11. The two sliding blocks 10 drive the moving plate 4 to move downwards. The moving plate 4 drives the upper rotating disk 5 to move downwards. Several abutment seats 6 at the lower part of the upper rotating disk 5 are engaged with the upper part of the cell culture flask. When the rotary motor 7 is turned on, the output end of the rotary motor 7 drives the lower rotating disk 2 to rotate, thereby achieving the effect of separating the cell culture medium in the cell culture flask. The abutment seat 6 is provided with several abutment grooves 8. The inner diameter of each abutment groove 8 is adapted to the outer diameter of commonly used cell culture flasks. The inner side wall of the abutment groove 8 is provided with an elastic pad, which is used to protect the cell culture flask and can limit and fix cell culture flasks of different sizes. The two abutment seats 6 clamp and limit the cell culture flasks, making it easy to pick up and put down the cell culture flasks, while improving the stability of clamping the cell culture flasks.

[0022] Example 2 Please see Figure 7This embodiment includes the above embodiment, and further includes: a positioning seat 13 is fixedly installed on the side of the abutment seat 6 away from the opening end; the sides of the lower rotating disk 2 and the upper rotating disk 5 are provided with positioning grooves 14 that are adapted to the positioning seat 13; a plurality of limiting rods 15 that are adapted to the positions of the positioning grooves 14 are inserted into the sides of the lower rotating disk 2 and the upper rotating disk 5; a limiting groove 16 that is adapted to the end of the limiting rod 15 is opened on one side of the positioning seat 13; a pulling plate 17 is fixedly installed on the outer end of the limiting rod 15; and an elastic element 18 sleeved on the side of the limiting rod 15 is fixedly installed between the pulling plate 17 and the side of the lower rotating disk 2 or the upper rotating disk 5.

[0023] In this embodiment, the specific implementation method is as follows: When installing the abutment seat 6, pull the dragging plate 17 away from the positioning seat 13. The dragging plate 17 drives the limiting rod 15 to move. At this time, the elastic element 18 is stretched, aligning the direction of the limiting groove 16 with the direction of the limiting rod 15. The positioning seat 13 on one side of the abutment seat 6 is inserted into the positioning groove 14. Release the dragging plate 17, and the elastic element 18 contracts. The elastic element 18 drives the limiting rod 15 to move, and one end of the limiting rod 15 is inserted into the limiting groove 16 on the side of the positioning seat 13. This completes the installation of the abutment seat 6, which is convenient for installation and also facilitates the replacement of abutment seats 6 of different sizes according to the size of the cell culture flask, thus improving the applicability of the cell culture medium separation equipment.

[0024] Example 3 Please see Figure 4 This embodiment includes all the above embodiments, and further includes: a ball bearing 20 is provided between the support base 1 and the lower rotating disk 2, the number of the ball bearing 20 is several, a number of embedding grooves 19 are opened on the upper part of the support base 1, the ball bearing 20 is embedded in the embedding grooves 19 and can rotate, and a circular arc groove 21 is opened on the lower part of the lower rotating disk 2, the arc groove 21 is adapted to the ball bearing 20.

[0025] In this embodiment, a number of balls 20 are embedded in a number of slots 19 on the upper part of the support base 1. When the lower rotating disk 2 rotates, the balls 20 roll in the arc-shaped groove 21, which reduces the coefficient of friction experienced by the lower rotating disk 2 when it rotates and reduces the power consumption of the rotating motor 7.

[0026] All of the electrical products mentioned above can be purchased from the market. They are mature technologies and have been fully disclosed, so they will not be repeated in the instruction manual. All of the electrical products mentioned above are equipped with power cords, and they are electrically connected to the external main controller and 220V phase voltage (or 380V line voltage) through the power cords. The main controller can be a conventional known device such as a computer that plays a control role.

[0027] Finally, it should be noted that in the description of this utility model, the terms "vertical," "upper," "lower," "horizontal," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0028] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0029] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A cell culture medium separation mechanism, comprising a support frame (1), characterized in that, The support base (1) is provided with a lower rotating disk (2) on the upper part. A rotary motor (7) for driving the lower rotating disk (2) to rotate is fixedly installed inside the support base (1). A U-shaped support frame (3) is fixedly installed on the side of the support base (1). A movable plate (4) that can move up and down is provided inside the support frame (3). An upper rotating disk (5) that is adapted to the lower rotating disk (2) is rotatably connected to the lower rotating disk (4). Several abutment seats (6) with one end open are provided on the opposite sides of the lower rotating disk (2) and the upper rotating disk (5). Several abutment grooves (8) are provided inside the abutment seats (6). The inner diameter of the several abutment grooves (8) is different and is stepped.

2. The cell culture medium separation mechanism according to claim 1, characterized in that, Two symmetrical and synchronous drive motors (9) are fixedly installed on the upper part of the support frame (3). Sliding blocks (10) are fixedly installed at both ends of the moving plate (4). Sliding grooves (11) adapted to the sliding blocks (10) are opened on the opposite side walls inside the support frame (3). A drive screw (12) with one end fixedly installed to the output end of the drive motor (9) is rotatably connected in the sliding groove (11). The drive screw (12) passes through the sliding block (10) and is threadedly connected to it.

3. The cell culture medium separation mechanism according to claim 1, characterized in that, A positioning seat (13) is fixedly installed on the side of the abutment seat (6) away from the opening end. The sides of the lower rotating plate (2) and the upper rotating plate (5) are provided with positioning grooves (14) that are compatible with the positioning seat (13).

4. The cell culture medium separation mechanism according to claim 3, characterized in that, Several limiting rods (15) adapted to the position of the positioning groove (14) are inserted into the sides of the lower rotating disk (2) and the upper rotating disk (5). A limiting groove (16) adapted to the end of the limiting rod (15) is opened on one side of the positioning seat (13). A pulling plate (17) is fixedly installed on the outer end of the limiting rod (15). An elastic element (18) sleeved on the side of the limiting rod (15) is fixedly installed between the pulling plate (17) and the side of the lower rotating disk (2) or the upper rotating disk (5).

5. The cell culture medium separation mechanism according to claim 1, characterized in that, There are several balls (20) between the support base (1) and the lower rotating disk (2).

6. The cell culture medium separation mechanism according to claim 5, characterized in that, The upper part of the support base (1) has several embedding slots (19), and the ball bearings (20) are embedded in the embedding slots (19) and can rotate.

7. The cell culture medium separation mechanism according to claim 5, characterized in that, The lower rotating disk (2) has a circular arc groove (21) at the bottom, which is adapted to the ball (20).

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